<<< Back to CHMP4C

Evidence of Interaction Between CHMP4C and VPS4A

The interaction score between CHMP4C and VPS4A is 821.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

N/A
Orthology
OrganismCHMP4C OrthologueVPS4A OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YLR025W 0.279 YPR173C 0.489
  • Y2H
  • Other
  • AffinityCaptureMS

Get References From PubMed

worm Q18886 0.157 Q9BL83 0.523
fly Q8T0Q4 0.246 Q9Y162 0.137

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.064
Domains No domains were used in calculating likelihood of interaction 0.141
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: CHMP4C

LocalisationReference
Cytosol HPRD
Cytoplasm HPRD

Protein: VPS4A

LocalisationReference
Nucleus HPRD
Endosome HPRD
Vacuole HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between CHMP4C and VPS4A that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CHMP4C andVPS4A. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CHMP4C has 25 interactors and VPS4A has 89 interactors of which there are 15 common interactors.

Common InteractorName of Common InteractorScore for CHMP4C-Interactor (?)Score for VPS4A-Interactor (?)
CHMP4A N/A 319.00 20.80
CHMP6 CHMP6, VPS20: Charged multivesicular body protein 6 319.00 12.40
CHMP4B CHMP4B, C20orf178, SHAX1: Charged multivesicular body protein 4b 319.00 3.58
VPS4B VPS4B, SKD1, VPS42: Vacuolar protein sorting-associating protein 4B 169.00 0.044
VPS24 VPS24, CHMP3, CGI-149, NEDF: Charged multivesicular body protein 3 169.00 0.490
CHMP2A CHMP2A, BC2, CHMP2: Charged multivesicular body protein 2a 12.60 0.317
CHMP1B CHMP1B, C18orf2: Charged multivesicular body protein 1b 0.265 0.353
CHMP7 CHMP7: Charged multivesicular body protein 7 0.265 0.261
CHMP5 CHMP5, C9orf83, CGI-34, SNF7DC2, HSPC177, PNAS-2, PNAS-114: Charged multivesicul 0.237 0.191
CHMP2B CHMP2B, CGI-84: Charged multivesicular body protein 2b 0.237 0.234
PDCD6IP PDCD6IP, AIP1, ALIX, KIAA1375: Programmed cell death 6-interacting protein 0.143 0.221
LOC283683 N/A 0.064 0.064
FBXO34 CGI-301: Protein CGI-301 0.0288 0.0288
PCOLN3 CHMP1A, CHMP1, KIAA0047, PCOLN3, PRSM1: Charged multivesicular body protein 1a 0.0288 0.0288
SRPR SRPR: Uncharacterized protein SRPR 0.027 0.050
0.572
Total Score 821.00