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Evidence of Interaction Between EIF2S2 and EIF2B2

The interaction score between EIF2S2 and EIF2B2 is 341.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EIF2S2 and EIF2B2 = 0.53

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

6.27E-3
Orthology
OrganismEIF2S2 OrthologueEIF2B2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YPL237W 1 YLR291C 1
  • Immunoprecipitation
  • AffinityCaptureMS

Get References From PubMed

worm Q21230 1 Q9XWD5 1
fly P41375 1 O76863 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.593
Domains No domains were used in calculating likelihood of interaction N/A
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation No localisation data was used in calculating likelihood of interaction
Transitive Score

The common interactors between EIF2S2 and EIF2B2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EIF2S2 andEIF2B2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EIF2S2 has 864 interactors and EIF2B2 has 36 interactors of which there are 13 common interactors.

Common InteractorName of Common InteractorScore for EIF2S2-Interactor (?)Score for EIF2B2-Interactor (?)
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 431.00 1.79
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 122.00 1.32
EIF5 EIF5: Eukaryotic translation initiation factor 5 22.60 0.685
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 17.50 0.902
EIF2B1 EIF2B1, EIF2BA: Translation initiation factor eIF-2B subunit alpha 1.84 1.10
KIAA0174 N/A 1.49 1.10
EIF2B3 EIF2B3: Translation initiation factor eIF-2B subunit gamma 1.10 0.902
EIF1B EIF1B: Eukaryotic translation initiation factor 1b 0.685 0.902
FOXK2 N/A 0.593 0.593
EIF1 EIF1, SUI1: Eukaryotic translation initiation factor 1 0.430 0.181
FLJ14977 N/A 0.119 0.119
LOC647058 similar to suppressor of initiator codon mutations, related sequence 1 0.119 0.119
NULL Putative uncharacterized protein (Fragment) 0.119 0.119
0.572
Total Score 341.00