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Evidence of Interaction Between PLAT and SERPINI1

The interaction score between PLAT and SERPINI1 is 1.01.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismPLAT OrthologueSERPINI1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
fly Q9V517 0.057 Q9V990 0.074
fly Q9V517 0.057 Q9I7G5 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in PLAT and SERPINI1:
Domains in PLATDomains in SERPINI1
IPR006209 EGF-like domain
IPR000001 Kringle
IPR001254 Peptidase S1, chymotrypsin
IPR001314 Peptidase S1A, chymotrypsin
IPR000083 Fibronectin, type I
IPR000742 EGF_2.
IPR011357 Pept_S1A_tPA.
IPR000215 Proteinase inhibititor I4, serpin

The Chi square scores for co-occurrence of domains that are present in PLAT and SERPINI1 are listed below.

Domain 1Domain 2Chi Square
IPR001314 Peptidase S1A, chymotrypsin IPR000215 Proteinase inhibititor I4, serpin 1406.06
IPR001254 Peptidase S1, chymotrypsin IPR000215 Proteinase inhibititor I4, serpin 1376.58
IPR000001 Kringle IPR000215 Proteinase inhibititor I4, serpin 235.847
IPR011357 Pept_S1A_tPA. IPR000215 Proteinase inhibititor I4, serpin 68.6377
IPR000083 Fibronectin, type I IPR000215 Proteinase inhibititor I4, serpin 42.4798
IPR000742 EGF_2. IPR000215 Proteinase inhibititor I4, serpin 31.7849
IPR006209 EGF-like domain IPR000215 Proteinase inhibititor I4, serpin 21.2701

The background colour of the table refers to:

  • Blue Domain is only present in PLAT
  • Yellow Domain is only present in SERPINI1
  • Green Domain is present in both PLAT and SERPINI1

 1.30
Post-translational Modifications

Protein: PLAT

PTMResidueReference
Disulfide Bridge 278 PubMed, HPRD
Disulfide Bridge 291 PubMed, HPRD
Disulfide Bridge 296 PubMed, HPRD
Glycosylation 96 PubMed, HPRD
Glycosylation 152 PubMed, HPRD
Glycosylation 219 PubMed, HPRD
Glycosylation 483 PubMed, HPRD
N-linked 152 PubMed, HPRD
N-linked 219 PubMed, HPRD
N-linked 483 PubMed, HPRD
O-linked 96 PubMed, HPRD
Proteolytic Cleavage 310 PubMed, HPRD

Protein: SERPINI1

PTMResidueReference
Proteolytic Cleavage 362 PubMed, HPRD
Localisation

Protein: PLAT

LocalisationReference
ER HPRD
Secreted HPRD
Cytoplasm HPRD

Protein: SERPINI1

LocalisationReference
Secreted HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PLAT and SERPINI1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PLAT andSERPINI1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PLAT has 1105 interactors and SERPINI1 has 454 interactors of which there are 340 common interactors.

Common InteractorName of Common InteractorScore for PLAT-Interactor (?)Score for SERPINI1-Interactor (?)
AGT AGT, SERPINA8: Angiotensinogen precursor 1.30 0.026
C1QC C1QC, C1QG: Complement C1q subcomponent subunit C precursor 0.174 0.083
COL1A1 COL1A1: Collagen alpha-1(I) chain precursor 0.174 0.049
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.174 0.055
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.174 0.103
COL3A1 COL3A1: Collagen alpha-1(III) chain precursor 0.174 0.049
BGLAP BGLAP: Osteocalcin precursor 0.174 0.174
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.174 0.156
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.174 0.908
THBS1 THBS1, TSP, TSP1: Thrombospondin-1 precursor 0.174 0.088
ADIPOQ ADIPOQ, ACDC, ACRP30, APM1, GBP28: Adiponectin precursor 0.174 0.055
FN1 N/A 0.174 0.028
COL5A1 N/A 0.174 0.124
C1QA C1QA: Complement C1q subcomponent subunit A precursor 0.174 0.049
C8A C8A: Complement component C8 alpha chain precursor 0.174 0.109
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.165 0.031
NOTCH4 N/A 0.165 0.111
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.165 0.075
HPX HPX: Hemopexin precursor 0.165 0.055
CFHR1 CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2: Complement factor H-relate 0.165 0.165
CFI CFI, IF: Complement factor I precursor 0.165 0.775
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.165 0.035
REG1B REG1A, PSPS, REG: Lithostathine 1 alpha precursor 0.165 0.055
THBD THBD, THRM: Thrombomodulin precursor 0.165 0.110
CTSG CTSG: Cathepsin G precursor 0.165 0.775
MMP7 MMP7, MPSL1, PUMP1: Matrilysin precursor 0.165 0.097
C1R C1R: Complement C1r subcomponent precursor 0.165 0.872
TFPI TFPI, LACI, TFPI1: Tissue factor pathway inhibitor precursor 0.165 0.028
CD46 N/A 0.165 0.165
C4BPA C4BPA, C4BP: C4b-binding protein alpha chain precursor 0.165 0.109
F13B F13B: Coagulation factor XIII B chain precursor 0.165 0.109
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.165 0.031
CLEC3B CLEC3B, TNA: Tetranectin precursor 0.165 0.049
CCK CCK: Cholecystokinins precursor 0.165 0.144
IL15RA IL15RA: Interleukin-15 receptor alpha chain precursor 0.165 0.110
UMOD UMOD: Uromodulin precursor 0.165 0.109
PRG2 PRG2, MBP: Bone marrow proteoglycan precursor 0.165 0.055
APOH APOH, B2G1: Beta-2-glycoprotein 1 precursor 0.165 0.109
COL15A1 COL15A1: Collagen alpha-1(XV) chain precursor [Contains: Endostatin 0.165 0.056
VTN VTN: Vitronectin precursor 0.165 0.055
REG3A REG3A, HIP, PAP, PAP1: Regenerating islet-derived protein 3 alpha precursor 0.165 0.055
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.165 0.035
C2 C2: Complement C2 precursor 0.165 0.859
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.165 0.097
MGP MGP, MGLAP, GIG36: Matrix Gla protein precursor 0.165 0.110
PCOLCE PCOLCE, PCPE1: Procollagen C-endopeptidase enhancer 1 precursor 0.165 0.110
COL5A2 N/A 0.165 0.049
SFTPA2 SFTPA2, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A2 precursor 0.165 0.055
PRSS22 PRSS22, BSSP4, SP001LA, PRSS26, UNQ302/PRO343: Brain-specific serine protease 4 0.165 0.859
GRN GRN: Granulins precursor 0.165 0.025
PRSS1 PRSS1, TRP1, TRY1, TRYP1: Trypsin-1 precursor 0.165 0.859
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.083
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.165 0.034
CFHR2 CFHR2, CFHL2, FHR2, HFL3: Complement factor H-related protein 2 precursor 0.165 0.098
C1S C1S: Complement C1s subcomponent precursor 0.165 0.872
CPE CPE: Carboxypeptidase E precursor 0.165 0.078
AZU1 AZU1: Azurocidin precursor 0.165 0.859
C4BPB C4BPB: C4b-binding protein beta chain precursor 0.165 0.098
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.165 0.052
MUC2 MUC2, SMUC: Mucin-2 precursor 0.165 0.123
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.165 0.859
MMP8 CLG1, MMP8: Neutrophil collagenase precursor 0.165 0.097
CMA1 CMA1, CYH, CYM: Chymase precursor 0.165 0.775
COL17A1 COL17A1, BP180, BPAG2: Collagen alpha-1(XVII) chain 0.165 0.049
ELA3B ELA3B: Elastase-3B precursor 0.165 0.859
GZMB Endogenous granzyme B 0.165 0.859
MMP13 MMP13: Collagenase 3 precursor 0.165 0.109
REG1B REG1B, REGL: Lithostathine 1 beta precursor 0.165 0.055
CSPG2 N/A 0.165 0.098
EDN3 EDN3: Endothelin-3 precursor 0.165 0.026
MMP9 MMP9, CLG4B: Matrix metalloproteinase-9 precursor 0.165 0.098
IL2RA IL2RA: Interleukin-2 receptor alpha chain precursor 0.165 0.123
F11 F11: Coagulation factor XI precursor 0.165 1.30
PRTN3 PRTN3, MBN: Myeloblastin precursor 0.165 0.859
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.165 0.049
ELA2 ELA2: Leukocyte elastase precursor 0.165 0.859
F8 F8, F8C: Coagulation factor VIII precursor 0.165 0.0425
F12 F12: Coagulation factor XII precursor 0.165 0.859
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.165 0.110
MMP11 MMP11, STMY3: Stromelysin-3 precursor 0.165 0.097
MMP2 MMP2, CLG4A: 72 kDa type IV collagenase precursor 0.165 0.088
CFB CFB, BF, BFD: Complement factor B precursor 0.165 0.859
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.165 0.148
MMP1 MMP1, CLG: Interstitial collagenase precursor 0.165 0.097
HP HP: Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta c 0.165 0.859
ANGPTL3 ANGPTL3, ANGPT5, UNQ153/PRO179: Angiopoietin-related protein 3 precursor 0.165 0.097
CFH CFH, HF, HF1, HF2: Complement factor H precursor 0.165 0.110
SFTPD SFTPD, PSPD, SFTP4: Pulmonary surfactant-associated protein D precursor 0.165 0.049
C4A C4A: Complement C4-A precursor 0.165 0.028
C8B C8B: Complement component C8 beta chain precursor 0.156 0.097
C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 0.156 0.088
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.156 0.123
SPON1 SPON1, KIAA0762, VSGP: Spondin-1 precursor 0.156 0.038
F7 F7: Coagulation factor VII precursor 0.156 1.37
F9 F9: Coagulation factor IX precursor 0.156 0.813
PROC PROC: Vitamin K-dependent protein C precursor 0.156 0.902
F10 F10: Coagulation factor X precursor 0.156 0.902
C6 C6: Complement component C6 precursor 0.156 0.088
F2 F2: Prothrombin precursor 0.156 0.902
C7 C7: Complement component C7 precursor 0.156 0.099
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.148 0.148
FGA N/A 0.148 0.097
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.148 0.046
PRG4 PRG4, MSF, SZP: Proteoglycan-4 precursor 0.148 0.044
MFAP4 MFAP4: Microfibril-associated glycoprotein 4 precursor 0.148 0.099
CPB2 CPB2: Carboxypeptidase B2 precursor 0.148 0.025
FGB FGB: Fibrinogen beta chain precursor [Contains: Fibrinopeptide B] 0.148 0.097
COL4A1 N/A 0.148 0.088
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.148 0.148
LAMA2 LAMA2: Uncharacterized protein LAMA2 0.148 0.088
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.148 0.088
TNC TNC, HXB: Tenascin precursor 0.148 0.088
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.148 0.088
KLK3 KLK3, APS: Prostate-specific antigen precursor 0.148 1.17
ALK ALK: ALK tyrosine kinase receptor precursor 0.148 0.056
FGL2 FGL2: Fibroleukin precursor 0.148 0.088
LPA LPA: Apolipoprotein(a) precursor 0.148 0.694
KLK1 KLK1: Kallikrein-1 precursor 0.148 0.770
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.148 0.075
COL18A1 N/A 0.148 0.075
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.148 0.050
PLG PLG: Plasminogen precursor 0.148 0.770
SPOCK1 SPOCK1, SPOCK, TIC1, TICN1: Testican-1 precursor 0.148 0.075
SLIT2 SLIT2, SLIL3: Slit homolog 2 protein precursor 0.148 0.171
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.148 1.17
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.148 0.078
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.148 0.088
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.148 0.099
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.148 0.029
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.148 0.099
BMP1 N/A 0.148 0.148
KLK6 KLK6, PRSS18, PRSS9: Kallikrein-6 precursor 0.148 2.94
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.109 0.032
SELE SELE, ELAM1: E-selectin precursor 0.109 0.065
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.109 0.065
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.109 0.561
MME MME, EPN: Neprilysin 0.109 0.029
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.109 0.033
SORL1 SORL1: Sortilin-related receptor precursor 0.109 0.081
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.109 0.126
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.081
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.109 0.081
EGF EGF: Pro-epidermal growth factor precursor 0.109 0.065
ITGB4 N/A 0.109 0.072
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.109 0.033
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.109 0.072
TMPRSS9 N/A 0.109 0.878
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.109 0.072
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, testis-specific isoform precursor 0.109 0.029
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.109 0.032
EDA N/A 0.109 0.049
DLK1 DLK1, DLK: Delta-like protein precursor 0.109 0.109
KEL KEL: Kell blood group glycoprotein 0.109 0.029
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.109 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.109 0.109
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.109 0.065
CD69 CD69: Early activation antigen CD69 0.109 0.029
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.109 0.044
AREG AREG, SDGF: Amphiregulin precursor 0.109 0.065
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.098 0.058
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.098 0.026
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.098 0.058
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.040
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.098 0.586
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.098 0.026
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.098 0.064
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.098 0.098
LDLR LDLR: Low-density lipoprotein receptor precursor 0.098 0.065
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.098 0.065
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.073
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.098 0.0264
HPN HPN, TMPRSS1: Serine protease hepsin 0.098 0.577
ITGB7 ITGB7: Integrin beta-7 precursor 0.098 0.058
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.098 0.044
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.098 0.064
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.098 0.098
ATRN N/A 0.098 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.098 0.036
MEP1A MEP1A: Meprin A subunit alpha precursor 0.098 0.073
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.098 0.040
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.098 0.065
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.098 0.065
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.098 0.577
JAG2 JAG2: Jagged-2 precursor 0.098 0.098
MEP1B MEP1B: Meprin A subunit beta precursor 0.098 0.064
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.083 0.028
ECM1 ECM1: Extracellular matrix protein 1 precursor 0.083 0.028
PTGDS PTGDS, PDS: Prostaglandin-H2 D-isomerase precursor 0.083 0.052
NULL A1BG: Alpha-1B-glycoprotein precursor 0.083 0.028
IFNG IFNG: Interferon gamma precursor 0.083 0.028
LOC643930 CCL3L1, D17S1718, G0S19-2, SCYA3L1: Small-inducible cytokine A3-like 1 precursor 0.083 0.028
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.083 0.144
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.083 0.028
IL4 IL4: Interleukin-4 precursor 0.083 0.028
OPTC OPTC, OPT: Opticin precursor 0.083 0.028
CCL26 CCL26, SCYA26, UNQ216/PRO242: Small-inducible cytokine A26 precursor 0.083 0.028
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.083 0.028
KITLG KITLG, MGF, SCF: Kit ligand precursor 0.083 0.028
THPO THPO, MGDF: Thrombopoietin precursor 0.083 0.028
APOE APOE: Apolipoprotein E precursor 0.083 0.026
MMRN2 MMRN2, EMILIN3: Multimerin-2 precursor 0.083 0.028
CCL15 CCL15, MIP5, NCC3, SCYA15: Small-inducible cytokine A15 precursor 0.083 0.028
C1QTNF4 C1QTNF4, CTRP4: Complement C1q tumor necrosis factor-related protein 4 precursor 0.083 0.028
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.083 0.028
CSF3 CSF3, GCSF: Granulocyte colony-stimulating factor precursor 0.083 0.028
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.083 0.028
DCN DCN: Decorin precursor 0.083 0.028
NDP NDP: Norrin precursor 0.083 0.052
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.083 0.028
FGF9 FGF9: Glia-activating factor precursor 0.083 0.063
CNTN1 CNTN1: Contactin-1 precursor 0.075 0.025
CNTN4 CNTN4: Contactin-4 precursor 0.075 0.025
APOD APOD: Apolipoprotein D precursor 0.075 0.029
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.075 0.029
PTGS1 PTGS1, COX1: Prostaglandin G/H synthase 1 precursor 0.0688 0.0688
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0688 0.031
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.0688 0.030
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.062 0.028
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.062 0.030
CD55 CD55, CR, DAF: Complement decay-accelerating factor precursor 0.056 0.030
MST1 MST1, D3F15S2, DNF15S2, HGFL: Hepatocyte growth factor-like protein precursor 0.051 0.617
CSPG5 N/A 0.051 0.051
ITGB1 ITGB1, FNRB, MDF2, MSK12: Integrin beta-1 precursor 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
MMRN1 MMRN1, ECM, EMILIN4, MMRN: Multimerin-1 precursor 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
ELTD1 ELTD1, RP11-143H12.1-002: EGF, latrophilin and seven transmembrane domain contai 0.051 0.051
KLKB1 N/A 0.051 0.617
COL4A2 COL4A2: Collagen alpha-2(IV) chain precursor [Contains: Canstatin] 0.051 0.051
PLAU PLAU: Urokinase-type plasminogen activator precursor 0.051 0.617
LTBP1 LTBP1: Latent-transforming growth factor beta-binding protein, isoform 1S precur 0.051 0.051
NRP1 NRP, NRP1, VEGF165R: Neuropilin-1 precursor 0.051 0.051
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.049 0.074
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.049 0.027
GP1BB GP1BB: Platelet glycoprotein Ib beta chain precursor 0.049 0.036
SLITRK5 SLITRK5, KIAA0918, LRRC11: SLIT and NTRK-like protein 5 precursor 0.049 0.074
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.049 0.109
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.046 0.046
TNN TNN: Tenascin-N precursor 0.046 0.030
EGFL4 MEGF8, C19orf49, EGFL4, KIAA0817: Multiple epidermal growth factor-like domains 0.046 0.053
PTPRZ1 N/A 0.044 0.066
PLAU Plasminogen activator, urokinase 0.028 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.028 0.028
ENPP2 N/A 0.028 0.078
NPY NPY: Neuropeptide Y precursor [Contains: Neuropeptide Y 0.028 0.032
DSP DSP: Desmoplakin 0.028 0.028
GUCA2A GUCA2A, GUCA2: Guanylin precursor 0.028 0.028
PCGF6 N/A 0.028 0.028
BDNF BDNF: Brain-derived neurotrophic factor precursor 0.028 0.026
CCL14 N/A 0.028 0.028
TUBGCP6 TUBGCP6, GCP6, KIAA1669: Gamma-tubulin complex component 6 0.028 0.028
NPPC NPPC, CNP2: C-type natriuretic peptide precursor [Contains: CNP-22; CNP-29; CNP- 0.028 0.026
ACCN3 ACCN3, ASIC3, SLNAC1, TNAC1: Amiloride-sensitive cation channel 3 0.028 0.028
PTHLH N/A 0.028 0.028
PTPNS1 N/A 0.028 0.052
CGN N/A 0.028 0.028
GRP Gastrin-releasing peptide 0.028 0.028
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.028 0.028
RNASE1 RNASE1, RIB1, RNS1: Ribonuclease pancreatic precursor 0.028 0.026
SEPP1 SEPP1, SELP: Selenoprotein P precursor 0.028 0.026
PLTP PLTP: Phospholipid transfer protein precursor 0.028 0.025
LECT1 LECT1, CHMI: Chondromodulin-1 precursor 0.028 0.028
CST3 CST3: Cystatin-C precursor 0.028 0.0425
IRF2BP2 IRF2BP2, RP4-781K5.1-002: Interferon regulatory factor 2-binding protein 2. 0.028 0.028
GHRL GHRL, MTLRP, UNQ524/PRO1066: Appetite-regulating hormone precursor 0.028 0.028
PCSK6 N/A 0.028 0.028
SCRIB N/A 0.028 0.025
CST4 CST4: Cystatin-S precursor 0.028 0.028
NOG NOG: Noggin precursor 0.028 0.028
CSF1 CSF1: Macrophage colony-stimulating factor 1 precursor 0.028 0.028
LNX1 N/A 0.028 0.028
HHIP HHIP, HIP, UNQ5825/PRO19644: Hedgehog-interacting protein precursor 0.027 0.027
HTRA4 HTRA4: Probable serine protease HTRA4 precursor 0.027 0.237
PAPPA2 PAPPA2, PLAC3: Pappalysin-2 precursor 0.027 0.027
KLK11 KLK11, PRSS20, UNQ649/PRO1279, TLSP: Kallikrein-11 precursor 0.027 0.157
LRP3 LRP3: Low-density lipoprotein receptor-related protein 3 precursor 0.027 0.060
PRSS23 PRSS23, ZSIG13, UNQ270/PRO307: Serine protease 23 precursor 0.027 0.157
CLEC14A CLEC14A, C14orf27, UNQ236/PRO269, EGFR5: C-type lectin domain family 14 member A 0.027 0.027
NETO1 N/A 0.027 0.027
ITLN2 ITLN2, UNQ2789/PRO7179: Intelectin-2 precursor 0.027 0.027
MMP17 MMP17, MT4MMP: Matrix metalloproteinase-17 precursor 0.027 0.044
HPR HPR: Haptoglobin-related protein precursor 0.027 0.174
MUC13 MUC13, DRCC1, UNQ6194/PRO20221, RECC: Mucin-13 precursor 0.027 0.027
CSPG3 CSPG3, NCAN, NEUR: Neurocan core protein precursor 0.027 0.027
PRSS36 PRSS36: Polyserase-2 precursor 0.027 0.265
GP2 GP2: Pancreatic secretory granule membrane major glycoprotein GP2 precursor 0.027 0.027
CTRC CTRC, CLCR: Chymotrypsin-C precursor 0.027 0.174
CR1L complement component (3b/4b) receptor 1-like 0.027 0.027
SEZ6L SEZ6L, KIAA0927, UNQ2542/PRO6094: Seizure 6-like protein precursor 0.027 0.067
TPSG1 TPSG1, PRSS31, TMT: Tryptase gamma precursor 0.027 0.197
PGM5 PGM5, PGMRP: Phosphoglucomutase-like protein 5 0.027 0.177
PRSS21 PRSS21, ESP1, UNQ266/PRO303, TEST1: Testisin precursor 0.027 0.265
FAM5C FAM5C, DBCCR1L, DBCCR1L1: Protein FAM5C precursor 0.027 0.083
MASP1 MASP1, CRARF, CRARF1, PRSS5: Complement-activating component of Ra-reactive fact 0.027 0.157
GZMK GZMK, TRYP2: Granzyme K precursor 0.027 0.157
HTRA1 HTRA1, HTRA, PRSS11: Serine protease HTRA1 precursor 0.027 0.491
CFC1 CFC1: Cryptic protein precursor 0.027 0.027
PRRG1 PRRG1, PRGP1, TMG1: Transmembrane gamma-carboxyglutamic acid protein 1 precursor 0.027 0.027
EDIL3 EDIL3, DEL1: EGF-like repeat and discoidin I-like domain-containing protein 3 pr 0.027 0.050
CNTNAP2 CNTNAP2, CASPR2, KIAA0868: Contactin-associated protein-like 2 precursor 0.027 0.083
ELA2A ELA2A: Elastase-2A precursor 0.027 0.265
GZMA GZMA, CTLA3, HFSP: Granzyme A precursor 0.027 0.174
KREMEN2 KREMEN2, KRM2: Kremen protein 2 precursor 0.027 0.027
NELL1 NELL1, NRP1: Protein kinase C-binding protein NELL1 precursor 0.027 0.067
NTNG2 N/A 0.027 0.027
CFHR3 CFHR3, CFHL3, FHR3: Complement factor H-related protein 3 precursor 0.027 0.027
PRRG2 PRRG2, PRGP2, TMG2: Transmembrane gamma-carboxyglutamic acid protein 2 precursor 0.027 0.027
KLK10 KLK10, NES1, PRSSL1: Kallikrein-10 precursor 0.027 0.157
TPSAB1 N/A 0.027 0.265
ACR ACR, ACRS: Acrosin precursor 0.027 0.174
GZMM GZMM, MET1: Granzyme M precursor 0.027 0.174
CTRB1 CTRB1, CTRB: Chymotrypsinogen B precursor 0.027 0.174
GZMH GZMH, CGL2, CTSGL2: Granzyme H precursor 0.027 0.174
KLK9 KLK9: Kallikrein-9 precursor 0.027 0.265
PLGLA1 PLGLA1, PLGP2: Plasminogen-related protein A precursor 0.027 0.027
CTRL CTRL, CTRL1: Chymotrypsin-like protease CTRL-1 precursor 0.027 0.174
ITLN1 ITLN1, INTL, UNQ640/PRO1270, ITLN, LFR: Intelectin-1 precursor 0.027 0.027
SCARF2 SCARF2, SREC2, SREPCR: Scavenger receptor class F member 2 precursor 0.027 0.027
NELL2 NELL2, NRP2: Protein kinase C-binding protein NELL2 precursor 0.027 0.027
PRSS27 PRSS27, MPN, UNQ1884/PRO4327: Serine protease 27 precursor 0.027 0.265
PRRG4 PRRG4, TMG4: Transmembrane gamma-carboxyglutamic acid protein 4 precursor 0.027 0.027
MASP2 MASP2: Mannan-binding lectin serine protease 2 precursor 0.027 0.265
NTN4 NTN4: Netrin-4 precursor 0.027 0.027
TSP50 TSP50: Testis-specific protease-like protein 50 precursor 0.027 0.176
LAMC2 LAMC2, LAMB2T, LAMNB2: Laminin subunit gamma-2 precursor 0.027 0.027
KLK12 KLK12, KLKL5, UNQ669/PRO1303: Kallikrein-12 precursor 0.027 0.265
ELA1 ELA1: Elastase-1 precursor 0.027 0.174
HABP2 HABP2, HGFAL, PHBP: Hyaluronan-binding protein 2 precursor 0.027 0.174
ATRN N/A 0.027 0.050
ELA3A ELA3A, ELA3: Elastase-3A precursor 0.027 0.174
PRSS2 PRSS2, TRY2, TRYP2: Trypsin-2 precursor 0.027 0.174
PRSS8 PRSS8: Prostasin precursor 0.027 0.157
UNC5D N/A 0.025 0.025
ITM2C ITM2C, BRI3, hucep-14, NPD018, PSEC0047: Integral membrane protein 2C 0.025 0.025
LOC641705 AMY2A: Pancreatic alpha-amylase precursor 0.025 0.025
TF TF, PRO1400: Serotransferrin precursor 0.025 0.029
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.025 0.063
CA11 CA11, CARP2, UNQ211/PRO237: Carbonic anhydrase-related protein 11 precursor 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.025
VNN1 VNN1: Pantetheinase precursor 0.025 0.025
2.15E-3
Total Score 1.01