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Evidence of Interaction Between ACTG1 and CFL2

The interaction score between ACTG1 and CFL2 is 2.76E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismACTG1 OrthologueCFL2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00008603 0.452 IPI00457282 0.421
human IPI00021440 1 IPI00457282 0.421
human IPI00025416 0.452 IPI00457282 0.421
human IPI00023006 0.435 IPI00457282 0.421
human IPI00021428 0.403 IPI00457282 0.421
human IPI00003269 0.238 IPI00457282 0.421
human IPI00008603 0.452 IPI00166133 0.136
human IPI00021440 1 IPI00166133 0.136
human IPI00025416 0.452 IPI00166133 0.136
human IPI00023006 0.435 IPI00166133 0.136
human IPI00021428 0.403 IPI00166133 0.136
human IPI00003269 0.238 IPI00166133 0.136
human IPI00008603 0.452 IPI00012011 0.75
  • Other
  • InVitro

Get References From PubMed
human IPI00021440 1 IPI00012011 0.75
  • Other
  • Y2H

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human IPI00025416 0.452 IPI00012011 0.75
human IPI00023006 0.435 IPI00012011 0.75
  • Other
  • InVivo
  • Y2H
  • InVitro

Get References From PubMed
human IPI00021428 0.403 IPI00012011 0.75
  • Other
  • InVitro
  • Y2H

Get References From PubMed
human IPI00003269 0.238 IPI00012011 0.75
bakers yeast YFL039C 1 YLL050C 0.75
  • Y2H
  • Other
  • SyntheticLethal

Get References From PubMed
worm P10983 0.818 Q9UAU4 1
fly P02572 0.917 P45594 1
fly P02572 0.917 Q9VWR1 0.432

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 3.01
Domains Domains present in ACTG1 and CFL2:
Domains in ACTG1Domains in CFL2
IPR004000 Actin/actin-like
IPR004001 Actin
IPR002108 Actin-binding, cofilin/tropomyosin type

The Chi square scores for co-occurrence of domains that are present in ACTG1 and CFL2 are listed below.

Domain 1Domain 2Chi Square
IPR004001 Actin IPR002108 Actin-binding, cofilin/tropomyosin type 61.9947
IPR004000 Actin/actin-like IPR002108 Actin-binding, cofilin/tropomyosin type 54.8645

The background colour of the table refers to:

  • Blue Domain is only present in ACTG1
  • Yellow Domain is only present in CFL2
  • Green Domain is present in both ACTG1 and CFL2

 0.165
Post-translational Modifications

Protein: ACTG1

PTMResidueReference
N-acetylaspartate 2 PubMed, HPRD
Phosphotyrosine 166 HPRD
Phosphotyrosine 218 HPRD
Phosphotyrosine 294 HPRD

Protein: CFL2

PTMResidueReference
Dephosphorylation 3 PubMed, HPRD
Phosphorylation 3 PubMed, HPRD
Localisation

Protein: ACTG1

LocalisationReference
Golgi HPRD
Plasma membrane HPRD
Nucleolus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: CFL2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between ACTG1 and CFL2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between ACTG1 andCFL2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , ACTG1 has 1176 interactors and CFL2 has 936 interactors of which there are 659 common interactors.

Common InteractorName of Common InteractorScore for ACTG1-Interactor (?)Score for CFL2-Interactor (?)
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 1.02E3 0.025
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 621.00 0.025
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 202.00 1.33
ACTB ACTG1, ACTB, ACTG: Actin, cytoplasmic 2 186.00 67.20
DSTN DSTN, ACTDP, DSN: Destrin 183.00 0.714
GSN GSN: Gelsolin precursor 170.00 0.025
PLD2 PLD2: Phospholipase D2 157.00 0.025
WASL WASL: Neural Wiskott-Aldrich syndrome protein 131.00 1.33
WASPIP N/A 122.00 0.025
CFL1 CFL1, CFL: Cofilin-1 122.00 1.33
EEF1A1 EEF1A1: Elongation factor 1-alpha 73.00 0.025
CORO1C CORO1C, CRNN4: Coronin-1C 53.80 0.683
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 40.60 0.025
LCP1 LCP1, PLS2: Plastin-2 40.60 0.025
DIAPH1 Diaphanous 1 20.60 0.025
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 20.60 0.025
CAP1 CAP1, CAP: Adenylyl cyclase-associated protein 1 12.60 0.232
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 7.92 0.047
CNN2 CNN2: Calponin-2 7.88 0.025
PRKCG PRKCG, PKCG: Protein kinase C gamma type 7.14 0.025
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 6.64 0.025
TAGLN TAGLN, SM22, WS3-10: Transgelin 5.88 0.025
CTTN CTTN, EMS1: Src substrate cortactin 5.88 0.025
CNN3 CNN3: Calponin-3 4.67 0.025
ACTA2 ACTA2, ACTSA, GIG46, ACTVS: Actin, aortic smooth muscle 4.28 32.20
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 3.97 0.025
NULL N/A 3.01 0.064
HSP90AA1 Hsp89-alpha-delta-N 2.47 0.025
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 1.94 0.025
EEF1A2 EEF1A2, EEF1AL, STN: Elongation factor 1-alpha 2 0.890 0.025
STAT6 STAT6: Signal transducer and activator of transcription 6 0.822 0.025
VAV1 VAV1, VAV: Proto-oncogene vav 0.763 0.025
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.763 0.025
FLII FLII, FLIL: Protein flightless-1 homolog 0.763 0.025
CAP2 CAP2: Adenylyl cyclase-associated protein 2 0.593 3.01
NULL N/A 0.593 0.119
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.515 0.148
FLNA FLNA, FLN, FLN1: Filamin-A 0.515 0.028
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.461 0.025
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.461 0.025
SEC24B SEC24B: Protein transport protein Sec24B 0.461 0.025
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.461 0.025
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.461 0.025
MVP MVP, LRP: Major vault protein 0.430 0.028
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.425 0.137
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.416 0.028
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.385 0.047
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.385 0.148
MSN MSN: Moesin 0.385 0.025
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.372 0.025
CCT8 CCT8: Uncharacterized protein CCT8 0.372 0.025
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.307 0.028
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.307 0.028
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.275 0.025
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.275 0.025
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.275 0.025
TCP1 CCT1, CCTA, TCP1: T-complex protein 1 subunit alpha 0.275 0.025
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.275 0.025
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.269 0.028
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.260 0.028
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.260 0.028
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.241 0.025
TLN1 TLN1: Uncharacterized protein TLN1 0.233 0.025
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.233 0.047
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.233 0.025
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.233 0.025
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.233 0.025
JAK1 0.233 0.047
HCK N/A 0.233 0.047
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.233 0.047
DOK1 DOK1: Docking protein 1 0.233 0.025
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.233 0.025
PSCD4 PSCD4, CYT4: Cytohesin-4 0.233 0.025
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.225 0.025
GMFB GMFB: Glia maturation factor beta 0.225 0.025
HSPD1 0.225 0.025
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.225 0.025
ACTN1 ACTN1: Alpha-actinin-1 0.225 0.025
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.225 0.025
VASP VASP: Vasodilator-stimulated phosphoprotein 0.210 0.028
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.210 0.028
ROCK1 ROCK1: Rho-associated protein kinase 1 0.210 0.028
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.210 0.028
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.210 0.028
CORO1A CORO1A, CORO1: Coronin-1A 0.203 0.998
CHP CHP: Calcium-binding protein p22 0.188 0.025
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.188 0.025
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.188 0.025
ACTA1 ACTA1, ACTA: Actin, alpha skeletal muscle 0.172 0.682
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.171 0.025
ACTC ACTC1, ACTC: Actin, alpha cardiac muscle 1 0.169 0.682
PPEF1 N/A 0.165 0.028
ZYX ZYX: Zyxin 0.163 0.028
LIMS1 N/A 0.163 0.028
GAB2 N/A 0.155 0.028
IRS2 IRS2: Insulin receptor substrate 2 0.155 0.028
ACTG2 ACTG2, ACTA3, ACTL3, ACTSG: Actin, gamma-enteric smooth muscle 0.152 0.682
DBN1 DBN1, D0S117E: Drebrin 0.152 0.028
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.025
MYO18A 0.148 0.025
SVIL SVIL: Supervillin 0.148 0.025
SNX3 N/A 0.148 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.148 0.025
COTL1 COTL1, CLP: Coactosin-like protein 0.148 0.025
CXorf9 N/A 0.146 0.025
LPXN LPXN, LDLP: Leupaxin 0.146 0.025
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.139 0.047
CD2AP CD2AP: CD2-associated protein 0.139 0.025
VIL2 N/A 0.139 0.025
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.139 0.025
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.139 0.025
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.139 0.025
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.137 0.098
PLD1 PLD1: Phospholipase D1 0.136 0.025
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.136 0.025
TPT1 TPT1: Translationally-controlled tumor protein 0.129 0.025
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.129 0.025
HNRPK N/A 0.129 0.025
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.129 0.025
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.129 12.00
QARS QARS: Glutaminyl-tRNA synthetase 0.129 0.025
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.129 0.047
LYN LYN: Tyrosine-protein kinase Lyn 0.129 0.047
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.129 0.025
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.129 0.025
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.129 0.025
RPS10 RPS10: 40S ribosomal protein S10 0.129 0.025
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.129 0.025
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.129 0.025
GMIP GMIP: GEM-interacting protein 0.129 0.025
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.129 0.025
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.129 0.025
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.129 0.025
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.127 0.028
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.123 0.028
DKFZp686D0972 ACT: Actin-like protein (Fragment) 0.119 0.064
NULL N/A 0.119 0.064
CRKL CRKL: Crk-like protein 0.118 0.025
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.114 0.025
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.114 1.33
MDN1 MDN1, KIAA0301: Midasin 0.114 0.025
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.111 0.025
COBL N/A 0.110 0.028
TMSL8 TMSL8, TMSNB: NB thymosin beta 0.109 0.028
MYO3A MYO3A: Myosin IIIA 0.099 0.025
PARVA PARVA, MXRA2: Alpha-parvin 0.099 0.025
SPTAN1 N/A 0.098 0.028
MCF2 MCF2, DBL: Proto-oncogene DBL 0.098 0.028
VIL1 VIL1, VIL: Villin-1 0.097 0.025
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.096 0.028
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.096 0.028
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.096 0.028
PSD TYL: TYL protein 0.088 0.025
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.087 0.028
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.087 0.028
MARK2 N/A 0.087 0.028
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.087 0.052
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.087 0.028
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.087 0.028
IFI35 N/A 0.087 0.028
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.087 0.028
FUBP1 N/A 0.087 0.028
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.087 0.028
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.086 0.025
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.086 0.025
RASA3 RASA3: Ras GTPase-activating protein 3 0.086 0.025
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.086 0.030
S100A16 S100A16, AAG13: Protein S100-A16 0.083 0.028
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.083 0.028
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.083 0.028
DNM3 DNM3: Uncharacterized protein DNM3 0.083 0.028
LNK SH2B3, LNK: SH2B adapter protein 3 0.083 0.028
NF2 NF2, SCH: Merlin 0.083 0.028
PSCD2 N/A 0.083 0.028
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.0818 0.098
LIMK2 LIMK2: LIM domain kinase 2 0.080 0.028
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.078 0.025
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.078 0.025
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.078 0.025
VCP VCP: Transitional endoplasmic reticulum ATPase 0.078 0.025
RPL8 RPL8: 60S ribosomal protein L8 0.078 0.025
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.025
RPS6KB1 N/A 0.078 0.047
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.025
CSK CSK: Tyrosine-protein kinase CSK 0.078 0.047
FRG1 FRG1: Protein FRG1 0.078 0.025
MAD1L1 MAD1L1, MAD1, TXBP181: Mitotic spindle assembly checkpoint protein MAD1 0.078 0.025
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.078 0.025
STK10 STK10: Uncharacterized protein STK10 0.078 0.025
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.078 0.025
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.078 0.025
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.078 0.025
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.078 0.047
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.078 0.025
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.078 0.025
SYK SYK: Tyrosine-protein kinase SYK 0.078 0.047
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.078 0.025
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.078 0.025
COPA COPA: Coatomer subunit alpha 0.078 0.025
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.025
FNBP1 N/A 0.078 0.025
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.078 0.025
SAPS3 N/A 0.078 0.025
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.078 0.047
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.078 0.025
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.025
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.078 0.025
PPARBP N/A 0.078 0.025
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.078 0.025
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.078 0.025
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.078 0.025
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.078 0.047
EEF2 EEF2, EF2: Elongation factor 2 0.078 0.025
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.025
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.078 0.025
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.078 0.025
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.025
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.078 0.025
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.078 0.025
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.025
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.078 0.025
GSK3B N/A 0.078 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.075 0.025
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.047
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.075 0.025
STAT3 0.075 0.025
ARHGEF7 N/A 0.075 0.025
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.075 0.025
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.075 0.025
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.075 0.025
ELMO1 N/A 0.075 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.025
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.075 0.025
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.075 0.025
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.075 0.025
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.075 0.047
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.075 0.025
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.075 0.025
CORO1B CORO1B: Coronin-1B 0.0732 0.998
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.0727 0.029
SAT SAT1, SAT: Diamine acetyltransferase 1 0.070 0.028
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.028
DNM2 N/A 0.070 0.028
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.070 0.028
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.070 0.028
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.070 0.028
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.028
AHNAK AHNAK: AHNAK protein 0.070 0.028
API5 N/A 0.070 0.028
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.028
MPG N/A 0.070 0.028
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.070 0.028
DAPP1 N/A 0.070 0.028
SRPR SRPR: Uncharacterized protein SRPR 0.070 0.028
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.070 0.028
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.070 0.028
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.069 0.025
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.069 0.025
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.069 0.025
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.069 0.025
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.069 0.025
STAM2 STAM2: Signal transducing adapter molecule 2 0.069 0.025
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.063 0.025
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.063 0.025
XPO1 XPO1, CRM1: Exportin-1 0.063 0.025
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.063 0.025
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.063 0.025
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.063 0.047
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.063 0.025
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.025
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.063 0.025
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.063 0.025
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.063 0.025
KLHDC4 N/A 0.063 0.025
COPE COPE: Coatomer subunit epsilon 0.063 0.025
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.063 0.025
RP2 RP2: Protein XRP2 0.063 0.025
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.063 0.025
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.063 0.025
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.025
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.063 0.025
TXNRD1 TXNRD1: Thioredoxin reductase 1, cytoplasmic precursor 0.063 0.025
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.063 0.025
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.063 0.025
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.063 0.025
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.063 0.025
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.063 0.148
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.063 0.025
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.063 0.025
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.063 0.025
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.063 0.025
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.063 0.025
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.063 0.025
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.025
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.063 0.025
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.063 0.025
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.063 0.025
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.063 0.047
LDHB LDHB: L-lactate dehydrogenase B chain 0.063 0.025
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.063 0.025
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.063 0.025
NRAS NRAS, HRAS1: GTPase NRas precursor 0.063 0.025
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.062 0.028
GAB1 GAB1: GRB2-associated-binding protein 1 0.062 0.028
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.056 0.025
DAB2 DAB2, DOC2: Disabled homolog 2 0.056 0.025
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.056 0.025
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.056 0.025
RDX RDX: Radixin 0.056 0.025
APS SH2B2, APS: SH2B adapter protein 2 0.056 0.025
SORBS3 SORBS3, SCAM1: Vinexin 0.056 0.025
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.056 0.028
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.055 0.028
IRS1 IRS1: Insulin receptor substrate 1 0.055 0.028
S100A7 S100A7, PSOR1: Protein S100-A7 0.055 0.028
CORO2A CORO2A, IR10, WDR2: Coronin-2A 0.053 1.79
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.052 0.052
PHB2 PHB2, BAP, REA: Prohibitin-2 0.052 0.028
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.052 0.052
HD HD, IT15: Huntingtin 0.052 0.028
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.028
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.028
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.052 0.028
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.052 0.028
ABCF1 N/A 0.052 0.028
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.052 0.028
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.052 0.028
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.028
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.052 0.028
CHUK N/A 0.052 0.028
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.052 0.028
CIITA CIITA, MHC2TA: MHC class II transactivator 0.052 0.028
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.052 0.028
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.052 0.028
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.051 0.098
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.050 0.047
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.050 0.025
DAB1 DAB1: Disabled homolog 1 0.050 0.025
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.050 0.025
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.050 0.025
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.050 0.025
TNNC1 TNNC1, TNNC: Troponin C, slow skeletal and cardiac muscles 0.049 0.028
S100A3 S100A3, S100E: Protein S100-A3 0.049 0.028
BMX N/A 0.049 0.052
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.049 0.052
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.049 0.028
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.049 0.025
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.049 0.025
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.049 0.047
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.049 0.025
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.049 0.025
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.048 0.028
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.048 0.028
LMO6 LMO6: LIM domain only protein 6 0.047 0.025
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.047 0.025
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.046 0.047
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.046 0.025
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.046 0.025
EXOC2 N/A 0.046 0.025
DCP1A DCP1A, SMIF: mRNA-decapping enzyme 1A 0.046 0.025
PPIG PPIG: Peptidyl-prolyl cis-trans isomerase G 0.046 0.025
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.046 0.025
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.025
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.046 0.025
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.046 0.025
BRPF1 BRPF1, BR140: Peregrin 0.046 0.025
CRK N/A 0.046 0.025
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.046 0.025
ATM ATM: Serine-protein kinase ATM 0.046 0.025
CASP3 CASP3, CPP32: Caspase-3 precursor 0.046 0.025
CDK7 CDK7, MO15: Cell division protein kinase 7 0.046 0.025
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.025
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.046 0.025
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 0.025
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.046 0.025
PRDX1 PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1 0.046 0.025
SHC1 SHC1, RP11-307C12.1-001, hCG_1997126: SHC 0.046 0.025
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.046 0.047
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.046 0.025
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.046 0.025
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.046 0.025
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.046 0.047
NCK2 NCK2: Cytoplasmic protein NCK2 0.046 0.025
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.046 0.025
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.046 0.025
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.046 0.025
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.025
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.046 0.025
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.046 0.025
PTPN11 N/A 0.046 0.025
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.046 0.025
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.046 0.025
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.046 0.025
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.044 0.047
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.044 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.044 46.90
LIMA1 LIMA1, EPLIN, PP624, SREBP3: LIM domain and actin-binding protein 1 0.043 0.025
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.0425 0.028
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.0425 0.028
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.0425 0.028
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.0425 0.052
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.028
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.0425 0.052
IPO7 IPO7: Uncharacterized protein IPO7 0.0425 0.028
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.028
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.0425 0.028
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.0425 0.028
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.0425 0.028
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.0425 0.028
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.0425 0.028
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.0425 0.052
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.0425 0.028
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.0425 0.052
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.0425 0.028
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.0425 0.028
CORO2B CORO2B, KIAA0925: Coronin-2B 0.0421 0.038
HMGCS2 HMGCS2: Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor 0.0421 0.642
GAS2 GAS2: Growth arrest-specific protein 2 0.0416 0.028
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.040 0.025
TLN2 TLN2: Uncharacterized protein TLN2 0.040 0.025
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.040 0.025
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.040 0.025
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.038 0.025
CSE1L CSE1L, CAS, XPO2: Exportin-2 0.038 0.025
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.038 0.025
SH3BP5 N/A 0.038 0.025
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.038 0.025
THOC1 THOC1, HPR1: THO complex subunit 1 0.038 0.025
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.038 0.025
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.038 0.025
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.038 0.025
APEH APEH, D3F15S2, D3S48E, DNF15S2: Acylamino-acid-releasing enzyme 0.038 0.025
AIP AIP, XAP2: AH receptor-interacting protein 0.038 0.025
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.038 0.025
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.038 0.025
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.038 0.047
TK1 TK1: Thymidine kinase, cytosolic 0.038 0.025
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.038 0.025
DPP4 DPP4, ADCP2, CD26: Dipeptidyl peptidase 4 0.038 0.025
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.038 0.025
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.038 0.025
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.038 0.025
GPI GPI: Glucose-6-phosphate isomerase 0.038 0.025
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.038 0.025
EVL N/A 0.038 0.025
CTPS CTPS: CTP synthase 1 0.038 0.025
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.038 0.025
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.038 0.025
TBCE TBCE: Tubulin-specific chaperone E 0.038 0.025
CDK4 CDK4: Cell division protein kinase 4 0.038 0.025
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.038 0.047
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.038 0.025
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.038 0.025
CAT CAT: Catalase 0.038 0.025
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.038 0.025
KIAA0690 N/A 0.038 0.025
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.025
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.025
CDK2 CDK2: Cell division protein kinase 2 0.038 0.025
HDLBP HDLBP, HBP, VGL: Vigilin 0.038 0.025
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.038 0.025
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.038 0.025
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.038 0.025
FHL1 FHL1, SLIM1: Four and a half LIM domains protein 1 0.035 0.028
CRIP2 CRIP2, CRP2: Cysteine-rich protein 2 0.034 0.028
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.0333 0.0333
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.032 0.109
UBAP2 N/A 0.032 0.028
TRRAP N/A 0.032 0.028
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.032 0.028
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.032 0.028
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.032 0.028
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.028
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.028
STK16 N/A 0.032 0.052
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.032 0.052
ESPL1 N/A 0.032 0.028
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.032 0.028
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.032 0.683
LPP LPP: Lipoma-preferred partner 0.031 0.028
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.030 0.030
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.029 0.036
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.025
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.029 0.025
DYNC1I2 N/A 0.029 0.025
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.029 0.025
MAGED2 N/A 0.029 0.025
DLG1 N/A 0.029 0.025
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.029 0.047
RACGAP1 RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1 0.029 0.025
THOP1 THOP1: Thimet oligopeptidase 0.029 0.025
RRAS RRAS: Ras-related protein R-Ras precursor 0.029 0.025
MTHFD1 MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic 0.029 0.025
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.029 0.025
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.029 0.025
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.029 0.025
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.029 0.025
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.029 0.025
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.029 0.025
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.029 0.025
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.029 0.047
YWHAE YWHAE: 14-3-3 protein epsilon 0.029 0.025
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.029 0.025
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.029 0.025
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.029 0.025
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.029 0.025
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.029 0.025
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.029 0.025
SYMPK SYMPK, SPK: Symplekin 0.029 0.025
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.029 0.025
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.029 0.025
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.028 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.028
NCF4 N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.028
PTPN7 N/A 0.028 0.028
PHLDB2 N/A 0.028 0.028
LNX1 N/A 0.028 0.028
CACNB2 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
CASP8 CASP8, MCH5: Caspase-8 precursor 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.028 0.028
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.028 0.028
MATK 0.028 0.028
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.028
C9orf88 N/A 0.028 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.028 0.028
MAPK15 N/A 0.028 0.052
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.028 0.165
PKP4 PKP4: Plakophilin-4 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.028 0.052
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.028 0.028
AXIN1 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.028 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.028 0.028
MAP2K5 N/A 0.028 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.028 0.028
AMPH AMPH, AMPH1: Amphiphysin 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
CDC42 N/A 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.028
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.028 0.025
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.028 22.50
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.026 0.028
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.026 0.028
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.028
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.026 0.028
PRKAA1 N/A 0.026 0.028
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.052
MAP2K5 N/A 0.026 0.028
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.026 0.028
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.028
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.026 0.028
RAC1 N/A 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.025 0.025
DBNL N/A 0.025 0.025
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
NIPBL N/A 0.025 0.025
BCR N/A 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.025 0.025
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.025 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
RAB5B RAB5B: Ras-related protein Rab-5B 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.025
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.025
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.025 0.047
CAMK2A N/A 0.025 0.025
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
SCRIB N/A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.025 0.025
PRKCB1 N/A 0.025 0.025
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.025 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
GIT2 N/A 0.025 0.025
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.025 0.047
MAP2K3 N/A 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
EPN2 N/A 0.025 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.047
GRK6 N/A 0.025 0.025
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.025 0.047
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.025
TSC2 TSC2, TSC4: Tuberin 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.047
BCOR N/A 0.025 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.025
CAMKK1 N/A 0.025 1.33
CDC2 CDC2: Cell division control protein 2 homolog 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.025
0.347
Total Score 2.76E4