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Evidence of Interaction Between KIT and GRB2

The interaction score between KIT and GRB2 is 121.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismKIT OrthologueGRB2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00018335 0.132 IPI00013864 0.559
human IPI00021396 0.132 IPI00013864 0.559
worm O76698 0.132 P29355 1
worm Q21038 0.132 P29355 1
worm Q21041 0.132 P29355 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in KIT and GRB2:
Domains in KITDomains in GRB2
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.
IPR001452 SH3
IPR000108 Neutrophil cytosol factor 2
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in KIT and GRB2 are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR008266 Tyrosine protein kinase, active site IPR001452 SH3 164.706
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR001245 Tyrosine protein kinase IPR001452 SH3 100.857
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR003599 Immunoglobulin subtype IPR000980 SH2 motif 66.4833
IPR003598 Immunoglobulin C-2 type IPR000980 SH2 motif 64.7072
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR008266 Tyrosine protein kinase, active site IPR000108 Neutrophil cytosol factor 2 43.9279
IPR013151 Immunoglobulin. IPR000980 SH2 motif 36.9251
IPR001824 Receptor tyrosine kinase, class III IPR001452 SH3 32.2626
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR003598 Immunoglobulin C-2 type IPR001452 SH3 26.0449
IPR001245 Tyrosine protein kinase IPR000108 Neutrophil cytosol factor 2 22.4767
IPR003599 Immunoglobulin subtype IPR001452 SH3 22.2905
IPR011009 Protein kinase-like IPR001452 SH3 20.4416
IPR007110 Immunoglobulin-like IPR001452 SH3 20.3228
IPR013151 Immunoglobulin. IPR001452 SH3 14.5395
IPR001824 Receptor tyrosine kinase, class III IPR000108 Neutrophil cytosol factor 2 9.24001
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001452 SH3 8.64336
IPR000719 Protein kinase IPR000108 Neutrophil cytosol factor 2 4.72045
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000108 Neutrophil cytosol factor 2 3.30483
IPR011009 Protein kinase-like IPR000108 Neutrophil cytosol factor 2 2.89179
IPR007110 Immunoglobulin-like IPR000108 Neutrophil cytosol factor 2 2.23913
IPR003599 Immunoglobulin subtype IPR000108 Neutrophil cytosol factor 2 2.21022
IPR003598 Immunoglobulin C-2 type IPR000108 Neutrophil cytosol factor 2 1.88257
IPR013151 Immunoglobulin. IPR000108 Neutrophil cytosol factor 2 1.39708

The background colour of the table refers to:

  • Blue Domain is only present in KIT
  • Yellow Domain is only present in GRB2
  • Green Domain is present in both KIT and GRB2

 0.980
Post-translational Modifications

Protein: KIT

PTMResidueReference
Dephosphorylation 570 PubMed, HPRD
N-linked 130 PubMed, HPRD
Phosphorylation 545 PubMed, HPRD
Phosphorylation 547 PubMed, HPRD
Phosphorylation 553 PubMed, HPRD
Phosphorylation 568 PubMed, HPRD
Phosphorylation 570 PubMed, HPRD
Phosphorylation 703 PubMed, HPRD
Phosphorylation 721 PubMed, HPRD
Phosphorylation 730 PubMed, HPRD
Phosphorylation 741 PubMed, HPRD
Phosphorylation 746 PubMed, HPRD
Phosphorylation 747 PubMed, HPRD
Phosphorylation 821 PubMed, HPRD
Phosphorylation 900 PubMed, HPRD
Phosphorylation 936 PubMed, HPRD
Phosphorylation 959 PubMed, HPRD

Protein: GRB2

PTMResidueReference
Phosphorylation 160 PubMed, HPRD
Localisation

Protein: KIT

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD

Protein: GRB2

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between KIT and GRB2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between KIT andGRB2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , KIT has 1344 interactors and GRB2 has 1488 interactors of which there are 798 common interactors.

Common InteractorName of Common InteractorScore for KIT-Interactor (?)Score for GRB2-Interactor (?)
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 487.00 0.148
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 422.00 1.17
CRKL CRKL: Crk-like protein 388.00 0.148
NCK2 NCK2: Cytoplasmic protein NCK2 315.00 0.148
STAT5B STAT5B: Signal transducer and activator of transcription 5B 214.00 0.098
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 127.00 0.878
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 112.00 422.00
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 69.80 11.50
GRAP GRAP: GRB2-related adapter protein 61.50 2.04
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 46.80 0.878
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 46.80 0.878
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 43.20 1.17
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 35.00 0.148
JUP JUP, CTNNG, DP3: Junction plakoglobin 15.80 0.047
SHC2 N/A 12.40 1.29
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 2.08 0.075
SHC4 SHC-transforming protein 4 1.07 1.07
LOC392481 N/A 1.07 1.07
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.165
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 1.17
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 0.148
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.165
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.902 1.17
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.902 1.17
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.902 1.30
SYK SYK: Tyrosine-protein kinase SYK 0.902 1.17
STAT3 0.878 0.148
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.808 0.148
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.808 1.17
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 1.17
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.808 1.17
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.731 0.165
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 1.30
JAK1 0.731 1.17
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.731 0.165
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.731 0.165
RIN1 RIN1: Ras and Rab interactor 1 0.655 0.148
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 1.17
CSK CSK: Tyrosine-protein kinase CSK 0.655 1.17
VAV1 VAV1, VAV: Proto-oncogene vav 0.655 0.148
BMX N/A 0.654 1.30
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 1.17
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.165
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.644 1.30
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.644 0.165
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.644 0.165
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.644 1.30
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.051
GRB10 N/A 0.617 0.051
CRK CRK: Proto-oncogene C-crk 0.617 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.051
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 1.30
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.577 0.148
STAT6 STAT6: Signal transducer and activator of transcription 6 0.577 0.148
LYN LYN: Tyrosine-protein kinase Lyn 0.577 1.17
APS SH2B2, APS: SH2B adapter protein 2 0.577 0.148
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.577 1.17
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.577 1.17
HCK N/A 0.577 1.17
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.577 0.148
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.553 0.046
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.520 1.17
STAT2 STAT2: Signal transducer and activator of transcription 2 0.497 0.109
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.483 0.098
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.403 0.109
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.361 18.00
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.109
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.318 8.34
STAT4 STAT4: Signal transducer and activator of transcription 4 0.318 0.098
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.307 0.109
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.275 0.878
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
SOCS5 SOCS5, CIS6, CISH5, CISH6, KIAA0671: Suppressor of cytokine signaling 5 0.251 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.027
IPO7 IPO7: Uncharacterized protein IPO7 0.202 0.028
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.200 0.265
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.191 0.109
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.109
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.181 0.148
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.181 0.148
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.171 0.098
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.171 0.878
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.166 0.165
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FN1 N/A 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.098
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.098
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
KIR3DL1 N/A 0.165 0.109
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.878
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
FYN N/A 0.162 0.265
GRB14 GRB14: Growth factor receptor-bound protein 14 0.162 0.027
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.152 0.109
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.152 0.165
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.152 0.109
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.152 0.109
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.152 0.109
EPOR EPOR: Erythropoietin receptor precursor 0.152 0.109
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.152 0.109
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.152 0.109
PTPRZ1 N/A 0.152 0.098
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.152 0.109
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.148 0.148
ATRN N/A 0.148 0.044
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.098
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.148 0.044
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.878
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.878
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 0.098
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.098
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.098
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.098
BSG N/A 0.148 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.878
GRB7 GRB7: Growth factor receptor-bound protein 7 0.143 0.027
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.143 0.027
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.136 0.098
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.127 0.049
GAB2 N/A 0.126 0.165
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.123 0.109
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.123 0.878
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.109
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.123 0.109
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.123 0.980
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.109
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.123 0.109
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.123 0.109
KEL KEL: Kell blood group glycoprotein 0.123 0.049
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.123 0.109
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.123 0.109
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.109
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.123 0.109
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.109
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.123 0.109
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.123 0.980
SORL1 SORL1: Sortilin-related receptor precursor 0.123 0.098
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.123 0.109
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.123 0.109
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.123 0.109
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.109
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.113 0.148
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.113 0.148
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.113 6.39
STMN1 STMN1, LAP18, OP18: Stathmin 0.113 0.025
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.113 0.148
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.111 0.098
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.111 0.878
DCC DCC: Netrin receptor DCC precursor 0.111 0.098
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.111 0.878
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.111 0.878
INSR INSR: Insulin receptor precursor 0.111 0.878
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.111 0.878
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.111 0.098
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.111 0.098
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.098
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
NF2 NF2, SCH: Merlin 0.109 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.083
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.148
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
PPEF1 N/A 0.109 0.052
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.052
PSCD2 N/A 0.109 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.148
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.109 0.047
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
CNN2 CNN2: Calponin-2 0.109 0.148
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.052
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.109
F3 F3: Tissue factor precursor 0.109 0.109
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.109
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.109
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.980
EGF EGF: Pro-epidermal growth factor precursor 0.109 0.109
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, testis-specific isoform precursor 0.109 0.049
GHR GHR: Growth hormone receptor precursor 0.109 0.109
PVR PVR, PVS: Poliovirus receptor precursor 0.109 0.109
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.109 0.109
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.109 0.109
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.109
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.109
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.109 0.109
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.109 0.109
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.109
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.109 0.109
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.109 0.109
LILRB1 N/A 0.109 0.109
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.109 0.109
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.109 0.109
ITGB4 N/A 0.109 0.109
MME MME, EPN: Neprilysin 0.109 0.049
CRLF3 N/A 0.109 0.109
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.109
PRLR PRLR: Prolactin receptor precursor 0.109 0.109
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.100 0.052
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.100 0.075
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.100 0.025
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.100 0.165
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.100 0.0688
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.098 0.109
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.098 0.109
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.109
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.109
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.098 0.109
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.098 0.109
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.098 0.109
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.098 0.109
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.109
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.098 0.109
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.098 0.109
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.109
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.098 0.109
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.098 0.109
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.098 0.109
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
ELMO1 N/A 0.098 0.148
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.098 0.075
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.075
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.148
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.098 0.075
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.148
ARHGEF7 N/A 0.098 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
SNX3 N/A 0.098 0.075
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.047
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.148
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
BMP1 N/A 0.098 0.030
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.047
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.075
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.047
MEP1B MEP1B: Meprin A subunit beta precursor 0.097 0.044
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.097 0.878
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.098
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.097 0.044
NEO1 NEO1, NGN: Neogenin precursor 0.097 0.098
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.878
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.097 0.148
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.097 0.098
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.878
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.097 0.878
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.097 0.878
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.097 0.878
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.097 0.878
TNC TNC, HXB: Tenascin precursor 0.097 0.098
MEP1A MEP1A: Meprin A subunit alpha precursor 0.097 0.044
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.096 0.109
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.094 0.044
SOS1 SOS1: Son of sevenless homolog 1 0.094 18.00
CDK6 CDK6: Cell division protein kinase 6 0.091 0.148
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.091 0.028
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.090 0.148
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.090 0.047
RDX RDX: Radixin 0.090 0.148
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.090 0.148
CD2AP CD2AP: CD2-associated protein 0.090 0.148
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.090 0.148
THOP1 THOP1: Thimet oligopeptidase 0.090 0.075
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.090 0.062
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.090 0.148
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.148
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 27.40
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.090 0.148
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.090 0.047
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.090 0.148
DOK1 DOK1: Docking protein 1 0.090 0.148
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.090 0.148
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.090 0.148
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.090 0.148
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.088 0.098
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.088 0.878
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.086 0.148
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.109
EDA N/A 0.083 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.049
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.0818 0.025
XPO1 XPO1, CRM1: Exportin-1 0.0818 0.025
THOC1 THOC1, HPR1: THO complex subunit 1 0.0818 0.025
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.081 0.165
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.0688
ROCK1 ROCK1: Rho-associated protein kinase 1 0.081 0.165
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.081 0.165
GAB1 GAB1: GRB2-associated-binding protein 1 0.081 0.165
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.081 0.148
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.081 0.056
GRLF1 N/A 0.081 0.083
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.081 0.047
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 1.30
IRS1 IRS1: Insulin receptor substrate 1 0.081 0.165
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.081 0.165
SPTAN1 N/A 0.081 0.165
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.081 0.165
S100B S100B: Protein S100-B 0.081 0.052
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.165
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.081 0.148
SNCB SNCB: Beta-synuclein 0.081 0.052
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.081 0.052
CNN3 CNN3: Calponin-3 0.081 0.148
ATP2B1 N/A 0.077 0.049
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.077 0.049
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.075 0.047
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.075 0.148
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.075 0.025
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.075 0.028
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.044
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.098
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.044
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.073 0.148
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.073 0.148
DLG2 DLG2: Disks large homolog 2 0.073 0.062
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.073 0.062
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.073 0.148
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.073 0.047
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.073 0.148
PSD TYL: TYL protein 0.073 0.148
MSN MSN: Moesin 0.073 0.148
CHP CHP: Calcium-binding protein p22 0.073 0.047
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.073 0.148
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.073 0.148
MMP11 MMP11, STMY3: Stromelysin-3 precursor 0.073 0.030
SH3BP5 N/A 0.073 0.025
PLD2 PLD2: Phospholipase D2 0.073 0.148
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.073 0.148
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.073 0.148
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.073 7.88
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.073 0.075
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.073 0.075
FNBP1 N/A 0.073 4.22
VWF VWF, F8VWF: von Willebrand factor precursor 0.073 0.062
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.073 0.148
TLN1 TLN1: Uncharacterized protein TLN1 0.073 0.148
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.073 0.148
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.073 7.88
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.073 0.148
TST TST: Thiosulfate sulfurtransferase 0.073 0.075
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.073 0.148
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.073 0.148
LGALS3BP LGALS3BP, M2BP: Galectin-3-binding protein precursor 0.072 0.034
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.072 0.052
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.072 0.165
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.165
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.072 0.0688
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.165
PRL PRL: Prolactin precursor 0.072 0.034
MMP13 MMP13: Collagenase 3 precursor 0.072 0.034
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.072 0.165
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.072 0.0688
CSH2 GH1: Somatotropin precursor 0.072 0.034
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.072 0.0688
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.072 0.052
MMP9 MMP9, CLG4B: Matrix metalloproteinase-9 precursor 0.072 0.034
CSPG2 N/A 0.072 0.0688
CTTN CTTN, EMS1: Src substrate cortactin 0.072 4.22
VASP VASP: Vasodilator-stimulated phosphoprotein 0.072 0.165
S100A3 S100A3, S100E: Protein S100-A3 0.072 0.052
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.072 0.165
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.0688
S100A7 S100A7, PSOR1: Protein S100-A7 0.072 0.052
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.098
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.071 0.098
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.069 0.148
CETN1 CETN1, CEN1, CETN: Centrin-1 0.0688 0.036
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.067 0.148
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.067 0.025
HSP90AA1 Hsp89-alpha-delta-N 0.067 0.025
CDK4 CDK4: Cell division protein kinase 4 0.067 0.148
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.067 0.025
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.067 0.148
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.067 0.148
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.065 0.052
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.065 0.165
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.065 0.165
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.064 0.047
DAB1 DAB1: Disabled homolog 1 0.064 0.148
MMP8 CLG1, MMP8: Neutrophil collagenase precursor 0.064 0.030
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.064 0.148
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.064 0.062
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.483
MYL3 MYL3: Myosin light polypeptide 3 0.064 0.047
TTN N/A 0.064 0.148
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.148
LCP1 LCP1, PLS2: Plastin-2 0.064 0.047
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.064 7.88
MMP7 MMP7, MPSL1, PUMP1: Matrilysin precursor 0.064 0.030
SORBS3 SORBS3, SCAM1: Vinexin 0.064 0.148
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.062
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.064 0.047
PSCD4 PSCD4, CYT4: Cytohesin-4 0.064 0.148
CXorf9 N/A 0.064 0.148
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.064 0.047
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.064 0.148
VIL2 N/A 0.064 0.148
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.064 0.047
GMIP GMIP: GEM-interacting protein 0.064 0.075
MMP1 MMP1, CLG: Interstitial collagenase precursor 0.064 0.030
DAB2 DAB2, DOC2: Disabled homolog 2 0.064 0.148
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.064 0.062
RASA3 RASA3: Ras GTPase-activating protein 3 0.064 0.148
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.064 0.047
MMP2 MMP2, CLG4A: 72 kDa type IV collagenase precursor 0.064 0.030
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.064 0.047
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.047
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.064 0.062
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.064 0.148
TLN2 TLN2: Uncharacterized protein TLN2 0.064 0.148
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.109
RYR2 RYR2: Ryanodine receptor 2 0.063 0.034
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.063 0.109
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.062 0.109
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.062 0.049
MT3 MT3: Metallothionein-3 0.062 0.056
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.062 0.109
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.098
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.036
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.058 0.148
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.058 8.68
PLD1 PLD1: Phospholipase D1 0.058 0.148
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.058 0.148
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.057 0.098
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.057 0.098
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.057 0.098
FUBP1 N/A 0.057 0.083
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.057 0.148
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.056 0.098
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.056 0.044
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.098
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.055 0.109
HPN HPN, TMPRSS1: Serine protease hepsin 0.055 0.044
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.055 0.049
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.055 0.049
CD44 N/A 0.055 0.04
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.055 0.049
BZRAP1 BZRAP1, KIAA0612, RBP1: Peripheral-type benzodiazepine receptor-associated prote 0.053 0.027
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.046
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
C9orf88 N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
PTPRA N/A 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
IGHG1 N/A 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
RAPH1 N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
NCAM1 N/A 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
IGHM N/A 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
MARK2 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
HLA-A N/A 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
UBAP2L N/A 0.051 0.051
IGHD N/A 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
PLEK PLEK, P47: Pleckstrin 0.051 0.109
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.051 0.098
CENTA1 CENTA1: Centaurin-alpha 1 0.051 0.0688
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.051 0.109
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.109
ETS2 ETS2: Protein C-ets-2 0.0513 0.109
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.051 0.025
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.051 0.148
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.051 0.148
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.051 0.148
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.051 0.148
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.051 0.025
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.051 0.025
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.051 0.148
MDN1 MDN1, KIAA0301: Midasin 0.051 0.025
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.051 0.025
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.051 0.148
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.051 0.025
SYMPK SYMPK, SPK: Symplekin 0.051 0.025
CTPS CTPS: CTP synthase 1 0.051 0.025
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.051 0.044
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.049 0.109
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.109
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.049 0.109
CCR5 CCR5: CCR5 receptor (Fragment) 0.049 0.109
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.028
MAPK15 N/A 0.049 0.165
MAP2K5 N/A 0.049 0.165
TSC2 TSC2, TSC4: Tuberin 0.049 0.025
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.028
MYO18A 0.049 0.025
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.049 0.044
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.049 0.044
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.049 0.098
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.049 0.044
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.049 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.044
FLT4 VEGFR3 long form 0.046 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
LMO7 N/A 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.046 0.098
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.046 0.098
HD HD, IT15: Huntingtin 0.0453 0.083
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.0453 0.052
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.0453 0.165
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.0453 0.028
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.0453 0.165
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0453 0.165
COBL N/A 0.0453 0.165
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.0453 0.028
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.0453 0.165
WEE1 WEE1: Wee1-like protein kinase 0.0453 0.148
TP73 TP73, P73: Tumor protein p73 0.045 0.109
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.044 0.098
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.025
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.148
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.148
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
NIPBL N/A 0.044 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.148
SEC24B SEC24B: Protein transport protein Sec24B 0.041 0.047
WWC2 WW and C2 domain containing 2 0.041 0.025
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.041 0.148
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.041 0.148
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.041 0.148
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.041 0.062
MAGED2 N/A 0.041 0.025
CDK2 CDK2: Cell division protein kinase 2 0.041 0.148
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.041 0.075
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.041 0.148
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.041 0.148
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.041 0.025
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.041 0.025
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.041 0.025
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.041 0.148
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.041 0.075
CDK5 CDK5: Cell division protein kinase 5 0.041 0.148
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.041 0.148
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.041 0.148
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.041 0.148
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.041 0.148
RPS6KB1 N/A 0.041 0.148
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.041 0.148
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.041 0.062
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.041 0.025
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.041 0.025
ANPEP ANPEP, APN, CD13, PEPN: Aminopeptidase N 0.041 0.030
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.098
ENPEP ENPEP: Glutamyl aminopeptidase 0.041 0.030
RYR1 0.041 0.030
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.041 0.098
COTL1 COTL1, CLP: Coactosin-like protein 0.04 0.025
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.083
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.04
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.038 0.051
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.038 0.051
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.038 0.051
DBN1 DBN1, D0S117E: Drebrin 0.037 0.028
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.037 0.165
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.165
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.037 0.028
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.037 0.165
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.037 0.025
RAB11FIP5 RAB11FIP5, GAF1, KIAA0857, RIP11: Rab11 family-interacting protein 5 0.037 0.025
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.037 0.028
CFL2 CFL2: Cofilin-2 0.036 0.025
GSN GSN: Gelsolin precursor 0.036 0.047
SVIL SVIL: Supervillin 0.036 0.047
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.098
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.035 0.044
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.035 0.044
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.035 0.044
ANXA3 ANXA3, ANX3: Annexin A3 0.034 0.04
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.034 0.04
SDC1 SDC1, SDC: Syndecan-1 precursor 0.034 0.049
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.034 0.046
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.0338 0.051
GJA5 GJA5: Gap junction alpha-5 protein 0.0338 0.051
CNN1 CNN1: Calponin-1 0.0338 0.046
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.0338 0.051
SYTL4 Endocrine transmitter regulatory protein 0.034 0.049
MAL2 MAL2: Protein MAL2 0.034 0.034
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.033 0.075
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.033 0.047
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.033 0.075
GMFB GMFB: Glia maturation factor beta 0.033 0.025
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.033 0.148
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.033 0.148
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.033 0.148
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.033 0.025
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.033 0.148
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.033 0.148
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.033 0.148
STK10 STK10: Uncharacterized protein STK10 0.033 0.148
DYRK3 N/A 0.033 0.148
FLII FLII, FLIL: Protein flightless-1 homolog 0.033 0.047
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.033 0.148
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.033 0.025
KIAA0690 N/A 0.033 0.025
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.033 0.148
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.033 0.025
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.033 0.025
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.033 0.148
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.033 0.148
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.033 0.148
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.033 0.025
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.148
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.148
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.033 0.148
CFI CFI, IF: Complement factor I precursor 0.032 0.034
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.028
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.028
GAS2 GAS2: Growth arrest-specific protein 2 0.032 0.028
PRKAA1 N/A 0.032 0.165
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.032 0.148
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.165
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.032 0.025
FLNA FLNA, FLN, FLN1: Filamin-A 0.032 0.028
STK16 N/A 0.032 0.165
CDKL5 N/A 0.032 0.165
PLCB4 PLCB4: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.032 0.027
TOM1L1 TOM1L1, SRCASM: TOM1-like protein 1 0.031 0.049
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.031 0.04
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.0308 0.044
SDC4 SDC4: Syndecan-4 precursor 0.0308 0.044
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.0308 0.237
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.0308 0.217
TNN TNN: Tenascin-N precursor 0.030 0.046
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.046
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.046
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.098
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.098
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.044
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.098
KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 0.030 0.028
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.030 0.0688
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.030 0.050
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.029 0.165
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.029 0.148
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.029 0.148
ATM ATM: Serine-protein kinase ATM 0.029 0.148
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.148
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.029 0.148
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.029 0.148
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.029 0.148
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.148
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.029 0.025
WASPIP N/A 0.029 7.88
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.029 0.148
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.029 0.025
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.148
MYO3A MYO3A: Myosin IIIA 0.029 0.148
CDK7 CDK7, MO15: Cell division protein kinase 7 0.029 0.148
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.029 0.075
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.148
KCNJ12 KCNJ12, IRK2, KCNJN1: ATP-sensitive inward rectifier potassium channel 12 0.029 0.044
TSHR N/A 0.029 0.044
DLG1 N/A 0.029 0.025
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.028 0.044
PMP2 PMP2: Myelin P2 protein 0.027 0.075
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.027 0.075
HDLBP HDLBP, HBP, VGL: Vigilin 0.027 0.075
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.027 0.075
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.027 0.075
DSTN DSTN, ACTDP, DSN: Destrin 0.027 0.025
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
FGFR2 N/A 0.027 0.217
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.0263 0.0688
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.0263 0.0688
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.0263 0.0688
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.026 0.148
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.148
PARVA PARVA, MXRA2: Alpha-parvin 0.026 0.025
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.026 0.030
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.026 0.148
FES N/A 0.0258 0.0258
ADCY3 ADCY3, KIAA0511: Adenylate cyclase type 3 0.026 0.044
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.026 0.049
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.026 0.049
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.026 0.148
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.109
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.109
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.025 0.036
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.044
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.098
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.044
0.347
Total Score 121.00