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Evidence of Interaction Between PSMA2 and PLK1

The interaction score between PSMA2 and PLK1 is 1.58E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismPSMA2 OrthologuePLK1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YML092C 1 YMR001C 1
worm Q27488 1 P34331 1
worm Q27488 1 Q9N2L7 0.33
fly P40301 1 P52304 1
  • Y2H

Get References From PubMed

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.177
Domains Domains present in PSMA2 and PLK1:
Domains in PSMA2Domains in PLK1
IPR001353 20S proteasome, A and B subunits
IPR000426 Proteasome alpha-subunit
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR000959 POLO box duplicated region

The Chi square scores for co-occurrence of domains that are present in PSMA2 and PLK1 are listed below.

Domain 1Domain 2Chi Square
IPR001353 20S proteasome, A and B subunits IPR000959 POLO box duplicated region 1222.5
IPR000426 Proteasome alpha-subunit IPR000959 POLO box duplicated region 295.276
IPR001353 20S proteasome, A and B subunits IPR002290 Serine/threonine protein kinase 30.6917
IPR001353 20S proteasome, A and B subunits IPR008271 Serine/threonine protein kinase, active site 19.7897
IPR001353 20S proteasome, A and B subunits IPR011009 Protein kinase-like 12.4605
IPR000426 Proteasome alpha-subunit IPR002290 Serine/threonine protein kinase 6.34315
IPR001353 20S proteasome, A and B subunits IPR000719 Protein kinase 4.69912
IPR000426 Proteasome alpha-subunit IPR008271 Serine/threonine protein kinase, active site 3.35494
IPR000426 Proteasome alpha-subunit IPR011009 Protein kinase-like 1.52636
IPR000426 Proteasome alpha-subunit IPR000719 Protein kinase 0.0968492

The background colour of the table refers to:

  • Blue Domain is only present in PSMA2
  • Yellow Domain is only present in PLK1
  • Green Domain is present in both PSMA2 and PLK1

 0.980
Post-translational Modifications

Protein: PSMA2

PTMResidueReference
Phosphotyrosine 23 HPRD
Phosphotyrosine 97 HPRD

Protein: PLK1

PTMResidueReference
Phosphorylation 87 PubMed, HPRD
Phosphorylation 210 PubMed, HPRD
Phosphorylation 326 PubMed, HPRD
Phosphoserine 137 PubMed, HPRD
Phosphoserine 335 HPRD
Phosphothreonine 210 HPRD
Localisation

Protein: PSMA2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: PLK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PSMA2 and PLK1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PSMA2 andPLK1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PSMA2 has 927 interactors and PLK1 has 1428 interactors of which there are 602 common interactors.

Common InteractorName of Common InteractorScore for PSMA2-Interactor (?)Score for PLK1-Interactor (?)
PSMA5 PSMA5: Proteasome subunit alpha type-5 1.02E4 0.878
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 3.41E3 0.878
PSMA4 PSMA4, PSC9: Proteasome subunit alpha type-4 2.07E3 0.195
PSMA7 PSMA7: Proteasome subunit alpha type-7 1.64E3 0.195
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 1.59E3 0.878
PSMB2 PSMB2: Proteasome subunit beta type-2 691.00 0.195
PSMB1 PSMB1, PSC5: Proteasome subunit beta type-1 precursor 691.00 0.195
PSMB6 PSMB6, LMPY: Proteasome subunit beta type-6 precursor 323.00 0.195
PSMA8 PSMA8, PSMA7L: Proteasome subunit alpha type-7-like 319.00 0.195
PSMB3 PSMB3: Proteasome subunit beta type-3 195.00 0.195
PSMA6 PSMA6, PROS27: Proteasome subunit alpha type-6 195.00 0.195
PSMB9 PSMB9, LMP2, RING12: Proteasome subunit beta type-9 precursor 31.70 0.195
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 10.50 0.025
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 5.97 0.044
NUP98 N/A 3.39 0.025
FNBP1 N/A 3.35 0.075
PSMA1 PSMA1, PROS30, PSC2: Proteasome subunit alpha type-1 2.91 0.217
CSNK2A1 CSNK2A1: CSNK2A1 protein 1.62 0.075
NULL RcPSMB3 (Fragment) 1.37 0.0258
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.852 0.083
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.763 0.075
CDK7 CDK7, MO15: Cell division protein kinase 7 0.763 0.075
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.763 0.075
CDK4 CDK4: Cell division protein kinase 4 0.763 0.075
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.704 0.025
CTRL PSMB10, MECL1: Proteasome subunit beta type-10 precursor 0.666 0.217
PSMB4 PSMB4: Proteasome subunit beta type-4 precursor 0.617 0.617
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.515 0.083
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.461 21.10
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.461 0.075
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.461 0.075
CDK2 CDK2: Cell division protein kinase 2 0.461 3.97
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.423 0.025
ROCK1 ROCK1: Rho-associated protein kinase 1 0.416 0.165
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.098
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.372 0.075
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.372 0.075
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.372 0.075
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.372 0.098
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.372 0.075
RPS6KB1 N/A 0.372 0.075
WEE1 WEE1: Wee1-like protein kinase 0.372 0.075
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.372 0.075
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.372 0.075
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.372 0.075
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.372 0.075
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.307 0.083
STK16 N/A 0.307 0.083
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.304 0.075
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.276 0.036
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.275 0.148
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.148
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.275 0.044
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.148
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.275 0.075
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.275 0.075
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.275 0.075
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.275 0.025
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.275 0.075
PSMB5 PSMB5, LMPX: Proteasome subunit beta type-5 precursor 0.265 0.217
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.251 0.083
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.233 0.098
CSK CSK: Tyrosine-protein kinase CSK 0.233 0.098
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.225 0.044
STK10 STK10: Uncharacterized protein STK10 0.225 0.075
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.225 0.075
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.225 0.075
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.225 0.075
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.225 0.075
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.225 0.075
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.225 0.075
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.225 0.098
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.191 0.083
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.191 0.083
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.191 0.083
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.191 0.083
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.191 0.083
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.191 0.083
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.188 0.098
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.171 0.075
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.171 0.075
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.171 0.075
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.171 0.075
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.166 0.083
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.165 0.083
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.083
MAPK15 N/A 0.165 0.083
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.165 0.049
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.165 0.049
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.083
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.165 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.165 0.083
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.165 0.083
MAPKAPK5 N/A 0.165 0.083
SET SET: Protein SET 0.157 0.028
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.157 0.165
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.155 0.109
PRKAA1 N/A 0.152 0.083
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.152 0.083
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.152 0.083
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.152 0.083
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.148 0.075
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.148 0.075
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.075
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.148 0.075
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.148 0.075
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.148 0.075
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.148 0.075
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.148 0.075
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.148 0.075
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.148 0.075
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.075
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.148 0.075
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.148 0.075
CDC2 CDC2: Cell division control protein 2 homolog 0.148 0.075
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.148 0.044
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.028
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.144 0.049
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.144 0.028
ABCF1 N/A 0.144 0.028
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.141 6.64
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.141 0.025
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.141 0.025
SSB SSB: Lupus La protein 0.141 0.025
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.141 0.075
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.141 1.33
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.141 0.025
NPM1 NPM1, NPM: Nucleophosmin 0.141 0.075
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.141 0.025
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.141 6.64
SYK SYK: Tyrosine-protein kinase SYK 0.139 0.098
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.136 0.075
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.136 0.075
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.136 0.075
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.136 0.044
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.136 0.075
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.136 0.075
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.136 0.075
CDK6 CDK6: Cell division protein kinase 6 0.136 0.075
CDK5 CDK5: Cell division protein kinase 5 0.136 0.075
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.129 0.025
CTPS CTPS: CTP synthase 1 0.129 0.044
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.129 0.044
VCP VCP: Transitional endoplasmic reticulum ATPase 0.129 0.044
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.129 0.044
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.129 0.025
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.129 0.044
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.129 0.025
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.129 0.044
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.129 0.075
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.129 0.044
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.129 0.025
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.127 0.109
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.126 0.075
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.123 0.083
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.123 0.083
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.114 0.030
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.114 0.098
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.075
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.114 0.025
LYN LYN: Tyrosine-protein kinase Lyn 0.114 0.098
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.111 0.075
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.111 0.075
DYRK3 N/A 0.111 0.075
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.111 0.044
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.111 0.044
DAPK2 DAPK2: Death-associated protein kinase 2 0.109 0.083
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.109 0.083
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.109 0.109
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.103 0.083
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.099 0.075
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.099 0.075
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.099 0.075
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.099 0.075
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.099 0.075
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.099 0.098
CDKL5 N/A 0.098 0.083
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.098 0.075
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.098 0.030
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.098 0.075
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.097 0.044
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.097 0.075
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.097 0.075
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.097 35.90
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.097 0.075
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.097 0.075
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.093 0.075
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.090 0.030
MYO3A MYO3A: Myosin IIIA 0.088 0.075
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.088 0.098
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.088 0.075
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.088 0.148
API5 N/A 0.087 0.028
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.087 0.028
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.087 0.04
ESPL1 N/A 0.087 0.028
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.086 0.098
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.086 0.098
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.086 0.098
JAK1 0.086 0.098
LIMK2 LIMK2: LIM domain kinase 2 0.085 0.049
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.083 0.109
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.078 0.075
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.078 0.075
CRKL CRKL: Crk-like protein 0.078 0.098
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.078 0.044
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.078 0.148
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.078 0.025
RPS10 RPS10: 40S ribosomal protein S10 0.078 0.044
CD2AP CD2AP: CD2-associated protein 0.078 0.044
NRAS NRAS, HRAS1: GTPase NRas precursor 0.078 0.036
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.078 0.036
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.083
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.077 0.109
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.077 0.109
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.044
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.075 0.098
EEF2K EEF2K: Elongation factor 2 kinase 0.075 0.148
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.075 0.098
DNMT1 DNMT1, AIM, DNMT: DNA 0.074 0.028
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.074 0.028
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.074 0.028
TCOF1 N/A 0.074 0.028
DDX21 DDX21: Nucleolar RNA helicase 2 0.074 0.028
NBN NBN, NBS, NBS1, P95: Nibrin 0.074 0.052
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.074 0.028
GNB2L1 Lung cancer oncogene 7 0.074 0.028
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.074 0.028
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.073 0.030
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.070 0.04
SRPR SRPR: Uncharacterized protein SRPR 0.070 0.049
UBAP2 N/A 0.070 0.028
TRRAP N/A 0.070 0.028
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.070 0.109
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.028
CHUK N/A 0.070 0.028
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.069 0.098
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.069 0.098
ATM ATM: Serine-protein kinase ATM 0.069 0.075
HCK N/A 0.069 0.098
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.069 0.075
SOS1 SOS1: Son of sevenless homolog 1 0.067 0.148
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.066 0.025
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.066 0.025
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.066 0.075
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.066 0.025
MCM3 MCM3: DNA replication licensing factor MCM3 0.066 0.148
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.066 0.025
TIAL1 TIAL1: Nucleolysin TIAR 0.066 0.025
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.066 0.025
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.066 0.025
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.066 0.025
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.066 0.025
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.066 0.025
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.066 6.64
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.066 0.025
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.066 0.137
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.066 0.025
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.066 0.025
CBX3 CBX3: Chromobox protein homolog 3 0.066 0.025
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.066 0.025
TP53 TP53, P53: Cellular tumor antigen p53 0.066 0.025
HDAC2 HDAC2: Histone deacetylase 2 0.066 0.025
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.066 6.64
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.066 0.025
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.066 0.025
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.064 0.083
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.063 0.075
HSP90AA1 Hsp89-alpha-delta-N 0.063 0.044
SEC24B SEC24B: Protein transport protein Sec24B 0.063 0.044
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.063 0.098
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.063 0.025
MDN1 MDN1, KIAA0301: Midasin 0.063 0.075
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.063 0.044
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.063 0.036
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.063 0.025
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.063 0.025
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.063 0.098
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.063 0.075
SAPS3 N/A 0.063 0.025
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.063 0.044
COPA COPA: Coatomer subunit alpha 0.063 0.025
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.063 0.098
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.062 0.028
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.058 0.075
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.058 0.075
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.058 0.075
MAP2K5 N/A 0.056 0.109
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.056 0.083
BMX N/A 0.055 0.109
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.052 0.165
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.052 0.028
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.028
CIITA CIITA, MHC2TA: MHC class II transactivator 0.052 0.049
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.052 0.049
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.052 0.083
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.052 0.083
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.052 0.049
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.051 0.083
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.051 0.030
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.050 0.075
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.050 0.075
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.050 0.075
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.049 0.098
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.049 0.098
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.049 0.044
PLD1 PLD1: Phospholipase D1 0.046 0.098
KIAA1012 KIAA1012: Protein TRS85 homolog 0.046 0.025
CXorf9 N/A 0.046 0.075
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.046 0.036
THOC1 THOC1, HPR1: THO complex subunit 1 0.046 0.044
VAV1 VAV1, VAV: Proto-oncogene vav 0.046 0.098
MSN MSN: Moesin 0.046 0.098
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.046 0.025
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.046 0.025
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.046 0.044
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.046 0.044
DOK1 DOK1: Docking protein 1 0.046 0.148
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.046 0.025
WASPIP N/A 0.046 0.044
GSK3B N/A 0.046 0.025
STMN1 STMN1, LAP18, OP18: Stathmin 0.046 0.098
STAT6 STAT6: Signal transducer and activator of transcription 6 0.046 0.098
AIP AIP, XAP2: AH receptor-interacting protein 0.046 0.025
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.025
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.046 0.098
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.046 6.64
KLHDC4 N/A 0.046 0.025
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.025
CENPA CENPA: Histone H3-like centromeric protein A 0.0446 0.028
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.0446 0.028
MATR3 MATR3, KIAA0723: Matrin-3 0.0446 0.028
PTMA N/A 0.0446 0.052
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.0446 0.165
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.0446 0.083
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.0446 0.028
FADD FADD, MORT1: Protein FADD 0.0446 0.034
IFI16 N/A 0.0446 0.028
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.0446 0.028
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.0446 0.083
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.0446 0.028
WDR1 N/A 0.0446 0.028
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0446 0.028
MKI67 MKI67: Antigen KI-67 0.0446 0.052
RB1 RB1: Retinoblastoma-associated protein 0.0446 0.083
TOP2B N/A 0.0446 0.028
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.0425 0.04
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0425 0.049
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.028
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.165
VASP VASP: Vasodilator-stimulated phosphoprotein 0.0425 0.109
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.040 6.64
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.040 0.025
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.040 0.148
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.040 0.075
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.040 0.025
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.040 0.025
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.040 0.025
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.040 0.075
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.040 0.025
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.040 0.025
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.040 0.025
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.040 6.64
PCNA PCNA: Proliferating cell nuclear antigen 0.040 0.025
YY1 YY1: Transcriptional repressor protein YY1 0.040 0.025
PPP1R8 N/A 0.040 0.047
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.040 0.025
HDAC3 HDAC3: Histone deacetylase 3 0.040 0.025
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.040 0.025
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.040 0.025
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.040 0.075
NUP153 N/A 0.040 0.025
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.040 0.025
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.040 0.025
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.040 0.025
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.040 0.025
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.040 0.030
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.040 0.075
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.040 0.025
CDC20 CDC20: Cell division cycle protein 20 homolog 0.040 0.075
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.040 0.148
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.040 0.025
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.040 0.025
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.040 0.025
KIF11 N/A 0.040 0.025
LIG1 LIG1: DNA ligase 1 0.040 0.025
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.040 0.025
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.040 0.025
MTA1 MTA1: Metastasis-associated protein MTA1 0.040 0.025
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.040 0.025
RBM7 0.040 0.025
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.040 0.148
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.040 0.025
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.040 0.025
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.040 0.075
POLA2 POLA2: DNA polymerase subunit alpha B 0.040 0.025
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.040 0.025
CCNB1 Cyclin B1 0.040 0.148
H2AFX H2AFX, H2AX: Histone H2A.x 0.040 0.025
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.040 0.025
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.040 0.025
APS SH2B2, APS: SH2B adapter protein 2 0.038 0.098
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.038 0.025
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.038 0.025
SYMPK SYMPK, SPK: Symplekin 0.038 0.025
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.038 0.044
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.038 0.098
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.038 0.036
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.038 0.025
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.038 0.025
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.038 0.025
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.038 0.025
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.038 0.098
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.038 0.044
FKBP4 FKBP4: FK506-binding protein 4 0.038 0.025
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.038 0.148
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.038 0.025
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.038 0.025
VIL2 N/A 0.038 0.098
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.037 0.075
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.037 0.030
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.036 0.028
GTF2F2 N/A 0.036 0.028
RBM14 RBM14, SIP: RNA-binding protein 14 0.036 0.028
KIF23 N/A 0.036 0.028
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.036 0.028
ELF1 ELF1: ETS-related transcription factor Elf-1 0.036 0.083
ZNF267 ZNF267: Zinc finger protein 267 0.036 0.028
PLEK PLEK, P47: Pleckstrin 0.036 0.165
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.036 0.028
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.036 0.028
NCOA3 N/A 0.036 0.028
ARFGAP1 N/A 0.036 0.083
KIAA0853 N/A 0.036 0.028
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.036 0.028
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.0333 0.165
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.033 0.075
SNRPA SNRPA: U1 small nuclear ribonucleoprotein A 0.033 1.16
KIT KIT: Mast/stem cell growth factor receptor precursor 0.033 0.030
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.033 0.030
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.033 0.030
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.033 0.030
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.033 0.075
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.032 0.109
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.049
MARK2 N/A 0.032 0.028
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.032 0.028
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.032 0.165
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.032 0.049
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.028
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.032 0.028
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.032 0.109
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.032 0.083
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.032 0.028
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.032 0.025
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.032 0.025
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.032 0.025
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.032 0.025
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.032 0.025
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.032 0.025
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.032 0.025
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.032 0.025
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.032 0.075
WBSCR20A N/A 0.032 0.025
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.032 0.025
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.032 0.025
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.032 6.64
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.032 0.025
CUL5 CUL5, VACM1: Cullin-5 0.032 0.025
CORO1C CORO1C, CRNN4: Coronin-1C 0.032 0.025
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.032 0.025
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.032 0.025
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.032 0.025
UNG N/A 0.032 0.025
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.032 0.025
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.032 0.148
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.032 0.025
CUL4B N/A 0.032 0.025
MYBL2 MYBL2, BMYB: Myb-related protein B 0.032 0.025
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.032 0.025
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.032 0.025
SRF SRF: Serum response factor 0.032 0.025
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.032 0.148
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.030 0.083
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.030 0.025
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.030 0.025
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.0296 0.075
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.029 0.030
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.029 0.030
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.030
PLD2 PLD2: Phospholipase D2 0.029 0.098
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.029 0.025
RDX RDX: Radixin 0.029 0.098
BRPF1 BRPF1, BR140: Peregrin 0.029 0.025
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.029 0.098
GMIP GMIP: GEM-interacting protein 0.029 0.044
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.029 0.075
CSDA CSDA, DBPA: DNA-binding protein A 0.029 0.025
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.029 0.148
NCK2 NCK2: Cytoplasmic protein NCK2 0.029 0.098
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.029 0.098
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.029 0.025
PI4KII PI4K2A: Phosphatidylinositol 4-kinase type 2-alpha 0.029 0.025
PSCD4 PSCD4, CYT4: Cytohesin-4 0.029 0.098
STAM2 STAM2: Signal transducing adapter molecule 2 0.029 0.044
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.029 0.098
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.029 0.025
PSMB8 PSMB8, LMP7, RING10, Y2: Proteasome subunit beta type-8 precursor 0.0288 0.0288
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.028 0.109
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.028 0.049
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.028 0.109
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.028 0.109
CASP8 CASP8, MCH5: Caspase-8 precursor 0.028 0.049
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.028 0.04
PHLDB2 N/A 0.028 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.028 0.049
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
LNK SH2B3, LNK: SH2B adapter protein 3 0.028 0.109
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.028 0.049
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
DNM3 DNM3: Uncharacterized protein DNM3 0.028 0.109
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.028 0.109
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.028 0.049
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.028 0.109
AMPH AMPH, AMPH1: Amphiphysin 0.028 0.049
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
PSCD2 N/A 0.028 0.109
NF2 NF2, SCH: Merlin 0.028 0.165
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.027 0.028
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.027 0.034
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.027 0.028
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.027 0.028
HIVEP1 N/A 0.027 0.028
RBM6 RBM6, DEF3: RNA-binding protein 6 0.027 0.028
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.027 0.028
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.027 0.028
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.027 0.028
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.027 0.083
IRF3 IRF3: Interferon regulatory factor 3 0.027 0.028
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.027 0.028
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.027 0.028
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.027 0.083
CD44 N/A 0.027 0.034
XRCC1 XRCC1: DNA-repair protein XRCC1 0.027 0.028
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.027 0.028
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.026 0.030
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.026 0.030
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.028
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.028
IRS1 IRS1: Insulin receptor substrate 1 0.026 0.165
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.026 0.109
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.026 0.109
GRLF1 N/A 0.026 0.083
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.026 0.109
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.025 0.083
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.025 0.098
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.025 0.098
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
CAMK2A N/A 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.075
TSC2 TSC2, TSC4: Tuberin 0.025 0.044
BCOR N/A 0.025 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.025 0.098
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.025 0.044
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.025 0.044
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.148
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.025 0.098
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.025 0.098
GRK6 N/A 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
PRKCB1 N/A 0.025 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.025 0.036
ARHGEF7 N/A 0.025 0.098
MAP2K3 N/A 0.025 0.025
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.025 0.044
CAMKK1 N/A 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.025 0.044
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.025 0.098
STAT3 0.025 0.098
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.025 0.044
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.148
GIT2 N/A 0.025 0.075
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
RAB5B RAB5B: Ras-related protein Rab-5B 0.025 0.036
ELMO1 N/A 0.025 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.025 0.044
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.025 0.098
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.025 0.044
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 71.20
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
0.572
Total Score 1.58E4