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Evidence of Interaction Between PDGFRB and STAT6

The interaction score between PDGFRB and STAT6 is 2.27E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between PDGFRB and STAT6 = -0.16

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

1.48E-3
Orthology
OrganismPDGFRB OrthologueSTAT6 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00022296 0.132 IPI00030783 0.179
  • InVivo

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human IPI00027721 0.325 IPI00030783 0.179
  • InVitro

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human IPI00018335 1 IPI00030783 0.179
human IPI00021396 1 IPI00030783 0.179
human IPI00293565 0.322 IPI00030783 0.179
human IPI00005722 0.081 IPI00030783 0.179
human IPI00022296 0.132 IPI00103415 0.179
  • InVivo

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human IPI00027721 0.325 IPI00103415 0.179
  • InVitro

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human IPI00018335 1 IPI00103415 0.179
human IPI00021396 1 IPI00103415 0.179
human IPI00293565 0.322 IPI00103415 0.179
human IPI00005722 0.081 IPI00103415 0.179
worm P34892 0.084 Q9NAD6 0.179
worm O76698 1 Q9NAD6 0.179
worm Q21038 1 Q9NAD6 0.179
worm Q21041 1 Q9NAD6 0.179

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

1.07
Domains Domains present in PDGFRB and STAT6:
Domains in PDGFRBDomains in STAT6
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.
IPR008967 p53-like transcription factor, DNA-binding
IPR000980 SH2 motif
IPR001217 STAT protein
IPR011992 EF-Hand_type.
IPR012345 STAT_DNA_bd.

The Chi square scores for co-occurrence of domains that are present in PDGFRB and STAT6 are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR003599 Immunoglobulin subtype IPR000980 SH2 motif 66.4833
IPR003598 Immunoglobulin C-2 type IPR000980 SH2 motif 64.7072
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR013151 Immunoglobulin. IPR000980 SH2 motif 36.9251
IPR008266 Tyrosine protein kinase, active site IPR012345 STAT_DNA_bd. 22.9582
IPR008266 Tyrosine protein kinase, active site IPR001217 STAT protein 22.9582
IPR000719 Protein kinase IPR011992 EF-Hand_type. 15.5567
IPR001245 Tyrosine protein kinase IPR012345 STAT_DNA_bd. 11.9355
IPR001245 Tyrosine protein kinase IPR001217 STAT protein 11.9355
IPR011009 Protein kinase-like IPR011992 EF-Hand_type. 9.34155
IPR007110 Immunoglobulin-like IPR011992 EF-Hand_type. 6.99538
IPR001245 Tyrosine protein kinase IPR011992 EF-Hand_type. 6.38624
IPR000719 Protein kinase IPR012345 STAT_DNA_bd. 2.68473
IPR000719 Protein kinase IPR001217 STAT protein 2.68473
IPR003599 Immunoglobulin subtype IPR011992 EF-Hand_type. 2.41821
IPR011009 Protein kinase-like IPR012345 STAT_DNA_bd. 1.35691
IPR011009 Protein kinase-like IPR001217 STAT protein 1.35691
IPR008266 Tyrosine protein kinase, active site IPR011992 EF-Hand_type. 1.24952
IPR001245 Tyrosine protein kinase IPR008967 p53-like transcription factor, DNA-binding 0.940239
IPR007110 Immunoglobulin-like IPR012345 STAT_DNA_bd. 0.70476
IPR007110 Immunoglobulin-like IPR001217 STAT protein 0.70476
IPR003598 Immunoglobulin C-2 type IPR011992 EF-Hand_type. 0.490157
IPR000719 Protein kinase IPR008967 p53-like transcription factor, DNA-binding 0.163761
IPR008266 Tyrosine protein kinase, active site IPR008967 p53-like transcription factor, DNA-binding 0.133003
IPR003599 Immunoglobulin subtype IPR012345 STAT_DNA_bd. 0.101522
IPR003599 Immunoglobulin subtype IPR001217 STAT protein 0.101522
IPR013151 Immunoglobulin. IPR011992 EF-Hand_type. 0.0700765
IPR011009 Protein kinase-like IPR008967 p53-like transcription factor, DNA-binding 0.00476462

The background colour of the table refers to:

  • Blue Domain is only present in PDGFRB
  • Yellow Domain is only present in STAT6
  • Green Domain is present in both PDGFRB and STAT6

0.980
Post-translational Modifications

Protein: PDGFRB

PTMResidueReference
Dephosphorylation 562 PubMed, HPRD
Dephosphorylation 579 PubMed, HPRD
Dephosphorylation 740 PubMed, HPRD
Dephosphorylation 751 PubMed, HPRD
Dephosphorylation 771 PubMed, HPRD
Dephosphorylation 857 PubMed, HPRD
Dephosphorylation 1009 PubMed, HPRD
Dephosphorylation 1021 PubMed, HPRD
Phosphorylation 579 PubMed, HPRD
Phosphorylation 581 PubMed, HPRD
Phosphorylation 716 PubMed, HPRD
Phosphorylation 740 PubMed, HPRD
Phosphorylation 751 PubMed, HPRD
Phosphorylation 763 PubMed, HPRD
Phosphorylation 771 PubMed, HPRD
Phosphorylation 775 PubMed, HPRD
Phosphorylation 857 PubMed, HPRD
Phosphorylation 1009 PubMed, HPRD
Phosphorylation 1021 PubMed, HPRD
Phosphotyrosine 751 PubMed, HPRD
Phosphotyrosine 857 PubMed, HPRD

Protein: STAT6

PTMResidueReference
Phosphorylation 641 PubMed, HPRD
Localisation

Protein: PDGFRB

LocalisationReference
Plasma membrane HPRD

Protein: STAT6

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PDGFRB and STAT6 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PDGFRB andSTAT6. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PDGFRB has 1323 interactors and STAT6 has 1882 interactors of which there are 777 common interactors.

Common InteractorName of Common InteractorScore for PDGFRB-Interactor (?)Score for STAT6-Interactor (?)
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 1.01E3 1.17
NCK2 NCK2: Cytoplasmic protein NCK2 600.00 0.372
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 600.00 370.00
CRKL CRKL: Crk-like protein 536.00 132.00
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 532.00 0.520
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 422.00 0.148
STAT5B STAT5B: Signal transducer and activator of transcription 5B 372.00 330.00
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 315.00 0.099
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 281.00 12.80
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 281.00 0.225
VAV1 VAV1, VAV: Proto-oncogene vav 281.00 1.62
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 277.00 420.00
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 277.00 0.874
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 265.00 0.046
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 250.00 0.461
HCK N/A 250.00 6.03
JAK2 JAK2: Tyrosine-protein kinase JAK2 250.00 2.90E3
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 232.00 131.00
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 183.00 0.465
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 147.00 7.67
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 137.00 0.073
GRAP GRAP: GRB2-related adapter protein 133.00 13.20
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 112.00 1.06E3
KIT KIT: Mast/stem cell growth factor receptor precursor 112.00 0.577
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 84.00 0.097
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 82.20 0.655
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 74.00 0.620
JUP JUP, CTNNG, DP3: Junction plakoglobin 37.90 0.043
SHC2 N/A 29.70 1.29
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 19.20 0.066
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 15.80 0.099
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 12.50 0.097
PRKCG PRKCG, PKCG: Protein kinase C gamma type 12.50 0.088
SHC4 SHC-transforming protein 4 2.58 1.07
LOC392481 N/A 2.58 1.07
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 1.13 1.20
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 1.17
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 0.148
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.165
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.916 0.233
BMX N/A 0.902 0.775
STAT3 0.878 22.50
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 0.694
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 1.98
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.731 0.191
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.731 0.775
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 0.770
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.654 12.80
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.654 0.852
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.654 6.03
SYK SYK: Tyrosine-protein kinase SYK 0.654 6.03
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.191
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 1.78
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.644 0.152
JAK1 0.644 3.64
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.051
CRK CRK: Proto-oncogene C-crk 0.617 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.051
GRB10 N/A 0.617 0.051
APS SH2B2, APS: SH2B adapter protein 2 0.586 0.171
LYN LYN: Tyrosine-protein kinase Lyn 0.586 12.80
CSK CSK: Tyrosine-protein kinase CSK 0.586 12.80
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.581 0.307
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 0.859
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.581 1.98
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.581 1.81
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.046
RIN1 RIN1: Ras and Rab interactor 1 0.520 0.111
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.520 856.00
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.372 0.064
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.360 0.561
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.072
STAT2 STAT2: Signal transducer and activator of transcription 2 0.320 0.166
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.318 0.245
STAT4 STAT4: Signal transducer and activator of transcription 4 0.286 17.10
TNC TNC, HXB: Tenascin precursor 0.275 0.064
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.275 0.065
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.251 0.581
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.251 0.058
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.251 0.065
VWF VWF, F8VWF: von Willebrand factor precursor 0.245 0.037
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.245 0.0308
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.233 0.064
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.225 0.064
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.027
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.202 0.041
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.202 0.045
CNN3 CNN3: Calponin-3 0.202 0.110
GHR GHR: Growth hormone receptor precursor 0.191 0.100
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.191 0.0727
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.0727
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.181 0.041
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.181 0.0308
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.181 0.041
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.181 0.041
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.181 0.097
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.171 0.099
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.171 0.655
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.166 0.045
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
KIR3DL1 N/A 0.165 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.049
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
FN1 N/A 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.109
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.878
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.152 0.654
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.152 0.065
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.152 0.072
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.152 0.081
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.152 0.100
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.152 0.065
DAB2 DAB2, DOC2: Disabled homolog 2 0.148 0.111
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.878
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.878
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.098
BSG N/A 0.148 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 46.90
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 422.00
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.098
ATRN N/A 0.148 0.044
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.098
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.136 0.577
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.136 0.655
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.136 0.655
INSR INSR: Insulin receptor precursor 0.136 0.577
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.136 0.520
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.136 0.520
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.129 0.402
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.129 0.041
FYN N/A 0.129 0.824
VAV3 VAV3: Protein vav-3 0.128 0.044
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.127 0.032
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.126 0.191
IRS1 IRS1: Insulin receptor substrate 1 0.126 0.123
CTTN CTTN, EMS1: Src substrate cortactin 0.126 0.088
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.125 0.041
PRLR PRLR: Prolactin receptor precursor 0.123 0.065
EGF EGF: Pro-epidermal growth factor precursor 0.123 0.072
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.123 0.065
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.123 0.072
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.081
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.123 0.181
MET MET: Hepatocyte growth factor receptor precursor 0.123 0.654
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.123 0.065
PVR PVR, PVS: Poliovirus receptor precursor 0.123 0.0727
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.072
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.072
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.166
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.058
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.123 0.100
F3 F3: Tissue factor precursor 0.123 0.072
RIN3 N/A 0.115 0.263
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.114 0.029
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.114 0.029
CHP CHP: Calcium-binding protein p22 0.113 0.071
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.113 0.088
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.112 0.049
PARVA PARVA, MXRA2: Alpha-parvin 0.111 0.078
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.111 0.577
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.111 0.586
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.111 0.029
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.111 0.052
NEO1 NEO1, NGN: Neogenin precursor 0.111 0.046
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.111 0.520
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.110 0.561
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.110 0.340
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.110 0.126
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.110 1.19
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.110 0.340
ITGAE ITGAE: Integrin alpha-E precursor 0.110 0.0446
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.110 0.074
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.110 0.157
SORL1 SORL1: Sortilin-related receptor precursor 0.110 0.561
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.110 1.19
LILRB1 N/A 0.110 0.561
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.110 0.126
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.109 0.047
NF2 NF2, SCH: Merlin 0.109 0.165
PPEF1 N/A 0.109 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.083
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.148
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.083
PSCD2 N/A 0.109 0.165
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.148
CGN N/A 0.109 0.049
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.083
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
CNN2 CNN2: Calponin-2 0.109 0.165
ITGB4 N/A 0.109 0.072
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.081
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.109 0.0727
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.109 0.415
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.126
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.109 0.202
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.109 0.100
EPOR EPOR: Erythropoietin receptor precursor 0.109 0.081
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.109 0.340
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.072
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.109 0.072
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.202
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.561
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.109 0.202
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.109 0.0727
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.109 0.037
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.109 0.100
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.101 0.045
S100A3 S100A3, S100E: Protein S100-A3 0.100 0.049
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.099 0.137
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.098 0.191
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.098 0.166
CD69 CD69: Early activation antigen CD69 0.098 0.036
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.126
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.098 3.59
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.075
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.098 0.166
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.166
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.098 0.202
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.126
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.098 0.066
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.098 0.561
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.098 3.59
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.098 1.19
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.098 0.072
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.098 0.274
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.098 0.274
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.098 3.59
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.098 0.561
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.098 0.340
PTPRZ1 N/A 0.098 0.065
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.047
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.148
ELMO1 N/A 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.025
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.075
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.148
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.098 0.025
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
SNX3 N/A 0.098 0.025
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.075
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.148
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.098 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
ARHGEF7 N/A 0.098 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.025
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.047
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.577
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.097 0.520
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.655
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.073
DCC DCC: Netrin receptor DCC precursor 0.097 0.064
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.096 0.075
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.096 0.032
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.090 0.111
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.099
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.090 0.078
MYL3 MYL3: Myosin light polypeptide 3 0.090 0.0308
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.136
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.088 0.808
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.088 0.058
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.088 1.07
ITGB7 ITGB7: Integrin beta-7 precursor 0.088 0.040
CRLF3 N/A 0.088 1.19
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.086 0.029
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.086 0.098
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.049
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.083 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 1.20
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.081 0.123
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.081 0.041
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.081 0.155
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.081 0.0971
S100A7 S100A7, PSOR1: Protein S100-A7 0.081 0.055
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.081 0.035
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.051
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.081 0.045
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.081 0.515
SPTAN1 N/A 0.081 0.110
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0782 0.034
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.077 0.153
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.098
JAG2 JAG2: Jagged-2 precursor 0.075 0.044
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.073 0.111
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.073 0.0308
RASA3 RASA3: Ras GTPase-activating protein 3 0.073 0.171
RDX RDX: Radixin 0.073 0.097
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.073 0.031
PLD1 PLD1: Phospholipase D1 0.073 0.136
SORBS3 SORBS3, SCAM1: Vinexin 0.073 0.097
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.073 0.0308
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.073 0.233
PLD2 PLD2: Phospholipase D2 0.073 0.136
TTN N/A 0.073 0.088
DLG2 DLG2: Disks large homolog 2 0.073 0.041
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.073 0.099
SH3BP5 N/A 0.073 0.046
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.073 0.099
TLN2 TLN2: Uncharacterized protein TLN2 0.073 0.070
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.0727 1.81
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.0727 0.139
ROCK1 ROCK1: Rho-associated protein kinase 1 0.0727 0.515
IPO7 IPO7: Uncharacterized protein IPO7 0.0727 0.032
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0727 0.515
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.098
S100B S100B: Protein S100-B 0.072 0.049
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.072 0.152
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.372
GRLF1 N/A 0.072 0.055
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.098
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.072 0.044
IRS2 IRS2: Insulin receptor substrate 2 0.072 0.307
GAB1 GAB1: GRB2-associated-binding protein 1 0.072 0.123
NOTCH4 N/A 0.069 0.026
CETN1 CETN1, CEN1, CETN: Centrin-1 0.0688 0.036
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.065 0.461
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.065 1.62
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.065 4.88
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.065 1.62
LCP1 LCP1, PLS2: Plastin-2 0.065 1.62
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.065 0.111
CXorf9 N/A 0.065 1.62
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.065 0.372
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.065 1.62
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.065 0.241
GMIP GMIP: GEM-interacting protein 0.065 0.822
PSCD4 PSCD4, CYT4: Cytohesin-4 0.065 0.763
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.065 4.88
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.065 0.461
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.065 0.139
CD2AP CD2AP: CD2-associated protein 0.065 0.372
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.065 0.171
FNBP1 N/A 0.065 0.763
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.251
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.065 0.0277
GAB2 N/A 0.065 0.251
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.065 0.852
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.065 0.260
VASP VASP: Vasodilator-stimulated phosphoprotein 0.065 0.852
SNCB SNCB: Beta-synuclein 0.065 0.0277
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.065 0.031
CSPG2 N/A 0.065 0.173
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.065 0.111
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.065 0.287
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.065 0.109
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.065 0.123
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.064 0.033
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.171
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.064 0.372
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.064 0.054
TLN1 TLN1: Uncharacterized protein TLN1 0.064 0.461
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.064 0.070
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.041
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.361
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.064 0.111
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.064 0.041
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.064 0.225
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.064 0.078
VIL2 N/A 0.064 0.372
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.136
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.064 0.372
DAB1 DAB1: Disabled homolog 1 0.064 0.088
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.065
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.062 0.072
HPN HPN, TMPRSS1: Serine protease hepsin 0.062 0.029
RHO RHO, OPN2: Rhodopsin 0.062 0.029
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.062 0.029
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.062 0.032
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.036
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.098
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.061 0.046
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.060 0.115
CNN1 CNN1: Calponin-1 0.059 0.0338
THOP1 THOP1: Thimet oligopeptidase 0.058 0.038
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.058 0.099
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.058 0.275
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.058 0.461
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.058 0.136
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.058 0.763
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.058 0.038
PSD TYL: TYL protein 0.058 0.088
MSN MSN: Moesin 0.058 1.62
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.058 0.275
DOK1 DOK1: Docking protein 1 0.058 0.763
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.058 0.763
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.058 0.129
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.058 1.62
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.058 0.078
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.058 0.136
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.058 0.275
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.058 1.81
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.056 0.029
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.056 0.137
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.056 0.090
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.056 0.067
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.148
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.056 0.340
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.056 0.100
ATP2B1 N/A 0.056 0.0453
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.056 0.0446
CCR5 CCR5: CCR5 receptor (Fragment) 0.056 0.202
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.055 0.065
FADD FADD, MORT1: Protein FADD 0.055 0.124
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.055 0.032
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.055 0.052
CD44 N/A 0.055 0.440
TBXA2R TBXA2R: Thromboxane A2 receptor 0.052 0.049
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.052 0.071
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.052 0.225
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.052 0.043
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.052 0.461
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.046
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
RAPH1 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
C9orf88 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
NCAM1 N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
MARK2 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
UBAP2L N/A 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
IGHM N/A 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
HLA-A N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHD N/A 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
TP73 TP73, P73: Tumor protein p73 0.051 0.065
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.126
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.051 0.058
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.051 0.275
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.051 0.088
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.051 0.097
MT3 MT3: Metallothionein-3 0.049 0.037
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.049 0.100
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.202
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.049 0.033
TSC2 TSC2, TSC4: Tuberin 0.049 0.025
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
MAPK15 N/A 0.049 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.028
MAP2K5 N/A 0.049 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
MYO18A 0.049 0.148
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.028
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.049 0.032
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.048 0.166
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.044
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.046 0.045
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
LMO7 N/A 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.046 0.181
RYR1 0.046 0.037
SOS1 SOS1: Son of sevenless homolog 1 0.046 0.181
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.046 0.036
PLEK PLEK, P47: Pleckstrin 0.046 0.561
CENTA1 CENTA1: Centaurin-alpha 1 0.046 0.0794
CDKL5 N/A 0.0453 0.109
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.0453 0.099
RYR2 RYR2: Ryanodine receptor 2 0.045 0.041
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.044 0.111
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.044 0.275
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.111
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.075
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.148
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.148
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.075
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.075
NIPBL N/A 0.044 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.148
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.041 0.090
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.041 0.304
ST6GAL1 ST6GAL1, SIAT1: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltrans 0.041 0.032
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.041 1.07
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.041 0.0727
ST3GAL1 ST3GAL1, SIAT4, SIAT4A: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sia 0.041 0.027
ST8SIA4 ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe 0.041 0.0446
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.064
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.041 0.275
MAGED2 N/A 0.041 0.056
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.041 0.088
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.041 0.225
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.041 0.046
MYO3A MYO3A: Myosin IIIA 0.041 0.099
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.041 0.162
MYH9 MYH9: Myosin-9 0.041 0.304
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.041 0.503
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
COTL1 COTL1, CLP: Coactosin-like protein 0.04 0.025
DSP DSP: Desmoplakin 0.04 0.049
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.083
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.039 0.202
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.072
MARCO MARCO, SCARA2: Macrophage receptor MARCO 0.039 0.025
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.038 0.030
CALCRL CALCRL, CGRPR: Calcitonin gene-related peptide type 1 receptor precursor 0.038 0.029
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.045
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.037 0.123
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.037 0.111
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.037 0.026
FLNA FLNA, FLN, FLN1: Filamin-A 0.037 0.515
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.037 0.171
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.037 0.052
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.037 0.065
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.036 0.036
GSN GSN: Gelsolin precursor 0.036 0.025
CFL2 CFL2: Cofilin-2 0.036 0.025
SVIL SVIL: Supervillin 0.036 0.025
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.035 0.0818
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.035 0.026
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.058
ANXA3 ANXA3, ANX3: Annexin A3 0.034 0.081
TNN TNN: Tenascin-N precursor 0.034 0.042
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.0338 0.265
MAL2 MAL2: Protein MAL2 0.034 0.034
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.069
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.033 0.050
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.033 0.136
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.033 0.225
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.078
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.033 0.097
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.033 0.099
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.136
DYRK3 N/A 0.033 0.088
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.033 0.099
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.033 0.171
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.033 65.60
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.033 0.191
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.033 0.127
HD HD, IT15: Huntingtin 0.033 0.070
FUBP1 N/A 0.033 0.260
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.033 0.852
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.033 0.515
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.033 0.096
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.033 0.111
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.033 0.070
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.033 0.136
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.033 0.090
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.033 0.181
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.033 0.073
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.430
CDK6 CDK6: Cell division protein kinase 6 0.032 0.136
PRKAA1 N/A 0.032 0.191
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.032 0.123
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.144
GAS2 GAS2: Growth arrest-specific protein 2 0.032 0.152
WEE1 WEE1: Wee1-like protein kinase 0.032 0.136
STK16 N/A 0.032 0.251
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.032 0.123
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.307
COBL N/A 0.032 0.088
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.416
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.096
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.031 0.157
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.0308 0.026
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.0308 0.026
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.086
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.034
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.030 0.070
CREB1 CREB1: cAMP response element-binding protein 0.030 0.044
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.098
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.030 0.044
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.044
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.098
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.098
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.030 0.044
CCNT2 CCNT2: Cyclin-T2 0.030 0.044
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.030 0.044
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.030 0.058
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.029 0.233
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.029 0.046
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.029 0.038
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.029 0.275
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.029 0.139
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.029 0.461
HSP90AA1 Hsp89-alpha-delta-N 0.029 0.086
STK10 STK10: Uncharacterized protein STK10 0.029 1.62
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.461
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.029 0.066
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.372
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.029 0.063
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.029 0.139
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.171
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.029 0.763
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.029 0.069
WASPIP N/A 0.029 1.62
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.029 1.62
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.029 0.372
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.029 0.111
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.029 0.763
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.171
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.029 0.129
THOC1 THOC1, HPR1: THO complex subunit 1 0.029 0.114
ATM ATM: Serine-protein kinase ATM 0.029 0.275
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.029 0.063
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.029 0.038
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.029 0.136
CTPS CTPS: CTP synthase 1 0.029 0.029
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.029 0.136
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.029 0.275
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.029 0.191
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.029 0.056
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.029 0.127
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.461
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.461
CDK4 CDK4: Cell division protein kinase 4 0.029 0.171
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.136
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.029 0.056
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.029 0.038
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.029 0.088
KIAA0690 N/A 0.029 0.046
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.029 0.372
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.171
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.038
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.065
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.028 0.049
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.028 0.049
DRD2 DRD2: D(2) dopamine receptor 0.028 0.049
PMP2 PMP2: Myelin P2 protein 0.027 0.044
FGFR2 N/A 0.027 0.217
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
B2M B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro 0.026 0.162
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.026 0.225
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.026 0.044
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.026 0.046
FLII FLII, FLIL: Protein flightless-1 homolog 0.026 0.129
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.026 0.136
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.026 0.763
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.026 0.372
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.026 0.063
CDK5 CDK5: Cell division protein kinase 5 0.026 0.111
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.026 0.136
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.026 0.097
CDK2 CDK2: Cell division protein kinase 2 0.026 0.171
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.026 0.035
CDK7 CDK7, MO15: Cell division protein kinase 7 0.026 0.225
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.026 0.763
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.026 0.078
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.026 0.372
RPS6KB1 N/A 0.026 0.461
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.026 0.155
SYMPK SYMPK, SPK: Symplekin 0.026 0.029
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.372
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.026 0.233
FES N/A 0.0258 0.0258
ETS2 ETS2: Protein C-ets-2 0.025 0.166
ETV1 ETV1, ER81: ETS translocation variant 1 0.025 0.026
TOM1L1 TOM1L1, SRCASM: TOM1-like protein 1 0.025 0.0263
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.0727
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.025 0.044
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.098
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.036
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.098
0.228
Total Score 2.27E4