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Evidence of Interaction Between PDGFRB and FGR

The interaction score between PDGFRB and FGR is 6.45E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between PDGFRB and FGR = -0.21

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.65E-3
Orthology
OrganismPDGFRB OrthologueFGR OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00022296 0.132 IPI00013864 0.061
  • Other
  • InVitro
  • InVivo

Get References From PubMed
human IPI00027721 0.325 IPI00013864 0.061
human IPI00018335 1 IPI00013864 0.061
human IPI00021396 1 IPI00013864 0.061
human IPI00293565 0.322 IPI00013864 0.061
human IPI00005722 0.081 IPI00013864 0.061
worm P34892 0.084 Q9BKW3 0.411
worm O76698 1 Q9BKW3 0.411
worm Q21038 1 Q9BKW3 0.411
worm Q21041 1 Q9BKW3 0.411

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 1.07
Domains Domains present in PDGFRB and FGR:
Domains in PDGFRBDomains in FGR
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR001452 SH3
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in PDGFRB and FGR are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR008266 Tyrosine protein kinase, active site IPR001452 SH3 164.706
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR001245 Tyrosine protein kinase IPR001452 SH3 100.857
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR003599 Immunoglobulin subtype IPR000980 SH2 motif 66.4833
IPR003598 Immunoglobulin C-2 type IPR000980 SH2 motif 64.7072
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR013151 Immunoglobulin. IPR000980 SH2 motif 36.9251
IPR001824 Receptor tyrosine kinase, class III IPR001452 SH3 32.2626
IPR000719 Protein kinase IPR000719 Protein kinase 30.6895
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR011009 Protein kinase-like IPR011009 Protein kinase-like 26.2215
IPR003598 Immunoglobulin C-2 type IPR001452 SH3 26.0449
IPR003599 Immunoglobulin subtype IPR001452 SH3 22.2905
IPR011009 Protein kinase-like IPR001452 SH3 20.4416
IPR007110 Immunoglobulin-like IPR001452 SH3 20.3228
IPR007110 Immunoglobulin-like IPR011009 Protein kinase-like 16.6203
IPR003598 Immunoglobulin C-2 type IPR008266 Tyrosine protein kinase, active site 15.3939
IPR013151 Immunoglobulin. IPR001452 SH3 14.5395
IPR007110 Immunoglobulin-like IPR000719 Protein kinase 11.3335
IPR008266 Tyrosine protein kinase, active site IPR008266 Tyrosine protein kinase, active site 9.50479
IPR003599 Immunoglobulin subtype IPR011009 Protein kinase-like 8.86948
IPR003599 Immunoglobulin subtype IPR008266 Tyrosine protein kinase, active site 8.71812
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001452 SH3 8.64336
IPR007110 Immunoglobulin-like IPR008266 Tyrosine protein kinase, active site 8.13215
IPR000719 Protein kinase IPR008266 Tyrosine protein kinase, active site 6.98997
IPR003598 Immunoglobulin C-2 type IPR001245 Tyrosine protein kinase 4.5123
IPR001824 Receptor tyrosine kinase, class III IPR008266 Tyrosine protein kinase, active site 4.49385
IPR013151 Immunoglobulin. IPR008266 Tyrosine protein kinase, active site 4.11154
IPR003599 Immunoglobulin subtype IPR000719 Protein kinase 3.60485
IPR000719 Protein kinase IPR011009 Protein kinase-like 2.94434
IPR013151 Immunoglobulin. IPR011009 Protein kinase-like 2.74789
IPR000719 Protein kinase IPR001245 Tyrosine protein kinase 2.31134
IPR013151 Immunoglobulin. IPR000719 Protein kinase 1.81655
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR008266 Tyrosine protein kinase, active site 1.70807
IPR001824 Receptor tyrosine kinase, class III IPR001245 Tyrosine protein kinase 1.57698
IPR003598 Immunoglobulin C-2 type IPR011009 Protein kinase-like 1.32999
IPR003599 Immunoglobulin subtype IPR001245 Tyrosine protein kinase 1.01254
IPR001245 Tyrosine protein kinase IPR008266 Tyrosine protein kinase, active site 0.959759
IPR013151 Immunoglobulin. IPR001245 Tyrosine protein kinase 0.63318
IPR007110 Immunoglobulin-like IPR001245 Tyrosine protein kinase 0.479454
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001245 Tyrosine protein kinase 0.339832
IPR001245 Tyrosine protein kinase IPR011009 Protein kinase-like 0.178275
IPR003598 Immunoglobulin C-2 type IPR000719 Protein kinase 0.142823
IPR001824 Receptor tyrosine kinase, class III IPR011009 Protein kinase-like 0.099805
IPR001245 Tyrosine protein kinase IPR001245 Tyrosine protein kinase 0.0451828
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR011009 Protein kinase-like 0.00926039
IPR008266 Tyrosine protein kinase, active site IPR011009 Protein kinase-like 0.00724826
IPR001824 Receptor tyrosine kinase, class III IPR000719 Protein kinase 0.000102653
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000719 Protein kinase 0.0000462868

The background colour of the table refers to:

  • Blue Domain is only present in PDGFRB
  • Yellow Domain is only present in FGR
  • Green Domain is present in both PDGFRB and FGR

 0.980
Post-translational Modifications

Protein: PDGFRB

PTMResidueReference
Dephosphorylation 562 PubMed, HPRD
Dephosphorylation 579 PubMed, HPRD
Dephosphorylation 740 PubMed, HPRD
Dephosphorylation 751 PubMed, HPRD
Dephosphorylation 771 PubMed, HPRD
Dephosphorylation 857 PubMed, HPRD
Dephosphorylation 1009 PubMed, HPRD
Dephosphorylation 1021 PubMed, HPRD
Phosphorylation 579 PubMed, HPRD
Phosphorylation 581 PubMed, HPRD
Phosphorylation 716 PubMed, HPRD
Phosphorylation 740 PubMed, HPRD
Phosphorylation 751 PubMed, HPRD
Phosphorylation 763 PubMed, HPRD
Phosphorylation 771 PubMed, HPRD
Phosphorylation 775 PubMed, HPRD
Phosphorylation 857 PubMed, HPRD
Phosphorylation 1009 PubMed, HPRD
Phosphorylation 1021 PubMed, HPRD
Phosphotyrosine 751 PubMed, HPRD
Phosphotyrosine 857 PubMed, HPRD

Protein: FGR

PTMResidueReference
Phosphorylation 412 PubMed, HPRD
Phosphorylation 523 PubMed, HPRD
Localisation

Protein: PDGFRB

LocalisationReference
Plasma membrane HPRD

Protein: FGR

LocalisationReference
Cytoplasm HPRD
Transitive Score

The common interactors between PDGFRB and FGR that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PDGFRB andFGR. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PDGFRB has 1323 interactors and FGR has 1706 interactors of which there are 874 common interactors.

Common InteractorName of Common InteractorScore for PDGFRB-Interactor (?)Score for FGR-Interactor (?)
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 1.01E3 1.17
NCK2 NCK2: Cytoplasmic protein NCK2 600.00 1.35
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 600.00 1.78
CRKL CRKL: Crk-like protein 536.00 1.35
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 532.00 0.586
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 422.00 1.17
STAT5B STAT5B: Signal transducer and activator of transcription 5B 372.00 1.62
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 315.00 0.694
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 281.00 1.07
VAV1 VAV1, VAV: Proto-oncogene vav 281.00 6.03
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 277.00 0.874
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 277.00 1.07
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 265.00 0.553
STAT6 STAT6: Signal transducer and activator of transcription 6 250.00 12.80
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 250.00 2.17
HCK N/A 250.00 12.80
JAK2 JAK2: Tyrosine-protein kinase JAK2 250.00 6.03
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 232.00 0.878
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 183.00 0.586
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 147.00 67.50
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 137.00 0.655
GRAP GRAP: GRB2-related adapter protein 133.00 0.218
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 112.00 2.73
KIT KIT: Mast/stem cell growth factor receptor precursor 112.00 0.577
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 84.00 0.097
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 82.20 0.577
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 74.00 0.781
JUP JUP, CTNNG, DP3: Junction plakoglobin 37.90 0.049
SHC2 N/A 29.70 12.40
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 19.20 0.040
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 15.80 0.088
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 12.50 0.097
PRKCG PRKCG, PKCG: Protein kinase C gamma type 12.50 0.097
SOCS7 SOCS7, NAP4, SOCS6: Suppressor of cytokine signaling 7 12.40 0.0258
SHC4 SHC-transforming protein 4 2.58 1.07
LOC392481 N/A 2.58 1.07
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 1.13 0.975
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 1.30
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 1.30
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 1.30
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 1.30
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 1.30
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.916 0.139
BMX N/A 0.902 0.859
STAT3 0.878 1.17
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 0.694
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 1.50
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.731 1.50
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.731 0.775
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 0.770
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.654 6.73
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.654 4.07
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.654 4.07
SYK SYK: Tyrosine-protein kinase SYK 0.654 4.07
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.859
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 1.50
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.644 1.20
JAK1 0.644 3.28
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.617
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.617
CRK CRK: Proto-oncogene C-crk 0.617 0.617
GRB10 N/A 0.617 0.617
APS SH2B2, APS: SH2B adapter protein 2 0.586 1.78
LYN LYN: Tyrosine-protein kinase Lyn 0.586 12.80
CSK CSK: Tyrosine-protein kinase CSK 0.586 3.64
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.581 1.20
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 0.859
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.581 1.20
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.581 6.73
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.553
RIN1 RIN1: Ras and Rab interactor 1 0.520 1.07
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.520 1.78
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.372 0.058
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.360 2.46
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.644
STAT2 STAT2: Signal transducer and activator of transcription 2 0.320 1.13
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.318 1.33
STAT4 STAT4: Signal transducer and activator of transcription 4 0.286 0.808
TNC TNC, HXB: Tenascin precursor 0.275 0.058
CD63 CD63, MLA1, TSPAN30: CD63 antigen 0.275 0.027
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.275 0.065
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.251 0.581
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.251 0.0727
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.251 0.0727
VWF VWF, F8VWF: von Willebrand factor precursor 0.245 0.037
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.245 0.088
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.233 0.064
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.225 0.064
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.265
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.265
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.265
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.265
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.202 0.041
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.202 0.041
CNN3 CNN3: Calponin-3 0.202 0.078
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.202 0.041
SOCS5 SOCS5, CIS6, CISH5, CISH6, KIAA0671: Suppressor of cytokine signaling 5 0.200 0.157
GHR GHR: Growth hormone receptor precursor 0.191 0.072
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.191 0.065
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.0727
SPARC SPARC, ON: SPARC precursor 0.181 0.037
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.181 0.037
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.181 0.088
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.181 0.037
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.181 0.037
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.181 0.088
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.171 0.099
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.171 0.577
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.166 0.041
KIR3DL1 N/A 0.165 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
FN1 N/A 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.980
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.098
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.098
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
GRB14 GRB14: Growth factor receptor-bound protein 14 0.162 0.176
GRB7 GRB7: Growth factor receptor-bound protein 7 0.162 0.157
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.152 0.581
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.152 0.065
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.152 0.072
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.152 0.072
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.152 0.100
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.152 0.072
DAB2 DAB2, DOC2: Disabled homolog 2 0.148 0.097
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.878
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.878
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.098
BSG N/A 0.148 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.878
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 0.098
ATRN N/A 0.148 0.044
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.098
SOCS2 SOCS2, CIS2, SSI2, STATI2: Suppressor of cytokine signaling 2 0.145 0.156
SHB SHB: SH2 domain-containing adapter protein B 0.145 0.158
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.143 0.305
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.136 0.520
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.136 0.577
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.136 0.655
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.136 0.577
INSR INSR: Insulin receptor precursor 0.136 0.577
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.136 0.520
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.129 0.305
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.129 0.402
FYN N/A 0.129 0.666
VAV3 VAV3: Protein vav-3 0.128 0.360
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.127 0.029
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.126 0.152
IRS1 IRS1: Insulin receptor substrate 1 0.126 0.109
CTTN CTTN, EMS1: Src substrate cortactin 0.126 2.23
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.125 0.046
EGF EGF: Pro-epidermal growth factor precursor 0.123 0.072
PRLR PRLR: Prolactin receptor precursor 0.123 0.065
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.123 0.072
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.123 0.072
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.081
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.123 0.126
MET MET: Hepatocyte growth factor receptor precursor 0.123 0.654
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.123 0.072
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.081
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.065
PVR PVR, PVS: Poliovirus receptor precursor 0.123 0.065
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.123 0.126
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.166
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.0727
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.123 0.081
F3 F3: Tissue factor precursor 0.123 0.065
CHN1 CHN1, ARHGAP2, CHN: N-chimaerin 0.115 0.141
RIN3 N/A 0.115 2.60
CHN2 CHN2, ARHGAP3, BCH: Beta-chimaerin 0.115 0.156
FKBP9 FKBP9, FKBP60, FKBP63: FK506-binding protein 9 precursor 0.114 0.037
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.114 0.029
CHP CHP: Calcium-binding protein p22 0.113 0.225
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.113 0.088
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.112 0.049
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.111 0.520
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.111 0.041
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.111 0.586
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.111 0.065
NEO1 NEO1, NGN: Neogenin precursor 0.111 0.052
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.111 0.520
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.110 0.274
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.110 0.274
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.110 0.561
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.110 0.100
ITGAE ITGAE: Integrin alpha-E precursor 0.110 0.036
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.110 0.340
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.110 0.036
SORL1 SORL1: Sortilin-related receptor precursor 0.110 0.245
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.110 0.074
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.110 0.561
LILRB1 N/A 0.110 1.19
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.110 0.081
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.109 0.165
NF2 NF2, SCH: Merlin 0.109 0.165
PPEF1 N/A 0.109 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.165
PSCD2 N/A 0.109 0.165
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
CNN2 CNN2: Calponin-2 0.109 0.148
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.081
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.109 0.072
ITGB4 N/A 0.109 0.065
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.109 0.126
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.109 0.065
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.109 0.100
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.109 0.654
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.100
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.109 0.274
EPOR EPOR: Erythropoietin receptor precursor 0.109 0.072
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.109 0.072
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.072
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.166
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.109 0.274
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.561
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.109 0.0727
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.109 0.081
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.109 0.274
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.109 0.072
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.101 0.041
CP CP: Ceruloplasmin precursor 0.100 0.041
F8 F8, F8C: Coagulation factor VIII precursor 0.100 0.046
INHA INHA: Inhibin alpha chain precursor 0.100 0.041
TNNC1 TNNC1, TNNC: Troponin C, slow skeletal and cardiac muscles 0.100 0.037
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.100 0.045
S100A3 S100A3, S100E: Protein S100-A3 0.100 0.098
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.100 0.045
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.099 0.245
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.098 0.152
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.098 0.126
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.081
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.098 0.561
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.126
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.098 0.100
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.100
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.098 0.126
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.081
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.098 0.157
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.098 0.340
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.098 0.561
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.098 0.202
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.098 0.274
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.098 0.561
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.098 0.081
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.098 0.561
PTPRZ1 N/A 0.098 0.065
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.098 0.274
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.098 0.561
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.148
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.098 0.030
ELMO1 N/A 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.148
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.098 0.030
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.148
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.098 0.025
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.148
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.148
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.098 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
SNX3 N/A 0.098 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
ARHGEF7 N/A 0.098 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.148
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.148
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.098 0.030
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.577
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.577
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.097 0.520
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.064
DCC DCC: Netrin receptor DCC precursor 0.097 0.064
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.096 0.075
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.096 0.029
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.049
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.090 5.88
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.099
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.090 0.099
MYL3 MYL3: Myosin light polypeptide 3 0.090 0.097
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.111
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.090 0.041
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.088 0.064
CD82 CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen 0.088 0.054
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.088 0.655
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.088 3.22
ITGB7 ITGB7: Integrin beta-7 precursor 0.088 0.0818
CRLF3 N/A 0.088 0.340
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.086 0.029
CAV1 CAV1, CAV: Caveolin-1 0.086 0.0273
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
EDA N/A 0.083 0.049
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.083 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.049
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.083 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 1.20
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.081 0.123
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.081 0.041
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.081 0.307
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.081 0.046
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.081 0.191
CGA CGA: Glycoprotein hormones alpha chain precursor 0.081 0.045
NDP NDP: Norrin precursor 0.081 0.046
S100A7 S100A7, PSOR1: Protein S100-A7 0.081 0.109
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.081 0.098
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.063
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.081 0.045
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.081 0.515
SPTAN1 N/A 0.081 0.110
CAV2 CAV2: Caveolin-2 0.0782 0.030
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0782 0.034
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.077 0.124
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.098
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.044
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.073 0.097
RASA3 RASA3: Ras GTPase-activating protein 3 0.073 0.136
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.073 0.097
PLD1 PLD1: Phospholipase D1 0.073 0.111
RDX RDX: Radixin 0.073 0.088
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.073 0.099
SORBS3 SORBS3, SCAM1: Vinexin 0.073 0.097
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.073 0.097
PLD2 PLD2: Phospholipase D2 0.073 0.111
TTN N/A 0.073 0.097
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.073 0.372
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.073 0.088
SH3BP5 N/A 0.073 0.225
DLG2 DLG2: Disks large homolog 2 0.073 0.041
TST TST: Thiosulfate sulfurtransferase 0.073 0.097
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.073 0.099
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.073 0.097
TLN2 TLN2: Uncharacterized protein TLN2 0.073 0.078
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.0727 1.81
ROCK1 ROCK1: Rho-associated protein kinase 1 0.0727 0.416
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.0727 0.171
IPO7 IPO7: Uncharacterized protein IPO7 0.0727 0.026
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0727 0.852
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.109
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.072 0.063
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.072 0.152
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.072 0.063
S100B S100B: Protein S100-B 0.072 0.098
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.416
IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 0.072 0.063
TSHB TSHB: Thyrotropin subunit beta precursor 0.072 0.045
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.109
GRLF1 N/A 0.072 0.109
FSHB FSHB: Follitropin subunit beta precursor 0.072 0.045
F5 F5: Coagulation factor V precursor 0.072 0.105
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.072 0.140
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.072 0.098
IRS2 IRS2: Insulin receptor substrate 2 0.072 0.515
LHB LHB: Lutropin subunit beta precursor 0.072 0.045
GAB1 GAB1: GRB2-associated-binding protein 1 0.072 0.152
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.072 0.045
NSBP1 NSBP1: Nucleosome-binding protein 1 0.0688 0.109
CETN1 CETN1, CEN1, CETN: Centrin-1 0.0688 0.109
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.065 0.763
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.065 86.60
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.065 0.372
LCP1 LCP1, PLS2: Plastin-2 0.065 0.763
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.065 0.763
CXorf9 N/A 0.065 0.763
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.065 0.372
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.065 0.111
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.065 0.763
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.065 0.461
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.065 86.60
GMIP GMIP: GEM-interacting protein 0.065 1.62
PSCD4 PSCD4, CYT4: Cytohesin-4 0.065 0.461
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.065 0.372
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.065 0.171
CD2AP CD2AP: CD2-associated protein 0.065 0.171
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.065 0.225
FNBP1 N/A 0.065 10.60
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.065 0.098
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.191
GAB2 N/A 0.065 0.307
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.065 0.852
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.065 0.416
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.065 0.098
CSPG2 N/A 0.065 0.354
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.065 0.109
VASP VASP: Vasodilator-stimulated phosphoprotein 0.065 0.515
SNCB SNCB: Beta-synuclein 0.065 0.098
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.065 0.041
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.065 0.174
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.065 0.109
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.065 0.123
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.064 0.046
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.064 0.037
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.171
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.064 0.275
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.064 0.171
TLN1 TLN1: Uncharacterized protein TLN1 0.064 0.372
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.064 0.099
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.041
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.064 0.111
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.361
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.064 0.037
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.064 0.225
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.064 0.099
FGF9 FGF9: Glia-activating factor precursor 0.064 0.041
VIL2 N/A 0.064 0.171
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.111
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.064 0.372
DAB1 DAB1: Disabled homolog 1 0.064 0.088
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.064 0.041
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.072
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.062 0.081
RHO RHO, OPN2: Rhodopsin 0.062 0.029
HPN HPN, TMPRSS1: Serine protease hepsin 0.062 0.032
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.062 0.029
GABRR1 N/A 0.062 0.029
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.062 0.029
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.098
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.098
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.061 0.046
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.060 0.115
CNN1 CNN1: Calponin-1 0.059 0.030
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.058 0.097
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.058 0.171
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.058 0.136
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.058 0.275
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.058 0.318
FGL2 FGL2: Fibroleukin precursor 0.058 0.332
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.058 0.372
MSN MSN: Moesin 0.058 0.763
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.058 0.275
PSD TYL: TYL protein 0.058 0.097
DOK1 DOK1: Docking protein 1 0.058 0.461
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.058 0.225
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.058 0.171
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.058 0.461
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.058 1.62
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.058 0.088
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.058 0.111
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.058 0.515
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.056 0.029
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.056 0.040
GLRA1 N/A 0.056 0.029
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.056 0.073
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.113
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.056 0.0818
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.056 0.166
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.056 0.072
ATP2B1 N/A 0.056 0.0453
CCR5 CCR5: CCR5 receptor (Fragment) 0.056 0.166
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.056 0.036
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.055 0.072
FADD FADD, MORT1: Protein FADD 0.055 0.075
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.055 0.0727
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.055 0.032
TLR4 TLR4: Toll-like receptor 4 precursor 0.055 0.0446
CD44 N/A 0.055 0.153
DSTN DSTN, ACTDP, DSN: Destrin 0.054 0.028
SDC4 SDC4: Syndecan-4 precursor 0.054 0.029
TBXA2R TBXA2R: Thromboxane A2 receptor 0.052 0.04
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.052 0.04
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.052 0.225
STMN1 STMN1, LAP18, OP18: Stathmin 0.052 0.097
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.052 0.225
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.052 0.171
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.052 0.275
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
KIAA1688 KIAA1688: KIAA1688 protein (Fragment) 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
PPP1R14C PPP1R14C, KEPI: Protein phosphatase 1 regulatory subunit 14C 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
C9orf88 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
NCAM1 N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
RAPH1 N/A 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
MARK2 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
UBAP2L N/A 0.051 0.051
ITIH3 ITIH3: Inter-alpha-trypsin inhibitor heavy chain H3 precursor 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
IGHM N/A 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
PPP1R1B PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
NF1 NF1: Neurofibromin 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
HLA-A N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHD N/A 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
SPARCL1 SPARCL1: SPARC-like protein 1 precursor 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
SNX2 SNX2, TRG9: Sorting nexin-2 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
SNX12 N/A 0.051 0.051
TP73 TP73, P73: Tumor protein p73 0.051 0.072
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.126
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.051 0.058
SALF GTF2A1L, ALF, GTF2A1LF: TFIIA-alpha and beta-like factor 0.0513 0.029
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.051 0.171
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.051 0.088
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.051 0.088
MT3 MT3: Metallothionein-3 0.049 0.033
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.049 0.100
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.100
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.049 0.029
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
TSC2 TSC2, TSC4: Tuberin 0.049 0.083
MAPK15 N/A 0.049 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.083
MAP2K5 N/A 0.049 0.165
MYO18A 0.049 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.083
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.049 0.032
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.049 0.029
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.048 0.061
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.047 0.034
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.044
AQP4 AQP4: Aquaporin-4 0.047 0.036
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.046 0.041
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
LMO7 N/A 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
PPP1R14A PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
MLLT4 N/A 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
FKBP10 FKBP10, FKBP65, PSEC0056: FK506-binding protein 10 precursor 0.046 0.037
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.046 0.181
RYR1 0.046 0.041
SOS1 SOS1: Son of sevenless homolog 1 0.046 0.113
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.046 0.166
PLEK PLEK, P47: Pleckstrin 0.046 0.561
CENTA1 CENTA1: Centaurin-alpha 1 0.046 0.128
CDKL5 N/A 0.0453 0.123
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.0453 0.098
RYR2 RYR2: Ryanodine receptor 2 0.045 0.041
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.044 0.111
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.044 0.275
GLRB GLRB: Glycine receptor subunit beta precursor 0.044 0.029
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.111
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.075
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.148
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.075
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.148
NIPBL N/A 0.044 0.025
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.041 0.064
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.041 0.304
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.041 0.245
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.041 0.065
ST8SIA4 ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe 0.041 0.027
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.081
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.041 0.225
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.041 0.171
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.041 0.088
MYO3A MYO3A: Myosin IIIA 0.041 0.088
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.041 0.046
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.041 0.162
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.041 1.07
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.052
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
COTL1 COTL1, CLP: Coactosin-like protein 0.04 0.052
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.083
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
RIN2 RIN2, RASSF4: Ras and Rab interactor 2 0.039 0.030
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.039 0.074
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.0263
SDC1 SDC1, SDC: Syndecan-1 precursor 0.039 0.032
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.039 0.037
MARCO MARCO, SCARA2: Macrophage receptor MARCO 0.039 0.025
GJA5 GJA5: Gap junction alpha-5 protein 0.038 0.030
PPP1R1A PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A 0.038 0.030
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.038 0.030
PPP1R14D PPP1R14D, GBPI: Protein phosphatase 1 regulatory subunit 14D 0.038 0.0338
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.045
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.037 0.123
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.037 0.049
FLNA FLNA, FLN, FLN1: Filamin-A 0.037 0.070
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.037 0.026
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.037 0.058
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.037 0.058
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.036 0.126
GSN GSN: Gelsolin precursor 0.036 0.047
CFL2 CFL2: Cofilin-2 0.036 0.047
SVIL SVIL: Supervillin 0.036 0.047
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.035 0.067
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.035 0.029
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.058
ANXA3 ANXA3, ANX3: Annexin A3 0.034 0.0263
TNN TNN: Tenascin-N precursor 0.034 0.042
PEBP1 PEBP1, PBP, PEBP: Phosphatidylethanolamine-binding protein 1 0.034 0.031
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.0338 0.030
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.0338 0.566
BID BID: BH3-interacting domain death agonist 0.034 0.049
MAL2 MAL2: Protein MAL2 0.034 0.034
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.056
AQP1 AQP1, CHIP28: Aquaporin-1 0.033 0.028
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.033 0.044
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.033 0.171
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.033 0.225
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.088
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.033 0.097
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.171
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.033 0.097
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.033 0.088
DYRK3 N/A 0.033 0.088
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.033 0.171
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.033 0.136
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.033 0.077
HD HD, IT15: Huntingtin 0.033 0.155
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.033 0.152
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.033 0.416
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.033 0.251
FUBP1 N/A 0.033 0.127
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.033 0.062
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.033 0.109
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.033 0.052
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.033 0.111
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.033 0.073
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.033 0.181
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.033 0.073
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.155
CDK6 CDK6: Cell division protein kinase 6 0.032 0.152
PRKAA1 N/A 0.032 0.123
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.260
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.032 0.152
WEE1 WEE1: Wee1-like protein kinase 0.032 0.123
STK16 N/A 0.032 0.152
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.032 0.123
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.251
COBL N/A 0.032 0.110
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.307
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.077
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.031 0.041
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.031 0.472
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.0308 0.029
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.0308 0.029
CDC37 CDC37: Hsp90 co-chaperone Cdc37 0.031 0.116
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.116
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.030 0.070
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.034
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.030 0.070
C1QBP C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot 0.030 0.030
CREB1 CREB1: cAMP response element-binding protein 0.030 0.044
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.098
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.030 0.044
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.098
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.098
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.030 0.044
CCNT2 CCNT2: Cyclin-T2 0.030 0.044
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.044
CHAT CHAT: Choline O-acetyltransferase 0.030 0.030
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.030 0.044
DBN1 DBN1, D0S117E: Drebrin 0.030 0.031
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.030 0.046
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.029 0.139
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.029 0.114
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.029 0.069
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.029 0.086
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.029 0.275
HSP90AA1 Hsp89-alpha-delta-N 0.029 0.069
STK10 STK10: Uncharacterized protein STK10 0.029 0.763
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.275
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.029 0.029
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.275
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.029 0.114
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.029 0.086
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.029 0.111
WASPIP N/A 0.029 24.50
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.171
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.029 0.063
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.029 0.056
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.029 0.275
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.029 0.097
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.029 0.763
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.136
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.029 0.069
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.029 0.046
THOC1 THOC1, HPR1: THO complex subunit 1 0.029 0.069
ATM ATM: Serine-protein kinase ATM 0.029 0.171
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.029 0.114
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.029 0.069
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.029 0.461
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.029 0.111
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.029 0.171
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.029 0.029
CTPS CTPS: CTP synthase 1 0.029 0.056
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.029 0.191
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.029 0.062
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.029 0.026
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.251
PVALB PVALB: Parvalbumin alpha 0.029 0.033
TNNC2 TNNC2: Troponin C, skeletal muscle 0.029 0.037
CDK4 CDK4: Cell division protein kinase 4 0.029 0.111
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.136
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.029 0.035
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.372
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.029 0.086
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.029 0.097
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.029 0.275
KIAA0690 N/A 0.029 0.063
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.111
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.058
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
SYK N/A 0.0288 0.0288
TNS1 TNS1, TNS: Tensin-1 0.0288 0.0288
VAV3 VAV-like protein (Fragment) 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
DAPP1 DAPP1, BAM32, HSPC066: Dual adapter for phosphotyrosine and 3-phosphotyrosine an 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
PIK3R1 PIK3R1, GRB1: Phosphatidylinositol 3-kinase regulatory subunit alpha 0.0288 0.0288
PIK3R3 PIK3R3: Phosphatidylinositol 3-kinase regulatory subunit gamma 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
INPP5D N/A 0.0288 0.0288
FGR FGR, RP1-159A19.2-007: Gardner-Rasheed feline sarcoma viral (Fragment) 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
BTK N/A 0.0288 0.0288
TENC1 N/A 0.0288 0.0288
SOCS6 SOCS6, CIS4, SOCS4: Suppressor of cytokine signaling 6 0.0288 0.0288
GRB10 Adapter protein (Fragment) 0.0288 0.0288
BLNK BLNK, SLP65, BASH: B-cell linker protein (Fragment) 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.028 0.026
SPOCK2 SPOCK2, KIAA0275, UNQ269/PRO306, TICN2: Testican-2 precursor 0.0273 0.030
EIF4EBP1 EIF4EBP1: Eukaryotic translation initiation factor 4E-binding protein 1 0.0273 0.053
PMP2 PMP2: Myelin P2 protein 0.027 0.044
AQP2 AQP2: Aquaporin-2 0.027 0.035
FGFR2 N/A 0.027 0.217
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 0.0263 0.034
B2M B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro 0.026 0.046
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.026 0.029
FLII FLII, FLIL: Protein flightless-1 homolog 0.026 0.146
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.026 0.111
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.026 0.171
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.026 0.372
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.026 0.461
CDK5 CDK5: Cell division protein kinase 5 0.026 0.136
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.026 0.114
CDK2 CDK2: Cell division protein kinase 2 0.026 0.111
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.026 0.111
CDK7 CDK7, MO15: Cell division protein kinase 7 0.026 0.136
RPS6KB1 N/A 0.026 0.225
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.026 0.461
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.026 0.088
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.026 0.225
SYMPK SYMPK, SPK: Symplekin 0.026 0.029
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.275
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.026 0.094
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.026 0.139
INPPL1 INPPL1, SHIP2: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 0.0258 0.0258
FES N/A 0.0258 0.0258
ETS2 ETS2: Protein C-ets-2 0.025 0.126
TOM1L1 TOM1L1, SRCASM: TOM1-like protein 1 0.025 0.029
ETV1 ETV1, ER81: ETS translocation variant 1 0.025 0.029
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.0727
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.098
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.044
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.044
0.572
Total Score 6.45E4