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Evidence of Interaction Between INSR and CSK

The interaction score between INSR and CSK is 47.30.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between INSR and CSK = -0.15

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

1.48E-3
Orthology
OrganismINSR OrthologueCSK OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00027232 0.438 IPI00552347 0.145
worm Q968Y9 0.438 Q9BL77 1
fly P09208 0.377 Q9VGK8 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3
Domains Domains present in INSR and CSK:
Domains in INSRDomains in CSK
IPR000494 Epidermal growth-factor receptor (EGFR), L domain
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR006211 Furin-like cysteine rich region
IPR006212 Furin-like repeat
IPR008266 Tyrosine protein kinase, active site
IPR003961 Fibronectin, type III
IPR002011 Receptor tyrosine kinase, class II
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR001452 SH3
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in INSR and CSK are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR003961 Fibronectin, type III IPR000980 SH2 motif 184.508
IPR008266 Tyrosine protein kinase, active site IPR001452 SH3 164.706
IPR001245 Tyrosine protein kinase IPR001452 SH3 100.857
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR000494 Epidermal growth-factor receptor (EGFR), L domain IPR000980 SH2 motif 46.2087
IPR006211 Furin-like cysteine rich region IPR000980 SH2 motif 46.2087
IPR006212 Furin-like repeat IPR000980 SH2 motif 43.075
IPR000719 Protein kinase IPR000719 Protein kinase 30.6895
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR002011 Receptor tyrosine kinase, class II IPR000980 SH2 motif 24.6768
IPR003961 Fibronectin, type III IPR008266 Tyrosine protein kinase, active site 22.1621
IPR003961 Fibronectin, type III IPR001452 SH3 15.104
IPR008266 Tyrosine protein kinase, active site IPR008266 Tyrosine protein kinase, active site 9.50479
IPR000719 Protein kinase IPR008266 Tyrosine protein kinase, active site 6.98997
IPR003961 Fibronectin, type III IPR001245 Tyrosine protein kinase 6.5864
IPR000494 Epidermal growth-factor receptor (EGFR), L domain IPR001452 SH3 4.57189
IPR006211 Furin-like cysteine rich region IPR001452 SH3 4.57189
IPR006212 Furin-like repeat IPR001452 SH3 3.92763
IPR000719 Protein kinase IPR011009 Protein kinase-like 2.94434
IPR000719 Protein kinase IPR001245 Tyrosine protein kinase 2.31134
IPR006212 Furin-like repeat IPR000719 Protein kinase 1.94477
IPR002011 Receptor tyrosine kinase, class II IPR001452 SH3 1.57489
IPR000494 Epidermal growth-factor receptor (EGFR), L domain IPR000719 Protein kinase 1.5062
IPR006211 Furin-like cysteine rich region IPR000719 Protein kinase 1.5062
IPR002011 Receptor tyrosine kinase, class II IPR000719 Protein kinase 1.16654
IPR001245 Tyrosine protein kinase IPR008266 Tyrosine protein kinase, active site 0.959759
IPR003961 Fibronectin, type III IPR000719 Protein kinase 0.712801
IPR003961 Fibronectin, type III IPR011009 Protein kinase-like 0.616354
IPR002011 Receptor tyrosine kinase, class II IPR001245 Tyrosine protein kinase 0.432179
IPR002011 Receptor tyrosine kinase, class II IPR011009 Protein kinase-like 0.315004
IPR000494 Epidermal growth-factor receptor (EGFR), L domain IPR008266 Tyrosine protein kinase, active site 0.214051
IPR006211 Furin-like cysteine rich region IPR008266 Tyrosine protein kinase, active site 0.214051
IPR006212 Furin-like repeat IPR011009 Protein kinase-like 0.180255
IPR001245 Tyrosine protein kinase IPR011009 Protein kinase-like 0.178275
IPR006212 Furin-like repeat IPR008266 Tyrosine protein kinase, active site 0.113534
IPR000494 Epidermal growth-factor receptor (EGFR), L domain IPR011009 Protein kinase-like 0.0778402
IPR006211 Furin-like cysteine rich region IPR011009 Protein kinase-like 0.0778402
IPR001245 Tyrosine protein kinase IPR001245 Tyrosine protein kinase 0.0451828
IPR002011 Receptor tyrosine kinase, class II IPR008266 Tyrosine protein kinase, active site 0.0235657
IPR006212 Furin-like repeat IPR001245 Tyrosine protein kinase 0.00835708
IPR008266 Tyrosine protein kinase, active site IPR011009 Protein kinase-like 0.00724826
IPR000494 Epidermal growth-factor receptor (EGFR), L domain IPR001245 Tyrosine protein kinase 0.000919029
IPR006211 Furin-like cysteine rich region IPR001245 Tyrosine protein kinase 0.000919029

The background colour of the table refers to:

  • Blue Domain is only present in INSR
  • Yellow Domain is only present in CSK
  • Green Domain is present in both INSR and CSK

0.980
Post-translational Modifications

Protein: INSR

PTMResidueReference
Dephosphorylation 999 PubMed, HPRD
Dephosphorylation 1185 PubMed, HPRD
Dephosphorylation 1189 PubMed, HPRD
Dephosphorylation 1190 PubMed, HPRD
Glycosylation 43 PubMed, HPRD
Glycosylation 52 PubMed, HPRD
Glycosylation 105 PubMed, HPRD
Glycosylation 138 PubMed, HPRD
Glycosylation 424 PubMed, HPRD
Glycosylation 445 PubMed, HPRD
Glycosylation 769 PubMed, HPRD
Glycosylation 782 PubMed, HPRD
Glycosylation 920 PubMed, HPRD
Glycosylation 933 PubMed, HPRD
N-linked 541 PubMed, HPRD
Phosphorylation 992 PubMed, HPRD
Phosphorylation 999 PubMed, HPRD
Phosphorylation 1062 PubMed, HPRD
Phosphorylation 1064 PubMed, HPRD
Phosphorylation 1185 PubMed, HPRD
Phosphorylation 1189 PubMed, HPRD
Phosphorylation 1190 PubMed, HPRD
Phosphorylation 1314 PubMed, HPRD
Phosphorylation 1332 PubMed, HPRD
Phosphorylation 1333 PubMed, HPRD
Phosphorylation 1348 PubMed, HPRD
Phosphorylation 1354 PubMed, HPRD
Phosphorylation 1355 PubMed, HPRD
Phosphorylation 1361 PubMed, HPRD
Phosphorylation 1362 PubMed, HPRD
Phosphorylation 1375 PubMed, HPRD
Phosphotyrosine 992 PubMed, HPRD
Phosphotyrosine 999 PubMed, HPRD
Phosphotyrosine 1011 PubMed, HPRD
Phosphotyrosine 1185 PubMed, HPRD
Phosphotyrosine 1189 PubMed, HPRD
Phosphotyrosine 1190 PubMed, HPRD
Phosphotyrosine 1355 PubMed, HPRD
Phosphotyrosine 1361 PubMed, HPRD

Protein: CSK

PTMResidueReference
Phosphorylation 184 PubMed, HPRD
Phosphorylation 304 PubMed, HPRD
Phosphorylation 364 PubMed, HPRD
Phosphotyrosine 184 HPRD
Phosphotyrosine 304 PubMed, HPRD
Localisation

Protein: INSR

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD

Protein: CSK

LocalisationReference
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between INSR and CSK that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between INSR andCSK. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , INSR has 1177 interactors and CSK has 1875 interactors of which there are 814 common interactors.

Common InteractorName of Common InteractorScore for INSR-Interactor (?)Score for CSK-Interactor (?)
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 388.00 0.781
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 277.00 2.17
JAK2 JAK2: Tyrosine-protein kinase JAK2 277.00 2.94
CRKL CRKL: Crk-like protein 277.00 2.94
STAT5B STAT5B: Signal transducer and activator of transcription 5B 173.00 2.20
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 71.20 0.098
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 61.50 0.141
GRAP GRAP: GRB2-related adapter protein 61.50 0.440
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 56.70 0.066
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 46.90 0.148
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 15.80 0.099
YWHAB YWHAB: 14-3-3 protein beta/alpha 12.50 0.078
SHC2 N/A 12.40 0.0258
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 6.81 0.074
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 1.30
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 1.30
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 1.30
BMX N/A 0.902 0.775
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.902 0.964
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.878 1.17
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.878 1.17
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.878 1.17
STAT3 0.878 1.17
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.878 1.17
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 1.98
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.731 1.20
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.655 0.770
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.644 1.98
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.644 4.07
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.644 0.775
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.644 4.07
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.644 1.20
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.644 0.859
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.617
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.617
GRB10 N/A 0.617 0.617
CRK CRK: Proto-oncogene C-crk 0.617 0.617
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.586 6.03
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.581 1.50
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.581 3.28
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.581 2.42
RIN1 RIN1: Ras and Rab interactor 1 0.577 0.874
STAT6 STAT6: Signal transducer and activator of transcription 6 0.577 12.80
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.577 1.07
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.577 1.78
SYK SYK: Tyrosine-protein kinase SYK 0.577 6.03
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.577 6.03
APS SH2B2, APS: SH2B adapter protein 2 0.577 2.94
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.577 0.874
HCK N/A 0.577 2.17
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.577 12.80
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.577 0.694
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.577 3.64
LYN LYN: Tyrosine-protein kinase Lyn 0.577 6.03
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.553 0.553
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.553
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.520 2.17
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.520 2.17
VAV1 VAV1, VAV: Proto-oncogene vav 0.520 12.80
JAK1 0.520 3.64
NCK2 NCK2: Cytoplasmic protein NCK2 0.520 2.94
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.483 0.878
STAT2 STAT2: Signal transducer and activator of transcription 2 0.403 1.81
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.644
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.320 3.05
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.318 0.655
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.318 2.73
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.307 0.072
STAT4 STAT4: Signal transducer and activator of transcription 4 0.286 1.33
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.265
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.265
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.265
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.265
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.202 0.045
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.202 0.045
GRB7 GRB7: Growth factor receptor-bound protein 7 0.200 0.157
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.191 0.519
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.191 0.519
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.058
DAB2 DAB2, DOC2: Disabled homolog 2 0.181 0.097
VAV3 VAV3: Protein vav-3 0.179 0.440
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.171 0.520
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.171 1.33
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.171 0.465
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.165 0.049
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.109
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
FN1 N/A 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
KIR3DL1 N/A 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
GRB14 GRB14: Growth factor receptor-bound protein 14 0.162 0.176
PRLR PRLR: Prolactin receptor precursor 0.152 0.065
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.152 0.126
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.152 0.058
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.152 0.0727
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.098
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.098
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.148 0.878
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.878
ATRN N/A 0.148 0.044
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.098
BSG N/A 0.148 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.878
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.878
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.098
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.098
SHB SHB: SH2 domain-containing adapter protein B 0.145 0.158
SOCS2 SOCS2, CIS2, SSI2, STATI2: Suppressor of cytokine signaling 2 0.145 0.177
SOCS5 SOCS5, CIS6, CISH5, CISH6, KIAA0671: Suppressor of cytokine signaling 5 0.143 0.174
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.136 0.058
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.136 0.586
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.136 0.577
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.136 0.058
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.129 0.491
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.129 0.491
FYN N/A 0.129 0.824
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.128 0.440
CHN2 CHN2, ARHGAP3, BCH: Beta-chimaerin 0.128 0.141
RIN3 N/A 0.128 0.739
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.127 0.029
CNN3 CNN3: Calponin-3 0.126 0.110
CGA CGA: Glycoprotein hormones alpha chain precursor 0.126 0.045
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.126 0.046
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.123 0.072
GHR GHR: Growth hormone receptor precursor 0.123 0.126
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.123 0.100
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.123 0.166
MET MET: Hepatocyte growth factor receptor precursor 0.123 0.654
ITGB4 N/A 0.123 0.065
EGF EGF: Pro-epidermal growth factor precursor 0.123 0.065
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.072
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.123 0.072
EPOR EPOR: Erythropoietin receptor precursor 0.123 0.072
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.123 0.126
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.123 0.072
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.123 0.0727
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.123 0.065
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.123 0.081
F3 F3: Tissue factor precursor 0.123 0.065
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.123 0.100
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.202
CHN1 CHN1, ARHGAP2, CHN: N-chimaerin 0.115 0.158
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.114 0.113
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.113 0.171
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.111 0.065
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.111 0.520
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.111 0.586
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.111 0.520
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.111 0.577
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.111 0.520
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.111 0.577
KIT KIT: Mast/stem cell growth factor receptor precursor 0.111 0.655
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.111 1.01
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
MAPK15 N/A 0.109 0.165
NF2 NF2, SCH: Merlin 0.109 0.165
PPEF1 N/A 0.109 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
PSCD2 N/A 0.109 0.165
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
CNN2 CNN2: Calponin-2 0.109 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.109 0.166
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.274
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.109 0.202
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.109 0.081
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.202
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.109 0.340
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.109 0.274
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.109 0.100
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.072
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.109 0.081
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.307
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.109 0.126
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.109 0.100
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.109 0.058
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.109 0.0446
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.109 0.100
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.109 0.166
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.109 0.274
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.109 0.065
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.109 1.19
GPA33 GPA33: Cell surface A33 antigen precursor 0.109 0.100
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.109 0.561
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.109 0.065
LILRB1 N/A 0.109 0.274
PVR PVR, PVS: Poliovirus receptor precursor 0.109 0.065
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.109 0.0727
INHA INHA: Inhibin alpha chain precursor 0.100 0.041
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.100 0.036
CP CP: Ceruloplasmin precursor 0.100 0.046
CTTN CTTN, EMS1: Src substrate cortactin 0.100 0.078
IRS2 IRS2: Insulin receptor substrate 2 0.100 0.152
F5 F5: Coagulation factor V precursor 0.100 0.051
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.100 0.041
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.098 0.202
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.098 0.340
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.098 0.561
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.274
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.098 0.065
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.098 0.340
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.098 0.340
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.098 0.072
CD7 CD7: T-cell antigen CD7 precursor 0.098 0.202
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.098 1.19
SORL1 SORL1: Sortilin-related receptor precursor 0.098 0.340
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.098 0.561
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.098 0.340
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.126
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.098 0.058
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.098 0.126
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.098 1.19
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.098 0.561
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.126
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.098 0.100
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.098 1.19
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.098 0.027
CRLF3 N/A 0.098 0.561
IL9R IL9R: Interleukin-9 receptor precursor 0.098 0.081
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.098 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.098 0.030
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.148
SNX3 N/A 0.098 0.148
ARHGEF7 N/A 0.098 0.148
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.098 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.098 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.148
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.098 0.030
ELMO1 N/A 0.098 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.098 0.148
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.098 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.098 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.148
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.097 0.655
DCC DCC: Netrin receptor DCC precursor 0.097 0.064
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.097 0.577
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.097 0.078
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.097 0.245
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.097 0.520
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.097 0.052
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.520
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.097 0.577
TNC TNC, HXB: Tenascin precursor 0.097 0.058
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.090
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.096 0.029
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.087
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.091 0.046
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.091 0.045
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.091 0.036
VWF VWF, F8VWF: von Willebrand factor precursor 0.090 0.037
PLD1 PLD1: Phospholipase D1 0.090 0.171
DLG2 DLG2: Disks large homolog 2 0.090 0.041
VIL2 N/A 0.090 0.372
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.090 0.097
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.090 0.372
SH3BP5 N/A 0.090 0.225
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.088 0.052
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.088 0.415
PTPRZ1 N/A 0.088 0.058
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.088 0.058
NEO1 NEO1, NGN: Neogenin precursor 0.088 0.065
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.088 0.655
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.086 0.030
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.083 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.109
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
EDA N/A 0.083 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.083 0.109
GAB2 N/A 0.081 0.191
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.081 0.123
CSPG2 N/A 0.081 0.0794
NDP NDP: Norrin precursor 0.081 0.036
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.081 0.109
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.081 0.307
IRS1 IRS1: Insulin receptor substrate 1 0.081 0.109
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.081 0.045
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.063
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.081 0.041
TSHB TSHB: Thyrotropin subunit beta precursor 0.081 0.041
GAB1 GAB1: GRB2-associated-binding protein 1 0.081 0.123
FSHB FSHB: Follitropin subunit beta precursor 0.081 0.045
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.081 0.152
S100A3 S100A3, S100E: Protein S100-A3 0.081 0.098
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.081 0.152
LHB LHB: Lutropin subunit beta precursor 0.081 0.045
SDC1 SDC1, SDC: Syndecan-1 precursor 0.080 0.032
GJA5 GJA5: Gap junction alpha-5 protein 0.0782 0.030
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.077 0.0453
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.077 0.037
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.075 0.041
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.098
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.044
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.073 0.088
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.073 0.041
RDX RDX: Radixin 0.073 0.088
FGF9 FGF9: Glia-activating factor precursor 0.073 0.041
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.073 0.037
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.073 0.111
STAM2 STAM2: Signal transducing adapter molecule 2 0.073 0.136
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.073 0.037
PLD2 PLD2: Phospholipase D2 0.073 0.111
DAB1 DAB1: Disabled homolog 1 0.073 0.088
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.073 0.088
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.073 0.099
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.073 0.111
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.073 0.136
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.073 0.041
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.073 0.041
TLN1 TLN1: Uncharacterized protein TLN1 0.073 0.372
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.073 0.136
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.073 0.037
S100A7 S100A7, PSOR1: Protein S100-A7 0.072 0.109
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.123
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.072 0.110
IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 0.072 0.051
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.072 0.174
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.123
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.515
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.072 0.045
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.072 0.051
F8 F8, F8C: Coagulation factor VIII precursor 0.072 0.036
TNNC1 TNNC1, TNNC: Troponin C, slow skeletal and cardiac muscles 0.072 0.037
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.416
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.072 0.191
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.416
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.072 1.50
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.072 0.041
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.515
VASP VASP: Vasodilator-stimulated phosphoprotein 0.072 0.416
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.072 0.0794
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.072 0.155
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.072 0.416
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.072 0.110
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.072 0.041
S100B S100B: Protein S100-B 0.072 0.098
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.072 0.251
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.109
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.069 0.041
NSBP1 NSBP1: Nucleosome-binding protein 1 0.0688 0.109
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.171
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.065 0.225
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.065 0.275
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.307
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.251
ROCK1 ROCK1: Rho-associated protein kinase 1 0.065 0.515
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.065 1.81
SNCB SNCB: Beta-synuclein 0.065 0.110
SPTAN1 N/A 0.065 0.098
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.065 0.140
GRLF1 N/A 0.065 0.123
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.065 0.515
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.065 0.251
STK16 N/A 0.065 0.251
TST TST: Thiosulfate sulfurtransferase 0.064 0.111
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.064 1.62
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.064 0.088
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.064 0.088
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.064 0.461
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.064 0.088
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.064 0.225
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.064 0.136
SPARC SPARC, ON: SPARC precursor 0.064 0.041
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.041
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.064 0.763
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.064 0.078
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.064 0.046
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.064 0.461
CHP CHP: Calcium-binding protein p22 0.064 0.136
MYL3 MYL3: Myosin light polypeptide 3 0.064 0.097
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.064 0.275
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.064 0.318
TTN N/A 0.064 0.097
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.064 0.225
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.064 0.763
PSCD4 PSCD4, CYT4: Cytohesin-4 0.064 0.461
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.064 0.097
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.064 0.225
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.064 1.62
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.064 0.171
CD2AP CD2AP: CD2-associated protein 0.064 0.461
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.064 0.275
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.064 0.275
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.064 0.225
TLN2 TLN2: Uncharacterized protein TLN2 0.064 0.078
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.064 0.275
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.064 0.136
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.064 0.461
SORBS3 SORBS3, SCAM1: Vinexin 0.064 0.097
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.064 0.088
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.064 0.041
FNBP1 N/A 0.064 1.62
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.064 0.461
GMIP GMIP: GEM-interacting protein 0.064 0.461
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.064 0.099
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.064 0.099
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.064 0.155
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.064 0.781
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.064 0.171
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.064 0.275
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.064 1.62
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.064 0.461
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.064 0.088
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.064 0.070
RPS6KB1 N/A 0.064 0.461
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.064 0.088
FGL2 FGL2: Fibroleukin precursor 0.064 0.046
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.361
LCP1 LCP1, PLS2: Plastin-2 0.064 1.62
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.064 0.056
HSP90AA1 Hsp89-alpha-delta-N 0.064 0.114
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.064 0.763
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.063 0.058
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.0727
TP73 TP73, P73: Tumor protein p73 0.063 0.072
GABRR1 N/A 0.062 0.033
RHO RHO, OPN2: Rhodopsin 0.062 0.029
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.062 0.033
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.062 0.029
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.062 0.029
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.062 0.057
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.098
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.062 0.098
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.098
CETN1 CETN1, CEN1, CETN: Centrin-1 0.062 0.098
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.060 0.046
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.058 1.62
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.058 0.099
MSN MSN: Moesin 0.058 0.461
PSD TYL: TYL protein 0.058 0.097
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.058 0.763
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.058 0.097
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.058 0.099
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.058 0.088
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.058 0.372
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.058 0.078
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.058 0.111
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.058 0.275
DOK1 DOK1: Docking protein 1 0.058 0.372
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.058 0.763
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.058 0.461
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.058 0.763
CXorf9 N/A 0.058 1.62
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.058 0.041
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.058 0.372
RASA3 RASA3: Ras GTPase-activating protein 3 0.058 0.225
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.058 0.461
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.058 0.275
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.058 0.136
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.058 0.275
ACTN1 ACTN1: Alpha-actinin-1 0.058 0.097
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.058 0.088
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.058 0.111
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.058 0.111
STMN1 STMN1, LAP18, OP18: Stathmin 0.058 0.136
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.057 0.046
HPN HPN, TMPRSS1: Serine protease hepsin 0.056 0.029
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.056 0.026
CD82 CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen 0.056 0.090
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.056 0.041
GLRA1 N/A 0.056 0.029
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.056 0.029
ITGAE ITGAE: Integrin alpha-E precursor 0.056 0.074
CD44 N/A 0.055 0.124
FADD FADD, MORT1: Protein FADD 0.055 0.124
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.055 0.081
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.055 0.072
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.054 0.136
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.053 0.070
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.052 0.049
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.052 0.04
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
C9orf88 N/A 0.051 0.051
IGHD N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
RAPH1 N/A 0.051 0.051
HLA-A N/A 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
UBAP2L N/A 0.051 0.051
KIAA1688 KIAA1688: KIAA1688 protein (Fragment) 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
IGHG1 N/A 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
SNX12 N/A 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
MARK2 N/A 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
PTPRA N/A 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
SPARCL1 SPARCL1: SPARC-like protein 1 precursor 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
IGHM N/A 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
PPP1R1B PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
ITIH3 ITIH3: Inter-alpha-trypsin inhibitor heavy chain H3 precursor 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
PPP1R14C PPP1R14C, KEPI: Protein phosphatase 1 regulatory subunit 14C 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NCAM1 N/A 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
SNX2 SNX2, TRG9: Sorting nexin-2 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.100
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.049 0.340
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.340
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.049 0.074
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.049 0.081
MT3 MT3: Metallothionein-3 0.049 0.037
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.049 0.081
CCR5 CCR5: CCR5 receptor (Fragment) 0.049 0.202
CD69 CD69: Early activation antigen CD69 0.049 0.0446
ATP2B1 N/A 0.049 0.037
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.083
MAP2K5 N/A 0.049 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.083
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.049 0.052
YWHAG YWHAG: 14-3-3 protein gamma 0.049 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
ITGB7 ITGB7: Integrin beta-7 precursor 0.049 0.227
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.049 0.029
GNAI2 Galphai2 protein 0.049 0.040
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.049 0.304
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.049 0.304
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.047 0.027
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.044
AQP4 AQP4: Aquaporin-4 0.047 0.036
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
LMO7 N/A 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
MLLT4 N/A 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
NF1 NF1: Neurofibromin 0.046 0.046
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.046 0.046
PPP1R14A PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.046 0.181
FKBP9 FKBP9, FKBP60, FKBP63: FK506-binding protein 9 precursor 0.046 0.041
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.046 0.245
ST8SIA4 ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe 0.045 0.0446
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.045 0.340
PLEK PLEK, P47: Pleckstrin 0.045 1.19
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.044 0.0818
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.136
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.044 0.032
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.075
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.075
TSC2 TSC2, TSC4: Tuberin 0.044 0.075
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.075
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.041 0.065
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.041 0.561
RYR2 RYR2: Ryanodine receptor 2 0.041 0.041
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.063
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.041 0.029
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.041 0.088
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.181
FKBP10 FKBP10, FKBP65, PSEC0056: FK506-binding protein 10 precursor 0.041 0.037
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.041 0.113
RYR1 0.041 0.037
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.041 1.07
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.064
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.041 0.065
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.083
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.039 0.046
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.0263
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.038 0.0338
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.038 0.0955
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.038 0.030
GAS2 GAS2: Growth arrest-specific protein 2 0.037 0.026
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.037 0.090
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.037 0.058
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.037 0.113
ST6GAL1 ST6GAL1, SIAT1: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltrans 0.037 0.040
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.037 0.245
SOS1 SOS1: Son of sevenless homolog 1 0.037 0.245
COTL1 COTL1, CLP: Coactosin-like protein 0.036 0.047
CFL2 CFL2: Cofilin-2 0.036 0.047
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.036 0.025
GSN GSN: Gelsolin precursor 0.036 0.047
SVIL SVIL: Supervillin 0.036 0.047
SDC4 SDC4: Syndecan-4 precursor 0.035 0.029
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.064
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.035 0.029
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.034 0.037
PEBP1 PEBP1, PBP, PEBP: Phosphatidylethanolamine-binding protein 1 0.034 0.0273
CAV1 CAV1, CAV: Caveolin-1 0.034 0.0273
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.034 0.030
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.034 0.086
CNN1 CNN1: Calponin-1 0.0338 0.030
PPP1R1A PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A 0.0338 0.030
CAV2 CAV2: Caveolin-2 0.0338 0.034
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.0338 0.034
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.069
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.033 0.069
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.033 0.097
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.033 0.069
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.033 0.044
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.033 0.188
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.032 0.049
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.260
COBL N/A 0.032 0.110
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.032 0.210
FLNA FLNA, FLN, FLN1: Filamin-A 0.032 0.052
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.032 0.036
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.032 0.087
KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 0.032 0.034
FUBP1 N/A 0.032 0.430
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.032 0.152
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 1.81
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.0308 0.026
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.0308 0.029
TSHR N/A 0.0308 0.029
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.0308 0.029
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.053
PPP1R14D PPP1R14D, GBPI: Protein phosphatase 1 regulatory subunit 14D 0.030 0.0273
TNN TNN: Tenascin-N precursor 0.030 0.042
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.030 0.098
CREB1 CREB1: cAMP response element-binding protein 0.030 0.044
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.098
CHAT CHAT: Choline O-acetyltransferase 0.030 0.030
C1QBP C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot 0.030 0.030
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.044
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.029 0.136
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.029 0.127
YWHAQ YWHAQ: 14-3-3 protein theta 0.029 0.0425
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.029 0.052
B2M B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro 0.029 0.076
PVALB PVALB: Parvalbumin alpha 0.029 0.033
TNNC2 TNNC2: Troponin C, skeletal muscle 0.029 0.037
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.029 0.139
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.029 0.233
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.029 0.086
PMP2 PMP2: Myelin P2 protein 0.029 0.044
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.029 0.114
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.029 0.044
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.029 0.233
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.029 0.097
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.099
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.029 0.188
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.029 0.461
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.029 0.385
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.136
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.029 0.188
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.029 0.063
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.099
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.029 0.276
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.029 0.139
CTPS CTPS: CTP synthase 1 0.029 0.139
PIK3R1 PIK3R1, GRB1: Phosphatidylinositol 3-kinase regulatory subunit alpha 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
BTK N/A 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
GRB10 Adapter protein (Fragment) 0.0288 0.0288
FGR FGR, RP1-159A19.2-007: Gardner-Rasheed feline sarcoma viral (Fragment) 0.0288 0.0288
SYK N/A 0.0288 0.0288
BLNK BLNK, SLP65, BASH: B-cell linker protein (Fragment) 0.0288 0.0288
DAPP1 DAPP1, BAM32, HSPC066: Dual adapter for phosphotyrosine and 3-phosphotyrosine an 0.0288 0.0288
INPP5D N/A 0.0288 0.0288
TENC1 N/A 0.0288 0.0288
TNS1 TNS1, TNS: Tensin-1 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
VAV3 VAV-like protein (Fragment) 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
BLNK N/A 0.0288 0.0288
SOCS6 SOCS6, CIS4, SOCS4: Suppressor of cytokine signaling 6 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK N/A 0.0288 0.0288
PIK3R3 PIK3R3: Phosphatidylinositol 3-kinase regulatory subunit gamma 0.0288 0.0288
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.049
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
TBXA2R TBXA2R: Thromboxane A2 receptor 0.028 0.04
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.028 0.067
GLRB GLRB: Glycine receptor subunit beta precursor 0.028 0.029
CDC37 CDC37: Hsp90 co-chaperone Cdc37 0.0273 0.143
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.0273 0.053
SPOCK2 SPOCK2, KIAA0275, UNQ269/PRO306, TICN2: Testican-2 precursor 0.0273 0.034
AQP2 AQP2: Aquaporin-2 0.027 0.035
VIL1 VIL1, VIL: Villin-1 0.027 0.035
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.027 0.385
AQP1 AQP1, CHIP28: Aquaporin-1 0.027 0.028
DBN1 DBN1, D0S117E: Drebrin 0.027 0.039
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
FGFR2 N/A 0.027 0.217
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0263 0.087
MDN1 MDN1, KIAA0301: Midasin 0.026 0.063
WASPIP N/A 0.026 1.62
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.026 0.046
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.026 0.385
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.026 0.078
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.026 0.069
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.026 0.038
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.026 0.233
ATM ATM: Serine-protein kinase ATM 0.026 0.372
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.026 0.227
FLII FLII, FLIL: Protein flightless-1 homolog 0.026 0.146
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.026 0.233
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.026 0.372
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.026 0.171
INPPL1 INPPL1, SHIP2: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 0.0258 0.0258
SOCS7 SOCS7, NAP4, SOCS6: Suppressor of cytokine signaling 7 0.0258 0.0258
FES N/A 0.0258 0.0258
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.025 0.037
RAP1GA1 N/A 0.025 0.033
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.0727
ETS2 ETS2: Protein C-ets-2 0.025 0.100
TOM1L1 TOM1L1, SRCASM: TOM1-like protein 1 0.025 0.029
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.025 0.148
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.044
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.098
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.044
0.228
Total Score 47.30