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Evidence of Interaction Between CD3D and CD3G

The interaction score between CD3D and CD3G is 496.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between CD3D and CD3G = 0.96

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 0.082
Orthology N/A N/A
Domains Domains present in CD3D and CD3G:
Domains in CD3DDomains in CD3G
IPR003110 Phosphorylated immunoreceptor signaling ITAM
IPR003598 Immunoglobulin C-2 type
IPR007110 Immunoglobulin-like
IPR003110 Phosphorylated immunoreceptor signaling ITAM

The Chi square scores for co-occurrence of domains that are present in CD3D and CD3G are listed below.

Domain 1Domain 2Chi Square
IPR003110 Phosphorylated immunoreceptor signaling ITAM IPR003110 Phosphorylated immunoreceptor signaling ITAM 174.062
IPR003110 Phosphorylated immunoreceptor signaling ITAM IPR007110 Immunoglobulin-like 37.4282
IPR003110 Phosphorylated immunoreceptor signaling ITAM IPR003598 Immunoglobulin C-2 type 8.64408

The background colour of the table refers to:

  • Blue Domain is only present in CD3D
  • Yellow Domain is only present in CD3G
  • Green Domain is present in both CD3D and CD3G

 0.165
Post-translational Modifications

Protein: CD3D

PTMResidueReference
Phosphorylation 149 PubMed, HPRD
Phosphorylation 160 PubMed, HPRD
Phosphotyrosine 149 HPRD
Phosphotyrosine 160 HPRD

Protein: CD3G

PTMResidueReference
Glycosylation 52 PubMed, HPRD
Glycosylation 92 PubMed, HPRD
Phosphorylation 160 PubMed, HPRD
Phosphorylation 171 PubMed, HPRD
Phosphoserine 145 HPRD
Phosphoserine 148 HPRD
Localisation

Protein: CD3D

LocalisationReference
Plasma membrane HPRD

Protein: CD3G

LocalisationReference
Plasma membrane HPRD
Transitive Score

The common interactors between CD3D and CD3G that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CD3D andCD3G. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CD3D has 671 interactors and CD3G has 1138 interactors of which there are 666 common interactors.

Common InteractorName of Common InteractorScore for CD3D-Interactor (?)Score for CD3G-Interactor (?)
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 5.45 1.81
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 1.19 3.59
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.852 1.81
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.561 1.19
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.561 0.561
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.515 0.416
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.340 0.340
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.307 0.515
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.307 0.307
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.307 0.307
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.274 0.340
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.274 0.202
CD7 CD7: T-cell antigen CD7 precursor 0.251 0.307
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.251 0.251
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.251 0.251
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.210 0.260
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.202 0.274
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.202 0.202
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.202 0.202
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.202 0.202
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.191 0.251
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.191 0.251
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.191 0.251
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.191 0.191
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.191 0.251
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.191 0.251
GPA33 GPA33: Cell surface A33 antigen precursor 0.191 0.191
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.173 0.214
STAT4 STAT4: Signal transducer and activator of transcription 4 0.173 0.173
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.173 0.128
VAV1 VAV1, VAV: Proto-oncogene vav 0.166 0.166
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.166 0.166
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.166 0.166
FNBP1 N/A 0.166 0.166
NCK2 NCK2: Cytoplasmic protein NCK2 0.166 0.126
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.166 0.202
CXorf9 N/A 0.166 0.202
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.165
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.165
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.165
CNTN4 CNTN4: Contactin-4 precursor 0.165 0.165
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.165
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.165
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.165
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.165
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.165 0.165
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.165
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.165
CNTN1 CNTN1: Contactin-1 precursor 0.165 0.165
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.165
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.165
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.165
KIR3DL1 N/A 0.165 0.165
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.165
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.165
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.165
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.165
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.165
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.165 0.165
BSG N/A 0.165 0.165
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.165
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.152 0.152
IL7R N/A 0.144 0.087
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.128 0.128
JAK1 0.126 0.166
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.126 0.166
MSN MSN: Moesin 0.126 0.166
CSK CSK: Tyrosine-protein kinase CSK 0.126 0.126
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.126 0.126
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.126 0.126
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.126 0.126
CRKL CRKL: Crk-like protein 0.126 0.100
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.126
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.126 0.126
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.126 0.126
STAT6 STAT6: Signal transducer and activator of transcription 6 0.126 0.126
RPS6KB1 N/A 0.126 0.126
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.124 0.124
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.124 0.124
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.123 0.123
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.123 0.123
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.123 0.123
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.123 0.123
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.110 0.110
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.110 0.098
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.110 0.098
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.110 0.110
PVR PVR, PVS: Poliovirus receptor precursor 0.110 0.098
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.110 0.110
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.109
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.109
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.109
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.109
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.109
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.109
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.109
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.109
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.109
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.109
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.109
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 0.109
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.109
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.109
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.109 0.109
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 0.109
STAT3 0.109 0.109
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.109
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.109
NF2 NF2, SCH: Merlin 0.109 0.109
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.109
MAPK15 N/A 0.109 0.109
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 0.109
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.109
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.109
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.109
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.109
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 0.109
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 0.109
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.109
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.109 0.109
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.109 0.109
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.109 0.109
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.109
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.109 0.109
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.109 0.109
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.109 0.098
DCC DCC: Netrin receptor DCC precursor 0.109 0.109
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.109 0.109
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.109 0.109
NEO1 NEO1, NGN: Neogenin precursor 0.109 0.109
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.109 0.109
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.109 0.123
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.109 0.109
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.109 0.109
LILRB1 N/A 0.109 0.109
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 0.109
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.109 0.109
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.109 0.109
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.109 0.109
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.109 0.109
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.109 0.109
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.109 0.109
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.109 0.109
KIT KIT: Mast/stem cell growth factor receptor precursor 0.109 0.098
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.109 0.109
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.109
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.109 0.109
HPN HPN, TMPRSS1: Serine protease hepsin 0.109 0.109
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.109 0.109
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 0.109
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.109 0.109
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.108 0.231
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.105 0.0794
ATM ATM: Serine-protein kinase ATM 0.101 0.101
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 0.100
STK16 N/A 0.100 0.100
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.100 0.100
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.100 0.081
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.100 0.100
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.100 0.100
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.100 0.100
CD2AP CD2AP: CD2-associated protein 0.100 0.100
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.100 0.100
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.100 0.100
VIL2 N/A 0.100 0.100
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.098 0.110
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.098
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.098 0.098
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.098 0.098
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.098 0.098
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.098 0.098
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.098 0.098
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.098 0.109
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.098 0.098
INSR INSR: Insulin receptor precursor 0.098 0.098
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.098 0.098
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.098 0.098
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.098 0.109
MET MET: Hepatocyte growth factor receptor precursor 0.098 0.098
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.110
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.098
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.098 0.098
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.098 0.098
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.098 0.098
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.098 0.098
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.096 0.191
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.088 0.110
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 0.083
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.083 0.165
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.083
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.083 0.165
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.083 0.165
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.083 0.165
CD1B CD1B: T-cell surface glycoprotein CD1b precursor 0.083 0.137
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.081
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.081 0.081
TLN1 TLN1: Uncharacterized protein TLN1 0.081 0.081
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.081 0.081
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.081 0.081
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.081 0.081
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.081 0.081
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.081 0.100
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.081 0.100
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.081
HCK N/A 0.081 0.081
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.081 0.081
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.081 0.081
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.081 0.081
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.077 0.077
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.077 0.077
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.077 0.096
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.075 0.075
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.075 0.091
STK10 STK10: Uncharacterized protein STK10 0.075 0.091
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.075 0.075
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.0727 0.0727
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.0727 0.0727
DLG2 DLG2: Disks large homolog 2 0.0727 0.0727
TLN2 TLN2: Uncharacterized protein TLN2 0.0727 0.0727
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.0727 0.0727
CTTN CTTN, EMS1: Src substrate cortactin 0.0727 0.0727
RDX RDX: Radixin 0.0727 0.0727
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.0727 0.0727
SPTAN1 N/A 0.072 0.072
LGALS3BP LGALS3BP, M2BP: Galectin-3-binding protein precursor 0.072 0.072
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.072 0.072
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.072
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.072 0.081
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.072 0.072
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.072 0.072
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.072
BMX N/A 0.072 0.072
ALK ALK: ALK tyrosine kinase receptor precursor 0.072 0.072
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.072 0.072
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.081
PRL PRL: Prolactin precursor 0.072 0.072
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.072 0.072
CSH2 GH1: Somatotropin precursor 0.072 0.072
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.072 0.072
SYK SYK: Tyrosine-protein kinase SYK 0.072 0.081
SORBS3 SORBS3, SCAM1: Vinexin 0.072 0.065
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.072 0.072
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.072
CSPG2 N/A 0.072 0.072
RIN1 RIN1: Ras and Rab interactor 1 0.072 0.072
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.072
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.072
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.072 0.072
TTN N/A 0.072 0.072
LYN LYN: Tyrosine-protein kinase Lyn 0.072 0.081
APS SH2B2, APS: SH2B adapter protein 2 0.072 0.072
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.070 0.052
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.0688
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.0688
B2M B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro 0.067 0.067
SEMA4D SEMA4D, CD100, SEMAJ: Semaphorin-4D precursor 0.067 0.083
BTN3A2 BTN3A2, BT3.2, BTF3, BTF4: Butyrophilin subfamily 3 member A2 precursor 0.067 0.067
CD1E CD1E, RP11-101J8.5-005, hCG_1640053: CD1e molecule 0.067 0.083
CD96 CD96: T-cell surface protein tactile precursor 0.067 0.067
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.065 0.072
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.065 0.065
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.065 0.065
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.065
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.065 0.065
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.065 0.065
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.065 0.065
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.065 0.065
STAM2 STAM2: Signal transducing adapter molecule 2 0.065 0.065
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.065 0.065
CFI CFI, IF: Complement factor I precursor 0.065 0.065
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.065 0.065
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.065
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.065 0.065
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.065 0.065
STAT2 STAT2: Signal transducer and activator of transcription 2 0.063 0.063
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.062 0.062
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.061 0.075
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.059 0.059
PRKAA1 N/A 0.057 0.057
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.057 0.057
CDK2 CDK2: Cell division protein kinase 2 0.057 0.057
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.057 0.057
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.057 0.057
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.057
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.057 0.057
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.056 0.110
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.056 0.056
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.056 0.110
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.055 0.055
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.055 0.109
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.055 0.055
FYB FYB, SLAP130: FYN-binding protein 0.053 0.053
CCR5 CCR5: CCR5 receptor (Fragment) 0.052 0.052
CD69 CD69: Early activation antigen CD69 0.052 0.307
CRLF3 N/A 0.052 0.307
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.052 0.052
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.052 0.307
FLT4 VEGFR3 long form 0.051 0.051
IGHD N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
IGHM N/A 0.051 0.051
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
GRB10 N/A 0.051 0.051
HLA-A N/A 0.051 0.051
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.051
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
EPB41 EPB41, E41P: Protein 4.1 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
IGHG3 N/A 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NCAM1 N/A 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
EPN1 EPN1: Epsin-1 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.051
MARCO MARCO, SCARA2: Macrophage receptor MARCO 0.051 0.051
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.051
IL11RA IL11RA: Interleukin-11 receptor alpha chain precursor 0.050 0.050
LAG3 LAG3, FDC: Lymphocyte activation gene 3 protein precursor 0.050 0.050
SIGIRR SIGIRR, UNQ301/PRO342: Single Ig IL-1-related receptor 0.050 0.067
CD1C CD1C: T-cell surface glycoprotein CD1c precursor 0.050 0.067
BTN3A3 BTN3A3, BTF3: Butyrophilin subfamily 3 member A3 precursor 0.050 0.067
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.049 0.049
PTPRZ1 N/A 0.049 0.098
MAPKAPK5 N/A 0.049 0.049
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.049
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.049
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.049
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.049
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.049
MAP2K5 N/A 0.049 0.049
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.049
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.049 0.049
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.049
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.049 0.049
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.049
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.049
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.049
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.049 0.109
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.049
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.049
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.049
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.049
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.049
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.049
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.049
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.049
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.049
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.049 0.109
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.049
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.049
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.049
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.049
RAP80 UIMC1, RAP80, RXRIP110: Ubiquitin interaction motif-containing protein 1 0.047 0.047
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.0453 0.0453
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.0453 0.037
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.0453 0.0453
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.0453 0.057
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.0453 0.0453
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.0453 0.0453
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.0453 0.0453
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.0453 0.0453
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.0453 0.0453
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.0453 0.057
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.045
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0446 0.0446
EVL N/A 0.0446 0.0446
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.0425 0.127
SORL1 SORL1: Sortilin-related receptor precursor 0.0425 0.251
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.0407 0.051
EPHB6 EPHB6: Ephrin type-B receptor 6 precursor 0.041 0.0308
EEF2K EEF2K: Elongation factor 2 kinase 0.04 0.04
ARHGAP4 ARHGAP4, KIAA0131, RGC1, RHOGAP4: Rho GTPase-activating protein 4 0.039 0.039
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.039 0.039
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.038 0.038
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.037 0.037
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.037
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.037 0.037
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.037 0.037
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.037 0.037
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.037 0.037
LIMK2 LIMK2: LIM domain kinase 2 0.037 0.037
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.037 0.081
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.037 0.0453
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.037 0.037
WEE1 WEE1: Wee1-like protein kinase 0.037 0.037
CDK4 CDK4: Cell division protein kinase 4 0.037 0.037
ROCK1 ROCK1: Rho-associated protein kinase 1 0.037 0.037
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.037 0.037
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.0453
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.037 0.0453
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.037 0.037
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.037 0.037
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.037 0.037
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.037 0.0453
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.037 0.037
CASP8 N/A 0.036 0.036
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.036 0.027
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.036 0.124
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.0338 0.0338
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.034
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.034 0.0688
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.034
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.033 0.033
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.033
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.033 0.029
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.032 0.032
DAPK2 DAPK2: Death-associated protein kinase 2 0.032 0.032
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.032
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.032 0.032
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.032 0.032
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.032 0.032
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.032 0.032
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.032 0.032
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.032
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.032
CDK6 CDK6: Cell division protein kinase 6 0.032 0.032
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.032
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.032
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.032 0.032
CDK7 CDK7, MO15: Cell division protein kinase 7 0.032 0.032
CDK5 CDK5: Cell division protein kinase 5 0.032 0.032
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.032
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.032 0.032
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.032 0.032
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.032 0.032
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.032
CDKL5 N/A 0.032 0.032
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.032 0.100
ITGB7 ITGB7: Integrin beta-7 precursor 0.032 0.251
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.032 0.026
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.032 0.191
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.032 0.026
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.032 0.032
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.032 0.127
EDG1 EDG1: Sphingosine 1-phosphate receptor Edg-1 0.032 0.032
PRKX PRKX, PKX1: Serine/threonine-protein kinase PRKX 0.032 0.032
GRAP GRAP: GRB2-related adapter protein 0.032 0.032
ARHGEF7 ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB: Rho guanine nucleotide exchange 0.032 0.032
FYN N/A 0.032 0.039
PRMT2 PRMT2, HMT1, HRMT1L1: Protein arginine N-methyltransferase 2 0.032 0.039
MICA MICA: MHC class I chain-related protein A 0.0308 0.0308
LTK LTK, TYK1: Leukocyte tyrosine kinase receptor precursor 0.0308 0.0308
IL18RAP IL18RAP: Interleukin-18 receptor accessory protein precursor 0.0308 0.041
ICOS ICOS, AILIM: Inducible T-cell co-stimulator precursor 0.0308 0.0308
CD84 N/A 0.0308 0.0308
RYK RYK, JTK5A: Tyrosine-protein kinase RYK precursor 0.0308 0.0308
TAPBPL TAPBPL: Tapasin-related protein precursor 0.0308 0.0308
NCR3 NCR3, 1C7, LY117: Natural cytotoxicity triggering receptor 3 precursor 0.0308 0.041
LRRN3 LRRN3, Nbla10363, UNQ194/PRO220: Leucine-rich repeat neuronal protein 3 precurso 0.0308 0.0308
HLA-F HLA-F, HLA-5.4, HLAF: HLA class I histocompatibility antigen, alpha chain F prec 0.0308 0.041
HLA-E HLA-E, XXbac-BPG34K20.2-001: MHC class Ib antigen 0.0308 0.041
IL18R1 IL18R1, IL1RRP: Interleukin-18 receptor 1 precursor 0.0308 0.041
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.030 0.030
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.030 0.0453
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.029
MYO3A MYO3A: Myosin IIIA 0.029 0.029
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.029 0.029
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.029 0.029
DYRK3 N/A 0.029 0.029
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.029
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.029
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.029 0.029
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.029 0.029
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.029 0.029
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.029 0.029
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.029 0.032
CEACAM5 CEACAM5, CEA: Carcinoembryonic antigen-related cell adhesion molecule 5 precurso 0.029 0.029
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.028
PTPRA N/A 0.028 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.028 0.028
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.028 0.028
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.083
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.028 0.028
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.028 0.083
ATP1B1 N/A 0.028 0.028
DLK1 DLK1, DLK: Delta-like protein precursor 0.028 0.083
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.028 0.083
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.028 0.028
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.028 0.028
EDA N/A 0.028 0.083
C2orf7 PAP21, C2orf7, UNQ833/PRO1760: Protease-associated domain-containing protein of 0.028 0.028
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.028 0.028
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.028 0.028
FGFR2 N/A 0.028 0.028
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.028 0.028
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.083
GPRC5A GPRC5A, GPCR5A, RAI3, RAIG1: Retinoic acid-induced protein 3 0.028 0.028
SLC7A3 SLC7A3, ATRC3, CAT3: Cationic amino acid transporter 3 0.028 0.028
CSF3R N/A 0.028 0.028
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.028
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.028 0.083
JAG2 JAG2: Jagged-2 precursor 0.028 0.083
DRD2 DRD2: D(2) dopamine receptor 0.028 0.028
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.028 0.165
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.028 0.028
PCDH7 N/A 0.028 0.028
ATRN N/A 0.028 0.165
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.028
MUCDHL MUPCDH, MUCDHL, UNQ2781/PRO7168: Mucin and cadherin-like protein precursor 0.028 0.083
FN1 N/A 0.028 0.165
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.028 0.028
PCDHA2 PCDHA2: Protocadherin alpha 2 precursor 0.028 0.083
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.028
TREML1 TREML1, TLT1, UNQ1825/PRO3438: Trem-like transcript 1 protein precursor 0.028 0.028
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.028 0.028
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.028 0.083
SNAP25 N/A 0.028 0.028
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.028
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.028 0.083
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.028 0.028
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.028 0.165
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.028
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.028 0.083
AQP4 AQP4: Aquaporin-4 0.028 0.028
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.028 0.083
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.028 0.083
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.028 0.165
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.028 0.028
LAIR1 LAIR1, CD305: Leukocyte-associated immunoglobulin-like receptor 1 precursor 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
CDH6 CDH6: Cadherin-6 precursor 0.028 0.083
OPTC OPTC, OPT: Opticin precursor 0.028 0.083
ITGB1 N/A 0.028 0.028
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.028 0.083
TBXA2R TBXA2R: Thromboxane A2 receptor 0.028 0.028
TMPRSS9 N/A 0.028 0.028
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.028
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.028
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.028 0.028
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.028
PILRA PILRA: Paired immunoglobulin-like type 2 receptor alpha precursor 0.028 0.028
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 0.028 0.028
LAT N/A 0.027 0.027
HFE HFE, HLAH: Hereditary hemochromatosis protein precursor 0.027 0.027
LRIG3 LRIG3, LIG3, UNQ287/PRO326/PRO335: Leucine-rich repeats and immunoglobulin-like 0.027 0.027
BTLA BTLA: B- and T-lymphocyte attenuator precursor 0.027 0.027
PSG11 PSG11, PSG13, PSG14: Pregnancy-specific beta-1-glycoprotein 11 precursor 0.027 0.027
NFAM1 NFAM1, CNAIP: NFAT activation molecule 1 precursor 0.027 0.027
NRG2 NRG2, NTAK: Pro-neuregulin-2, membrane-bound isoform precursor 0.027 0.027
BTN2A2 N/A 0.027 0.027
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
CNTN5 CNTN5: Contactin-5 precursor 0.027 0.027
HLA-DQA1 HLA-DQA2, HLA-DXA: HLA class II histocompatibility antigen, DQ(6) alpha chain pr 0.027 0.027
HLA-DRB5 N/A 0.027 0.027
CD274 CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1: Programmed cell death 1 ligand 1 precursor 0.027 0.027
PTPRD PTPRD: PTPRD protein 0.027 0.027
FGFR2 N/A 0.027 0.027
SIGLEC11 N/A 0.027 0.027
SCN4B SCN4B: Sodium channel beta-4 subunit precursor 0.027 0.027
LILRB3 LILRB3, ILT5, LIR3: Leukocyte immunoglobulin-like receptor subfamily B member 3 0.027 0.027
IL1RAP N/A 0.027 0.027
CD8B CD8B, CD8B1: T-cell surface glycoprotein CD8 beta chain precursor 0.027 0.027
ROBO1 N/A 0.027 0.027
AGER AGER, RAGE: Advanced glycosylation end product-specific receptor precursor 0.027 0.027
FCAR FCAR, CD89: Immunoglobulin alpha Fc receptor precursor 0.027 0.027
CEACAM20 CEACAM20, UNQ9366/PRO34155: Carcinoembryonic antigen-related cell adhesion molec 0.027 0.027
SIGLEC6 N/A 0.027 0.027
SLAMF6 N/A 0.027 0.027
FCRL2 FCRL2, FCRH2, UNQ9236/PRO31998, IFGP4, IRTA4, SPAP1: Fc receptor-like protein 2 0.027 0.027
SIRPD N/A 0.027 0.027
TAS2R39 TAS2R39: Taste receptor type 2 member 39 0.027 0.027
FLJ44691 LRIT3: LRIT3 protein 0.027 0.027
ICAM4 ICAM4, LW: Intercellular adhesion molecule 4 precursor 0.027 0.027
HAPLN4 HAPLN4, BRAL2, KIAA1926: Hyaluronan and proteoglycan link protein 4 precursor 0.027 0.027
GUCY2F GUCY2F, GUC2F, RETGC2: Retinal guanylyl cyclase 2 precursor 0.027 0.027
HLA-DRB5 N/A 0.027 0.027
EMB EMB: Embigin precursor 0.027 0.027
LY9 LY9, CDABP0070: T-lymphocyte surface antigen Ly-9 precursor 0.027 0.027
AMIGO3 AMIGO3, ALI3, UNQ6084/PRO20089, KIAA1851: Amphoterin-induced protein 3 precursor 0.027 0.027
CD200R1 CD200R1, CD200R, CRTR2, MOX2R, OX2R: Cell surface glycoprotein OX2 receptor prec 0.027 0.027
DSCAM N/A 0.027 0.027
TIMD4 TIMD4, TIM4: T-cell immunoglobulin and mucin domain-containing protein 4 precurs 0.027 0.027
C20orf102 N/A 0.027 0.027
TMPRSS4 TMPRSS4, TMPRSS3, UNQ776/PRO1570: Transmembrane protease, serine 4 0.027 0.027
PTGFRN PTGFRN, CD9P1, FPRP, KIAA1436: Prostaglandin F2 receptor negative regulator prec 0.027 0.027
KIRREL2 KIRREL2, NEPH3, UNQ5827/PRO19646: Kin of IRRE-like protein 2 precursor 0.027 0.027
TMEM25 TMEM25, UNQ2531/PRO6030: Transmembrane protein 25 precursor 0.027 0.027
KIRREL3 KIRREL3, KIAA1867, UNQ5923/PRO4502/PRO19814, NEPH2: Kin of IRRE-like protein 3 p 0.027 0.027
FCGR2C FCGR2C, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.027 0.027
HAVCR2 HAVCR2, TIM3, TIMD3: Hepatitis A virus cellular receptor 2 precursor 0.027 0.027
SLAMF9 SLAMF9, CD2F10, UNQ1938/PRO4421: SLAM family member 9 precursor 0.027 0.027
VSIG2 VSIG2, CTH, UNQ2770/PRO7154, CTXL: V-set and immunoglobulin domain-containing pr 0.027 0.027
CRLF1 CRLF1, ZCYTOR5, UNQ288/PRO327: Cytokine receptor-like factor 1 precursor 0.027 0.027
LRFN5 LRFN5, C14orf146: Leucine-rich repeat and fibronectin type-III domain-containing 0.027 0.027
KIR2DL2 KIR2DL2, CD158B1, NKAT6: Killer cell immunoglobulin-like receptor 2DL2 precursor 0.027 0.027
LRRC4 LRRC4, BAG, NAG14, UNQ554/PRO1111: Leucine-rich repeat-containing protein 4 prec 0.027 0.027
LRRC21 LRRC21, PAL: Leucine-rich repeat-containing protein 21 precursor 0.027 0.027
PSG4 PSG4, CGM4, PSG9: Pregnancy-specific beta-1-glycoprotein 4 precursor 0.027 0.027
CNTN6 CNTN6: Contactin-6 precursor 0.027 0.027
SIGLEC7 SIGLEC7, AIRM1: Sialic acid-binding Ig-like lectin 7 precursor 0.027 0.027
TJP1 TJP1, ZO1: Tight junction protein ZO-1 0.027 0.027
PTPRT PTPRT, KIAA0283: Receptor-type tyrosine-protein phosphatase T precursor 0.027 0.027
KIR2DS5 KIR2DS5, CD158G, NKAT9: Killer cell immunoglobulin-like receptor 2DS5 precursor 0.027 0.027
MGC33530 N/A 0.027 0.027
BTNL9 BTNL9, UNQ1900/PRO4346: Butyrophilin-like protein 9 precursor 0.027 0.027
NEGR1 NEGR1, UNQ2433/PRO4993: Neuronal growth regulator 1 precursor 0.027 0.027
FGFRL1 FGFRL1, FGFR5, UNQ480/PRO943, FHFR: Fibroblast growth factor receptor-like 1 pre 0.027 0.027
ESAM ESAM, UNQ220/PRO246: Endothelial cell-selective adhesion molecule precursor 0.027 0.027
KIR2DL3 KIR2DL3, CD158B2, KIRCL23, NKAT2: Killer cell immunoglobulin-like receptor 2DL3 0.027 0.027
PSG6 PSG6, CGM3, PSGGB: Pregnancy-specific beta-1-glycoprotein 6 precursor 0.027 0.027
MADCAM1 MADCAM1: Mucosal addressin cell adhesion molecule 1 precursor 0.027 0.027
LRRN1 LRRN1, KIAA1497, Nbla10449, UNQ693/PRO1338: Leucine-rich repeat neuronal protein 0.027 0.027
PUNC PUNC: Putative neuronal cell adhesion molecule precursor 0.027 0.027
CD8A CD8A, MAL: T-cell surface glycoprotein CD8 alpha chain precursor 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.027 0.027
TMPRSS3 N/A 0.027 0.027
DCP1A DCP1A, SMIF: mRNA-decapping enzyme 1A 0.027 0.027
CCL5 CCL5, D17S136E, SCYA5: Small-inducible cytokine A5 precursor 0.027 0.091
TRRAP N/A 0.027 0.027
FUBP1 N/A 0.027 0.091
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.027 0.027
LPXN LPXN, LDLP: Leupaxin 0.027 0.027
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.027 0.027
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.027 0.027
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.0263 0.032
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0263 0.032
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.026 0.032
ATP2B4 ATP2B4, ATP2B2, MXRA1: Plasma membrane calcium-transporting ATPase 4 0.026 0.026
CD44 N/A 0.026 0.077
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.026 0.191
CD82 CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen 0.026 0.152
ITGAE ITGAE: Integrin alpha-E precursor 0.026 0.152
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.026 0.077
NCSTN NCSTN, KIAA0253, UNQ1874/PRO4317: Nicastrin precursor 0.026 0.026
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.026 0.077
GNA13 GNA13: Guanine nucleotide-binding protein alpha-13 subunit 0.026 0.026
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.025 0.051
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.025
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.025 0.051
0.228
Total Score 496.00