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Evidence of Interaction Between KIT and CRKL

The interaction score between KIT and CRKL is 8.90E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between KIT and CRKL = 0.18

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

2.30E-3
Orthology
OrganismKIT OrthologueCRKL OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00018335 0.132 IPI00013864 0.053
human IPI00021396 0.132 IPI00013864 0.053
human IPI00018335 0.132 IPI00399054 0.438
  • InVitro

Get References From PubMed

human IPI00021396 0.132 IPI00399054 0.438
  • InVitro

Get References From PubMed

worm O76698 0.132 Q9NHC3 0.438
worm Q21038 0.132 Q9NHC3 0.438
worm Q21041 0.132 Q9NHC3 0.438

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

1.07
Domains Domains present in KIT and CRKL:
Domains in KITDomains in CRKL
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.
IPR001452 SH3
IPR000980 SH2 motif
IPR011511 SH3_2.

The Chi square scores for co-occurrence of domains that are present in KIT and CRKL are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR008266 Tyrosine protein kinase, active site IPR001452 SH3 164.706
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR001245 Tyrosine protein kinase IPR001452 SH3 100.857
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR003599 Immunoglobulin subtype IPR000980 SH2 motif 66.4833
IPR003598 Immunoglobulin C-2 type IPR000980 SH2 motif 64.7072
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR013151 Immunoglobulin. IPR000980 SH2 motif 36.9251
IPR001824 Receptor tyrosine kinase, class III IPR001452 SH3 32.2626
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR003598 Immunoglobulin C-2 type IPR001452 SH3 26.0449
IPR003599 Immunoglobulin subtype IPR001452 SH3 22.2905
IPR011009 Protein kinase-like IPR001452 SH3 20.4416
IPR007110 Immunoglobulin-like IPR001452 SH3 20.3228
IPR013151 Immunoglobulin. IPR001452 SH3 14.5395
IPR008266 Tyrosine protein kinase, active site IPR011511 SH3_2. 10.9904
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001452 SH3 8.64336
IPR001245 Tyrosine protein kinase IPR011511 SH3_2. 4.28273
IPR007110 Immunoglobulin-like IPR011511 SH3_2. 0.657737
IPR000719 Protein kinase IPR011511 SH3_2. 0.0847071
IPR003598 Immunoglobulin C-2 type IPR011511 SH3_2. 0.0499293
IPR003599 Immunoglobulin subtype IPR011511 SH3_2. 0.0216579
IPR011009 Protein kinase-like IPR011511 SH3_2. 0.00500251

The background colour of the table refers to:

  • Blue Domain is only present in KIT
  • Yellow Domain is only present in CRKL
  • Green Domain is present in both KIT and CRKL

0.980
Post-translational Modifications

Protein: KIT

PTMResidueReference
Dephosphorylation 570 PubMed, HPRD
N-linked 130 PubMed, HPRD
Phosphorylation 545 PubMed, HPRD
Phosphorylation 547 PubMed, HPRD
Phosphorylation 553 PubMed, HPRD
Phosphorylation 568 PubMed, HPRD
Phosphorylation 570 PubMed, HPRD
Phosphorylation 703 PubMed, HPRD
Phosphorylation 721 PubMed, HPRD
Phosphorylation 730 PubMed, HPRD
Phosphorylation 741 PubMed, HPRD
Phosphorylation 746 PubMed, HPRD
Phosphorylation 747 PubMed, HPRD
Phosphorylation 821 PubMed, HPRD
Phosphorylation 900 PubMed, HPRD
Phosphorylation 936 PubMed, HPRD
Phosphorylation 959 PubMed, HPRD

Protein: CRKL

PTMResidueReference
Phosphorylation 107 PubMed, HPRD
Phosphorylation 207 PubMed, HPRD
Phosphotyrosine 207 HPRD
Phosphotyrosine 251 HPRD
Localisation

Protein: KIT

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD

Protein: CRKL

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between KIT and CRKL that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between KIT andCRKL. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , KIT has 1344 interactors and CRKL has 1611 interactors of which there are 789 common interactors.

Common InteractorName of Common InteractorScore for KIT-Interactor (?)Score for CRKL-Interactor (?)
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 487.00 430.00
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 422.00 1.17
NCK2 NCK2: Cytoplasmic protein NCK2 315.00 108.00
STAT5B STAT5B: Signal transducer and activator of transcription 5B 214.00 0.245
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 127.00 600.00
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 112.00 536.00
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 69.80 7.56
GRAP GRAP: GRB2-related adapter protein 61.50 0.028
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 46.80 388.00
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 46.80 281.00
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 43.20 370.00
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 35.00 65.60
JUP JUP, CTNNG, DP3: Junction plakoglobin 15.80 0.054
SHC2 N/A 12.40 1.29
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 11.10 0.040
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 2.08 0.583
LOC392481 N/A 1.07 1.07
SHC4 SHC-transforming protein 4 1.07 1.07
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 1.17
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 0.148
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.165
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.902 1.98
SYK SYK: Tyrosine-protein kinase SYK 0.902 1.78
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.902 2.94
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.902 2.94
STAT3 0.878 0.148
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.878 0.148
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.808 0.275
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.808 0.874
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 1.07
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.808 1.78
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.731 0.191
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 1.20
JAK1 0.731 1.78
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.731 0.152
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.731 0.251
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 1.07
CSK CSK: Tyrosine-protein kinase CSK 0.655 2.94
VAV1 VAV1, VAV: Proto-oncogene vav 0.655 0.275
RIN1 RIN1: Ras and Rab interactor 1 0.655 0.136
BMX N/A 0.654 0.775
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 1.35
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.191
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.644 1.98
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.644 0.191
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.644 0.191
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.644 0.975
GRB10 N/A 0.617 0.051
CRK CRK: Proto-oncogene C-crk 0.617 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.051
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 0.859
LYN LYN: Tyrosine-protein kinase Lyn 0.577 1.78
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.577 1.35
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.577 1.35
APS SH2B2, APS: SH2B adapter protein 2 0.577 0.136
HCK N/A 0.577 1.07
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.577 0.097
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.577 0.171
STAT6 STAT6: Signal transducer and activator of transcription 6 0.577 132.00
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.553 0.046
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.520 1.07
STAT2 STAT2: Signal transducer and activator of transcription 2 0.497 0.126
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.483 46.90
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.403 0.166
SOCS2 SOCS2, CIS2, SSI2, STATI2: Suppressor of cytokine signaling 2 0.361 0.036
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.361 0.181
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.081
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.318 0.064
STAT4 STAT4: Signal transducer and activator of transcription 4 0.318 0.090
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.307 0.081
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.275 0.808
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.027
IPO7 IPO7: Uncharacterized protein IPO7 0.202 0.052
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.200 0.402
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.191 0.100
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.191 0.036
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.065
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.181 0.372
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.181 0.171
VAV3 VAV3: Protein vav-3 0.179 0.028
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.171 0.065
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.171 0.655
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.166 0.191
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FN1 N/A 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.098
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.098
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
KIR3DL1 N/A 0.165 0.109
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.878
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
FYN N/A 0.162 0.402
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.152 0.274
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.152 0.081
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.152 0.202
EPOR EPOR: Erythropoietin receptor precursor 0.152 0.126
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.152 0.126
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.152 0.0727
PTPRZ1 N/A 0.152 0.064
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.152 0.0727
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.152 0.072
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.152 0.191
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.148 0.275
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.878
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.878
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 0.098
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.098
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.098
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.098
BSG N/A 0.148 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.878
ATRN N/A 0.148 0.044
RIN3 N/A 0.145 0.036
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.143 0.041
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.143 0.028
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.136 0.181
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.127 0.0453
GAB2 N/A 0.126 0.191
CD69 CD69: Early activation antigen CD69 0.123 0.027
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.123 0.202
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.123 0.058
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.081
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.123 0.126
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.126
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.123 0.274
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.123 0.581
SORL1 SORL1: Sortilin-related receptor precursor 0.123 0.148
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.123 0.202
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.123 0.126
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.123 0.126
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.072
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.123 0.166
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.123 0.586
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.0727
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.123 0.166
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.123 0.519
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.081
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.123 0.126
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.123 0.202
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.113 0.171
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.113 0.087
STMN1 STMN1, LAP18, OP18: Stathmin 0.113 0.029
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.113 0.225
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.113 0.372
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.111 0.577
DCC DCC: Netrin receptor DCC precursor 0.111 0.064
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.111 0.577
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.111 0.655
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.111 0.577
INSR INSR: Insulin receptor precursor 0.111 277.00
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.111 0.065
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.111 0.064
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.111 0.064
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.113
NF2 NF2, SCH: Merlin 0.109 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.083
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.148
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
PPEF1 N/A 0.109 0.052
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.052
PSCD2 N/A 0.109 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.148
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.109 0.047
CNN2 CNN2: Calponin-2 0.109 0.148
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.052
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
GHR GHR: Growth hormone receptor precursor 0.109 0.100
PVR PVR, PVS: Poliovirus receptor precursor 0.109 0.065
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.109 0.065
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.109 0.126
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.126
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.166
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.109 0.100
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.109 0.126
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.109 0.126
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.072
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.109 0.126
LILRB1 N/A 0.109 0.126
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.109 0.202
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.109 0.100
ITGB4 N/A 0.109 0.081
CRLF3 N/A 0.109 0.274
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.166
PRLR PRLR: Prolactin receptor precursor 0.109 0.0727
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.126
F3 F3: Tissue factor precursor 0.109 0.072
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.100
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.100
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.581
EGF EGF: Pro-epidermal growth factor precursor 0.109 0.065
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.105 0.0446
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.100 0.233
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.100 0.191
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.100 0.041
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.100 0.031
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.100
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.098 0.065
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.098 0.072
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.098 0.072
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.098 0.065
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.100
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.098 0.0727
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.098 0.081
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.166
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.098 0.065
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.098 0.100
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.098 0.100
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.098 0.081
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.098 0.100
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.126
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.098 0.025
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.148
ARHGEF7 N/A 0.098 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
SNX3 N/A 0.098 0.075
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.148
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.047
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.047
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.047
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.047
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
ELMO1 N/A 0.098 0.148
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.098 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.047
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.113
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.097 0.033
NEO1 NEO1, NGN: Neogenin precursor 0.097 0.065
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.577
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.097 0.078
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.097 0.113
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 250.00
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.097 0.577
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.097 277.00
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.097 0.577
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.097 0.577
TNC TNC, HXB: Tenascin precursor 0.097 0.058
ITGB7 ITGB7: Integrin beta-7 precursor 0.097 0.0818
SFRP1 CDNA FLJ45402 fis, clone BRHIP3029409, moderately similar to Homo sapiens secret 0.097 0.029
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.097 0.655
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.096 0.100
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.0333
SOS1 SOS1: Son of sevenless homolog 1 0.094 0.148
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.094 0.0818
CDK6 CDK6: Cell division protein kinase 6 0.091 0.171
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.091 0.052
CD2AP CD2AP: CD2-associated protein 0.090 0.372
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.090 0.225
THOP1 THOP1: Thimet oligopeptidase 0.090 0.046
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.111
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.097
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.090 0.225
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.090 0.054
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.090 0.111
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.090 0.037
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.090 0.088
DOK1 DOK1: Docking protein 1 0.090 0.225
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.090 0.171
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.090 0.088
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.090 0.171
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.090 0.136
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.090 0.043
RDX RDX: Radixin 0.090 0.171
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.090 0.171
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.088 0.577
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.088 0.058
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.086 0.171
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.086 1.37
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.109
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.109
EDA N/A 0.083 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.109
THOC1 THOC1, HPR1: THO complex subunit 1 0.0818 0.046
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.0818 0.063
XPO1 XPO1, CRM1: Exportin-1 0.0818 0.078
GAB1 GAB1: GRB2-associated-binding protein 1 0.081 0.152
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.081 0.225
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.081 0.103
GRLF1 N/A 0.081 0.062
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.081 0.0308
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 0.859
IRS1 IRS1: Insulin receptor substrate 1 0.081 0.098
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.081 0.191
SPTAN1 N/A 0.081 0.109
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.081 0.109
S100B S100B: Protein S100-B 0.081 0.034
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.123
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.081 0.111
SNCB SNCB: Beta-synuclein 0.081 0.034
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.081 0.031
CNN3 CNN3: Calponin-3 0.081 0.088
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.051
ROCK1 ROCK1: Rho-associated protein kinase 1 0.081 0.251
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.081 0.191
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.081 0.251
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.0794 0.0446
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.077 0.032
FADD FADD, MORT1: Protein FADD 0.077 0.036
ATP2B1 N/A 0.077 0.037
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.075 0.087
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.075 0.046
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.075 0.275
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.075 0.029
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.044
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.098
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.044
MSN MSN: Moesin 0.073 0.275
CHP CHP: Calcium-binding protein p22 0.073 0.054
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.073 0.275
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.073 0.372
PLD2 PLD2: Phospholipase D2 0.073 0.171
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.073 0.225
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.073 0.097
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.073 14.60
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.073 0.114
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.073 0.139
FNBP1 N/A 0.073 10.60
VWF VWF, F8VWF: von Willebrand factor precursor 0.073 0.041
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.073 0.275
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.073 0.088
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.073 14.60
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.073 0.088
TST TST: Thiosulfate sulfurtransferase 0.073 0.035
TLN1 TLN1: Uncharacterized protein TLN1 0.073 0.225
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.073 0.225
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.073 0.099
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.073 0.097
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.073 0.171
DLG2 DLG2: Disks large homolog 2 0.073 0.041
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.073 0.037
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.073 0.225
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.073 0.043
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.073 0.225
PSD TYL: TYL protein 0.073 0.097
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.072 0.045
CSH2 GH1: Somatotropin precursor 0.072 0.025
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.072 0.041
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.072 0.048
CSPG2 N/A 0.072 0.051
CTTN CTTN, EMS1: Src substrate cortactin 0.072 2.77
VASP VASP: Vasodilator-stimulated phosphoprotein 0.072 0.251
S100A3 S100A3, S100E: Protein S100-A3 0.072 0.031
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.072 0.191
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.045
S100A7 S100A7, PSOR1: Protein S100-A7 0.072 0.034
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.072 0.048
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.072 0.251
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.123
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.072 0.041
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.098
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.072 0.307
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.245
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.071 0.304
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.069 0.372
CETN1 CETN1, CEN1, CETN: Centrin-1 0.0688 0.036
CDK4 CDK4: Cell division protein kinase 4 0.067 0.372
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.067 0.063
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.067 0.171
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.067 0.461
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.067 0.063
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.067 0.225
HSP90AA1 Hsp89-alpha-delta-N 0.067 0.063
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.065 0.048
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.065 0.191
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.065 0.191
MYL3 MYL3: Myosin light polypeptide 3 0.064 0.0308
TTN N/A 0.064 0.097
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.111
LCP1 LCP1, PLS2: Plastin-2 0.064 0.118
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.064 5.88
SORBS3 SORBS3, SCAM1: Vinexin 0.064 0.111
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.046
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.064 0.087
PSCD4 PSCD4, CYT4: Cytohesin-4 0.064 0.225
CXorf9 N/A 0.064 0.275
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.064 0.054
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.064 0.275
VIL2 N/A 0.064 0.225
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.064 0.071
GMIP GMIP: GEM-interacting protein 0.064 0.114
DAB2 DAB2, DOC2: Disabled homolog 2 0.064 0.111
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.064 0.046
RASA3 RASA3: Ras GTPase-activating protein 3 0.064 0.171
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.064 0.031
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.064 0.0308
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.035
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.064 0.041
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.064 0.088
TLN2 TLN2: Uncharacterized protein TLN2 0.064 0.088
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.064 0.031
DAB1 DAB1: Disabled homolog 1 0.064 0.136
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.064 0.275
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.064 0.041
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.361
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.065
RYR2 RYR2: Ryanodine receptor 2 0.063 0.025
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.063 0.081
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.062 0.072
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.062 0.032
MT3 MT3: Metallothionein-3 0.062 0.037
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.062 0.065
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.098
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.036
PLD1 PLD1: Phospholipase D1 0.058 0.171
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.058 0.097
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.058 0.111
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.058 0.028
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.057 0.245
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.057 0.181
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.057 0.073
FUBP1 N/A 0.057 0.260
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.057 0.275
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.056 0.148
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.113
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.056 0.029
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.055 0.0453
HPN HPN, TMPRSS1: Serine protease hepsin 0.055 0.029
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.055 0.032
CD44 N/A 0.055 0.061
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.055 0.032
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.055 0.166
DOK2 DOK2: Docking protein 2 0.051 0.051
NCAM1 N/A 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
IGHM N/A 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
MARK2 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
HLA-A N/A 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
UBAP2L N/A 0.051 0.051
IGHD N/A 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.046
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
C9orf88 N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
PTPRA N/A 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
IGHG1 N/A 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
RAPH1 N/A 0.051 0.051
CENTA1 CENTA1: Centaurin-alpha 1 0.051 0.063
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.051 0.081
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.081
PLEK PLEK, P47: Pleckstrin 0.051 0.202
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.051 0.073
ETS2 ETS2: Protein C-ets-2 0.0513 0.100
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.051 0.078
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.051 0.029
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.051 0.225
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.051 0.171
MDN1 MDN1, KIAA0301: Midasin 0.051 0.063
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.051 0.078
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.051 0.461
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.051 0.038
SYMPK SYMPK, SPK: Symplekin 0.051 0.029
CTPS CTPS: CTP synthase 1 0.051 0.063
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.051 0.040
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.051 0.029
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.051 0.225
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.051 0.372
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.051 0.275
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.166
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.049 0.126
CCR5 CCR5: CCR5 receptor (Fragment) 0.049 0.100
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.049 0.081
MYO18A 0.049 0.075
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.028
MAPK15 N/A 0.049 0.165
MAP2K5 N/A 0.049 0.165
TSC2 TSC2, TSC4: Tuberin 0.049 0.025
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.028
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.049 0.051
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.049 0.058
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.049 0.026
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.049 0.051
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.049 0.029
PKD1 PKD1: Polycystin-1 precursor 0.047 0.047
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.098
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 22.10
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
LMO7 N/A 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.046 0.073
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.046 0.090
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.0453 0.251
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.0453 0.127
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.0453 0.416
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0453 0.251
COBL N/A 0.0453 0.098
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.0453 0.032
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.0453 0.123
WEE1 WEE1: Wee1-like protein kinase 0.0453 0.275
HD HD, IT15: Huntingtin 0.0453 0.210
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.0453 0.132
TP73 TP73, P73: Tumor protein p73 0.045 0.081
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.044 0.090
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.148
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.075
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.148
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
NIPBL N/A 0.044 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.148
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.025
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.025
SEC24B SEC24B: Protein transport protein Sec24B 0.041 0.118
CDK2 CDK2: Cell division protein kinase 2 0.041 0.372
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.041 0.233
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.041 0.171
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.041 0.171
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.041 0.129
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.041 0.078
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.041 0.029
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.041 0.097
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.041 0.233
CDK5 CDK5: Cell division protein kinase 5 0.041 0.136
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.041 0.461
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.041 0.171
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.041 0.275
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.041 0.111
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.041 0.461
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.041 0.037
RPS6KB1 N/A 0.041 0.372
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.041 0.063
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.041 0.078
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.041 0.097
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.041 0.097
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.041 0.114
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.041 0.372
MFAP3 MFAP3: Microfibril-associated glycoprotein 3 precursor 0.041 0.039
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.113
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.041 0.181
MYH9 MYH9: Myosin-9 0.041 0.067
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.083
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
COTL1 COTL1, CLP: Coactosin-like protein 0.04 0.025
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.028
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.0263
H1FX H1FX: Histone H1x 0.039 0.027
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.039 0.036
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.038 0.0338
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.038 0.034
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.038 0.059
DBN1 DBN1, D0S117E: Drebrin 0.037 0.026
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.037 0.307
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.037 0.046
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.037 0.026
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.152
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.037 0.152
CFL2 CFL2: Cofilin-2 0.036 0.025
SVIL SVIL: Supervillin 0.036 0.047
GSN GSN: Gelsolin precursor 0.036 0.047
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.035 0.058
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.035 0.064
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.073
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.035 0.064
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.035 0.032
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.035 0.032
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.035 0.040
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.035 0.032
ANXA3 ANXA3, ANX3: Annexin A3 0.034 0.030
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.034 0.046
SDC1 SDC1, SDC: Syndecan-1 precursor 0.034 0.037
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.034 0.053
GJA5 GJA5: Gap junction alpha-5 protein 0.0338 0.047
CNN1 CNN1: Calponin-1 0.0338 0.0273
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.0338 0.0338
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.0338 0.0338
MAL2 MAL2: Protein MAL2 0.034 0.034
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.033 0.044
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.033 0.233
GMFB GMFB: Glia maturation factor beta 0.033 0.029
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.033 0.188
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.033 0.146
B2M B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro 0.033 0.027
STK10 STK10: Uncharacterized protein STK10 0.033 0.275
DYRK3 N/A 0.033 0.097
FLII FLII, FLIL: Protein flightless-1 homolog 0.033 0.071
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.033 0.275
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.033 0.078
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.033 0.275
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.033 0.275
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.033 0.097
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.033 0.097
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.033 0.078
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.088
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.099
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.033 0.111
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.033 0.275
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.033 0.275
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.033 0.372
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.033 0.038
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.033 0.225
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.033 0.136
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.033 0.111
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.052
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.0425
GAS2 GAS2: Growth arrest-specific protein 2 0.032 0.032
PRKAA1 N/A 0.032 0.152
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.032 0.275
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.191
FLNA FLNA, FLN, FLN1: Filamin-A 0.032 0.032
STK16 N/A 0.032 0.251
CDKL5 N/A 0.032 0.098
TOM1L1 TOM1L1, SRCASM: TOM1-like protein 1 0.031 0.030
XRCC1 XRCC1: DNA-repair protein XRCC1 0.031 0.036
NPM1 NPM1, NPM: Nucleophosmin 0.031 0.040
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.031 0.037
SDC4 SDC4: Syndecan-4 precursor 0.0308 0.026
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.0308 0.058
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.0308 0.440
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.0308 0.162
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.034
TNN TNN: Tenascin-N precursor 0.030 0.034
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.034
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.098
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.098
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.036
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.098
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.030 0.036
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.030 0.058
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.029 0.123
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.029 0.088
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.029 0.111
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.275
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.029 0.069
WASPIP N/A 0.029 14.60
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.029 0.225
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.111
MYO3A MYO3A: Myosin IIIA 0.029 0.088
CDK7 CDK7, MO15: Cell division protein kinase 7 0.029 0.275
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.171
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.029 0.049
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.029 0.097
ATM ATM: Serine-protein kinase ATM 0.029 0.225
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.111
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.029 0.111
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.029 0.099
TSHR N/A 0.029 0.029
DLG1 N/A 0.029 0.038
KCNJ12 KCNJ12, IRK2, KCNJN1: ATP-sensitive inward rectifier potassium channel 12 0.029 0.073
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
MTM1 MTM1, CG2: Myotubularin 0.029 0.028
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.028 0.032
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.028 0.040
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.028 0.040
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.028 0.067
HDLBP HDLBP, HBP, VGL: Vigilin 0.027 0.086
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.027 0.069
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.027 0.233
PMP2 PMP2: Myelin P2 protein 0.027 0.044
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.027 0.086
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
FGFR2 N/A 0.027 0.217
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.0263 0.041
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.0263 0.051
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.0263 0.051
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.225
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.026 0.035
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.026 0.097
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.026 0.099
FES N/A 0.0258 0.0258
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.026 0.0453
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.026 0.032
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.026 0.275
TFRC TFRC: Transferrin receptor protein 1 0.026 0.036
ADCY3 ADCY3, KIAA0511: Adenylate cyclase type 3 0.026 0.051
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.065
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.126
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.044
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.098
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.044
0.572
Total Score 8.90E4