PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between PCNA and LIG1

The interaction score between PCNA and LIG1 is 63.10.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between PCNA and LIG1 = 0.83

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.027

Orthology

Organism	PCNA Orthologue		LIG1 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
bakers yeast	YBR088C	1	YDL164C	1	Immunoprecipitation AffinityCaptureMS Get References From PubMed
worm	O02115	1	Q27474	1
fly	P17917	1	Q960P4	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.593

Domains

No domains were used in calculating likelihood of interaction

0.028

Post-translational Modifications

Protein: PCNA

PTM	Residue	Reference
Ubiquitination	164	PubMed, HPRD

Protein: LIG1

PTM	Residue	Reference
Phosphorylation	66	PubMed, HPRD
Phosphorylation	76	PubMed, HPRD
Phosphorylation	141	PubMed, HPRD
Phosphorylation	195	PubMed, HPRD
Phosphorylation	911	PubMed, HPRD
Phosphoserine	66	HPRD
Phosphoserine	76	HPRD
Phosphoserine	141	HPRD
Phosphoserine	911	HPRD
Phosphothreonine	195	HPRD

Localisation

Protein: PCNA

Localisation	Reference
Nucleus	HPRD
Nucleolus	HPRD
Cytoplasm	HPRD

Protein: LIG1

Localisation	Reference
Nucleus	HPRD
Nucleoplasm	HPRD

Transitive Score

The common interactors between PCNA and LIG1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PCNA andLIG1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PCNA has 851 interactors and LIG1 has 892 interactors of which there are 705 common interactors.

Common Interactor	Name of Common Interactor	Score for PCNA-Interactor (?)	Score for LIG1-Interactor (?)
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	73.00	0.276
FEN1	FEN1, RAD2: Flap endonuclease 1	38.00	12.60
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	37.30	0.141
CSNK2A1	CSNK2A1: CSNK2A1 protein	34.20	0.078
UNG	N/A	34.20	0.129
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	34.20	0.129
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	16.60	0.078
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	10.50	0.066
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	1.97	0.029
MCM3	MCM3: DNA replication licensing factor MCM3	1.62	0.276
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	1.62	0.129
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	1.07	0.066
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.923	0.307
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.827	0.129
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.827	0.276
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.827	0.276
KIF11	N/A	0.827	0.276
CCNB1	Cyclin B1	0.822	0.129
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.763	0.129
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.763	0.129
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.763	0.129
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.763	0.078
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.763	0.129
TP53	TP53, P53: Cellular tumor antigen p53	0.704	0.078
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.461	0.063
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.423	0.066
NBN	NBN, NBS, NBS1, P95: Nibrin	0.416	0.087
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.393	0.704
ESPL1	N/A	0.307	0.307
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.307	0.144
CENPA	CENPA: Histone H3-like centromeric protein A	0.307	0.144
MKI67	MKI67: Antigen KI-67	0.307	0.144
XRCC1	XRCC1: DNA-repair protein XRCC1	0.307	0.052
TRIP13	TRIP13: Thyroid receptor-interacting protein 13	0.304	0.040
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.304	0.032
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.304	0.032
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.276	0.129
MYBL2	MYBL2, BMYB: Myb-related protein B	0.276	0.129
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.276	0.276
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.276	0.276
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.276
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.276	0.129
H2AFX	H2AFX, H2AX: Histone H2A.x	0.276	0.129
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.276	0.129
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.276	0.078
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.276	0.276
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.276	0.129
CDC20	CDC20: Cell division cycle protein 20 homolog	0.276	0.129
CDK2	CDK2: Cell division protein kinase 2	0.276	0.129
MDN1	MDN1, KIAA0301: Midasin	0.275	0.078
RB1	RB1: Retinoblastoma-associated protein	0.260	0.087
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.254	0.046
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.254	0.046
EP300	N/A	0.254	0.046
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.251	0.052
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.245	0.032
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.191	0.0425
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.188	0.063
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.171	0.029
GMNN	GMNN: Geminin	0.160	0.025
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.157	0.074
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.144	0.307
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.144	0.307
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.144	0.144
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.144	0.307
KIF23	N/A	0.144	0.087
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.141	0.066
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.137	0.025
POLB	POLB: DNA polymerase beta	0.136	0.029
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.129
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.129	0.078
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.129	0.078
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.129	0.129
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.129	0.276
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.129	0.129
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.129
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.129	0.276
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.129
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.129
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.129	0.129
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.129	0.129
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.129	0.129
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.129
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.129	0.129
SNRPA	SNRPA: U1 small nuclear ribonucleoprotein A	0.129	0.048
NUP153	N/A	0.129	0.129
CBX3	CBX3: Chromobox protein homolog 3	0.129	0.276
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.129	0.129
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.129	0.129
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.129	0.078
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.129
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.129
CDK4	CDK4: Cell division protein kinase 4	0.129	0.129
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.129	0.276
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.129	0.129
POLA2	POLA2: DNA polymerase subunit alpha B	0.129	0.129
SSB	SSB: Lupus La protein	0.129	0.129
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.129
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.129	0.129
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.129	0.129
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.126	0.046
SET	SET: Protein SET	0.087	0.144
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.087	0.144
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.087	0.144
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.087	0.087
UBAP2	N/A	0.087	0.144
RBM14	RBM14, SIP: RNA-binding protein 14	0.087	0.144
TCOF1	N/A	0.087	0.144
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.087	0.307
DDX21	DDX21: Nucleolar RNA helicase 2	0.087	0.087
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.087	0.144
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.087	0.144
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.087	0.144
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.087	0.087
DNMT1	DNMT1, AIM, DNMT: DNA	0.087	0.307
PTMA	N/A	0.087	0.144
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.087	0.144
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.087	0.087
ABCF1	N/A	0.087	0.087
CCNH	CCNH: Cyclin-H	0.086	0.029
KIAA0101	PAF, KIAA0101, L5, NS5ATP9: PCNA-associated factor	0.082	0.027
C18orf56	N/A	0.082	0.027
SMC4L1	N/A	0.082	0.027
ZWINT	N/A	0.082	0.027
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.078	0.129
WEE1	WEE1: Wee1-like protein kinase	0.078	0.129
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.078	0.063
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.078	0.129
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.078	0.078
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.078	0.129
NOL1	N/A	0.078	0.129
PHF10	N/A	0.078	0.078
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.078	0.063
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.078	0.063
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.078	0.063
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.078	0.129
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.078	0.063
YY1	YY1: Transcriptional repressor protein YY1	0.078	0.078
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.078	0.063
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.078
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.078	0.129
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.078
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.078	0.129
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.078	0.129
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.078	0.078
HDAC2	HDAC2: Histone deacetylase 2	0.078	0.078
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.078
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.078	0.078
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.078	0.129
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.078	0.129
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.078	0.129
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.078	0.078
TIAL1	TIAL1: Nucleolysin TIAR	0.078	0.129
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.078
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.075	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.075	0.025
CCNT2	CCNT2: Cyclin-T2	0.075	0.025
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.075	0.025
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.074
KIAA0853	N/A	0.070	0.070
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.070	0.070
TOP2B	N/A	0.070	0.087
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.070
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.070	0.070
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.070	0.087
MATR3	MATR3, KIAA0723: Matrin-3	0.070	0.087
API5	N/A	0.070	0.070
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.070	0.087
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.070	0.052
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.070	0.087
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.070	0.052
SREBF2	N/A	0.070	0.070
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.070
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.070	0.070
MYB	MYB: Myb proto-oncogene protein	0.070	0.070
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.069	0.029
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.066	0.040
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.066	0.040
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.066	0.141
TK1	TK1: Thymidine kinase, cytosolic	0.066	0.066
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.066	0.066
HSPD1		0.066	0.066
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.066	0.040
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.066
MTHFD1	MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic	0.066	0.040
CTPS	CTPS: CTP synthase 1	0.066	0.066
HSP90AA1	Hsp89-alpha-delta-N	0.066	0.040
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.066	0.066
XPO1	XPO1, CRM1: Exportin-1	0.066	0.066
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.066
CDC23	CDC23: Cell division cycle protein 23 homolog	0.066	0.066
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.063	0.063
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.063	0.129
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.063	0.078
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.063	0.078
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.063	0.129
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.063	0.078
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.063	0.078
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.063	0.078
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.063	0.063
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.063	0.078
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.063	0.063
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.063	0.129
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.063
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.063	0.063
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.063	0.046
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.063
PPP1R8	N/A	0.063	0.078
TAL1	TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1	0.063	0.046
MTA1	MTA1: Metastasis-associated protein MTA1	0.063	0.078
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.063	0.078
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.063	0.078
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.063	0.078
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.063	0.046
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.063	0.078
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.063	0.078
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.063	0.063
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.063	0.046
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.056	0.029
TPX2	TPX2, C20orf1, C20orf2, DIL2, HCA519: Targeting protein for Xklp2	0.053	0.053
PTGES3	PTGES3, P23, TEBP: Prostaglandin E synthase 3	0.053	0.025
TACC3	TACC3, ERIC1: Transforming acidic coiled-coil-containing protein 3	0.053	0.025
GTSE1	GTSE1: G2 and S phase-expressed protein 1	0.053	0.025
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.052	0.070
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.052	0.0425
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.052	0.070
CHUK	N/A	0.052	0.070
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.052	0.052
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.052	0.052
ARFGAP1	N/A	0.052	0.070
AFF1	N/A	0.052	0.052
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.052	0.0425
TRRAP	N/A	0.052	0.087
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.052	0.070
TGIF2	TGIF2: Homeobox protein TGIF2	0.052	0.070
GNB2L1	Lung cancer oncogene 7	0.052	0.087
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.052	0.070
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.052	0.070
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.052	0.070
DKC1	DKC1, NOLA4: H/ACA ribonucleoprotein complex subunit 4	0.0479	0.0479
SLBP	SLBP, HBP: Histone RNA hairpin-binding protein	0.0479	0.0479
KNTC2	KNTC2, HEC, HEC1: Kinetochore protein Hec1	0.0479	0.0479
PA2G4	PA2G4, EBP1: Proliferation-associated protein 2G4	0.0479	0.0479
EZH2	EZH2: Enhancer of zeste homolog 2	0.0479	0.0479
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.046	0.078
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.046	0.078
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.046	0.046
CSDA	CSDA, DBPA: DNA-binding protein A	0.046	0.046
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.046	0.063
RPS6KB1	N/A	0.046	0.046
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.046	0.063
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.046	0.078
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.046	0.046
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.046	0.063
FKBP4	FKBP4: FK506-binding protein 4	0.046	0.046
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.046	0.063
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.046	0.063
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.046	0.063
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.046	0.038
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.046	0.046
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.046	0.046
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.046	0.063
CDK7	CDK7, MO15: Cell division protein kinase 7	0.046	0.046
RUNX1	N/A	0.046	0.046
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.046	0.078
RBM7		0.046	0.046
COPB2	COPB2: Coatomer subunit beta'	0.046	0.046
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.046	0.046
CUL5	CUL5, VACM1: Cullin-5	0.046	0.063
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.046	0.063
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.046	0.078
WDR79	N/A	0.046	0.046
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.046	0.063
SRF	SRF: Serum response factor	0.046	0.046
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.046	0.078
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.046	0.063
MAFG	MAFG: Transcription factor MafG	0.046	0.038
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.046	0.063
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.046	0.078
SP3	SP3: Transcription factor Sp3	0.046	0.046
EEF2	EEF2, EF2: Elongation factor 2	0.045	0.032
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.0446	0.0446
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.0446	0.0446
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.0446
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.0446	0.036
ELF1	ELF1: ETS-related transcription factor Elf-1	0.0425	0.070
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.0425	0.0425
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.0425	0.052
EMD	EMD, EDMD, STA: Emerin	0.0425	0.052
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.0425	0.087
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.0425	0.070
SP100	N/A	0.0425	0.052
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.0425	0.032
WDR1	N/A	0.0425	0.0425
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.0425	0.070
COIL	COIL, CLN80: Coilin	0.0425	0.0425
SMARCC2	N/A	0.0425	0.052
GTF2F2	N/A	0.0425	0.0425
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.0425	0.052
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.0425	0.070
ZNF267	ZNF267: Zinc finger protein 267	0.0425	0.0425
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.0425	0.052
IFI16	N/A	0.0425	0.052
H1FX	H1FX: Histone H1x	0.0425	0.0425
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.0425	0.251
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.0425	0.052
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.040	0.040
CCT8	CCT8: Uncharacterized protein CCT8	0.040	0.066
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.040	0.066
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.040	0.032
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.040	0.040
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.040	0.040
LDHB	LDHB: L-lactate dehydrogenase B chain	0.040	0.066
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.040	0.032
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.040	0.040
THOC1	THOC1, HPR1: THO complex subunit 1	0.040	0.040
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.040
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.040	0.040
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.040	0.040
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.040	0.066
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.040	0.040
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.040	0.040
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.040	0.032
HNRPK	N/A	0.040	0.040
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.040	0.040
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.038	0.038
CRSP2	MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol	0.038	0.038
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.038	0.038
SAPS3	N/A	0.038	0.063
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.038	0.046
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.038	0.046
KIAA1012	KIAA1012: Protein TRS85 homolog	0.038	0.046
SOX4	SOX4: Transcription factor SOX-4	0.038	0.038
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.038	0.046
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.038	0.046
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.038	0.063
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.038	0.063
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.038	0.046
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.038	0.063
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.038	0.046
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.038	0.046
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.038	0.063
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.038	0.046
CORO1C	CORO1C, CRNN4: Coronin-1C	0.038	0.029
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.038	0.038
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.038	0.046
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.038	0.038
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.038	0.038
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.038	0.038
MYH9	MYH9: Myosin-9	0.038	0.038
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.038	0.046
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.038	0.046
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.038
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.038	0.046
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.038	0.046
COPE	COPE: Coatomer subunit epsilon	0.038	0.038
FZR1	N/A	0.038	0.038
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.038	0.063
GSK3B	N/A	0.038	0.029
COPA	COPA: Coatomer subunit alpha	0.038	0.038
KLHDC4	N/A	0.038	0.046
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.038	0.038
FNBP1	N/A	0.038	0.087
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.038	0.046
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.038	0.046
DIAPH1	Diaphanous 1	0.038	0.046
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.038	0.046
SEC31L1	N/A	0.038	0.038
SYMPK	SYMPK, SPK: Symplekin	0.038	0.046
RANBP9	RANBP9, RANBPM: Ran-binding protein 9	0.038	0.038
WBSCR20A	N/A	0.038	0.078
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.038	0.063
TOP3A	TOP3A, TOP3: DNA topoisomerase 3-alpha	0.038	0.046
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.038	0.029
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.038	0.063
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.038	0.078
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.038	0.038
PCAF	PCAF: Histone acetyltransferase PCAF	0.038	0.038
FUBP1	N/A	0.036	0.074
YWHAQ	YWHAQ: 14-3-3 protein theta	0.036	0.036
PHB2	PHB2, BAP, REA: Prohibitin-2	0.036	0.0446
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.032	0.032
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.032
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.032	0.052
XRCC4	N/A	0.032	0.032
NCOA3	N/A	0.032	0.052
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.032	0.0425
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.032	0.032
ERG	ERG: Transcriptional regulator ERG	0.032	0.0425
RBM6	RBM6, DEF3: RNA-binding protein 6	0.032	0.070
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.032	0.0425
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.032	0.032
ROCK1	ROCK1: Rho-associated protein kinase 1	0.032	0.127
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.032	0.026
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.032	0.032
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.032	0.032
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.032	0.0425
IRF3	IRF3: Interferon regulatory factor 3	0.032	0.070
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.032	0.0425
PLEK	PLEK, P47: Pleckstrin	0.032	0.127
HIVEP1	N/A	0.032	0.052
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.032	0.032
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.032	0.032
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.032	0.032
FRG1	FRG1: Protein FRG1	0.032	0.040
CASP3	CASP3, CPP32: Caspase-3 precursor	0.032	0.040
CD2AP	CD2AP: CD2-associated protein	0.032	0.112
THOP1	THOP1: Thimet oligopeptidase	0.032	0.032
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.032	0.066
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.032	0.066
CRKL	CRKL: Crk-like protein	0.032	0.090
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.032	0.040
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.032	0.040
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.032	0.032
PPARBP	N/A	0.032	0.032
QARS	QARS: Glutaminyl-tRNA synthetase	0.032	0.040
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.032	0.032
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.032	0.040
PPID	PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase	0.032	0.032
ME2	ME2: NAD-dependent malic enzyme, mitochondrial precursor	0.032	0.040
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.029	0.139
ZNF551	N/A	0.029	0.038
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.029	0.046
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.029	0.029
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.029	0.029
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.029	0.029
HDAC6	HDAC6, JM21: Histone deacetylase 6	0.029	0.038
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.029	0.063
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.029	0.029
DOK1	DOK1: Docking protein 1	0.029	0.086
METTL1	METTL1, C12orf1: tRNA	0.029	0.038
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.029	0.038
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.029	0.046
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.029	0.029
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.029	0.029
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.029	0.038
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.029	0.046
CUL4B	N/A	0.029	0.046
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.029	0.046
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.029	0.139
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	0.029	0.029
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.029	0.029
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.029	0.038
CDK6	CDK6: Cell division protein kinase 6	0.029	0.038
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.029	0.029
RELA	RELA, NFKB3: Transcription factor p65	0.029	0.038
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.029	0.038
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.029	0.114
CXorf9	N/A	0.029	0.071
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.029	0.038
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.029	0.046
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.029	0.046
MTF1	MTF1: Metal regulatory transcription factor 1	0.029	0.029
ARMET	ARMET, ARP: Protein ARMET precursor	0.029	0.046
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.029	0.063
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.029	0.038
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.029	0.038
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.029	0.046
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.029	0.038
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.029	0.029
DYNC1LI1	DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1	0.029	0.029
BRPF1	BRPF1, BR140: Peregrin	0.029	0.038
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.029	0.029
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.029	0.029
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.028
MAPK15	N/A	0.028	0.028
ZNF265	N/A	0.028	0.028
C13orf8	N/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
PPEF1	N/A	0.028	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.028
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.028
CORO6	N/A	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
IRF7	N/A	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
DSP	DSP: Desmoplakin	0.028	0.028
WDR54	N/A	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.028	0.028
C20orf18	N/A	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.028	0.028
KIF1B	N/A	0.028	0.028
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.028	0.028
UHRF1		0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
PHLDB2	N/A	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.028
HES6	HES6: Transcription cofactor HES-6	0.028	0.028
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.028	0.028
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.028	0.028
SNRPB	N/A	0.028	0.028
RAB4A	N/A	0.028	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
NF2	NF2, SCH: Merlin	0.028	0.083
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.028	0.028
MAPKAPK5	N/A	0.028	0.028
BID	BID: BH3-interacting domain death agonist	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
HDAC8	N/A	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.028
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.028	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.028
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
CABLES1	N/A	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.028
RAD51AP1	N/A	0.027	0.027
MCM10	N/A	0.027	0.027
TMPO	N/A	0.027	0.027
C22orf18	N/A	0.027	0.027
IPO7	IPO7: Uncharacterized protein IPO7	0.027	0.036
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.027	0.036
SPTA1	SPTA1, SPTA: Spectrin alpha chain, erythrocyte	0.027	0.061
HD	HD, IT15: Huntingtin	0.027	0.027
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.027	0.036
PER2	PER2, KIAA0347: Period circadian protein homolog 2	0.026	0.026
RGS14	N/A	0.026	0.032
MECP2	MECP2: Methyl-CpG-binding protein 2	0.026	0.032
STAT2	STAT2: Signal transducer and activator of transcription 2	0.026	0.032
PRKAA1	N/A	0.026	0.032
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.026	0.032
ZFX	ZFX: Zinc finger X-chromosomal protein	0.026	0.032
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.026	0.032
ERF	ERF: ETS domain-containing transcription factor ERF	0.026	0.026
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.026	0.191
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.026	0.0425
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.026
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.026	0.032
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.026	0.026
NFATC1	N/A	0.026	0.0425
GTF3C1	N/A	0.026	0.032
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.026	0.026
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.026	0.026
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.026	0.0425
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.026	0.062
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.026	0.032
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.026	0.032
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.026	0.032
EEF2K	EEF2K: Elongation factor 2 kinase	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.025	0.075
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
CAMK2A	N/A	0.025	0.025
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.025
CAMKK1	N/A	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
ELMO1	N/A	0.025	0.075
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	0.025
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
NES	N/A	0.025	0.025
SON		0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.025
BCOR	N/A	0.025	0.025
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.025
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
GRK6	N/A	0.025	0.025
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
C20orf77	N/A	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.025
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.025	0.047
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.025
HDAC7A	N/A	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.025	0.075
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.025	0.025
CDC2	CDC2: Cell division control protein 2 homolog	0.025	0.025
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.025
NUP98	N/A	0.025	0.025
ATXN2L	N/A	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
HTATIP	N/A	0.025	0.025
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.025
KCTD1		0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
PRKCB1	N/A	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.025	0.025
BRD4	N/A	0.025	0.025
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
NIPBL	N/A	0.025	0.025
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.025
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.025
DIDO1	N/A	0.025	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.025
MAX	MAX: Protein max	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.025
RNF20		0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.025
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.025	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
SEC13L1	N/A	0.025	0.025
GIT2	N/A	0.025	0.025
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.025
LMNA	LMNA, LMN1: Lamin-A/C	0.025	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.025	0.025
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.025	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.025
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.025
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.025	0.025
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
TCEA1	N/A	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.025	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.025
SOX8	SOX8: Transcription factor SOX-8	0.025	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.025	0.025
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
FLJ23436	N/A	0.025	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.025
PTTG1	PTTG1, EAP1, PTTG, TUTR1: Securin	0.025	0.025
DBF4	DBF4, ASK: Protein DBF4 homolog	0.025	0.025
NOLC1	NOLC1, KIAA0035: Nucleolar phosphoprotein p130	0.025	0.025

2.15E-3

Total Score

63.10