Home
Advanced Search
Help
Update History
Statistics
Downloads
The Barton Group
<<< Back to SMAD3

Evidence of Interaction Between SMAD3 and NUP214

The interaction score between SMAD3 and NUP214 is 11.5.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between SMAD3 and NUP214 = 0.25

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 2.88E-3
Orthology N/A N/A
Domains Domains present in SMAD3 and NUP214:
Domains in SMAD3Domains in NUP214
IPR008984 SMAD/FHA
IPR003619 Dwarfin protein, domain A
IPR001132 Dwarfin protein
IPR013019 MAD_MH1.
IPR001680 G-protein beta WD-40 repeat
IPR011046 WD40-like

The Chi square scores for co-occurrence of domains that are present in SMAD3 and NUP214 are listed below.

Domain 1Domain 2Chi Square
IPR001132 Dwarfin protein IPR001680 G-protein beta WD-40 repeat 2.15517
IPR013019 MAD_MH1. IPR001680 G-protein beta WD-40 repeat 2.15517
IPR003619 Dwarfin protein, domain A IPR001680 G-protein beta WD-40 repeat 2.10122
IPR008984 SMAD/FHA IPR001680 G-protein beta WD-40 repeat 0.012794

The background colour of the table refers to:

  • Blue Domain is only present in SMAD3
  • Yellow Domain is only present in NUP214
  • Green Domain is present in both SMAD3 and NUP214

 0.083
Post-translational Modifications

Protein: SMAD3

PTMResidueReference
Phosphorylation 8 PubMed, HPRD
Phosphorylation 179 PubMed, HPRD
Phosphorylation 204 PubMed, HPRD
Phosphorylation 208 PubMed, HPRD
Phosphorylation 213 PubMed, HPRD
Phosphorylation 422 PubMed, HPRD
Phosphorylation 423 PubMed, HPRD
Phosphorylation 425 PubMed, HPRD

Protein: NUP214

PTMResidueReference
Phosphorylation 467 PubMed, HPRD
Phosphorylation 474 PubMed, HPRD
Localisation

Protein: SMAD3

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: NUP214

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between SMAD3 and NUP214 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SMAD3 andNUP214. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SMAD3 has 962 interactors and NUP214 has 876 interactors of which there are 646 common interactors.

Common InteractorName of Common InteractorScore for SMAD3-Interactor (?)Score for NUP214-Interactor (?)
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 66.70 0.096
MTF1 MTF1: Metal regulatory transcription factor 1 54.60 0.052
CREBBP CREBBP, CBP: CREB-binding protein 41.40 0.0425
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 35.90 0.083
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 29.60 0.034
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 26.80 0.026
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 13.90 0.026
RUNX1 N/A 13.90 0.026
TCEB3 TCEB3, MSTP059: Transcription elongation factor B polypeptide 3 0.275 0.026
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.274 0.0446
ELF1 ELF1: ETS-related transcription factor Elf-1 0.210 0.0425
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.210 0.032
TGIF2 TGIF2: Homeobox protein TGIF2 0.210 0.026
WDR1 N/A 0.210 0.0425
GNB2L1 Lung cancer oncogene 7 0.210 0.080
SP100 N/A 0.210 0.096
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.0971
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.156
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.191 0.032
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.188 0.048
COPA COPA: Coatomer subunit alpha 0.188 0.032
SEC31L1 N/A 0.188 0.032
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.188 0.163
RAB4A N/A 0.165 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.165 0.028
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.165 0.028
ZFX ZFX: Zinc finger X-chromosomal protein 0.155 0.026
IRF3 IRF3: Interferon regulatory factor 3 0.155 0.060
NBN NBN, NBS, NBS1, P95: Nibrin 0.155 0.127
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.155 0.0425
GRLF1 N/A 0.152 0.026
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.152 0.062
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.148 0.027
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.148 0.028
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.148 0.165
COPB2 COPB2: Coatomer subunit beta' 0.139 0.032
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.139 0.032
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.139 0.048
CXorf9 N/A 0.139 0.052
JUNB JUNB: Transcription factor jun-B 0.139 0.087
YY1 YY1: Transcriptional repressor protein YY1 0.139 0.0425
SRF SRF: Serum response factor 0.139 0.032
CORO1C CORO1C, CRNN4: Coronin-1C 0.139 0.0425
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.139 0.0425
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.139 0.096
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.139 0.032
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.139 0.032
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.139 0.060
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.136 0.0425
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.127 0.032
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.127 0.032
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.127 0.062
GTF2F2 N/A 0.127 0.032
ERF ERF: ETS domain-containing transcription factor ERF 0.127 0.032
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.127 0.052
BACH1 BACH1: Transcription regulator protein BACH1 0.127 0.144
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.118 0.0425
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.114 0.025
PPP1R8 N/A 0.114 0.032
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.114 0.077
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.114 0.052
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.114 0.026
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.114 0.052
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.114 0.077
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.114 0.032
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.060
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.114 0.060
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.114 0.026
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.114 0.060
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.114 0.132
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.114 0.026
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.114 0.026
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.114 0.026
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.114 0.060
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.114 0.0425
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.114 0.052
JUND JUND: Transcription factor jun-D 0.114 0.052
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.114 0.026
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.114 0.0425
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.114 0.0425
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.111 0.027
VAV1 VAV1, VAV: Proto-oncogene vav 0.111 0.027
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.110 0.056
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0971 0.032
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.096 0.039
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.096 0.032
H1FX H1FX: Histone H1x 0.096 0.0425
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.048
SAT SAT1, SAT: Diamine acetyltransferase 1 0.096 0.070
MATR3 MATR3, KIAA0723: Matrin-3 0.096 0.062
MEF2A N/A 0.096 0.032
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.094 0.031
NCOA3 N/A 0.087 0.032
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.087 0.127
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.087 0.032
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.087 0.048
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.087 0.032
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.087 0.096
TP53 TP53, P53: Cellular tumor antigen p53 0.087 0.026
SP3 SP3: Transcription factor Sp3 0.086 0.052
VDR VDR, NR1I1: Vitamin D3 receptor 0.086 0.0425
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.086 0.0425
JUN JUN: Transcription factor AP-1 0.086 0.032
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.086 0.032
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.086 0.026
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.086 0.0425
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.086 0.032
BRPF1 BRPF1, BR140: Peregrin 0.086 0.052
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.086 0.070
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.086 0.026
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.086 0.096
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.086 0.144
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.028
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.083 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.083 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.083 0.028
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.083 0.028
MAPK15 N/A 0.083 0.028
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.083 0.028
SYTL4 Endocrine transmitter regulatory protein 0.083 0.083
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.083 0.028
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.083 0.028
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.083 0.028
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.083 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.028
WDR54 N/A 0.083 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.083 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.083 0.028
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.0818 0.027
TRIP12 TRIP12, KIAA0045: Probable E3 ubiquitin-protein ligase TRIP12 0.0782 0.0407
NFIB N/A 0.077 0.056
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.077 0.039
SH3BP3 0.077 0.032
ETS2 ETS2: Protein C-ets-2 0.077 0.026
ZNF267 ZNF267: Zinc finger protein 267 0.077 0.0425
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.077 0.060
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.075 0.036
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.075 0.028
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.075 0.028
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.075 0.052
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.075 0.028
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.075 0.083
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.075 0.028
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.075 0.028
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.075 0.028
CREB1 CREB1: cAMP response element-binding protein 0.075 0.028
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.075 0.028
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.028
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.075 0.028
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.075 0.028
SOX8 SOX8: Transcription factor SOX-8 0.075 0.083
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.028
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.075 0.028
DLX3 DLX3: Homeobox protein DLX-3 0.075 0.052
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.075 0.083
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.083
GEMIN5 GEMIN5: Gem-associated protein 5 0.075 0.028
FLNA FLNA, FLN, FLN1: Filamin-A 0.074 0.027
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.071 0.0425
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.071 0.049
SOS1 SOS1: Son of sevenless homolog 1 0.071 0.152
IFI16 N/A 0.070 0.0425
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.070 0.026
NFATC1 N/A 0.070 0.026
VIM VIM: Vimentin 0.070 0.0425
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.070 0.032
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.070 0.0425
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.069 0.096
MAFG MAFG: Transcription factor MafG 0.069 0.032
SATB1 SATB1: DNA-binding protein SATB1 0.069 0.039
SOX4 SOX4: Transcription factor SOX-4 0.069 0.062
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.069 0.077
SP1 SP1, TSFP1: Transcription factor Sp1 0.069 0.026
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.069 0.096
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.069 0.055
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.069 0.048
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.069 0.032
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.069 0.026
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.067 0.037
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.067 0.027
LCP1 LCP1, PLS2: Plastin-2 0.067 0.027
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.063 0.127
KIAA1012 KIAA1012: Protein TRS85 homolog 0.063 0.080
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.063 0.155
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.063 0.0425
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.063 0.026
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.155
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.063 0.032
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.062 0.062
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.062 0.055
MYB MYB: Myb proto-oncogene protein 0.062 0.039
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.060 0.032
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.060 0.026
RB1 RB1: Retinoblastoma-associated protein 0.060 0.080
PRKAR1A PRKAR1A, PKR1, PRKAR1, TSE1: cAMP-dependent protein kinase type I-alpha regulato 0.057 0.0513
PRKAR2A PRKAR2A, PKR2, PRKAR2: cAMP-dependent protein kinase type II-alpha regulatory su 0.057 0.031
MYBL2 MYBL2, BMYB: Myb-related protein B 0.056 0.034
CDC20 CDC20: Cell division cycle protein 20 homolog 0.056 0.026
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.056 0.062
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.056 0.080
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.056 0.062
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.056 0.096
XPO1 XPO1, CRM1: Exportin-1 0.054 0.0453
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.054 0.060
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.054 0.032
SYMPK SYMPK, SPK: Symplekin 0.054 0.026
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.054 0.026
KIAA0690 N/A 0.054 0.0425
C20orf18 N/A 0.052 0.028
UHRF1 0.052 0.028
DDX21 DDX21: Nucleolar RNA helicase 2 0.052 0.060
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.052 0.026
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.032
RGS14 N/A 0.052 0.0425
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.052 0.026
MARK2 N/A 0.052 0.052
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.052 0.032
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.032
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.052 0.026
PTMA N/A 0.052 0.026
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.048
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.052 0.096
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.052 0.032
ROCK1 ROCK1: Rho-associated protein kinase 1 0.052 0.052
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.052 0.052
ARFGAP1 N/A 0.052 0.032
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.052 0.026
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.052 0.032
KIAA0853 N/A 0.052 0.026
PLEK PLEK, P47: Pleckstrin 0.052 0.0425
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.049 0.055
AXIN1 0.049 0.049
NKX2-5 NKX2-5, CSX, NKX2.5, NKX2E: Homeobox protein Nkx-2.5 0.049 0.034
EGR1 EGR1, ZNF225: Early growth response protein 1 0.049 0.026
SOX11 SOX11: Transcription factor SOX-11 0.049 0.055
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.049 0.055
ZFYVE16 ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16 0.049 0.032
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.048 0.048
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.047 0.028
NIPBL N/A 0.047 0.028
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.047 0.028
RBL1 RBL1: Retinoblastoma-like protein 1 0.047 0.052
BRD4 N/A 0.047 0.028
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.046 0.080
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.046 0.032
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.046 0.251
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.052
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.046 0.0971
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.046 0.032
RELA RELA, NFKB3: Transcription factor p65 0.046 0.032
RPS6KB1 N/A 0.046 0.026
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.046 0.026
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.046 0.0425
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.046 0.0971
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.046 0.096
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.046 0.032
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.046 0.060
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.046 0.026
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.046 0.096
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.046 0.026
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.046 0.032
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.046 0.032
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.046 0.026
STK10 STK10: Uncharacterized protein STK10 0.046 0.052
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.046 0.191
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.046 0.032
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.046 0.0425
FNBP1 N/A 0.046 0.032
WBSCR20A N/A 0.046 0.032
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.046 0.096
SAPS3 N/A 0.046 0.0425
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.046 0.0425
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.046 0.416
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.046 0.416
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.046 0.096
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.046 0.060
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.046 0.052
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 0.046 0.032
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.046 0.0425
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.046 0.032
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.046 0.132
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.046 0.096
CUL4B N/A 0.046 0.026
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.046 0.096
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.046 0.096
DOK1 DOK1: Docking protein 1 0.046 0.087
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.046 0.0425
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.046 0.0971
MYH9 MYH9: Myosin-9 0.046 0.0425
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.046 0.096
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.046 0.032
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.046 0.0425
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.046 0.0425
FBXL11 FBXL11, FBL7, JHDM1A, KIAA1004: JmjC domain-containing histone demethylation pro 0.044 0.041
EN2 EN2: Homeobox protein engrailed-2 0.044 0.039
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.043 0.026
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.0425 0.032
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.070
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.0425 0.070
ABCF1 N/A 0.0425 0.032
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.0425 0.026
TCOF1 N/A 0.0425 0.026
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.0425 0.191
STK16 N/A 0.0425 0.032
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.0425 0.062
SREBF2 N/A 0.0425 0.026
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.0425 0.032
SET SET: Protein SET 0.0425 0.026
RBM14 RBM14, SIP: RNA-binding protein 14 0.0425 0.127
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.0425 0.060
RBM6 RBM6, DEF3: RNA-binding protein 6 0.0425 0.077
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.0425 0.026
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.038 0.077
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.038 0.0425
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.038 0.0425
POLA2 POLA2: DNA polymerase subunit alpha B 0.038 0.026
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.038 0.096
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.038 0.060
NOL1 N/A 0.038 0.026
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.038 0.032
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.038 0.0425
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.038 0.096
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.038 0.096
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.038 0.0971
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.038 0.060
DIAPH1 Diaphanous 1 0.038 0.070
GSK3B N/A 0.038 0.052
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.026
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.038 0.060
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.038 0.096
PHF10 N/A 0.038 0.032
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.062
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.038 0.026
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.038 0.032
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.038 0.032
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.038 0.070
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.038 0.062
COPE COPE: Coatomer subunit epsilon 0.038 0.155
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.038 0.251
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.038 0.048
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.038 0.032
SSB SSB: Lupus La protein 0.038 0.077
RBM7 0.038 0.096
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.032
WDR44 WDR44: WD repeat-containing protein 44 0.038 0.032
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.038 0.0425
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.038 0.070
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.038 0.032
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.038 0.032
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.038 0.026
TIAL1 TIAL1: Nucleolysin TIAR 0.038 0.096
KLHDC4 N/A 0.038 0.026
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.038 0.026
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.038 0.026
CBX3 CBX3: Chromobox protein homolog 3 0.038 0.032
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.038 0.039
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.038 0.096
EP300 N/A 0.038 0.052
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.038 0.052
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.038 0.087
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.038 0.070
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.038 0.080
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.038 0.152
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.038 0.032
ARMET ARMET, ARP: Protein ARMET precursor 0.038 0.026
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.038 0.191
MTA1 MTA1: Metastasis-associated protein MTA1 0.038 0.077
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.038 0.048
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.038 0.0425
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.038 0.032
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.038 0.077
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.038 0.155
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.038 0.0425
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.038 0.032
AIP AIP, XAP2: AH receptor-interacting protein 0.038 0.060
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.038 0.032
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.038 0.155
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.038 0.0425
HDAC3 HDAC3: Histone deacetylase 3 0.038 0.096
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.038 0.070
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.038 0.026
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.038 0.096
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.038 0.096
CDK7 CDK7, MO15: Cell division protein kinase 7 0.038 0.032
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.038 0.077
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.038 0.026
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.038 0.077
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.038 0.0425
CUL5 CUL5, VACM1: Cullin-5 0.038 0.152
IFI35 N/A 0.036 0.027
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.035 0.026
PRKAA1 N/A 0.032 0.032
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.032 0.096
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.032 0.032
SMARCC2 N/A 0.032 0.026
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.032 0.096
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.032 0.032
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.032 0.026
DNMT1 DNMT1, AIM, DNMT: DNA 0.032 0.077
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.032 0.032
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.032 0.070
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.032 0.077
XRCC4 N/A 0.032 0.032
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.032 0.127
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.032 0.087
TRRAP N/A 0.032 0.026
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.026
TOP2B N/A 0.032 0.026
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.032 0.062
COIL COIL, CLN80: Coilin 0.032 0.052
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.032 0.032
CHUK N/A 0.032 0.032
XRCC1 XRCC1: DNA-repair protein XRCC1 0.032 0.096
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.026
ID2 ID2: DNA-binding protein inhibitor ID-2 0.032 0.032
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.032 0.027
STAT6 STAT6: Signal transducer and activator of transcription 6 0.032 0.036
FLII FLII, FLIL: Protein flightless-1 homolog 0.032 0.036
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.032 0.057
ACTG1 ACTB: Actin, cytoplasmic 1 0.032 0.027
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.032 0.036
CIC CIC, KIAA0306: Protein capicua homolog 0.031 0.0513
KCNH2 KCNH2, ERG, ERG1, HERG, HERG1: Potassium voltage-gated channel subfamily H membe 0.030 0.034
SAFB2 SAFB2, KIAA0138: Scaffold attachment factor B2 0.030 0.033
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.029 0.032
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.029 0.096
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.062
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.029 0.039
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.029 0.048
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.029 0.032
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.029 0.026
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.0425
NPM1 NPM1, NPM: Nucleophosmin 0.029 0.026
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.029 0.032
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.029 0.052
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.029 0.0425
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.029 0.077
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.029 0.096
HDAC2 HDAC2: Histone deacetylase 2 0.029 0.077
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.029 0.048
MDN1 MDN1, KIAA0301: Midasin 0.029 0.039
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.029 0.026
AHR AHR: Aryl hydrocarbon receptor precursor 0.029 0.052
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.029 0.026
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.029 0.032
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.029 0.152
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.029 0.032
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.029 0.251
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.029 0.062
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.029 0.026
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.029 0.191
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.060
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.029 0.070
FZR1 N/A 0.029 0.032
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.029 0.026
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.029 0.0425
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.029 0.052
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.029 0.034
NUP153 N/A 0.029 0.026
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.029 0.032
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.029 0.070
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.029 0.032
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.029 0.0425
KCTD12 KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12 0.029 0.070
KIF1B N/A 0.028 0.028
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
NES N/A 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
CORO6 N/A 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.052
HES6 HES6: Transcription cofactor HES-6 0.028 0.083
DSP DSP: Desmoplakin 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
HDAC8 N/A 0.028 0.083
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.083
BID BID: BH3-interacting domain death agonist 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ZNF265 N/A 0.028 0.028
C13orf8 N/A 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.083
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.083
IRF7 N/A 0.028 0.028
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.083
CABLES1 N/A 0.028 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.028 0.028
PPEF1 N/A 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.028 0.028
DUSP15 N/A 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.083
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
PHLDB2 N/A 0.028 0.028
SNRPB N/A 0.028 0.028
NTE N/A 0.028 0.0513
CUL2 CUL2: Cullin-2 0.027 0.051
MVP MVP, LRP: Major vault protein 0.027 0.027
LIMS1 N/A 0.027 0.036
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.027 0.036
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.027 0.027
DAPP1 N/A 0.027 0.027
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.026 0.032
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.026 0.032
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.026 0.077
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.026 0.032
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.032
GAB2 N/A 0.026 0.052
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.123
GTF3C1 N/A 0.026 0.026
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.026 0.0425
UBAP2 N/A 0.026 0.026
KCTD1 0.025 0.028
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.028
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.028
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.028
CCNT2 CCNT2: Cyclin-T2 0.025 0.028
TFAP4 TFAP4: Transcription factor AP-4 0.025 0.028
MAX MAX: Protein max 0.025 0.028
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.025 0.028
TCEA1 N/A 0.025 0.028
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.028
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.028
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.028
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.028
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.028
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.028
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.052
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.028
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.028
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.028
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.025 0.028
HDAC7A N/A 0.025 0.083
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.028
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.028
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.028
FLJ23436 N/A 0.025 0.028
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.083
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.025 0.028
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.028
MAP2K3 N/A 0.025 0.028
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.028
BCOR N/A 0.025 0.028
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.028
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.028
CDC2 CDC2: Cell division control protein 2 homolog 0.025 0.028
LMNA LMNA, LMN1: Lamin-A/C 0.025 0.028
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.025 0.083
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.028
RNF20 0.025 0.028
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.028
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.028
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.083
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.052
SEC13L1 N/A 0.025 0.028
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.028
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.028
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.083
ATXN2L N/A 0.025 0.028
ELMO1 N/A 0.025 0.028
DIDO1 N/A 0.025 0.028
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.028
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.028
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.083
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.028
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.083
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.028
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.025 0.028
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.025 0.052
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.025 0.028
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.025 0.028
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.028
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.028
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.028
CAMKK1 N/A 0.025 0.028
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.028
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.025 0.083
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.028
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.028
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.028
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.028
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.083
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.028
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.028
MAPK8IP3 N/A 0.025 0.028
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.083
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.028
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.028
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.028
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.028
GRK6 N/A 0.025 0.028
HTATIP N/A 0.025 0.028
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.028
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.083
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.028
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.025 0.028
PRKCB1 N/A 0.025 0.028
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.083
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.083
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.028
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.025 0.028
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.028
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.028
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.028
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.028
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.028
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.028
SON 0.025 0.028
GIT2 N/A 0.025 0.028
C20orf77 N/A 0.025 0.028
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.028
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.028
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.025 0.083
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.052
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.025 0.028
CAMK2A N/A 0.025 0.028
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.028
NUP98 N/A 0.025 0.028
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.028
ADK ADK: Adenosine kinase 0.025 0.028
0.299
Total Score 11.5