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Evidence of Interaction Between PDCD6IP and CHMP4C

The interaction score between PDCD6IP and CHMP4C is 32.80.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

N/A
Orthology
OrganismPDCD6IP OrthologueCHMP4C OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00735201 0.166 IPI00025974 0.157
human IPI00735201 0.166 IPI00023068 0.279
bakers yeast YOR275C 1 YLR025W 0.279
  • Y2H
  • Other

Get References From PubMed

worm P34552 1 Q18886 0.157
fly Q9VB05 1 Q8T0Q4 0.246

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.119
Domains No domains were used in calculating likelihood of interaction 3.00E-3
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: PDCD6IP

LocalisationReference
Cytosol HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: CHMP4C

LocalisationReference
Cytosol HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PDCD6IP and CHMP4C that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PDCD6IP andCHMP4C. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PDCD6IP has 52 interactors and CHMP4C has 25 interactors of which there are 5 common interactors.

Common InteractorName of Common InteractorScore for PDCD6IP-Interactor (?)Score for CHMP4C-Interactor (?)
CHMP4A N/A 3.68 319.00
VPS4B VPS4B, SKD1, VPS42: Vacuolar protein sorting-associating protein 4B 1.84 169.00
VPS4A VPS4A, VPS4: Vacuolar protein sorting-associating protein 4A 0.221 3.58
CHMP4B CHMP4B, C20orf178, SHAX1: Charged multivesicular body protein 4b 0.143 319.00
LOC283683 N/A 0.119 0.064
0.572
Total Score 32.80