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Evidence of Interaction Between KIT and STAT5A

The interaction score between KIT and STAT5A is 1.11E5.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between KIT and STAT5A = 0.28

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

2.88E-3
Orthology
OrganismKIT OrthologueSTAT5A OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00018335 0.132 IPI00103415 1
human IPI00021396 0.132 IPI00103415 1
human IPI00018335 0.132 IPI00000106 0.075
human IPI00021396 0.132 IPI00000106 0.075
human IPI00018335 0.132 IPI00298887 0.082
  • InVivo

Get References From PubMed

human IPI00021396 0.132 IPI00298887 0.082
worm O76698 0.132 Q9NAD6 1
worm Q21038 0.132 Q9NAD6 1
worm Q21041 0.132 Q9NAD6 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

1.07
Domains Domains present in KIT and STAT5A:
Domains in KITDomains in STAT5A
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.
IPR008967 p53-like transcription factor, DNA-binding
IPR000980 SH2 motif
IPR001217 STAT protein
IPR011992 EF-Hand_type.
IPR012345 STAT_DNA_bd.

The Chi square scores for co-occurrence of domains that are present in KIT and STAT5A are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR003599 Immunoglobulin subtype IPR000980 SH2 motif 66.4833
IPR003598 Immunoglobulin C-2 type IPR000980 SH2 motif 64.7072
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR013151 Immunoglobulin. IPR000980 SH2 motif 36.9251
IPR008266 Tyrosine protein kinase, active site IPR012345 STAT_DNA_bd. 22.9582
IPR008266 Tyrosine protein kinase, active site IPR001217 STAT protein 22.9582
IPR000719 Protein kinase IPR011992 EF-Hand_type. 15.5567
IPR001245 Tyrosine protein kinase IPR012345 STAT_DNA_bd. 11.9355
IPR001245 Tyrosine protein kinase IPR001217 STAT protein 11.9355
IPR011009 Protein kinase-like IPR011992 EF-Hand_type. 9.34155
IPR007110 Immunoglobulin-like IPR011992 EF-Hand_type. 6.99538
IPR001245 Tyrosine protein kinase IPR011992 EF-Hand_type. 6.38624
IPR000719 Protein kinase IPR012345 STAT_DNA_bd. 2.68473
IPR000719 Protein kinase IPR001217 STAT protein 2.68473
IPR003599 Immunoglobulin subtype IPR011992 EF-Hand_type. 2.41821
IPR011009 Protein kinase-like IPR012345 STAT_DNA_bd. 1.35691
IPR011009 Protein kinase-like IPR001217 STAT protein 1.35691
IPR008266 Tyrosine protein kinase, active site IPR011992 EF-Hand_type. 1.24952
IPR001245 Tyrosine protein kinase IPR008967 p53-like transcription factor, DNA-binding 0.940239
IPR007110 Immunoglobulin-like IPR012345 STAT_DNA_bd. 0.70476
IPR007110 Immunoglobulin-like IPR001217 STAT protein 0.70476
IPR003598 Immunoglobulin C-2 type IPR011992 EF-Hand_type. 0.490157
IPR000719 Protein kinase IPR008967 p53-like transcription factor, DNA-binding 0.163761
IPR008266 Tyrosine protein kinase, active site IPR008967 p53-like transcription factor, DNA-binding 0.133003
IPR003599 Immunoglobulin subtype IPR012345 STAT_DNA_bd. 0.101522
IPR003599 Immunoglobulin subtype IPR001217 STAT protein 0.101522
IPR013151 Immunoglobulin. IPR011992 EF-Hand_type. 0.0700765
IPR011009 Protein kinase-like IPR008967 p53-like transcription factor, DNA-binding 0.00476462

The background colour of the table refers to:

  • Blue Domain is only present in KIT
  • Yellow Domain is only present in STAT5A
  • Green Domain is present in both KIT and STAT5A

0.980
Post-translational Modifications

Protein: KIT

PTMResidueReference
Dephosphorylation 570 PubMed, HPRD
N-linked 130 PubMed, HPRD
Phosphorylation 545 PubMed, HPRD
Phosphorylation 547 PubMed, HPRD
Phosphorylation 553 PubMed, HPRD
Phosphorylation 568 PubMed, HPRD
Phosphorylation 570 PubMed, HPRD
Phosphorylation 703 PubMed, HPRD
Phosphorylation 721 PubMed, HPRD
Phosphorylation 730 PubMed, HPRD
Phosphorylation 741 PubMed, HPRD
Phosphorylation 746 PubMed, HPRD
Phosphorylation 747 PubMed, HPRD
Phosphorylation 821 PubMed, HPRD
Phosphorylation 900 PubMed, HPRD
Phosphorylation 936 PubMed, HPRD
Phosphorylation 959 PubMed, HPRD

Protein: STAT5A

PTMResidueReference
Dephosphorylation 694 PubMed, HPRD
Phosphorylation 694 PubMed, HPRD
Phosphorylation 726 PubMed, HPRD
Phosphorylation 780 PubMed, HPRD
Phosphotyrosine 694 PubMed, HPRD
Localisation

Protein: KIT

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD

Protein: STAT5A

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between KIT and STAT5A that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between KIT andSTAT5A. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , KIT has 1344 interactors and STAT5A has 1739 interactors of which there are 822 common interactors.

Common InteractorName of Common InteractorScore for KIT-Interactor (?)Score for STAT5A-Interactor (?)
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 422.00 563.00
CRKL CRKL: Crk-like protein 388.00 430.00
NCK2 NCK2: Cytoplasmic protein NCK2 315.00 0.171
STAT5B STAT5B: Signal transducer and activator of transcription 5B 214.00 409.00
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 127.00 0.586
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 112.00 600.00
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 69.80 16.30
GRAP GRAP: GRB2-related adapter protein 61.50 31.80
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 46.80 1.16E3
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 46.80 250.00
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 43.20 375.00
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 35.00 0.111
JUP JUP, CTNNG, DP3: Junction plakoglobin 15.80 0.035
SHC2 N/A 12.40 3.11
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 11.10 0.032
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 2.08 0.471
LOC392481 N/A 1.07 2.58
SHC4 SHC-transforming protein 4 1.07 2.58
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 1.17
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 0.148
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.165
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.902 1.50
SYK SYK: Tyrosine-protein kinase SYK 0.902 2.17
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.902 2.17
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.902 3.64
STAT3 0.878 12.60
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.878 0.148
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.808 0.275
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.808 0.874
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 0.694
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.808 1.04E3
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.731 0.307
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 1.20
JAK1 0.731 1.78
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.731 0.152
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.731 0.191
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 0.770
CSK CSK: Tyrosine-protein kinase CSK 0.655 2.17
VAV1 VAV1, VAV: Proto-oncogene vav 0.655 0.372
RIN1 RIN1: Ras and Rab interactor 1 0.655 0.111
BMX N/A 0.654 0.775
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 1.35
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.251
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.644 2.42
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.644 0.152
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.644 0.307
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.644 0.775
GRB10 N/A 0.617 0.051
CRK CRK: Proto-oncogene C-crk 0.617 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.051
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 0.775
LYN LYN: Tyrosine-protein kinase Lyn 0.577 1.78
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.577 1.78
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.577 856.00
APS SH2B2, APS: SH2B adapter protein 2 0.577 0.111
HCK N/A 0.577 1.78
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.577 0.088
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.577 0.225
STAT6 STAT6: Signal transducer and activator of transcription 6 0.577 370.00
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.553 0.046
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.520 0.874
STAT2 STAT2: Signal transducer and activator of transcription 2 0.497 0.126
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.483 131.00
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.403 0.274
SOCS2 SOCS2, CIS2, SSI2, STATI2: Suppressor of cytokine signaling 2 0.361 0.028
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.361 0.148
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.065
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.318 0.064
STAT4 STAT4: Signal transducer and activator of transcription 4 0.318 7.69
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.307 0.081
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.275 1.33
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.027
IPO7 IPO7: Uncharacterized protein IPO7 0.202 0.0425
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.200 0.305
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.191 0.072
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.191 0.074
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.065
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.181 0.461
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.181 0.225
VAV3 VAV3: Protein vav-3 0.179 0.036
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.171 0.065
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.171 0.655
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.166 0.191
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.049
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FN1 N/A 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
KIR3DL1 N/A 0.165 0.109
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.878
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
FYN N/A 0.162 0.402
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.152 0.340
ITGAE ITGAE: Integrin alpha-E precursor 0.152 0.027
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.152 0.081
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.152 0.202
EPOR EPOR: Erythropoietin receptor precursor 0.152 0.100
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.152 0.166
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.152 0.065
PTPRZ1 N/A 0.152 0.058
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.152 0.065
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.152 0.0727
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.152 0.152
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.148 0.461
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.878
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.878
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 112.00
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.098
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.098
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.098
BSG N/A 0.148 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.878
ATRN N/A 0.148 0.044
RIN3 N/A 0.145 0.044
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.143 0.050
VPREB1 VPREB1, VPREB: Immunoglobulin iota chain precursor 0.137 0.039
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.136 0.0818
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.127 0.075
GAB2 N/A 0.126 0.191
CD69 CD69: Early activation antigen CD69 0.123 0.027
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.123 0.202
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.123 0.0727
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.072
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.123 0.166
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.081
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.123 0.202
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.123 0.027
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.123 0.581
SORL1 SORL1: Sortilin-related receptor precursor 0.123 0.166
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.123 0.202
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.123 0.166
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.123 0.126
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.100
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.123 0.166
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.123 0.465
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.0727
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.123 0.202
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.123 0.654
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.065
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.123 0.166
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.123 0.202
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.113 0.136
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.113 0.054
STMN1 STMN1, LAP18, OP18: Stathmin 0.113 0.029
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.113 0.171
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.113 0.225
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.111 0.577
DCC DCC: Netrin receptor DCC precursor 0.111 0.064
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.111 0.520
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.111 0.577
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.111 0.586
INSR INSR: Insulin receptor precursor 0.111 277.00
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.111 0.065
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.111 0.064
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.111 0.058
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.113
NF2 NF2, SCH: Merlin 0.109 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.083
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.148
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
PPEF1 N/A 0.109 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.083
PSCD2 N/A 0.109 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.148
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
CGN N/A 0.109 0.049
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.109 0.047
CNN2 CNN2: Calponin-2 0.109 0.165
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.083
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
GHR GHR: Growth hormone receptor precursor 0.109 0.100
PVR PVR, PVS: Poliovirus receptor precursor 0.109 0.0727
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.109 0.065
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.109 0.274
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.081
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.166
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.109 0.081
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.109 0.072
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.109 0.100
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.072
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.109 0.166
LILRB1 N/A 0.109 0.166
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.109 0.202
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.109 0.166
ITGB4 N/A 0.109 0.065
CRLF3 N/A 0.109 0.274
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.202
PRLR PRLR: Prolactin receptor precursor 0.109 0.065
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.126
F3 F3: Tissue factor precursor 0.109 0.065
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.081
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.081
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.519
EGF EGF: Pro-epidermal growth factor precursor 0.109 0.072
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.105 0.036
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.100 0.080
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.100 0.139
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.100 0.123
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.100 0.041
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.100 0.031
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.202
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.098 0.0727
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.098 0.072
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.098 0.065
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.098 0.029
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.202
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.098 0.0727
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.098 0.065
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.126
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.098 0.072
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.098 0.126
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.098 0.072
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.098 0.100
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.098 0.072
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.037
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.098 0.025
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.075
ARHGEF7 N/A 0.098 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
SNX3 N/A 0.098 0.025
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.075
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.148
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.098 0.062
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.047
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.047
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
ELMO1 N/A 0.098 0.148
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.098 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.073
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.097 0.029
NEO1 NEO1, NGN: Neogenin precursor 0.097 0.052
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.577
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.097 0.099
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.097 0.181
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.586
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.097 0.655
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.097 0.520
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.097 0.586
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.097 0.520
TNC TNC, HXB: Tenascin precursor 0.097 0.058
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.097 0.577
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.096 0.126
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.0333
SOS1 SOS1: Son of sevenless homolog 1 0.094 0.148
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.094 0.245
CDK6 CDK6: Cell division protein kinase 6 0.091 0.225
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.091 0.070
CD2AP CD2AP: CD2-associated protein 0.090 0.372
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.090 0.225
THOP1 THOP1: Thimet oligopeptidase 0.090 0.029
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.097
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.111
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.090 0.225
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.090 0.035
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.090 0.097
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.090 0.037
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.090 0.088
DOK1 DOK1: Docking protein 1 0.090 0.372
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.090 0.225
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.090 0.088
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.090 0.171
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.090 0.111
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.090 0.043
RDX RDX: Radixin 0.090 0.111
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.090 0.171
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.088 0.586
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.088 0.065
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.086 0.225
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.086 0.086
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
ATP2A3 ATP2A3: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 0.083 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.109
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.083 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.049
THOC1 THOC1, HPR1: THO complex subunit 1 0.0818 0.188
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.0818 0.046
XPO1 XPO1, CRM1: Exportin-1 0.0818 0.063
GAB1 GAB1: GRB2-associated-binding protein 1 0.081 0.123
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.081 0.136
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.081 0.251
GRLF1 N/A 0.081 0.055
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.081 0.028
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 0.859
IRS1 IRS1: Insulin receptor substrate 1 0.081 0.098
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.081 0.123
SPTAN1 N/A 0.081 0.098
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.081 0.109
S100B S100B: Protein S100-B 0.081 0.049
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.191
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.081 0.171
SNCB SNCB: Beta-synuclein 0.081 0.035
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.081 0.035
CNN3 CNN3: Calponin-3 0.081 0.098
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.063
ROCK1 ROCK1: Rho-associated protein kinase 1 0.081 0.251
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.081 0.123
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.081 0.307
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.0794 0.027
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.077 0.033
FADD FADD, MORT1: Protein FADD 0.077 0.075
ATP2B1 N/A 0.077 0.032
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.075 0.127
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.075 0.188
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.075 0.275
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.075 0.111
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.044
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
JAG2 JAG2: Jagged-2 precursor 0.075 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.098
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.044
MSN MSN: Moesin 0.073 0.275
CHP CHP: Calcium-binding protein p22 0.073 0.054
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.073 0.275
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.073 0.372
PLD2 PLD2: Phospholipase D2 0.073 0.111
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.073 0.139
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.073 0.111
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.073 0.372
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.073 0.225
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.073 0.046
FNBP1 N/A 0.073 0.372
VWF VWF, F8VWF: von Willebrand factor precursor 0.073 0.041
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.073 0.275
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.073 0.088
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.073 0.372
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.073 0.099
TLN1 TLN1: Uncharacterized protein TLN1 0.073 0.225
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.073 0.275
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.073 0.078
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.073 0.099
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.073 0.136
DLG2 DLG2: Disks large homolog 2 0.073 0.041
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.073 0.041
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.073 0.136
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.073 0.035
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.073 0.225
PSD TYL: TYL protein 0.073 0.097
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.072 0.046
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.072 0.045
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.072 0.096
CSPG2 N/A 0.072 0.0794
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.088
VASP VASP: Vasodilator-stimulated phosphoprotein 0.072 0.251
S100A3 S100A3, S100E: Protein S100-A3 0.072 0.049
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.072 0.123
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.045
S100A7 S100A7, PSOR1: Protein S100-A7 0.072 0.049
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.072 0.060
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.072 0.251
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.109
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.072 0.046
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.098
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.072 0.307
TNNC1 TNNC1, TNNC: Troponin C, slow skeletal and cardiac muscles 0.072 0.039
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.148
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.071 0.304
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.069 0.275
CETN1 CETN1, CEN1, CETN: Centrin-1 0.0688 0.036
CDK4 CDK4: Cell division protein kinase 4 0.067 0.275
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.067 0.063
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.067 0.063
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.067 0.136
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.067 0.461
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.067 0.038
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.067 0.225
HSP90AA1 Hsp89-alpha-delta-N 0.067 0.114
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.065 0.077
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.065 0.251
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.065 0.191
MYL3 MYL3: Myosin light polypeptide 3 0.064 0.035
TTN N/A 0.064 0.097
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.111
LCP1 LCP1, PLS2: Plastin-2 0.064 0.372
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.064 0.097
SORBS3 SORBS3, SCAM1: Vinexin 0.064 0.097
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.041
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.064 0.071
PSCD4 PSCD4, CYT4: Cytohesin-4 0.064 0.275
CXorf9 N/A 0.064 0.275
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.064 0.035
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.064 0.275
VIL2 N/A 0.064 0.171
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.064 0.086
GMIP GMIP: GEM-interacting protein 0.064 0.139
DAB2 DAB2, DOC2: Disabled homolog 2 0.064 0.097
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.064 0.037
RASA3 RASA3: Ras GTPase-activating protein 3 0.064 0.136
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.064 0.0308
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.111
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.064 0.041
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.064 0.088
TLN2 TLN2: Uncharacterized protein TLN2 0.064 0.078
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.064 0.0308
DAB1 DAB1: Disabled homolog 1 0.064 0.111
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.064 0.225
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.064 0.037
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.318
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.065
RYR2 RYR2: Ryanodine receptor 2 0.063 0.041
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.063 0.0727
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.062 0.072
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.062 0.075
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.062 0.032
MT3 MT3: Metallothionein-3 0.062 0.110
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.062 0.058
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.098
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.036
PLD1 PLD1: Phospholipase D1 0.058 0.111
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.058 0.099
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.058 0.088
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.058 0.031
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.057 0.148
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.057 0.090
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.057 0.058
FUBP1 N/A 0.057 0.260
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.057 0.275
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.056 0.245
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.056 0.067
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.090
NOTCH4 N/A 0.056 0.029
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.056 0.026
RHO RHO, OPN2: Rhodopsin 0.055 0.029
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.055 0.029
HPN HPN, TMPRSS1: Serine protease hepsin 0.055 0.029
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.055 0.029
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.055 0.032
CD44 N/A 0.055 0.061
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.055 0.029
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.055 0.202
BZRAP1 BZRAP1, KIAA0612, RBP1: Peripheral-type benzodiazepine receptor-associated prote 0.053 0.0308
TBXA2R TBXA2R: Thromboxane A2 receptor 0.052 0.049
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.052 0.0446
DOK2 DOK2: Docking protein 2 0.051 0.051
NCAM1 N/A 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
IGHM N/A 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
MARK2 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
HLA-A N/A 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
UBAP2L N/A 0.051 0.051
IGHD N/A 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.046
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
C9orf88 N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
PTPRA N/A 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
IGHG1 N/A 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
RAPH1 N/A 0.051 0.051
CENTA1 CENTA1: Centaurin-alpha 1 0.051 0.051
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.051 0.065
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.081
PLEK PLEK, P47: Pleckstrin 0.051 0.202
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.051 0.064
ETS2 ETS2: Protein C-ets-2 0.0513 0.126
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.051 0.188
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.051 0.136
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.051 0.275
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.051 0.171
MDN1 MDN1, KIAA0301: Midasin 0.051 0.038
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.051 0.046
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.051 0.372
SYMPK SYMPK, SPK: Symplekin 0.051 0.029
CTPS CTPS: CTP synthase 1 0.051 0.038
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.051 0.032
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.051 0.029
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.051 0.171
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.051 0.461
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.051 0.275
LRFN4 LRFN4: Leucine-rich repeat and fibronectin type-III domain-containing protein 4 0.050 0.032
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.100
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.049 0.100
CCR5 CCR5: CCR5 receptor (Fragment) 0.049 0.166
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.049 0.072
MYO18A 0.049 0.148
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.028
MAPK15 N/A 0.049 0.165
MAP2K5 N/A 0.049 0.165
TSC2 TSC2, TSC4: Tuberin 0.049 0.025
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.028
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.049 0.051
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.049 0.064
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.049 0.026
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.049 0.051
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.049 0.029
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.049 0.029
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.044
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
LMO7 N/A 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.046 0.064
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.046 0.148
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.0453 0.251
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.0453 0.127
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.0453 0.191
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0453 0.416
COBL N/A 0.0453 0.110
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.0453 0.032
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.0453 0.123
WEE1 WEE1: Wee1-like protein kinase 0.0453 0.171
HD HD, IT15: Huntingtin 0.0453 0.052
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.0453 0.155
TP73 TP73, P73: Tumor protein p73 0.045 0.072
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.044 0.073
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.148
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.075
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.148
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
NIPBL N/A 0.044 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.148
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.075
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.025
SEC24B SEC24B: Protein transport protein Sec24B 0.041 0.046
CDK2 CDK2: Cell division protein kinase 2 0.041 0.275
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.041 0.275
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.041 0.111
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.041 0.275
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.041 0.114
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.041 0.046
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.041 0.029
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.041 0.099
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.041 0.139
CDK5 CDK5: Cell division protein kinase 5 0.041 0.136
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.041 0.461
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.041 0.136
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.041 0.372
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.041 112.00
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.041 0.225
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.041 0.041
RPS6KB1 N/A 0.041 0.372
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.041 0.063
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.041 0.372
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.041 0.097
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.041 0.097
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.041 0.035
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.041 0.094
MAGED2 N/A 0.041 0.049
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.041 0.275
FCER1A FCER1A, FCE1A: High affinity immunoglobulin epsilon receptor subunit alpha precu 0.041 0.039
MFAP3 MFAP3: Microfibril-associated glycoprotein 3 precursor 0.041 0.032
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.090
RYR1 0.041 0.037
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.041 0.090
MYH9 MYH9: Myosin-9 0.041 0.181
DSP DSP: Desmoplakin 0.04 0.049
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.083
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
COTL1 COTL1, CLP: Coactosin-like protein 0.04 0.025
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.028
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
MYB MYB: Myb proto-oncogene protein 0.039 0.074
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.065
H1FX H1FX: Histone H1x 0.039 0.124
RAP1GA1 N/A 0.039 0.033
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.039 0.091
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.038 0.030
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.038 0.0782
DBN1 DBN1, D0S117E: Drebrin 0.037 0.026
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.037 0.307
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.037 0.069
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.037 0.077
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.109
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.037 0.152
CFL2 CFL2: Cofilin-2 0.036 0.025
SVIL SVIL: Supervillin 0.036 0.025
GSN GSN: Gelsolin precursor 0.036 0.025
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.035 0.029
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.035 0.026
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.064
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.035 0.029
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.035 0.111
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.035 0.041
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.035 0.090
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.035 0.0818
ANXA3 ANXA3, ANX3: Annexin A3 0.034 0.065
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.034 0.100
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.034 0.042
CNN1 CNN1: Calponin-1 0.0338 0.0338
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.0338 0.030
MAL2 MAL2: Protein MAL2 0.034 0.034
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.033 0.044
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.033 0.188
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.033 0.139
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.033 0.046
B2M B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro 0.033 0.037
STK10 STK10: Uncharacterized protein STK10 0.033 0.275
DYRK3 N/A 0.033 0.097
FLII FLII, FLIL: Protein flightless-1 homolog 0.033 0.046
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.033 0.171
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.033 0.046
KIAA0690 N/A 0.033 0.029
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.033 0.171
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.033 0.111
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.033 0.275
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.033 0.088
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.033 0.088
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.033 0.038
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.097
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.099
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.033 0.088
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.033 0.225
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.033 0.275
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.033 0.275
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.033 0.171
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.033 0.088
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.033 0.111
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.052
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.155
GAS2 GAS2: Growth arrest-specific protein 2 0.032 0.123
PRKAA1 N/A 0.032 0.152
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.032 0.171
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.152
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.032 0.111
FLNA FLNA, FLN, FLN1: Filamin-A 0.032 0.251
STK16 N/A 0.032 0.152
CDKL5 N/A 0.032 0.098
GPR23 LPA4, GPR23, P2RY9: Lysophosphatidic acid receptor 4 0.032 0.037
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.031 0.067
XRCC1 XRCC1: DNA-repair protein XRCC1 0.031 0.091
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.031 0.081
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.0308 0.026
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.0308 0.051
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.0308 0.440
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.0308 0.200
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.034
TNN TNN: Tenascin-N precursor 0.030 0.030
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.053
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.098
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.030 0.044
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.098
SYNGR2 SYNGR2, UNQ352/PRO615: Synaptogyrin-2 0.030 0.030
CCNT2 CCNT2: Cyclin-T2 0.030 0.044
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.030 0.044
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.044
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.098
CREB1 CREB1: cAMP response element-binding protein 0.030 0.044
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.030 0.044
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.030 0.041
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.030 0.037
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.029 0.098
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.029 0.099
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.029 0.171
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.171
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.029 0.049
WASPIP N/A 0.029 0.275
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.029 0.171
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.097
MYO3A MYO3A: Myosin IIIA 0.029 0.088
CDK7 CDK7, MO15: Cell division protein kinase 7 0.029 0.136
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.136
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.029 0.044
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.029 0.111
ATM ATM: Serine-protein kinase ATM 0.029 0.225
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.097
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.029 0.097
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.029 0.088
TSHR N/A 0.029 0.029
KCNJ12 KCNJ12, IRK2, KCNJN1: ATP-sensitive inward rectifier potassium channel 12 0.029 0.026
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
MTM1 MTM1, CG2: Myotubularin 0.029 0.044
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.028 0.049
C3AR1 C3AR1, AZ3B, C3R1, HNFAG09: C3a anaphylatoxin chemotactic receptor 0.028 0.049
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
DRD2 DRD2: D(2) dopamine receptor 0.028 0.049
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.028 0.049
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.028 0.067
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.028 0.032
CCNH CCNH: Cyclin-H 0.028 0.041
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.028 0.111
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.028 0.090
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.028 0.111
AP2M1 AP2M1, CLAPM1, KIAA0109: AP-2 complex subunit mu-1 0.028 0.051
HDLBP HDLBP, HBP, VGL: Vigilin 0.027 0.056
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.027 0.056
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.027 0.188
PMP2 PMP2: Myelin P2 protein 0.027 0.044
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.027 0.049
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
FGFR2 N/A 0.027 0.217
FABP1 FABP1, FABPL: Fatty acid-binding protein, liver 0.0263 0.055
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.0263 0.041
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.0263 0.045
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.0263 0.045
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.171
PARVA PARVA, MXRA2: Alpha-parvin 0.026 0.078
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.026 0.046
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.026 0.088
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.026 47.50
FES N/A 0.0258 0.0258
F2RL1 F2RL1, GPR11, PAR2: Proteinase-activated receptor 2 precursor 0.026 0.037
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.026 0.046
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.026 0.037
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.026 0.171
ADCY3 ADCY3, KIAA0511: Adenylate cyclase type 3 0.026 0.073
ERF ERF: ETS domain-containing transcription factor ERF 0.025 0.0453
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.081
ETV1 ETV1, ER81: ETS translocation variant 1 0.025 0.033
CMTM6 CMTM6, CKLFSF6: CKLF-like MARVEL transmembrane domain-containing protein 6 0.025 0.056
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.126
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.025 0.044
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.036
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.098
FGFR2 N/A 0.025 6.17
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.098
0.572
Total Score 1.11E5