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Evidence of Interaction Between FRS3 and PDGFRB

The interaction score between FRS3 and PDGFRB is 1.92E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between FRS3 and PDGFRB = 0.04

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.85E-3
Orthology
OrganismFRS3 OrthologuePDGFRB OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00107698 0.379 IPI00022296 0.132
human IPI00107698 0.379 IPI00027721 0.325
human IPI00107698 0.379 IPI00018335 1
human IPI00107698 0.379 IPI00021396 1
  • InVitro

Get References From PubMed
human IPI00107698 0.379 IPI00293565 0.322
human IPI00107698 0.379 IPI00005722 0.081
worm O44830 1 P34892 0.084
worm O44830 1 O76698 1
worm O44830 1 Q21038 1
worm O44830 1 Q21041 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.58
Domains Domains present in FRS3 and PDGFRB:
Domains in FRS3Domains in PDGFRB
IPR002404 Insulin receptor substrate-1, PTB
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.

The Chi square scores for co-occurrence of domains that are present in FRS3 and PDGFRB are listed below.

Domain 1Domain 2Chi Square
IPR002404 Insulin receptor substrate-1, PTB IPR008266 Tyrosine protein kinase, active site 29.1589
IPR002404 Insulin receptor substrate-1, PTB IPR001245 Tyrosine protein kinase 26.3566
IPR002404 Insulin receptor substrate-1, PTB IPR000719 Protein kinase 11.2932
IPR002404 Insulin receptor substrate-1, PTB IPR011009 Protein kinase-like 2.18531
IPR002404 Insulin receptor substrate-1, PTB IPR003598 Immunoglobulin C-2 type 1.20381
IPR002404 Insulin receptor substrate-1, PTB IPR007110 Immunoglobulin-like 0.621518
IPR002404 Insulin receptor substrate-1, PTB IPR003599 Immunoglobulin subtype 0.1448

The background colour of the table refers to:

  • Blue Domain is only present in FRS3
  • Yellow Domain is only present in PDGFRB
  • Green Domain is present in both FRS3 and PDGFRB

 0.109
Post-translational Modifications

Protein: FRS3

PTMResidueReference
Phosphorylation 417 PubMed, HPRD
Phosphorylation 455 PubMed, HPRD

Protein: PDGFRB

PTMResidueReference
Dephosphorylation 562 PubMed, HPRD
Dephosphorylation 579 PubMed, HPRD
Dephosphorylation 740 PubMed, HPRD
Dephosphorylation 751 PubMed, HPRD
Dephosphorylation 771 PubMed, HPRD
Dephosphorylation 857 PubMed, HPRD
Dephosphorylation 1009 PubMed, HPRD
Dephosphorylation 1021 PubMed, HPRD
Phosphorylation 579 PubMed, HPRD
Phosphorylation 581 PubMed, HPRD
Phosphorylation 716 PubMed, HPRD
Phosphorylation 740 PubMed, HPRD
Phosphorylation 751 PubMed, HPRD
Phosphorylation 763 PubMed, HPRD
Phosphorylation 771 PubMed, HPRD
Phosphorylation 775 PubMed, HPRD
Phosphorylation 857 PubMed, HPRD
Phosphorylation 1009 PubMed, HPRD
Phosphorylation 1021 PubMed, HPRD
Phosphotyrosine 751 PubMed, HPRD
Phosphotyrosine 857 PubMed, HPRD
Localisation

Protein: FRS3

LocalisationReference
Plasma membrane HPRD
Cytoplasm HPRD

Protein: PDGFRB

LocalisationReference
Plasma membrane HPRD
Transitive Score

The common interactors between FRS3 and PDGFRB that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between FRS3 andPDGFRB. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , FRS3 has 917 interactors and PDGFRB has 1323 interactors of which there are 552 common interactors.

Common InteractorName of Common InteractorScore for FRS3-Interactor (?)Score for PDGFRB-Interactor (?)
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 130.00 183.00
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 82.20 0.026
CRKL CRKL: Crk-like protein 65.60 536.00
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 65.60 0.033
NCK2 NCK2: Cytoplasmic protein NCK2 46.80 600.00
KIT KIT: Mast/stem cell growth factor receptor precursor 35.00 112.00
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 35.00 532.00
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 30.80 112.00
GRAP GRAP: GRB2-related adapter protein 8.58 133.00
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.372 0.073
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.307 0.644
RIN1 RIN1: Ras and Rab interactor 1 0.275 0.520
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.275 0.029
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.275 0.033
IL9R IL9R: Interleukin-9 receptor precursor 0.274 0.109
STK16 N/A 0.251 0.032
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.251 0.0453
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.251 0.731
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.245 0.035
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.225 0.029
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.225 0.073
SORBS3 SORBS3, SCAM1: Vinexin 0.225 0.073
TLN1 TLN1: Uncharacterized protein TLN1 0.225 0.064
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.225 0.026
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.225 0.033
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.202 0.123
BMX N/A 0.191 0.902
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.191 1.13
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.191 0.644
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.191 0.065
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.191 0.126
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.191 0.065
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.191 0.731
PLD2 PLD2: Phospholipase D2 0.188 0.073
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.181 0.111
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.171 0.065
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.171 0.051
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.171 0.033
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.171 15.80
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.171 0.033
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.171 277.00
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.171 0.033
MYO3A MYO3A: Myosin IIIA 0.171 0.041
APS SH2B2, APS: SH2B adapter protein 2 0.171 0.586
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.171 0.064
CDK4 CDK4: Cell division protein kinase 4 0.171 0.029
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.171 0.044
CDK2 CDK2: Cell division protein kinase 2 0.171 0.026
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.980
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.980
MAPK15 N/A 0.165 0.049
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.165 0.980
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.165 0.109
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.165 0.980
MAP2K5 N/A 0.165 0.049
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.049
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.165 0.109
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.980
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.165 0.109
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.980
AMPH AMPH, AMPH1: Amphiphysin 0.165 0.109
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.980
NF2 NF2, SCH: Merlin 0.165 0.109
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.109
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.049
CDK6 CDK6: Cell division protein kinase 6 0.152 0.032
CTTN CTTN, EMS1: Src substrate cortactin 0.152 0.126
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.152 0.033
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.152 0.032
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.152 0.033
SPTAN1 N/A 0.152 0.081
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.152 0.033
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.152 0.731
ROCK1 ROCK1: Rho-associated protein kinase 1 0.152 0.0727
WEE1 WEE1: Wee1-like protein kinase 0.152 0.032
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.152 0.081
DCC DCC: Netrin receptor DCC precursor 0.148 0.097
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.148 0.046
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.148 0.136
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.148 0.111
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.148 0.136
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.098
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.148 0.098
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.148 0.098
CDC2 CDC2: Cell division control protein 2 homolog 0.148 0.044
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 422.00
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.148 0.044
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.148 0.098
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.098
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.148 0.098
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.098
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 1.01E3
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.098
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.044
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.148 0.075
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.098
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.044
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.098
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.098
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.148 0.044
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.098
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.148 0.044
STAT3 0.148 0.878
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.098
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.136 315.00
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.136 0.064
CDK7 CDK7, MO15: Cell division protein kinase 7 0.136 0.026
CDK5 CDK5: Cell division protein kinase 5 0.136 0.026
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.136 0.029
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.136 0.064
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.136 0.029
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.136 0.029
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.136 0.029
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.136 0.065
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.136 0.044
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.136 0.051
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.136 0.029
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.136 0.029
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.136 0.026
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.136 0.171
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.136 0.065
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.136 74.00
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.136 0.808
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.033
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.136 0.026
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.136 0.033
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.136 0.064
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.136 0.029
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.136 0.029
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.126 0.123
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.126 0.109
CDH2 CDH2, CDHN, NCAD: Cadherin-2 precursor 0.126 0.062
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.126 0.123
PCDH7 PCDH7, BHPCDH: Protocadherin-7 precursor 0.126 0.062
CDH13 CDH13, CDHH: Cadherin-13 precursor 0.126 0.062
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.126 0.055
STAT2 STAT2: Signal transducer and activator of transcription 2 0.126 0.320
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.123 0.098
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.123 0.032
CDKL5 N/A 0.123 0.0453
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.123 0.029
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.123 0.037
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.123 0.654
PRKAA1 N/A 0.123 0.032
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.123 0.032
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.123 0.058
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.123 0.654
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.123 0.072
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.123 0.0727
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.123 0.033
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.114 0.090
PLD1 PLD1: Phospholipase D1 0.114 0.073
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.113 0.233
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.113 82.20
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.113 0.136
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.113 0.136
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.113 0.111
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.113 0.111
NEO1 NEO1, NGN: Neogenin precursor 0.113 0.111
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.111 0.026
CD2AP CD2AP: CD2-associated protein 0.111 0.065
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.111 0.113
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.111 0.041
PMP2 PMP2: Myelin P2 protein 0.111 0.027
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.111 12.50
RPS6KB1 N/A 0.111 0.026
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.111 0.029
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.111 0.065
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.111 0.112
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.111 0.033
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.111 0.073
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.111 0.065
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.111 600.00
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.111 0.029
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.111 0.029
TLN2 TLN2: Uncharacterized protein TLN2 0.111 0.073
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.111 0.655
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.111 0.029
FNBP1 N/A 0.111 0.065
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.111 0.029
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.111 0.065
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.111 0.058
STAM2 STAM2: Signal transducing adapter molecule 2 0.111 0.064
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.111 12.50
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.111 0.026
DYRK3 N/A 0.111 0.033
RDX RDX: Radixin 0.111 0.073
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.111 0.058
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.111 0.026
CSK CSK: Tyrosine-protein kinase CSK 0.111 0.586
CXorf9 N/A 0.111 0.065
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.111 0.033
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.109 0.165
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.109 0.165
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.109 0.165
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.109 0.165
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.109 0.165
FN1 N/A 0.109 0.165
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.109 0.165
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.109 0.165
CDH6 CDH6: Cadherin-6 precursor 0.109 0.083
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.109 0.165
MUCDHL MUPCDH, MUCDHL, UNQ2781/PRO7168: Mucin and cadherin-like protein precursor 0.109 0.083
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.165
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.109 0.165
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.109 0.165
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.165
PCDHA2 PCDHA2: Protocadherin alpha 2 precursor 0.109 0.083
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.109 0.065
JAK1 0.109 0.644
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.109 0.033
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.109 0.0727
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.109 0.029
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.109 0.644
SYK SYK: Tyrosine-protein kinase SYK 0.109 0.654
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.109 0.654
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.109 0.581
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.109 0.581
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.109 0.581
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.109 0.581
PVR PVR, PVS: Poliovirus receptor precursor 0.101 0.123
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.100 0.109
PTPRZ1 N/A 0.100 0.098
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.100 0.123
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.100 0.123
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.100 0.049
CDH5 CDH5: Cadherin-5 precursor 0.100 0.127
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.100 0.109
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.100 0.251
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.098 0.032
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.098 0.065
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.098 0.030
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.098 0.148
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.098 0.030
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.098 232.00
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.098 0.062
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.098 0.148
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.098 0.075
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.098 0.025
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.148
CNTN1 CNTN1: Contactin-1 precursor 0.098 0.148
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.098 0.075
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.098 0.148
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.098 0.148
CNTN4 CNTN4: Contactin-4 precursor 0.098 0.148
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.148
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.097 0.041
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.097 0.058
STK10 STK10: Uncharacterized protein STK10 0.097 0.029
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.097 281.00
LYN LYN: Tyrosine-protein kinase Lyn 0.097 0.586
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.097 0.520
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.097 250.00
ATM ATM: Serine-protein kinase ATM 0.097 0.029
MSN MSN: Moesin 0.097 0.058
STAT6 STAT6: Signal transducer and activator of transcription 6 0.097 250.00
HCK N/A 0.097 250.00
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.097 0.041
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.097 250.00
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.097 281.00
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.097 0.029
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.097 0.026
VIL2 N/A 0.097 0.064
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.097 0.064
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.097 0.051
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.097 0.026
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.097 277.00
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.097 0.065
VAV1 VAV1, VAV: Proto-oncogene vav 0.097 281.00
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.090
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.097 0.065
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.097 0.058
MCF2 MCF2, DBL: Proto-oncogene DBL 0.096 0.072
GAB1 GAB1: GRB2-associated-binding protein 1 0.096 0.072
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.096 0.081
ALK ALK: ALK tyrosine kinase receptor precursor 0.094 0.064
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.090 0.088
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.090 0.088
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.090 0.097
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.090 0.097
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.090 0.049
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.090 0.111
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.090 0.056
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.090 372.00
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.087 0.064
DOK1 DOK1: Docking protein 1 0.086 0.058
PSCD2 N/A 0.083 0.109
DNM3 DNM3: Uncharacterized protein DNM3 0.083 0.109
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.083 0.109
DSG2 DSG2: Desmoglein-2 precursor 0.081 0.055
DSG3 DSG3: Desmoglein-3 precursor 0.081 0.062
MET MET: Hepatocyte growth factor receptor precursor 0.081 0.123
ATP2B1 N/A 0.081 0.056
GHR GHR: Growth hormone receptor precursor 0.081 0.191
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.081 0.063
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.081 0.191
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.081 0.152
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.0794 0.081
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.077 0.065
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.077 0.072
IRS1 IRS1: Insulin receptor substrate 1 0.077 0.126
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.044
ARHGEF7 N/A 0.075 0.098
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.075 0.098
ELMO1 N/A 0.075 0.098
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.098
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.075 0.098
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.098
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.074 0.109
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.073 0.171
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.073 0.275
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.073 0.097
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.073 0.225
SOS1 SOS1: Son of sevenless homolog 1 0.073 0.046
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.073 137.00
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.073 0.136
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.073 0.097
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.072 0.360
SORL1 SORL1: Sortilin-related receptor precursor 0.072 0.110
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.072 0.123
ITGB4 N/A 0.072 0.109
F3 F3: Tissue factor precursor 0.072 0.123
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.072 0.355
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.072 0.109
PRLR PRLR: Prolactin receptor precursor 0.072 0.123
DSC2 DSC2, DSC3: Desmocollin-2 precursor 0.072 0.062
EPOR EPOR: Erythropoietin receptor precursor 0.072 0.109
CDH17 CDH17: Cadherin-17 precursor 0.072 0.055
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.072 0.098
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.072 0.110
CRLF3 N/A 0.072 0.088
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.071 0.064
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.069 0.058
RASA3 RASA3: Ras GTPase-activating protein 3 0.069 0.073
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.0688 0.109
ITGB7 ITGB7: Integrin beta-7 precursor 0.064 0.088
STAT4 STAT4: Signal transducer and activator of transcription 4 0.064 0.286
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.372
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.064 0.056
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.064 0.318
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.064 0.088
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.064 0.029
TNC TNC, HXB: Tenascin precursor 0.064 0.275
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.063 0.081
GAB2 N/A 0.062 0.065
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.062 0.081
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.062 0.098
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.061 0.152
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.061 0.109
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.058 0.041
INSR INSR: Insulin receptor precursor 0.058 0.136
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.057 0.110
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.057 0.152
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.057 0.098
PSD TYL: TYL protein 0.056 0.058
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.056 0.058
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.056 0.052
TTN N/A 0.056 0.073
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.056 0.058
IRS2 IRS2: Insulin receptor substrate 2 0.055 0.072
GRLF1 N/A 0.052 0.072
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.052 0.037
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.617
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.617
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
ITGB1 ITGB1, FNRB, MDF2, MSK12: Integrin beta-1 precursor 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
MARK2 N/A 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
GRB10 N/A 0.051 0.617
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.051
PTPRA N/A 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.617
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
NCAM1 N/A 0.051 0.051
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.040
TRIP10 N/A 0.050 0.039
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.050 0.143
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.165
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.049 0.165
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.049 0.165
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.049 0.165
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.049 0.083
NULL A1BG: Alpha-1B-glycoprotein precursor 0.049 0.165
GMIP GMIP: GEM-interacting protein 0.049 0.065
PSCD4 PSCD4, CYT4: Cytohesin-4 0.049 0.065
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.049 0.065
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.046 0.109
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.046 0.123
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 265.00
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.553
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.046
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.046 0.026
DLG2 DLG2: Disks large homolog 2 0.046 0.073
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.0453 0.049
ITGAE ITGAE: Integrin alpha-E precursor 0.0453 0.110
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.0453 0.251
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.0453 0.251
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.0453 0.098
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.0453 0.096
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.045 0.202
SHB SHB: SH2 domain-containing adapter protein B 0.044 0.145
ATP2A3 ATP2A3: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 0.044 0.083
BSG N/A 0.044 0.148
ATRN N/A 0.044 0.148
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.043 0.058
DAB1 DAB1: Disabled homolog 1 0.043 0.064
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.043 0.058
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.0425 0.029
RAB11FIP5 RAB11FIP5, GAF1, KIAA0857, RIP11: Rab11 family-interacting protein 5 0.0425 0.037
TNN TNN: Tenascin-N precursor 0.042 0.034
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.0416 0.065
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.041 0.086
GRB7 GRB7: Growth factor receptor-bound protein 7 0.041 0.162
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.04 0.165
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.04 0.165
KIR3DL1 N/A 0.04 0.165
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.04 0.165
VASP VASP: Vasodilator-stimulated phosphoprotein 0.039 0.065
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.039 0.166
FAT4 FATJ, FAT4: FAT tumor suppressor homolog 4 0.038 0.0253
STMN1 STMN1, LAP18, OP18: Stathmin 0.038 0.052
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.038 0.073
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.038 0.073
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.037 0.123
GPA33 GPA33: Cell surface A33 antigen precursor 0.037 0.123
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.037 0.152
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.037 0.098
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 0.037 0.062
PLEK PLEK, P47: Pleckstrin 0.037 0.046
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.037 0.109
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.037 0.041
FABP1 FABP1, FABPL: Fatty acid-binding protein, liver 0.037 0.0263
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.035 0.090
DAB2 DAB2, DOC2: Disabled homolog 2 0.035 0.148
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.033 0.029
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.033 0.030
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.032 0.098
EGF EGF: Pro-epidermal growth factor precursor 0.032 0.123
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.032 0.152
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.032 0.051
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.0727
DBN1 DBN1, D0S117E: Drebrin 0.032 0.030
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.032 0.033
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.029
CENTA1 CENTA1: Centaurin-alpha 1 0.031 0.046
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.031 0.046
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.0308 0.065
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.0308 0.090
SOCS5 SOCS5, CIS6, CISH5, CISH6, KIAA0671: Suppressor of cytokine signaling 5 0.0308 0.200
SASH1 SASH1, KIAA0790, PEPE1: SAM and SH3 domain-containing protein 1 0.0308 0.039
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.030 0.098
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.030 0.110
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.030 0.109
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.030 0.109
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.030 0.109
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.030 0.098
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.030 0.123
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.030 0.191
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.030 0.152
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.030 0.109
KIAA0690 N/A 0.029 0.029
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.029 0.029
SYMPK SYMPK, SPK: Symplekin 0.029 0.026
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.029 0.029
AQP2 AQP2: Aquaporin-2 0.029 0.027
CTPS CTPS: CTP synthase 1 0.029 0.029
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.029 0.029
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.029 0.029
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.109
COTL1 COTL1, CLP: Coactosin-like protein 0.028 0.04
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.04
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.028 0.04
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.028 0.049
PPEF1 N/A 0.028 0.109
CNN2 CNN2: Calponin-2 0.028 0.109
MYO18A 0.028 0.049
CASP8 CASP8, MCH5: Caspase-8 precursor 0.028 0.049
TSC2 TSC2, TSC4: Tuberin 0.028 0.049
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.04
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.109
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.028 0.109
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.028 0.109
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.028 0.041
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.028 0.181
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.028 0.181
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.028 0.181
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.027 0.037
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.217
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.265
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.217
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.217
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.217
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.0263 0.098
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.0263 0.098
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.0263 0.098
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.0263 0.110
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.0263 0.098
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.0263 0.098
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.0263 0.098
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.0263 0.110
LILRB1 N/A 0.0263 0.110
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.0263 0.098
CD7 CD7: T-cell antigen CD7 precursor 0.0263 0.109
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.0263 0.098
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.0263 0.098
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.026 0.064
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.026 0.026
SOD3 SOD3: Extracellular superoxide dismutase [Cu-Zn] precursor 0.026 0.036
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.026 0.037
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.026 0.072
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.026 0.037
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.081
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.026 0.033
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.025 0.061
ITIH4 ITIH4, IHRP, PRO1851, ITIHL1, PK120: Inter-alpha-trypsin inhibitor heavy chain H 0.025 0.032
C2 C2: Complement C2 precursor 0.025 0.0453
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.025 0.101
SNX3 N/A 0.025 0.098
CFL2 CFL2: Cofilin-2 0.025 0.036
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.098
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.025 0.044
SVIL SVIL: Supervillin 0.025 0.036
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.044
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.098
NIPBL N/A 0.025 0.044
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.044
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.098
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.098
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.098
GSN GSN: Gelsolin precursor 0.025 0.036
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.044
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.098
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.098
0.572
Total Score 1.92E4