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Evidence of Interaction Between EGFR and CBL

The interaction score between EGFR and CBL is 67.1.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismEGFR OrthologueCBL OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00298285 0.165 IPI00292856 0.232
fly P04412 0.165 Q9VSK2 0.118

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in EGFR and CBL:
Domains in EGFRDomains in CBL
IPR000494 Epidermal growth-factor receptor (EGFR), L domain
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR001450 4Fe-4S ferredoxin, iron-sulfur binding domain
IPR006211 Furin-like cysteine rich region
IPR006212 Furin-like repeat
IPR008266 Tyrosine protein kinase, active site
IPR009030 Growth factor, receptor
IPR011009 Protein kinase-like
IPR001841 Zn-finger, RING
IPR000449 Ubiquitin-associated domain
IPR000980 SH2 motif
IPR000217 Tubulin
IPR003153 Adaptor protein Cbl, N-terminal
IPR011992 EF-Hand_type.
IPR013090 Phospholip_A2_AS.

The Chi square scores for co-occurrence of domains that are present in EGFR and CBL are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR000494 Epidermal growth-factor receptor (EGFR), L domain IPR000980 SH2 motif 46.2087
IPR006211 Furin-like cysteine rich region IPR000980 SH2 motif 46.2087
IPR006212 Furin-like repeat IPR000980 SH2 motif 43.075
IPR008266 Tyrosine protein kinase, active site IPR001841 Zn-finger, RING 16.2425
IPR011009 Protein kinase-like IPR001841 Zn-finger, RING 15.6712
IPR000719 Protein kinase IPR011992 EF-Hand_type. 15.5567
IPR001245 Tyrosine protein kinase IPR001841 Zn-finger, RING 15.1425
IPR001450 4Fe-4S ferredoxin, iron-sulfur binding domain IPR000980 SH2 motif 14.6486
IPR000719 Protein kinase IPR001841 Zn-finger, RING 14.0542
IPR008266 Tyrosine protein kinase, active site IPR003153 Adaptor protein Cbl, N-terminal 13.6309
IPR009030 Growth factor, receptor IPR000980 SH2 motif 10.8957
IPR011009 Protein kinase-like IPR011992 EF-Hand_type. 9.34155
IPR001245 Tyrosine protein kinase IPR003153 Adaptor protein Cbl, N-terminal 9.19853
IPR001245 Tyrosine protein kinase IPR011992 EF-Hand_type. 6.38624
IPR000719 Protein kinase IPR003153 Adaptor protein Cbl, N-terminal 3.06419
IPR011009 Protein kinase-like IPR003153 Adaptor protein Cbl, N-terminal 3.04324
IPR008266 Tyrosine protein kinase, active site IPR011992 EF-Hand_type. 1.24952
IPR009030 Growth factor, receptor IPR011992 EF-Hand_type. 1.22286
IPR011009 Protein kinase-like IPR000217 Tubulin 0.524874
IPR011009 Protein kinase-like IPR000449 Ubiquitin-associated domain 0.41941
IPR001245 Tyrosine protein kinase IPR000449 Ubiquitin-associated domain 0.348773
IPR001450 4Fe-4S ferredoxin, iron-sulfur binding domain IPR011992 EF-Hand_type. 0.200923
IPR008266 Tyrosine protein kinase, active site IPR000217 Tubulin 0.0503676
IPR000719 Protein kinase IPR000217 Tubulin 0.0254403
IPR006212 Furin-like repeat IPR011992 EF-Hand_type. 0.00617113
IPR008266 Tyrosine protein kinase, active site IPR000449 Ubiquitin-associated domain 0.00515077
IPR000719 Protein kinase IPR000449 Ubiquitin-associated domain 0.00138935
IPR001245 Tyrosine protein kinase IPR000217 Tubulin 0.00033966
IPR000494 Epidermal growth-factor receptor (EGFR), L domain IPR011992 EF-Hand_type. 0.000103322
IPR006211 Furin-like cysteine rich region IPR011992 EF-Hand_type. 0.000103322

The background colour of the table refers to:

  • Blue Domain is only present in EGFR
  • Yellow Domain is only present in CBL
  • Green Domain is present in both EGFR and CBL

 0.540
Post-translational Modifications

Protein: EGFR

PTMResidueReference
Dephosphorylation 1016 PubMed, HPRD
Dephosphorylation 1197 PubMed, HPRD
Disulfide Bridge 58 PubMed, HPRD
Disulfide Bridge 187 PubMed, HPRD
Disulfide Bridge 199 PubMed, HPRD
Disulfide Bridge 207 PubMed, HPRD
Disulfide Bridge 223 PubMed, HPRD
Disulfide Bridge 231 PubMed, HPRD
Disulfide Bridge 240 PubMed, HPRD
Disulfide Bridge 248 PubMed, HPRD
Disulfide Bridge 260 PubMed, HPRD
Disulfide Bridge 291 PubMed, HPRD
Disulfide Bridge 307 PubMed, HPRD
Disulfide Bridge 326 PubMed, HPRD
Disulfide Bridge 333 PubMed, HPRD
Disulfide Bridge 362 PubMed, HPRD
Disulfide Bridge 499 PubMed, HPRD
Disulfide Bridge 515 PubMed, HPRD
Disulfide Bridge 523 PubMed, HPRD
Disulfide Bridge 535 PubMed, HPRD
Disulfide Bridge 555 PubMed, HPRD
Disulfide Bridge 571 PubMed, HPRD
Disulfide Bridge 579 PubMed, HPRD
Disulfide Bridge 591 PubMed, HPRD
Disulfide Bridge 617 PubMed, HPRD
Disulfide Bridge 628 PubMed, HPRD
Disulfide Bridge 636 PubMed, HPRD
Glycosylation 56 PubMed, HPRD
Glycosylation 128 PubMed, HPRD
Glycosylation 175 PubMed, HPRD
Glycosylation 196 PubMed, HPRD
Glycosylation 352 PubMed, HPRD
Glycosylation 361 PubMed, HPRD
Glycosylation 413 PubMed, HPRD
Glycosylation 444 PubMed, HPRD
Glycosylation 528 PubMed, HPRD
Glycosylation 568 PubMed, HPRD
Glycosylation 603 PubMed, HPRD
Glycosylation 623 PubMed, HPRD
N-linked 56 PubMed, HPRD
N-linked 128 PubMed, HPRD
N-linked 175 PubMed, HPRD
N-linked 352 PubMed, HPRD
N-linked 361 PubMed, HPRD
N-linked 413 PubMed, HPRD
N-linked 444 PubMed, HPRD
N-linked 528 PubMed, HPRD
N-linked 568 PubMed, HPRD
N-linked 603 PubMed, HPRD
Phosphorylation 678 PubMed, HPRD
Phosphorylation 693 PubMed, HPRD
Phosphorylation 695 PubMed, HPRD
Phosphorylation 768 PubMed, HPRD
Phosphorylation 869 PubMed, HPRD
Phosphorylation 915 PubMed, HPRD
Phosphorylation 944 PubMed, HPRD
Phosphorylation 998 PubMed, HPRD
Phosphorylation 1016 PubMed, HPRD
Phosphorylation 1064 PubMed, HPRD
Phosphorylation 1069 PubMed, HPRD
Phosphorylation 1070 PubMed, HPRD
Phosphorylation 1071 PubMed, HPRD
Phosphorylation 1081 PubMed, HPRD
Phosphorylation 1092 PubMed, HPRD
Phosphorylation 1110 PubMed, HPRD
Phosphorylation 1120 PubMed, HPRD
Phosphorylation 1125 PubMed, HPRD
Phosphorylation 1166 PubMed, HPRD
Phosphorylation 1172 PubMed, HPRD
Phosphorylation 1197 PubMed, HPRD
Phosphoserine 695 PubMed, HPRD
Phosphoserine 1070 HPRD
Phosphoserine 1071 HPRD
Phosphothreonine 678 PubMed, HPRD
Phosphothreonine 693 HPRD
Phosphotyrosine 1092 PubMed, HPRD
Phosphotyrosine 1110 PubMed, HPRD
Phosphotyrosine 1172 PubMed, HPRD
Phosphotyrosine 1197 PubMed, HPRD

Protein: CBL

PTMResidueReference
Phosphorylation 371 PubMed, HPRD
Phosphorylation 619 PubMed, HPRD
Phosphorylation 623 PubMed, HPRD
Phosphorylation 639 PubMed, HPRD
Phosphorylation 642 PubMed, HPRD
Phosphorylation 667 PubMed, HPRD
Phosphorylation 669 PubMed, HPRD
Phosphorylation 674 PubMed, HPRD
Phosphorylation 675 PubMed, HPRD
Phosphorylation 700 PubMed, HPRD
Phosphorylation 731 PubMed, HPRD
Phosphorylation 774 PubMed, HPRD
Phosphoserine 669 HPRD
Phosphotyrosine 371 PubMed, HPRD
Phosphotyrosine 674 HPRD
Phosphotyrosine 700 HPRD
Phosphotyrosine 774 HPRD
Localisation

Protein: EGFR

LocalisationReference
Golgi HPRD
Nucleus HPRD
Plasma membrane HPRD
Endosome HPRD
Nucleolus PubMed, HPRD
Secreted HPRD
Cytoplasm HPRD

Protein: CBL

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between EGFR and CBL that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EGFR andCBL. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EGFR has 1581 interactors and CBL has 1376 interactors of which there are 696 common interactors.

Common InteractorName of Common InteractorScore for EGFR-Interactor (?)Score for CBL-Interactor (?)
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 93.60 5.94
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 71.20 0.318
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 46.90 0.577
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 35.90 0.483
SHC2 N/A 12.40 1.29
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 1.37 0.140
LOC392481 N/A 1.07 1.07
SHC4 SHC-transforming protein 4 1.07 1.07
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.980 0.072
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.109
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.980 0.081
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.980 0.644
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.980 1.13
LYN LYN: Tyrosine-protein kinase Lyn 0.980 0.655
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.980 0.902
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 0.980
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.980 0.731
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.980 0.072
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.980 0.100
STAT3 0.980 0.098
BMX N/A 0.980 0.644
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 0.980
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.109
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.109
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.980 0.081
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.980 0.731
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.980 0.081
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.980 0.577
HCK N/A 0.878 0.655
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.878 8.34
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.878 1.01
STAT6 STAT6: Signal transducer and activator of transcription 6 0.878 0.073
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.878 0.090
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.878 0.655
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.878 0.655
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.878 0.064
CSK CSK: Tyrosine-protein kinase CSK 0.878 0.655
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.878 0.577
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.878 0.655
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.878 0.577
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.878 277.00
CRKL CRKL: Crk-like protein 0.878 0.064
RIN1 RIN1: Ras and Rab interactor 1 0.878 0.097
NCK2 NCK2: Cytoplasmic protein NCK2 0.878 30.80
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.878 0.098
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.878 0.655
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.878 0.878
APS SH2B2, APS: SH2B adapter protein 2 0.878 0.073
SYK SYK: Tyrosine-protein kinase SYK 0.878 0.808
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.878 0.064
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.878 0.073
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.878 0.577
JAK1 0.878 0.577
VAV1 VAV1, VAV: Proto-oncogene vav 0.878 0.073
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.878 0.878
GRB10 N/A 0.617 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.051
CRK CRK: Proto-oncogene C-crk 0.617 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.051
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.553 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.046
STAT2 STAT2: Signal transducer and activator of transcription 2 0.540 0.152
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.540 0.123
STAT4 STAT4: Signal transducer and activator of transcription 4 0.540 0.111
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.540 0.109
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.483 0.148
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.483 0.097
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.483 0.097
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.217
FYN N/A 0.217 0.143
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.217 0.143
GRAP GRAP: GRB2-related adapter protein 0.195 2.13
FN1 N/A 0.174 0.0688
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.540
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.0688
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.165 0.051
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.0688
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.0688
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.165 0.051
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.165 0.051
GHR GHR: Growth hormone receptor precursor 0.165 0.051
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.540
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.165 0.045
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.165 0.045
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.0688
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.165 0.045
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.165 0.051
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.165 0.051
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.165 0.051
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.165 0.034
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.165 0.045
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.165 0.045
SORL1 SORL1: Sortilin-related receptor precursor 0.165 0.051
KIR3DL1 N/A 0.165 0.0688
ITGB4 N/A 0.165 0.051
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.0688
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.165 0.045
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.0688
CRLF3 N/A 0.165 0.045
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.165 0.051
IL9R IL9R: Interleukin-9 receptor precursor 0.165 0.051
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.165 0.063
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.165 0.041
GPA33 GPA33: Cell surface A33 antigen precursor 0.165 0.051
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.165 0.051
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.165 0.100
LILRB1 N/A 0.165 0.063
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.0688
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.165 0.445
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.540
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.0688
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.165 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.165 0.051
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.165 0.045
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.165 0.403
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.165 0.051
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.165 0.045
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.165 0.045
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.165 0.045
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.165 0.063
EGF EGF: Pro-epidermal growth factor precursor 0.165 0.051
PVR PVR, PVS: Poliovirus receptor precursor 0.165 0.051
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.165 0.051
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.0688
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.165 0.051
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.0688
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.165 0.051
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.165 0.051
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.0688
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.165 0.051
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.0688
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.0688
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.165 0.063
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.165 0.051
F3 F3: Tissue factor precursor 0.165 0.051
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.165 0.051
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.165 0.045
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.165 0.045
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.165 0.051
PRLR PRLR: Prolactin receptor precursor 0.165 0.063
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.165 0.051
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.165 0.051
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.0688
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.165 0.045
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.165 0.051
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.165 0.051
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.165 0.063
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.165 0.063
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.165 0.045
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.165 0.041
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.165 0.025
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.165 0.051
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.165 0.051
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.165 0.025
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.0688
CD7 CD7: T-cell antigen CD7 precursor 0.165 0.045
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.165 0.045
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.165 0.320
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.0688
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.165 0.063
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.165 0.051
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.0688
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.165 0.051
SELE SELE, ELAM1: E-selectin precursor 0.165 0.025
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.165 0.045
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.0688
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.0688
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.165 0.051
EPOR EPOR: Erythropoietin receptor precursor 0.165 0.051
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.165 0.045
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.165 0.063
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.148 0.361
TNC TNC, HXB: Tenascin precursor 0.148 0.037
MEP1B MEP1B: Meprin A subunit beta precursor 0.148 0.057
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.148 137.00
JAG2 JAG2: Jagged-2 precursor 0.148 0.030
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.062
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.148 0.318
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.148 0.445
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.062
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.148 173.00
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.062
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.148 0.057
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.148 214.00
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.148 0.361
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.148 0.445
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.148 0.041
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.062
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.148 0.041
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.148 0.046
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.148 0.445
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.148 0.041
DCC DCC: Netrin receptor DCC precursor 0.148 0.057
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.148 0.318
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.148 0.318
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.148 0.041
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.483
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.148 0.286
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.148 0.361
KIT KIT: Mast/stem cell growth factor receptor precursor 0.148 0.318
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.062
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.148 0.073
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.148 0.286
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.148 0.318
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.148 0.041
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.148 0.028
BSG N/A 0.148 0.062
NEO1 NEO1, NGN: Neogenin precursor 0.148 0.057
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 0.062
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.148 0.046
INSR INSR: Insulin receptor precursor 0.148 0.318
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.062
PTPRZ1 N/A 0.148 0.037
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.148 0.318
ATRN N/A 0.148 0.030
MEP1A MEP1A: Meprin A subunit alpha precursor 0.148 0.037
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.109 0.072
GRLF1 N/A 0.109 0.127
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.109 0.072
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.109 0.045
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.109 0.029
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.109 0.081
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.109
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.109 0.123
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.109
CSPG2 N/A 0.109 0.051
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.109 0.045
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.049
GAB1 GAB1: GRB2-associated-binding protein 1 0.109 0.109
CNN2 CNN2: Calponin-2 0.109 0.109
SPTAN1 N/A 0.109 0.072
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.109 0.051
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.109
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.109 0.032
NF2 NF2, SCH: Merlin 0.109 0.165
FUBP1 N/A 0.109 0.037
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.109 0.072
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.109
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.109 0.035
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.109 0.036
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.109 0.081
GAB2 N/A 0.109 0.109
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.109 0.030
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.109 0.081
IRS2 IRS2: Insulin receptor substrate 2 0.109 0.109
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.109 0.037
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.109 0.044
F5 F5: Coagulation factor V precursor 0.109 0.031
IRS1 IRS1: Insulin receptor substrate 1 0.109 0.152
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.049
PPEF1 N/A 0.109 0.165
CNN3 CNN3: Calponin-3 0.109 0.065
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.109 0.051
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.109 0.123
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.109 0.123
VASP VASP: Vasodilator-stimulated phosphoprotein 0.109 0.072
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.109 0.045
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.109 0.045
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.109 0.045
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.109 0.0263
S100A3 S100A3, S100E: Protein S100-A3 0.109 0.037
ROCK1 ROCK1: Rho-associated protein kinase 1 0.109 0.152
PSCD2 N/A 0.109 0.109
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.109 0.123
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.109
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.109 0.0263
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.109 0.045
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.081
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.109
EEF2K EEF2K: Elongation factor 2 kinase 0.109 0.148
S100B S100B: Protein S100-B 0.109 0.029
CTTN CTTN, EMS1: Src substrate cortactin 0.109 0.065
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.049
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.098 0.111
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.098 0.171
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.098 0.111
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.098 0.027
STAM2 STAM2: Signal transducing adapter molecule 2 0.098 0.148
PSD TYL: TYL protein 0.098 0.058
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.098 0.073
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.098 0.111
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.098 0.136
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.098 0.111
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.098 0.097
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.098 0.111
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.098 0.029
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.098 0.073
VWF VWF, F8VWF: von Willebrand factor precursor 0.098 0.041
DOK1 DOK1: Docking protein 1 0.098 0.111
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 0.878
SORBS3 SORBS3, SCAM1: Vinexin 0.098 43.20
TLN2 TLN2: Uncharacterized protein TLN2 0.098 0.064
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.098 0.041
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.098 0.090
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.098 0.041
DAB2 DAB2, DOC2: Disabled homolog 2 0.098 0.097
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.098
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.098 0.058
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.098 0.058
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.098 0.111
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.098 0.073
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.098
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.098 0.041
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.098 0.058
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.098
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.098 0.036
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.098 0.064
CD2AP CD2AP: CD2-associated protein 0.098 0.090
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.098 0.033
PLD1 PLD1: Phospholipase D1 0.098 0.073
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.036
CXorf9 N/A 0.098 0.111
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.098 0.064
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.098 0.097
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.098 0.148
RDX RDX: Radixin 0.098 0.064
PSCD4 PSCD4, CYT4: Cytohesin-4 0.098 0.090
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.098 0.041
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.025
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.098 0.073
ELMO1 N/A 0.098 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.098
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.098 0.029
RASA3 RASA3: Ras GTPase-activating protein 3 0.098 0.073
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.098 0.073
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.098 0.041
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.044
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.098 0.097
ACTN1 ACTN1: Alpha-actinin-1 0.098 0.064
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.098
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.098 0.064
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.098 0.064
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.098 0.136
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.098 0.097
TLN1 TLN1: Uncharacterized protein TLN1 0.098 0.064
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.098
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.098 0.064
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.098
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.098 0.071
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.098 0.088
DLG2 DLG2: Disks large homolog 2 0.098 0.046
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.098 0.111
MSN MSN: Moesin 0.098 0.064
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.025
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.098 0.058
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.098 0.041
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.098 0.029
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.098 0.037
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.098 0.073
VIL2 N/A 0.098 0.064
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.098 0.073
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.098 0.111
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.098 0.111
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.098 0.111
ARHGEF7 N/A 0.098 0.098
TTN N/A 0.098 0.136
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.098 0.064
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.098
DAB1 DAB1: Disabled homolog 1 0.098 0.097
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
GMIP GMIP: GEM-interacting protein 0.098 0.033
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.098 0.030
FNBP1 N/A 0.098 0.111
LCP1 LCP1, PLS2: Plastin-2 0.098 0.073
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.098 0.097
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.098 0.090
PLD2 PLD2: Phospholipase D2 0.098 0.064
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.098 0.073
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.098 0.090
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.098 0.098
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.152
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.096 0.051
S100A7 S100A7, PSOR1: Protein S100-A7 0.096 0.032
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.096 0.045
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.086 0.028
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.083 0.034
GABRR1 N/A 0.083 0.051
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.083 0.152
CCR5 CCR5: CCR5 receptor (Fragment) 0.083 0.063
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.083 0.034
GP1BA N/A 0.083 0.025
MT3 MT3: Metallothionein-3 0.083 0.026
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.083 0.051
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.083 0.025
FADD FADD, MORT1: Protein FADD 0.083 0.045
GP9 GP9: Platelet glycoprotein IX precursor 0.083 0.025
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.0688
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.083 0.361
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.083 0.051
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.083 0.051
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.083 0.025
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.083 0.025
MET MET: Hepatocyte growth factor receptor precursor 0.083 0.403
OPTC OPTC, OPT: Opticin precursor 0.083 0.034
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.083 0.0688
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.034
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.0688
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.083 0.063
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.083 0.051
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.075 0.073
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.030
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.062
GLRA1 N/A 0.075 0.057
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.075 0.483
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.030
HPN HPN, TMPRSS1: Serine protease hepsin 0.075 0.028
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.075 0.046
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.075 0.041
GLRB GLRB: Glycine receptor subunit beta precursor 0.075 0.037
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.0688 0.098
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.0688 0.097
PLEK PLEK, P47: Pleckstrin 0.0688 0.152
RYR2 RYR2: Ryanodine receptor 2 0.0688 0.045
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.0688 0.109
CENTA1 CENTA1: Centaurin-alpha 1 0.0688 0.041
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.0688 0.152
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.0688 0.123
RYR1 0.0688 0.071
NSBP1 NSBP1: Nucleosome-binding protein 1 0.0688 0.028
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.062 0.136
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.062 0.088
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.062 0.088
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.062 0.111
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.062 0.097
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.148
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.062 0.097
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.062 0.097
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.062 0.111
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.062 0.111
SOS1 SOS1: Son of sevenless homolog 1 0.062 0.136
CETN1 CETN1, CEN1, CETN: Centrin-1 0.062 0.047
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.148
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.062 0.097
ANXA3 ANXA3, ANX3: Annexin A3 0.052 0.051
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.052 0.034
ANXA9 ANXA9, ANX31: Annexin A9 0.052 0.063
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.052 0.045
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.052 0.045
NULL Ig lambda chain V-I region EPS 0.051 0.051
UBAP2L N/A 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
HLA-A N/A 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
IGHG3 N/A 0.051 0.051
IGHM N/A 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
RAPH1 N/A 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
IGHA1 N/A 0.051 0.051
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.051 0.047
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
C9orf88 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
IGHD N/A 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
MARK2 N/A 0.051 0.051
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.051 0.0338
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.051 0.038
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
CNN1 CNN1: Calponin-1 0.051 0.0338
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
NCAM1 N/A 0.051 0.051
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.051 0.042
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.049 0.041
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.049 0.123
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.049 1.20
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.049 0.049
PRPH PRPH, NEF4, PRPH1: Peripherin 0.049 0.0453
MAP2K5 N/A 0.049 0.109
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.049 0.081
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.049 0.029
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.049 0.081
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.049 0.029
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.049 0.136
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.049 0.064
GFAP GFAP: Glial fibrillary acidic protein 0.049 0.029
LIPG LIPG, UNQ387/PRO719: Endothelial lipase precursor 0.049 0.031
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.049 0.0453
DES DES: Desmin 0.049 0.032
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.049 0.065
DCN DCN: Decorin precursor 0.049 0.034
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.049 0.04
FLNA FLNA, FLN, FLN1: Filamin-A 0.049 0.072
COBL N/A 0.049 0.065
KERA KERA: Keratocan precursor 0.049 0.025
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.109
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.049 0.088
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.049 0.152
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.049 0.109
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.049 0.055
GAS2 GAS2: Growth arrest-specific protein 2 0.049 0.072
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.047 0.046
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.047 0.041
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.030
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.046 0.053
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
LMO7 N/A 0.046 0.046
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
TNN TNN: Tenascin-N precursor 0.046 0.034
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.046 0.034
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.044 0.088
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.044 0.064
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.044 0.088
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.044 0.064
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.044 0.064
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.044 0.033
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.044 0.111
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.044 0.111
THOC1 THOC1, HPR1: THO complex subunit 1 0.044 0.073
WWC1 WWC1, KIAA0869: WW domain-containing protein 1 0.044 0.049
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.044 0.090
PARVA PARVA, MXRA2: Alpha-parvin 0.044 0.064
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.044 0.097
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.044 0.049
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.044 0.073
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.044 0.041
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.044 0.073
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.044 0.090
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.044 0.064
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.097
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.044 0.027
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.044 0.090
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.044 0.111
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.044
ALK ALK: ALK tyrosine kinase receptor precursor 0.044 0.445
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.044 0.073
IGFALS IGFALS, ALS: Insulin-like growth factor-binding protein complex acid labile chai 0.044 0.028
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.044 0.097
ATM ATM: Serine-protein kinase ATM 0.044 0.111
WASPIP N/A 0.044 0.073
RAB11FIP5 RAB11FIP5, GAF1, KIAA0857, RIP11: Rab11 family-interacting protein 5 0.044 0.051
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.04 0.109
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.04 0.191
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.04 0.090
CASP9 CASP9, MCH6: Caspase-9 precursor 0.04 0.109
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.04 0.029
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.049
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.04 0.152
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.04 0.152
MAPK15 N/A 0.04 0.165
STK16 N/A 0.04 0.152
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.04 0.033
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.04 0.123
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.04 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.04 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.04 0.148
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.040 0.037
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.036 0.051
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.036 0.064
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.036 0.033
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.036 0.111
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.036 0.029
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.036 0.033
PMP2 PMP2: Myelin P2 protein 0.036 0.026
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.036 0.171
WWC2 WW and C2 domain containing 2 0.036 0.033
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.036 0.033
RPS6KB1 N/A 0.036 0.097
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.036 0.097
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.036 0.064
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.036 0.148
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.036 0.046
HDLBP HDLBP, HBP, VGL: Vigilin 0.036 0.033
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.036 0.111
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.036 0.111
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.036 0.029
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.036 0.027
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.036 0.097
FLII FLII, FLIL: Protein flightless-1 homolog 0.036 0.051
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.036 0.111
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.036 0.111
RPS10 RPS10: 40S ribosomal protein S10 0.036 0.064
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.036 0.111
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.036 0.136
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.034 0.026
ETS2 ETS2: Protein C-ets-2 0.034 0.109
MAL2 MAL2: Protein MAL2 0.034 0.034
RAP1GA1 N/A 0.034 0.025
KRT18 KRT18: Uncharacterized protein KRT18 0.034 0.034
VIM VIM: Vimentin 0.034 0.055
MDM4 MDM4, MDMX: Mdm4 protein 0.034 0.062
XRCC1 XRCC1: DNA-repair protein XRCC1 0.034 0.049
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.034 0.039
OCLN OCLN: Occludin 0.034 0.031
TP73 TP73, P73: Tumor protein p73 0.034 0.109
BID BID: BH3-interacting domain death agonist 0.034 0.028
SCML2 SCML2: Sex comb on midleg-like protein 2 0.034 0.152
CCNH CCNH: Cyclin-H 0.030 0.035
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.030 0.136
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.030 0.025
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.030 0.056
CCNT2 CCNT2: Cyclin-T2 0.030 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.030 0.025
CREB1 CREB1: cAMP response element-binding protein 0.030 0.025
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.030
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.030 0.035
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.030 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.148
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.030 0.047
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.030 0.069
MCOLN1 MCOLN1, ML4, MSTP080: Mucolipin-1 0.030 0.041
LMNA LMNA, LMN1: Lamin-A/C 0.030 0.025
CCNB1 Cyclin B1 0.030 0.035
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.030 0.069
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.029 0.027
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.028 0.030
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.028 0.039
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.028 0.041
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.034
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.028 0.045
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.028 0.034
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.028 0.031
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.028 0.034
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.028 0.025
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.028 0.025
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.034
TNFRSF10C TNFRSF10C, DCR1, UNQ321/PRO366, LIT, TRAILR3, TRID: Tumor necrosis factor recept 0.028 0.051
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.028 0.025
DRD2 DRD2: D(2) dopamine receptor 0.028 0.034
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.027 0.051
FGFR2 N/A 0.027 0.141
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.027 0.0924
TYRO3 TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor 0.027 0.0924
FES N/A 0.0258 0.0258
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.025 0.030
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.062
ASGR1 ASGR1: Asialoglycoprotein receptor 1 0.025 0.028
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.025 0.098
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.025 0.064
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.025 0.037
TSHR N/A 0.025 0.035
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.025 0.073
ADCY3 ADCY3, KIAA0511: Adenylate cyclase type 3 0.025 0.041
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.062
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.025 0.041
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.025 0.073
0.347
Total Score 67.1