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Evidence of Interaction Between JAK2 and INSR

The interaction score between JAK2 and INSR is 6.35E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between JAK2 and INSR = -0.04

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology
OrganismJAK2 OrthologueINSR OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00022353 0.245 IPI00027232 0.438
human IPI00219418 0.385 IPI00027232 0.438
human IPI00011633 0.316 IPI00027232 0.438
  • Other
  • pullDown
  • InVitro
  • InVivo

Get References From PubMed
fly Q24592 1 P09208 0.377

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 1.07
Domains Domains present in JAK2 and INSR:
Domains in JAK2Domains in INSR
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR000299 Band 4.1
IPR000980 SH2 motif
IPR009127 Janus kinase, JAK
IPR009129 Janus kinase 2, JAK2
IPR000494 Epidermal growth-factor receptor (EGFR), L domain
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR006211 Furin-like cysteine rich region
IPR006212 Furin-like repeat
IPR008266 Tyrosine protein kinase, active site
IPR003961 Fibronectin, type III
IPR002011 Receptor tyrosine kinase, class II

The Chi square scores for co-occurrence of domains that are present in JAK2 and INSR are listed below.

Domain 1Domain 2Chi Square
IPR000980 SH2 motif IPR008266 Tyrosine protein kinase, active site 383.26
IPR000980 SH2 motif IPR001245 Tyrosine protein kinase 238.73
IPR000980 SH2 motif IPR003961 Fibronectin, type III 184.508
IPR000980 SH2 motif IPR000719 Protein kinase 82.1364
IPR000980 SH2 motif IPR006211 Furin-like cysteine rich region 46.2087
IPR000980 SH2 motif IPR000494 Epidermal growth-factor receptor (EGFR), L domain 46.2087
IPR000980 SH2 motif IPR006212 Furin-like repeat 43.075
IPR009127 Janus kinase, JAK IPR003961 Fibronectin, type III 39.5737
IPR000719 Protein kinase IPR000719 Protein kinase 30.6895
IPR000980 SH2 motif IPR002011 Receptor tyrosine kinase, class II 24.6768
IPR008266 Tyrosine protein kinase, active site IPR003961 Fibronectin, type III 22.1621
IPR000299 Band 4.1 IPR003961 Fibronectin, type III 15.6566
IPR009127 Janus kinase, JAK IPR008266 Tyrosine protein kinase, active site 13.6237
IPR000299 Band 4.1 IPR008266 Tyrosine protein kinase, active site 12.4084
IPR009129 Janus kinase 2, JAK2 IPR003961 Fibronectin, type III 10.7554
IPR008266 Tyrosine protein kinase, active site IPR008266 Tyrosine protein kinase, active site 9.50479
IPR000719 Protein kinase IPR008266 Tyrosine protein kinase, active site 6.98997
IPR001245 Tyrosine protein kinase IPR003961 Fibronectin, type III 6.5864
IPR009127 Janus kinase, JAK IPR001245 Tyrosine protein kinase 6.21902
IPR000299 Band 4.1 IPR001245 Tyrosine protein kinase 5.02954
IPR011009 Protein kinase-like IPR000719 Protein kinase 2.94434
IPR009129 Janus kinase 2, JAK2 IPR008266 Tyrosine protein kinase, active site 2.50604
IPR000719 Protein kinase IPR001245 Tyrosine protein kinase 2.31134
IPR000719 Protein kinase IPR006212 Furin-like repeat 1.94477
IPR000719 Protein kinase IPR006211 Furin-like cysteine rich region 1.5062
IPR000719 Protein kinase IPR000494 Epidermal growth-factor receptor (EGFR), L domain 1.5062
IPR000719 Protein kinase IPR002011 Receptor tyrosine kinase, class II 1.16654
IPR001245 Tyrosine protein kinase IPR008266 Tyrosine protein kinase, active site 0.959759
IPR009129 Janus kinase 2, JAK2 IPR001245 Tyrosine protein kinase 0.81975
IPR000719 Protein kinase IPR003961 Fibronectin, type III 0.712801
IPR011009 Protein kinase-like IPR003961 Fibronectin, type III 0.616354
IPR001245 Tyrosine protein kinase IPR002011 Receptor tyrosine kinase, class II 0.432179
IPR011009 Protein kinase-like IPR002011 Receptor tyrosine kinase, class II 0.315004
IPR008266 Tyrosine protein kinase, active site IPR000494 Epidermal growth-factor receptor (EGFR), L domain 0.214051
IPR008266 Tyrosine protein kinase, active site IPR006211 Furin-like cysteine rich region 0.214051
IPR009127 Janus kinase, JAK IPR000719 Protein kinase 0.204109
IPR011009 Protein kinase-like IPR006212 Furin-like repeat 0.180255
IPR011009 Protein kinase-like IPR001245 Tyrosine protein kinase 0.178275
IPR000299 Band 4.1 IPR000719 Protein kinase 0.128068
IPR008266 Tyrosine protein kinase, active site IPR006212 Furin-like repeat 0.113534
IPR011009 Protein kinase-like IPR006211 Furin-like cysteine rich region 0.0778402
IPR011009 Protein kinase-like IPR000494 Epidermal growth-factor receptor (EGFR), L domain 0.0778402
IPR001245 Tyrosine protein kinase IPR001245 Tyrosine protein kinase 0.0451828
IPR009129 Janus kinase 2, JAK2 IPR000719 Protein kinase 0.0312904
IPR008266 Tyrosine protein kinase, active site IPR002011 Receptor tyrosine kinase, class II 0.0235657
IPR001245 Tyrosine protein kinase IPR006212 Furin-like repeat 0.00835708
IPR011009 Protein kinase-like IPR008266 Tyrosine protein kinase, active site 0.00724826
IPR000299 Band 4.1 IPR006212 Furin-like repeat 0.00115215
IPR001245 Tyrosine protein kinase IPR000494 Epidermal growth-factor receptor (EGFR), L domain 0.000919029
IPR001245 Tyrosine protein kinase IPR006211 Furin-like cysteine rich region 0.000919029
IPR000299 Band 4.1 IPR000494 Epidermal growth-factor receptor (EGFR), L domain 0.000668742
IPR000299 Band 4.1 IPR006211 Furin-like cysteine rich region 0.000668742

The background colour of the table refers to:

  • Blue Domain is only present in JAK2
  • Yellow Domain is only present in INSR
  • Green Domain is present in both JAK2 and INSR

 0.980
Post-translational Modifications

Protein: JAK2

PTMResidueReference
Dephosphorylation 1007 PubMed, HPRD
Dephosphorylation 1008 PubMed, HPRD
Phosphorylation 201 PubMed, HPRD
Phosphorylation 221 PubMed, HPRD
Phosphorylation 570 PubMed, HPRD
Phosphorylation 813 PubMed, HPRD
Phosphorylation 1007 PubMed, HPRD
Phosphorylation 1008 PubMed, HPRD

Protein: INSR

PTMResidueReference
Dephosphorylation 999 PubMed, HPRD
Dephosphorylation 1185 PubMed, HPRD
Dephosphorylation 1189 PubMed, HPRD
Dephosphorylation 1190 PubMed, HPRD
Glycosylation 43 PubMed, HPRD
Glycosylation 52 PubMed, HPRD
Glycosylation 105 PubMed, HPRD
Glycosylation 138 PubMed, HPRD
Glycosylation 424 PubMed, HPRD
Glycosylation 445 PubMed, HPRD
Glycosylation 769 PubMed, HPRD
Glycosylation 782 PubMed, HPRD
Glycosylation 920 PubMed, HPRD
Glycosylation 933 PubMed, HPRD
N-linked 541 PubMed, HPRD
Phosphorylation 992 PubMed, HPRD
Phosphorylation 999 PubMed, HPRD
Phosphorylation 1062 PubMed, HPRD
Phosphorylation 1064 PubMed, HPRD
Phosphorylation 1185 PubMed, HPRD
Phosphorylation 1189 PubMed, HPRD
Phosphorylation 1190 PubMed, HPRD
Phosphorylation 1314 PubMed, HPRD
Phosphorylation 1332 PubMed, HPRD
Phosphorylation 1333 PubMed, HPRD
Phosphorylation 1348 PubMed, HPRD
Phosphorylation 1354 PubMed, HPRD
Phosphorylation 1355 PubMed, HPRD
Phosphorylation 1361 PubMed, HPRD
Phosphorylation 1362 PubMed, HPRD
Phosphorylation 1375 PubMed, HPRD
Phosphotyrosine 992 PubMed, HPRD
Phosphotyrosine 999 PubMed, HPRD
Phosphotyrosine 1011 PubMed, HPRD
Phosphotyrosine 1185 PubMed, HPRD
Phosphotyrosine 1189 PubMed, HPRD
Phosphotyrosine 1190 PubMed, HPRD
Phosphotyrosine 1355 PubMed, HPRD
Phosphotyrosine 1361 PubMed, HPRD
Localisation

Protein: JAK2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: INSR

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Transitive Score

The common interactors between JAK2 and INSR that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between JAK2 andINSR. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , JAK2 has 1724 interactors and INSR has 1177 interactors of which there are 838 common interactors.

Common InteractorName of Common InteractorScore for JAK2-Interactor (?)Score for INSR-Interactor (?)
STAT6 STAT6: Signal transducer and activator of transcription 6 2.90E3 0.577
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 1.06E3 0.171
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 1.04E3 277.00
STAT5B STAT5B: Signal transducer and activator of transcription 5B 784.00 173.00
ZAP70 ZAP70: Uncharacterized protein ZAP70 650.00 0.520
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 563.00 0.878
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 422.00 0.483
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 370.00 0.577
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 333.00 0.064
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 250.00 0.136
STAM2 STAM2: Signal transducing adapter molecule 2 82.20 0.073
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 53.10 0.029
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 46.90 71.20
LYN LYN: Tyrosine-protein kinase Lyn 6.73 0.577
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 6.03 0.577
HCK N/A 6.03 0.577
SYK SYK: Tyrosine-protein kinase SYK 6.03 0.577
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 6.03 0.577
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 4.07 0.644
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 3.64 0.577
VAV1 VAV1, VAV: Proto-oncogene vav 3.64 0.520
SLA SLA, SLAP, SLAP1: SRC-like-adapter 3.28 0.581
JAK1 2.94 0.520
CSK CSK: Tyrosine-protein kinase CSK 2.94 0.520
LCP2 LCP2: Lymphocyte cytosolic protein 2 2.46 0.320
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 2.17 0.586
BLNK BLNK, BASH, SLP65: B-cell linker protein 1.98 0.644
CRKL CRKL: Crk-like protein 1.78 277.00
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 1.50 0.731
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 1.50 0.731
STAT2 STAT2: Signal transducer and activator of transcription 2 1.48 0.403
FLT3 FLT3, STK1: FL cytokine receptor precursor 1.48 0.111
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 1.35 0.655
NCK2 NCK2: Cytoplasmic protein NCK2 1.35 0.520
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 1.33 0.318
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 1.30 0.980
LNK SH2B3, LNK: SH2B adapter protein 3 1.30 0.980
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 1.30 0.980
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 1.30 0.980
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 1.30 0.980
STAT3 1.30 0.878
RIN3 N/A 1.22 0.128
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 1.20 0.581
LILRB1 N/A 1.19 0.109
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 1.17 0.878
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 1.17 0.098
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 1.17 0.878
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 1.17 0.878
TXK TXK, PTK4: Tyrosine-protein kinase TXK 1.07 0.577
RIN1 RIN1: Ras and Rab interactor 1 1.07 0.577
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 1.07 0.520
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.980 0.165
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.980 0.165
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.980 0.165
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.975 0.581
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.975 0.644
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.975 0.644
STAT4 STAT4: Signal transducer and activator of transcription 4 0.902 0.286
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.878 0.148
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.878 0.148
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.878 0.148
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.878 0.148
APS SH2B2, APS: SH2B adapter protein 2 0.874 0.577
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.872 0.644
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.859 0.072
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.859 0.644
BMX N/A 0.859 0.902
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.852 0.072
KIT KIT: Mast/stem cell growth factor receptor precursor 0.808 0.111
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.781 388.00
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.775 0.577
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.770 0.577
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.763 0.064
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.763 0.064
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.763 0.064
GMIP GMIP: GEM-interacting protein 0.763 0.064
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.763 0.058
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.763 0.064
PSCD4 PSCD4, CYT4: Cytohesin-4 0.763 0.064
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.655 0.088
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.655 0.318
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.654 0.097
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.654 0.191
GRB10 N/A 0.617 0.617
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.617 0.051
CRK CRK: Proto-oncogene C-crk 0.617 0.617
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.617 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.617
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.617
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.617 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.617 0.051
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.586 0.111
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.586 0.111
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.586 0.111
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.586 0.097
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.586 0.111
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.586 0.088
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.581 0.191
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.581 0.355
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.577 0.097
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.577 0.097
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.577 0.097
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.577 0.136
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.561 0.123
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.561 0.109
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.561 0.098
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.553 0.553
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.553 0.046
FLT4 VEGFR3 long form 0.553 0.046
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.520 0.171
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.520 0.111
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.520 0.111
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.520 0.171
MET MET: Hepatocyte growth factor receptor precursor 0.519 0.123
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.515 0.072
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.515 0.065
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.515 0.072
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.515 0.072
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.503 0.046
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.503 0.046
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.503 0.049
FYN N/A 0.491 0.129
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.483 0.098
MSN MSN: Moesin 0.461 0.058
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.461 0.064
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.461 0.029
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.461 0.058
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.461 0.064
LCP1 LCP1, PLS2: Plastin-2 0.461 0.064
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.461 0.064
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.461 0.026
DOK1 DOK1: Docking protein 1 0.461 0.058
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.461 0.064
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.461 0.058
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.416 0.065
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.416 0.072
ROCK1 ROCK1: Rho-associated protein kinase 1 0.416 0.065
GAB2 N/A 0.416 0.081
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.416 0.072
IRS2 IRS2: Insulin receptor substrate 2 0.416 0.100
VASP VASP: Vasodilator-stimulated phosphoprotein 0.416 0.072
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.372 0.058
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.372 0.064
WASPIP N/A 0.372 0.026
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.372 0.058
CXorf9 N/A 0.372 0.058
RPS6KB1 N/A 0.372 0.064
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.372 0.064
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.372 0.058
ALK ALK: ALK tyrosine kinase receptor precursor 0.361 0.064
VAV3 VAV3: Protein vav-3 0.360 0.179
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.347 0.902
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.340 0.098
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.340 0.109
PLEK PLEK, P47: Pleckstrin 0.340 0.045
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.340 0.109
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.340 0.098
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.340 0.098
CRLF3 N/A 0.340 0.098
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.340 0.109
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.340 0.098
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.307 0.081
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.307 0.065
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.305 0.129
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.304 0.026
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.304 0.041
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.275 0.058
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.275 0.064
FNBP1 N/A 0.275 0.064
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.275 0.064
TLN1 TLN1: Uncharacterized protein TLN1 0.275 0.073
CD2AP CD2AP: CD2-associated protein 0.275 0.064
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.275 0.064
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.275 0.064
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.275 0.064
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.275 0.065
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.275 0.064
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.274 0.098
SORL1 SORL1: Sortilin-related receptor precursor 0.274 0.098
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.274 0.109
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.274 0.109
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.274 0.123
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.265 0.038
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.265 0.217
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.265 0.217
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.265 0.217
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.265 0.217
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.253 0.109
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.251 0.072
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.251 0.072
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.251 0.032
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.244 0.129
ATM ATM: Serine-protein kinase ATM 0.225 0.026
CHP CHP: Calcium-binding protein p22 0.225 0.064
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.225 0.064
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.225 0.064
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.225 0.064
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.225 0.073
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.225 0.058
GRAP GRAP: GRB2-related adapter protein 0.218 61.50
FGFR2 N/A 0.217 0.027
CSPG2 N/A 0.214 0.081
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.032
CCR5 CCR5: CCR5 receptor (Fragment) 0.202 0.049
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.202 0.098
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.202 0.045
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.202 0.109
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.202 0.109
GAB1 GAB1: GRB2-associated-binding protein 1 0.191 0.081
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.191 0.065
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.191 0.081
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.191 0.081
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.065
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.191 0.054
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.188 0.029
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.188 0.027
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.185 0.056
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.177 0.128
SOCS2 SOCS2, CIS2, SSI2, STATI2: Suppressor of cytokine signaling 2 0.177 0.145
GRB7 GRB7: Growth factor receptor-bound protein 7 0.176 0.200
SOCS5 SOCS5, CIS6, CISH5, CISH6, KIAA0671: Suppressor of cytokine signaling 5 0.174 0.143
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.171 0.058
SH3BP5 N/A 0.171 0.090
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.171 0.090
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.171 0.058
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.171 0.058
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.171 0.065
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.171 0.113
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.171 0.058
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.064
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.171 0.064
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.166 0.041
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.166 0.049
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.166 0.098
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.109
CNN2 CNN2: Calponin-2 0.165 0.109
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.165 0.109
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.165 0.098
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.109
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.165 0.098
PPEF1 N/A 0.165 0.109
NF2 NF2, SCH: Merlin 0.165 0.109
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.049
MAP2K5 N/A 0.165 0.049
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.165 0.098
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.165 0.109
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.109
EEF2K EEF2K: Elongation factor 2 kinase 0.165 0.098
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.165 0.098
PSCD2 N/A 0.165 0.109
AMPH AMPH, AMPH1: Amphiphysin 0.165 0.109
MAPK15 N/A 0.165 0.109
S100A16 S100A16, AAG13: Protein S100-A16 0.165 0.109
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.109
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.049
GRB14 GRB14: Growth factor receptor-bound protein 14 0.157 0.162
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 0.156 61.50
CHN2 CHN2, ARHGAP3, BCH: Beta-chimaerin 0.156 0.128
FGL2 FGL2: Fibroleukin precursor 0.156 0.064
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.155 0.064
FUBP1 N/A 0.155 0.032
CD44 N/A 0.153 0.055
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.152 0.065
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.152 0.072
STK16 N/A 0.152 0.065
ITGB7 ITGB7: Integrin beta-7 precursor 0.148 0.049
SOS1 SOS1: Son of sevenless homolog 1 0.148 0.037
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.148 0.114
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.098
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.098
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.148 0.098
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.148 0.098
ACTN4 ACTN4: Alpha-actinin-4 0.148 0.098
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.148 0.098
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.098
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.148 0.098
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.148 0.098
ELMO1 N/A 0.148 0.098
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.098
ARHGEF7 N/A 0.148 0.098
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.148 0.098
SNX3 N/A 0.148 0.098
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.098
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.098
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.148 46.90
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.098
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.098
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.098
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.098
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.148 0.098
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.098
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.148 0.025
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.098
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.098
CDC37 CDC37: Hsp90 co-chaperone Cdc37 0.143 0.0273
CHN1 CHN1, ARHGAP2, CHN: N-chimaerin 0.141 0.115
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.026
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.139 0.029
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.139 0.029
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.137 0.056
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.136 0.064
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.136 0.058
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.136 0.064
RASA3 RASA3: Ras GTPase-activating protein 3 0.136 0.058
VIL2 N/A 0.136 0.090
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.136 0.064
PLD2 PLD2: Phospholipase D2 0.136 0.073
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.136 0.065
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.126 0.109
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.126 0.152
CD7 CD7: T-cell antigen CD7 precursor 0.126 0.098
ETS2 ETS2: Protein C-ets-2 0.126 0.025
EPOR EPOR: Erythropoietin receptor precursor 0.126 0.123
SHB SHB: SH2 domain-containing adapter protein B 0.126 0.145
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.125 0.039
ITGAE ITGAE: Integrin alpha-E precursor 0.124 0.056
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.081
TST TST: Thiosulfate sulfurtransferase 0.123 0.064
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.123 0.090
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.123 0.109
FLII FLII, FLIL: Protein flightless-1 homolog 0.118 0.026
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.116 0.030
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.114 0.064
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.114 0.026
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.114 0.029
HSP90AA1 Hsp89-alpha-delta-N 0.114 0.064
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.114 0.029
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.113 0.037
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.113 0.041
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.111 0.049
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.111 0.064
RDX RDX: Radixin 0.111 0.073
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 0.073
ACTN1 ACTN1: Alpha-actinin-1 0.111 0.058
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.111 0.058
COBL N/A 0.110 0.032
SPTAN1 N/A 0.110 0.065
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.110 0.029
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.110 0.041
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.109 0.165
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.109 0.165
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.109 0.165
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.109 0.165
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.109 0.165
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.109 0.165
KIR3DL1 N/A 0.109 0.165
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.165
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.109 0.165
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.109 0.165
FN1 N/A 0.109 0.165
NULL A1BG: Alpha-1B-glycoprotein precursor 0.109 0.165
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.109 0.165
NSBP1 NSBP1: Nucleosome-binding protein 1 0.109 0.0688
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.109 0.165
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.109 0.083
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.109 0.165
LAT LAT: Linker for activation of T-cells family member 1 0.109 0.083
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.109 0.165
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.165
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.109 0.165
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.109 0.165
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.109 0.165
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.109 0.165
DRD2 DRD2: D(2) dopamine receptor 0.109 0.028
S100A7 S100A7, PSOR1: Protein S100-A7 0.109 0.072
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.109 0.072
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.081
IRS1 IRS1: Insulin receptor substrate 1 0.109 0.081
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.109 0.032
TNNC1 TNNC1, TNNC: Troponin C, slow skeletal and cardiac muscles 0.109 0.072
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.100 0.049
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.100 0.098
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.100 0.098
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.100 0.123
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.100 0.051
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.100 0.123
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.100 0.109
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.100 0.037
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.099 15.80
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.099 0.064
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.099 0.097
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.099 0.073
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.099 0.073
TLN2 TLN2: Uncharacterized protein TLN2 0.099 0.064
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.099 0.064
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.099 0.064
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.099 0.058
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.098 0.072
SNCB SNCB: Beta-synuclein 0.098 0.065
S100B S100B: Protein S100-B 0.098 0.072
GRLF1 N/A 0.098 0.065
MCF2 MCF2, DBL: Proto-oncogene DBL 0.098 0.072
MT3 MT3: Metallothionein-3 0.098 0.049
S100A3 S100A3, S100E: Protein S100-A3 0.098 0.081
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.098 0.072
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.098 0.062
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.098 0.148
CNTN1 CNTN1: Contactin-1 precursor 0.098 0.148
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.148
BSG N/A 0.098 0.148
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.098 0.025
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.098 0.062
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.098 0.030
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.098 0.148
CNTN4 CNTN4: Contactin-4 precursor 0.098 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.098 0.062
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.098 0.030
CETN1 CETN1, CEN1, CETN: Centrin-1 0.098 0.062
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.148
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.098 0.062
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.181
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.097 0.044
PSD TYL: TYL protein 0.097 0.058
TTN N/A 0.097 0.064
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.097 0.029
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.097 0.073
STMN1 STMN1, LAP18, OP18: Stathmin 0.097 0.058
SORBS3 SORBS3, SCAM1: Vinexin 0.097 0.064
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.097 0.064
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.097 0.029
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.097 0.058
MYL3 MYL3: Myosin light polypeptide 3 0.097 0.064
DAB1 DAB1: Disabled homolog 1 0.097 0.073
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.097 0.058
PLD1 PLD1: Phospholipase D1 0.097 0.090
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.097 0.058
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0971 0.0263
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.091 0.077
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.091 0.062
TLR4 TLR4: Toll-like receptor 4 precursor 0.090 0.056
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.090 0.037
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.088 0.026
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.088 0.033
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.088 0.073
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.088 0.064
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.088 0.064
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.088 0.064
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.088 0.058
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.088 0.029
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.088 0.064
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.088 0.073
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.088 0.058
CTTN CTTN, EMS1: Src substrate cortactin 0.088 0.100
CNN3 CNN3: Calponin-3 0.088 0.126
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.087 0.032
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.087 0.096
MDN1 MDN1, KIAA0301: Midasin 0.086 0.026
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.086 0.026
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.049
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.083 0.04
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.049
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.04
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.081 0.098
GPA33 GPA33: Cell surface A33 antigen precursor 0.081 0.109
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.081 0.049
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.081 0.098
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.081 0.098
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.081 0.109
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.081 0.123
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.081 0.098
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.081 0.098
IL9R IL9R: Interleukin-9 receptor precursor 0.081 0.098
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.081 0.109
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.081 0.123
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.081 0.098
CENTA1 CENTA1: Centaurin-alpha 1 0.0794 0.041
F5 F5: Coagulation factor V precursor 0.0794 0.100
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.0794 0.072
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.078 0.064
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.078 0.064
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.078 0.058
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 12.50
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.077 0.032
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.077 0.072
TSC2 TSC2, TSC4: Tuberin 0.075 0.044
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.075 0.044
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.044
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.075 0.044
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.074 0.039
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.074 0.049
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.073 0.097
DCC DCC: Netrin receptor DCC precursor 0.073 0.097
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.073 0.041
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.073 0.069
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.073 0.041
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.0727 0.123
PVR PVR, PVS: Poliovirus receptor precursor 0.0727 0.109
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.0727 0.098
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.0727 0.123
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.0727 0.152
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.0727 0.109
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.072 0.063
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.072 0.109
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.072 0.109
EGF EGF: Pro-epidermal growth factor precursor 0.072 0.123
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.123
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.072 0.123
TP73 TP73, P73: Tumor protein p73 0.072 0.063
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.072 0.109
GHR GHR: Growth hormone receptor precursor 0.072 0.123
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.072 0.109
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.072 0.098
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.070 0.053
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.069 0.029
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.069 0.033
CTPS CTPS: CTP synthase 1 0.069 0.029
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.069 0.029
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.0688 0.109
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.0688 0.109
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.067 0.044
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.065 0.088
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.065 0.097
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.065 0.109
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.065 0.123
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.065 0.307
TOM1L1 TOM1L1, SRCASM: TOM1-like protein 1 0.065 0.025
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.065 0.109
F3 F3: Tissue factor precursor 0.065 0.123
ITGB4 N/A 0.065 0.123
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.065 0.041
SCML2 SCML2: Sex comb on midleg-like protein 2 0.065 0.025
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.065 0.127
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.065 0.109
PRLR PRLR: Prolactin receptor precursor 0.065 0.152
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.065 0.063
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.065 0.123
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.065 0.055
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.065 0.098
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.065 0.191
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.064 0.097
TNC TNC, HXB: Tenascin precursor 0.064 0.097
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.064 0.088
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.064 0.111
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.064 0.035
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.064 0.041
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.136
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.063 0.072
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.063 0.029
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.062 0.026
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.062 0.033
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.062 0.029
SPOCK1 SPOCK1, SPOCK, TIC1, TICN1: Testican-1 precursor 0.062 0.098
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.062 0.098
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.062 0.098
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.058 0.037
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.058 0.136
PTPRZ1 N/A 0.058 0.088
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.058 0.152
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.057 0.109
FADD FADD, MORT1: Protein FADD 0.057 0.055
CD69 CD69: Early activation antigen CD69 0.057 0.049
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.056 0.064
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.056 0.033
HDLBP HDLBP, HBP, VGL: Vigilin 0.056 0.033
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.055 0.029
FABP1 FABP1, FABPL: Fatty acid-binding protein, liver 0.055 0.037
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.053 0.0273
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.052 0.049
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.032
NULL Ig lambda chain V-II region NEI 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
IGHD N/A 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
IGHG1 N/A 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
HLA-A N/A 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
KIAA1688 KIAA1688: KIAA1688 protein (Fragment) 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
SPARCL1 SPARCL1: SPARC-like protein 1 precursor 0.051 0.051
IGHM N/A 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
C9orf88 N/A 0.051 0.051
NCAM1 N/A 0.051 0.051
SNX2 SNX2, TRG9: Sorting nexin-2 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
MT1H N/A 0.051 0.051
PTPRA N/A 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
SNX12 N/A 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
SPOCK3 SPOCK3, TICN3, UNQ409/PRO771: Testican-3 precursor 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
RAPH1 N/A 0.051 0.051
PPP1R1B PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
MARK2 N/A 0.051 0.051
IGHA1 N/A 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
UBAP2L N/A 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
ITIH3 ITIH3: Inter-alpha-trypsin inhibitor heavy chain H3 precursor 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
PPP1R14C PPP1R14C, KEPI: Protein phosphatase 1 regulatory subunit 14C 0.051 0.051
IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 0.051 0.072
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.051 0.081
ASGR1 ASGR1: Asialoglycoprotein receptor 1 0.051 0.049
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.040
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.049 0.032
C3AR1 C3AR1, AZ3B, C3R1, HNFAG09: C3a anaphylatoxin chemotactic receptor 0.049 0.028
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.049 0.083
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.049 0.052
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.049 0.028
ATP2A3 ATP2A3: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 0.049 0.083
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.049 0.083
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.049 0.028
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.083
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.049 0.083
TBXA2R TBXA2R: Thromboxane A2 receptor 0.049 0.028
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.049 0.083
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.049 0.028
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.049 0.033
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.049 0.029
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.048 0.029
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.034
COTL1 COTL1, CLP: Coactosin-like protein 0.047 0.036
CFL2 CFL2: Cofilin-2 0.047 0.036
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.047 0.044
SVIL SVIL: Supervillin 0.047 0.036
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.047 0.044
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.047 0.036
GSN GSN: Gelsolin precursor 0.047 0.036
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.046 0.029
NEO1 NEO1, NGN: Neogenin precursor 0.046 0.088
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.046 0.034
PPP1R14A PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.046 0.046
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
EHD3 EHD3, EHD2, PAST3: EH domain-containing protein 3 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
MLLT4 N/A 0.046 0.046
NF1 NF1: Neurofibromin 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
LMO7 N/A 0.046 0.046
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.046 0.060
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.046 0.073
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.046 0.064
NDP NDP: Norrin precursor 0.046 0.081
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.046 0.072
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.046 0.032
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.046 0.091
INHA INHA: Inhibin alpha chain precursor 0.046 0.100
B2M B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro 0.046 0.029
ATP2B1 N/A 0.0453 0.049
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.045 0.091
FSHB FSHB: Follitropin subunit beta precursor 0.045 0.081
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.045 0.100
LHB LHB: Lutropin subunit beta precursor 0.045 0.081
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.045 0.202
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.045 0.126
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.045 0.072
RYR2 RYR2: Ryanodine receptor 2 0.045 0.041
CGA CGA: Glycoprotein hormones alpha chain precursor 0.045 0.126
TSHB TSHB: Thyrotropin subunit beta precursor 0.045 0.081
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.0446 0.098
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.044 6.81
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.044 0.029
PMP2 PMP2: Myelin P2 protein 0.044 0.029
ATRN N/A 0.044 0.148
CREB1 CREB1: cAMP response element-binding protein 0.044 0.030
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.075
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.047
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.075
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.075
TNN TNN: Tenascin-N precursor 0.042 0.030
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.034
SLC4A1 SLC4A1, AE1, DI, EPB3: Band 3 anion transport protein 0.041 0.035
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.041 0.028
CD82 CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen 0.041 0.056
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.041 0.111
FGF9 FGF9: Glia-activating factor precursor 0.041 0.073
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.090
LOC645745 MT1H: Metallothionein-1H 0.041 0.100
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.041 0.057
FKBP10 FKBP10, FKBP65, PSEC0056: FK506-binding protein 10 precursor 0.041 0.041
MT1X MT1X: Metallothionein-1X 0.041 0.126
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.041 0.072
MT1F MT1F, PRO0376: Metallothionein-1F 0.041 0.100
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.041 0.081
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.041 0.202
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.041 0.091
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.041 0.081
CP CP: Ceruloplasmin precursor 0.041 0.100
MT2A MT2A, CES1, MT2: Metallothionein-2 0.041 0.100
RYR1 0.041 0.041
F8 F8, F8C: Coagulation factor VIII precursor 0.041 0.072
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.041 0.075
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.041 0.056
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.041 0.073
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.041 0.073
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.041 0.073
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.041 0.064
DLG2 DLG2: Disks large homolog 2 0.041 0.090
OPTC OPTC, OPT: Opticin precursor 0.04 0.083
TMPRSS9 N/A 0.04 0.025
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.04 0.083
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.04 0.083
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.04 0.052
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.040 0.097
GNAI2 Galphai2 protein 0.040 0.049
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.040 56.70
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.038 0.026
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.037 0.055
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.037 0.025
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.037 0.049
TNNC2 TNNC2: Troponin C, skeletal muscle 0.037 0.029
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.037 0.073
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.037 0.064
SPARC SPARC, ON: SPARC precursor 0.037 0.064
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.037 0.058
FKBP9 FKBP9, FKBP60, FKBP63: FK506-binding protein 9 precursor 0.037 0.046
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.036 0.100
AQP4 AQP4: Aquaporin-4 0.036 0.047
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.036 0.025
KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 0.034 0.032
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.034 0.047
MT1E MT1E: Metallothionein-1E 0.034 0.038
PVALB PVALB: Parvalbumin alpha 0.033 0.029
RAP1GA1 N/A 0.033 0.025
RHO RHO, OPN2: Rhodopsin 0.033 0.062
SELE SELE, ELAM1: E-selectin precursor 0.033 0.109
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.033 0.073
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.032 0.055
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 0.032 0.055
THBD THBD, THRM: Thrombomodulin precursor 0.032 0.123
YWHAQ YWHAQ: 14-3-3 protein theta 0.032 0.029
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.031 0.026
DBN1 DBN1, D0S117E: Drebrin 0.031 0.027
AQP1 AQP1, CHIP28: Aquaporin-1 0.0308 0.027
VIL1 VIL1, VIL: Villin-1 0.0308 0.027
AQP2 AQP2: Aquaporin-2 0.0308 0.027
PEBP1 PEBP1, PBP, PEBP: Phosphatidylethanolamine-binding protein 1 0.031 0.034
PPP1R14D PPP1R14D, GBPI: Protein phosphatase 1 regulatory subunit 14D 0.031 0.030
GJA5 GJA5: Gap junction alpha-5 protein 0.030 0.0782
CNN1 CNN1: Calponin-1 0.030 0.0338
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.030 0.038
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.030 0.038
PPP1R1A PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A 0.030 0.0338
CAV2 CAV2: Caveolin-2 0.030 0.0338
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.030 0.0338
SPOCK2 SPOCK2, KIAA0275, UNQ269/PRO306, TICN2: Testican-2 precursor 0.030 0.0273
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.030 0.086
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.030 0.044
C1QBP C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot 0.030 0.030
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.030 0.098
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.030 0.098
CHAT CHAT: Choline O-acetyltransferase 0.030 0.030
GP9 GP9: Platelet glycoprotein IX precursor 0.030 0.055
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.029 0.0308
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.029 0.069
GABRR1 N/A 0.029 0.062
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.029 0.062
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.029 0.096
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.029 0.062
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.029 0.077
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.029 0.062
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.029 0.0308
TSHR N/A 0.029 0.0308
GLRA1 N/A 0.029 0.056
HPN HPN, TMPRSS1: Serine protease hepsin 0.029 0.056
BLNK BLNK, SLP65, BASH: B-cell linker protein (Fragment) 0.0288 0.0288
TNS1 TNS1, TNS: Tensin-1 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
SOCS6 SOCS6, CIS4, SOCS4: Suppressor of cytokine signaling 6 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
PIK3R1 PIK3R1, GRB1: Phosphatidylinositol 3-kinase regulatory subunit alpha 0.0288 0.0288
VAV3 VAV-like protein (Fragment) 0.0288 0.0288
BTK N/A 0.0288 0.0288
INPP5D N/A 0.0288 0.0288
GRB10 Adapter protein (Fragment) 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
TENC1 N/A 0.0288 0.0288
PIK3R3 PIK3R3: Phosphatidylinositol 3-kinase regulatory subunit gamma 0.0288 0.0288
DAPP1 DAPP1, BAM32, HSPC066: Dual adapter for phosphotyrosine and 3-phosphotyrosine an 0.0288 0.0288
FGR FGR, RP1-159A19.2-007: Gardner-Rasheed feline sarcoma viral (Fragment) 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK N/A 0.0288 0.0288
SYK N/A 0.0288 0.0288
BLNK N/A 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.049
CAV1 CAV1, CAV: Caveolin-1 0.0273 0.034
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
ST8SIA4 ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe 0.027 0.045
VIM VIM: Vimentin 0.027 0.025
ANXA9 ANXA9, ANX31: Annexin A9 0.0263 0.039
GP1BA N/A 0.0263 0.096
KCNJ1 KCNJ1, ROMK1: ATP-sensitive inward rectifier potassium channel 1 0.0263 0.026
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.026 0.035
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.026 0.056
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.026 0.049
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.026 0.0308
GLRB GLRB: Glycine receptor subunit beta precursor 0.026 0.028
INPPL1 INPPL1, SHIP2: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 0.0258 0.0258
FES N/A 0.0258 0.0258
SHC2 N/A 0.0258 12.40
SOCS7 SOCS7, NAP4, SOCS6: Suppressor of cytokine signaling 7 0.0258 0.0258
0.572
Total Score 6.35E4