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Evidence of Interaction Between F2 and THBD

The interaction score between F2 and THBD is 29.70.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between F2 and THBD = 0.00

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.85E-3
Orthology N/A N/A
Domains Domains present in F2 and THBD:
Domains in F2Domains in THBD
IPR000001 Kringle
IPR001254 Peptidase S1, chymotrypsin
IPR001314 Peptidase S1A, chymotrypsin
IPR009003 Peptidase, trypsin-like serine and cysteine proteases
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region
IPR002383 Coagulation factor, Gla region
IPR003966 Peptidase S1A, prothrombin
IPR012051 Thrombin.
IPR000152 Aspartic acid and asparagine hydroxylation site
IPR001881 EGF-like calcium-binding
IPR006209 EGF-like domain
IPR006210 Type I EGF
IPR001304 C-type lectin
IPR001491 Thrombomodulin
IPR000742 EGF_2.
IPR013032 IPR006209.
IPR013091 EGF_Ca_bd_2.

The Chi square scores for co-occurrence of domains that are present in F2 and THBD are listed below.

Domain 1Domain 2Chi Square
IPR002383 Coagulation factor, Gla region IPR000152 Aspartic acid and asparagine hydroxylation site 56.5311
IPR002383 Coagulation factor, Gla region IPR001881 EGF-like calcium-binding 55.1239
IPR002383 Coagulation factor, Gla region IPR000742 EGF_2. 53.7358
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR000152 Aspartic acid and asparagine hydroxylation site 53.6016
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR001881 EGF-like calcium-binding 52.2522
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR000742 EGF_2. 50.727
IPR001314 Peptidase S1A, chymotrypsin IPR013032 IPR006209. 43.7147
IPR001254 Peptidase S1, chymotrypsin IPR013032 IPR006209. 42.0976
IPR002383 Coagulation factor, Gla region IPR006209 EGF-like domain 39.6754
IPR001314 Peptidase S1A, chymotrypsin IPR006209 EGF-like domain 38.8415
IPR001314 Peptidase S1A, chymotrypsin IPR000742 EGF_2. 38.8083
IPR002383 Coagulation factor, Gla region IPR006210 Type I EGF 38.5353
IPR002383 Coagulation factor, Gla region IPR013032 IPR006209. 38.3622
IPR001254 Peptidase S1, chymotrypsin IPR000742 EGF_2. 37.3069
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR006209 EGF-like domain 37.2603
IPR001254 Peptidase S1, chymotrypsin IPR006209 EGF-like domain 37.2501
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR006210 Type I EGF 36.3514
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR000742 EGF_2. 36.1318
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR013032 IPR006209. 36.1244
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR006209 EGF-like domain 34.703
IPR001314 Peptidase S1A, chymotrypsin IPR006210 Type I EGF 33.1435
IPR001254 Peptidase S1, chymotrypsin IPR006210 Type I EGF 31.89
IPR001314 Peptidase S1A, chymotrypsin IPR000152 Aspartic acid and asparagine hydroxylation site 31.2445
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR013032 IPR006209. 30.9736
IPR001314 Peptidase S1A, chymotrypsin IPR001881 EGF-like calcium-binding 30.146
IPR001254 Peptidase S1, chymotrypsin IPR000152 Aspartic acid and asparagine hydroxylation site 30.1273
IPR001254 Peptidase S1, chymotrypsin IPR001881 EGF-like calcium-binding 29.0541
IPR000001 Kringle IPR006209 EGF-like domain 27.7846
IPR000001 Kringle IPR000742 EGF_2. 27.4564
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR000152 Aspartic acid and asparagine hydroxylation site 26.9841
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR001881 EGF-like calcium-binding 26.0504
IPR000001 Kringle IPR013032 IPR006209. 24.7346
IPR000001 Kringle IPR006210 Type I EGF 20.7416
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR006210 Type I EGF 18.9004
IPR003966 Peptidase S1A, prothrombin IPR013032 IPR006209. 16.0978
IPR000001 Kringle IPR000152 Aspartic acid and asparagine hydroxylation site 13.4788
IPR000001 Kringle IPR001881 EGF-like calcium-binding 13.008
IPR002383 Coagulation factor, Gla region IPR013091 EGF_Ca_bd_2. 11.9479
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR013091 EGF_Ca_bd_2. 11.2434
IPR003966 Peptidase S1A, prothrombin IPR006209 EGF-like domain 9.68573
IPR003966 Peptidase S1A, prothrombin IPR000742 EGF_2. 9.58987
IPR003966 Peptidase S1A, prothrombin IPR006210 Type I EGF 9.24388
IPR012051 Thrombin. IPR013032 IPR006209. 8.35366
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR013091 EGF_Ca_bd_2. 8.1797
IPR001314 Peptidase S1A, chymotrypsin IPR013091 EGF_Ca_bd_2. 8.16422
IPR001254 Peptidase S1, chymotrypsin IPR013091 EGF_Ca_bd_2. 7.81429
IPR012051 Thrombin. IPR000742 EGF_2. 7.53257
IPR000001 Kringle IPR001304 C-type lectin 7.50788
IPR001314 Peptidase S1A, chymotrypsin IPR001304 C-type lectin 5.4065
IPR001254 Peptidase S1, chymotrypsin IPR001304 C-type lectin 5.16544
IPR012051 Thrombin. IPR006209 EGF-like domain 5.13532
IPR012051 Thrombin. IPR006210 Type I EGF 4.49559
IPR003966 Peptidase S1A, prothrombin IPR000152 Aspartic acid and asparagine hydroxylation site 1.30838
IPR003966 Peptidase S1A, prothrombin IPR001881 EGF-like calcium-binding 1.23336
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR001304 C-type lectin 0.347128

The background colour of the table refers to:

  • Blue Domain is only present in F2
  • Yellow Domain is only present in THBD
  • Green Domain is present in both F2 and THBD

 0.174
Post-translational Modifications

Protein: F2

PTMResidueReference
4-carboxyglutamate 49 HPRD
4-carboxyglutamate 50 HPRD
4-carboxyglutamate 57 HPRD
4-carboxyglutamate 59 HPRD
4-carboxyglutamate 62 HPRD
4-carboxyglutamate 63 HPRD
4-carboxyglutamate 68 HPRD
4-carboxyglutamate 69 HPRD
4-carboxyglutamate 72 HPRD
4-carboxyglutamate 75 HPRD
Carboxylation 49 PubMed, HPRD
Carboxylation 50 PubMed, HPRD
Carboxylation 57 PubMed, HPRD
Carboxylation 59 PubMed, HPRD
Carboxylation 62 PubMed, HPRD
Carboxylation 63 PubMed, HPRD
Carboxylation 68 PubMed, HPRD
Carboxylation 69 PubMed, HPRD
Carboxylation 72 PubMed, HPRD
Carboxylation 75 PubMed, HPRD
Glycosylation 121 PubMed, HPRD
Glycosylation 143 PubMed, HPRD
N-linked 121 PubMed, HPRD
N-linked 143 PubMed, HPRD
N-linked 416 PubMed, HPRD
Proteolytic Cleavage 198 PubMed, HPRD
Proteolytic Cleavage 314 PubMed, HPRD
Proteolytic Cleavage 327 PubMed, HPRD
Proteolytic Cleavage 436 PubMed, HPRD

Protein: THBD

PTMResidueReference
3-hydroxyasparagine 342 HPRD
O-linked 490 PubMed, HPRD
O-linked 492 PubMed, HPRD
Localisation

Protein: F2

LocalisationReference
Secreted HPRD

Protein: THBD

LocalisationReference
Plasma membrane HPRD
Secreted HPRD
Transitive Score

The common interactors between F2 and THBD that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between F2 andTHBD. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , F2 has 909 interactors and THBD has 1039 interactors of which there are 624 common interactors.

Common InteractorName of Common InteractorScore for F2-Interactor (?)Score for THBD-Interactor (?)
F10 F10: Coagulation factor X precursor 2.47E3 0.130
PLG PLG: Plasminogen precursor 826.00 0.109
F9 F9: Coagulation factor IX precursor 386.00 0.161
SERPINB1 SERPINB1, ELANH2, MNEI, PI2: Leukocyte elastase inhibitor 370.00 0.123
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 50.50 0.109
SERPING1 SERPING1, C1IN, C1NH: Plasma protease C1 inhibitor precursor 50.50 0.152
ITIH4 ITIH4, IHRP, PRO1851, ITIHL1, PK120: Inter-alpha-trypsin inhibitor heavy chain H 50.50 0.062
SERPINA4 SERPINA4, KST, PI4: Kallistatin precursor 50.50 0.109
SERPINF2 SERPINF2, AAP, PLI: Alpha-2-antiplasmin precursor 50.50 0.109
SERPIND1 SERPIND1, HCF2: Heparin cofactor 2 precursor 50.50 0.109
SERPINC1 SERPINC1, AT3, PRO0309: Antithrombin-III precursor 45.20 0.109
SERPINA6 SERPINA6, CBG: Corticosteroid-binding globulin precursor 16.80 0.109
SERPINA1 SERPINA1, AAT, PRO0684, PI, PRO2209: Alpha-1-antitrypsin precursor 16.80 0.152
AGT AGT, SERPINA8: Angiotensinogen precursor 16.80 0.123
SERPINA10 SERPINA10, ZPI, UNQ707/PRO1358: Protein Z-dependent protease inhibitor precursor 7.89 0.109
IGFALS IGFALS, ALS: Insulin-like growth factor-binding protein complex acid labile chai 6.17 0.055
APCS APCS, PTX2: Serum amyloid P-component precursor 5.75 0.123
HGFAC HGFAC: Hepatocyte growth factor activator precursor 5.75 0.109
AMBP AMBP, HCP, ITIL: AMBP protein precursor [Contains: Alpha-1-microglobulin 5.75 0.109
C8A C8A: Complement component C8 alpha chain precursor 5.75 0.109
HPX HPX: Hemopexin precursor 5.75 0.109
HP HP: Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta c 5.75 0.123
F12 F12: Coagulation factor XII precursor 5.75 0.109
VTN VTN: Vitronectin precursor 5.75 0.123
PROC PROC: Vitamin K-dependent protein C precursor 5.15 0.115
C6 C6: Complement component C6 precursor 5.15 0.123
APOA2 APOA2: Apolipoprotein A-II precursor 5.03 0.123
ORM1 ORM1, AGP1: Alpha-1-acid glycoprotein 1 precursor 5.03 0.055
C8G C8G: Complement component C8 gamma chain precursor 5.03 0.055
APOA1 APOA1: Apolipoprotein A-I precursor 5.03 0.123
ORM2 ORM2, AGP2: Alpha-1-acid glycoprotein 2 precursor 5.03 0.055
F5 F5: Coagulation factor V precursor 4.77 0.123
SERPINA3 N/A 4.77 0.123
SERPINF1 SERPINF1, PEDF: Pigment epithelium-derived factor precursor 3.85 0.152
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 3.45 0.429
ASGR2 ASGR2: Asialoglycoprotein receptor 2 3.16 0.109
SERPINA7 SERPINA7, TBG: Thyroxine-binding globulin precursor 2.84 0.123
HPN HPN, TMPRSS1: Serine protease hepsin 2.83 0.123
CFB CFB, BF, BFD: Complement factor B precursor 1.91 0.152
C4BPB C4BPB: C4b-binding protein beta chain precursor 1.91 0.109
C3 1.91 0.152
APOH APOH, B2G1: Beta-2-glycoprotein 1 precursor 1.91 0.109
C4BPA C4BPA, C4BP: C4b-binding protein alpha chain precursor 1.91 0.191
C2 C2: Complement C2 precursor 1.91 0.152
CP CP: Ceruloplasmin precursor 1.76 0.109
C8B C8B: Complement component C8 beta chain precursor 1.71 0.109
ALB ALB: Uncharacterized protein ALB 1.67 0.152
ANPEP ANPEP, APN, CD13, PEPN: Aminopeptidase N 1.60 0.051
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 1.53 0.165
SERPINA5 SERPINA5, PCI, PLANH3, PROCI: Plasma serine protease inhibitor precursor 1.41 0.109
SERPINB4 SERPINB3, SCCA, SCCA1: Serpin B3 1.14 0.123
ASGR1 ASGR1: Asialoglycoprotein receptor 1 1.07 0.0416
SERPINB13 SERPINB13, PI13: Serpin B13 1.02 0.109
F8 F8, F8C: Coagulation factor VIII precursor 1.00 0.123
SLC14A2 SLC14A2, HUT2, UT2: Urea transporter, kidney 1.00 0.109
SERPINI1 SERPINI1, PI12: Neuroserpin precursor 0.902 0.110
SERPINE1 SERPINE1, PAI1, PLANH1: Plasminogen activator inhibitor 1 precursor 0.902 0.152
NEO1 NEO1, NGN: Neogenin precursor 0.902 0.123
APOE APOE: Apolipoprotein E precursor 0.785 0.109
AFM AFM, ALB2, ALBA: Afamin precursor 0.785 0.109
APOM APOM, G3A, HSPC336, NG20: Apolipoprotein M 0.785 0.055
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.770 0.037
LCAT LCAT: Phosphatidylcholine-sterol acyltransferase precursor 0.708 0.045
LMAN2 LMAN2, C5orf8: Vesicular integral-membrane protein VIP36 precursor 0.594 0.0794
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.575 0.109
PTGS1 PTGS1, COX1: Prostaglandin G/H synthase 1 precursor 0.575 0.0688
CDO1 CDO1: Cysteine dioxygenase type 1 0.558 0.029
C1R C1R: Complement C1r subcomponent precursor 0.543 0.191
CFHR2 CFHR2, CFHL2, FHR2, HFL3: Complement factor H-related protein 2 precursor 0.543 0.123
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.543 0.161
LPA LPA: Apolipoprotein(a) precursor 0.486 0.123
PCOLCE PCOLCE, PCPE1: Procollagen C-endopeptidase enhancer 1 precursor 0.438 0.152
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.393 0.130
C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 0.393 0.123
FGB FGB: Fibrinogen beta chain precursor [Contains: Fibrinopeptide B] 0.393 0.109
ENPEP ENPEP: Glutamyl aminopeptidase 0.338 0.051
PCSK2 PCSK2, NEC2: Neuroendocrine convertase 2 precursor 0.338 0.041
CFH CFH, HF, HF1, HF2: Complement factor H precursor 0.324 0.152
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.318 0.029
CCL14 CCL14, NCC2, SCYA14: Small-inducible cytokine A14 precursor 0.318 0.251
CETP CETP: Cholesteryl ester transfer protein precursor 0.283 0.026
C1S C1S: Complement C1s subcomponent precursor 0.265 0.152
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.265 0.191
SHBG SHBG: Sex hormone-binding globulin precursor 0.265 0.123
A2M A2M, FWP007: Alpha-2-macroglobulin precursor 0.265 0.210
SERPINH1 SERPINH1, CBP1, PIG14, CBP2, HSP47, SERPINH2: Serpin H1 precursor 0.265 0.027
CPXM2 CPXM2, UNQ676/PRO1310: Carboxypeptidase-like protein X2 precursor 0.265 0.027
SERPINA12 SERPINA12: Serpin A12 precursor 0.265 0.027
SERPINA11 SERPINA11: Serpin A11 precursor 0.265 0.027
HEPH HEPH, KIAA0698, UNQ2562/PRO6242: Hephaestin precursor 0.265 0.027
CPXM CPXM1, CPX1, UNQ3015/PRO9782, CPXM: Probable carboxypeptidase X1 precursor 0.265 0.027
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.241 0.062
CCL1 CCL1, SCYA1: Small-inducible cytokine A1 precursor 0.241 0.152
SERPINI2 SERPINI2, MEPI, PI14: Serpin I2 precursor 0.237 0.027
CNTNAP1 CNTNAP1, CASPR, NRXN4: Contactin-associated protein 1 precursor 0.237 0.027
SERPINB12 SERPINB12: Serpin B12 0.237 0.027
SERPINB8 SERPINB8, PI8: Serpin B8 0.237 0.027
CNTNAP4 CASPR4: Cell recognition protein CASPR4 0.237 0.027
TFF2 TFF2, SML1: Trefoil factor 2 precursor 0.232 0.026
NRP2 NRP2, VEGF165R2: Neuropilin-2 precursor 0.217 0.027
DCBLD1 DCBLD1: Discoidin, CUB and LCCL domain-containing protein 1 precursor 0.217 0.027
FN1 N/A 0.209 0.165
THPO THPO, MGDF: Thrombopoietin precursor 0.209 0.028
CSF3 CSF3, GCSF: Granulocyte colony-stimulating factor precursor 0.209 0.028
KITLG KITLG, MGF, SCF: Kit ligand precursor 0.209 0.028
CCL26 CCL26, SCYA26, UNQ216/PRO242: Small-inducible cytokine A26 precursor 0.209 0.165
DCN DCN: Decorin precursor 0.209 0.083
IFNG IFNG: Interferon gamma precursor 0.209 0.083
C1QC C1QC, C1QG: Complement C1q subcomponent subunit C precursor 0.209 0.174
CCL15 CCL15, MIP5, NCC3, SCYA15: Small-inducible cytokine A15 precursor 0.209 0.165
IL4 IL4: Interleukin-4 precursor 0.209 0.028
OPTC OPTC, OPT: Opticin precursor 0.209 0.083
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.209 0.083
LOC643930 CCL3L1, D17S1718, G0S19-2, SCYA3L1: Small-inducible cytokine A3-like 1 precursor 0.209 0.165
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.209 0.083
CXCL9 CXCL9, CMK, MIG, SCYB9: Small-inducible cytokine B9 precursor 0.201 0.191
PZP PZP: Pregnancy zone protein precursor 0.201 0.096
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.195 0.027
C1QA C1QA: Complement C1q subcomponent subunit A precursor 0.192 0.324
DSPG3 EPYC, DSPG3, PGLB: Epiphycan precursor 0.192 0.077
BGN BGN: Biglycan precursor 0.192 0.210
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.187 0.165
FGA N/A 0.180 0.109
CFHR1 CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2: Complement factor H-relate 0.174 0.165
F11 F11: Coagulation factor XI precursor 0.174 0.165
C4A C4A: Complement C4-A precursor 0.174 0.165
TFPI TFPI, LACI, TFPI1: Tissue factor pathway inhibitor precursor 0.174 0.165
BGLAP BGLAP: Osteocalcin precursor 0.174 0.174
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.174 0.165
GRN GRN: Granulins precursor 0.174 0.028
AEBP1 CDNA FLJ45634 fis, clone CHONS2002829, moderately similar to Homo sapiens adipoc 0.174 0.0308
CD46 N/A 0.165 0.056
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.161 0.251
CFI CFI, IF: Complement factor I precursor 0.161 0.152
F13B F13B: Coagulation factor XIII B chain precursor 0.161 0.109
CMA1 CMA1, CYH, CYM: Chymase precursor 0.161 0.123
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.161 0.191
ANGPTL3 ANGPTL3, ANGPT5, UNQ153/PRO179: Angiopoietin-related protein 3 precursor 0.161 0.109
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.156 0.165
PLAT PLAT: Tissue-type plasminogen activator precursor 0.156 0.165
COL18A1 N/A 0.156 0.165
CPB2 CPB2: Carboxypeptidase B2 precursor 0.156 0.028
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.156 0.174
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.156 0.165
BMP1 N/A 0.156 0.165
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.156 0.165
F7 F7: Coagulation factor VII precursor 0.156 0.174
KLK3 KLK3, APS: Prostate-specific antigen precursor 0.156 0.165
SPOCK1 SPOCK1, SPOCK, TIC1, TICN1: Testican-1 precursor 0.156 0.165
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.156 0.165
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.156 0.165
SERPINB2 SERPINB2, PAI2, PLANH2: Plasminogen activator inhibitor 2 precursor 0.156 0.0308
CCL8 CCL8, MCP2, SCYA10, SCYA8: Small-inducible cytokine A8 precursor 0.156 0.123
IL2 IL2: Interleukin 2 0.156 0.055
CSF2 CSF2, GMCSF: Granulocyte-macrophage colony-stimulating factor precursor 0.156 0.062
IL5 IL5: Interleukin-5 precursor 0.156 0.055
CCL13 CCL13, MCP4, NCC1, SCYA13: Small-inducible cytokine A13 precursor 0.156 0.191
EPO EPO: Erythropoietin precursor 0.156 0.049
ASPN ASPN: ASPN protein 0.156 0.077
MMRN2 MMRN2, EMILIN3: Multimerin-2 precursor 0.152 0.165
GRP Gastrin-releasing peptide 0.152 0.028
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.152 0.165
PTHLH N/A 0.152 0.028
GUCA2A GUCA2A, GUCA2: Guanylin precursor 0.152 0.028
CCL14 N/A 0.152 0.028
NULL A1BG: Alpha-1B-glycoprotein precursor 0.152 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.152 0.165
CST4 CST4: Cystatin-S precursor 0.152 0.028
PCSK6 N/A 0.152 0.028
ACCN3 ACCN3, ASIC3, SLNAC1, TNAC1: Amiloride-sensitive cation channel 3 0.152 0.028
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.152 0.165
LECT1 LECT1, CHMI: Chondromodulin-1 precursor 0.152 0.028
NOG NOG: Noggin precursor 0.152 0.028
PLAU Plasminogen activator, urokinase 0.152 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.152 0.028
PLTP PLTP: Phospholipid transfer protein precursor 0.152 0.028
CSF1 CSF1: Macrophage colony-stimulating factor 1 precursor 0.152 0.028
GHRL GHRL, MTLRP, UNQ524/PRO1066: Appetite-regulating hormone precursor 0.152 0.028
ECM1 ECM1: Extracellular matrix protein 1 precursor 0.152 0.165
SDC1 SDC1, SDC: Syndecan-1 precursor 0.145 0.0425
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.144 0.191
IL22 IL22, ILTIF, UNQ3099/PRO10096: Interleukin-22 precursor 0.140 0.026
WNT2B WNT2B, WNT13: Protein Wnt-2b precursor 0.140 0.123
IGF2 IGF2, PP1446: Insulin-like growth factor II precursor 0.140 0.026
GAST GAST, GAS: Gastrin precursor [Contains: Gastrin-71 0.140 0.123
GAA GAA: Uncharacterized protein GAA 0.140 0.052
AFP AFP, HPAFP: Alpha-fetoprotein precursor 0.140 0.109
AGRP AGRP, AGRT, ART: Agouti-related protein precursor 0.140 0.026
XCL1 XCL1, LTN, SCYC1: Lymphotactin precursor 0.137 0.109
KERA KERA: Keratocan precursor 0.137 0.062
COL17A1 COL17A1, BP180, BPAG2: Collagen alpha-1(XVII) chain 0.137 0.152
CSH2 GH1: Somatotropin precursor 0.137 0.026
CCL21 CCL21, SCYA21, UNQ784/PRO1600: Small-inducible cytokine A21 precursor 0.137 0.191
COL1A1 COL1A1: Collagen alpha-1(I) chain precursor 0.137 0.191
IL6 IL6, IFNB2: Interleukin-6 precursor 0.137 0.062
CCL24 CCL24, MPIF2, SCYA24: Small-inducible cytokine A24 precursor 0.137 0.191
CCL11 CCL11, SCYA11: Eotaxin precursor 0.137 0.123
CCL4 CCL4, CCL4L, LAG1, MIP1B, SCYA4, SCYA4L: Small-inducible cytokine A4 precursor 0.137 0.109
LIF LIF, HILDA: Leukemia inhibitory factor precursor 0.137 0.055
COL3A1 COL3A1: Collagen alpha-1(III) chain precursor 0.137 0.191
ADIPOQ ADIPOQ, ACDC, ACRP30, APM1, GBP28: Adiponectin precursor 0.137 0.115
IL3 IL3: Interleukin-3 precursor 0.137 0.055
LUM LUM, LDC: Lumican precursor 0.137 0.127
CCL2 CCL2, MCP1, SCYA2: Small-inducible cytokine A2 precursor 0.137 0.123
OSM OSM: Oncostatin-M precursor 0.137 0.049
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.137 0.109
CCL5 CCL5, D17S136E, SCYA5: Small-inducible cytokine A5 precursor 0.137 0.109
PRL PRL: Prolactin precursor 0.137 0.055
COL5A2 N/A 0.137 0.191
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.137 0.109
VNN1 VNN1: Pantetheinase precursor 0.137 0.028
CA11 CA11, CARP2, UNQ211/PRO237: Carbonic anhydrase-related protein 11 precursor 0.137 0.028
CNTN1 CNTN1: Contactin-1 precursor 0.137 0.165
LOC641705 AMY2A: Pancreatic alpha-amylase precursor 0.137 0.028
ITM2C ITM2C, BRI3, hucep-14, NPD018, PSEC0047: Integral membrane protein 2C 0.137 0.028
CNTN4 CNTN4: Contactin-4 precursor 0.137 0.165
SDC4 SDC4: Syndecan-4 precursor 0.130 0.032
CXCL10 CXCL10, INP10, SCYB10: Small-inducible cytokine B10 precursor 0.130 0.123
EDN3 EDN3: Endothelin-3 precursor 0.130 0.026
SLPI SLPI, WAP4, WFDC4: Antileukoproteinase precursor 0.130 0.032
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.130 0.201
CXCL11 CXCL11, ITAC, SCYB11, SCYB9B: Small-inducible cytokine B11 precursor 0.130 0.123
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.130 0.307
CLEC3B CLEC3B, TNA: Tetranectin precursor 0.130 0.416
PRSS22 PRSS22, BSSP4, SP001LA, PRSS26, UNQ302/PRO343: Brain-specific serine protease 4 0.130 0.152
CXCL12 Stromal cell-derived factor 1 delta 0.130 0.123
PF4V1 PF4V1, SCYB4V1: Platelet factor 4 variant precursor 0.123 0.152
VWF VWF, F8VWF: von Willebrand factor precursor 0.123 0.515
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.123 0.110
TIMP1 TIMP1, CLGI, TIMP: Metalloproteinase inhibitor 1 precursor 0.117 0.096
MMP11 MMP11, STMY3: Stromelysin-3 precursor 0.117 0.251
PRG4 PRG4, MSF, SZP: Proteoglycan-4 precursor 0.117 0.109
MMP8 CLG1, MMP8: Neutrophil collagenase precursor 0.117 0.109
ELA3B ELA3B: Elastase-3B precursor 0.115 0.109
PRG2 PRG2, MBP: Bone marrow proteoglycan precursor 0.115 0.191
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.115 0.161
PF4 PF4, CXCL4, SCYB4: Platelet factor 4 precursor 0.115 0.152
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.115 0.251
CXCL5 CXCL5, ENA78, SCYB5: Small-inducible cytokine B5 precursor 0.115 0.123
SPINT2 SPINT2, HAI2, KOP: Kunitz-type protease inhibitor 2 precursor 0.115 0.191
TG TG: Thyroglobulin precursor 0.115 0.152
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.115 0.191
GZMB Endogenous granzyme B 0.115 0.123
MMP9 MMP9, CLG4B: Matrix metalloproteinase-9 precursor 0.115 0.123
TACSTD1 TACSTD1, GA733-2, M1S2, M4S1, MIC18, TROP1: Tumor-associated calcium signal tran 0.115 0.152
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.115 0.152
CFP CFP, PFC: Properdin precursor 0.115 0.123
NOTCH4 N/A 0.115 0.251
ELA2 ELA2: Leukocyte elastase precursor 0.115 0.109
REG1B REG1B, REGL: Lithostathine 1 beta precursor 0.115 0.109
CXCL1 CXCL1, GRO, GRO1, GROA, MGSA, SCYB1: Growth-regulated protein alpha precursor 0.115 0.123
SPINK1 SPINK1, PSTI: Pancreatic secretory trypsin inhibitor precursor 0.115 0.055
CSPG2 N/A 0.115 0.123
MUC2 MUC2, SMUC: Mucin-2 precursor 0.115 0.123
AZU1 AZU1: Azurocidin precursor 0.115 0.109
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.115 0.191
CCL22 CCL22, A-152E5.1, MDC, SCYA22: Small-inducible cytokine A22 precursor 0.115 0.109
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.115 0.062
LGALS3 LGALS3, MAC2: Galectin-3 0.115 0.152
COL5A1 N/A 0.115 0.201
SFTPA2 SFTPA2, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A2 precursor 0.115 0.416
EDN1 EDN1: Endothelin-1 precursor 0.115 0.070
MMP13 MMP13: Collagenase 3 precursor 0.115 0.109
CTSG CTSG: Cathepsin G precursor 0.115 0.109
IL8 IL8: Interleukin-8 precursor 0.115 0.123
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.115 0.251
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.115 0.251
REG1B REG1A, PSPS, REG: Lithostathine 1 alpha precursor 0.115 0.109
REG3A REG3A, HIP, PAP, PAP1: Regenerating islet-derived protein 3 alpha precursor 0.115 0.109
COL15A1 COL15A1: Collagen alpha-1(XV) chain precursor [Contains: Endostatin 0.115 0.251
UMOD UMOD: Uromodulin precursor 0.115 0.109
IL2RA IL2RA: Interleukin-2 receptor alpha chain precursor 0.115 0.123
PPBP PPBP, CTAP3, SCYB7, TGB1, THBGB1: Platelet basic protein precursor 0.115 0.152
PRTN3 PRTN3, MBN: Myeloblastin precursor 0.115 0.109
PRSS1 PRSS1, TRP1, TRY1, TRYP1: Trypsin-1 precursor 0.115 0.109
AOC3 AOC3, VAP1: Membrane copper amine oxidase 0.114 0.032
IFNA14 IFNA14: Interferon alpha-14 precursor 0.114 0.062
LIPG LIPG, UNQ387/PRO719: Endothelial lipase precursor 0.114 0.191
IFNB1 IFNB1, IFB, IFNB: Interferon beta precursor 0.114 0.062
TSHB TSHB: Thyrotropin subunit beta precursor 0.114 0.109
PSAP PSAP, GLBA, SAP1: Proactivator polypeptide precursor [Contains: Saposin-A 0.114 0.026
FSHB FSHB: Follitropin subunit beta precursor 0.114 0.109
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.114 0.123
LGALS3BP LGALS3BP, M2BP: Galectin-3-binding protein precursor 0.114 0.251
HLA-DQB2 HLA-DQB2, DASS-256O6.1-002, XXbac-BCX231H22.1-002, XXbac-BPG3L13.3-002: Major hi 0.114 0.026
TFF1 TFF1, BCEI, PS2: Trefoil factor 1 precursor 0.114 0.026
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.114 0.123
SFTPB SFTPB, SFTP3: Pulmonary surfactant-associated protein B precursor 0.114 0.087
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.111 0.085
LGALS1 LGALS1: Galectin-1 0.109 0.152
IL15RA IL15RA: Interleukin-15 receptor alpha chain precursor 0.109 0.064
MGP MGP, MGLAP, GIG36: Matrix Gla protein precursor 0.109 0.064
CPD CPD: Carboxypeptidase D precursor 0.103 0.026
LAMA2 LAMA2: Uncharacterized protein LAMA2 0.103 0.152
KLK6 KLK6, PRSS18, PRSS9: Kallikrein-6 precursor 0.103 0.098
THBS1 THBS1, TSP, TSP1: Thrombospondin-1 precursor 0.103 0.191
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.103 0.191
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.103 0.109
CPA2 CPA2: Carboxypeptidase A2 precursor 0.103 0.055
MMP7 MMP7, MPSL1, PUMP1: Matrilysin precursor 0.103 0.152
KLK1 KLK1: Kallikrein-1 precursor 0.103 0.109
MMP1 MMP1, CLG: Interstitial collagenase precursor 0.103 0.123
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.103 0.055
SFTPD SFTPD, PSPD, SFTP4: Pulmonary surfactant-associated protein D precursor 0.103 0.307
C7 C7: Complement component C7 precursor 0.103 0.191
SPON1 SPON1, KIAA0762, VSGP: Spondin-1 precursor 0.103 0.123
CTGF CTGF, CCN2, HCS24: Connective tissue growth factor precursor 0.103 0.191
MMP2 MMP2, CLG4A: 72 kDa type IV collagenase precursor 0.103 0.152
MFAP4 MFAP4: Microfibril-associated glycoprotein 4 precursor 0.103 0.416
FGL2 FGL2: Fibroleukin precursor 0.103 0.123
TNC TNC, HXB: Tenascin precursor 0.103 0.191
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.103 0.191
CPM CPM: Carboxypeptidase M precursor 0.103 0.0425
CPB1 CPB1, CPB, PCPB: Carboxypeptidase B precursor 0.103 0.055
COL4A1 N/A 0.103 0.307
SPARC SPARC, ON: SPARC precursor 0.103 0.191
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.103 0.152
PLA2G7 PAFAH, PLA2G7: Platelet-activating factor acetylhydrolase precursor 0.102 0.152
LIPF LIPF: Gastric triacylglycerol lipase precursor 0.102 0.152
CHI3L1 CHI3L1: Chitinase-3-like protein 1 precursor 0.102 0.026
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.100 0.123
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.100 0.110
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.100 0.055
MFAP2 MFAP2, MAGP1: Microfibrillar-associated protein 2 precursor 0.100 0.251
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.100 0.152
PAPPA PAPPA, RP11-45A16.1-001: Pregnancy-associated plasma protein A, pappalysin 1 (Fr 0.100 0.0425
RNASE1 RNASE1, RIB1, RNS1: Ribonuclease pancreatic precursor 0.100 0.032
CGA CGA: Glycoprotein hormones alpha chain precursor 0.100 0.077
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.100 0.152
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.100 0.127
IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 0.100 0.026
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.100 0.123
IFNW1 IFNW1: Interferon omega-1 precursor 0.100 0.055
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.100 0.152
LCN2 LCN2, HNL, NGAL: Neutrophil gelatinase-associated lipocalin precursor 0.100 0.062
NDP NDP: Norrin precursor 0.100 0.055
LOX LOX: Protein-lysine 6-oxidase precursor 0.100 0.026
PTGDS PTGDS, PDS: Prostaglandin-H2 D-isomerase precursor 0.100 0.055
PAEP PAEP: Glycodelin precursor 0.100 0.062
LHB LHB: Lutropin subunit beta precursor 0.100 0.109
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.100 0.055
CCK CCK: Cholecystokinins precursor 0.100 0.098
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.100 0.049
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.100 0.251
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.100 0.123
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.100 0.123
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.100 0.152
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.100 0.123
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.100 0.123
CEL CEL, RP11-326L24.2-001: Carboxyl ester lipase 0.100 0.109
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.100 0.191
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.099 0.191
COL16A1 COL16A1: Collagen alpha-1(XVI) chain precursor 0.098 0.109
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.098 0.056
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.097 0.0416
ALK ALK: ALK tyrosine kinase receptor precursor 0.097 0.0416
TMPRSS9 N/A 0.096 0.165
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.096 0.165
DLK1 DLK1, DLK: Delta-like protein precursor 0.096 0.165
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.096 0.165
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.096 0.165
THOP1 THOP1: Thimet oligopeptidase 0.094 0.026
SLIT2 SLIT2, SLIL3: Slit homolog 2 protein precursor 0.093 0.251
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.090 0.064
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.0898 0.123
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.0898 0.034
FIGF FIGF, VEGFD: Vascular endothelial growth factor D precursor 0.0898 0.307
VNN2 VNN2: Vascular non-inflammatory molecule 2 precursor 0.0898 0.026
WNT3 WNT3, INT4: Proto-oncogene protein Wnt-3 precursor 0.0898 0.152
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.0898 0.056
FGF9 FGF9: Glia-activating factor precursor 0.0898 0.056
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.0898 0.152
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.0898 0.077
PNLIP PNLIP: Pancreatic triacylglycerol lipase precursor 0.0898 0.109
APOD APOD: Apolipoprotein D precursor 0.0898 0.055
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.088 0.307
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.087 0.028
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.087 0.165
TBXA2R TBXA2R: Thromboxane A2 receptor 0.087 0.028
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.087 0.028
DRD2 DRD2: D(2) dopamine receptor 0.087 0.028
C3AR1 C3AR1, AZ3B, C3R1, HNFAG09: C3a anaphylatoxin chemotactic receptor 0.087 0.028
EDA N/A 0.087 0.165
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.087 0.028
JAG2 JAG2: Jagged-2 precursor 0.086 0.165
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.086 0.165
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.086 0.165
ATRN N/A 0.086 0.165
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.086 0.165
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.081 0.307
SELE SELE, ELAM1: E-selectin precursor 0.081 0.152
GP1BA N/A 0.080 0.062
MEP1B MEP1B: Meprin A subunit beta precursor 0.079 0.152
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.078 0.165
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.078 0.165
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.073 0.037
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.073 0.0416
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.073 0.051
TACR2 TACR2, NK2R, NKNAR, TAC2R: Substance-K receptor 0.072 0.026
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.072 0.037
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.072 0.037
MARCO MARCO, SCARA2: Macrophage receptor MARCO 0.071 0.128
KEL KEL: Kell blood group glycoprotein 0.071 0.098
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.071 0.098
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.071 0.152
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.071 0.152
SORL1 SORL1: Sortilin-related receptor precursor 0.071 0.109
F2RL1 F2RL1, GPR11, PAR2: Proteinase-activated receptor 2 precursor 0.071 0.026
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.065 0.123
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.065 0.109
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.065 0.152
EDG1 EDG1: Sphingosine 1-phosphate receptor Edg-1 0.065 0.0425
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.064 0.123
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.064 0.064
ITGB7 ITGB7: Integrin beta-7 precursor 0.064 0.033
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.064 0.037
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.064 0.051
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.064 0.152
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.064 0.123
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.064 0.123
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.064 0.152
IGF2R IGF2R, MPRI: Cation-independent mannose-6-phosphate receptor precursor 0.064 0.039
F2R F2R, CF2R, PAR1, TR: Proteinase-activated receptor 1 precursor 0.063 0.026
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.063 0.152
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.063 0.109
CD69 CD69: Early activation antigen CD69 0.063 0.098
SFRP1 CDNA FLJ45402 fis, clone BRHIP3029409, moderately similar to Homo sapiens secret 0.063 0.062
AREG AREG, SDGF: Amphiregulin precursor 0.063 0.123
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.063 0.123
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.063 0.109
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.063 0.098
MME MME, EPN: Neprilysin 0.063 0.109
EGF EGF: Pro-epidermal growth factor precursor 0.063 0.123
ITGB4 N/A 0.063 0.152
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, testis-specific isoform precursor 0.063 0.191
F3 F3: Tissue factor precursor 0.063 0.077
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.062 0.044
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.060 0.051
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.060 0.064
DCC DCC: Netrin receptor DCC precursor 0.058 0.109
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.058 0.109
GP5 GP5: Platelet glycoprotein V precursor 0.058 0.055
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.057 0.110
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.057 0.098
C5AR1 C5AR1, C5AR, C5R1: C5a anaphylatoxin chemotactic receptor 0.057 0.026
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.057 0.152
GP1BB GP1BB: Platelet glycoprotein Ib beta chain precursor 0.057 0.049
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.057 0.096
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.057 0.098
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.057 0.062
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.056 0.191
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.056 0.123
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.056 0.191
LDLR LDLR: Low-density lipoprotein receptor precursor 0.056 0.123
MEP1A MEP1A: Meprin A subunit alpha precursor 0.056 0.109
CSPG4 CSPG4, MCSP: Chondroitin sulfate proteoglycan 4 precursor 0.056 0.251
CRLF3 N/A 0.055 0.055
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.052 0.077
ITGAE ITGAE: Integrin alpha-E precursor 0.052 0.109
COL11A1 COL11A1, COLL6: Collagen alpha-1(XI) chain precursor 0.051 0.051
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.051 0.026
ITGA2B ITGA2B, GP2B, ITGAB: Integrin alpha-IIb precursor 0.051 0.109
PTPRZ1 N/A 0.051 0.056
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.051 0.062
ITGA3 ITGA3, MSK18: Integrin alpha-3 precursor 0.051 0.251
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.051 0.062
TLR4 TLR4: Toll-like receptor 4 precursor 0.051 0.077
TSHR N/A 0.051 0.077
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.051 0.307
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.051 0.251
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.050 0.056
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.049 0.030
ITGAV ITGAV, MSK8, VNRA: Integrin alpha-V precursor 0.0462 0.123
LMAN1 LMAN1, ERGIC53, F5F8D: Protein ERGIC-53 precursor 0.046 0.045
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.044 0.056
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.041 0.064
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.041 0.072
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.041 0.029
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.040 0.085
SELP SELP, GMRP, GRMP: P-selectin precursor 0.039 0.0308
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.038 0.109
ARMET ARMET, ARP: Protein ARMET precursor 0.038 0.026
CD55 CD55, CR, DAF: Complement decay-accelerating factor precursor 0.037 0.085
PKD1 PKD1: Polycystin-1 precursor 0.0338 0.030
CDH6 CDH6: Cadherin-6 precursor 0.0333 0.028
CSF3R N/A 0.0333 0.028
ITGB1 N/A 0.0333 0.028
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.0333 0.165
MUCDHL MUPCDH, MUCDHL, UNQ2781/PRO7168: Mucin and cadherin-like protein precursor 0.0333 0.028
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.0333 0.028
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.0333 0.165
PILRA PILRA: Paired immunoglobulin-like type 2 receptor alpha precursor 0.0333 0.028
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.0333 0.165
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.0333 0.165
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.0333 0.083
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.0333 0.165
SNAP25 N/A 0.0333 0.028
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.0333 0.165
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.0333 0.165
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.0333 0.165
GP9 GP9: Platelet glycoprotein IX precursor 0.032 0.096
PRSS8 PRSS8: Prostasin precursor 0.0308 0.050
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.031 0.109
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.031 0.191
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.031 0.152
PVR PVR, PVS: Poliovirus receptor precursor 0.031 0.191
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.030 0.049
C2orf7 PAP21, C2orf7, UNQ833/PRO1760: Protease-associated domain-containing protein of 0.030 0.028
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.030 0.165
SLC7A3 SLC7A3, ATRC3, CAT3: Cationic amino acid transporter 3 0.030 0.028
GPC3 GPC3, OCI5: Glypican-3 precursor 0.030 0.028
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.030 0.083
ATP1B1 N/A 0.030 0.028
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.030 0.028
BSG N/A 0.030 0.165
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.030 0.028
GPC2 GPC2: Glypican-2 precursor 0.030 0.028
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.030 0.0416
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.029 0.064
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.029 0.051
NULL Ig kappa chain V-I region CAR 0.029 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.029 0.051
OLFM1 OLFM1, NOE1, NOEL1: Noelin precursor 0.029 0.051
NULL Ig lambda chain V-II region NEI 0.029 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.029 0.051
NULL Ig lambda chain V-I region EPS 0.029 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.029 0.051
NCAM1 N/A 0.029 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.029 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.029 0.051
NULL Ig heavy chain V-III region WEA 0.029 0.051
IGHG1 N/A 0.029 0.051
NULL Ig heavy chain V-III region BUR 0.029 0.051
FAP FAP: Seprase 0.029 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.029 0.051
IGHE IGHE: Ig epsilon chain C region 0.029 0.051
IGHG3 N/A 0.029 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.029 0.051
IGHD N/A 0.029 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.029 0.051
IGHA1 N/A 0.029 0.051
HLA-A N/A 0.029 0.051
IGHM N/A 0.029 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.029 0.051
NULL Ig kappa chain V region EV15 precursor 0.029 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.029 0.051
VEGF vascular endothelial growth factor A isoform a precursor 0.029 0.051
LOC649805 Ig heavy chain V-II region COR 0.029 0.051
C1QTNF4 C1QTNF4, CTRP4: Complement C1q tumor necrosis factor-related protein 4 precursor 0.028 0.056
LAMB2 LAMB2, LAMS: Laminin subunit beta-2 precursor 0.028 0.050
CD207 CD207, CLEC4K: C-type lectin domain family 4 member K 0.027 0.026
PLAU PLAU: Urokinase-type plasminogen activator precursor 0.027 0.051
ITGB1 ITGB1, FNRB, MDF2, MSK12: Integrin beta-1 precursor 0.027 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.027 0.027
KLKB1 N/A 0.027 0.051
CD74 CD74, DHLAG: HLA class II histocompatibility antigen gamma chain 0.027 0.051
COL4A2 COL4A2: Collagen alpha-2(IV) chain precursor [Contains: Canstatin] 0.027 0.051
MMRN1 MMRN1, ECM, EMILIN4, MMRN: Multimerin-1 precursor 0.027 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.027 0.051
C4B C4B: Complement C4-B precursor 0.027 0.051
CSPG5 N/A 0.027 0.051
SPOCK3 SPOCK3, TICN3, UNQ409/PRO771: Testican-3 precursor 0.027 0.051
LTBP1 LTBP1: Latent-transforming growth factor beta-binding protein, isoform 1S precur 0.027 0.051
SPARCL1 SPARCL1: SPARC-like protein 1 precursor 0.027 0.051
ELTD1 ELTD1, RP11-143H12.1-002: EGF, latrophilin and seven transmembrane domain contai 0.027 0.051
C5 C5: Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 a 0.027 0.051
FN1 FN1, FN: Fibronectin precursor 0.027 0.051
MST1 MST1, D3F15S2, DNF15S2, HGFL: Hepatocyte growth factor-like protein precursor 0.027 0.051
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.027 0.096
CFC1 CFC1: Cryptic protein precursor 0.027 0.027
THSD3 N/A 0.027 0.027
CXCL16 CXCL16, SCYB16, UNQ2759/PRO6714, SRPSOX: Small-inducible cytokine B16 precursor 0.027 0.027
REG4 REG4, GISP, RELP: Regenerating islet-derived protein 4 precursor 0.027 0.027
NTN4 NTN4: Netrin-4 precursor 0.027 0.027
UNQ739 VWC2, UNQ739, hCG_2045125, tcag7.1302: von Willebrand factor C domain-containing 0.027 0.027
NETO1 N/A 0.027 0.027
ADAMTS10 ADAMTS10: ADAMTS-10 precursor 0.027 0.027
NELL2 NELL2, NRP2: Protein kinase C-binding protein NELL2 precursor 0.027 0.027
ELA2A ELA2A: Elastase-2A precursor 0.027 0.027
COL11A2 COL11A2: Collagen alpha-2(XI) chain precursor 0.027 0.027
TPSAB1 N/A 0.027 0.027
CILP2 CILP2: Cartilage intermediate layer protein 2 precursor 0.027 0.027
FSTL5 FSTL5, KIAA1263: Follistatin-related protein 5 precursor 0.027 0.027
ADAMTS17 ADAMTS17: ADAMTS-17 precursor 0.027 0.027
COX2 MT-CO2, COII, COXII, MTCO2: Cytochrome c oxidase subunit 2 0.027 0.027
PRSS36 PRSS36: Polyserase-2 precursor 0.027 0.027
ADAMTSL1 N/A 0.027 0.027
ADAMTS19 ADAMTS19: ADAMTS-19 precursor 0.027 0.027
CR1L complement component (3b/4b) receptor 1-like 0.027 0.027
HHIP HHIP, HIP, UNQ5825/PRO19644: Hedgehog-interacting protein precursor 0.027 0.027
PRRG4 PRRG4, TMG4: Transmembrane gamma-carboxyglutamic acid protein 4 precursor 0.027 0.027
KLK9 KLK9: Kallikrein-9 precursor 0.027 0.027
CFHR3 CFHR3, CFHL3, FHR3: Complement factor H-related protein 3 precursor 0.027 0.027
PRSS21 PRSS21, ESP1, UNQ266/PRO303, TEST1: Testisin precursor 0.027 0.027
ADAMTS18 ADAMTS18, ADAMTS21: ADAMTS-18 precursor 0.027 0.027
CLEC3A CLEC3A: C-type lectin domain family 3, member A 0.027 0.027
MASP2 MASP2: Mannan-binding lectin serine protease 2 precursor 0.027 0.027
CSPG3 CSPG3, NCAN, NEUR: Neurocan core protein precursor 0.027 0.027
PAPPA2 PAPPA2, PLAC3: Pappalysin-2 precursor 0.027 0.027
KLK12 KLK12, KLKL5, UNQ669/PRO1303: Kallikrein-12 precursor 0.027 0.027
CLEC14A CLEC14A, C14orf27, UNQ236/PRO269, EGFR5: C-type lectin domain family 14 member A 0.027 0.027
KREMEN2 KREMEN2, KRM2: Kremen protein 2 precursor 0.027 0.027
C21orf29 TSPEAR, C21orf29: Protein TSPEAR precursor 0.027 0.027
NTNG2 N/A 0.027 0.027
PRSS27 PRSS27, MPN, UNQ1884/PRO4327: Serine protease 27 precursor 0.027 0.027
MUC13 MUC13, DRCC1, UNQ6194/PRO20221, RECC: Mucin-13 precursor 0.027 0.027
WISP3 WISP3, CCN6, UNQ462/PRO790/PRO956: WNT1-inducible-signaling pathway protein 3 pr 0.027 0.027
GP2 GP2: Pancreatic secretory granule membrane major glycoprotein GP2 precursor 0.027 0.027
PLGLA1 PLGLA1, PLGP2: Plasminogen-related protein A precursor 0.027 0.027
ND4L MT-ND4L, MTND4L, NADH4L, ND4L: NADH-ubiquinone oxidoreductase chain 4L 0.027 0.027
REG3G REG3G, PAP1B, UNQ429/PRO162: Regenerating islet-derived protein 3 gamma precurso 0.027 0.027
ITLN1 ITLN1, INTL, UNQ640/PRO1270, ITLN, LFR: Intelectin-1 precursor 0.027 0.027
PRRG1 PRRG1, PRGP1, TMG1: Transmembrane gamma-carboxyglutamic acid protein 1 precursor 0.027 0.027
IFRD2 0.027 0.027
LAMC2 LAMC2, LAMB2T, LAMNB2: Laminin subunit gamma-2 precursor 0.027 0.027
WISP3 LIBC, WISP3, RP1-142L7.3-004, hCG_34804: Lost in inflammatory breast cancer tumo 0.027 0.027
ITLN2 ITLN2, UNQ2789/PRO7179: Intelectin-2 precursor 0.027 0.027
SCARF2 SCARF2, SREC2, SREPCR: Scavenger receptor class F member 2 precursor 0.027 0.027
PRRG2 PRRG2, PRGP2, TMG2: Transmembrane gamma-carboxyglutamic acid protein 2 precursor 0.027 0.027
DAG1 DAG1: Dystroglycan precursor 0.027 0.0955
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.026 0.051
KNG1 KNG1, BDK, KNG: Kininogen-1 precursor 0.026 0.029
FLT4 VEGFR3 long form 0.026 0.051
CES1 CES1, CES2, SES1: Liver carboxylesterase 1 precursor 0.026 0.051
0.572
Total Score 29.70