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Evidence of Interaction Between PDGFRB and FRK

The interaction score between PDGFRB and FRK is 6.35E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between PDGFRB and FRK = -0.06

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology
OrganismPDGFRB OrthologueFRK OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00022296 0.132 IPI00013864 0.079
  • Other
  • InVitro
  • InVivo

Get References From PubMed
human IPI00027721 0.325 IPI00013864 0.079
human IPI00018335 1 IPI00013864 0.079
human IPI00021396 1 IPI00013864 0.079
human IPI00293565 0.322 IPI00013864 0.079
human IPI00005722 0.081 IPI00013864 0.079
worm P34892 0.084 O45539 1
worm O76698 1 O45539 1
worm Q21038 1 O45539 1
worm Q21041 1 O45539 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 1.07
Domains Domains present in PDGFRB and FRK:
Domains in PDGFRBDomains in FRK
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR001452 SH3
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in PDGFRB and FRK are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR008266 Tyrosine protein kinase, active site IPR001452 SH3 164.706
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR001245 Tyrosine protein kinase IPR001452 SH3 100.857
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR003599 Immunoglobulin subtype IPR000980 SH2 motif 66.4833
IPR003598 Immunoglobulin C-2 type IPR000980 SH2 motif 64.7072
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR013151 Immunoglobulin. IPR000980 SH2 motif 36.9251
IPR001824 Receptor tyrosine kinase, class III IPR001452 SH3 32.2626
IPR000719 Protein kinase IPR000719 Protein kinase 30.6895
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR011009 Protein kinase-like IPR011009 Protein kinase-like 26.2215
IPR003598 Immunoglobulin C-2 type IPR001452 SH3 26.0449
IPR003599 Immunoglobulin subtype IPR001452 SH3 22.2905
IPR011009 Protein kinase-like IPR001452 SH3 20.4416
IPR007110 Immunoglobulin-like IPR001452 SH3 20.3228
IPR007110 Immunoglobulin-like IPR011009 Protein kinase-like 16.6203
IPR003598 Immunoglobulin C-2 type IPR008266 Tyrosine protein kinase, active site 15.3939
IPR013151 Immunoglobulin. IPR001452 SH3 14.5395
IPR007110 Immunoglobulin-like IPR000719 Protein kinase 11.3335
IPR008266 Tyrosine protein kinase, active site IPR008266 Tyrosine protein kinase, active site 9.50479
IPR003599 Immunoglobulin subtype IPR011009 Protein kinase-like 8.86948
IPR003599 Immunoglobulin subtype IPR008266 Tyrosine protein kinase, active site 8.71812
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001452 SH3 8.64336
IPR007110 Immunoglobulin-like IPR008266 Tyrosine protein kinase, active site 8.13215
IPR000719 Protein kinase IPR008266 Tyrosine protein kinase, active site 6.98997
IPR003598 Immunoglobulin C-2 type IPR001245 Tyrosine protein kinase 4.5123
IPR001824 Receptor tyrosine kinase, class III IPR008266 Tyrosine protein kinase, active site 4.49385
IPR013151 Immunoglobulin. IPR008266 Tyrosine protein kinase, active site 4.11154
IPR003599 Immunoglobulin subtype IPR000719 Protein kinase 3.60485
IPR000719 Protein kinase IPR011009 Protein kinase-like 2.94434
IPR013151 Immunoglobulin. IPR011009 Protein kinase-like 2.74789
IPR000719 Protein kinase IPR001245 Tyrosine protein kinase 2.31134
IPR013151 Immunoglobulin. IPR000719 Protein kinase 1.81655
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR008266 Tyrosine protein kinase, active site 1.70807
IPR001824 Receptor tyrosine kinase, class III IPR001245 Tyrosine protein kinase 1.57698
IPR003598 Immunoglobulin C-2 type IPR011009 Protein kinase-like 1.32999
IPR003599 Immunoglobulin subtype IPR001245 Tyrosine protein kinase 1.01254
IPR001245 Tyrosine protein kinase IPR008266 Tyrosine protein kinase, active site 0.959759
IPR013151 Immunoglobulin. IPR001245 Tyrosine protein kinase 0.63318
IPR007110 Immunoglobulin-like IPR001245 Tyrosine protein kinase 0.479454
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001245 Tyrosine protein kinase 0.339832
IPR001245 Tyrosine protein kinase IPR011009 Protein kinase-like 0.178275
IPR003598 Immunoglobulin C-2 type IPR000719 Protein kinase 0.142823
IPR001824 Receptor tyrosine kinase, class III IPR011009 Protein kinase-like 0.099805
IPR001245 Tyrosine protein kinase IPR001245 Tyrosine protein kinase 0.0451828
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR011009 Protein kinase-like 0.00926039
IPR008266 Tyrosine protein kinase, active site IPR011009 Protein kinase-like 0.00724826
IPR001824 Receptor tyrosine kinase, class III IPR000719 Protein kinase 0.000102653
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000719 Protein kinase 0.0000462868

The background colour of the table refers to:

  • Blue Domain is only present in PDGFRB
  • Yellow Domain is only present in FRK
  • Green Domain is present in both PDGFRB and FRK

 0.980
Post-translational Modifications

Protein: PDGFRB

PTMResidueReference
Dephosphorylation 562 PubMed, HPRD
Dephosphorylation 579 PubMed, HPRD
Dephosphorylation 740 PubMed, HPRD
Dephosphorylation 751 PubMed, HPRD
Dephosphorylation 771 PubMed, HPRD
Dephosphorylation 857 PubMed, HPRD
Dephosphorylation 1009 PubMed, HPRD
Dephosphorylation 1021 PubMed, HPRD
Phosphorylation 579 PubMed, HPRD
Phosphorylation 581 PubMed, HPRD
Phosphorylation 716 PubMed, HPRD
Phosphorylation 740 PubMed, HPRD
Phosphorylation 751 PubMed, HPRD
Phosphorylation 763 PubMed, HPRD
Phosphorylation 771 PubMed, HPRD
Phosphorylation 775 PubMed, HPRD
Phosphorylation 857 PubMed, HPRD
Phosphorylation 1009 PubMed, HPRD
Phosphorylation 1021 PubMed, HPRD
Phosphotyrosine 751 PubMed, HPRD
Phosphotyrosine 857 PubMed, HPRD

Protein: FRK

PTMResidueReference
Phosphorylation 497 PubMed, HPRD
Localisation

Protein: PDGFRB

LocalisationReference
Plasma membrane HPRD

Protein: FRK

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between PDGFRB and FRK that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PDGFRB andFRK. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PDGFRB has 1323 interactors and FRK has 1283 interactors of which there are 850 common interactors.

Common InteractorName of Common InteractorScore for PDGFRB-Interactor (?)Score for FRK-Interactor (?)
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 1.01E3 1.17
NCK2 NCK2: Cytoplasmic protein NCK2 600.00 0.781
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 600.00 0.874
CRKL CRKL: Crk-like protein 536.00 0.874
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 532.00 0.577
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 422.00 1.17
STAT5B STAT5B: Signal transducer and activator of transcription 5B 372.00 0.577
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 315.00 1.07
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 281.00 1.07
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 281.00 0.770
VAV1 VAV1, VAV: Proto-oncogene vav 281.00 0.770
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 277.00 0.770
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 265.00 0.553
STAT6 STAT6: Signal transducer and activator of transcription 6 250.00 0.874
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 250.00 0.770
HCK N/A 250.00 1.07
JAK2 JAK2: Tyrosine-protein kinase JAK2 250.00 1.35
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 232.00 0.878
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 183.00 0.655
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 147.00 74.90
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 137.00 0.577
GRAP GRAP: GRB2-related adapter protein 133.00 0.156
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 112.00 0.808
KIT KIT: Mast/stem cell growth factor receptor precursor 112.00 0.808
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 84.00 0.097
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 82.20 0.577
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 74.00 1.07
JUP JUP, CTNNG, DP3: Junction plakoglobin 37.90 0.049
SHC2 N/A 29.70 12.40
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 15.80 0.111
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 12.50 0.111
PRKCG PRKCG, PKCG: Protein kinase C gamma type 12.50 0.111
SOCS7 SOCS7, NAP4, SOCS6: Suppressor of cytokine signaling 7 12.40 0.0258
SHC4 SHC-transforming protein 4 2.58 1.07
LOC392481 N/A 2.58 1.07
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 1.13 0.775
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 1.30
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 1.17
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 1.17
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 1.30
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 1.30
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.916 0.049
BMX N/A 0.902 1.20
STAT3 0.878 1.17
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 0.874
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 0.975
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.731 0.775
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.731 0.975
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 0.770
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.654 0.874
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.654 0.975
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.654 1.07
SYK SYK: Tyrosine-protein kinase SYK 0.654 0.874
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.859
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 0.770
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.644 1.50
JAK1 0.644 0.770
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.617
CRK CRK: Proto-oncogene C-crk 0.617 0.617
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.617
GRB10 N/A 0.617 0.617
APS SH2B2, APS: SH2B adapter protein 2 0.586 0.770
LYN LYN: Tyrosine-protein kinase Lyn 0.586 0.874
CSK CSK: Tyrosine-protein kinase CSK 0.586 0.770
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.581 0.975
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 0.859
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.581 0.775
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.581 0.975
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.553
RIN1 RIN1: Ras and Rab interactor 1 0.520 1.35
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.520 0.694
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.372 0.073
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.360 0.731
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.581
STAT2 STAT2: Signal transducer and activator of transcription 2 0.320 0.902
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.318 0.577
STAT4 STAT4: Signal transducer and activator of transcription 4 0.286 0.577
TNC TNC, HXB: Tenascin precursor 0.275 0.064
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.275 0.064
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.251 0.731
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.251 0.072
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.251 0.065
VWF VWF, F8VWF: von Willebrand factor precursor 0.245 0.041
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.245 0.097
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.233 0.064
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.225 0.090
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.265
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.265
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.265
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.265
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.202 0.045
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.202 0.045
CNN3 CNN3: Calponin-3 0.202 0.097
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.202 0.045
SOCS5 SOCS5, CIS6, CISH5, CISH6, KIAA0671: Suppressor of cytokine signaling 5 0.200 0.197
GHR GHR: Growth hormone receptor precursor 0.191 0.081
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.191 0.065
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.081
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.181 0.046
SPARC SPARC, ON: SPARC precursor 0.181 0.046
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.181 0.088
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.181 0.041
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.181 0.046
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.181 0.097
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.171 0.111
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.171 0.586
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.166 0.041
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
KIR3DL1 N/A 0.165 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
FN1 N/A 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.098
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.098
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.878
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
GRB14 GRB14: Growth factor receptor-bound protein 14 0.162 0.197
GRB7 GRB7: Growth factor receptor-bound protein 7 0.162 0.176
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.152 0.731
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.152 0.072
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.152 0.081
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.152 0.072
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.152 0.081
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.152 0.072
DAB2 DAB2, DOC2: Disabled homolog 2 0.148 0.097
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.878
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.878
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.098
BSG N/A 0.148 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.878
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.098
ATRN N/A 0.148 0.044
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.098
SOCS2 SOCS2, CIS2, SSI2, STATI2: Suppressor of cytokine signaling 2 0.145 0.156
SHB SHB: SH2 domain-containing adapter protein B 0.145 0.141
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.143 0.156
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.136 0.577
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.136 0.520
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.136 0.577
INSR INSR: Insulin receptor precursor 0.136 0.655
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.136 0.655
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.136 0.577
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.129 0.174
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.129 0.157
FYN N/A 0.129 0.174
VAV3 VAV3: Protein vav-3 0.128 0.177
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.127 0.032
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.126 0.098
IRS1 IRS1: Insulin receptor substrate 1 0.126 0.109
CTTN CTTN, EMS1: Src substrate cortactin 0.126 2.77
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.125 0.041
PRLR PRLR: Prolactin receptor precursor 0.123 0.100
EGF EGF: Pro-epidermal growth factor precursor 0.123 0.072
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.123 0.081
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.123 0.126
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.081
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.123 0.058
MET MET: Hepatocyte growth factor receptor precursor 0.123 0.581
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.123 0.100
PVR PVR, PVS: Poliovirus receptor precursor 0.123 0.072
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.081
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.081
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.072
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.081
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.123 0.072
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.123 0.100
F3 F3: Tissue factor precursor 0.123 0.072
CHN1 CHN1, ARHGAP2, CHN: N-chimaerin 0.115 0.177
RIN3 N/A 0.115 0.177
CHN2 CHN2, ARHGAP3, BCH: Beta-chimaerin 0.115 0.177
FKBP9 FKBP9, FKBP60, FKBP63: FK506-binding protein 9 precursor 0.114 0.041
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.114 0.033
CHP CHP: Calcium-binding protein p22 0.113 0.097
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.113 0.097
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.112 0.056
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.111 0.041
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.111 0.586
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.111 0.520
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.111 0.073
NEO1 NEO1, NGN: Neogenin precursor 0.111 0.058
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.111 0.577
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.110 0.072
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.110 0.072
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.110 0.072
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.110 0.081
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.110 0.100
SORL1 SORL1: Sortilin-related receptor precursor 0.110 0.073
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.110 0.081
LILRB1 N/A 0.110 0.100
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.110 0.065
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.109 0.148
NF2 NF2, SCH: Merlin 0.109 0.165
PPEF1 N/A 0.109 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.148
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.165
PSCD2 N/A 0.109 0.165
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.148
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
CNN2 CNN2: Calponin-2 0.109 0.148
ITGB4 N/A 0.109 0.072
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.081
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.109 0.081
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.109 0.808
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.100
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.109 0.072
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.109 0.081
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.109 0.081
EPOR EPOR: Erythropoietin receptor precursor 0.109 0.100
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.109 0.072
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.072
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.109 0.081
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.065
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.109 0.100
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.100
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.109 0.081
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.109 0.065
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.109 0.081
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.109 0.072
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.101 0.041
CP CP: Ceruloplasmin precursor 0.100 0.051
F8 F8, F8C: Coagulation factor VIII precursor 0.100 0.051
INHA INHA: Inhibin alpha chain precursor 0.100 0.045
TNNC1 TNNC1, TNNC: Troponin C, slow skeletal and cardiac muscles 0.100 0.037
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.100 0.045
S100A3 S100A3, S100E: Protein S100-A3 0.100 0.123
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.100 0.051
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.099 0.073
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.098 0.109
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.098 0.072
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.065
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.098 0.072
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.072
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.098 0.065
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.081
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.098 0.065
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.065
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.098 0.081
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.098 0.072
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.098 0.072
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.098 0.100
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.098 0.081
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.098 0.081
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.098 0.072
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.098 0.081
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.098 0.100
PTPRZ1 N/A 0.098 0.073
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.148
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.098 0.030
ELMO1 N/A 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.148
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.098 0.030
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.148
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.098 0.025
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
SNX3 N/A 0.098 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.148
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.148
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.098 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
ARHGEF7 N/A 0.098 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.098 0.030
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.148
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.148
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.655
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.097 0.577
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.577
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.073
DCC DCC: Netrin receptor DCC precursor 0.097 0.113
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.096 0.0453
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.096 0.032
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.049
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.090 5.88
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.136
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.090 0.088
MYL3 MYL3: Myosin light polypeptide 3 0.090 0.097
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.097
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.090 0.037
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.088 0.808
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.088 0.073
CD82 CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen 0.088 0.027
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.088 0.073
ITGB7 ITGB7: Integrin beta-7 precursor 0.088 0.029
CRLF3 N/A 0.088 0.081
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.086 0.033
CAV1 CAV1, CAV: Caveolin-1 0.086 0.030
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
EDA N/A 0.083 0.049
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.083 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.049
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.083 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 0.775
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.081 0.123
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.081 0.051
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.081 0.045
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.081 0.123
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.081 0.110
CGA CGA: Glycoprotein hormones alpha chain precursor 0.081 0.045
NDP NDP: Norrin precursor 0.081 0.063
S100A7 S100A7, PSOR1: Protein S100-A7 0.081 0.152
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.081 0.152
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.051
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.081 0.045
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.081 0.123
SPTAN1 N/A 0.081 0.109
CAV2 CAV2: Caveolin-2 0.0782 0.030
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0782 0.0338
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.077 0.037
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.098
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.073 0.088
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.073 0.111
RASA3 RASA3: Ras GTPase-activating protein 3 0.073 0.097
RDX RDX: Radixin 0.073 0.111
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.073 0.136
PLD1 PLD1: Phospholipase D1 0.073 0.111
SORBS3 SORBS3, SCAM1: Vinexin 0.073 0.097
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.073 0.111
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.073 0.111
PLD2 PLD2: Phospholipase D2 0.073 0.136
TTN N/A 0.073 0.111
DLG2 DLG2: Disks large homolog 2 0.073 0.041
TST TST: Thiosulfate sulfurtransferase 0.073 0.097
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.073 0.097
SH3BP5 N/A 0.073 0.088
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.073 0.111
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.073 0.171
TLN2 TLN2: Uncharacterized protein TLN2 0.073 0.136
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.0727 0.123
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.0727 0.111
ROCK1 ROCK1: Rho-associated protein kinase 1 0.0727 0.123
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0727 0.123
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.109
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.072 0.063
S100B S100B: Protein S100-B 0.072 0.152
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.072 0.191
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.072 0.051
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.097
IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 0.072 0.051
GRLF1 N/A 0.072 0.109
TSHB TSHB: Thyrotropin subunit beta precursor 0.072 0.045
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.109
FSHB FSHB: Follitropin subunit beta precursor 0.072 0.045
F5 F5: Coagulation factor V precursor 0.072 0.063
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.072 0.037
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.072 0.111
IRS2 IRS2: Insulin receptor substrate 2 0.072 0.191
LHB LHB: Lutropin subunit beta precursor 0.072 0.045
GAB1 GAB1: GRB2-associated-binding protein 1 0.072 0.191
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.072 0.045
NSBP1 NSBP1: Nucleosome-binding protein 1 0.0688 0.109
CETN1 CETN1, CEN1, CETN: Centrin-1 0.0688 0.098
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.065 0.136
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.065 0.111
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.065 5.88
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.065 0.136
LCP1 LCP1, PLS2: Plastin-2 0.065 0.111
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.065 0.111
CXorf9 N/A 0.065 0.097
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.065 0.136
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.065 0.136
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.065 0.097
GMIP GMIP: GEM-interacting protein 0.065 0.111
PSCD4 PSCD4, CYT4: Cytohesin-4 0.065 0.111
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.065 5.88
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.065 0.111
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.065 0.111
CD2AP CD2AP: CD2-associated protein 0.065 0.097
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.065 0.171
FNBP1 N/A 0.065 3.14
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.123
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.065 0.152
GAB2 N/A 0.065 0.191
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.065 0.123
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.065 0.152
VASP VASP: Vasodilator-stimulated phosphoprotein 0.065 0.123
SNCB SNCB: Beta-synuclein 0.065 0.123
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.065 0.111
CSPG2 N/A 0.065 0.0794
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.065 0.111
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.065 0.037
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.065 0.063
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.065 0.152
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.065 0.123
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.064 0.071
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.064 0.057
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.136
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.064 0.088
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.064 0.097
TLN1 TLN1: Uncharacterized protein TLN1 0.064 0.111
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.064 0.111
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.046
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.558
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.064 0.097
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.064 0.057
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.064 0.136
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.064 0.136
VIL2 N/A 0.064 0.088
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.097
FGF9 FGF9: Glia-activating factor precursor 0.064 0.046
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.064 0.097
DAB1 DAB1: Disabled homolog 1 0.064 0.171
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.064 0.046
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.081
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.062 0.072
HPN HPN, TMPRSS1: Serine protease hepsin 0.062 0.029
RHO RHO, OPN2: Rhodopsin 0.062 0.037
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.062 0.032
GABRR1 N/A 0.062 0.037
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.062 0.037
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.098
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.098
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.061 0.045
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.060 0.145
CNN1 CNN1: Calponin-1 0.059 0.0273
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.058 0.136
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.058 0.111
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.058 0.111
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.058 25.20
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.058 0.097
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.058 0.046
FGL2 FGL2: Fibroleukin precursor 0.058 0.028
PSD TYL: TYL protein 0.058 0.097
MSN MSN: Moesin 0.058 0.111
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.058 0.097
DOK1 DOK1: Docking protein 1 0.058 0.111
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.058 0.088
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.058 0.111
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.058 0.111
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.058 0.111
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.058 0.097
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.058 0.097
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.058 0.123
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.056 0.026
GLRA1 N/A 0.056 0.033
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.056 0.065
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.056 0.051
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.090
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.056 0.065
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.056 0.072
ATP2B1 N/A 0.056 0.037
CCR5 CCR5: CCR5 receptor (Fragment) 0.056 0.081
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.055 0.126
FADD FADD, MORT1: Protein FADD 0.055 0.032
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.055 0.037
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.055 0.100
CD44 N/A 0.055 0.037
DSTN DSTN, ACTDP, DSN: Destrin 0.054 0.028
SDC4 SDC4: Syndecan-4 precursor 0.054 0.026
TBXA2R TBXA2R: Thromboxane A2 receptor 0.052 0.04
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.052 0.04
STMN1 STMN1, LAP18, OP18: Stathmin 0.052 0.111
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.052 0.111
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.052 0.136
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.052 0.136
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.052 0.111
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.046
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
KIAA1688 KIAA1688: KIAA1688 protein (Fragment) 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
RAPH1 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
PPP1R14C PPP1R14C, KEPI: Protein phosphatase 1 regulatory subunit 14C 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
C9orf88 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
NCAM1 N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
MARK2 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
UBAP2L N/A 0.051 0.051
ITIH3 ITIH3: Inter-alpha-trypsin inhibitor heavy chain H3 precursor 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
PPP1R1B PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
IGHM N/A 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
NF1 NF1: Neurofibromin 0.051 0.046
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
HLA-A N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHD N/A 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
SPARCL1 SPARCL1: SPARC-like protein 1 precursor 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
SNX12 N/A 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
SNX2 SNX2, TRG9: Sorting nexin-2 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
TP73 TP73, P73: Tumor protein p73 0.051 0.100
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.081
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.051 0.072
SALF GTF2A1L, ALF, GTF2A1LF: TFIIA-alpha and beta-like factor 0.0513 0.037
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.051 0.097
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.051 0.111
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.051 0.088
MT3 MT3: Metallothionein-3 0.049 0.0416
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.049 0.126
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.065
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.049 0.037
TSC2 TSC2, TSC4: Tuberin 0.049 0.075
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
MAPK15 N/A 0.049 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.083
MAP2K5 N/A 0.049 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
MYO18A 0.049 0.025
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.083
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.049 0.033
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.048 0.030
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.047 0.038
AQP4 AQP4: Aquaporin-4 0.047 0.036
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.044
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.046 0.045
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
LMO7 N/A 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
PPP1R14A PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A 0.046 0.046
MLLT4 N/A 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
FKBP10 FKBP10, FKBP65, PSEC0056: FK506-binding protein 10 precursor 0.046 0.041
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.046 0.064
RYR1 0.046 0.046
SOS1 SOS1: Son of sevenless homolog 1 0.046 0.064
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.046 0.072
PLEK PLEK, P47: Pleckstrin 0.046 0.081
CENTA1 CENTA1: Centaurin-alpha 1 0.046 0.063
CDKL5 N/A 0.0453 0.109
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.0453 0.097
RYR2 RYR2: Ryanodine receptor 2 0.045 0.051
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.044 0.029
GLRB GLRB: Glycine receptor subunit beta precursor 0.044 0.033
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.044 0.097
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.097
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.075
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.148
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.148
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.075
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.075
NIPBL N/A 0.044 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.148
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.041 0.073
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.041 0.090
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.041 0.073
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.041 0.081
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.073
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.041 0.097
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.041 0.111
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.041 0.136
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.041 0.037
MYO3A MYO3A: Myosin IIIA 0.041 0.111
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.041 0.143
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.041 0.090
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.052
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
COTL1 COTL1, CLP: Coactosin-like protein 0.04 0.047
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.083
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.039 0.037
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.0263
SDC1 SDC1, SDC: Syndecan-1 precursor 0.039 0.032
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.039 0.032
GJA5 GJA5: Gap junction alpha-5 protein 0.038 0.038
PPP1R1A PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A 0.038 0.0338
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.038 0.038
PPP1R14D PPP1R14D, GBPI: Protein phosphatase 1 regulatory subunit 14D 0.038 0.034
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.045
NPPC NPPC, CNP2: C-type natriuretic peptide precursor [Contains: CNP-22; CNP-29; CNP- 0.037 0.025
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.037 0.123
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.037 0.077
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.037 0.073
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.037 0.073
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.036 0.072
GSN GSN: Gelsolin precursor 0.036 0.047
CFL2 CFL2: Cofilin-2 0.036 0.047
SVIL SVIL: Supervillin 0.036 0.047
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.035 0.033
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.035 0.033
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.073
TNN TNN: Tenascin-N precursor 0.034 0.042
PEBP1 PEBP1, PBP, PEBP: Phosphatidylethanolamine-binding protein 1 0.034 0.030
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.0338 0.0338
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.0338 0.047
BID BID: BH3-interacting domain death agonist 0.034 0.049
MAL2 MAL2: Protein MAL2 0.034 0.034
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.044
AQP1 AQP1, CHIP28: Aquaporin-1 0.033 0.035
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.033 0.056
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.033 0.171
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.033 0.097
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.097
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.033 0.097
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.033 0.097
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.097
DYRK3 N/A 0.033 0.111
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.033 0.097
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.033 0.136
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.033 0.097
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.033 0.123
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.033 0.062
HD HD, IT15: Huntingtin 0.033 0.077
FUBP1 N/A 0.033 0.055
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.033 0.123
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.033 0.123
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.033 0.055
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.033 0.097
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.033 0.026
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.033 0.111
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.033 0.090
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.033 0.073
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.033 0.073
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.055
CDK6 CDK6: Cell division protein kinase 6 0.032 0.136
PRKAA1 N/A 0.032 0.109
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.032 0.123
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.062
GAS2 GAS2: Growth arrest-specific protein 2 0.032 0.026
WEE1 WEE1: Wee1-like protein kinase 0.032 0.097
STK16 N/A 0.032 0.109
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.032 0.109
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.109
COBL N/A 0.032 0.123
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.109
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.049
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.031 0.027
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.0308 0.026
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.0308 0.033
CDC37 CDC37: Hsp90 co-chaperone Cdc37 0.031 0.034
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.030 0.042
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.042
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.034
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.030 0.0273
C1QBP C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot 0.030 0.030
CREB1 CREB1: cAMP response element-binding protein 0.030 0.044
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.098
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.030 0.044
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.044
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.098
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.098
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.030 0.044
CCNT2 CCNT2: Cyclin-T2 0.030 0.044
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.030 0.044
CHAT CHAT: Choline O-acetyltransferase 0.030 0.030
DBN1 DBN1, D0S117E: Drebrin 0.030 0.034
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.030 0.033
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.029 0.056
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.029 0.049
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.029 0.049
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.029 0.056
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.029 0.097
HSP90AA1 Hsp89-alpha-delta-N 0.029 0.069
STK10 STK10: Uncharacterized protein STK10 0.029 0.097
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.111
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.029 0.033
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.111
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.029 0.049
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.029 0.056
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.097
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.029 0.056
WASPIP N/A 0.029 5.18
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.029 0.111
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.029 0.136
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.029 0.136
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.029 0.111
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.097
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.029 0.056
THOC1 THOC1, HPR1: THO complex subunit 1 0.029 0.056
ATM ATM: Serine-protein kinase ATM 0.029 0.097
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.029 0.056
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.029 0.056
CTPS CTPS: CTP synthase 1 0.029 0.056
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.029 0.136
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.029 0.111
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.029 0.123
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.029 0.049
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.097
PVALB PVALB: Parvalbumin alpha 0.029 0.051
TNNC2 TNNC2: Troponin C, skeletal muscle 0.029 0.0416
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.111
CDK4 CDK4: Cell division protein kinase 4 0.029 0.111
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.136
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.029 0.044
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.029 0.097
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.029 0.111
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.097
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.090
SYK N/A 0.0288 0.0288
TNS1 TNS1, TNS: Tensin-1 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
DAPP1 DAPP1, BAM32, HSPC066: Dual adapter for phosphotyrosine and 3-phosphotyrosine an 0.0288 0.0288
VAV3 VAV-like protein (Fragment) 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
PIK3R1 PIK3R1, GRB1: Phosphatidylinositol 3-kinase regulatory subunit alpha 0.0288 0.0288
PIK3R3 PIK3R3: Phosphatidylinositol 3-kinase regulatory subunit gamma 0.0288 0.0288
FGR FGR, RP1-159A19.2-007: Gardner-Rasheed feline sarcoma viral (Fragment) 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
INPP5D N/A 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
BTK N/A 0.0288 0.0288
TENC1 N/A 0.0288 0.0288
SOCS6 SOCS6, CIS4, SOCS4: Suppressor of cytokine signaling 6 0.0288 0.0288
GRB10 Adapter protein (Fragment) 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
BLNK BLNK, SLP65, BASH: B-cell linker protein (Fragment) 0.0288 0.0288
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SLC4A1 SLC4A1, AE1, DI, EPB3: Band 3 anion transport protein 0.028 0.033
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.028 0.033
SPOCK2 SPOCK2, KIAA0275, UNQ269/PRO306, TICN2: Testican-2 precursor 0.0273 0.030
EIF4EBP1 EIF4EBP1: Eukaryotic translation initiation factor 4E-binding protein 1 0.0273 0.030
PMP2 PMP2: Myelin P2 protein 0.027 0.069
AQP2 AQP2: Aquaporin-2 0.027 0.028
FGFR2 N/A 0.027 0.217
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 0.0263 0.034
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.026 0.111
FLII FLII, FLIL: Protein flightless-1 homolog 0.026 0.0308
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.026 0.097
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.026 0.111
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.026 0.171
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.026 0.056
CDK5 CDK5: Cell division protein kinase 5 0.026 0.136
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.026 0.111
CDK2 CDK2: Cell division protein kinase 2 0.026 0.111
CDK7 CDK7, MO15: Cell division protein kinase 7 0.026 0.097
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.026 0.111
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.026 0.111
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.026 0.111
RPS6KB1 N/A 0.026 0.111
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.026 0.041
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.111
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.026 0.049
INPPL1 INPPL1, SHIP2: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 0.0258 0.0258
FES N/A 0.0258 0.0258
ETS2 ETS2: Protein C-ets-2 0.025 0.100
ETV1 ETV1, ER81: ETS translocation variant 1 0.025 0.037
TOM1L1 TOM1L1, SRCASM: TOM1-like protein 1 0.025 0.032
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.072
CFTR CFTR: Cystic fibrosis transmembrane conductance regulator ATP-binding cassette s 0.025 0.025
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.098
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.044
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.044
0.572
Total Score 6.35E4