<<< Back to PSMD11

Evidence of Interaction Between PSMD11 and PSMD13

The interaction score between PSMD11 and PSMD13 is 280.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between PSMD11 and PSMD13 = 0.78

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.013
Orthology
OrganismPSMD11 OrthologuePSMD13 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YDL097C 1 YDR427W 1
  • Other
  • AffinityCaptureMS
  • CoPurification

Get References From PubMed

worm Q20938 1 Q22253 1
fly Q9V3V4 1 Q9V469 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.593
Domains Domains present in PSMD11 and PSMD13:
Domains in PSMD11Domains in PSMD13
IPR000717 Proteasome component region PCI
IPR011990 TPR-like_helical.
IPR013143 PAM.
IPR000717 Proteasome component region PCI

The Chi square scores for co-occurrence of domains that are present in PSMD11 and PSMD13 are listed below.

Domain 1Domain 2Chi Square
IPR000717 Proteasome component region PCI IPR000717 Proteasome component region PCI 290.844
IPR011990 TPR-like_helical. IPR000717 Proteasome component region PCI 11.6549

The background colour of the table refers to:

  • Blue Domain is only present in PSMD11
  • Yellow Domain is only present in PSMD13
  • Green Domain is present in both PSMD11 and PSMD13

0.265
Post-translational Modifications

Protein: PSMD11

PTMResidueReference
Acetylation 2 PubMed, HPRD
N-acetylalanine 1 HPRD

Protein: PSMD13

PTMResidueReference
Localisation

Protein: PSMD11

LocalisationReference
Cytosol HPRD
Cytoplasm HPRD

Protein: PSMD13

LocalisationReference
Cytosol HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PSMD11 and PSMD13 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PSMD11 andPSMD13. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PSMD11 has 1005 interactors and PSMD13 has 181 interactors of which there are 142 common interactors.

Common InteractorName of Common InteractorScore for PSMD11-Interactor (?)Score for PSMD13-Interactor (?)
PSMD12 PSMD12: 26S proteasome non-ATPase regulatory subunit 12 628.00 116.00
PSMD14 PSMD14, POH1: 26S proteasome non-ATPase regulatory subunit 14 363.00 34.70
PSMD3 PSMD3: 26S proteasome non-ATPase regulatory subunit 3 323.00 195.00
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 60.10 2.15
PSMD6 PSMD6, KIAA0107, PFAAP4: 26S proteasome non-ATPase regulatory subunit 6 51.50 51.50
PSMD7 PSMD7, MOV34L: 26S proteasome non-ATPase regulatory subunit 7 35.20 179.00
PSMC1 PSMC1: 26S protease regulatory subunit 4 34.20 3.89
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 34.20 1.82
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 20.60 0.890
COPS5 COPS5, CSN5, JAB1: COP9 signalosome complex subunit 5 7.07 0.133
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 6.03 1.22
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 3.64 0.739
SHFM1 SHFM1, DSS1, SHFDG1: 26 proteasome complex subunit DSS1 3.05 3.05
PSMD8 3.05 3.05
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 2.93 1.22
RAD23B RAD23B: UV excision repair protein RAD23 homolog B 1.82 1.82
PSMC3 PSMC3, TBP1: 26S protease regulatory subunit 6A 1.82 1.82
PSMA7 PSMA7: Proteasome subunit alpha type-7 1.82 3.89
PSMC6 PSMC6, SUG2: 26S protease regulatory subunit S10B 1.82 1.82
PSMB2 PSMB2: Proteasome subunit beta type-2 1.82 1.82
USP14 USP14, TGT: Ubiquitin carboxyl-terminal hydrolase 14 1.82 1.10
RP11-98F14.6 N/A 1.53 0.0288
EIF3S5 N/A 1.39 0.133
EIF3S10 EIF3S10, KIAA0139: Eukaryotic translation initiation factor 3 subunit 10 1.22 2.60
hfl-B5 PCID1, EIF3M, GA17, hfl-B5, hCG_27316: PCI domain containing 1 1.22 1.22
COPS7B COPS7B, CSN7B: COP9 signalosome complex subunit 7b 1.22 1.22
COPS2 N/A 1.22 1.22
KIAA0368 ECM29, KIAA0368: Proteasome-associated protein ECM29 homolog 1.15 0.593
PSMD2 PSMD2, TRAP2: 26S proteasome non-ATPase regulatory subunit 2 1.10 1.10
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.852 0.083
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.763 0.123
CDC23 CDC23: Cell division cycle protein 23 homolog 0.763 0.123
COPS4 COPS4, CSN4: COP9 signalosome complex subunit 4 0.739 0.596
TP53 TP53, P53: Cellular tumor antigen p53 0.503 0.0968
WDR71 WDR71, PAAF1: Proteasomal ATPase-associated factor 1 0.494 0.364
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.461 0.074
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.461 0.074
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.440 0.0471
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.394 0.042
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.372 0.074
KIAA1012 KIAA1012: Protein TRS85 homolog 0.372 0.123
COPE COPE: Coatomer subunit epsilon 0.372 0.074
PSMC5 PSMC5, SUG1: 26S protease regulatory subunit 8 0.354 0.354
PSMC4 PSMC4, MIP224, TBP7: 26S protease regulatory subunit 6B 0.354 0.354
PSMD10 PSMD10: 26S proteasome non-ATPase regulatory subunit 10 0.354 0.354
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.304 0.047
CUL5 CUL5, VACM1: Cullin-5 0.304 0.059
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.287 0.137
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.275 0.060
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.275 0.044
STAT6 STAT6: Signal transducer and activator of transcription 6 0.275 0.074
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.275 0.060
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.275 0.044
HD HD, IT15: Huntingtin 0.260 0.0255
PTGES3 PTGES3, P23, TEBP: Prostaglandin E synthase 3 0.241 0.027
COPS7A COPS7A, CSN7A, DERP10: COP9 signalosome complex subunit 7a 0.237 0.237
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.233 0.038
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.225 0.028
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.225 0.036
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.225 0.036
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.225 0.044
FKBP4 FKBP4: FK506-binding protein 4 0.225 0.028
AIP AIP, XAP2: AH receptor-interacting protein 0.225 0.044
C20orf116 C20orf116: Uncharacterized protein C20orf116 precursor 0.217 0.217
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.185 0.042
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.185 0.042
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.181 0.035
NASP NASP: Nuclear autoantigenic sperm protein 0.165 0.027
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.152 0.0308
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.126 0.060
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.125 0.0471
CUL2 CUL2: Cullin-2 0.123 0.0968
FAM82B FAM82B, CGI-90: Protein FAM82B 0.123 0.123
GTF3C3 GTF3C3: General transcription factor 3C polypeptide 3 0.123 0.123
SRP72 CaM kinase II isoform 0.123 0.263
LRPPRC 0.123 0.074
CSTF3 CSTF3: Cleavage stimulation factor 77 kDa subunit 0.123 0.074
TOMM70A TOMM70A, KIAA0719: Mitochondrial precursor proteins import receptor 0.123 0.074
NULL N/A 0.119 0.119
NULL N/A 0.119 0.119
NULL N/A 0.119 0.119
NULL Uncharacterized protein ENSP00000325770 0.119 0.119
RAD23A RAD23A: UV excision repair protein RAD23 homolog A 0.108 0.108
FANCG FANCG, XRCC9: Fanconi anemia group G protein 0.083 0.083
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.078 0.366
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.076 0.044
TTC4 TTC4, My044: Tetratricopeptide repeat protein 4 0.074 0.074
ST13 ST13, FAM10A1, HIP, SNC6: Hsc70-interacting protein 0.074 0.074
HCA66 UTP6, C17orf40, HCA66, MHAT: U3 small nucleolar RNA-associated protein 6 homolog 0.074 0.074
EIF3S6IP N/A 0.074 0.123
TTC1 TTC1, TPR1: Tetratricopeptide repeat protein 1 0.074 0.074
PRPF6 PRPF6, C20orf14: Pre-mRNA-processing factor 6 0.074 0.074
PSMA8 PSMA8, PSMA7L: Proteasome subunit alpha type-7-like 0.071 0.071
SAMD9 SAMD9, C7orf5, DRIF1, KIAA2004, OEF1: Sterile alpha motif domain-containing prot 0.067 0.083
ZC3H7A ZC3H7A, ZC3H7, HSPC055, ZC3HDC7: Zinc finger CCCH domain-containing protein 7A 0.067 0.083
NASP N/A 0.061 0.037
SMYD2 SMYD2: SET and MYND domain-containing protein 2 0.060 0.060
KIAA0372 TTC37, KIAA0372: Tetratricopeptide repeat protein 37 0.060 0.060
CUL4A N/A 0.059 0.0968
TTK TTK, MPS1L1: Dual specificity protein kinase TTK 0.059 0.047
CUL1 CUL1: Cullin-1 0.059 0.047
BRCC3 BRCC3, C6.1A, CXorf53: BRCA1/BRCA2-containing complex subunit 3 0.053 0.072
IFIT3 IFIT3, IFI60, IFIT4: Interferon-induced protein with tetratricopeptide repeats 3 0.050 0.050
CUL7 CUL7, KIAA0076: Cullin-7 0.050 0.050
COPS6 COPS6, CSN6, HVIP: COP9 signalosome complex subunit 6 0.0479 0.065
T T: Brachyury protein 0.047 0.035
FIS1 FIS1, TTC11, CGI-135: Mitochondrial fission 1 protein 0.046 0.029
PPP5C PPP5C, PPP5: Serine/threonine-protein phosphatase 5 0.044 0.036
APPBP2 APPBP2, KIAA0228, PAT1: Amyloid protein-binding protein 2 0.044 0.036
XAB2 XAB2, HCNP, PP3898, KIAA1177: XPA-binding protein 2 0.044 0.060
TTC17 TTC17: Tetratricopeptide repeat protein 17 0.044 0.060
NULP1 TCF25, KIAA1049, FKSG26, NULP1: Transcription factor 25 0.044 0.060
CAPN7 CAPN7, PALBH: Calpain-7 0.044 0.060
COPS8 COPS8, CSN8: COP9 signalosome complex subunit 8 0.044 0.033
SFRS3 SFRS3, SRP20: Splicing factor, arginine/serine-rich 3 0.042 0.042
NONO NONO, NRB54: Non-POU domain-containing octamer-binding protein 0.042 0.042
CABIN1 CABIN1, KIAA0330: Calcineurin-binding protein Cabin 1 0.041 0.041
TOMM34 TOMM34: Mitochondrial import receptor subunit TOM34 0.041 0.0308
TTC3 TTC3, RNF105, TPRD: Tetratricopeptide repeat protein 3 0.041 0.0308
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.040 0.123
PARC RP3-330M21.2, PARC, RP3-330M21.2-001, hCG_1818381: OTTHUMP00000016423 0.039 0.039
TTC13 TTC13, RP11-99J16__B.1-001: Tetratricopeptide repeat domain 13 0.039 0.053
DNAJC3 DNAJC3, P58IPK, PRKRI: DnaJ homolog subfamily C member 3 0.036 0.044
KIAA0103 TTC35, KIAA0103: Tetratricopeptide repeat protein 35 0.036 0.028
BBS4 N/A 0.036 0.036
CDC27 CDC27, D0S1430E, D17S978E: Cell division cycle protein 27 homolog 0.036 0.044
ANAPC2 ANAPC2, APC2, KIAA1406: Anaphase-promoting complex subunit 2 0.035 0.047
GPSM2 GPSM2, RP11-475E11.4-001, hCG_39913: G-protein signalling modulator 2 0.035 0.035
VPS11 VPS11, RNF108, PP3476: Vacuolar protein sorting-associated protein 11 homolog 0.035 0.035
FBXO9 FBXO9, FBX9, VCIA1: F-box only protein 9 0.0308 0.041
GPS1 N/A 0.0288 0.0288
PSMD3 Proteasome subunit p58 0.0288 0.0288
RELB RELB: Transcription factor RelB 0.029 0.029
TTC15 TTC15, CGI-87: Tetratricopeptide repeat protein 15 0.028 0.036
BUB3 N/A 0.027 0.027
NPHP3 NPHP3, KIAA2000: Nephrocystin-3 0.027 0.027
IFIT5 IFIT5, RI58: Interferon-induced protein with tetratricopeptide repeats 5 0.027 0.027
TTC16 TTC16: Tetratricopeptide repeat protein 16 0.027 0.027
F8A1 F8A1, F8A: Factor VIII intron 22 protein 0.027 0.027
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.0262 0.042
C11orf58 SMAP, C11orf58: Small acidic protein 0.025 0.027
2.15E-3
Total Score 280.00