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Evidence of Interaction Between CBLB and RASSF1

The interaction score between CBLB and RASSF1 is 2.50.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between CBLB and RASSF1 = 0.80

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.027
Orthology N/A N/A
Domains No domains were used in calculating likelihood of interaction N/A
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation No localisation data was used in calculating likelihood of interaction
Transitive Score

The common interactors between CBLB and RASSF1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CBLB andRASSF1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CBLB has 1522 interactors and RASSF1 has 82 interactors of which there are 31 common interactors.

Common InteractorName of Common InteractorScore for CBLB-Interactor (?)Score for RASSF1-Interactor (?)
ZAP70 ZAP70: Uncharacterized protein ZAP70 9.65 0.027
JAK1 4.52 0.027
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 1.62 0.027
STK10 STK10: Uncharacterized protein STK10 1.62 0.027
FYN N/A 1.11 0.027
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 1.11 0.027
BTN3A3 BTN3A3, BTF3: Butyrophilin subfamily 3 member A3 precursor 0.392 0.082
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.385 0.027
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.304 0.027
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.214 0.027
ID2 ID2: DNA-binding protein inhibitor ID-2 0.144 0.027
ARHGEF3 ARHGEF3: Rho guanine nucleotide exchange factor 3 0.137 0.027
BTN3A2 BTN3A2, BT3.2, BTF3, BTF4: Butyrophilin subfamily 3 member A2 precursor 0.130 0.027
NCR3 NCR3, 1C7, LY117: Natural cytotoxicity triggering receptor 3 precursor 0.130 0.027
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.027
RP6-213H19.1 MST4, MASK: Serine/threonine-protein kinase MST4 0.123 0.027
CD7 CD7: T-cell antigen CD7 precursor 0.076 0.027
CSNK1G2 CSNK1G2: Casein kinase I isoform gamma-2 0.074 0.027
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.066 0.027
HLA-F HLA-F, HLA-5.4, HLAF: HLA class I histocompatibility antigen, alpha chain F prec 0.061 0.027
IL18RAP IL18RAP: Interleukin-18 receptor accessory protein precursor 0.061 0.027
HLA-E HLA-E, XXbac-BPG34K20.2-001: MHC class Ib antigen 0.061 0.027
ADCY7 ADCY7, KIAA0037: Adenylate cyclase type 7 0.055 0.027
SIPA1 SIPA1, SPA1: Signal-induced proliferation-associated protein 1 0.042 0.027
ITGB7 ITGB7: Integrin beta-7 precursor 0.038 0.027
CD160 CD160, BY55: CD160 antigen precursor 0.037 0.027
CD300A CD300A, CMRF35H: CMRF35-H antigen precursor 0.037 0.027
ADAM8 ADAM8, MS2: ADAM 8 precursor 0.0331 0.027
GIMAP6 IAN6: Immune associated nucleotide 6c 0.027 0.027
MBNL1 MBNL1, EXP, KIAA0428, MBNL: Muscleblind-like protein 1 0.027 0.027
RARRES3 RARRES3, RIG1, TIG3: Retinoic acid receptor responder protein 3 0.027 0.027
0.228
Total Score 2.50