PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between STAT5B and CREBBP

The interaction score between STAT5B and CREBBP is 1.55E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between STAT5B and CREBBP = 0.61

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

7.78E-3

Orthology

Organism	STAT5B Orthologue		CREBBP Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
human	IPI00000106	0.075	IPI00478752	0.421
human	IPI00298887	0.082	IPI00478752	0.421	InVitro InVivo Immunoprecipitation Get References From PubMed
worm	Q9NAD6	1	P34545	0.421
fly	Q24151	1	O01368	0.385

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

1.07

Domains

Domains present in STAT5B and CREBBP:

Domains in STAT5B

Domains in CREBBP

IPR008967	p53-like transcription factor, DNA-binding
IPR000980	SH2 motif
IPR001217	STAT protein
IPR011992	EF-Hand_type.
IPR012345	STAT_DNA_bd.

IPR001487	Bromodomain
IPR000197	TAZ finger
IPR000433	Zn-finger, ZZ type
IPR003101	Coactivator CBP, KIX
IPR009255	Protein of unknown function DUF906
IPR010303	Protein of unknown function DUF902

The Chi square scores for co-occurrence of domains that are present in STAT5B and CREBBP are listed below.

Domain 1		Domain 2		Chi Square
IPR000980	SH2 motif	IPR001487	Bromodomain	5.72482
IPR001217	STAT protein	IPR010303	Protein of unknown function DUF902	3.9426
IPR012345	STAT_DNA_bd.	IPR009255	Protein of unknown function DUF906	3.9426
IPR001217	STAT protein	IPR009255	Protein of unknown function DUF906	3.9426
IPR012345	STAT_DNA_bd.	IPR003101	Coactivator CBP, KIX	3.9426
IPR001217	STAT protein	IPR003101	Coactivator CBP, KIX	3.9426
IPR012345	STAT_DNA_bd.	IPR010303	Protein of unknown function DUF902	3.9426
IPR012345	STAT_DNA_bd.	IPR000197	TAZ finger	3.9426
IPR001217	STAT protein	IPR000197	TAZ finger	3.9426
IPR001217	STAT protein	IPR001487	Bromodomain	2.00418
IPR012345	STAT_DNA_bd.	IPR001487	Bromodomain	2.00418
IPR000980	SH2 motif	IPR000433	Zn-finger, ZZ type	1.96312
IPR001217	STAT protein	IPR000433	Zn-finger, ZZ type	1.56898
IPR012345	STAT_DNA_bd.	IPR000433	Zn-finger, ZZ type	1.56898
IPR011992	EF-Hand_type.	IPR001487	Bromodomain	0.804602
IPR011992	EF-Hand_type.	IPR000433	Zn-finger, ZZ type	0.765888
IPR000980	SH2 motif	IPR000197	TAZ finger	0.612223
IPR000980	SH2 motif	IPR010303	Protein of unknown function DUF902	0.612223
IPR000980	SH2 motif	IPR003101	Coactivator CBP, KIX	0.612223
IPR000980	SH2 motif	IPR009255	Protein of unknown function DUF906	0.612223
IPR011992	EF-Hand_type.	IPR009255	Protein of unknown function DUF906	0.0563285
IPR011992	EF-Hand_type.	IPR000197	TAZ finger	0.0563285
IPR011992	EF-Hand_type.	IPR010303	Protein of unknown function DUF902	0.0563285
IPR011992	EF-Hand_type.	IPR003101	Coactivator CBP, KIX	0.0563285

The background colour of the table refers to:

Blue Domain is only present in STAT5B
Yellow Domain is only present in CREBBP
Green Domain is present in both STAT5B and CREBBP

0.083

Post-translational Modifications

Protein: STAT5B

PTM	Residue	Reference
Dephosphorylation	699	PubMed, HPRD
Phosphorylation	679	PubMed, HPRD
Phosphorylation	699	PubMed, HPRD
Phosphorylation	725	PubMed, HPRD
Phosphorylation	731	PubMed, HPRD
Phosphorylation	740	PubMed, HPRD
Phosphorylation	743	PubMed, HPRD

Protein: CREBBP

PTM	Residue	Reference
Methylation	702	PubMed, HPRD
Methylation	714	PubMed, HPRD
Methylation	742	PubMed, HPRD
Methylation	768	PubMed, HPRD
Phosphorylation	302	PubMed, HPRD
Phosphorylation	437	PubMed, HPRD

Localisation

Protein: STAT5B

Localisation	Reference
Nucleus	HPRD
Cytoplasm	HPRD

Protein: CREBBP

Localisation	Reference
Nucleus	HPRD

Transitive Score

The common interactors between STAT5B and CREBBP that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between STAT5B andCREBBP. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , STAT5B has 1726 interactors and CREBBP has 1102 interactors of which there are 876 common interactors.

Common Interactor	Name of Common Interactor	Score for STAT5B-Interactor (?)	Score for CREBBP-Interactor (?)
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	409.00	77.30
STAT6	STAT6: Signal transducer and activator of transcription 6	330.00	66.00
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	199.00	35.90
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	90.40	0.087
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	53.10	0.029
STAT4	STAT4: Signal transducer and activator of transcription 4	23.50	0.086
MAP2K3	N/A	12.00	0.025
PIAS1	PIAS1, DDXBP1: E3 SUMO-protein ligase PIAS1	8.87	1.61
STAT3		8.34	0.044
PIAS4	PIAS4, PIASG: E3 SUMO-protein ligase PIAS4	5.36	0.741
RELB	RELB: Transcription factor RelB	4.07	5.36
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	2.73	0.032
CSK	CSK: Tyrosine-protein kinase CSK	2.20	0.032
LYN	LYN: Tyrosine-protein kinase Lyn	1.62	0.032
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	1.33	0.067
GATA3	GATA3: Trans-acting T-cell-specific transcription factor GATA-3	1.19	0.741
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	0.975	0.032
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.878	0.044
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.852	0.416
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	0.808	0.033
BMX	N/A	0.644	0.032
GATA5	GATA5: Transcription factor GATA-5	0.642	0.642
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.515	0.060
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.515	0.087
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.515	0.0971
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.503	0.040
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.471	0.344
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.461	0.188
STK10	STK10: Uncharacterized protein STK10	0.461	0.063
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.461	0.233
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.461	0.063
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.461	0.139
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.461	0.063
IRF3	IRF3: Interferon regulatory factor 3	0.416	0.307
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.416	0.096
ATM	ATM: Serine-protein kinase ATM	0.372	0.038
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.372	0.046
CXorf9	N/A	0.372	0.046
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.372	0.063
RPS6KB1	N/A	0.372	0.046
MYH9	MYH9: Myosin-9	0.372	0.275
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.372	0.063
SOS1	SOS1: Son of sevenless homolog 1	0.372	0.139
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.372	0.139
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.372	0.063
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.372	0.046
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.372	0.139
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.372	0.046
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.372	0.275
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.372	0.038
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.372	0.046
SLA	SLA, SLAP, SLAP1: SRC-like-adapter	0.340	0.0446
EPHB3	EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor	0.318	0.041
PLEK	PLEK, P47: Pleckstrin	0.307	0.155
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.307	0.0425
ROCK1	ROCK1: Rho-associated protein kinase 1	0.307	0.155
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.307	0.052
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.304	0.032
WASPIP	N/A	0.304	0.040
ARHGEF6	ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6	0.304	0.111
MSN	MSN: Moesin	0.304	0.090
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.284	0.158
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.275	0.139
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.275	0.225
ELMO2	ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2	0.275	0.188
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.275	0.046
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.275	0.046
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.275	0.063
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.275	0.071
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.275	0.038
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.275	0.063
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.275	0.046
FNBP1	N/A	0.275	0.063
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.275	0.038
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.275	0.046
DOK1	DOK1: Docking protein 1	0.275	0.139
PSTPIP1	PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1	0.274	0.036
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.274	0.036
VASP	VASP: Vasodilator-stimulated phosphoprotein	0.274	0.101
ELF1	ELF1: ETS-related transcription factor Elf-1	0.260	0.416
GAB2	N/A	0.251	0.127
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.251	0.0425
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.251	0.210
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.251	0.032
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.251	0.0425
PSCD4	PSCD4, CYT4: Cytohesin-4	0.245	0.0818
VAV1	VAV1, VAV: Proto-oncogene vav	0.245	0.111
LCP1	LCP1, PLS2: Plastin-2	0.245	0.245
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.245	0.0818
WAS	WAS, IMD2: Wiskott-Aldrich syndrome protein	0.245	0.112
OSBP	OSBP, OSBP1: Oxysterol-binding protein 1	0.245	0.067
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.233	0.063
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.233	0.063
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.233	0.046
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.233	0.063
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.225	0.038
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.225	0.029
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.225	0.038
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.225	0.038
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.225	0.046
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	0.225	0.046
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.225	0.046
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	0.225	0.038
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.225	0.038
SGK3	SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3	0.225	0.038
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.210	0.251
NBN	NBN, NBS, NBS1, P95: Nibrin	0.210	0.210
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.210	0.0425
NCF1	Neutrophil cytosolic factor 1 variant (Fragment)	0.202	0.036
PLCG1	PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	0.202	0.057
SH3BP2	SH3BP2: Uncharacterized protein SH3BP2	0.202	0.091
IRS2	IRS2: Insulin receptor substrate 2	0.191	0.127
ETS2	ETS2: Protein C-ets-2	0.191	0.191
STK16	N/A	0.191	0.032
STAT2	STAT2: Signal transducer and activator of transcription 2	0.191	0.096
PRKAA1	N/A	0.191	0.032
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.191	0.0425
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.191	0.032
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.188	0.118
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.188	0.078
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.188	0.046
JUND	JUND: Transcription factor jun-D	0.188	0.372
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.188	0.038
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.188	0.038
ETS1	ETS1, EWSR2: Protein C-ets-1	0.188	0.225
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.188	0.046
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.188	0.046
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.188	0.046
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.188	0.038
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.188	0.038
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.188	0.188
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.188	0.046
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.188	0.046
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.188	0.078
RELA	RELA, NFKB3: Transcription factor p65	0.188	0.188
JUNB	JUNB: Transcription factor jun-B	0.188	0.275
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.188	0.275
IQGAP1	IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1	0.181	0.111
NCK2	NCK2: Cytoplasmic protein NCK2	0.181	0.032
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.181	11.40
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	0.181	0.0818
SGK	SGK, SGK1: Serine/threonine-protein kinase Sgk1	0.171	0.038
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.171	0.038
MAP3K11	MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11	0.171	0.029
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.171	0.038
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.171	0.038
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.171	0.029
FLNA	FLNA, FLN, FLN1: Filamin-A	0.166	0.202
LIMK2	LIMK2: LIM domain kinase 2	0.166	0.075
MAPK15	N/A	0.165	0.028
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.165	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.165	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.165	0.028
MAPKAPK5	N/A	0.165	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.165	0.028
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.165	0.028
PPEF1	N/A	0.165	0.083
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.165	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.165	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.165	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.165	0.028
NF2	NF2, SCH: Merlin	0.165	0.052
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.156	0.137
H1FX	H1FX: Histone H1x	0.155	0.251
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.155	0.307
DDX21	DDX21: Nucleolar RNA helicase 2	0.155	0.0425
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.155	0.096
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.155	0.052
XRCC1	XRCC1: DNA-repair protein XRCC1	0.155	0.0425
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.155	0.127
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.155	0.0425
BACH1	BACH1: Transcription regulator protein BACH1	0.155	0.416
SP100	N/A	0.155	0.307
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.155	0.307
NFATC1	N/A	0.155	0.127
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.155	0.251
FUBP1	N/A	0.153	0.027
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.152	0.152
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.152	0.032
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.152	0.026
GAB1	GAB1: GRB2-associated-binding protein 1	0.152	0.077
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.152	0.152
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.152	0.026
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.152	0.026
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.152	0.026
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.152	0.127
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.152	0.026
VIL2	N/A	0.148	0.054
RASA3	RASA3: Ras GTPase-activating protein 3	0.148	0.041
PLCB3	PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3	0.148	0.051
IQSEC1	IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein	0.148	0.0818
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.148	0.041
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.148	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.148	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.148	0.025
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.148	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.148	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.148	0.025
ELMO1	N/A	0.148	0.075
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.148	0.025
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.148	0.025
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.148	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.148	0.075
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.148	0.025
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.148	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.148	0.025
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.148	0.025
EEF2K	EEF2K: Elongation factor 2 kinase	0.148	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.148	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.148	0.025
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.148	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.148	0.025
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.148	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.148	0.075
CDC2	CDC2: Cell division control protein 2 homolog	0.148	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.148	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.148	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.148	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.148	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.148	0.025
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.148	0.025
YY1	YY1: Transcriptional repressor protein YY1	0.146	0.188
SP3	SP3: Transcription factor Sp3	0.146	0.233
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.146	0.188
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.146	0.188
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.139	0.275
HDAC3	HDAC3: Histone deacetylase 3	0.139	0.071
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.139	0.038
MLL	MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX	0.139	0.114
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.139	0.029
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.139	0.114
BRPF1	BRPF1, BR140: Peregrin	0.139	0.114
HDAC4	HDAC4, KIAA0288: Histone deacetylase 4	0.139	0.046
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.139	0.038
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.139	0.029
AIP	AIP, XAP2: AH receptor-interacting protein	0.139	0.046
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.139	0.372
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.139	0.087
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.139	0.038
ATF6	ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha	0.139	0.275
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.137	0.032
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.137	0.137
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.136	0.029
DAB2	DAB2, DOC2: Disabled homolog 2	0.136	0.035
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.136	0.054
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.132	0.210
ARFGAP1	N/A	0.132	0.0425
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.132	0.052
RB1	RB1: Retinoblastoma-associated protein	0.127	0.0425
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.127	0.0425
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.127	0.096
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.127	0.060
SQSTM1	SQSTM1: Uncharacterized protein SQSTM1	0.126	0.057
TRADD	TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein	0.124	0.074
LIMS1	N/A	0.124	0.027
DAPK2	DAPK2: Death-associated protein kinase 2	0.123	0.026
ICK	ICK, KIAA0936: Serine/threonine-protein kinase ICK	0.123	0.026
NEK3	NEK3: Serine/threonine-protein kinase Nek3	0.123	0.026
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.118	0.114
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.118	0.188
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.118	0.029
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.118	0.086
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.118	0.063
TRIM25	TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25	0.114	0.086
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.114	0.225
TP53	TP53, P53: Cellular tumor antigen p53	0.114	0.086
CEBPB	CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta	0.114	0.225
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.114	0.171
NFKBIA	NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha	0.114	0.038
CCNH	CCNH: Cyclin-H	0.114	0.029
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.114	0.038
HDAC2	HDAC2: Histone deacetylase 2	0.114	0.054
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.114	0.038
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.114	0.029
FOXO1A	FOXO1A, FKHR: Forkhead box protein O1A	0.114	0.171
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.114	0.097
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.113	0.033
EHD1	EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1	0.112	0.137
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.112	0.111
GMIP	GMIP: GEM-interacting protein	0.111	0.032
RAPGEF6	RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6	0.111	0.067
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.111	0.032
ACTR3	ACTR3, ARP3: Actin-related protein 3	0.111	0.111
PPP1CB	PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit	0.111	0.032
RGS19	RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19	0.111	0.032
APBA2	APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2	0.111	0.056
TIAM1	TIAM1: T-lymphoma invasion and metastasis-inducing protein 1	0.111	0.069
PSCD2	N/A	0.109	0.049
DNM3	DNM3: Uncharacterized protein DNM3	0.109	0.049
CNN2	CNN2: Calponin-2	0.109	0.049
PSCD1	PSCD1, D17S811E: Cytohesin-1	0.109	0.049
LNK	SH2B3, LNK: SH2B adapter protein 3	0.109	0.049
ITSN1	ITSN1, ITSN, SH3D1A: Intersectin-1	0.109	0.049
IRS1	IRS1: Insulin receptor substrate 1	0.109	0.062
GRK1	GRK1, RHOK: Rhodopsin kinase precursor	0.109	0.026
PLEKHA5	PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member	0.109	0.062
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.109	0.055
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.100	0.0453
ROCK2	ROCK2, KIAA0619: Rho-associated protein kinase 2	0.099	0.049
ARHGEF12	ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12	0.098	0.055
TP73	TP73, P73: Tumor protein p73	0.098	0.031
MYO18A		0.098	0.044
EPB41L1	EPB41L1, KIAA0338: Band 4.1-like protein 1	0.098	0.036
ARHGEF7	N/A	0.098	0.044
SPTBN1	SPTBN1, SPTB2: Spectrin beta chain, brain 1	0.098	0.098
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.098	0.044
ITSN2	ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2	0.098	0.044
ACTN4	ACTN4: Alpha-actinin-4	0.098	0.098
RASA1	RASA1, RASA: Ras GTPase-activating protein 1	0.098	0.044
DAB1	DAB1: Disabled homolog 1	0.097	0.028
CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL	0.097	0.049
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.097	0.029
MATR3	MATR3, KIAA0723: Matrin-3	0.0971	0.127
ZNF267	ZNF267: Zinc finger protein 267	0.0971	0.307
ERF	ERF: ETS domain-containing transcription factor ERF	0.096	0.191
ERG	ERG: Transcriptional regulator ERG	0.096	0.123
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.096	0.123
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.096	0.251
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.096	0.026
VIM	VIM: Vimentin	0.096	0.026
SLC9A3R1	SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50	0.091	0.091
MICAL-L1	MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1	0.090	0.051
ARHGAP12	ARHGAP12: Rho GTPase-activating protein 12	0.090	0.051
PLD2	PLD2: Phospholipase D2	0.090	0.051
ACTN1	ACTN1: Alpha-actinin-1	0.090	0.113
MAPRE2	MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2	0.090	0.051
APS	SH2B2, APS: SH2B adapter protein 2	0.090	0.067
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.087	0.210
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.087	0.052
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.087	0.114
ZNF335	ZNF335: Zinc finger protein 335	0.087	0.114
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.087	0.114
MTF1	MTF1: Metal regulatory transcription factor 1	0.087	0.139
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.086	0.038
CEBPE	CEBPE: CCAAT/enhancer-binding protein epsilon	0.086	0.136
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.086	0.225
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.086	0.097
JUN	JUN: Transcription factor AP-1	0.086	0.225
PCAF	PCAF: Histone acetyltransferase PCAF	0.086	0.054
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.086	0.171
MAFG	MAFG: Transcription factor MafG	0.086	0.171
FOS	FOS, G0S7: Proto-oncogene protein c-fos	0.086	0.225
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.086	0.136
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.083	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.083	0.028
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.083	0.165
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.083	0.165
HDAC8	N/A	0.083	0.052
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.083	0.165
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.083	0.083
DSP	DSP: Desmoplakin	0.083	0.165
HES6	HES6: Transcription cofactor HES-6	0.083	0.083
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.083	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.083	0.083
RNF31	ISGF3G, IRF9: Transcriptional regulator ISGF3 subunit gamma	0.083	0.083
IRF1	IRF1: Interferon regulatory factor 1	0.083	0.083
ACTG1	ACTB: Actin, cytoplasmic 1	0.0818	39.30
THOC1	THOC1, HPR1: THO complex subunit 1	0.0818	0.041
PDLIM1	PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1	0.081	0.037
SPTA1	SPTA1, SPTA: Spectrin alpha chain, erythrocyte	0.081	0.081
IRS4	IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4	0.081	0.037
ZFX	ZFX: Zinc finger X-chromosomal protein	0.080	0.096
HIVEP1	N/A	0.080	0.127
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.080	0.251
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.080	0.127
MAPK8IP1	MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1	0.078	0.028
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.078	0.046
PHF10	N/A	0.078	0.114
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.078	0.063
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.078	0.046
DIAPH1	Diaphanous 1	0.078	0.063
WBSCR20A	N/A	0.078	0.046
EP300	N/A	0.078	0.063
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.078	0.063
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.078	0.275
GTF2F2	N/A	0.077	0.152
ZYX	ZYX: Zyxin	0.075	0.027
RGS2	RGS2, G0S8: Regulator of G-protein signaling 2	0.075	0.027
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.075	0.075
S100A9	S100A9, CAGB, CFAG, MRP14: Protein S100-A9	0.075	0.075
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.075	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.075	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.075	0.075
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.075	0.148
HDAC7A	N/A	0.075	0.025
GIT2	N/A	0.075	0.025
CREB1	CREB1: cAMP response element-binding protein	0.075	0.148
BRD4	N/A	0.075	0.047
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.075	0.148
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.075	0.025
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.075	0.148
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.075	0.025
CCNT2	CCNT2: Cyclin-T2	0.075	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.075	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.075	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.075	0.025
ALOX5	ALOX5, LOG5: Arachidonate 5-lipoxygenase	0.074	0.036
MVP	MVP, LRP: Major vault protein	0.074	0.027
CASP8	N/A	0.074	0.036
WASL	WASL: Neural Wiskott-Aldrich syndrome protein	0.073	0.027
FLNB	FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B	0.073	0.073
CNN3	CNN3: Calponin-3	0.0727	0.032
GAS2	GAS2: Growth arrest-specific protein 2	0.072	0.032
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.071	0.029
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.071	0.029
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.071	0.136
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.071	0.114
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.071	0.029
TGFBR1	TGFBR1: TGF-beta receptor type-1 precursor	0.071	0.035
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.070	0.052
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.070	0.052
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.070
TOP2B	N/A	0.070	0.052
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.070	0.052
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.070	0.0425
KIAA0853	N/A	0.070	0.052
RBM14	RBM14, SIP: RNA-binding protein 14	0.070	0.052
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.070	0.052
DNMT1	DNMT1, AIM, DNMT: DNA	0.070	0.0425
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.052
ABCF1	N/A	0.070	0.0425
GNB2L1	Lung cancer oncogene 7	0.070	0.052
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.070	0.052
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.070	0.0425
PTMA	N/A	0.070	0.052
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.052
MARK2	N/A	0.070	0.052
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.069	0.029
HIST1H1B	HIST1H1B, H1F5: Histone H1.5	0.069	0.111
FOSL2	FOSL2, FRA2: Fos-related antigen 2	0.069	0.136
GCN5L2	GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2	0.069	26.00
RANBP9	RANBP9, RANBPM: Ran-binding protein 9	0.069	0.029
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.069	0.136
IRF2	IRF2: Interferon regulatory factor 2	0.067	0.083
CAPN2	CAPN2, CANPL2: Calpain-2 catalytic subunit precursor	0.067	0.067
EXOC2	N/A	0.067	0.067
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.067	0.090
PLCB1	PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-	0.065	0.029
MCF2	MCF2, DBL: Proto-oncogene DBL	0.065	0.072
SPTAN1	N/A	0.065	0.081
LIMK1	LIMK1, LIMK: LIM domain kinase 1	0.064	0.029
EHBP1	EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1	0.064	0.041
PSD	TYL: TYL protein	0.064	0.033
PLD1	PLD1: Phospholipase D1	0.064	0.029
CENTA1	CENTA1: Centaurin-alpha 1	0.063	0.039
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.038
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.063	0.046
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.063	0.038
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.063	0.046
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.063	0.063
KIAA1012	KIAA1012: Protein TRS85 homolog	0.063	0.063
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.063	0.038
LIG1	LIG1: DNA ligase 1	0.063	0.029
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.063	0.063
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.063	0.063
NOL1	N/A	0.063	0.038
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.063	0.046
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.063	0.038
TIAL1	TIAL1: Nucleolysin TIAR	0.063	0.046
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.063	0.046
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.063	0.038
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.063	0.038
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.063	0.046
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.063	0.114
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.063	0.046
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.188
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.063	0.038
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.063	0.188
SATB1	SATB1: DNA-binding protein SATB1	0.063	0.225
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.063	0.038
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.063	0.046
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.063	0.038
CDKN1B	CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B	0.063	0.078
NUP153	N/A	0.063	0.038
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.063	0.046
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.063	90.40
PPP1R8	N/A	0.063	0.046
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.063	0.046
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.063	0.038
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.063	0.046
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.063	0.188
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.046
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.063	0.046
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.063	0.063
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.063	0.063
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.063	0.063
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.063	0.063
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.063	0.046
TNFRSF1A	TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre	0.063	0.029
TRIM16	TRIM16, EBBP: Tripartite motif-containing protein 16	0.062	0.055
GRLF1	N/A	0.062	0.026
TAF1	TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1	0.062	0.039
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.062	0.123
KCNH2	KCNH2, ERG, ERG1, HERG, HERG1: Potassium voltage-gated channel subfamily H membe	0.062	0.030
PTPRF	PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor	0.062	0.030
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.060	0.055
ZBTB33	KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso	0.060	0.062
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.060	0.026
SNTA1	SNTA1, SNT1: Alpha-1-syntrophin	0.058	0.026
CNKSR2	CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2	0.058	0.029
TAGLN	TAGLN, SM22, WS3-10: Transgelin	0.058	0.033
SCRIB	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4	0.057	0.075
PRKACB	PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit	0.056	0.028
SIPA1L1	SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein	0.056	0.086
MYST4	MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4	0.056	0.136
HIST1H1A	HIST1H1A, H1F1: Histone H1.1	0.056	0.097
MYF5	MYF5: Myogenic factor 5	0.056	0.049
ELK1	ELK1: ETS domain-containing protein Elk-1	0.056	0.111
ZNF551	N/A	0.054	0.136
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	0.054	0.111
TCF8	ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1	0.054	0.171
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.054	41.40
SP1	SP1, TSFP1: Transcription factor Sp1	0.054	33.10
ZNF579	ZNF579: Zinc finger protein 579	0.052	0.083
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.052	0.083
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.052	0.083
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.052	0.083
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.052	0.165
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.052	0.083
AFF1	N/A	0.052	0.0425
RGS14	N/A	0.052	0.052
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.052	0.032
IFI16	N/A	0.052	0.052
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.052	0.032
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.052	0.0425
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.052	0.052
TCOF1	N/A	0.052	0.0425
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.052	0.0425
CHUK	N/A	0.052	0.0425
SET	SET: Protein SET	0.052	0.032
NCOA3	N/A	0.052	0.052
TGIF2	TGIF2: Homeobox protein TGIF2	0.052	0.251
WDR1	N/A	0.052	0.052
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.052	0.0425
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.052	0.0425
RBM6	RBM6, DEF3: RNA-binding protein 6	0.052	0.0425
TRRAP	N/A	0.052	0.0425
PARVA	PARVA, MXRA2: Alpha-parvin	0.052	0.029
PRKD1	PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1	0.052	0.026
PLEC1	PLEC1: Plectin-1	0.051	0.051
STIM1	STIM1, GOK: Stromal interaction molecule 1 precursor	0.051	0.051
PLXND1	PLXND1, KIAA0620: Plexin-D1 precursor	0.0513	0.039
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.051	0.027
SMARCA1	SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1	0.050	0.044
PHC2	N/A	0.050	0.050
ETV1	ETV1, ER81: ETS translocation variant 1	0.049	0.109
KIAA0196	N/A	0.049	0.086
TRIM39	TRIM39, RNF23, TFP: Tripartite motif-containing protein 39	0.049	0.049
S100A16	S100A16, AAG13: Protein S100-A16	0.049	0.049
CAPN3	CAPN3, CANP3, CANPL3, NCL1: Calpain-3	0.049	0.049
PDZD2	CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P	0.049	0.049
RFX1	RFX1: MHC class II regulatory factor RFX1	0.049	0.097
FOXL2	FOXL2: Forkhead box protein L2	0.049	0.097
SH3BP3		0.048	0.127
EIF3S10	EIF3S10, KIAA0139: Eukaryotic translation initiation factor 3 subunit 10	0.047	0.029
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.047	0.075
CETN1	CETN1, CEN1, CETN: Centrin-1	0.047	0.075
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.047	0.025
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.047	0.075
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.047	0.075
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.047	0.075
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.047	0.075
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.047	0.075
SOX8	SOX8: Transcription factor SOX-8	0.047	0.025
COPA	COPA: Coatomer subunit alpha	0.046	0.046
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.046	0.038
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.046	0.046
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.046	0.038
EML4	EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4	0.046	0.038
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.046	0.046
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.046	0.046
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.046	0.038
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.046	0.029
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.046	0.038
CBX3	CBX3: Chromobox protein homolog 3	0.046	0.225
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.046	0.029
SRF	SRF: Serum response factor	0.046	0.038
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.046	0.038
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.046	0.038
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.046	0.046
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.046	0.038
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.046	0.372
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.046	0.029
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.046	0.038
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.046	0.038
KLHDC4	N/A	0.046	0.046
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.046	0.114
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.046	0.038
SSB	SSB: Lupus La protein	0.046	0.038
MDN1	MDN1, KIAA0301: Midasin	0.046	0.029
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.046	0.038
CUL4B	N/A	0.046	0.038
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.046	0.029
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.046	0.038
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.046	0.046
ARID3A	ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein	0.046	0.038
SAPS3	N/A	0.046	0.038
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.046	0.038
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.046	0.029
CUL5	CUL5, VACM1: Cullin-5	0.046	0.046
RUNX1	N/A	0.046	13.90
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.046	0.038
CIB1	CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1	0.046	0.057
RAB32	RAB32: Ras-related protein Rab-32	0.046	0.029
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.0453	0.100
CEACAM6	CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso	0.045	0.051
CFLAR	CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec	0.0446	0.036
GABPA	GABPA, E4TF1A: GA-binding protein alpha chain	0.044	0.028
HES1	HES1, HL, HRY: Transcription factor HES-1	0.044	0.044
RASGRP3	RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3	0.044	0.044
GOPC	GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein	0.044	0.044
RASGRP2	RASGRP2: RAS guanyl-releasing protein 2	0.044	0.044
PARD6A	PARD6A, PAR6A: Partitioning defective 6 homolog alpha	0.044	0.044
LRRC7	LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7	0.044	0.044
SUPT5H	SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5	0.044	0.054
KIAA1967	KIAA1967, DBC1: Protein KIAA1967	0.043	0.056
KCTD12	KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12	0.043	0.038
NR4A2	NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2	0.043	65.60
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.043	26.80
VDR	VDR, NR1I1: Vitamin D3 receptor	0.043	0.136
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.043	0.111
EEA1	EEA1, ZFYVE2: Early endosome antigen 1	0.043	0.056
GTF3C1	N/A	0.0425	0.0425
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.0425	0.0425
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.0425	0.032
ID2	ID2: DNA-binding protein inhibitor ID-2	0.0425	0.155
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.0425	0.0425
SMARCC2	N/A	0.0425	0.052
MECP2	MECP2: Methyl-CpG-binding protein 2	0.0425	0.0425
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.0425	0.0425
MYB	MYB: Myb proto-oncogene protein	0.0425	0.123
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.0425	0.251
API5	N/A	0.0425	0.032
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.0425	0.032
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.0425	0.251
UBAP2	N/A	0.0425	0.0425
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.0425	0.026
EMD	EMD, EDMD, STA: Emerin	0.0425	0.032
NUP214	N/A	0.0425	0.0425
HPCAL1	HPCAL1, BDR1: Hippocalcin-like protein 1	0.041	0.067
EPS15	EPS15, AF1P: Epidermal growth factor receptor substrate 15	0.041	0.067
RYR2	RYR2: Ryanodine receptor 2	0.041	0.025
KIAA0157	KIAA0157: Uncharacterized protein KIAA0157	0.0407	0.0782
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.041	13.60
IRF5	IRF5: Interferon regulatory factor 5	0.041	0.041
RAP1B	RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor	0.040	0.032
ARHGDIB	ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2	0.040	0.032
UBE4A	N/A	0.040	0.032
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.040	0.032
HNRPK	N/A	0.040	0.032
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.039	0.123
ZFP36	ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline	0.038	0.038
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.038	0.029
AHR	AHR: Aryl hydrocarbon receptor precursor	0.038	0.086
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.038	0.038
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.038	0.038
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.038	0.029
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.038	0.038
MTA1	MTA1: Metastasis-associated protein MTA1	0.038	0.114
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.038	0.063
SEC31L1	N/A	0.038	0.038
COPE	COPE: Coatomer subunit epsilon	0.038	0.038
SMAD4	SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4	0.038	0.114
UNG	N/A	0.038	0.029
GSK3B	N/A	0.038	0.046
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.038	0.029
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.038	0.029
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.038	0.029
RERE	RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei	0.038	0.275
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.038	41.40
FZR1	N/A	0.038	0.038
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.038	0.029
POLA2	POLA2: DNA polymerase subunit alpha B	0.038	0.029
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.038	0.029
DYNC1LI1	DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1	0.038	0.046
RBM7		0.038	0.038
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.038	0.063
WDR44	WDR44: WD repeat-containing protein 44	0.038	0.038
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.038	0.029
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.036	0.036
DNM2	N/A	0.036	0.027
EHD4	EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4	0.036	0.044
AP1GBP1	AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1	0.036	0.044
KCNIP3	KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin	0.036	0.044
SNAI1	SNAI1, SNAH: Zinc finger protein SNAI1	0.035	0.056
EGR1	EGR1, ZNF225: Early growth response protein 1	0.035	0.056
ZHX3	ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3	0.034	0.123
ESR1	ESR1, ESR, NR3A1: Estrogen receptor	0.034	0.109
PGR	PGR, NR3C3: Progesterone receptor	0.034	0.109
MYL4	MYL4, MLC1, PRO1957: Myosin light polypeptide 4	0.033	0.029
CHP	CHP: Calcium-binding protein p22	0.033	0.051
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.032	0.251
CENPA	CENPA: Histone H3-like centromeric protein A	0.032	0.062
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.032	0.026
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.032	0.251
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.032	0.032
SAT	SAT1, SAT: Diamine acetyltransferase 1	0.032	0.0425
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.032	0.032
SREBF2	N/A	0.032	0.032
RAP1A	RAP1A, KREV1: Ras-related protein Rap-1A precursor	0.032	0.040
PPP2R5A	PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha	0.032	0.032
SEC24B	SEC24B: Protein transport protein Sec24B	0.032	0.032
SALL1	SALL1, SAL1: Sal-like protein 1	0.031	0.049
KLF5	KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5	0.031	0.044
PPARG	CREB3L2-PPARgamma	0.0308	0.111
ZBTB16	ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16	0.0308	0.056
ATXN7	ATXN7, SCA7: Ataxin-7	0.030	0.0407
S100A3	S100A3, S100E: Protein S100-A3	0.029	0.029
S100B	S100B: Protein S100-B	0.029	0.032
S100A7	S100A7, PSOR1: Protein S100-A7	0.029	0.032
SYMPK	SYMPK, SPK: Symplekin	0.029	0.029
DNAJC7	DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7	0.029	0.029
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.029	0.029
H2AFX	H2AFX, H2AX: Histone H2A.x	0.029	0.069
CORO1C	CORO1C, CRNN4: Coronin-1C	0.029	0.029
SMAD3	SMAD3, MADH3: Mothers against decapentaplegic homolog 3	0.029	41.40
HIST3H3	HIST3H3, H3FT: Histone H3.1t	0.029	0.086
MYBL2	MYBL2, BMYB: Myb-related protein B	0.029	0.111
TSC1	TSC1, KIAA0243, TSC: Hamartin	0.029	0.029
MEF2D	MEF2D: Myocyte-specific enhancer factor 2D	0.029	0.029
DUSP22	DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22	0.029	0.046
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.029	0.029
COPB2	COPB2: Coatomer subunit beta'	0.029	0.029
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.029
CLASP1	CLASP1, KIAA0622, MAST1: CLIP-associating protein 1	0.029	0.046
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.029	0.114
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.029	0.038
POLB	POLB: DNA polymerase beta	0.029	0.038
KIAA0690	N/A	0.029	0.038
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
CABLES1	N/A	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.083
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
WDR54	N/A	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
CORO6	N/A	0.028	0.028
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.028	0.083
PHLDB2	N/A	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.165
IRF7	N/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
DUSP15	N/A	0.028	0.028
UHRF1		0.028	0.083
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.083
BID	BID: BH3-interacting domain death agonist	0.028	0.028
ZNF265	N/A	0.028	0.028
C13orf8	N/A	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.165
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
SNRPB	N/A	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
NES	N/A	0.028	0.028
RAB4A	N/A	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.083
C20orf18	N/A	0.028	0.083
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
KIF1B	N/A	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
NR1D1	NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1	0.028	53.10
NR4A1	CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor	0.028	0.088
BNC1	BNC1, BNC: Zinc finger protein basonuclin-1	0.028	0.044
CUL2	CUL2: Cullin-2	0.027	0.076
CALM2	CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca	0.027	0.090
VSNL1	VSNL1, VISL1: Visinin-like protein 1	0.027	0.029
SYNE2	SYNE2, KIAA1011, NUA: Nesprin-2	0.027	0.027
DST	DST, BPAG1, DMH, DT, KIAA0728: Bullous pemphigoid antigen 1, isoform 7 (Fragment	0.027	0.027
OSBPL9	N/A	0.027	0.027
IRF7	IRF7: Interferon regulatory factor 7	0.027	0.027
C20orf116	C20orf116: Uncharacterized protein C20orf116 precursor	0.027	0.027
NOS1	NOS1: Nitric-oxide synthase, brain	0.026	0.029
RIMS1	RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos	0.026	0.029
PARD3	N/A	0.026	0.026
COIL	COIL, CLN80: Coilin	0.026	0.032
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.026	0.032
XRCC4	N/A	0.026	0.026
PER2	PER2, KIAA0347: Period circadian protein homolog 2	0.026	0.096
MEF2A	N/A	0.026	0.052
SMAD7	SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7	0.026	0.096
ADAR	ADAR, ADAR1, DSRAD, G1P1, IFI4: Double-stranded RNA-specific adenosine deaminase	0.0255	0.083
ELF4	ELF4, ELFR, MEF: ETS-related transcription factor Elf-4	0.0255	0.067
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.075
BCOR	N/A	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.075
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.148
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.075
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	35.90
NIPBL	N/A	0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
GRK6	N/A	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.075
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
SON		0.025	0.025
MAPK8IP3	N/A	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
MAX	MAX: Protein max	0.025	0.075
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
KCTD1		0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.075
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.075
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.025	0.075
PRKCB1	N/A	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.075
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
DIDO1	N/A	0.025	0.075
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
CAMK2A	N/A	0.025	0.025
RNF20		0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.075
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
CAMKK1	N/A	0.025	0.025
HTATIP	N/A	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.148
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.148
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.148
NUP98	N/A	0.025	0.025
ATXN2L	N/A	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.075
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.025	0.075
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.025
FLJ23436	N/A	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
SEC13L1	N/A	0.025	0.025
C20orf77	N/A	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
LMNA	LMNA, LMN1: Lamin-A/C	0.025	0.025
TCEA1	N/A	0.025	0.025

0.347

Total Score

1.55E4