Home
Advanced Search
Help
Update History
Statistics
Downloads
The Barton Group
<<< Back to TAF6

Evidence of Interaction Between TAF6 and TAF9

The interaction score between TAF6 and TAF9 is 1.85E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TAF6 and TAF9 = 0.58

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 6.27E-3
Orthology
OrganismTAF6 OrthologueTAF9 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YGL112C 1 YMR236W 1
  • Y2H
  • Other
  • AffinityChromatography
  • AffinityCaptureMS
  • DosageRescue

Get References From PubMed
worm Q9GZI6 1 O45784 0.744
fly P49847 1 Q27272 0.681
  • Other

Get References From PubMed

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 3.01
Domains Domains present in TAF6 and TAF9:
Domains in TAF6Domains in TAF9
IPR009072 Histone-fold
IPR004823 TATA box binding protein associated factor (TAF)
IPR007124 Histone-fold/TFIID-TAF/NF-Y
IPR011442 DUF1546.
IPR009072 Histone-fold
IPR003162 Transcription factor TAFII-31
IPR007124 Histone-fold/TFIID-TAF/NF-Y

The Chi square scores for co-occurrence of domains that are present in TAF6 and TAF9 are listed below.

Domain 1Domain 2Chi Square
IPR007124 Histone-fold/TFIID-TAF/NF-Y IPR007124 Histone-fold/TFIID-TAF/NF-Y 33.1556
IPR009072 Histone-fold IPR007124 Histone-fold/TFIID-TAF/NF-Y 19.0387

The background colour of the table refers to:

  • Blue Domain is only present in TAF6
  • Yellow Domain is only present in TAF9
  • Green Domain is present in both TAF6 and TAF9

 0.027
Post-translational Modifications

Protein: TAF6

PTMResidueReference
Phosphorylation 653 PubMed, HPRD
Phosphoserine 653 HPRD

Protein: TAF9

PTMResidueReference
Localisation

Protein: TAF6

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: TAF9

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between TAF6 and TAF9 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TAF6 andTAF9. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TAF6 has 1055 interactors and TAF9 has 234 interactors of which there are 209 common interactors.

Common InteractorName of Common InteractorScore for TAF6-Interactor (?)Score for TAF9-Interactor (?)
TBP TBP, GTF2D1, TF2D, TFIID: TATA-box-binding protein 80.90 100.00
H2AFX H2AFX, H2AX: Histone H2A.x 72.80 0.044
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 45.20 0.044
TAF5 TAF5, TAF2D: Transcription initiation factor TFIID subunit 5 15.90 32.60
PCAF PCAF: Histone acetyltransferase PCAF 14.70 1.79
HIST1H2BG HIST1H2BC, H2BFL, HIST1H2BE, H2BFH, HIST1H2BF, H2BFG, HIST1H2BG, H2BFA, HIST1H2B 9.63 0.028
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 9.09 0.028
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 7.38 0.360
TAF12 TAF12, TAF15, TAF2J, TAFII20: Transcription initiation factor TFIID subunit 12 7.31 80.90
CHD1 CHD1: Chromodomain-helicase-DNA-binding protein 1 5.20 0.143
TAF13 TAF13, TAF2K, TAFII18: Transcription initiation factor TFIID subunit 13 4.16 5.83
TAF7 TAF7, TAF2F, TAFII55: Transcription initiation factor TFIID subunit 7 2.36 3.20
H2BFS H2BFS: Histone H2B type F-S 2.36 0.036
HIST1H2BK HIST1H2BK, H2BFT, HIRIP1: Histone H2B type 1-K 2.36 0.036
HIST1H2AB N/A 1.46 0.036
HIST1H2AG HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2A 1.46 0.028
HIST1H2BJ HIST1H2BJ, H2BFR: Histone H2B type 1-J 1.17 0.028
TRRAP TRRAP, PAF400: Transformation/transcription domain-associated protein 1.15 0.593
BRD7 BRD7, BP75, CELTIX1: Bromodomain-containing protein 7 0.890 1.82
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.852 0.083
ENY2 ENY2, DC6: Enhancer of yellow 2 transcription factor homolog 0.593 0.593
USP22 0.593 0.593
TAF2 TAF2, CIF150, TAF2B: Transcription initiation factor TFIID subunit 2 0.593 0.593
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.515 0.067
TCOF1 N/A 0.515 0.067
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.461 0.074
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.461 0.123
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.430 0.0255
CENPA CENPA: Histone H3-like centromeric protein A 0.416 0.050
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.416 0.067
TAF1L TAF1L: Transcription initiation factor TFIID 210 kDa subunit 0.390 0.390
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.372 0.074
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.372 0.074
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.372 0.060
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.372 0.074
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.372 0.044
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.372 0.060
CDC20 CDC20: Cell division cycle protein 20 homolog 0.372 0.074
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.372 0.123
TAF1 N/A 0.354 0.354
SUPT3H N/A 0.354 0.354
TADA2L TADA2L, KL04P: Transcriptional adapter 2-like 0.326 0.408
TAF7L TAF7L, GHc-521F8.1-003: Transcription initiation factor TFIID subunit 7-like pro 0.326 0.408
GNB2L1 Lung cancer oncogene 7 0.307 0.067
PTMA N/A 0.307 0.083
RANBP9 RANBP9, RANBPM: Ran-binding protein 9 0.275 0.123
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.275 0.044
CHD2 N/A 0.261 0.261
WDR1 N/A 0.251 0.050
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.251 0.067
CBX3 CBX3: Chromobox protein homolog 3 0.233 0.038
COPA COPA: Coatomer subunit alpha 0.225 0.036
BRPF1 BRPF1, BR140: Peregrin 0.225 0.044
COPB2 COPB2: Coatomer subunit beta' 0.225 0.044
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.225 0.036
SEC31L1 N/A 0.225 0.060
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.225 0.036
PHF10 N/A 0.225 0.060
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.225 0.036
NUP214 N/A 0.191 0.041
CD2AP CD2AP: CD2-associated protein 0.181 0.047
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.181 0.035
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.171 0.036
CORO1C CORO1C, CRNN4: Coronin-1C 0.171 0.044
SOS1 SOS1: Son of sevenless homolog 1 0.171 0.036
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.171 0.036
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.171 0.044
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.165 0.027
WDR54 N/A 0.165 0.027
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.165 0.027
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.165 0.027
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.165 0.027
UHRF1 0.165 0.027
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.136 0.028
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.136 0.028
RBBP4 RBBP4, RBAP48: Histone-binding protein RBBP4 0.126 0.123
Nle NLE1, HUSSY-07: Notchless protein homolog 1 0.126 0.036
NULL N/A 0.119 0.119
BP75 N/A 0.119 0.119
NULL N/A 0.119 0.119
NULL N/A 0.119 0.119
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.113 0.029
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.113 0.035
DYNC1I2 N/A 0.111 0.028
NHP2L1 NHP2L1: NHP2-like protein 1 0.100 0.059
ETF1 ETF1, ERF1, RF1, SUP45L1: Eukaryotic peptide chain release factor subunit 1 0.100 0.059
STAM2 STAM2: Signal transducing adapter molecule 2 0.090 0.047
NAP1L4 NAP1L4, NAP2: Nucleosome assembly protein 1-like 4 0.083 0.067
FLJ10439 WDR74, NSA1: WD repeat-containing protein 74 0.074 0.060
BOP1 BOP1, KIAA0124: Ribosome biogenesis protein BOP1 0.074 0.060
NUP43 N/A 0.074 0.074
WDR12 WDR12: WD repeat-containing protein 12 0.074 0.074
PWP2H PWP2, PWP2H: Periodic tryptophan protein 2 homolog 0.074 0.044
BRD9 N/A 0.071 0.071
USP51 USP51: Ubiquitin carboxyl-terminal hydrolase 51 0.071 0.071
TBPL2 0.071 0.071
SEC13L1 SEC13, D3S1231E, SEC13L1, SEC13R: Protein SEC13 homolog 0.067 0.067
GTF3C2 GTF3C2, KIAA0011: General transcription factor 3C polypeptide 2 0.067 0.067
WDR18 N/A 0.060 0.060
TAF11 TAF11, TAF2I, PRO2134: Transcription initiation factor TFIID subunit 11 0.060 0.060
PRPF4 PRPF4, PRP4: U4/U6 small nuclear ribonucleoprotein Prp4 0.060 0.074
WDR77 WDR77, HKMT1069, hCG_39991: Androgen receptor cofactor p44 0.060 0.060
SF3B3 N/A 0.060 0.060
WDR57 WDR57, PRP8BP, SFP38: WD repeat-containing protein 57 0.060 0.074
AAMP AAMP: Angio-associated migratory cell protein 0.060 0.036
STRAP STRAP, MAWD, UNRIP: Serine-threonine kinase receptor-associated protein 0.060 0.074
C20orf11 C20orf11: Protein C20orf11 0.060 0.044
CXXC1 CXXC1, CGBP, PCCX1, PHF18: CpG-binding protein 0.060 0.044
NUP37 NUP37: Nucleoporin Nup37 0.060 0.123
H2AFZ H2AFZ, H2AZ: Histone H2A.Z 0.060 0.074
SMYD3 SMYD3, ZMYND1, ZNFN3A1: SET and MYND domain-containing protein 3 0.060 0.036
RBBP7 RBBP7, RBAP46: Histone-binding protein RBBP7 0.060 0.074
WDR68 WDR68, HAN11: WD repeat-containing protein 68 0.060 0.060
POLE3 POLE3, CHRAC17: DNA polymerase epsilon subunit 3 0.060 0.074
WDR8 WDR8: WD repeat-containing protein 8 0.050 0.050
GNB1L GNB1L, GY2, FKSG1, KIAA1645, WDR14: Guanine nucleotide-binding protein subunit b 0.050 0.041
DDB2 DDB2: DNA damage-binding protein 2 0.050 0.050
WDR41 N/A 0.050 0.083
BRD1 BRD1, BRL, BRPF2: Bromodomain-containing protein 1 0.050 0.067
FBXW2 FBXW2, FBW2, FWD2: F-box/WD repeat-containing protein 2 0.050 0.067
FLJ22318 N/A 0.050 0.083
SECISBP2 SECISBP2, SBP2: SECIS-binding protein 2 0.047 0.047
PRP19 PRPF19, NMP200, PRP19, SNEV: Pre-mRNA-processing factor 19 0.047 0.047
NUTF2 NUTF2, NTF2: Nuclear transport factor 2 0.047 0.035
WDR3 WDR3: WD repeat-containing protein 3 0.044 0.074
PPP2R2A PPP2R2A: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alp 0.044 0.074
TRIM33 TRIM33, KIAA1113, RFG7, TIF1G: E3 ubiquitin-protein ligase TRIM33 0.044 0.060
INTS12 INTS12, PHF22, SBBI22: Integrator complex subunit 12 0.044 0.074
TAF4 TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135: Transcription initiation factor 0.044 0.044
SMYD2 SMYD2: SET and MYND domain-containing protein 2 0.044 0.044
TBPL1 TBPL1, TLP, TLP21, TRF2: TATA box-binding protein-like protein 1 0.044 0.074
ARPC1A ARPC1A, SOP2L: Actin-related protein 2/3 complex subunit 1A 0.044 0.036
RAE1 RAE1, MRNP41: mRNA export factor 0.044 0.074
THRAP5 MED16, DRIP92, THRAP5: Mediator of RNA polymerase II transcription subunit 16 0.044 0.028
WDR39 CIAO1, WDR39: Protein CIAO1 0.044 0.044
WIPI2 WIPI2, CGI-50: WD repeat domain phosphoinositide-interacting protein 2 0.044 0.060
RNU3IP2 RRP9, RNU3IP2, U355K: U3 small nucleolar RNA-interacting protein 2 0.044 0.060
LRBA LRBA, BGL, CDC4L, LBA: Lipopolysaccharide-responsive and beige-like anchor prote 0.044 0.060
TSSC1 TSSC1: Protein TSSC1 0.044 0.060
MTF2 MTF2: Metal-response element-binding transcription factor 2 0.044 0.074
EML3 EML3: Echinoderm microtubule-associated protein-like 3 0.044 0.036
SUV39H1 SUV39H1, SUV39H: Histone-lysine N-methyltransferase SUV39H1 0.044 0.036
CDC40 CDC40, EHB3, PRP17, PRPF17: Pre-mRNA-processing factor 17 0.036 0.060
DDB1 DDB1, XAP1: DNA damage-binding protein 1 0.036 0.028
AAAS AAAS, ADRACALA, GL003: Aladin 0.036 0.044
WDR37 N/A 0.036 0.028
PIK3R4 PIK3R4: Phosphoinositide 3-kinase regulatory subunit 4 0.036 0.044
GRWD1 GRWD1, GRWD, WDR28: Glutamate-rich WD repeat-containing protein 1 0.036 0.044
KATNB1 KATNB1: Katanin p80 WD40-containing subunit B1 0.036 0.036
SETDB1 SETDB1, KIAA0067: Histone-lysine N-methyltransferase SETDB1 0.036 0.036
FBXL11 FBXL11, FBL7, JHDM1A, KIAA1004: JmjC domain-containing histone demethylation pro 0.036 0.036
WDR48 WDR48, KIAA1449: WD repeat-containing protein 48 0.036 0.060
WDR45L N/A 0.036 0.028
JMJD2C JMJD2C, GASC1, JHDM3C, KIAA0780: JmjC domain-containing histone demethylation pr 0.036 0.044
DR1 DR1: TATA-binding protein-associated phosphoprotein 0.036 0.074
WDR67 WDR67: WD repeat-containing protein 67 0.036 0.044
CORO7 CORO7: Coronin-7 0.036 0.044
WDR42A N/A 0.036 0.028
NBEAL2 N/A 0.036 0.028
ING2 ING2, ING1L: Inhibitor of growth protein 2 0.036 0.060
SSBP2 SSBP2, SSDP2: Single-stranded DNA-binding protein 2 0.036 0.036
NSD1 NSD1, ARA267: Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 0.036 0.044
MYST3 MYST3, MOZ, RUNXBP2, ZNF220: Histone acetyltransferase MYST3 0.036 0.044
RPL30 RPL30: 60S ribosomal protein L30 0.035 0.047
RPL7A RPL7A, SURF-3, SURF3: 60S ribosomal protein L7a 0.035 0.059
NOLA2 NOLA2, NHP2, HSPC286: H/ACA ribonucleoprotein complex subunit 2 0.035 0.035
RPP38 RPP38: Ribonuclease P protein subunit p38 0.032 0.039
PHF20 PHF20, C20orf104, GLEA2, HCA58, NZF, TZP: PHD finger protein 20 0.032 0.039
OFD1 OFD1, CXorf5: Oral-facial-digital syndrome 1 protein 0.032 0.053
CBFA2T3 MTGR2: MTG8-related protein (Fragment) 0.0308 0.0308
SP140 SP140, LYSP100: Nuclear body protein SP140 0.0308 0.041
PRDM4 PRDM4, PFM1: PR domain zinc finger protein 4 0.0308 0.041
NPAT Similar to nuclear protein, ataxia-telangiectasia locus (Fragment) 0.0308 0.041
SP110 SP110: Sp110 nuclear body protein 0.0308 0.041
PHF11 RP11-185C18.3, PHF11, RP11-185C18.3-001, hCG_28346: OTTHUMP00000018414 0.0308 0.050
NFYB NFYB, HAP3: Nuclear transcription factor Y subunit beta 0.028 0.036
CORO1A CORO1A, CORO1: Coronin-1A 0.028 0.036
JARID1B JARID1B, PLU1, RBBP2H1: Histone demethylase JARID1B 0.028 0.060
PAFAH1B1 PAFAH1B1, LIS1, MDCR, MDS, PAFAHA: Platelet-activating factor acetylhydrolase IB 0.028 0.028
SMCY JARID1D, HY, HYA, KIAA0234, SMCY: Histone demethylase JARID1D 0.028 0.028
WDR26 WDR26, CDW2, PRO0852, MIP2: WD repeat-containing protein 26 0.028 0.044
MLL5 MLL5: Myeloid/lymphoid or mixed-lineage leukemia 5 0.027 0.027
ERCC8 ERCC8, CKN1, CSA: DNA excision repair protein ERCC-8 0.027 0.027
TAF5L TAF5L, PAF65B: TAF5-like RNA polymerase II p300/CBP-associated factor-associated 0.027 0.027
PRDM13 PRDM13, PFM10: PR domain zinc finger protein 13 0.027 0.027
TLE6 TLE6: Transducin-like enhancer protein 6 0.027 0.027
RFWD2 RFWD2, COP1, RNF200: E3 ubiquitin-protein ligase RFWD2 0.027 0.027
SETD7 SETD7, KIAA1717, SET7: Histone-lysine N-methyltransferase, H3 lysine-4 specific 0.027 0.027
WDR72 N/A 0.027 0.027
UHRF2 UHRF2, NIRF, RNF107: E3 ubiquitin-protein ligase UHRF2 0.027 0.027
PRDM14 PRDM14: PR domain zinc finger protein 14 0.027 0.027
PHF1 N/A 0.027 0.027
HIST1H2AD HIST1H2AD, H2AFG: Histone H2A type 1-D 0.027 0.027
PHF13 PHF13: PHD finger protein 13 0.027 0.027
FBXW8 FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6: F-box/WD repeat-containing protein 8 0.027 0.027
TCF19 TCF19, SC1: Transcription factor 19 0.027 0.027
BRWD1 N/A 0.027 0.027
H2AFY2 H2AFY2, MACROH2A2: Core histone macro-H2A.2 0.027 0.027
WDR17 N/A 0.027 0.027
WDR34 N/A 0.027 0.027
PYGO2 PYGO2, PP7910: Pygopus homolog 2 0.027 0.027
OGG1 N/A 0.027 0.027
PHF12 PHF12, KIAA1523: PHD finger protein 12 0.027 0.027
KIF21A N/A 0.027 0.027
WHSC1 WHSC1, KIAA1090, MMSET, NSD2, TRX5: Probable histone-lysine N-methyltransferase 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
WDR53 N/A 0.027 0.027
PHF6 PHF6, KIAA1823: PHD finger protein 6 0.027 0.027
NEDD1 N/A 0.027 0.027
0.572
Total Score 1.85E4