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Evidence of Interaction Between F2 and C6

The interaction score between F2 and C6 is 469.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between F2 and C6 = 0.90

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 0.082
Orthology
OrganismF2 OrthologueC6 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
fly Q9VBY4 0.121 Q9VI89 0.226

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in F2 and C6:
Domains in F2Domains in C6
IPR000001 Kringle
IPR001254 Peptidase S1, chymotrypsin
IPR001314 Peptidase S1A, chymotrypsin
IPR009003 Peptidase, trypsin-like serine and cysteine proteases
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region
IPR002383 Coagulation factor, Gla region
IPR003966 Peptidase S1A, prothrombin
IPR012051 Thrombin.
IPR006209 EGF-like domain
IPR002172 Low density lipoprotein-receptor, class A
IPR000436 Sushi domain/SCR domain/CCP module
IPR000884 Thrombospondin, type I
IPR001862 Membrane attack complex component/perforin/complement C9
IPR008085 Thrombospondin, subtype 1
IPR003884 Factor I membrane attack complex
IPR000742 EGF_2.
IPR011497 Prot_Inh_Kazal_2.
IPR013032 IPR006209.

The Chi square scores for co-occurrence of domains that are present in F2 and C6 are listed below.

Domain 1Domain 2Chi Square
IPR002383 Coagulation factor, Gla region IPR000742 EGF_2. 53.7358
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR000742 EGF_2. 50.727
IPR003966 Peptidase S1A, prothrombin IPR008085 Thrombospondin, subtype 1 49.8655
IPR001314 Peptidase S1A, chymotrypsin IPR013032 IPR006209. 43.7147
IPR001254 Peptidase S1, chymotrypsin IPR013032 IPR006209. 42.0976
IPR002383 Coagulation factor, Gla region IPR006209 EGF-like domain 39.6754
IPR001314 Peptidase S1A, chymotrypsin IPR006209 EGF-like domain 38.8415
IPR001314 Peptidase S1A, chymotrypsin IPR000742 EGF_2. 38.8083
IPR002383 Coagulation factor, Gla region IPR013032 IPR006209. 38.3622
IPR003966 Peptidase S1A, prothrombin IPR000884 Thrombospondin, type I 37.82
IPR001254 Peptidase S1, chymotrypsin IPR000742 EGF_2. 37.3069
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR006209 EGF-like domain 37.2603
IPR001254 Peptidase S1, chymotrypsin IPR006209 EGF-like domain 37.2501
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR000742 EGF_2. 36.1318
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR013032 IPR006209. 36.1244
IPR001314 Peptidase S1A, chymotrypsin IPR008085 Thrombospondin, subtype 1 35.7584
IPR001254 Peptidase S1, chymotrypsin IPR008085 Thrombospondin, subtype 1 34.8379
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR006209 EGF-like domain 34.703
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR001862 Membrane attack complex component/perforin/complement C9 33.5862
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR008085 Thrombospondin, subtype 1 32.0141
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR013032 IPR006209. 30.9736
IPR000001 Kringle IPR006209 EGF-like domain 27.7846
IPR000001 Kringle IPR000742 EGF_2. 27.4564
IPR001314 Peptidase S1A, chymotrypsin IPR001862 Membrane attack complex component/perforin/complement C9 26.3409
IPR000001 Kringle IPR008085 Thrombospondin, subtype 1 25.8218
IPR001254 Peptidase S1, chymotrypsin IPR001862 Membrane attack complex component/perforin/complement C9 25.7374
IPR001314 Peptidase S1A, chymotrypsin IPR000884 Thrombospondin, type I 25.7203
IPR001254 Peptidase S1, chymotrypsin IPR000884 Thrombospondin, type I 25.0043
IPR000001 Kringle IPR013032 IPR006209. 24.7346
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR000884 Thrombospondin, type I 23.1366
IPR000001 Kringle IPR000884 Thrombospondin, type I 18.9805
IPR003966 Peptidase S1A, prothrombin IPR013032 IPR006209. 16.0978
IPR000001 Kringle IPR002172 Low density lipoprotein-receptor, class A 10.857
IPR003966 Peptidase S1A, prothrombin IPR006209 EGF-like domain 9.68573
IPR003966 Peptidase S1A, prothrombin IPR000742 EGF_2. 9.58987
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR000436 Sushi domain/SCR domain/CCP module 9.04003
IPR012051 Thrombin. IPR013032 IPR006209. 8.35366
IPR012051 Thrombin. IPR000742 EGF_2. 7.53257
IPR001314 Peptidase S1A, chymotrypsin IPR002172 Low density lipoprotein-receptor, class A 6.18291
IPR001254 Peptidase S1, chymotrypsin IPR002172 Low density lipoprotein-receptor, class A 5.90328
IPR001314 Peptidase S1A, chymotrypsin IPR000436 Sushi domain/SCR domain/CCP module 5.89563
IPR001254 Peptidase S1, chymotrypsin IPR000436 Sushi domain/SCR domain/CCP module 5.64176
IPR012051 Thrombin. IPR006209 EGF-like domain 5.13532
IPR000001 Kringle IPR000436 Sushi domain/SCR domain/CCP module 3.06909
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR002172 Low density lipoprotein-receptor, class A 2.89466

The background colour of the table refers to:

  • Blue Domain is only present in F2
  • Yellow Domain is only present in C6
  • Green Domain is present in both F2 and C6

 0.174
Post-translational Modifications

Protein: F2

PTMResidueReference
4-carboxyglutamate 49 HPRD
4-carboxyglutamate 50 HPRD
4-carboxyglutamate 57 HPRD
4-carboxyglutamate 59 HPRD
4-carboxyglutamate 62 HPRD
4-carboxyglutamate 63 HPRD
4-carboxyglutamate 68 HPRD
4-carboxyglutamate 69 HPRD
4-carboxyglutamate 72 HPRD
4-carboxyglutamate 75 HPRD
Carboxylation 49 PubMed, HPRD
Carboxylation 50 PubMed, HPRD
Carboxylation 57 PubMed, HPRD
Carboxylation 59 PubMed, HPRD
Carboxylation 62 PubMed, HPRD
Carboxylation 63 PubMed, HPRD
Carboxylation 68 PubMed, HPRD
Carboxylation 69 PubMed, HPRD
Carboxylation 72 PubMed, HPRD
Carboxylation 75 PubMed, HPRD
Glycosylation 121 PubMed, HPRD
Glycosylation 143 PubMed, HPRD
N-linked 121 PubMed, HPRD
N-linked 143 PubMed, HPRD
N-linked 416 PubMed, HPRD
Proteolytic Cleavage 198 PubMed, HPRD
Proteolytic Cleavage 314 PubMed, HPRD
Proteolytic Cleavage 327 PubMed, HPRD
Proteolytic Cleavage 436 PubMed, HPRD

Protein: C6

PTMResidueReference
C-linked 29 PubMed, HPRD
C-linked 32 PubMed, HPRD
C-linked 90 PubMed, HPRD
C-linked 568 PubMed, HPRD
C-linked 571 PubMed, HPRD
C-linked 574 PubMed, HPRD
Disulfide Bridge 801 PubMed, HPRD
Disulfide Bridge 816 PubMed, HPRD
Disulfide Bridge 823 PubMed, HPRD
Disulfide Bridge 837 PubMed, HPRD
Disulfide Bridge 873 PubMed, HPRD
Disulfide Bridge 897 PubMed, HPRD
Disulfide Bridge 912 PubMed, HPRD
Disulfide Bridge 919 PubMed, HPRD
Disulfide Bridge 932 PubMed, HPRD
Glycosylation 29 PubMed, HPRD
Glycosylation 32 PubMed, HPRD
Glycosylation 90 PubMed, HPRD
Glycosylation 324 PubMed, HPRD
Glycosylation 568 PubMed, HPRD
Glycosylation 571 PubMed, HPRD
Glycosylation 574 PubMed, HPRD
Glycosylation 855 PubMed, HPRD
N-linked 324 PubMed, HPRD
N-linked 855 PubMed, HPRD
Localisation

Protein: F2

LocalisationReference
Secreted HPRD

Protein: C6

LocalisationReference
Secreted HPRD
Transitive Score

The common interactors between F2 and C6 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between F2 andC6. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , F2 has 909 interactors and C6 has 917 interactors of which there are 641 common interactors.

Common InteractorName of Common InteractorScore for F2-Interactor (?)Score for C6-Interactor (?)
F10 F10: Coagulation factor X precursor 2.47E3 1.71
PLG PLG: Plasminogen precursor 826.00 0.804
F9 F9: Coagulation factor IX precursor 386.00 0.486
SERPINB1 SERPINB1, ELANH2, MNEI, PI2: Leukocyte elastase inhibitor 370.00 0.097
SERPINF2 SERPINF2, AAP, PLI: Alpha-2-antiplasmin precursor 50.50 5.75
SERPIND1 SERPIND1, HCF2: Heparin cofactor 2 precursor 50.50 1.81
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 50.50 1.91
SERPING1 SERPING1, C1IN, C1NH: Plasma protease C1 inhibitor precursor 50.50 1.91
ITIH4 ITIH4, IHRP, PRO1851, ITIHL1, PK120: Inter-alpha-trypsin inhibitor heavy chain H 50.50 2.75
SERPINA4 SERPINA4, KST, PI4: Kallistatin precursor 50.50 5.45
SERPINC1 SERPINC1, AT3, PRO0309: Antithrombin-III precursor 45.20 1.71
SERPINA1 SERPINA1, AAT, PRO0684, PI, PRO2209: Alpha-1-antitrypsin precursor 16.80 0.852
AGT AGT, SERPINA8: Angiotensinogen precursor 16.80 0.852
SERPINA6 SERPINA6, CBG: Corticosteroid-binding globulin precursor 16.80 1.81
SERPINA10 SERPINA10, ZPI, UNQ707/PRO1358: Protein Z-dependent protease inhibitor precursor 7.89 0.515
IGFALS IGFALS, ALS: Insulin-like growth factor-binding protein complex acid labile chai 6.17 1.62
HPX HPX: Hemopexin precursor 5.75 5.75
HP HP: Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta c 5.75 1.81
VTN VTN: Vitronectin precursor 5.75 1.91
F12 F12: Coagulation factor XII precursor 5.75 1.81
APCS APCS, PTX2: Serum amyloid P-component precursor 5.75 5.75
AMBP AMBP, HCP, ITIL: AMBP protein precursor [Contains: Alpha-1-microglobulin 5.75 1.81
HGFAC HGFAC: Hepatocyte growth factor activator precursor 5.75 1.81
C8A C8A: Complement component C8 alpha chain precursor 5.75 1.91
PROC PROC: Vitamin K-dependent protein C precursor 5.15 1.71
APOC3 APOC3: Apolipoprotein C-III precursor 5.03 0.307
AHSG AHSG, FETUA, PRO2743: Alpha-2-HS-glycoprotein precursor 5.03 1.67
PON3 PON3: Serum paraoxonase/lactonase 3 5.03 0.307
C8G C8G: Complement component C8 gamma chain precursor 5.03 1.91
HAMP HAMP, HEPC, UNQ487/PRO1003, LEAP1: Hepcidin precursor 5.03 1.67
APOA1 APOA1: Apolipoprotein A-I precursor 5.03 1.81
ORM2 ORM2, AGP2: Alpha-1-acid glycoprotein 2 precursor 5.03 5.75
RNASE4 ANG, RNASE5: Angiogenin precursor 5.03 1.67
HRG HRG: Histidine-rich glycoprotein precursor 5.03 1.67
APOA2 APOA2: Apolipoprotein A-II precursor 5.03 1.81
APOC4 APOC2, APC2: Apolipoprotein C-II precursor 5.03 0.307
ORM1 ORM1, AGP1: Alpha-1-acid glycoprotein 1 precursor 5.03 1.91
PON1 N/A 5.03 0.307
SERPINA3 N/A 4.77 0.852
F5 F5: Coagulation factor V precursor 4.77 0.416
SERPINF1 SERPINF1, PEDF: Pigment epithelium-derived factor precursor 3.85 0.416
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 3.45 0.956
ASGR2 ASGR2: Asialoglycoprotein receptor 2 3.16 1.19
SERPINA7 SERPINA7, TBG: Thyroxine-binding globulin precursor 2.84 0.307
HPN HPN, TMPRSS1: Serine protease hepsin 2.83 0.943
C3 1.91 1.91
APOH APOH, B2G1: Beta-2-glycoprotein 1 precursor 1.91 1.91
C4BPA C4BPA, C4BP: C4b-binding protein alpha chain precursor 1.91 1.81
C2 C2: Complement C2 precursor 1.91 1.81
CFB CFB, BF, BFD: Complement factor B precursor 1.91 1.81
C4BPB C4BPB: C4b-binding protein beta chain precursor 1.91 5.45
CP CP: Ceruloplasmin precursor 1.76 0.191
C8B C8B: Complement component C8 beta chain precursor 1.71 1.71
ALB ALB: Uncharacterized protein ALB 1.67 0.852
ANPEP ANPEP, APN, CD13, PEPN: Aminopeptidase N 1.60 0.192
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 1.53 0.109
SERPINA5 SERPINA5, PCI, PLANH3, PROCI: Plasma serine protease inhibitor precursor 1.41 0.152
SERPINB4 SERPINB3, SCCA, SCCA1: Serpin B3 1.14 0.109
ASGR1 ASGR1: Asialoglycoprotein receptor 1 1.07 0.503
SERPINB13 SERPINB13, PI13: Serpin B13 1.02 0.111
F8 F8, F8C: Coagulation factor VIII precursor 1.00 0.130
SLC14A2 SLC14A2, HUT2, UT2: Urea transporter, kidney 1.00 0.109
SAA4 SAA4, CSAA: Serum amyloid A-4 protein precursor 0.954 0.160
APOC4 APOC4: Apolipoprotein C-IV precursor 0.954 0.053
SERPINI1 SERPINI1, PI12: Neuroserpin precursor 0.902 0.088
SERPINE1 SERPINE1, PAI1, PLANH1: Plasminogen activator inhibitor 1 precursor 0.902 0.109
NEO1 NEO1, NGN: Neogenin precursor 0.902 0.073
HABP2 HABP2, HGFAL, PHBP: Hyaluronan-binding protein 2 precursor 0.881 0.293
HPR HPR: Haptoglobin-related protein precursor 0.881 0.293
AFM AFM, ALB2, ALBA: Afamin precursor 0.785 0.852
KNG1 N/A 0.785 0.475
TTR TTR, PALB: Transthyretin precursor 0.785 0.144
APOM APOM, G3A, HSPC336, NG20: Apolipoprotein M 0.785 0.543
APOE APOE: Apolipoprotein E precursor 0.785 0.852
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.770 0.097
LCAT LCAT: Phosphatidylcholine-sterol acyltransferase precursor 0.708 6.31
MST1 N/A 0.704 0.704
TF TF, PRO1400: Serotransferrin precursor 0.704 0.078
LMAN2 LMAN2, C5orf8: Vesicular integral-membrane protein VIP36 precursor 0.594 0.057
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.575 0.0688
PTGS1 PTGS1, COX1: Prostaglandin G/H synthase 1 precursor 0.575 0.575
CDO1 CDO1: Cysteine dioxygenase type 1 0.558 0.094
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.543 0.438
CFHR2 CFHR2, CFHL2, FHR2, HFL3: Complement factor H-related protein 2 precursor 0.543 0.515
C1R C1R: Complement C1r subcomponent precursor 0.543 0.898
LPA LPA: Apolipoprotein(a) precursor 0.486 0.461
PCOLCE PCOLCE, PCPE1: Procollagen C-endopeptidase enhancer 1 precursor 0.438 0.438
C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 0.393 0.393
FGB FGB: Fibrinogen beta chain precursor [Contains: Fibrinopeptide B] 0.393 0.372
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.393 0.393
ITIH2 N/A 0.384 0.384
TFR2 TFR2, hCG_20451: Uncharacterized protein TFR2 0.366 0.172
AGXT AGXT, AGT1, SPAT: Serine--pyruvate aminotransferase 0.351 0.043
PCSK2 PCSK2, NEC2: Neuroendocrine convertase 2 precursor 0.338 0.041
ENPEP ENPEP: Glutamyl aminopeptidase 0.338 0.041
CFH CFH, HF, HF1, HF2: Complement factor H precursor 0.324 0.307
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.318 0.037
CCL14 CCL14, NCC2, SCYA14: Small-inducible cytokine A14 precursor 0.318 0.307
CFHR4 CFHR4, CFHL4, FHR4: Complement factor H-related protein 4 precursor 0.293 0.137
CETP CETP: Cholesteryl ester transfer protein precursor 0.283 0.052
NTF3 NTF3: Neurotrophin-3 precursor 0.283 0.384
SERPINB10 SERPINB10, PI10: Serpin B10 0.274 0.028
A2M A2M, FWP007: Alpha-2-macroglobulin precursor 0.265 0.251
EDN2 EDN2: Endothelin-2 precursor 0.265 0.0425
C1S C1S: Complement C1s subcomponent precursor 0.265 0.324
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.265 0.251
SHBG SHBG: Sex hormone-binding globulin precursor 0.265 0.251
SERPINA11 SERPINA11: Serpin A11 precursor 0.265 0.027
HEPH HEPH, KIAA0698, UNQ2562/PRO6242: Hephaestin precursor 0.265 0.027
CPXM CPXM1, CPX1, UNQ3015/PRO9782, CPXM: Probable carboxypeptidase X1 precursor 0.265 0.027
SERPINH1 SERPINH1, CBP1, PIG14, CBP2, HSP47, SERPINH2: Serpin H1 precursor 0.265 0.027
CPXM2 CPXM2, UNQ676/PRO1310: Carboxypeptidase-like protein X2 precursor 0.265 0.027
SERPINA12 SERPINA12: Serpin A12 precursor 0.265 0.027
CCL1 CCL1, SCYA1: Small-inducible cytokine A1 precursor 0.241 0.201
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.241 0.077
SLC37A4 G6PC, G6PT: Glucose-6-phosphatase 0.236 0.038
SEPP1 SEPP1, SELP: Selenoprotein P precursor 0.232 0.0425
TFF2 TFF2, SML1: Trefoil factor 2 precursor 0.232 0.070
OPTC OPTC, OPT: Opticin precursor 0.209 0.174
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.209 0.165
LOC643930 CCL3L1, D17S1718, G0S19-2, SCYA3L1: Small-inducible cytokine A3-like 1 precursor 0.209 0.165
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.209 0.083
FN1 N/A 0.209 0.174
THPO THPO, MGDF: Thrombopoietin precursor 0.209 0.152
KITLG KITLG, MGF, SCF: Kit ligand precursor 0.209 0.152
CSF3 CSF3, GCSF: Granulocyte colony-stimulating factor precursor 0.209 0.152
DCN DCN: Decorin precursor 0.209 0.165
CCL26 CCL26, SCYA26, UNQ216/PRO242: Small-inducible cytokine A26 precursor 0.209 0.174
C1QC C1QC, C1QG: Complement C1q subcomponent subunit C precursor 0.209 0.174
CCL15 CCL15, MIP5, NCC3, SCYA15: Small-inducible cytokine A15 precursor 0.209 0.174
IL4 IL4: Interleukin-4 precursor 0.209 0.028
IFNG IFNG: Interferon gamma precursor 0.209 0.028
PZP PZP: Pregnancy zone protein precursor 0.201 0.265
CXCL9 CXCL9, CMK, MIG, SCYB9: Small-inducible cytokine B9 precursor 0.201 0.191
DSPG3 EPYC, DSPG3, PGLB: Epiphycan precursor 0.192 0.152
BGN BGN: Biglycan precursor 0.192 0.152
C1QA C1QA: Complement C1q subcomponent subunit A precursor 0.192 0.161
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.187 0.165
FGA N/A 0.180 0.180
CRP CRP, PTX1: C-reactive protein precursor [Contains: C-reactive protein(1-205)] 0.176 0.283
TFPI TFPI, LACI, TFPI1: Tissue factor pathway inhibitor precursor 0.174 0.165
BGLAP BGLAP: Osteocalcin precursor 0.174 0.174
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.174 0.165
GRN GRN: Granulins precursor 0.174 0.028
F11 F11: Coagulation factor XI precursor 0.174 0.174
CFHR1 CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2: Complement factor H-relate 0.174 0.165
C4A C4A: Complement C4-A precursor 0.174 0.165
CD46 N/A 0.165 0.165
CMA1 CMA1, CYH, CYM: Chymase precursor 0.161 0.152
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.161 0.152
ANGPTL3 ANGPTL3, ANGPT5, UNQ153/PRO179: Angiopoietin-related protein 3 precursor 0.161 0.152
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.161 0.123
CFI CFI, IF: Complement factor I precursor 0.161 0.191
F13B F13B: Coagulation factor XIII B chain precursor 0.161 0.152
SLC10A1 SLC10A1, NTCP, GIG29: Sodium/bile acid cotransporter 0.160 0.053
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.156 0.174
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.156 0.148
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.156 0.156
BMP1 N/A 0.156 0.148
KLK3 KLK3, APS: Prostate-specific antigen precursor 0.156 0.148
F7 F7: Coagulation factor VII precursor 0.156 0.156
SPOCK1 SPOCK1, SPOCK, TIC1, TICN1: Testican-1 precursor 0.156 0.148
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.156 0.148
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.156 0.165
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.156 0.148
COL18A1 N/A 0.156 0.148
CPB2 CPB2: Carboxypeptidase B2 precursor 0.156 0.025
PLAT PLAT: Tissue-type plasminogen activator precursor 0.156 0.156
CCL13 CCL13, MCP4, NCC1, SCYA13: Small-inducible cytokine A13 precursor 0.156 0.123
EPO EPO: Erythropoietin precursor 0.156 0.114
ASPN ASPN: ASPN protein 0.156 0.152
CCL8 CCL8, MCP2, SCYA10, SCYA8: Small-inducible cytokine A8 precursor 0.156 0.123
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.152 0.083
NOG NOG: Noggin precursor 0.152 0.152
PLAU Plasminogen activator, urokinase 0.152 0.028
LECT1 LECT1, CHMI: Chondromodulin-1 precursor 0.152 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.152 0.028
PLTP PLTP: Phospholipid transfer protein precursor 0.152 0.152
ECM1 ECM1: Extracellular matrix protein 1 precursor 0.152 0.165
CSF1 CSF1: Macrophage colony-stimulating factor 1 precursor 0.152 0.152
GHRL GHRL, MTLRP, UNQ524/PRO1066: Appetite-regulating hormone precursor 0.152 0.028
GRP Gastrin-releasing peptide 0.152 0.028
MMRN2 MMRN2, EMILIN3: Multimerin-2 precursor 0.152 0.083
CCL14 N/A 0.152 0.028
NULL A1BG: Alpha-1B-glycoprotein precursor 0.152 0.209
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.152 0.083
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.152 0.209
PTHLH N/A 0.152 0.028
GUCA2A GUCA2A, GUCA2: Guanylin precursor 0.152 0.152
PCSK6 N/A 0.152 0.028
CST4 CST4: Cystatin-S precursor 0.152 0.152
ACCN3 ACCN3, ASIC3, SLNAC1, TNAC1: Amiloride-sensitive cation channel 3 0.152 0.028
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.144 0.144
GNMT GNMT: Glycine N-methyltransferase 0.144 0.0479
IGF2 IGF2, PP1446: Insulin-like growth factor II precursor 0.140 0.152
GAST GAST, GAS: Gastrin precursor [Contains: Gastrin-71 0.140 0.191
AFP AFP, HPAFP: Alpha-fetoprotein precursor 0.140 0.152
AGRP AGRP, AGRT, ART: Agouti-related protein precursor 0.140 0.114
IL22 IL22, ILTIF, UNQ3099/PRO10096: Interleukin-22 precursor 0.140 0.140
WNT2B WNT2B, WNT13: Protein Wnt-2b precursor 0.140 0.191
COL3A1 COL3A1: Collagen alpha-1(III) chain precursor 0.137 0.130
ADIPOQ ADIPOQ, ACDC, ACRP30, APM1, GBP28: Adiponectin precursor 0.137 0.161
CCL11 CCL11, SCYA11: Eotaxin precursor 0.137 0.109
CCL4 CCL4, CCL4L, LAG1, MIP1B, SCYA4, SCYA4L: Small-inducible cytokine A4 precursor 0.137 0.109
IL3 IL3: Interleukin-3 precursor 0.137 0.100
LUM LUM, LDC: Lumican precursor 0.137 0.123
CCL2 CCL2, MCP1, SCYA2: Small-inducible cytokine A2 precursor 0.137 0.109
OSM OSM: Oncostatin-M precursor 0.137 0.090
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.137 0.109
COL5A2 N/A 0.137 0.123
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.137 0.137
CCL5 CCL5, D17S136E, SCYA5: Small-inducible cytokine A5 precursor 0.137 0.109
XCL1 XCL1, LTN, SCYC1: Lymphotactin precursor 0.137 0.115
KERA KERA: Keratocan precursor 0.137 0.109
COL17A1 COL17A1, BP180, BPAG2: Collagen alpha-1(XVII) chain 0.137 0.109
CSH2 GH1: Somatotropin precursor 0.137 0.100
CCL21 CCL21, SCYA21, UNQ784/PRO1600: Small-inducible cytokine A21 precursor 0.137 0.109
COL1A1 COL1A1: Collagen alpha-1(I) chain precursor 0.137 0.130
IL6 IL6, IFNB2: Interleukin-6 precursor 0.137 0.100
CCL24 CCL24, MPIF2, SCYA24: Small-inducible cytokine A24 precursor 0.137 0.123
CNTN4 CNTN4: Contactin-4 precursor 0.137 0.075
ITM2C ITM2C, BRI3, hucep-14, NPD018, PSEC0047: Integral membrane protein 2C 0.137 0.025
VNN1 VNN1: Pantetheinase precursor 0.137 0.025
CA11 CA11, CARP2, UNQ211/PRO237: Carbonic anhydrase-related protein 11 precursor 0.137 0.025
CNTN1 CNTN1: Contactin-1 precursor 0.137 0.075
LOC641705 AMY2A: Pancreatic alpha-amylase precursor 0.137 0.025
THBD THBD, THRM: Thrombomodulin precursor 0.130 0.123
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.130 0.161
CXCL11 CXCL11, ITAC, SCYB11, SCYB9B: Small-inducible cytokine B11 precursor 0.130 0.123
CLEC3B CLEC3B, TNA: Tetranectin precursor 0.130 0.130
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.130 0.123
PRSS22 PRSS22, BSSP4, SP001LA, PRSS26, UNQ302/PRO343: Brain-specific serine protease 4 0.130 0.191
CXCL12 Stromal cell-derived factor 1 delta 0.130 0.123
CXCL10 CXCL10, INP10, SCYB10: Small-inducible cytokine B10 precursor 0.130 0.152
TST TST: Thiosulfate sulfurtransferase 0.126 0.042
PF4V1 PF4V1, SCYB4V1: Platelet factor 4 variant precursor 0.123 0.123
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.123 0.097
VWF VWF, F8VWF: von Willebrand factor precursor 0.123 0.103
MMP8 CLG1, MMP8: Neutrophil collagenase precursor 0.117 0.123
MMP11 MMP11, STMY3: Stromelysin-3 precursor 0.117 0.109
TIMP1 TIMP1, CLGI, TIMP: Metalloproteinase inhibitor 1 precursor 0.117 0.136
PRG4 PRG4, MSF, SZP: Proteoglycan-4 precursor 0.117 0.136
LGALS3 LGALS3, MAC2: Galectin-3 0.115 0.109
COL5A1 N/A 0.115 0.130
SFTPA2 SFTPA2, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A2 precursor 0.115 0.115
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.115 0.055
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.115 0.062
REG1B REG1A, PSPS, REG: Lithostathine 1 alpha precursor 0.115 0.201
MMP13 MMP13: Collagenase 3 precursor 0.115 0.109
CTSG CTSG: Cathepsin G precursor 0.115 0.123
IL8 IL8: Interleukin-8 precursor 0.115 0.109
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.115 0.109
COL15A1 COL15A1: Collagen alpha-1(XV) chain precursor [Contains: Endostatin 0.115 0.115
UMOD UMOD: Uromodulin precursor 0.115 0.109
REG3A REG3A, HIP, PAP, PAP1: Regenerating islet-derived protein 3 alpha precursor 0.115 0.191
IL2RA IL2RA: Interleukin-2 receptor alpha chain precursor 0.115 0.130
PPBP PPBP, CTAP3, SCYB7, TGB1, THBGB1: Platelet basic protein precursor 0.115 0.115
PRTN3 PRTN3, MBN: Myeloblastin precursor 0.115 0.109
PRSS1 PRSS1, TRP1, TRY1, TRYP1: Trypsin-1 precursor 0.115 0.152
PF4 PF4, CXCL4, SCYB4: Platelet factor 4 precursor 0.115 0.115
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.115 0.109
ELA3B ELA3B: Elastase-3B precursor 0.115 0.191
PRG2 PRG2, MBP: Bone marrow proteoglycan precursor 0.115 0.109
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.115 0.115
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.115 0.123
GZMB Endogenous granzyme B 0.115 0.109
CXCL5 CXCL5, ENA78, SCYB5: Small-inducible cytokine B5 precursor 0.115 0.109
SPINT2 SPINT2, HAI2, KOP: Kunitz-type protease inhibitor 2 precursor 0.115 0.098
TG TG: Thyroglobulin precursor 0.115 0.109
TACSTD1 TACSTD1, GA733-2, M1S2, M4S1, MIC18, TROP1: Tumor-associated calcium signal tran 0.115 0.130
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.115 0.109
CFP CFP, PFC: Properdin precursor 0.115 0.115
MMP9 MMP9, CLG4B: Matrix metalloproteinase-9 precursor 0.115 0.123
AZU1 AZU1: Azurocidin precursor 0.115 0.109
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.115 0.123
CCL22 CCL22, A-152E5.1, MDC, SCYA22: Small-inducible cytokine A22 precursor 0.115 0.109
NOTCH4 N/A 0.115 0.109
ELA2 ELA2: Leukocyte elastase precursor 0.115 0.109
REG1B REG1B, REGL: Lithostathine 1 beta precursor 0.115 0.191
CXCL1 CXCL1, GRO, GRO1, GROA, MGSA, SCYB1: Growth-regulated protein alpha precursor 0.115 0.109
SPINK1 SPINK1, PSTI: Pancreatic secretory trypsin inhibitor precursor 0.115 0.096
CSPG2 N/A 0.115 0.098
MUC2 MUC2, SMUC: Mucin-2 precursor 0.115 0.109
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.114 0.062
FSHB FSHB: Follitropin subunit beta precursor 0.114 0.130
HLA-DQB2 HLA-DQB2, DASS-256O6.1-002, XXbac-BCX231H22.1-002, XXbac-BPG3L13.3-002: Major hi 0.114 0.026
TFF1 TFF1, BCEI, PS2: Trefoil factor 1 precursor 0.114 0.140
CST5 CST5: Cystatin-D precursor 0.114 0.114
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.114 0.077
SFTPB SFTPB, SFTP3: Pulmonary surfactant-associated protein B precursor 0.114 0.114
AOC3 AOC3, VAP1: Membrane copper amine oxidase 0.114 0.026
IFNA14 IFNA14: Interferon alpha-14 precursor 0.114 0.026
GUCA2B GUCA2B: Guanylate cyclase activator 2B precursor [Contains: Guanylate cyclase C- 0.114 0.114
RLN2 RLN2: Prorelaxin H2 precursor [Contains: Relaxin B chain; Relaxin A chain] 0.114 0.130
LIPG LIPG, UNQ387/PRO719: Endothelial lipase precursor 0.114 0.123
IL1RN IL1RN, IL1F3, IL1RA: Interleukin-1 receptor antagonist protein precursor 0.114 0.026
TSHB TSHB: Thyrotropin subunit beta precursor 0.114 0.130
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.111 0.097
LGALS1 LGALS1: Galectin-1 0.109 0.109
IL15RA IL15RA: Interleukin-15 receptor alpha chain precursor 0.109 0.109
MGP MGP, MGLAP, GIG36: Matrix Gla protein precursor 0.109 0.123
FGL2 FGL2: Fibroleukin precursor 0.103 0.088
TNC TNC, HXB: Tenascin precursor 0.103 0.111
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.103 0.111
MMP2 MMP2, CLG4A: 72 kDa type IV collagenase precursor 0.103 0.123
MFAP4 MFAP4: Microfibril-associated glycoprotein 4 precursor 0.103 0.111
COL4A1 N/A 0.103 0.117
CPM CPM: Carboxypeptidase M precursor 0.103 0.102
CPB1 CPB1, CPB, PCPB: Carboxypeptidase B precursor 0.103 0.086
SPARC SPARC, ON: SPARC precursor 0.103 0.103
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.103 0.111
LAMA2 LAMA2: Uncharacterized protein LAMA2 0.103 0.136
KLK6 KLK6, PRSS18, PRSS9: Kallikrein-6 precursor 0.103 0.093
THBS1 THBS1, TSP, TSP1: Thrombospondin-1 precursor 0.103 0.130
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.103 0.111
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.103 0.111
MMP1 MMP1, CLG: Interstitial collagenase precursor 0.103 0.109
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.103 0.111
SFTPD SFTPD, PSPD, SFTP4: Pulmonary surfactant-associated protein D precursor 0.103 0.109
CPA2 CPA2: Carboxypeptidase A2 precursor 0.103 0.086
MMP7 MMP7, MPSL1, PUMP1: Matrilysin precursor 0.103 0.123
KLK1 KLK1: Kallikrein-1 precursor 0.103 0.136
CTGF CTGF, CCN2, HCS24: Connective tissue growth factor precursor 0.103 0.097
C7 C7: Complement component C7 precursor 0.103 0.117
SPON1 SPON1, KIAA0762, VSGP: Spondin-1 precursor 0.103 0.117
PLA2G7 PAFAH, PLA2G7: Platelet-activating factor acetylhydrolase precursor 0.102 0.123
LIPF LIPF: Gastric triacylglycerol lipase precursor 0.102 0.117
PTGDS PTGDS, PDS: Prostaglandin-H2 D-isomerase precursor 0.100 0.098
LCN2 LCN2, HNL, NGAL: Neutrophil gelatinase-associated lipocalin precursor 0.100 0.123
NDP NDP: Norrin precursor 0.100 0.115
NPPC NPPC, CNP2: C-type natriuretic peptide precursor [Contains: CNP-22; CNP-29; CNP- 0.100 0.114
CCK CCK: Cholecystokinins precursor 0.100 0.109
PAEP PAEP: Glycodelin precursor 0.100 0.109
LHB LHB: Lutropin subunit beta precursor 0.100 0.109
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.100 0.055
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.100 0.055
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.100 0.049
THBS2 N/A 0.100 0.100
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.100 0.055
RNASE2 RNASE2, EDN, RNS2: Non-secretory ribonuclease precursor 0.100 0.100
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.100 0.055
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.100 0.115
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.100 0.124
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.100 0.055
CEL CEL, RP11-326L24.2-001: Carboxyl ester lipase 0.100 0.201
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.100 0.062
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.100 0.055
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.100 0.055
IAPP IAPP: Islet amyloid polypeptide precursor 0.100 0.100
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.100 0.109
PAPPA PAPPA, RP11-45A16.1-001: Pregnancy-associated plasma protein A, pappalysin 1 (Fr 0.100 0.100
RNASE1 RNASE1, RIB1, RNS1: Ribonuclease pancreatic precursor 0.100 0.100
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.100 0.055
MFAP2 MFAP2, MAGP1: Microfibrillar-associated protein 2 precursor 0.100 0.115
NPPA NPPA, ANP, PND: Atrial natriuretic factor precursor 0.100 0.100
INHA INHA: Inhibin alpha chain precursor 0.100 0.123
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.100 0.062
CGA CGA: Glycoprotein hormones alpha chain precursor 0.100 0.109
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.100 0.137
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.100 0.137
HLA-DRA 0.100 0.090
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.100 0.115
INS INS: Insulin precursor [Contains: Insulin B chain; Insulin A chain] 0.100 0.152
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.099 0.090
COL16A1 COL16A1: Collagen alpha-1(XVI) chain precursor 0.098 0.109
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.098 0.098
ALK ALK: ALK tyrosine kinase receptor precursor 0.097 0.097
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.097 0.097
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.096 0.096
DLK1 DLK1, DLK: Delta-like protein precursor 0.096 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.096 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.096 0.109
TMPRSS9 N/A 0.096 0.109
THOP1 THOP1: Thimet oligopeptidase 0.094 0.0794
SLIT2 SLIT2, SLIL3: Slit homolog 2 protein precursor 0.093 0.088
TRHR TRHR: Thyrotropin-releasing hormone receptor 0.090 0.034
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.090 0.073
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.0898 0.044
FGF9 FGF9: Glia-activating factor precursor 0.0898 0.055
APOD APOD: Apolipoprotein D precursor 0.0898 0.103
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.0898 0.097
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.0898 0.088
PNLIP PNLIP: Pancreatic triacylglycerol lipase precursor 0.0898 0.136
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.0898 0.103
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.0898 0.088
FIGF FIGF, VEGFD: Vascular endothelial growth factor D precursor 0.0898 0.136
WNT3 WNT3, INT4: Proto-oncogene protein Wnt-3 precursor 0.0898 0.109
LTF GIG12: Growth-inhibiting protein 12 0.0898 0.0898
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.088 0.081
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.087 0.109
EDA N/A 0.087 0.109
DRD2 DRD2: D(2) dopamine receptor 0.087 0.0333
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.087 0.0333
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.086 0.098
ATRN N/A 0.086 0.098
JAG2 JAG2: Jagged-2 precursor 0.086 0.098
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.086 0.098
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.086 0.098
MT1M MT1M, MT1K: Metallothionein-1M 0.083 0.083
SPP2 SPP2, SPP24: Secreted phosphoprotein 24 precursor 0.082 0.027
CYP4A22 CYP4A22, RP1-18D14.1-001: Cytochrome P450 4A22. 0.082 0.027
GAMT GAMT, hCG_21569: cDNA FLJ76206, highly similar to Homo sapiens guanidinoacetate 0.082 0.027
SELE SELE, ELAM1: E-selectin precursor 0.081 0.081
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.081 0.081
RHO RHO, OPN2: Rhodopsin 0.080 0.031
GP1BA N/A 0.080 0.100
MEP1B MEP1B: Meprin A subunit beta precursor 0.079 0.090
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.078 0.086
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.078 0.098
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.073 0.073
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.073 0.090
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.073 0.064
CLU 0.0727 0.0727
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.072 0.072
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.072 0.072
SORL1 SORL1: Sortilin-related receptor precursor 0.071 0.072
KEL KEL: Kell blood group glycoprotein 0.071 0.081
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.071 0.071
MARCO MARCO, SCARA2: Macrophage receptor MARCO 0.071 0.429
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.071 0.081
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.071 0.081
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.0688 0.034
PLGLB1 PLGLB1, PLGL, PLGLB2, PLGP1, PRGB: Plasminogen-related protein B precursor 0.067 0.050
LPAL2 LPAL2, apoargC: Apolipoprotein 0.067 0.067
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.065 0.081
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.065 0.081
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.065 0.0453
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.064 0.064
ITGB7 ITGB7: Integrin beta-7 precursor 0.064 0.058
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.064 0.064
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.064 0.058
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.064 0.058
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.064 0.073
IGF2R IGF2R, MPRI: Cation-independent mannose-6-phosphate receptor precursor 0.064 0.046
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.064 0.073
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.064 0.090
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.064 0.090
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.063 0.037
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, testis-specific isoform precursor 0.063 0.072
MME MME, EPN: Neprilysin 0.063 0.100
EGF EGF: Pro-epidermal growth factor precursor 0.063 0.081
ITGB4 N/A 0.063 0.072
F3 F3: Tissue factor precursor 0.063 0.057
SFRP1 CDNA FLJ45402 fis, clone BRHIP3029409, moderately similar to Homo sapiens secret 0.063 0.081
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.063 0.072
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.063 0.065
CD69 CD69: Early activation antigen CD69 0.063 0.057
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.063 0.081
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.063 0.065
AREG AREG, SDGF: Amphiregulin precursor 0.063 0.072
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.062 0.062
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.060 0.113
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.060 0.148
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.058 0.033
GP5 GP5: Platelet glycoprotein V precursor 0.058 0.041
DCC DCC: Netrin receptor DCC precursor 0.058 0.073
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.057 0.065
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.057 0.029
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.057 0.072
GP1BB GP1BB: Platelet glycoprotein Ib beta chain precursor 0.057 0.065
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.057 0.037
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.057 0.072
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.057 0.029
MEP1A MEP1A: Meprin A subunit alpha precursor 0.056 0.073
CSPG4 CSPG4, MCSP: Chondroitin sulfate proteoglycan 4 precursor 0.056 0.064
LDLR LDLR: Low-density lipoprotein receptor precursor 0.056 0.064
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.056 0.058
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.056 0.058
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.056 0.073
SPINK2 SPINK2: Serine protease inhibitor Kazal-type 2 precursor 0.056 0.083
CRLF3 N/A 0.055 0.049
PPP1R1A PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A 0.053 0.025
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.053 0.053
ITGAE ITGAE: Integrin alpha-E precursor 0.052 0.065
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.052 0.052
COL11A1 COL11A1, COLL6: Collagen alpha-1(XI) chain precursor 0.051 0.027
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.051 0.051
ITGA3 ITGA3, MSK18: Integrin alpha-3 precursor 0.051 0.056
TLR4 TLR4: Toll-like receptor 4 precursor 0.051 0.029
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.051 0.029
TSHR N/A 0.051 0.029
ITGA2B ITGA2B, GP2B, ITGAB: Integrin alpha-IIb precursor 0.051 0.064
PTPRZ1 N/A 0.051 0.026
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.051 0.033
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.051 0.113
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.051 0.072
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.050 0.148
RBP4 RBP4, PRO2222: Plasma retinol-binding protein precursor 0.049 0.293
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.049 0.044
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.049 0.049
ITGAV ITGAV, MSK8, VNRA: Integrin alpha-V precursor 0.0462 0.064
LMAN1 LMAN1, ERGIC53, F5F8D: Protein ERGIC-53 precursor 0.046 0.041
XRCC1 XRCC1: DNA-repair protein XRCC1 0.045 0.041
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.044 0.109
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.042 0.042
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.041 0.090
MASP1 MASP1, CRARF, CRARF1, PRSS5: Complement-activating component of Ra-reactive fact 0.041 0.041
TPSG1 TPSG1, PRSS31, TMT: Tryptase gamma precursor 0.041 0.041
IGFBP2 IGFBP2, BP2, IBP2: Insulin-like growth factor-binding protein 2 precursor 0.041 0.041
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.041 0.037
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.041 0.037
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.040 0.137
SELP SELP, GMRP, GRMP: P-selectin precursor 0.039 0.039
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.038 0.075
ARMET ARMET, ARP: Protein ARMET precursor 0.038 0.029
CYP2B6 CYP2B6: Cytochrome P450 2B6 0.038 0.042
FNTB FNTB: Protein farnesyltransferase subunit beta 0.037 0.111
IL9R IL9R: Interleukin-9 receptor precursor 0.037 0.037
CD55 CD55, CR, DAF: Complement decay-accelerating factor precursor 0.037 0.098
CANX CANX: Calnexin precursor 0.037 0.037
ANGPTL4 ANGPTL4, ARP4, PP1158, HFARP, PSEC0166, PGAR, UNQ171/PRO197: Angiopoietin-relate 0.036 0.041
FGL1 FGL1, HFREP1: Fibrinogen-like protein 1 precursor 0.036 0.044
LGALS4 LGALS4: Galectin-4 0.036 0.044
PKD1 PKD1: Polycystin-1 precursor 0.0338 0.0338
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.0333 0.087
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.0333 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.0333 0.087
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.0333 0.049
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.0333 0.109
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.0333 0.109
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.0333 0.109
CSF3R N/A 0.0333 0.0333
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.0333 0.049
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.0333 0.049
TPBG TPBG, 5T4: Trophoblast glycoprotein precursor 0.032 0.072
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.032 0.029
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.032 0.037
GP9 GP9: Platelet glycoprotein IX precursor 0.032 0.072
SLITRK5 SLITRK5, KIAA0918, LRRC11: SLIT and NTRK-like protein 5 precursor 0.032 0.065
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.032 0.032
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.0308 0.044
CFHR5 N/A 0.0308 0.0308
PRSS8 PRSS8: Prostasin precursor 0.0308 0.0308
PVR PVR, PVS: Poliovirus receptor precursor 0.031 0.057
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.031 0.126
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.031 0.0453
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.031 0.037
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.030 0.030
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.030 0.030
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.030 0.030
CRYAA CRYAA, CRYA1, HSPB4: Alpha-crystallin A chain 0.030 0.039
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.030 0.044
BSG N/A 0.030 0.044
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.030 0.044
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.030 0.073
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.029 0.058
FAP FAP: Seprase 0.029 0.051
VEGF vascular endothelial growth factor A isoform a precursor 0.029 0.051
COX6B2 COX6B2: Cytochrome c oxidase subunit VIb isoform 2 0.029 0.029
OLFM1 OLFM1, NOE1, NOEL1: Noelin precursor 0.029 0.051
INSRR INSRR, IRR: Insulin receptor-related protein precursor 0.029 0.029
C1QTNF4 C1QTNF4, CTRP4: Complement C1q tumor necrosis factor-related protein 4 precursor 0.028 0.083
DSP DSP: Desmoplakin 0.028 0.028
IRF2BP2 IRF2BP2, RP4-781K5.1-002: Interferon regulatory factor 2-binding protein 2. 0.028 0.028
TUBGCP6 TUBGCP6, GCP6, KIAA1669: Gamma-tubulin complex component 6 0.028 0.028
PCGF6 N/A 0.028 0.028
LNX1 N/A 0.028 0.028
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.028 0.028
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.028 0.083
CGN N/A 0.028 0.028
APOB APOB: Apolipoprotein B-100 precursor 0.028 0.028
KLK5 KLK5, SCTE, UNQ570/PRO1132: Kallikrein-5 precursor 0.028 0.036
LAMB2 LAMB2, LAMS: Laminin subunit beta-2 precursor 0.028 0.028
MMP24 MMP24, MT5MMP: Matrix metalloproteinase-24 precursor 0.028 0.028
LRP3 LRP3: Low-density lipoprotein receptor-related protein 3 precursor 0.028 0.0308
ANGPT4 ANGPT4, ANG3, ANG4: Angiopoietin-4 precursor 0.028 0.028
C4B C4B, XXbac-BCX116I9.7-001, XXbac-BPG116M5.7-001: C4B1 0.027 0.027
CD207 CD207, CLEC4K: C-type lectin domain family 4 member K 0.027 0.027
C4B C4B: Complement C4-B precursor 0.027 0.051
CSPG5 N/A 0.027 0.051
LTBP1 LTBP1: Latent-transforming growth factor beta-binding protein, isoform 1S precur 0.027 0.051
SPOCK3 SPOCK3, TICN3, UNQ409/PRO771: Testican-3 precursor 0.027 0.051
SPARCL1 SPARCL1: SPARC-like protein 1 precursor 0.027 0.051
ELTD1 ELTD1, RP11-143H12.1-002: EGF, latrophilin and seven transmembrane domain contai 0.027 0.051
FN1 FN1, FN: Fibronectin precursor 0.027 0.051
MST1 MST1, D3F15S2, DNF15S2, HGFL: Hepatocyte growth factor-like protein precursor 0.027 0.051
C5 C5: Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 a 0.027 0.051
ITGB1 ITGB1, FNRB, MDF2, MSK12: Integrin beta-1 precursor 0.027 0.051
PLAU PLAU: Urokinase-type plasminogen activator precursor 0.027 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.027 0.027
KLKB1 N/A 0.027 0.051
CD74 CD74, DHLAG: HLA class II histocompatibility antigen gamma chain 0.027 0.051
MMRN1 MMRN1, ECM, EMILIN4, MMRN: Multimerin-1 precursor 0.027 0.051
COL4A2 COL4A2: Collagen alpha-2(IV) chain precursor [Contains: Canstatin] 0.027 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.027 0.051
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.027 0.033
ADAMTS18 ADAMTS18, ADAMTS21: ADAMTS-18 precursor 0.027 0.027
CLEC3A CLEC3A: C-type lectin domain family 3, member A 0.027 0.027
MASP2 MASP2: Mannan-binding lectin serine protease 2 precursor 0.027 0.027
CSPG3 CSPG3, NCAN, NEUR: Neurocan core protein precursor 0.027 0.027
PRRG4 PRRG4, TMG4: Transmembrane gamma-carboxyglutamic acid protein 4 precursor 0.027 0.027
KLK9 KLK9: Kallikrein-9 precursor 0.027 0.027
CFHR3 CFHR3, CFHL3, FHR3: Complement factor H-related protein 3 precursor 0.027 0.027
PRSS21 PRSS21, ESP1, UNQ266/PRO303, TEST1: Testisin precursor 0.027 0.027
CLEC14A CLEC14A, C14orf27, UNQ236/PRO269, EGFR5: C-type lectin domain family 14 member A 0.027 0.027
KREMEN2 KREMEN2, KRM2: Kremen protein 2 precursor 0.027 0.027
C21orf29 TSPEAR, C21orf29: Protein TSPEAR precursor 0.027 0.027
NTNG2 N/A 0.027 0.027
PAPPA2 PAPPA2, PLAC3: Pappalysin-2 precursor 0.027 0.027
KLK12 KLK12, KLKL5, UNQ669/PRO1303: Kallikrein-12 precursor 0.027 0.027
ND4L MT-ND4L, MTND4L, NADH4L, ND4L: NADH-ubiquinone oxidoreductase chain 4L 0.027 0.027
REG3G REG3G, PAP1B, UNQ429/PRO162: Regenerating islet-derived protein 3 gamma precurso 0.027 0.027
ITLN1 ITLN1, INTL, UNQ640/PRO1270, ITLN, LFR: Intelectin-1 precursor 0.027 0.027
PRRG1 PRRG1, PRGP1, TMG1: Transmembrane gamma-carboxyglutamic acid protein 1 precursor 0.027 0.027
PRSS27 PRSS27, MPN, UNQ1884/PRO4327: Serine protease 27 precursor 0.027 0.027
MUC13 MUC13, DRCC1, UNQ6194/PRO20221, RECC: Mucin-13 precursor 0.027 0.027
WISP3 WISP3, CCN6, UNQ462/PRO790/PRO956: WNT1-inducible-signaling pathway protein 3 pr 0.027 0.027
GP2 GP2: Pancreatic secretory granule membrane major glycoprotein GP2 precursor 0.027 0.027
PLGLA1 PLGLA1, PLGP2: Plasminogen-related protein A precursor 0.027 0.027
LAMC2 LAMC2, LAMB2T, LAMNB2: Laminin subunit gamma-2 precursor 0.027 0.027
WISP3 LIBC, WISP3, RP1-142L7.3-004, hCG_34804: Lost in inflammatory breast cancer tumo 0.027 0.027
ITLN2 ITLN2, UNQ2789/PRO7179: Intelectin-2 precursor 0.027 0.027
SCARF2 SCARF2, SREC2, SREPCR: Scavenger receptor class F member 2 precursor 0.027 0.027
PRRG2 PRRG2, PRGP2, TMG2: Transmembrane gamma-carboxyglutamic acid protein 2 precursor 0.027 0.027
IFRD2 0.027 0.027
CFC1 CFC1: Cryptic protein precursor 0.027 0.027
THSD3 N/A 0.027 0.027
UNQ739 VWC2, UNQ739, hCG_2045125, tcag7.1302: von Willebrand factor C domain-containing 0.027 0.027
NETO1 N/A 0.027 0.027
ADAMTS10 ADAMTS10: ADAMTS-10 precursor 0.027 0.027
REG4 REG4, GISP, RELP: Regenerating islet-derived protein 4 precursor 0.027 0.027
NTN4 NTN4: Netrin-4 precursor 0.027 0.027
TPSAB1 N/A 0.027 0.027
CILP2 CILP2: Cartilage intermediate layer protein 2 precursor 0.027 0.027
ADAMTS17 ADAMTS17: ADAMTS-17 precursor 0.027 0.027
NELL2 NELL2, NRP2: Protein kinase C-binding protein NELL2 precursor 0.027 0.027
ELA2A ELA2A: Elastase-2A precursor 0.027 0.027
COL11A2 COL11A2: Collagen alpha-2(XI) chain precursor 0.027 0.027
PRSS36 PRSS36: Polyserase-2 precursor 0.027 0.027
ADAMTSL1 N/A 0.027 0.027
ADAMTS19 ADAMTS19: ADAMTS-19 precursor 0.027 0.027
CR1L complement component (3b/4b) receptor 1-like 0.027 0.027
HHIP HHIP, HIP, UNQ5825/PRO19644: Hedgehog-interacting protein precursor 0.027 0.027
COX2 MT-CO2, COII, COXII, MTCO2: Cytochrome c oxidase subunit 2 0.027 0.027
DAG1 DAG1: Dystroglycan precursor 0.027 0.038
CES1 CES1, CES2, SES1: Liver carboxylesterase 1 precursor 0.026 0.046
KNG1 KNG1, BDK, KNG: Kininogen-1 precursor 0.026 0.026
MT1F MT1F, PRO0376: Metallothionein-1F 0.025 0.287
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.025
UNC5D N/A 0.025 0.025
SCRIB N/A 0.025 0.028
0.228
Total Score 469.00