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Evidence of Interaction Between CGA and CGB

The interaction score between CGA and CGB is 486.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between CGA and CGB = 0.61

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 7.78E-3
Orthology N/A N/A
Domains Domains present in CGA and CGB:
Domains in CGADomains in CGB
IPR002400 Growth factor, cystine knot
IPR000476 Glycoprotein hormone alpha chain
IPR002400 Growth factor, cystine knot
IPR006208 Cystine knot domain
IPR001545 Gonadotropin, beta chain

The Chi square scores for co-occurrence of domains that are present in CGA and CGB are listed below.

Domain 1Domain 2Chi Square
IPR002400 Growth factor, cystine knot IPR002400 Growth factor, cystine knot 181.441
IPR000476 Glycoprotein hormone alpha chain IPR002400 Growth factor, cystine knot 159.352
IPR002400 Growth factor, cystine knot IPR006208 Cystine knot domain 140.868
IPR002400 Growth factor, cystine knot IPR001545 Gonadotropin, beta chain 121.963

The background colour of the table refers to:

  • Blue Domain is only present in CGA
  • Yellow Domain is only present in CGB
  • Green Domain is present in both CGA and CGB

 1.30
Post-translational Modifications

Protein: CGA

PTMResidueReference
Deglycosylation 76 PubMed, HPRD
Deglycosylation 102 PubMed, HPRD
Glycosylation 76 PubMed, HPRD
Glycosylation 102 PubMed, HPRD
N-linked 76 PubMed, HPRD
N-linked 102 PubMed, HPRD
O-linked 63 HPRD

Protein: CGB

PTMResidueReference
Disulfide Bridge 77 PubMed, HPRD
Disulfide Bridge 92 PubMed, HPRD
Disulfide Bridge 108 PubMed, HPRD
Disulfide Bridge 110 PubMed, HPRD
Disulfide Bridge 120 PubMed, HPRD
Disulfide Bridge 130 PubMed, HPRD
Glycosylation 33 PubMed, HPRD
Glycosylation 50 PubMed, HPRD
N-linked 33 PubMed, HPRD
N-linked 50 PubMed, HPRD
O-linked 141 PubMed, HPRD
O-linked 147 PubMed, HPRD
O-linked 152 PubMed, HPRD
O-linked 158 PubMed, HPRD
Phosphorylation 86 PubMed, HPRD
Phosphorylation 116 PubMed, HPRD
Phosphorylation 117 PubMed, HPRD
Localisation

Protein: CGA

LocalisationReference
ER HPRD
Golgi HPRD
Secreted HPRD

Protein: CGB

LocalisationReference
Secreted HPRD
Transitive Score

The common interactors between CGA and CGB that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CGA andCGB. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CGA has 601 interactors and CGB has 736 interactors of which there are 580 common interactors.

Common InteractorName of Common InteractorScore for CGA-Interactor (?)Score for CGB-Interactor (?)
LHB LHB: Lutropin subunit beta precursor 14.30 0.123
TSHB TSHB: Thyrotropin subunit beta precursor 6.73 0.123
FSHB FSHB: Follitropin subunit beta precursor 6.73 0.123
CTGF CTGF, CCN2, HCS24: Connective tissue growth factor precursor 0.975 0.123
CSH2 GH1: Somatotropin precursor 0.923 0.052
MUC2 MUC2, SMUC: Mucin-2 precursor 0.859 0.123
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.416 5.45
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.416 1.81
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.307 0.852
COL15A1 COL15A1: Collagen alpha-1(XV) chain precursor [Contains: Endostatin 0.307 0.852
WISP3 LIBC, WISP3, RP1-142L7.3-004, hCG_34804: Lost in inflammatory breast cancer tumo 0.265 0.027
WISP1 WISP1, CCN4: WNT1-inducible-signaling pathway protein 1 precursor 0.265 0.027
WISP3 WISP3, CCN6, UNQ462/PRO790/PRO956: WNT1-inducible-signaling pathway protein 3 pr 0.265 0.027
F7 F7: Coagulation factor VII precursor 0.209 0.174
BGN BGN: Biglycan precursor 0.191 0.307
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.191 0.191
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.166 0.166
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.165
OPTC OPTC, OPT: Opticin precursor 0.165 0.165
DCN DCN: Decorin precursor 0.165 0.165
C4A C4A: Complement C4-A precursor 0.165 0.165
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.165 0.165
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.165 0.165
SPOCK1 SPOCK1, SPOCK, TIC1, TICN1: Testican-1 precursor 0.165 0.165
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.156 0.156
BGLAP BGLAP: Osteocalcin precursor 0.152 0.152
C1QC C1QC, C1QG: Complement C1q subcomponent subunit C precursor 0.152 0.152
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.152 0.152
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.152 0.191
INHA INHA: Inhibin alpha chain precursor 0.152 0.191
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.152 0.152
A2M A2M, FWP007: Alpha-2-macroglobulin precursor 0.152 0.152
DSPG3 EPYC, DSPG3, PGLB: Epiphycan precursor 0.152 0.191
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.152 0.191
SLIT2 SLIT2, SLIL3: Slit homolog 2 protein precursor 0.152 0.109
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.152 0.191
LUM LUM, LDC: Lumican precursor 0.152 0.251
VWF VWF, F8VWF: von Willebrand factor precursor 0.152 0.191
C1QA C1QA: Complement C1q subcomponent subunit A precursor 0.140 0.176
F9 F9: Coagulation factor IX precursor 0.137 0.115
PROC PROC: Vitamin K-dependent protein C precursor 0.137 0.115
F10 F10: Coagulation factor X precursor 0.137 0.115
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.130 0.115
COL5A1 N/A 0.130 0.201
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.128 0.214
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.127 0.307
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.126 0.166
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.126 0.166
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.126 0.202
INSR INSR: Insulin receptor precursor 0.126 0.202
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.123 0.123
C7 C7: Complement component C7 precursor 0.123 0.161
ALK ALK: ALK tyrosine kinase receptor precursor 0.123 0.123
LAMA2 LAMA2: Uncharacterized protein LAMA2 0.123 0.123
CFI CFI, IF: Complement factor I precursor 0.123 0.109
PZP PZP: Pregnancy zone protein precursor 0.123 0.123
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.123 0.109
SPARC SPARC, ON: SPARC precursor 0.123 0.152
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.123 0.123
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.123 0.123
COL1A1 COL1A1: Collagen alpha-1(I) chain precursor 0.123 0.161
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.123 0.152
THBS1 THBS1, TSP, TSP1: Thrombospondin-1 precursor 0.123 0.130
COL3A1 COL3A1: Collagen alpha-1(III) chain precursor 0.123 0.161
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.123 0.152
SPON1 SPON1, KIAA0762, VSGP: Spondin-1 precursor 0.123 0.130
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.114 0.114
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.109 0.109
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.109 0.109
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.109 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.109 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.109 0.109
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.109 0.109
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.109 0.109
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.109 0.109
JAG2 JAG2: Jagged-2 precursor 0.109 0.109
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.109 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.109 0.109
SPINK1 SPINK1, PSTI: Pancreatic secretory trypsin inhibitor precursor 0.109 0.109
LGALS3 LGALS3, MAC2: Galectin-3 0.109 0.123
SHBG SHBG: Sex hormone-binding globulin precursor 0.109 0.109
C6 C6: Complement component C6 precursor 0.109 0.115
CFP CFP, PFC: Properdin precursor 0.109 0.115
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.109 0.109
APCS APCS, PTX2: Serum amyloid P-component precursor 0.109 0.109
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.109 0.123
IGFALS IGFALS, ALS: Insulin-like growth factor-binding protein complex acid labile chai 0.109 0.109
ASPN ASPN: ASPN protein 0.109 0.109
SERPIND1 SERPIND1, HCF2: Heparin cofactor 2 precursor 0.109 0.109
C3 0.109 0.109
C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 0.109 0.130
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.109 0.109
C8A C8A: Complement component C8 alpha chain precursor 0.109 0.115
NDP NDP: Norrin precursor 0.109 0.109
KERA KERA: Keratocan precursor 0.109 0.098
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.109 0.109
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.109 0.109
C8B C8B: Complement component C8 beta chain precursor 0.109 0.115
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.109 0.109
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.105 0.173
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.100 0.100
MET MET: Hepatocyte growth factor receptor precursor 0.100 0.100
TPBG TPBG, 5T4: Trophoblast glycoprotein precursor 0.100 0.100
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.100 0.100
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.100 0.126
GP1BA N/A 0.100 0.100
ADIPOQ ADIPOQ, ACDC, ACRP30, APM1, GBP28: Adiponectin precursor 0.100 0.100
F2 F2: Prothrombin precursor 0.100 0.100
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.100 0.100
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.083 0.083
NULL A1BG: Alpha-1B-glycoprotein precursor 0.083 0.083
CNTN1 CNTN1: Contactin-1 precursor 0.083 0.083
CNTN4 CNTN4: Contactin-4 precursor 0.083 0.083
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.083 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.083 0.083
BMP1 N/A 0.083 0.165
PLAT PLAT: Tissue-type plasminogen activator precursor 0.083 0.083
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.083 0.083
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.081 0.100
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.081 0.100
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.081 0.081
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.081 0.081
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.081 0.081
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.081 0.100
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.081 0.100
CANX CANX: Calnexin precursor 0.0794 0.0794
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.0794 0.105
THBD THBD, THRM: Thrombomodulin precursor 0.077 0.251
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.077 0.191
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.075 0.340
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.075 0.153
NEO1 NEO1, NGN: Neogenin precursor 0.072 0.081
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.072 0.072
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.072 0.072
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.072 0.081
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.072 0.081
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.072 0.072
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.072 0.072
KIT KIT: Mast/stem cell growth factor receptor precursor 0.072 0.072
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.072 0.072
TLR4 TLR4: Toll-like receptor 4 precursor 0.072 0.072
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.072 0.072
SLITRK5 SLITRK5, KIAA0918, LRRC11: SLIT and NTRK-like protein 5 precursor 0.072 0.072
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.072 0.072
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.072 0.065
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.072 0.072
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.072 0.065
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.072 0.072
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.072 0.081
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.072 0.072
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.072 0.072
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.072 0.072
DCC DCC: Netrin receptor DCC precursor 0.072 0.072
TSHR N/A 0.072 0.072
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.072 0.065
PAPPA PAPPA, RP11-45A16.1-001: Pregnancy-associated plasma protein A, pappalysin 1 (Fr 0.070 0.923
MMP11 MMP11, STMY3: Stromelysin-3 precursor 0.070 0.923
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.0688 0.0688
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.0688 0.0688
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.0688 0.0688
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.0688 0.0688
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.0688 0.0688
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.0688 0.0688
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.0688 0.0688
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.0688 0.0688
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.0688 0.0688
MAPKAPK5 N/A 0.0688 0.0688
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.0688 0.0688
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.0688 0.0688
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.0688 0.0688
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.0688 0.0688
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.0688 0.0688
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.0688 0.0688
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.0688 0.0688
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.0688 0.0688
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.0688 0.0688
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.0688 0.0688
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.0688
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.0688 0.0688
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.0688 0.0688
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.0688 0.0688
MAPK15 N/A 0.0688 0.0688
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.0688 0.0688
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.0688 0.0688
CDC2 CDC2: Cell division control protein 2 homolog 0.0688 0.0688
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.0688 0.0688
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.0688 0.0688
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.0688 0.0688
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.0688 0.0688
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.0688 0.0688
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.0688 0.0688
CRIM1 CRIM1, S52, UNQ1886/PRO4330: Cysteine-rich motor neuron 1 protein precursor 0.067 0.293
GP5 GP5: Platelet glycoprotein V precursor 0.065 0.065
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.063 0.105
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.063 0.063
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.063 0.0794
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.063 0.051
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.063 0.045
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.063 0.063
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.063 0.0794
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.063 0.041
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.063 0.051
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.062 0.123
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.062 0.123
C1R C1R: Complement C1r subcomponent precursor 0.062 0.109
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.057 0.075
SPINK2 SPINK2: Serine protease inhibitor Kazal-type 2 precursor 0.056 0.165
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.056 0.165
CSPG2 N/A 0.055 0.109
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.055 0.055
C1S C1S: Complement C1s subcomponent precursor 0.055 0.109
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.055 0.055
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.055 0.055
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.055 0.062
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.055 0.062
UMOD UMOD: Uromodulin precursor 0.055 0.109
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.055 0.137
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.055 0.055
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.055 0.055
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.055 0.062
TNC TNC, HXB: Tenascin precursor 0.055 0.109
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.055 0.109
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.055 0.123
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.055 0.055
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.055 0.055
F12 F12: Coagulation factor XII precursor 0.055 0.109
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.055 0.055
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.055 0.055
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.055 0.055
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.055 0.055
NOTCH4 N/A 0.055 0.123
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.055 0.109
PRG2 PRG2, MBP: Bone marrow proteoglycan precursor 0.052 0.087
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.051
SPOCK3 SPOCK3, TICN3, UNQ409/PRO771: Testican-3 precursor 0.051 0.051
C5 C5: Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 a 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
FMOD FMOD, FM: Fibromodulin precursor 0.051 0.051
SPARCL1 SPARCL1: SPARC-like protein 1 precursor 0.051 0.051
FLT4 VEGFR3 long form 0.051 0.051
COL2A1 N/A 0.051 0.051
C4B C4B: Complement C4-B precursor 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.051
CPN2 CPN2, ACBP: Carboxypeptidase N subunit 2 precursor 0.051 0.051
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.051 0.045
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.051 0.051
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.051 0.045
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.051 0.051
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.051 0.051
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.051 0.041
CDK7 CDK7, MO15: Cell division protein kinase 7 0.051 0.051
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.051 0.041
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.051 0.051
CDK4 CDK4: Cell division protein kinase 4 0.051 0.045
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.051 0.045
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.051 0.045
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.051 0.063
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.051 0.045
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.051 0.063
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.051 0.045
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.051 0.063
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.051 0.051
CDK2 CDK2: Cell division protein kinase 2 0.051 0.063
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.051 0.051
WEE1 WEE1: Wee1-like protein kinase 0.051 0.063
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.051 0.051
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.051 0.051
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.051 0.051
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.051 0.063
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.051 0.051
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.051 0.063
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.051 0.063
HTRA1 HTRA1, HTRA, PRSS11: Serine protease HTRA1 precursor 0.050 0.067
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.049 0.049
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.049 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.049 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.049
KIR3DL1 N/A 0.049 0.049
DLK1 DLK1, DLK: Delta-like protein precursor 0.049 0.049
BSG N/A 0.049 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.049 0.109
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.049 0.109
ATRN N/A 0.049 0.049
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.049 0.109
TMPRSS9 N/A 0.049 0.049
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.049 0.049
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.049
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.049 0.109
C3AR1 C3AR1, AZ3B, C3R1, HNFAG09: C3a anaphylatoxin chemotactic receptor 0.049 0.109
TBXA2R TBXA2R: Thromboxane A2 receptor 0.049 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.049 0.049
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.049 0.049
DRD2 DRD2: D(2) dopamine receptor 0.049 0.109
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.049 0.049
ITGB4 N/A 0.0453 0.057
CSPG4 CSPG4, MCSP: Chondroitin sulfate proteoglycan 4 precursor 0.0453 0.0453
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.0453 0.075
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.045 0.041
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.045 0.045
STK16 N/A 0.045 0.045
RPS6KB1 N/A 0.045 0.045
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.045 0.045
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.045 0.045
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.045 0.045
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.045 0.045
PRKAA1 N/A 0.045 0.045
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.045 0.045
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.045 0.045
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.045 0.045
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.045 0.045
SYK SYK: Tyrosine-protein kinase SYK 0.045 0.045
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.045 0.045
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.045 0.045
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.045 0.045
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.045 0.045
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.045 0.045
MYO3A MYO3A: Myosin IIIA 0.045 0.045
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.045 0.045
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.045 0.045
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.045 0.045
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.045 0.045
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.045 0.045
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.045 0.051
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.045 0.045
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.045 0.045
CIITA CIITA, MHC2TA: MHC class II transactivator 0.045 0.045
DAPK2 DAPK2: Death-associated protein kinase 2 0.045 0.045
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.045 0.045
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.045 0.051
STK10 STK10: Uncharacterized protein STK10 0.045 0.045
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.045 0.045
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.045 0.045
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.045 0.045
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.045 0.045
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.045 0.045
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.045 0.045
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.045 0.051
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.045 0.045
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.045 0.045
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.045 0.045
CDK5 CDK5: Cell division protein kinase 5 0.045 0.045
JAK1 0.045 0.045
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.045 0.045
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.045 0.045
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.045 0.045
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.045 0.051
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.045 0.051
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.045 0.045
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.045 0.045
LMAN2 LMAN2, C5orf8: Vesicular integral-membrane protein VIP36 precursor 0.045 0.051
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.045 0.041
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.045 0.045
CSK CSK: Tyrosine-protein kinase CSK 0.045 0.045
BMX N/A 0.045 0.045
TTN N/A 0.045 0.045
LYN LYN: Tyrosine-protein kinase Lyn 0.045 0.051
HCK N/A 0.045 0.045
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.045 0.045
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.045 0.045
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.045 0.045
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.045 0.045
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.045 0.045
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.045 0.051
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.045 0.051
FLII FLII, FLIL: Protein flightless-1 homolog 0.045 0.045
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.045 0.051
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.045 0.045
FNTB FNTB: Protein farnesyltransferase subunit beta 0.0416 0.123
ROCK1 ROCK1: Rho-associated protein kinase 1 0.041 0.041
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.041 0.045
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.041 0.045
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.041 0.041
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.0407 0.126
FSTL3 FSTL3, FLRG, UNQ674/PRO1308: Follistatin-related protein 3 precursor 0.041 0.067
INHBA INHBA: Inhibin beta A chain precursor 0.041 0.083
AVPR1B AVPR1B, AVPR3, VPR3: Vasopressin V1b receptor 0.039 0.045
SLCO4A1 SLCO4A1, OATP1, OATPE, SLC21A12: Solute carrier organic anion transporter family 0.038 0.047
EDG1 EDG1: Sphingosine 1-phosphate receptor Edg-1 0.037 0.100
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.037 0.057
HTR6 HTR6: 5-hydroxytryptamine receptor 6 0.037 0.072
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.037 0.037
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.037 0.037
CHRM2 CHRM2: Muscarinic acetylcholine receptor M2 0.037 0.081
PVR PVR, PVS: Poliovirus receptor precursor 0.037 0.037
P2RY4 P2RY4, NRU: P2Y purinoceptor 4 0.037 0.081
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.037 0.029
AREG AREG, SDGF: Amphiregulin precursor 0.037 0.037
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.037 0.0453
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.037 0.0453
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.037 0.0453
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.037 0.081
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.037 0.037
MEP1A MEP1A: Meprin A subunit alpha precursor 0.037 0.072
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.037 0.037
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.037 0.0453
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.037 0.100
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.037 0.029
TACR2 TACR2, NK2R, NKNAR, TAC2R: Substance-K receptor 0.037 0.072
MT2A MT2A, CES1, MT2: Metallothionein-2 0.037 0.037
LGALS1 LGALS1: Galectin-1 0.037 0.109
COL16A1 COL16A1: Collagen alpha-1(XVI) chain precursor 0.037 0.109
MT1F MT1F, PRO0376: Metallothionein-1F 0.037 0.037
LOC645745 MT1H: Metallothionein-1H 0.037 0.037
MT1X MT1X: Metallothionein-1X 0.037 0.037
ADAM12 N/A 0.036 0.472
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.0338 0.0338
SPOCK2 SPOCK2, KIAA0275, UNQ269/PRO306, TICN2: Testican-2 precursor 0.0338 0.0338
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.0338 0.030
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.034 0.0688
PTGS1 PTGS1, COX1: Prostaglandin G/H synthase 1 precursor 0.034 0.0688
EEF2K EEF2K: Elongation factor 2 kinase 0.034 0.034
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.032 0.037
FPRL1 FPRL1, FPR2, FPRH1, LXA4R: FMLP-related receptor I 0.032 0.072
MC4R MC4R: Melanocortin receptor 4 0.032 0.072
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.032 0.032
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.032 0.072
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.032 0.037
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.032 0.032
FPR1 FPR1: fMet-Leu-Phe receptor 0.032 0.072
SSTR3 SSTR3: Somatostatin receptor type 3 0.032 0.072
SELE SELE, ELAM1: E-selectin precursor 0.032 0.072
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.032 0.032
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.032 0.037
GP1BB GP1BB: Platelet glycoprotein Ib beta chain precursor 0.032 0.072
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.032 0.037
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.032 0.072
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.032 0.037
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.032 0.032
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.032 0.032
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.032 0.032
F2R F2R, CF2R, PAR1, TR: Proteinase-activated receptor 1 precursor 0.032 0.081
HTR2C HTR2C, HTR1C: 5-hydroxytryptamine receptor 2C 0.032 0.072
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.032 0.032
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.032 0.032
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.032 0.037
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.032 0.032
DRD1 DRD1: D(1A) dopamine receptor 0.032 0.072
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.032 0.032
CD7 CD7: T-cell antigen CD7 precursor 0.032 0.032
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.032 0.032
LDLR LDLR: Low-density lipoprotein receptor precursor 0.032 0.081
C5AR1 C5AR1, C5AR, C5R1: C5a anaphylatoxin chemotactic receptor 0.032 0.072
SORL1 SORL1: Sortilin-related receptor precursor 0.032 0.032
ITGB7 ITGB7: Integrin beta-7 precursor 0.032 0.032
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.032 0.072
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.032 0.072
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.032 0.072
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.032 0.072
EGF EGF: Pro-epidermal growth factor precursor 0.032 0.072
TRHR TRHR: Thyrotropin-releasing hormone receptor 0.032 0.072
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.032 0.072
F2RL1 F2RL1, GPR11, PAR2: Proteinase-activated receptor 2 precursor 0.032 0.072
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.032 0.032
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.032 0.072
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.032 0.032
IL8RB IL8RB, CXCR2: High affinity interleukin-8 receptor B 0.032 0.072
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.032 0.072
CCR5 CCR5: CCR5 receptor (Fragment) 0.032 0.072
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.032 0.032
RHO RHO, OPN2: Rhodopsin 0.032 0.072
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.032 0.032
SPINT2 SPINT2, HAI2, KOP: Kunitz-type protease inhibitor 2 precursor 0.032 0.026
LGALS3BP LGALS3BP, M2BP: Galectin-3-binding protein precursor 0.032 0.026
IGF2 IGF2, PP1446: Insulin-like growth factor II precursor 0.032 0.052
COL4A1 N/A 0.032 0.070
GAA GAA: Uncharacterized protein GAA 0.032 0.0425
LGR5 LGR5, GPR49, GPR67: Leucine-rich repeat-containing G-protein coupled receptor 5 0.032 0.053
AVPR2 AVPR2, ADHR, DIR, DIR3, V2R: Vasopressin V2 receptor 0.031 0.051
F2RL3 F2RL3, PAR4: Proteinase-activated receptor 4 precursor 0.029 0.065
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.029 0.065
GPR23 LPA4, GPR23, P2RY9: Lysophosphatidic acid receptor 4 0.029 0.072
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.029 0.032
F2RL2 F2RL2, PAR3: Proteinase-activated receptor 3 precursor 0.029 0.065
GPA33 GPA33: Cell surface A33 antigen precursor 0.029 0.029
MEP1B MEP1B: Meprin A subunit beta precursor 0.029 0.072
GP9 GP9: Platelet glycoprotein IX precursor 0.029 0.072
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.029 0.072
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.029 0.081
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.029 0.072
COL1A2 COL1A2: Collagen alpha-2(I) chain precursor 0.029 0.029
C1QB N/A 0.029 0.029
KNG1 KNG1, BDK, KNG: Kininogen-1 precursor 0.029 0.029
ITIH2 ITIH2, IGHEP2: Inter-alpha-trypsin inhibitor heavy chain H2 precursor 0.029 0.029
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.029 0.029
VNN1 VNN1: Pantetheinase precursor 0.028 0.028
ECM1 ECM1: Extracellular matrix protein 1 precursor 0.028 0.028
IFNG IFNG: Interferon gamma precursor 0.028 0.028
CCL26 CCL26, SCYA26, UNQ216/PRO242: Small-inducible cytokine A26 precursor 0.028 0.028
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.028 0.028
LECT1 LECT1, CHMI: Chondromodulin-1 precursor 0.028 0.028
UNC5D N/A 0.028 0.028
ITM2C ITM2C, BRI3, hucep-14, NPD018, PSEC0047: Integral membrane protein 2C 0.028 0.028
IL4 IL4: Interleukin-4 precursor 0.028 0.028
GUCA2A GUCA2A, GUCA2: Guanylin precursor 0.028 0.028
TFPI TFPI, LACI, TFPI1: Tissue factor pathway inhibitor precursor 0.028 0.028
SCRIB N/A 0.028 0.028
CCL14 N/A 0.028 0.028
KITLG KITLG, MGF, SCF: Kit ligand precursor 0.028 0.028
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.028 0.028
F11 F11: Coagulation factor XI precursor 0.028 0.028
CSF3 CSF3, GCSF: Granulocyte colony-stimulating factor precursor 0.028 0.028
CST4 CST4: Cystatin-S precursor 0.028 0.028
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.028 0.028
TUBGCP6 TUBGCP6, GCP6, KIAA1669: Gamma-tubulin complex component 6 0.028 0.028
C1QTNF4 C1QTNF4, CTRP4: Complement C1q tumor necrosis factor-related protein 4 precursor 0.028 0.028
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.028 0.028
GHRL GHRL, MTLRP, UNQ524/PRO1066: Appetite-regulating hormone precursor 0.028 0.028
THPO THPO, MGDF: Thrombopoietin precursor 0.028 0.028
COL18A1 N/A 0.028 0.028
KLK3 KLK3, APS: Prostate-specific antigen precursor 0.028 0.028
NOG NOG: Noggin precursor 0.028 0.028
CA11 CA11, CARP2, UNQ211/PRO237: Carbonic anhydrase-related protein 11 precursor 0.028 0.028
LOC643930 CCL3L1, D17S1718, G0S19-2, SCYA3L1: Small-inducible cytokine A3-like 1 precursor 0.028 0.028
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.028 0.028
PCGF6 N/A 0.028 0.028
MMRN2 MMRN2, EMILIN3: Multimerin-2 precursor 0.028 0.028
PLAU Plasminogen activator, urokinase 0.028 0.028
PTHLH N/A 0.028 0.028
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.028 0.028
CD46 N/A 0.028 0.028
CCL15 CCL15, MIP5, NCC3, SCYA15: Small-inducible cytokine A15 precursor 0.028 0.028
LNX1 N/A 0.028 0.028
CPB2 CPB2: Carboxypeptidase B2 precursor 0.028 0.028
GRN GRN: Granulins precursor 0.028 0.028
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.028 0.028
ACCN3 ACCN3, ASIC3, SLNAC1, TNAC1: Amiloride-sensitive cation channel 3 0.028 0.028
LOC641705 AMY2A: Pancreatic alpha-amylase precursor 0.028 0.028
PLTP PLTP: Phospholipid transfer protein precursor 0.028 0.028
CGN N/A 0.028 0.028
CFHR1 CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2: Complement factor H-relate 0.028 0.028
CSF1 CSF1: Macrophage colony-stimulating factor 1 precursor 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.028
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.028 0.028
IRF2BP2 IRF2BP2, RP4-781K5.1-002: Interferon regulatory factor 2-binding protein 2. 0.028 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.028 0.028
PCSK6 N/A 0.028 0.028
FN1 N/A 0.028 0.152
GRP Gastrin-releasing peptide 0.028 0.028
COL5A2 COL5A2: Collagen alpha-2(V) chain precursor 0.027 0.027
ADAMTS17 ADAMTS17: ADAMTS-17 precursor 0.027 0.027
GDNF GDNF: Glial cell line-derived neurotrophic factor precursor 0.027 0.027
SPINK7 SPINK7, ECG2, UNQ745/PRO1474: Serine protease inhibitor Kazal-type 7 precursor 0.027 0.027
ADAMTS10 ADAMTS10: ADAMTS-10 precursor 0.027 0.027
CILP2 CILP2: Cartilage intermediate layer protein 2 precursor 0.027 0.027
ADAMTSL1 N/A 0.027 0.027
ADAMTS19 ADAMTS19: ADAMTS-19 precursor 0.027 0.027
THSD3 N/A 0.027 0.027
ADAMTS20 ADAMTS20: ADAMTS-20 precursor 0.027 0.027
HTRA4 HTRA4: Probable serine protease HTRA4 precursor 0.027 0.027
ADAMTS18 ADAMTS18, ADAMTS21: ADAMTS-18 precursor 0.027 0.027
SLCO5A1 SLCO5A1, SLC21A15: Solute carrier organic anion transporter family member 5A1 0.027 0.027
HTRA3 HTRA3, PRSP: Probable serine protease HTRA3 precursor 0.027 0.027
SMOC1 SMOC1: SPARC-related modular calcium-binding protein 1 precursor 0.027 0.027
UNQ739 VWC2, UNQ739, hCG_2045125, tcag7.1302: von Willebrand factor C domain-containing 0.027 0.027
GDF7 gdf7: Growth differentiation factor 7 0.027 0.027
MT1A MT1A, MT1S: Metallothionein-1A 0.027 0.027
GPHA2 GPHA2, GPA2, ZSIG51: Glycoprotein hormone alpha-2 precursor 0.027 0.265
CNTNAP1 CNTNAP1, CASPR, NRXN4: Contactin-associated protein 1 precursor 0.027 0.027
RTN4RL1 RTN4RL1, NGRH2, NGRL2: Reticulon-4 receptor-like 1 precursor 0.027 0.027
LGI4 LGI4, LGIL3, UNQ6515/PRO21485: Leucine-rich repeat LGI family member 4 precursor 0.027 0.027
LAMA5 0.027 0.027
CHAD CHAD: Chondroadherin precursor 0.027 0.027
BMP4 BMP4, BMP2B, DVR4: Bone morphogenetic protein 4 precursor 0.027 0.027
RTN4RL2 RTN4RL2, NGRH1, NGRL3: Reticulon-4 receptor-like 2 precursor 0.027 0.027
LGI3 LGI3, LGIL4, UNQ8190/PRO23199: Leucine-rich repeat LGI family member 3 precursor 0.027 0.027
NELL2 NELL2, NRP2: Protein kinase C-binding protein NELL2 precursor 0.027 0.027
ROBO1 N/A 0.027 0.027
GDF11 GDF11, BMP11: Growth/differentiation factor 11 precursor 0.027 0.027
FSTL5 FSTL5, KIAA1263: Follistatin-related protein 5 precursor 0.027 0.027
GDF1 GDF1: Embryonic growth/differentiation factor 1 precursor 0.027 0.027
SDC1 SDC1, SDC: Syndecan-1 precursor 0.027 0.074
CETP CETP: Cholesteryl ester transfer protein precursor 0.026 0.026
COL17A1 COL17A1, BP180, BPAG2: Collagen alpha-1(XVII) chain 0.026 0.032
LIPG LIPG, UNQ387/PRO719: Endothelial lipase precursor 0.026 0.032
F5 F5: Coagulation factor V precursor 0.026 0.032
MFAP2 MFAP2, MAGP1: Microfibrillar-associated protein 2 precursor 0.026 0.232
CPM CPM: Carboxypeptidase M precursor 0.026 0.0425
BDKRB2 BDKRB2, BKR2: B2 bradykinin receptor 0.025 0.045
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.025 0.025
OPRD1 OPRD1, OPRD: Delta-type opioid receptor 0.025 0.045
0.299
Total Score 486.00