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Evidence of Interaction Between PLK1 and PSMA3

The interaction score between PLK1 and PSMA3 is 200.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismPLK1 OrthologuePSMA3 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YMR001C 1 YOR362C 1
worm P34331 1 Q09583 1
worm Q9N2L7 0.33 Q09583 1
fly P52304 1 Q9V5C6 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in PLK1 and PSMA3:
Domains in PLK1Domains in PSMA3
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR000959 POLO box duplicated region
IPR001353 20S proteasome, A and B subunits
IPR000426 Proteasome alpha-subunit

The Chi square scores for co-occurrence of domains that are present in PLK1 and PSMA3 are listed below.

Domain 1Domain 2Chi Square
IPR000959 POLO box duplicated region IPR001353 20S proteasome, A and B subunits 1222.5
IPR000959 POLO box duplicated region IPR000426 Proteasome alpha-subunit 295.276
IPR002290 Serine/threonine protein kinase IPR001353 20S proteasome, A and B subunits 30.6917
IPR008271 Serine/threonine protein kinase, active site IPR001353 20S proteasome, A and B subunits 19.7897
IPR011009 Protein kinase-like IPR001353 20S proteasome, A and B subunits 12.4605
IPR002290 Serine/threonine protein kinase IPR000426 Proteasome alpha-subunit 6.34315
IPR000719 Protein kinase IPR001353 20S proteasome, A and B subunits 4.69912
IPR008271 Serine/threonine protein kinase, active site IPR000426 Proteasome alpha-subunit 3.35494
IPR011009 Protein kinase-like IPR000426 Proteasome alpha-subunit 1.52636
IPR000719 Protein kinase IPR000426 Proteasome alpha-subunit 0.0968492

The background colour of the table refers to:

  • Blue Domain is only present in PLK1
  • Yellow Domain is only present in PSMA3
  • Green Domain is present in both PLK1 and PSMA3

 0.980
Post-translational Modifications

Protein: PLK1

PTMResidueReference
Phosphorylation 87 PubMed, HPRD
Phosphorylation 210 PubMed, HPRD
Phosphorylation 326 PubMed, HPRD
Phosphoserine 137 PubMed, HPRD
Phosphoserine 335 HPRD
Phosphothreonine 210 HPRD

Protein: PSMA3

PTMResidueReference
Acetylation 2 PubMed, HPRD
N-acetylserine 1 HPRD
Phosphorylation 243 PubMed, HPRD
Phosphorylation 250 PubMed, HPRD
Phosphoserine 249 HPRD
Phosphotyrosine 160 HPRD
Localisation

Protein: PLK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: PSMA3

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PLK1 and PSMA3 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PLK1 andPSMA3. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PLK1 has 1428 interactors and PSMA3 has 1068 interactors of which there are 651 common interactors.

Common InteractorName of Common InteractorScore for PLK1-Interactor (?)Score for PSMA3-Interactor (?)
CDC25A CDC25A: M-phase inducer phosphatase 1 71.20 0.025
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 69.20 3.41E3
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 35.90 0.097
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 21.10 0.372
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 6.64 0.141
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 6.64 0.066
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 6.64 0.066
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 6.64 0.141
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 6.64 0.141
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 6.64 0.063
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 6.64 0.066
CDK2 CDK2: Cell division protein kinase 2 3.97 0.763
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 1.97 0.032
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 1.33 0.141
SNRPA SNRPA: U1 small nuclear ribonucleoprotein A 1.16 0.033
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.878 1.59E3
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.878 3.41E3
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.795 0.048
PSMB4 PSMB4: Proteasome subunit beta type-4 precursor 0.617 0.617
PSMA1 PSMA1, PROS30, PSC2: Proteasome subunit alpha type-1 0.217 2.91
PSMB5 PSMB5, LMPX: Proteasome subunit beta type-5 precursor 0.217 0.265
CTRL PSMB10, MECL1: Proteasome subunit beta type-10 precursor 0.217 0.824
PSMB1 PSMB1, PSC5: Proteasome subunit beta type-1 precursor 0.195 691.00
PSMA4 PSMA4, PSC9: Proteasome subunit alpha type-4 0.195 691.00
PSMB9 PSMB9, LMP2, RING12: Proteasome subunit beta type-9 precursor 0.195 31.70
PSMA7 PSMA7: Proteasome subunit alpha type-7 0.195 323.00
PSMA8 PSMA8, PSMA7L: Proteasome subunit alpha type-7-like 0.195 12.60
PSMB3 PSMB3: Proteasome subunit beta type-3 0.195 195.00
PSMA6 PSMA6, PROS27: Proteasome subunit alpha type-6 0.195 1.64E3
PSMB6 PSMB6, LMPY: Proteasome subunit beta type-6 precursor 0.195 195.00
PSMB2 PSMB2: Proteasome subunit beta type-2 0.195 691.00
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.165 0.0333
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.165 0.0425
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.165 0.157
ROCK1 ROCK1: Rho-associated protein kinase 1 0.165 0.416
PLEK PLEK, P47: Pleckstrin 0.165 0.0446
NF2 NF2, SCH: Merlin 0.165 0.028
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.165 0.026
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.165 0.0425
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.165 0.0446
CCNB1 Cyclin B1 0.148 0.040
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.148 0.040
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.148 0.066
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.148 0.029
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.025
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.148 0.032
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.148 0.088
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.148 0.275
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.148 0.040
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.148 0.046
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.025
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.148 0.275
ELMO1 N/A 0.148 0.025
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.148 0.032
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.025
MCM3 MCM3: DNA replication licensing factor MCM3 0.148 0.141
SOS1 SOS1: Son of sevenless homolog 1 0.148 0.067
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.075
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.148 0.078
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.148 0.040
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
DOK1 DOK1: Docking protein 1 0.148 0.046
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.148 0.275
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.137 0.154
MAP2K5 N/A 0.109 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.083
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.028
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.109 0.026
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.028
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.028
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.109 0.032
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.028
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.109 0.127
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.083
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.109 0.087
PSCD2 N/A 0.109 0.028
VASP VASP: Vasodilator-stimulated phosphoprotein 0.109 0.0425
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.109 0.062
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.109 0.096
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.028
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.109 0.109
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.109 0.026
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.109 0.155
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.109 0.052
BMX N/A 0.109 0.055
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.109 0.032
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.028
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.098 0.114
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.098 0.099
RDX RDX: Radixin 0.098 0.029
JAK1 0.098 0.114
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.098 0.075
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.098 0.063
VAV1 VAV1, VAV: Proto-oncogene vav 0.098 0.046
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.098 0.114
STAT6 STAT6: Signal transducer and activator of transcription 6 0.098 0.063
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.098 0.056
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.098 0.069
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.098 0.038
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.098 0.025
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.098 0.063
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.098 0.069
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.098 0.233
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.098 0.372
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.098 0.046
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.098 0.056
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.025
SYK SYK: Tyrosine-protein kinase SYK 0.098 0.139
CRKL CRKL: Crk-like protein 0.098 0.078
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.098 0.029
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.098 0.099
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.098 0.086
LYN LYN: Tyrosine-protein kinase Lyn 0.098 0.114
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.025
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.098 0.025
MSN MSN: Moesin 0.098 0.046
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.098 0.233
PLD1 PLD1: Phospholipase D1 0.098 0.063
CSK CSK: Tyrosine-protein kinase CSK 0.098 0.233
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.098 0.056
ARHGEF7 N/A 0.098 0.025
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.098 0.029
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.098 0.225
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.098 0.063
STAT3 0.098 0.025
NCK2 NCK2: Cytoplasmic protein NCK2 0.098 0.029
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.098 0.029
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.098 0.075
APS SH2B2, APS: SH2B adapter protein 2 0.098 0.029
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.098 0.275
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.098 0.046
VIL2 N/A 0.098 0.046
STMN1 STMN1, LAP18, OP18: Stathmin 0.098 0.038
PSCD4 PSCD4, CYT4: Cytohesin-4 0.098 0.038
HCK N/A 0.098 0.069
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.098 0.025
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.025
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.083 0.0446
STK16 N/A 0.083 0.307
CDKL5 N/A 0.083 0.110
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.083 0.109
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.083 0.100
DAPK2 DAPK2: Death-associated protein kinase 2 0.083 0.109
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.083 0.123
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.083 0.152
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.083 0.251
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.083 0.087
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.083 0.166
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.083 0.032
MAPKAPK5 N/A 0.083 0.165
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.083 0.052
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.083 0.191
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.083 0.191
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.083 0.515
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.083 0.191
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.083 0.210
MAPK15 N/A 0.083 0.165
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.083 0.109
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.165
ARFGAP1 N/A 0.083 0.036
PRKAA1 N/A 0.083 0.152
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.165
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.083 0.152
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.083 0.307
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.083 0.0446
ELF1 ELF1: ETS-related transcription factor Elf-1 0.083 0.036
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.083 0.852
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.083 0.251
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.165
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.083 0.052
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.083 0.0446
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.165
RB1 RB1: Retinoblastoma-associated protein 0.083 0.0446
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.083 0.027
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.083 0.077
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.083 0.251
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.083 1.81
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.165
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.083 0.123
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.083 0.251
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.083 0.251
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.075 0.171
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.075 0.099
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.075 0.136
DYRK3 N/A 0.075 0.111
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.148
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.075 0.099
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.148
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.075 0.136
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.148
MDN1 MDN1, KIAA0301: Midasin 0.075 0.063
RPS6KB1 N/A 0.075 0.461
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.075 0.275
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.075 0.372
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.075 0.078
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.075 0.040
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.075 0.097
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.075 1.62
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.075 0.040
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.148
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.075 0.040
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.148
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.075 0.111
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.075 0.136
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.275
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.075 0.111
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.075 0.503
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.075 0.171
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.075 0.372
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.075 0.171
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.075 0.372
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.075 0.171
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.075 0.372
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.148
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.098
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.098
MYO3A MYO3A: Myosin IIIA 0.075 0.099
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.075 0.078
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.075 0.063
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.075 0.372
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.075 0.136
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.075 0.141
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.075 0.066
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.075 0.461
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.763
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.075 0.097
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.075 0.275
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.075 0.111
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.075 0.078
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.075 0.225
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.075 0.099
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.075 0.029
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.763
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.075 0.461
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.148
CDK4 CDK4: Cell division protein kinase 4 0.075 0.763
NPM1 NPM1, NPM: Nucleophosmin 0.075 0.141
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.075 0.099
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.075 0.275
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.075 0.225
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.075 0.225
STK10 STK10: Uncharacterized protein STK10 0.075 0.225
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.075 0.461
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.075 0.372
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.075 0.275
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.075 0.040
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.148
WEE1 WEE1: Wee1-like protein kinase 0.075 0.372
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.075 0.275
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.075 0.040
FNBP1 N/A 0.075 0.078
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.075 0.097
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.075 0.032
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.075 0.078
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.075 0.763
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.075 0.069
GIT2 N/A 0.075 0.025
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.075 0.136
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.075 0.225
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.075 0.097
CDK7 CDK7, MO15: Cell division protein kinase 7 0.075 0.763
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.075 0.088
CDK6 CDK6: Cell division protein kinase 6 0.075 0.136
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.075 0.225
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.075 0.099
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.075 0.461
CXorf9 N/A 0.075 0.063
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.148
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.075 0.141
ATM ATM: Serine-protein kinase ATM 0.075 0.086
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.075 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.148
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.075 0.086
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.148
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.075 0.275
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.075 0.097
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.075 0.136
CDK5 CDK5: Cell division protein kinase 5 0.075 0.171
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.075 0.097
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.148
CDC20 CDC20: Cell division cycle protein 20 homolog 0.075 0.040
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.075 0.088
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.075 0.171
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.148
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.075 0.139
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.148
PTMA N/A 0.052 0.074
NBN NBN, NBS, NBS1, P95: Nibrin 0.052 0.157
MKI67 MKI67: Antigen KI-67 0.052 0.0446
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.049 0.026
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.049 0.028
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.028
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.049 0.307
AMPH AMPH, AMPH1: Amphiphysin 0.049 0.028
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.049 0.0425
SRPR SRPR: Uncharacterized protein SRPR 0.049 0.087
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.165
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.049 0.032
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.049 0.028
LIMK2 LIMK2: LIM domain kinase 2 0.049 0.191
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.049 0.032
CASP9 CASP9, MCH6: Caspase-9 precursor 0.049 0.028
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.049 0.0425
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.049 0.052
CIITA CIITA, MHC2TA: MHC class II transactivator 0.049 0.052
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.028
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.049 0.070
PPP1R8 N/A 0.047 0.066
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.044 0.063
CD2AP CD2AP: CD2-associated protein 0.044 0.129
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.044 0.046
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.044 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.044 0.025
SEC24B SEC24B: Protein transport protein Sec24B 0.044 0.063
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.044 0.025
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.044 0.025
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.044 0.046
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.044 0.276
TSC2 TSC2, TSC4: Tuberin 0.044 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.025
GMIP GMIP: GEM-interacting protein 0.044 0.029
SNX3 N/A 0.044 0.025
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.044 0.029
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.044 0.276
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.044 0.171
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.044 0.075
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.097
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.044 0.063
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.044 0.129
CTPS CTPS: CTP synthase 1 0.044 0.276
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.044 0.025
STAM2 STAM2: Signal transducing adapter molecule 2 0.044 0.029
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.044 0.129
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.044 0.129
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.044 0.063
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.044 0.063
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.044 0.025
THOC1 THOC1, HPR1: THO complex subunit 1 0.044 0.063
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.044 0.025
CNN2 CNN2: Calponin-2 0.044 0.025
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.044 0.171
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.044 0.049
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.097
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.044 0.225
RPS10 RPS10: 40S ribosomal protein S10 0.044 0.078
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.044 0.129
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.044 0.078
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.029
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.044 0.111
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.044 0.038
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.044 0.129
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.044 0.078
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.044 0.029
HSP90AA1 Hsp89-alpha-delta-N 0.044 0.078
VCP VCP: Transitional endoplasmic reticulum ATPase 0.044 0.129
WASPIP N/A 0.044 0.063
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.04 0.070
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.04 0.032
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.04 0.070
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.028
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.036 0.063
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.036 0.046
NRAS NRAS, HRAS1: GTPase NRas precursor 0.036 0.129
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.036 0.063
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.036 0.078
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.036 0.038
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.036 0.063
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.036 0.025
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.036 0.276
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.036 0.046
RAB5B RAB5B: Ras-related protein Rab-5B 0.036 0.025
GHR GHR: Growth hormone receptor precursor 0.034 0.036
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.034 0.027
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.034 0.036
CD44 N/A 0.034 0.027
FADD FADD, MORT1: Protein FADD 0.034 0.0446
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.030 0.026
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.030 0.041
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.030 0.033
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.030 0.040
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.030 0.098
KIT KIT: Mast/stem cell growth factor receptor precursor 0.030 0.033
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.030 0.029
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.030 0.073
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.030 0.090
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.030 0.026
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.030 0.026
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.030 0.029
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.030 0.033
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.030 0.026
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.030 0.114
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.030 0.051
PSMB8 PSMB8, LMP7, RING10, Y2: Proteasome subunit beta type-8 precursor 0.0288 0.0288
IFI16 N/A 0.028 0.074
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.028 0.0446
ABCF1 N/A 0.028 0.144
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.028 0.032
ZNF267 ZNF267: Zinc finger protein 267 0.028 0.036
API5 N/A 0.028 0.087
AFF1 N/A 0.028 0.027
RBM6 RBM6, DEF3: RNA-binding protein 6 0.028 0.027
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.028 0.036
MARK2 N/A 0.028 0.0425
KIF23 N/A 0.028 0.036
TOP2B N/A 0.028 0.0446
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
TCOF1 N/A 0.028 0.074
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.028 0.036
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.028 0.070
TGIF2 TGIF2: Homeobox protein TGIF2 0.028 0.0446
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.028 0.0446
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.028 0.0425
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.028 0.027
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.028 0.074
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.028 0.157
TRRAP N/A 0.028 0.052
IRF3 IRF3: Interferon regulatory factor 3 0.028 0.036
GTF2F2 N/A 0.028 0.027
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.028 0.157
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.028 0.070
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.028 0.027
GNB2L1 Lung cancer oncogene 7 0.028 0.0446
SP100 N/A 0.028 0.036
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.028 0.074
UBAP2 N/A 0.028 0.070
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.028 0.036
NCOA3 N/A 0.028 0.0446
ESPL1 N/A 0.028 0.144
CENPA CENPA: Histone H3-like centromeric protein A 0.028 0.074
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.028 0.062
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.028 0.074
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.028 0.036
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.028 0.027
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.028 0.032
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.028 0.087
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.028 0.0446
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.028 0.0446
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.028 0.036
XRCC1 XRCC1: DNA-repair protein XRCC1 0.028 0.036
SET SET: Protein SET 0.028 0.074
PHLDB2 N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
CHUK N/A 0.028 0.070
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.028 0.036
SREBF2 N/A 0.028 0.0446
DNMT1 DNMT1, AIM, DNMT: DNA 0.028 0.0446
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.028 0.074
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPEF1 N/A 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
KIAA0853 N/A 0.028 0.036
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.028 0.070
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.028 0.0446
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.028 0.036
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.028 0.307
RBM14 RBM14, SIP: RNA-binding protein 14 0.028 0.0446
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.028 0.032
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.028 0.036
WDR1 N/A 0.028 0.0446
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.028 0.0446
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.028 0.0446
DDX21 DDX21: Nucleolar RNA helicase 2 0.028 0.157
SAT SAT1, SAT: Diamine acetyltransferase 1 0.028 0.0425
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.028 0.074
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.028 0.0425
MATR3 MATR3, KIAA0723: Matrin-3 0.028 0.074
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.028 0.027
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.028 0.0446
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.028 0.087
NULL RcPSMB3 (Fragment) 0.0258 1.37
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.025 0.046
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
NIPBL N/A 0.025 0.025
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.025 0.046
FKBP4 FKBP4: FK506-binding protein 4 0.025 0.038
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.025 0.032
NUP153 N/A 0.025 0.066
MYH9 MYH9: Myosin-9 0.025 0.032
MTA1 MTA1: Metastasis-associated protein MTA1 0.025 0.040
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.025 0.038
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.025 0.066
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.025 1.77
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.025 0.040
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.025 0.032
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.025 0.066
COPE COPE: Coatomer subunit epsilon 0.025 0.063
RBM7 0.025 0.040
HDAC3 HDAC3: Histone deacetylase 3 0.025 0.066
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.025 0.066
ARMET ARMET, ARP: Protein ARMET precursor 0.025 0.032
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.025 0.040
SAPS3 N/A 0.025 0.063
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.025 0.066
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.025 0.029
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.025 0.032
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.025 0.066
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.025 1.50
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.025 0.141
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.025 0.040
KLHDC4 N/A 0.025 0.046
CBX3 CBX3: Chromobox protein homolog 3 0.025 0.141
TP53 TP53, P53: Cellular tumor antigen p53 0.025 0.141
COPB2 COPB2: Coatomer subunit beta' 0.025 10.50
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.025 0.066
SSB SSB: Lupus La protein 0.025 0.141
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.025 0.066
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.025 0.066
PCNA PCNA: Proliferating cell nuclear antigen 0.025 0.066
AIP AIP, XAP2: AH receptor-interacting protein 0.025 0.046
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.025 0.038
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.025 0.141
GRK6 N/A 0.025 0.025
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.025 0.066
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.025 0.040
CAMKK1 N/A 0.025 0.025
CORO1C CORO1C, CRNN4: Coronin-1C 0.025 0.040
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.025 0.038
CAMK2A N/A 0.025 0.025
WBSCR20A N/A 0.025 0.032
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.025 0.141
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.025 0.040
CUL5 CUL5, VACM1: Cullin-5 0.025 0.032
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.025 0.066
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.025 0.063
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.025 0.038
COPA COPA: Coatomer subunit alpha 0.025 0.078
SEC31L1 N/A 0.025 0.040
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.025 0.038
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.025 0.650
BRPF1 BRPF1, BR140: Peregrin 0.025 0.029
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.025 0.040
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.025 0.032
DYNC1I2 N/A 0.025 0.029
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.025 0.141
TIAL1 TIAL1: Nucleolysin TIAR 0.025 0.066
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.025 0.066
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.025 0.030
SP3 SP3: Transcription factor Sp3 0.025 0.032
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.025 0.032
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.025 0.038
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.025 0.066
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.025 0.063
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.025 0.032
KIF11 N/A 0.025 0.066
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.025 0.066
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.025 0.066
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.025 0.032
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.025 0.040
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.025 0.063
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.025 0.066
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.025 0.046
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.025 0.032
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.025 0.040
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.025 0.046
NUP98 N/A 0.025 3.39
LIG1 LIG1: DNA ligase 1 0.025 0.040
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.025 0.032
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.025 0.141
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.025 0.038
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.025 0.030
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.025 0.066
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.025 0.129
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.025 0.063
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.025 0.040
GSK3B N/A 0.025 0.046
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.025 0.040
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.025 0.032
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.025 0.040
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.025 0.032
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.025 0.066
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.025 0.114
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.025 0.032
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.025 0.040
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.025 0.040
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.025 0.032
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.025 0.141
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.025 0.038
KIAA1012 KIAA1012: Protein TRS85 homolog 0.025 0.063
HDAC2 HDAC2: Histone deacetylase 2 0.025 0.066
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.025 0.275
MYBL2 MYBL2, BMYB: Myb-related protein B 0.025 0.040
PRKCB1 N/A 0.025 0.025
SRF SRF: Serum response factor 0.025 0.040
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
MAP2K3 N/A 0.025 0.025
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.025 0.040
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.025 0.038
ADK ADK: Adenosine kinase 0.025 0.025
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.025 0.029
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.025 0.032
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.025 0.040
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.025 0.066
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.025 0.141
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.025 0.141
BCOR N/A 0.025 0.025
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.025 0.032
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.025 0.078
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.025 0.129
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.025 0.032
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.025 0.040
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.025 0.066
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.025 0.066
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.025 0.129
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.025 0.038
POLA2 POLA2: DNA polymerase subunit alpha B 0.025 0.141
UNG N/A 0.025 0.040
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.025 0.046
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.025 0.066
DIAPH1 Diaphanous 1 0.025 0.063
CUL4B N/A 0.025 0.032
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.025 0.032
YY1 YY1: Transcriptional repressor protein YY1 0.025 0.040
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.025 0.066
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.025 0.032
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.025 0.141
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.025 0.032
SYMPK SYMPK, SPK: Symplekin 0.025 0.046
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.025 0.078
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.025 0.066
NOL1 N/A 0.025 0.066
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.025 0.078
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.025 0.078
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.025 0.066
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.025 0.066
H2AFX H2AFX, H2AX: Histone H2A.x 0.025 0.040
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.025 0.032
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.025 0.141
CSDA CSDA, DBPA: DNA-binding protein A 0.025 0.029
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.025 0.032
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.025 0.046
0.572
Total Score 200.00