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Evidence of Interaction Between TP53 and RAD18

The interaction score between TP53 and RAD18 is 3.07.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology N/A N/A
Domains Domains present in TP53 and RAD18:
Domains in TP53Domains in RAD18
IPR008967 p53-like transcription factor, DNA-binding
IPR002117 p53 tumor antigen
IPR010991 p53, tetramerisation
IPR011615 P53_DNA_bd.
IPR012346 P53_RUNT_DNA_bd.
IPR001841 Zn-finger, RING
IPR006642 Zn-finger Rad18
IPR003034 DNA-binding SAP

The Chi square scores for co-occurrence of domains that are present in TP53 and RAD18 are listed below.

Domain 1Domain 2Chi Square
IPR002117 p53 tumor antigen IPR001841 Zn-finger, RING 0.704097
IPR010991 p53, tetramerisation IPR001841 Zn-finger, RING 0.704097
IPR011615 P53_DNA_bd. IPR001841 Zn-finger, RING 0.704097
IPR012346 P53_RUNT_DNA_bd. IPR001841 Zn-finger, RING 0.704097
IPR008967 p53-like transcription factor, DNA-binding IPR001841 Zn-finger, RING 0.00157184

The background colour of the table refers to:

  • Blue Domain is only present in TP53
  • Yellow Domain is only present in RAD18
  • Green Domain is present in both TP53 and RAD18

 0.034
Post-translational Modifications

Protein: TP53

PTMResidueReference
Acetylation 305 PubMed, HPRD
Acetylation 320 PubMed, HPRD
Acetylation 370 PubMed, HPRD
Acetylation 372 PubMed, HPRD
Acetylation 373 PubMed, HPRD
Acetylation 381 PubMed, HPRD
Acetylation 382 PubMed, HPRD
Deacylation 382 PubMed, HPRD
Dephosphorylation 315 PubMed, HPRD
N6-acetyllysine 305 HPRD
N6-acetyllysine 373 HPRD
N6-acetyllysine 382 HPRD
Phosphorylation 6 PubMed, HPRD
Phosphorylation 9 PubMed, HPRD
Phosphorylation 15 PubMed, HPRD
Phosphorylation 18 PubMed, HPRD
Phosphorylation 20 PubMed, HPRD
Phosphorylation 33 PubMed, HPRD
Phosphorylation 37 PubMed, HPRD
Phosphorylation 46 PubMed, HPRD
Phosphorylation 55 PubMed, HPRD
Phosphorylation 81 PubMed, HPRD
Phosphorylation 155 PubMed, HPRD
Phosphorylation 315 PubMed, HPRD
Phosphorylation 366 PubMed, HPRD
Phosphorylation 371 PubMed, HPRD
Phosphorylation 378 PubMed, HPRD
Phosphorylation 392 PubMed, HPRD
Phosphoserine 15 PubMed, HPRD
Phosphoserine 46 PubMed, HPRD
Phosphoserine 315 PubMed, HPRD
Phosphothreonine 18 PubMed, HPRD
Phosphothreonine 55 PubMed, HPRD
Proteolytic Cleavage 18 PubMed, HPRD
Proteolytic Cleavage 20 PubMed, HPRD
Proteolytic Cleavage 23 PubMed, HPRD
Sumoylation 386 PubMed, HPRD
Ubiquitination 351 PubMed, HPRD
Ubiquitination 357 PubMed, HPRD
Ubiquitination 370 PubMed, HPRD
Ubiquitination 372 PubMed, HPRD
Ubiquitination 373 PubMed, HPRD
Ubiquitination 381 PubMed, HPRD
Ubiquitination 382 PubMed, HPRD
Ubiquitination 386 PubMed, HPRD

Protein: RAD18

PTMResidueReference
Phosphorylation 99 PubMed, HPRD
Phosphorylation 471 PubMed, HPRD
Phosphoserine 99 HPRD
Phosphoserine 471 HPRD
Localisation

Protein: TP53

LocalisationReference
ER HPRD
Nucleus HPRD
Mitochondrion HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: RAD18

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between TP53 and RAD18 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andRAD18. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and RAD18 has 721 interactors of which there are 242 common interactors.

Common InteractorName of Common InteractorScore for TP53-Interactor (?)Score for RAD18-Interactor (?)
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 1.58 0.0688
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 1.58 0.034
PGR PGR, NR3C3: Progesterone receptor 1.00 0.0688
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.964 0.096
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.902 0.0688
PCNA PCNA: Proliferating cell nuclear antigen 0.704 0.908
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.651 0.0688
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.471 0.0688
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.430 0.034
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.430 0.034
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.430 0.034
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.430 0.034
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.430 0.034
DDX21 DDX21: Nucleolar RNA helicase 2 0.430 0.0688
NBN NBN, NBS, NBS1, P95: Nibrin 0.430 0.034
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.430 0.0688
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.385 0.062
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.385 0.030
SP3 SP3: Transcription factor Sp3 0.347 0.034
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.304 0.030
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.260 0.0688
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.260 0.034
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.260 0.034
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 0.254 0.0688
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.233 0.034
YY1 YY1: Transcriptional repressor protein YY1 0.233 0.034
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.233 0.034
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.233 0.034
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.216 0.030
MATR3 MATR3, KIAA0723: Matrin-3 0.210 0.034
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.210 0.034
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.210 0.034
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.188 0.034
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.188 0.034
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.188 0.0688
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.188 0.034
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.188 0.030
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.188 0.062
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.188 0.030
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.188 0.0688
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.187 0.034
MYB MYB: Myb proto-oncogene protein 0.176 0.034
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.162 0.0688
TP73 TP73, P73: Tumor protein p73 0.156 0.034
ZNF267 ZNF267: Zinc finger protein 267 0.155 0.034
XRCC1 XRCC1: DNA-repair protein XRCC1 0.155 0.034
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.155 0.034
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.146 0.034
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.141 0.030
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.139 0.062
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.139 0.062
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.139 0.0688
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.139 0.0688
IRF3 IRF3: Interferon regulatory factor 3 0.132 0.034
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.132 0.034
CBX3 CBX3: Chromobox protein homolog 3 0.129 0.034
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.034
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.129 0.030
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.129 0.908
ZFX ZFX: Zinc finger X-chromosomal protein 0.127 0.034
HIVEP1 N/A 0.127 0.034
ZNF335 ZNF335: Zinc finger protein 335 0.127 0.034
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.127 0.034
SALL1 SALL1, SAL1: Sal-like protein 1 0.125 0.034
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.124 0.030
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.114 0.034
MTF1 MTF1: Metal regulatory transcription factor 1 0.114 0.030
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.114 0.034
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.114 0.0688
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.114 0.034
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.114 0.030
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.114 0.030
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.114 0.034
ZBTB16 ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16 0.111 0.030
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.111 0.034
STAT6 STAT6: Signal transducer and activator of transcription 6 0.111 0.034
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.096 0.034
STAT2 STAT2: Signal transducer and activator of transcription 2 0.096 0.034
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.096 8.01
SATB2 SATB2, KIAA1034: DNA-binding protein SATB2 0.090 0.034
TGIF2 TGIF2: Homeobox protein TGIF2 0.087 0.034
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.087 0.034
BRPF1 BRPF1, BR140: Peregrin 0.086 0.030
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.086 0.034
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.086 0.030
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.086 0.062
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.086 0.062
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.086 0.034
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.083 0.034
UHRF1 0.083 0.034
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.083 0.034
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.083 0.034
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.034
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.083 0.034
ZNF579 ZNF579: Zinc finger protein 579 0.083 0.034
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.083 0.034
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.083 0.034
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.083 0.034
C20orf18 N/A 0.083 0.0688
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.0818 0.034
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.078 0.025
MYBL2 MYBL2, BMYB: Myb-related protein B 0.078 0.034
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.078 0.0688
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.078 0.025
LSM3 LSM3, MDS017: U6 snRNA-associated Sm-like protein LSm3 0.078 0.427
MDM4 MDM4, MDMX: Mdm4 protein 0.077 0.034
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.077 0.034
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.077 0.0688
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.077 0.034
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.034
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.076 0.028
EEF2 EEF2, EF2: Elongation factor 2 0.075 0.030
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.034
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.075 0.062
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.075 0.034
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.075 0.083
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.075 0.034
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.075 0.0688
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.075 0.034
RNF20 0.075 0.034
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.075 0.030
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.075 0.030
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.075 0.034
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.075 0.034
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.075 0.030
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.069 0.034
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.069 0.034
ZNF551 N/A 0.069 0.030
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.069 0.034
LIG4 LIG4: DNA ligase 4 0.069 0.030
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.069 0.030
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.067 0.034
SUMO2 SUMO2, SMT3B, SMT3H2: Small ubiquitin-related modifier 2 precursor 0.0668 0.030
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.066 0.062
VCP VCP: Transitional endoplasmic reticulum ATPase 0.066 0.030
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.034
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 0.030
PHF10 N/A 0.063 0.034
CRLF3 N/A 0.063 0.028
SH3BP3 0.062 0.034
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.062 0.034
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.062 0.034
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.057 0.0688
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.057 0.028
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.056 0.0688
SP1 SP1, TSFP1: Transcription factor Sp1 0.056 0.030
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.056 0.034
STAT4 STAT4: Signal transducer and activator of transcription 4 0.055 0.034
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.055 0.034
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.054 0.0688
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.054 0.0688
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.052 0.034
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.0688
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.052 0.034
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.034
RNF11 RNF11, CGI-123: RING finger protein 11 0.050 0.034
SMARCA1 SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1 0.050 0.030
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.049 0.034
STAT3 0.049 0.034
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.049 0.0688
KLF5 KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5 0.049 0.034
BNC1 BNC1, BNC: Zinc finger protein basonuclin-1 0.049 0.034
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.048 0.0688
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.048 0.0688
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.047 0.034
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.047 0.0688
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.046 0.030
ARMET ARMET, ARP: Protein ARMET precursor 0.046 0.028
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.046 0.034
SYMPK SYMPK, SPK: Symplekin 0.046 0.034
CUL5 CUL5, VACM1: Cullin-5 0.046 0.0688
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.0688
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.046 0.028
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.0453 0.034
KLC2 KLC2: Kinesin light chain 2 0.044 0.034
EGR1 EGR1, ZNF225: Early growth response protein 1 0.044 0.030
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.034
VDR VDR, NR1I1: Vitamin D3 receptor 0.043 0.0688
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0425 0.034
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.034
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.034
XRCC4 N/A 0.0425 0.028
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.0425 0.034
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.0425 0.034
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.0425 0.034
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.041 0.062
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.040 0.030
XPO1 XPO1, CRM1: Exportin-1 0.040 0.030
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.040 0.030
PPARG CREB3L2-PPARgamma 0.039 0.0688
TCEB3 TCEB3, MSTP059: Transcription elongation factor B polypeptide 3 0.038 0.034
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.036 0.052
HD HD, IT15: Huntingtin 0.036 0.034
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.036 16.30
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.035 0.034
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.034 0.034
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.034 0.028
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.028
FN1 N/A 0.034 0.028
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.034 0.028
MAGED2 N/A 0.033 0.034
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.032 0.034
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.0688
BACH1 BACH1: Transcription regulator protein BACH1 0.032 0.034
CASP3 CASP3, CPP32: Caspase-3 precursor 0.032 0.034
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.032 0.030
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.032 0.030
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.032 0.062
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.032 0.034
RPS10 RPS10: 40S ribosomal protein S10 0.032 0.062
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.032 0.030
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.031 0.0688
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.031 0.028
NFIB N/A 0.031 0.034
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.031 0.0688
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.030 0.028
CNTN4 CNTN4: Contactin-4 precursor 0.030 0.028
CNTN1 CNTN1: Contactin-1 precursor 0.030 0.028
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.029 0.034
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.029 0.028
SMCX JARID1C, DXS1272E, SMCX, XE169: Histone demethylase JARID1C 0.029 0.030
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.028 0.034
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.034
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.034
DSP DSP: Desmoplakin 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.034
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.034
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.028 0.0688
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.027 0.0688
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.026 0.0688
CIC CIC, KIAA0306: Protein capicua homolog 0.025 0.028
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.034
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.034
NIPBL N/A 0.025 0.030
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.034
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.030
DIDO1 N/A 0.025 0.030
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.030
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.034
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.034
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.034
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.030
0.228
Total Score 3.07