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Evidence of Interaction Between PDGFRB and CBL

The interaction score between PDGFRB and CBL is 3.15E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between PDGFRB and CBL = -0.11

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.48E-3
Orthology
OrganismPDGFRB OrthologueCBL OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00022296 0.132 IPI00292856 0.232
  • InVivo

Get References From PubMed
human IPI00027721 0.325 IPI00292856 0.232
human IPI00018335 1 IPI00292856 0.232
human IPI00021396 1 IPI00292856 0.232
human IPI00293565 0.322 IPI00292856 0.232
human IPI00005722 0.081 IPI00292856 0.232
  • InVivo

Get References From PubMed
worm P34892 0.084 Q19019 0.232
worm O76698 1 Q19019 0.232
worm Q21038 1 Q19019 0.232
worm Q21041 1 Q19019 0.232

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 1.07
Domains Domains present in PDGFRB and CBL:
Domains in PDGFRBDomains in CBL
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.
IPR001841 Zn-finger, RING
IPR000449 Ubiquitin-associated domain
IPR000980 SH2 motif
IPR000217 Tubulin
IPR003153 Adaptor protein Cbl, N-terminal
IPR011992 EF-Hand_type.
IPR013090 Phospholip_A2_AS.

The Chi square scores for co-occurrence of domains that are present in PDGFRB and CBL are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR003599 Immunoglobulin subtype IPR000980 SH2 motif 66.4833
IPR003598 Immunoglobulin C-2 type IPR000980 SH2 motif 64.7072
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR013151 Immunoglobulin. IPR000980 SH2 motif 36.9251
IPR008266 Tyrosine protein kinase, active site IPR001841 Zn-finger, RING 16.2425
IPR011009 Protein kinase-like IPR001841 Zn-finger, RING 15.6712
IPR000719 Protein kinase IPR011992 EF-Hand_type. 15.5567
IPR001245 Tyrosine protein kinase IPR001841 Zn-finger, RING 15.1425
IPR000719 Protein kinase IPR001841 Zn-finger, RING 14.0542
IPR008266 Tyrosine protein kinase, active site IPR003153 Adaptor protein Cbl, N-terminal 13.6309
IPR011009 Protein kinase-like IPR011992 EF-Hand_type. 9.34155
IPR001245 Tyrosine protein kinase IPR003153 Adaptor protein Cbl, N-terminal 9.19853
IPR007110 Immunoglobulin-like IPR011992 EF-Hand_type. 6.99538
IPR001245 Tyrosine protein kinase IPR011992 EF-Hand_type. 6.38624
IPR000719 Protein kinase IPR003153 Adaptor protein Cbl, N-terminal 3.06419
IPR011009 Protein kinase-like IPR003153 Adaptor protein Cbl, N-terminal 3.04324
IPR003599 Immunoglobulin subtype IPR011992 EF-Hand_type. 2.41821
IPR008266 Tyrosine protein kinase, active site IPR011992 EF-Hand_type. 1.24952
IPR011009 Protein kinase-like IPR000217 Tubulin 0.524874
IPR003598 Immunoglobulin C-2 type IPR011992 EF-Hand_type. 0.490157
IPR011009 Protein kinase-like IPR000449 Ubiquitin-associated domain 0.41941
IPR001245 Tyrosine protein kinase IPR000449 Ubiquitin-associated domain 0.348773
IPR013151 Immunoglobulin. IPR011992 EF-Hand_type. 0.0700765
IPR008266 Tyrosine protein kinase, active site IPR000217 Tubulin 0.0503676
IPR000719 Protein kinase IPR000217 Tubulin 0.0254403
IPR008266 Tyrosine protein kinase, active site IPR000449 Ubiquitin-associated domain 0.00515077
IPR000719 Protein kinase IPR000449 Ubiquitin-associated domain 0.00138935
IPR001245 Tyrosine protein kinase IPR000217 Tubulin 0.00033966

The background colour of the table refers to:

  • Blue Domain is only present in PDGFRB
  • Yellow Domain is only present in CBL
  • Green Domain is present in both PDGFRB and CBL

 0.540
Post-translational Modifications

Protein: PDGFRB

PTMResidueReference
Dephosphorylation 562 PubMed, HPRD
Dephosphorylation 579 PubMed, HPRD
Dephosphorylation 740 PubMed, HPRD
Dephosphorylation 751 PubMed, HPRD
Dephosphorylation 771 PubMed, HPRD
Dephosphorylation 857 PubMed, HPRD
Dephosphorylation 1009 PubMed, HPRD
Dephosphorylation 1021 PubMed, HPRD
Phosphorylation 579 PubMed, HPRD
Phosphorylation 581 PubMed, HPRD
Phosphorylation 716 PubMed, HPRD
Phosphorylation 740 PubMed, HPRD
Phosphorylation 751 PubMed, HPRD
Phosphorylation 763 PubMed, HPRD
Phosphorylation 771 PubMed, HPRD
Phosphorylation 775 PubMed, HPRD
Phosphorylation 857 PubMed, HPRD
Phosphorylation 1009 PubMed, HPRD
Phosphorylation 1021 PubMed, HPRD
Phosphotyrosine 751 PubMed, HPRD
Phosphotyrosine 857 PubMed, HPRD

Protein: CBL

PTMResidueReference
Phosphorylation 371 PubMed, HPRD
Phosphorylation 619 PubMed, HPRD
Phosphorylation 623 PubMed, HPRD
Phosphorylation 639 PubMed, HPRD
Phosphorylation 642 PubMed, HPRD
Phosphorylation 667 PubMed, HPRD
Phosphorylation 669 PubMed, HPRD
Phosphorylation 674 PubMed, HPRD
Phosphorylation 675 PubMed, HPRD
Phosphorylation 700 PubMed, HPRD
Phosphorylation 731 PubMed, HPRD
Phosphorylation 774 PubMed, HPRD
Phosphoserine 669 HPRD
Phosphotyrosine 371 PubMed, HPRD
Phosphotyrosine 674 HPRD
Phosphotyrosine 700 HPRD
Phosphotyrosine 774 HPRD
Localisation

Protein: PDGFRB

LocalisationReference
Plasma membrane HPRD

Protein: CBL

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PDGFRB and CBL that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PDGFRB andCBL. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PDGFRB has 1323 interactors and CBL has 1376 interactors of which there are 709 common interactors.

Common InteractorName of Common InteractorScore for PDGFRB-Interactor (?)Score for CBL-Interactor (?)
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 1.01E3 0.878
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 600.00 0.064
NCK2 NCK2: Cytoplasmic protein NCK2 600.00 30.80
CRKL CRKL: Crk-like protein 536.00 0.064
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 532.00 0.286
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 422.00 8.34
STAT5B STAT5B: Signal transducer and activator of transcription 5B 372.00 0.097
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 315.00 0.090
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 281.00 0.655
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 281.00 0.064
VAV1 VAV1, VAV: Proto-oncogene vav 281.00 0.073
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 277.00 0.577
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 277.00 0.577
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 265.00 0.046
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 250.00 0.073
JAK2 JAK2: Tyrosine-protein kinase JAK2 250.00 0.655
HCK N/A 250.00 0.655
STAT6 STAT6: Signal transducer and activator of transcription 6 250.00 0.073
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 232.00 0.148
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 183.00 214.00
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 147.00 5.94
GRAP GRAP: GRB2-related adapter protein 133.00 2.13
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 112.00 0.318
KIT KIT: Mast/stem cell growth factor receptor precursor 112.00 0.318
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 84.00 0.073
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 82.20 173.00
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 74.00 0.577
JUP JUP, CTNNG, DP3: Junction plakoglobin 37.90 0.027
SHC2 N/A 29.70 1.29
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 15.80 0.111
PRKCG PRKCG, PKCG: Protein kinase C gamma type 12.50 0.097
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 12.50 0.097
LOC392481 N/A 2.58 1.07
SHC4 SHC-transforming protein 4 2.58 1.07
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 1.13 0.644
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 0.098
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 0.980
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.109
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.109
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 0.980
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.109
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 0.878
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.916 0.140
BMX N/A 0.902 0.644
STAT3 0.878 0.098
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 0.577
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.731 0.072
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.731 0.902
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 1.13
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 1.01
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.654 0.072
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.654 0.655
SYK SYK: Tyrosine-protein kinase SYK 0.654 0.808
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.654 0.655
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 0.577
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.644 0.081
JAK1 0.644 0.577
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.081
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.051
CRK CRK: Proto-oncogene C-crk 0.617 0.051
GRB10 N/A 0.617 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.051
CSK CSK: Tyrosine-protein kinase CSK 0.586 0.655
APS SH2B2, APS: SH2B adapter protein 2 0.586 0.073
LYN LYN: Tyrosine-protein kinase Lyn 0.586 0.655
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.581 0.731
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.581 0.081
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.581 0.100
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 0.731
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.046
RIN1 RIN1: Ras and Rab interactor 1 0.520 0.097
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.520 277.00
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.372 0.041
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.360 0.109
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.123
STAT2 STAT2: Signal transducer and activator of transcription 2 0.320 0.152
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.318 0.097
STAT4 STAT4: Signal transducer and activator of transcription 4 0.286 0.111
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.275 0.041
TNC TNC, HXB: Tenascin precursor 0.275 0.037
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.217
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.251 0.320
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.251 0.063
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.251 0.063
VWF VWF, F8VWF: von Willebrand factor precursor 0.245 0.041
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.233 0.041
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.225 0.041
CNN3 CNN3: Calponin-3 0.202 0.065
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.202 0.041
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.202 0.045
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.191 0.051
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.045
GHR GHR: Growth hormone receptor precursor 0.191 0.051
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.181 0.041
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.181 0.058
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.181 0.041
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.181 0.041
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.171 0.073
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.171 0.318
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.166 0.051
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.0688
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.0688
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.0688
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.0688
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.540
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.0688
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.0688
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.0688
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.0688
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.0688
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.0688
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.483
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.0688
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.0688
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.0688
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.0688
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.034
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.0688
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.540
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.0688
KIR3DL1 N/A 0.165 0.0688
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.165 0.034
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.540
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.0688
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.0688
FN1 N/A 0.165 0.0688
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.0688
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.152 0.051
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.152 0.045
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.152 0.051
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.152 0.403
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.152 0.045
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.152 0.045
SELE SELE, ELAM1: E-selectin precursor 0.152 0.025
DAB2 DAB2, DOC2: Disabled homolog 2 0.148 0.097
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.062
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.483
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.062
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.483
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.062
BSG N/A 0.148 0.062
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.062
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 0.062
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.483
ATRN N/A 0.148 0.030
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.062
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.062
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.136 0.318
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.136 0.361
INSR INSR: Insulin receptor precursor 0.136 0.318
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.136 0.286
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.136 0.361
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.136 0.318
FYN N/A 0.129 0.143
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.129 0.143
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.127 0.025
CTTN CTTN, EMS1: Src substrate cortactin 0.126 0.065
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.126 0.072
IRS1 IRS1: Insulin receptor substrate 1 0.126 0.152
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.125 0.045
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.123 0.051
MET MET: Hepatocyte growth factor receptor precursor 0.123 0.403
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.063
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.045
PVR PVR, PVS: Poliovirus receptor precursor 0.123 0.051
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.123 0.051
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.045
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.041
F3 F3: Tissue factor precursor 0.123 0.051
EGF EGF: Pro-epidermal growth factor precursor 0.123 0.051
PRLR PRLR: Prolactin receptor precursor 0.123 0.063
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.123 0.051
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.123 0.045
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.051
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.123 0.046
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.113 0.097
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.112 0.029
PARVA PARVA, MXRA2: Alpha-parvin 0.111 0.064
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.111 0.361
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.111 0.445
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.111 0.445
NEO1 NEO1, NGN: Neogenin precursor 0.111 0.057
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.111 0.057
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.110 0.045
SORL1 SORL1: Sortilin-related receptor precursor 0.110 0.051
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.110 0.025
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.110 0.045
LILRB1 N/A 0.110 0.063
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.110 0.051
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.110 0.045
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.110 0.051
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.110 0.051
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.110 0.045
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.109
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.109
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.049
PSCD2 N/A 0.109 0.109
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.098
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.148
CGN N/A 0.109 0.034
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.109
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.049
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.109
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
CNN2 CNN2: Calponin-2 0.109 0.109
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.109
NF2 NF2, SCH: Merlin 0.109 0.165
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.109 0.036
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.049
PPEF1 N/A 0.109 0.165
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.109 0.051
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.051
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.045
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.045
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.109 0.063
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.109 0.063
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.109 0.025
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.109 0.063
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.109 0.041
ITGB4 N/A 0.109 0.051
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.051
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.109 0.051
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.109 0.318
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.051
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.109 0.051
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.109 0.045
EPOR EPOR: Erythropoietin receptor precursor 0.109 0.051
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.109 0.031
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.101 0.051
S100A3 S100A3, S100E: Protein S100-A3 0.100 0.037
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.099 0.028
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.051
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.098 0.045
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.098 0.051
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.098 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.098 0.051
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.051
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.098 0.051
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.098 0.063
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.098 0.051
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.098 0.045
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.098 0.051
PTPRZ1 N/A 0.098 0.037
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.098 0.051
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.098 0.051
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.098 0.100
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.098 0.045
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.051
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.098 0.051
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.098
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.044
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.098
ARHGEF7 N/A 0.098 0.098
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.098
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.098
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.098 0.030
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.025
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.036
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.098
ELMO1 N/A 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 0.878
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.025
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.036
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.098
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.098
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.044
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.098
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.148
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.041
DCC DCC: Netrin receptor DCC precursor 0.097 0.057
MEP1A MEP1A: Meprin A subunit alpha precursor 0.097 0.037
MEP1B MEP1B: Meprin A subunit beta precursor 0.097 0.057
ASGR1 ASGR1: Asialoglycoprotein receptor 1 0.097 0.028
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.445
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.318
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.097 0.361
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.152
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.090 0.064
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.064
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.097
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.090 0.073
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.088 0.041
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.088 0.445
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.088 0.046
CRLF3 N/A 0.088 0.045
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.086 0.156
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.083 0.0688
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.034
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.034
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.0688
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.0688
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.083 0.034
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.083 0.034
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.034
OPTC OPTC, OPT: Opticin precursor 0.083 0.034
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.034
S100A7 S100A7, PSOR1: Protein S100-A7 0.081 0.032
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.081 0.0263
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.045
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.081 0.045
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.081 0.123
SPTAN1 N/A 0.081 0.072
PRG2 PRG2, MBP: Bone marrow proteoglycan precursor 0.081 0.025
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 1.20
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.081 0.081
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.081 0.051
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.081 0.032
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.081 0.030
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0782 0.0338
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.077 0.051
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.030
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.062
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.030
JAG2 JAG2: Jagged-2 precursor 0.075 0.030
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.098
TTN N/A 0.073 0.136
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.073 0.029
PLD2 PLD2: Phospholipase D2 0.073 0.064
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.073 0.136
DLG2 DLG2: Disks large homolog 2 0.073 0.046
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.073 0.028
TLN2 TLN2: Uncharacterized protein TLN2 0.073 0.064
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.073 0.058
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.073 0.035
RASA3 RASA3: Ras GTPase-activating protein 3 0.073 0.073
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.073 0.090
PLD1 PLD1: Phospholipase D1 0.073 0.073
RDX RDX: Radixin 0.073 0.064
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.073 0.041
SORBS3 SORBS3, SCAM1: Vinexin 0.073 43.20
ROCK1 ROCK1: Rho-associated protein kinase 1 0.0727 0.152
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.0727 0.033
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0727 0.072
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.0727 0.081
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.109
GRLF1 N/A 0.072 0.127
F5 F5: Coagulation factor V precursor 0.072 0.031
IRS2 IRS2: Insulin receptor substrate 2 0.072 0.109
GAB1 GAB1: GRB2-associated-binding protein 1 0.072 0.109
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.081
S100B S100B: Protein S100-B 0.072 0.029
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.072 0.123
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.097
CETN1 CETN1, CEN1, CETN: Centrin-1 0.0688 0.047
NSBP1 NSBP1: Nucleosome-binding protein 1 0.0688 0.028
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.065 0.090
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.065 0.027
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.065 0.073
GMIP GMIP: GEM-interacting protein 0.065 0.033
PSCD4 PSCD4, CYT4: Cytohesin-4 0.065 0.090
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.065 0.136
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.065 0.029
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.065 0.111
CD2AP CD2AP: CD2-associated protein 0.065 0.090
FNBP1 N/A 0.065 0.111
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.065 0.073
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.065 0.064
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.065 0.111
LCP1 LCP1, PLS2: Plastin-2 0.065 0.073
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.065 0.111
CXorf9 N/A 0.065 0.111
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.065 0.111
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.065 0.058
CSPG2 N/A 0.065 0.051
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.065 0.171
VASP VASP: Vasodilator-stimulated phosphoprotein 0.065 0.072
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.065 0.029
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.065 0.072
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.065 0.152
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.123
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.065 0.0263
GAB2 N/A 0.065 0.109
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.065 0.081
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.065 0.037
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.445
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.064 0.111
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.064 0.073
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.064 0.041
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.064 0.088
VIL2 N/A 0.064 0.064
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.064
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.064 0.097
DAB1 DAB1: Disabled homolog 1 0.064 0.097
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.064 0.037
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.148
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.064 0.111
TLN1 TLN1: Uncharacterized protein TLN1 0.064 0.064
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.041
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.064 0.097
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.123
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.062 0.051
GABRR1 N/A 0.062 0.051
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.062 0.051
GP9 GP9: Platelet glycoprotein IX precursor 0.062 0.025
HPN HPN, TMPRSS1: Serine protease hepsin 0.062 0.028
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.148
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.061 0.045
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.060 0.075
CNN1 CNN1: Calponin-1 0.059 0.0338
MSN MSN: Moesin 0.058 0.064
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.058 0.111
PSD TYL: TYL protein 0.058 0.058
DOK1 DOK1: Docking protein 1 0.058 0.111
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.058 0.111
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.058 0.073
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.058 0.064
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.058 0.090
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.058 0.073
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.058 0.064
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.058 0.088
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.058 0.073
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.058 0.111
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.058 0.058
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.058 0.123
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.056 0.041
GLRA1 N/A 0.056 0.057
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.046
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.056 0.051
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.056 0.063
CCR5 CCR5: CCR5 receptor (Fragment) 0.056 0.063
FADD FADD, MORT1: Protein FADD 0.055 0.045
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.055 0.045
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.055 0.025
GP1BA N/A 0.055 0.025
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.055 0.051
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.052 0.111
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.052 0.029
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.052 0.064
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
MARK2 N/A 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
UBAP2L N/A 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
IGHM N/A 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
HLA-A N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHD N/A 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.046
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
C9orf88 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
NCAM1 N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
RAPH1 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.152
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.051 0.098
TP73 TP73, P73: Tumor protein p73 0.051 0.109
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.051 0.027
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.051 0.088
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.051 0.088
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.051 0.097
WWC2 WW and C2 domain containing 2 0.051 0.033
MT3 MT3: Metallothionein-3 0.049 0.026
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.049 0.152
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.051
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.109
DCN DCN: Decorin precursor 0.049 0.034
MAP2K5 N/A 0.049 0.109
MYO18A 0.049 0.098
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
MAPK15 N/A 0.049 0.165
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.049 0.041
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.048 0.045
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.030
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.046 0.045
LMO7 N/A 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
SOS1 SOS1: Son of sevenless homolog 1 0.046 0.136
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.046 0.111
RYR1 0.046 0.071
CENTA1 CENTA1: Centaurin-alpha 1 0.046 0.041
PLEK PLEK, P47: Pleckstrin 0.046 0.152
CDKL5 N/A 0.0453 0.109
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.0453 0.111
RYR2 RYR2: Ryanodine receptor 2 0.045 0.045
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.044 0.073
GLRB GLRB: Glycine receptor subunit beta precursor 0.044 0.037
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.073
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.148
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.044
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.044
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.044
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.148
NIPBL N/A 0.044 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.044
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.148
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.041 0.097
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.041 0.136
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.041 0.111
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.097
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.041 0.109
MAGED2 N/A 0.041 0.026
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.041 0.097
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.041 0.111
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.041 0.071
MYO3A MYO3A: Myosin IIIA 0.041 0.097
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.041 0.064
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.041 0.0924
MYH9 MYH9: Myosin-9 0.041 0.111
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.041 0.111
DSP DSP: Desmoplakin 0.04 0.083
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.049
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.04
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.063
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.039 0.045
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.038 0.047
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.045
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.037 0.064
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.037 0.065
FLNA FLNA, FLN, FLN1: Filamin-A 0.037 0.072
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.037 0.073
RAB11FIP5 RAB11FIP5, GAF1, KIAA0857, RIP11: Rab11 family-interacting protein 5 0.037 0.051
KERA KERA: Keratocan precursor 0.037 0.025
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.037 0.109
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.037 0.088
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.037 0.088
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.046
ANXA3 ANXA3, ANX3: Annexin A3 0.034 0.051
TNN TNN: Tenascin-N precursor 0.034 0.034
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.0338 0.038
SYTL4 Endocrine transmitter regulatory protein 0.034 0.052
MAL2 MAL2: Protein MAL2 0.034 0.034
BID BID: BH3-interacting domain death agonist 0.034 0.028
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.033 0.029
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.033
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.033 0.064
DYRK3 N/A 0.033 0.225
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.033 0.064
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.033 0.097
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.033 0.111
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.033 0.064
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.136
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.033 0.111
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.111
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.033 0.064
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.033 0.123
FUBP1 N/A 0.033 0.037
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.033 0.123
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.033 0.171
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.033 0.055
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.033 0.111
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.033 0.123
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.033 0.097
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.033 0.097
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.033 0.097
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.032 0.191
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.081
GAS2 GAS2: Growth arrest-specific protein 2 0.032 0.072
WEE1 WEE1: Wee1-like protein kinase 0.032 0.136
STK16 N/A 0.032 0.152
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.032 0.191
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.109
COBL N/A 0.032 0.065
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.152
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.0453
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.081
PRKAA1 N/A 0.032 0.251
CDK6 CDK6: Cell division protein kinase 6 0.032 0.111
TNFRSF10C TNFRSF10C, DCR1, UNQ321/PRO366, LIT, TRAILR3, TRID: Tumor necrosis factor recept 0.031 0.051
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.031 0.045
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.034
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.042
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.030 0.053
CCNT2 CCNT2: Cyclin-T2 0.030 0.025
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.030
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.148
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.148
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.030 0.025
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.030 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.030 0.025
CREB1 CREB1: cAMP response element-binding protein 0.030 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.148
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.030 0.047
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.030 0.037
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.097
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.029 0.049
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.111
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.029 0.073
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.029 0.049
WASPIP N/A 0.029 0.073
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.029 0.111
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.029 0.111
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.029 0.136
THOC1 THOC1, HPR1: THO complex subunit 1 0.029 0.073
ATM ATM: Serine-protein kinase ATM 0.029 0.111
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.029 0.073
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.111
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.029 0.136
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.029 0.064
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.029 0.111
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.029 0.041
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.029 0.033
STK10 STK10: Uncharacterized protein STK10 0.029 0.111
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.111
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.029 0.029
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.029 0.111
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.029 0.032
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.111
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.029 0.152
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.029 0.097
IGFALS IGFALS, ALS: Insulin-like growth factor-binding protein complex acid labile chai 0.029 0.028
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.090
CDK4 CDK4: Cell division protein kinase 4 0.029 0.111
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.111
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.111
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.029 0.097
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.037
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.034
DRD2 DRD2: D(2) dopamine receptor 0.028 0.034
PMP2 PMP2: Myelin P2 protein 0.027 0.026
FGFR2 N/A 0.027 0.141
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.026 0.090
CDK5 CDK5: Cell division protein kinase 5 0.026 0.097
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.026 0.111
CDK2 CDK2: Cell division protein kinase 2 0.026 0.111
CDK7 CDK7, MO15: Cell division protein kinase 7 0.026 0.136
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.026 0.111
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.026 0.088
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.026 0.111
RPS6KB1 N/A 0.026 0.097
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.111
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.026 0.046
FLII FLII, FLIL: Protein flightless-1 homolog 0.026 0.051
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.026 0.090
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.026 0.136
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.026 0.033
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.026 0.033
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.026 0.111
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.026 0.111
FES N/A 0.0258 0.0258
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.152
OCLN OCLN: Occludin 0.025 0.031
ETS2 ETS2: Protein C-ets-2 0.025 0.109
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.025 0.030
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.062
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.062
0.572
Total Score 3.15E4