Home
Advanced Search
Help
Update History
Statistics
Downloads
The Barton Group
<<< Back to FLT1

Evidence of Interaction Between FLT1 and GRAP

The interaction score between FLT1 and GRAP is 3.38E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between FLT1 and GRAP = -0.03

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology
OrganismFLT1 OrthologueGRAP OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00021396 1 IPI00299763 0.071
human IPI00293565 0.322 IPI00299763 0.071
human IPI00005722 0.081 IPI00299763 0.071
human IPI00021396 1 IPI00472451 0.077
human IPI00293565 0.322 IPI00472451 0.077
human IPI00005722 0.081 IPI00472451 0.077
human IPI00021396 1 IPI00410080 0.074
human IPI00293565 0.322 IPI00410080 0.074
human IPI00005722 0.081 IPI00410080 0.074
human IPI00021396 1 IPI00013981 0.053
  • InVitro

Get References From PubMed
human IPI00293565 0.322 IPI00013981 0.053
human IPI00005722 0.081 IPI00013981 0.053
human IPI00021396 1 IPI00328867 0.05
human IPI00293565 0.322 IPI00328867 0.05
human IPI00005722 0.081 IPI00328867 0.05
human IPI00021396 1 IPI00399054 0.058
  • InVitro

Get References From PubMed
human IPI00293565 0.322 IPI00399054 0.058
human IPI00005722 0.081 IPI00399054 0.058
worm P34892 0.084 P29355 0.106
worm O76698 1 P29355 0.106
worm Q21038 1 P29355 0.106
worm Q21041 1 P29355 0.106

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.58
Domains Domains present in FLT1 and GRAP:
Domains in FLT1Domains in GRAP
IPR000719 Protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR009135 Vascular endothelial growth factor receptor 1, VEGFR1
IPR001452 SH3
IPR000108 Neutrophil cytosol factor 2
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in FLT1 and GRAP are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR008266 Tyrosine protein kinase, active site IPR001452 SH3 164.706
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR008266 Tyrosine protein kinase, active site IPR000108 Neutrophil cytosol factor 2 43.9279
IPR001824 Receptor tyrosine kinase, class III IPR001452 SH3 32.2626
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR007110 Immunoglobulin-like IPR001452 SH3 20.3228
IPR001824 Receptor tyrosine kinase, class III IPR000108 Neutrophil cytosol factor 2 9.24001
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001452 SH3 8.64336
IPR000719 Protein kinase IPR000108 Neutrophil cytosol factor 2 4.72045
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000108 Neutrophil cytosol factor 2 3.30483
IPR007110 Immunoglobulin-like IPR000108 Neutrophil cytosol factor 2 2.23913

The background colour of the table refers to:

  • Blue Domain is only present in FLT1
  • Yellow Domain is only present in GRAP
  • Green Domain is present in both FLT1 and GRAP

 0.217
Post-translational Modifications

Protein: FLT1

PTMResidueReference
Dephosphorylation 1213 PubMed, HPRD
Phosphorylation 794 PubMed, HPRD
Phosphorylation 1169 PubMed, HPRD
Phosphorylation 1213 PubMed, HPRD
Phosphorylation 1242 PubMed, HPRD
Phosphorylation 1327 PubMed, HPRD
Phosphorylation 1333 PubMed, HPRD
Phosphotyrosine 1213 PubMed, HPRD
Phosphotyrosine 1242 PubMed, HPRD
Phosphotyrosine 1327 PubMed, HPRD
Phosphotyrosine 1333 PubMed, HPRD

Protein: GRAP

PTMResidueReference
Localisation

Protein: FLT1

LocalisationReference
Plasma membrane HPRD
Secreted HPRD
Cytoplasm HPRD

Protein: GRAP

LocalisationReference
Cytoplasm HPRD
Transitive Score

The common interactors between FLT1 and GRAP that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between FLT1 andGRAP. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , FLT1 has 1443 interactors and GRAP has 466 interactors of which there are 222 common interactors.

Common InteractorName of Common InteractorScore for FLT1-Interactor (?)Score for GRAP-Interactor (?)
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 1.01E3 114.00
NCK2 NCK2: Cytoplasmic protein NCK2 676.00 13.20
CRKL CRKL: Crk-like protein 600.00 0.028
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 214.00 2.13
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 207.00 7.56
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 183.00 133.00
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 130.00 8.58
KIT KIT: Mast/stem cell growth factor receptor precursor 127.00 61.50
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 112.00 61.50
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 112.00 55.50
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 82.20 0.128
SHC2 N/A 29.70 1.29
LOC392481 N/A 2.58 1.07
SHC4 SHC-transforming protein 4 2.58 1.07
INSL3 JAK3: Tyrosine-protein kinase JAK3 1.13 0.244
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.027
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.027
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 0.265
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 0.265
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.027
BMX N/A 0.902 0.197
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.902 0.0308
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.878 2.04
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.878 0.027
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.878 0.265
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.808 0.274
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.731 0.197
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 0.244
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.655 0.141
APS SH2B2, APS: SH2B adapter protein 2 0.655 0.028
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 0.177
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.655 0.156
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.654 0.402
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.654 0.0308
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.050
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.644 0.174
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.644 0.0308
HCK N/A 0.586 0.156
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.586 0.028
CSK CSK: Tyrosine-protein kinase CSK 0.586 0.440
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.586 0.218
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.586 0.402
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.586 0.218
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.586 0.360
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.586 0.036
LYN LYN: Tyrosine-protein kinase Lyn 0.586 0.218
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.586 31.80
SYK SYK: Tyrosine-protein kinase SYK 0.586 0.244
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.520 0.305
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.520 0.402
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.483 9.04
VAV1 VAV1, VAV: Proto-oncogene vav 0.465 0.036
JAK1 0.465 0.305
STAT6 STAT6: Signal transducer and activator of transcription 6 0.465 13.20
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.323 2.98
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.286 0.029
STAT4 STAT4: Signal transducer and activator of transcription 4 0.286 0.035
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.286 0.032
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.251 0.129
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.027
MET MET: Hepatocyte growth factor receptor precursor 0.191 0.143
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.191 0.145
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.171 61.50
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.171 0.179
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.171 0.145
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.171 61.50
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.171 0.115
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.217
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.217
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.217
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.148 0.272
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.148 0.217
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.195
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.148 0.126
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.195
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.195
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.145 0.041
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.145 0.305
FYN N/A 0.145 0.305
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.145 0.0308
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.136 0.179
ALK ALK: ALK tyrosine kinase receptor precursor 0.136 0.094
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.136 0.128
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.136 0.128
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.136 0.115
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.136 0.145
RIN3 N/A 0.130 0.028
VAV3 VAV3: Protein vav-3 0.128 0.028
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.113 76.00
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.111 0.128
INSR INSR: Insulin receptor precursor 0.111 61.50
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.111 0.115
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.110 0.032
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.110 0.032
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.110 0.032
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.110 0.039
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.110 0.032
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.110 0.032
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.110 0.039
PSCD2 N/A 0.109 0.027
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.027
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.027
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.027
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.027
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.027
NF2 NF2, SCH: Merlin 0.109 0.027
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.109 0.032
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.032
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.0308
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.032
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.098 0.039
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.032
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.098 0.027
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 0.237
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 27.60
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.098 0.027
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.097 0.145
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.097 0.039
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.097 0.179
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.090 4.72
SORBS3 SORBS3, SCAM1: Vinexin 0.090 7.56
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.088 0.032
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.088 0.032
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.088 0.032
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.088 0.032
CRLF3 N/A 0.088 0.032
CTTN CTTN, EMS1: Src substrate cortactin 0.081 0.674
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 0.244
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.075 9.04
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.073 1.21
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.0727 0.0308
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0727 0.0308
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.065 0.036
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.065 7.31
PSCD4 PSCD4, CYT4: Cytohesin-4 0.065 0.028
FNBP1 N/A 0.065 1.93
CXorf9 N/A 0.065 0.036
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.065 0.060
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.065 0.044
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.065 0.036
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.065 0.036
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.065 0.028
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.065 0.028
ROCK1 ROCK1: Rho-associated protein kinase 1 0.065 0.0308
DOK1 DOK1: Docking protein 1 0.064 0.028
RASA3 RASA3: Ras GTPase-activating protein 3 0.064 0.028
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.064 0.028
VIL2 N/A 0.058 0.036
CD2AP CD2AP: CD2-associated protein 0.058 0.028
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.058 1.02
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.058 0.036
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.058 0.028
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.058 0.050
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.056 0.039
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.052 7.31
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.0288
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.0288
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.0288
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.0288
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.032
CCR5 CCR5: CCR5 receptor (Fragment) 0.049 0.032
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.027
MAP2K5 N/A 0.049 0.027
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.027
MAPK15 N/A 0.049 0.027
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.049 0.036
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 1.29
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.0258
FLT4 VEGFR3 long form 0.046 0.0258
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.0308
MUSK MUSK: Muscle, skeletal receptor tyrosine protein kinase precursor 0.044 0.200
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.04 0.027
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.04 0.027
MAPKAPK5 N/A 0.04 0.027
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.04 0.027
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.04 0.027
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.04 0.027
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.04 0.027
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.04 0.027
SOS1 SOS1: Son of sevenless homolog 1 0.037 2.44
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.033 0.028
CDK2 CDK2: Cell division protein kinase 2 0.033 0.028
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.033 0.050
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.033 0.029
STK16 N/A 0.032 0.0308
STYK1 STYK1, NOK: Tyrosine protein-kinase STYK1 0.0308 0.200
RET urf-ret: Urf-ret protein 0.0308 0.162
HLA-DOA HLA-DOA, HLA-DNA, HLA-DZA: HLA class II histocompatibility antigen, DO alpha cha 0.0308 0.032
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.029 0.036
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.029 0.028
RPS6KB1 N/A 0.029 0.044
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.028
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.041
ATM ATM: Serine-protein kinase ATM 0.029 0.060
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.029 0.028
WASPIP N/A 0.029 9.63
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.029 0.050
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.029 0.041
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.029 0.0308
PRKAA1 N/A 0.029 0.0308
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.028
CDK6 CDK6: Cell division protein kinase 6 0.029 0.0308
CDK4 CDK4: Cell division protein kinase 4 0.029 0.028
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
ROR2 ROR2, NTRKR2: Tyrosine-protein kinase transmembrane receptor ROR2 precursor 0.028 0.128
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.027 0.036
FGFR2 N/A 0.027 0.217
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
ASB2 ASB2: Ankyrin repeat and SOCS box protein 2 0.027 0.027
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.026 0.028
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.026 0.036
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.036
FES N/A 0.0258 0.0258
0.572
Total Score 3.38E4