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Evidence of Interaction Between PSMC3 and TBP

The interaction score between PSMC3 and TBP is 272.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between PSMC3 and TBP = 0.41

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

4.62E-3
Orthology
OrganismPSMC3 OrthologueTBP OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YOR117W 1 YER148W 1
  • Other
  • AffinityCaptureMS

Get References From PubMed

worm O76371 1 P32085 1
fly Q9V3V6 1 P20227 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.593
Domains No domains were used in calculating likelihood of interaction 5.15E-3
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: PSMC3

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: TBP

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between PSMC3 and TBP that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PSMC3 andTBP. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PSMC3 has 132 interactors and TBP has 180 interactors of which there are 13 common interactors.

Common InteractorName of Common InteractorScore for PSMC3-Interactor (?)Score for TBP-Interactor (?)
PSMC5 PSMC5, SUG1: 26S protease regulatory subunit 8 6.33 1.22
RANBP5 4.88 6.05
PSMD13 PSMD13: 26S proteasome non-ATPase regulatory subunit 13 1.82 0.494
RAD23B RAD23B: UV excision repair protein RAD23 homolog B 1.82 0.538
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 1.01 0.890
RAD23A RAD23A: UV excision repair protein RAD23 homolog A 0.132 0.065
RANBP6 N/A 0.119 0.119
NULL N/A 0.119 0.119
NULL N/A 0.119 0.119
RUVBL1 RUVBL1, NMP238, TIP49, TIP49A: RuvB-like 1 0.060 3.08
RUVBL2 RUVBL2, TIP48, CGI-46, TIP49B: RuvB-like 2 0.044 3.82
TBPL2 0.039 0.071
CTNNBL1 N/A 0.0255 0.0255
0.299
Total Score 272.00