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Evidence of Interaction Between F2 and DAK

The interaction score between F2 and DAK is 2.50.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between F2 and DAK = 0.87

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.027
Orthology N/A N/A
Domains No domains were used in calculating likelihood of interaction N/A
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation No localisation data was used in calculating likelihood of interaction
Transitive Score

The common interactors between F2 and DAK that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between F2 andDAK. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , F2 has 909 interactors and DAK has 59 interactors of which there are 43 common interactors.

Common InteractorName of Common InteractorScore for F2-Interactor (?)Score for DAK-Interactor (?)
F10 F10: Coagulation factor X precursor 2.47E3 0.027
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 50.50 0.027
ITIH4 ITIH4, IHRP, PRO1851, ITIHL1, PK120: Inter-alpha-trypsin inhibitor heavy chain H 50.50 0.027
SERPINA4 SERPINA4, KST, PI4: Kallistatin precursor 50.50 0.027
SERPINF2 SERPINF2, AAP, PLI: Alpha-2-antiplasmin precursor 50.50 0.027
SERPIND1 SERPIND1, HCF2: Heparin cofactor 2 precursor 50.50 0.027
SERPINA6 SERPINA6, CBG: Corticosteroid-binding globulin precursor 16.80 0.027
APCS APCS, PTX2: Serum amyloid P-component precursor 5.75 0.027
HGFAC HGFAC: Hepatocyte growth factor activator precursor 5.75 0.027
AMBP AMBP, HCP, ITIL: AMBP protein precursor [Contains: Alpha-1-microglobulin 5.75 0.027
HPX HPX: Hemopexin precursor 5.75 0.027
HP HP: Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta c 5.75 0.027
F12 F12: Coagulation factor XII precursor 5.75 0.027
VTN VTN: Vitronectin precursor 5.75 0.027
PROC PROC: Vitamin K-dependent protein C precursor 5.15 0.027
APOC4 APOC2, APC2: Apolipoprotein C-II precursor 5.03 0.027
ORM1 ORM1, AGP1: Alpha-1-acid glycoprotein 1 precursor 5.03 0.027
APOC3 APOC3: Apolipoprotein C-III precursor 5.03 0.027
HAMP HAMP, HEPC, UNQ487/PRO1003, LEAP1: Hepcidin precursor 5.03 0.027
C8G C8G: Complement component C8 gamma chain precursor 5.03 0.027
APOA1 APOA1: Apolipoprotein A-I precursor 5.03 0.027
ORM2 ORM2, AGP2: Alpha-1-acid glycoprotein 2 precursor 5.03 0.027
RNASE4 ANG, RNASE5: Angiogenin precursor 5.03 0.027
HRG HRG: Histidine-rich glycoprotein precursor 5.03 0.027
ASGR2 ASGR2: Asialoglycoprotein receptor 2 3.16 0.027
HPN HPN, TMPRSS1: Serine protease hepsin 2.83 0.027
APOC4 APOC4: Apolipoprotein C-IV precursor 0.954 0.027
SAA4 SAA4, CSAA: Serum amyloid A-4 protein precursor 0.954 0.027
HPR HPR: Haptoglobin-related protein precursor 0.881 0.027
SLC37A4 G6PC, G6PT: Glucose-6-phosphatase 0.236 0.027
GNMT GNMT: Glycine N-methyltransferase 0.144 0.027
ADH1C ADH1C, ADH3: Alcohol dehydrogenase 1C 0.126 0.027
GAMT GAMT, hCG_21569: cDNA FLJ76206, highly similar to Homo sapiens guanidinoacetate 0.082 0.027
RBP4 RBP4, PRO2222: Plasma retinol-binding protein precursor 0.049 0.027
APOC1 APOC1: Apolipoprotein C-I precursor 0.049 0.082
CES2 N/A 0.049 0.027
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.042 0.027
C4B C4B, XXbac-BCX116I9.7-001, XXbac-BPG116M5.7-001: C4B1 0.027 0.027
RARRES2 RARRES2, TIG2: Retinoic acid receptor responder protein 2 precursor 0.027 0.027
LR8 TMEM176B, LR8: Transmembrane protein 176B 0.027 0.027
SLC22A1 hOCT1, SLC22A1, RP11-288H12.1-001: Organic cation transporter 1 0.027 0.027
SLC22A7 SLC22A7, RP11-480N24.7-001, hCG_19011: Solute carrier family 22 0.027 0.027
MUCDHL N/A 0.027 0.027
0.228
Total Score 2.50