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Evidence of Interaction Between KPNB1 and RAN

The interaction score between KPNB1 and RAN is 2.02E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between KPNB1 and RAN = 0.81

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 0.027
Orthology
OrganismKPNB1 OrthologueRAN OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YLR347C 1 YLR293C 1
  • Immunoprecipitation
  • Other
  • AffinityChromatography
  • InVitroBinding
  • AffinityCaptureMS
  • AffinityCaptureWestern
  • ReconstitutedComplex

Get References From PubMed
bakers yeast YLR347C 1 YOR185C 0.86
  • AffinityChromatography

Get References From PubMed
worm Q9BIB8 1 O17915 1
fly O18388 1 Q9VZ23 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.593
Domains Domains present in KPNB1 and RAN:
Domains in KPNB1Domains in RAN
IPR000225 Armadillo
IPR001494 Importin-beta, N-terminal
IPR000357 HEAT
IPR011989 ARM-like.
IPR001806 Ras GTPase superfamily
IPR002041 GTP-binding nuclear protein Ran
IPR005225 Small GTP-binding protein domain
IPR013753 Ras

The Chi square scores for co-occurrence of domains that are present in KPNB1 and RAN are listed below.

Domain 1Domain 2Chi Square
IPR011989 ARM-like. IPR001806 Ras GTPase superfamily 0.973757
IPR011989 ARM-like. IPR005225 Small GTP-binding protein domain 0.895278
IPR011989 ARM-like. IPR013753 Ras 0.298074

The background colour of the table refers to:

  • Blue Domain is only present in KPNB1
  • Yellow Domain is only present in RAN
  • Green Domain is present in both KPNB1 and RAN

 0.056
Post-translational Modifications

Protein: KPNB1

PTMResidueReference
N-acetylmethionine 1 HPRD

Protein: RAN

PTMResidueReference
Phosphotyrosine 147 HPRD
Localisation

Protein: KPNB1

LocalisationReference
Nucleus HPRD
Secreted HPRD
Cytoplasm HPRD

Protein: RAN

LocalisationReference
Nucleus HPRD
Mitochondrion HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between KPNB1 and RAN that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between KPNB1 andRAN. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , KPNB1 has 856 interactors and RAN has 1090 interactors of which there are 327 common interactors.

Common InteractorName of Common InteractorScore for KPNB1-Interactor (?)Score for RAN-Interactor (?)
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 115.00 0.141
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 73.00 0.276
RANBP5 32.60 69.60
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 29.70 0.066
KPNA6 N/A 15.90 4.88
NUTF2 NUTF2, NTF2: Nuclear transport factor 2 15.90 1.82
H2AFX H2AFX, H2AX: Histone H2A.x 10.50 0.066
NUP153 N/A 8.74 17.50
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 8.74 0.066
KPNA5 KPNA5: Importin subunit alpha-6 7.31 1.45
KPNA1 KPNA1, RCH2: Importin subunit alpha-1 3.96 0.982
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 3.61 0.129
THUMPD1 N/A 3.05 0.770
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 2.91 0.146
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 2.70 0.036
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 1.62 0.129
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 1.45 0.157
PRKAR2A PRKAR2A, PKR2, PRKAR2: cAMP-dependent protein kinase type II-alpha regulatory su 1.39 0.073
CAT CAT: Catalase 1.33 0.029
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 1.30 0.066
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 1.30 0.066
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 1.20 0.276
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 1.20 23.90
IPO4 IPO4, IMP4B, RANBP4: Importin-4 0.845 0.845
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.795 0.036
DSG2 DSG2: Desmoglein-2 precursor 0.626 0.027
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.549 0.045
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.549 0.385
CSE1L CSE1L, CAS, XPO2: Exportin-2 0.549 145.00
XPO1 XPO1, CRM1: Exportin-1 0.549 202.00
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.549 0.129
MATR3 MATR3, KIAA0723: Matrin-3 0.486 0.0446
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.435 0.233
TIAL1 TIAL1: Nucleolysin TIAR 0.435 0.066
SNRPA SNRPA: U1 small nuclear ribonucleoprotein A 0.435 0.033
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.435 0.141
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.435 0.040
SSB SSB: Lupus La protein 0.435 0.141
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.435 0.066
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.435 0.141
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.435 0.141
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.435 0.032
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.435 0.040
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.435 0.040
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.435 0.066
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.435 0.040
PRKAR2B N/A 0.433 0.181
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.394 0.141
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.372 0.188
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.287 0.430
SRP72 CaM kinase II isoform 0.263 0.038
NUP50 NUP50, NPAP60L, PRO1146: Nucleoporin 50 kDa 0.263 0.123
TNPO1 0.263 19.70
KPNA3 KPNA3: Importin subunit alpha-3 0.263 0.038
ST13 ST13, FAM10A1, HIP, SNC6: Hsc70-interacting protein 0.263 0.038
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.233 1.33
EEF2 EEF2, EF2: Elongation factor 2 0.233 0.063
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.228 0.036
RBM14 RBM14, SIP: RNA-binding protein 14 0.228 0.0446
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.228 0.074
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.228 0.036
AURKB AURKB, AIK2, AIM1, ARK2, STK12: Serine/threonine-protein kinase 12 0.221 0.053
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.204 0.066
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.204 0.040
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.204 0.233
MSN MSN: Moesin 0.188 0.225
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.188 0.171
GTPBP4 GTPBP4, CRFG, NOG1: Nucleolar GTP-binding protein 1 0.179 0.054
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.179 0.917
IPO9 IPO9, IMP9, HSPC273, KIAA1192, RANBP9: Importin-9 0.174 0.140
CDC23 CDC23: Cell division cycle protein 23 homolog 0.160 0.241
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.160 0.129
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.160 0.241
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.160 0.129
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.160 0.372
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.160 0.129
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.160 0.048
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.160 0.188
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.156 0.045
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.156 0.063
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.156 0.038
VCP VCP: Transitional endoplasmic reticulum ATPase 0.146 0.078
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.144 0.704
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.140 0.025
IPO7 IPO7: Uncharacterized protein IPO7 0.140 0.416
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.139 0.225
VIL2 N/A 0.139 0.225
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.139 0.086
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.139 0.129
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.138 0.0446
FANCG FANCG, XRCC9: Fanconi anemia group G protein 0.137 0.042
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.129 0.046
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.127 0.077
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.126 0.114
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.126 0.225
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.126 0.139
DDX21 DDX21: Nucleolar RNA helicase 2 0.125 0.074
NBN NBN, NBS, NBS1, P95: Nibrin 0.125 0.340
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.125 0.074
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.125 0.0446
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.125 0.027
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.123 0.040
RANBP1 RANBP1: Ran-specific GTPase-activating protein 0.123 69.60
BUB1B BUB1B, BUBR1, MAD3L: Mitotic checkpoint serine/threonine-protein kinase BUB1 bet 0.123 0.053
RANBP6 N/A 0.119 0.119
LOC391276 N/A 0.119 0.191
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.112 0.141
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.112 0.066
RBBP4 RBBP4, RBAP48: Histone-binding protein RBBP4 0.112 0.033
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.112 0.066
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.112 0.040
RBM6 RBM6, DEF3: RNA-binding protein 6 0.111 0.027
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.103 0.052
RBM7 0.100 0.040
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.093 0.139
AIP AIP, XAP2: AH receptor-interacting protein 0.093 0.114
CTNNBL1 N/A 0.090 0.0255
RANBP3 N/A 0.083 0.050
BUB3 N/A 0.082 0.027
LRPPRC 0.081 0.081
CAND1 CAND1, KIAA0829, TIP120, TIP120A: Cullin-associated NEDD8-dissociated protein 1 0.081 0.081
SCC-112 N/A 0.081 0.038
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.078 0.146
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.078 0.275
CDK2 CDK2: Cell division protein kinase 2 0.078 0.241
ACTG1 ACTB: Actin, cytoplasmic 1 0.078 3.97
FKBP4 FKBP4: FK506-binding protein 4 0.076 0.139
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.075 0.139
FNBP1 N/A 0.075 0.139
KIAA1012 KIAA1012: Protein TRS85 homolog 0.075 0.038
LOC128322 similar to Nuclear transport factor 2 0.071 0.071
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.070 0.052
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.070 0.048
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.066 0.040
TP53 TP53, P53: Cellular tumor antigen p53 0.066 0.066
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.065 0.276
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.063 0.071
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.063 0.038
GAB1 GAB1: GRB2-associated-binding protein 1 0.062 0.109
ELF1 ELF1: ETS-related transcription factor Elf-1 0.059 0.027
GNB2L1 Lung cancer oncogene 7 0.059 0.0446
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.058 0.069
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.058 0.114
PKP4 PKP4: Plakophilin-4 0.056 0.083
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.056 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.056 0.083
IRS1 IRS1: Insulin receptor substrate 1 0.055 0.109
FUBP1 N/A 0.054 0.087
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.054 0.070
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.054 0.144
SCYE1 SCYE1, EMAP2: Multisynthetase complex auxiliary component p43 [Contains: Endothe 0.053 0.038
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.0525 0.040
PPP1R8 N/A 0.0525 0.040
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.0525 0.066
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.0525 0.066
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.0525 0.066
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.0525 0.040
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.0525 0.141
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.0525 0.040
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.0525 0.111
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.052 0.0425
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.052 0.060
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.052 0.032
AP2B1 AP2B1: Uncharacterized protein AP2B1 0.051 0.191
ROCK1 ROCK1: Rho-associated protein kinase 1 0.051 0.307
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.051 0.087
HD HD, IT15: Huntingtin 0.051 0.210
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.051 0.210
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.050 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.050 0.025
RAB5B RAB5B: Ras-related protein Rab-5B 0.050 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.050 0.025
IPO4 N/A 0.050 0.050
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.048 0.276
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.048 0.515
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.048 0.129
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.048 0.048
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.048 0.129
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.048 0.827
QARS QARS: Glutaminyl-tRNA synthetase 0.048 0.078
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.048 0.146
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.048 0.276
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.048 0.048
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.048 0.048
TCP1 CCT1, CCTA, TCP1: T-complex protein 1 subunit alpha 0.048 0.144
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.048 0.078
HNRPK N/A 0.048 0.078
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.048 4.15
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.048 0.118
LDHB LDHB: L-lactate dehydrogenase B chain 0.048 0.276
CCT8 CCT8: Uncharacterized protein CCT8 0.048 0.276
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.047 0.025
LYN LYN: Tyrosine-protein kinase Lyn 0.046 0.029
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.045 0.372
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.045 0.063
NRAS NRAS, HRAS1: GTPase NRas precursor 0.045 0.078
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.045 0.385
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.045 0.046
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.045 0.275
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.045 0.225
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.045 0.114
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.045 0.029
COPA COPA: Coatomer subunit alpha 0.045 0.046
DSP DSP: Desmoplakin 0.044 0.04
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.0425 0.032
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.0425 0.026
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.041 0.052
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.041 0.210
PCNA PCNA: Proliferating cell nuclear antigen 0.040 0.066
PSEN1 PSEN1, AD3, PS1, PSNL1: Presenilin-1 0.040 0.025
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.040 0.030
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.040 0.030
CASP3 CASP3, CPP32: Caspase-3 precursor 0.039 0.078
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.039 0.048
CFL1 CFL1, CFL: Cofilin-1 0.038 0.046
CNAP1 NCAPD2, CAPD2, CNAP1, KIAA0159: Condensin complex subunit 1 0.038 0.081
CSTF3 CSTF3: Cleavage stimulation factor 77 kDa subunit 0.038 0.081
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.037 0.069
SPAG1 SPAG1: Sperm-associated antigen 1 0.037 0.049
XPO7 XPO7, KIAA0745, RANBP16: Exportin-7 0.037 0.058
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.037 0.157
SET SET: Protein SET 0.037 0.157
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.037 0.157
PTMA N/A 0.037 0.0446
PKP3 PKP3: Plakophilin-3 0.037 0.062
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.071
COPE COPE: Coatomer subunit epsilon 0.037 0.027
PSMD5 PSMD5, KIAA0072: 26S proteasome non-ATPase regulatory subunit 5 0.037 0.037
FLII FLII, FLIL: Protein flightless-1 homolog 0.037 0.071
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.037 0.275
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.037 0.136
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.037 0.171
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.037 0.225
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.037 0.046
VAV1 VAV1, VAV: Proto-oncogene vav 0.037 0.171
PTPN9 0.036 0.036
ARFGAP1 N/A 0.035 0.091
WDR1 N/A 0.035 0.027
MKI67 MKI67: Antigen KI-67 0.035 0.074
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.035 0.074
PLEK PLEK, P47: Pleckstrin 0.035 0.202
IRF3 IRF3: Interferon regulatory factor 3 0.035 0.166
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.035 0.036
CTNND2 CTNND2, NPRAP: Catenin delta-2 0.033 0.050
MCM3 MCM3: DNA replication licensing factor MCM3 0.033 0.141
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.033 0.040
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.033 0.040
CBX3 CBX3: Chromobox protein homolog 3 0.033 0.066
YY1 YY1: Transcriptional repressor protein YY1 0.033 0.032
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.033 0.141
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.033 0.112
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.033 0.040
LSM5 LSM5: U6 snRNA-associated Sm-like protein LSm5 0.033 0.033
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.033 0.066
LSM3 LSM3, MDS017: U6 snRNA-associated Sm-like protein LSm3 0.033 0.033
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.033 0.040
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.033 0.040
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.033 0.423
LSM8 LSM8: U6 snRNA-associated Sm-like protein LSm8 0.033 0.033
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.033 0.040
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.033 0.141
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.033 0.304
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.033 0.066
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.032 0.040
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.032 0.032
ARFGEF2 ARFGEF2, ARFGEP2, BIG2: Brefeldin A-inhibited guanine nucleotide-exchange protei 0.032 0.275
CDC20 CDC20: Cell division cycle protein 20 homolog 0.032 0.141
MTA1 MTA1: Metastasis-associated protein MTA1 0.032 0.040
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.032 0.066
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.032 0.040
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.171
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.032 0.129
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.032 0.171
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.032 0.078
SPTAN1 N/A 0.031 0.034
CIITA CIITA, MHC2TA: MHC class II transactivator 0.030 0.0425
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.030 0.191
ARVCF ARVCF: Armadillo repeat protein deleted in velo-cardio-facial syndrome 0.0296 0.044
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.029 0.069
SHC1 SHC1, RP11-307C12.1-001, hCG_1997126: SHC 0.029 0.038
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.0286 0.0446
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.0286 0.027
GTF2F2 N/A 0.0286 0.027
KIF23 N/A 0.0286 0.0446
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.0286 0.036
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.028
E2IG3 N/A 0.027 0.027
RTCD1 RTCD1, RPC, RPC1, RTC1: RNA 3'-terminal phosphate cyclase 0.027 0.027
SERBP1 N/A 0.027 0.027
ILF2 ILF2, NF45, PRO3063: Interleukin enhancer-binding factor 2 0.027 0.027
NOL7 NOL7, C6orf90, NOP27: Nucleolar protein 7 0.027 0.027
EXOC2 N/A 0.027 0.029
ATM ATM: Serine-protein kinase ATM 0.027 0.069
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.027 0.038
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.027 0.038
DOK1 DOK1: Docking protein 1 0.027 0.171
PSCD4 PSCD4, CYT4: Cytohesin-4 0.027 0.136
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.027 0.086
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.027 0.139
SYMPK SYMPK, SPK: Symplekin 0.027 0.139
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.027 0.136
IPO11 IPO11, RANBP11: Importin-11 0.027 0.027
PTPN13 N/A 0.027 0.027
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.027 0.027
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.0262 0.066
PPL PPL, KIAA0568: Periplakin 0.026 0.034
SAT SAT1, SAT: Diamine acetyltransferase 1 0.026 0.026
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.026 0.066
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.026 0.032
SOS1 SOS1: Son of sevenless homolog 1 0.026 0.113
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.026 0.040
MYBL2 MYBL2, BMYB: Myb-related protein B 0.026 0.066
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.026 0.066
ARHGEF18 ARHGEF18: ARHGEF18 protein 0.0255 0.041
HPRT1 HPRT1, HPRT: Hypoxanthine-guanine phosphoribosyltransferase 0.025 0.025
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.025 0.210
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.025 0.307
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.025 0.307
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.025 0.269
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.025 0.026
ABCF1 N/A 0.025 0.144
API5 N/A 0.025 0.087
CFL2 CFL2: Cofilin-2 0.025 0.025
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.025 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.025
BCR N/A 0.025 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.025 0.047
0.347
Total Score 2.02E4