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Evidence of Interaction Between EPOR and BLNK

The interaction score between EPOR and BLNK is 6.52.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EPOR and BLNK = -0.03

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology N/A N/A
Domains Domains present in EPOR and BLNK:
Domains in EPORDomains in BLNK
IPR003961 Fibronectin, type III
IPR003528 Long hematopoietin receptor, single chain
IPR009167 Erythropoietin receptor
IPR002996 Cytkn_recept_B/G.
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in EPOR and BLNK are listed below.

Domain 1Domain 2Chi Square
IPR002996 Cytkn_recept_B/G. IPR000980 SH2 motif 227.343
IPR003961 Fibronectin, type III IPR000980 SH2 motif 184.508
IPR003528 Long hematopoietin receptor, single chain IPR000980 SH2 motif 151.135
IPR009167 Erythropoietin receptor IPR000980 SH2 motif 38.4825

The background colour of the table refers to:

  • Blue Domain is only present in EPOR
  • Yellow Domain is only present in BLNK
  • Green Domain is present in both EPOR and BLNK

 0.109
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: BLNK

PTMResidueReference
Phosphorylation 72 PubMed, HPRD
Phosphorylation 84 PubMed, HPRD
Phosphorylation 96 PubMed, HPRD
Phosphotyrosine 72 HPRD
Phosphotyrosine 84 HPRD
Phosphotyrosine 96 HPRD
Phosphotyrosine 178 HPRD
Phosphotyrosine 189 HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: BLNK

LocalisationReference
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between EPOR and BLNK that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andBLNK. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and BLNK has 1487 interactors of which there are 651 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for BLNK-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.109
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.541 0.152
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.340 0.127
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.253 0.034
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.251 0.100
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.210 0.166
HSP90AA1 Hsp89-alpha-delta-N 0.202 0.0425
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.065
CRLF3 N/A 0.191 0.126
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.166 0.307
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.166 0.191
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
FN1 N/A 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
BSG N/A 0.165 0.109
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.165 0.980
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.109
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.980
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.165 0.109
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.980
CNTN1 CNTN1: Contactin-1 precursor 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.980
CNTN4 CNTN4: Contactin-4 precursor 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
CAT CAT: Catalase 0.157 0.032
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.153 0.251
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.153 0.123
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.152 0.081
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.152 0.644
KIT KIT: Mast/stem cell growth factor receptor precursor 0.152 0.731
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 0.191
CRKL CRKL: Crk-like protein 0.126 0.251
RDX RDX: Radixin 0.126 0.123
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.152
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.123
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 1.98
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.126 0.041
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.126 0.416
CD2AP CD2AP: CD2-associated protein 0.126 0.852
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.125 0.026
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.125 0.027
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.124 0.191
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.124 0.0425
DCC DCC: Netrin receptor DCC precursor 0.123 0.081
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.072
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.202
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.644
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.072
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.123 0.065
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.123 0.065
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.123 0.581
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.644
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.123 0.644
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.123 0.731
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.123 0.072
GHR GHR: Growth hormone receptor precursor 0.123 0.166
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.123 0.072
INSR INSR: Insulin receptor precursor 0.123 0.644
IL9R IL9R: Interleukin-9 receptor precursor 0.123 0.081
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.202
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.165
MAPK15 N/A 0.109 0.165
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 1.30
PSCD2 N/A 0.109 0.165
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.165
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.165
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.165
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 1.30
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.165
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 0.165
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 0.165
ARHGEF7 N/A 0.109 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.165
ELMO1 N/A 0.109 0.165
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.165
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.165
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 1.30
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.165
NF2 NF2, SCH: Merlin 0.109 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.165
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.540
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 1.30
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 1.30
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.165
STAT3 0.109 0.165
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 0.165
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.109 0.065
F3 F3: Tissue factor precursor 0.109 0.072
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.126
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.065
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 0.731
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.202
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.109 0.581
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.109 0.166
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.072
TNC TNC, HXB: Tenascin precursor 0.109 0.065
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.081
ITGB4 N/A 0.109 0.072
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.581
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.581
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 2.46
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.109 0.654
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.126
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.109 0.581
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.098
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.109 0.081
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.109 0.065
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.109 0.065
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.109 0.065
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.100
SORL1 SORL1: Sortilin-related receptor precursor 0.109 0.126
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.109 0.065
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.307
PRLR PRLR: Prolactin receptor precursor 0.109 0.065
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.109 0.644
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.109 0.902
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.0727
TLN1 TLN1: Uncharacterized protein TLN1 0.100 0.152
DOK1 DOK1: Docking protein 1 0.100 0.251
PLD2 PLD2: Phospholipase D2 0.100 0.123
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.307
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.152
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 0.191
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 4.07
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.152
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 0.975
RPS6KB1 N/A 0.100 0.416
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 3.28
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.100 0.152
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 0.251
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.191
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.098 1.48
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.654
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.098 0.644
PTPRZ1 N/A 0.098 0.065
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.072
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.098 0.065
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.202
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.098 0.0727
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.581
NEO1 NEO1, NGN: Neogenin precursor 0.098 0.0727
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.098 0.644
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.098 0.581
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.098 0.644
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.098 0.0727
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.096 0.027
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.096 0.100
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.091 0.191
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.091 0.251
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.091 0.152
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.091 0.191
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.087 0.037
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.083 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.083 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.083 0.049
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.083 0.109
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.165
ATRN N/A 0.083 0.049
KIR3DL1 N/A 0.083 0.109
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.083 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.083 0.109
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.098
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.191
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.251
DLG2 DLG2: Disks large homolog 2 0.081 0.041
SORBS3 SORBS3, SCAM1: Vinexin 0.081 0.109
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.307
STK16 N/A 0.081 0.191
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.081 0.307
SYK SYK: Tyrosine-protein kinase SYK 0.081 6.73
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.307
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 0.109
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 0.307
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.152
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.109
TLN2 TLN2: Uncharacterized protein TLN2 0.081 0.098
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.051
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.123
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.307
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.191
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.081 0.152
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.081 0.123
HCK N/A 0.081 0.975
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.191
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.081 0.070
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.077 0.032
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.077 0.191
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.077 0.166
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.077 0.100
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.251
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.075 0.307
WEE1 WEE1: Wee1-like protein kinase 0.075 0.191
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.075 0.152
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.075 0.155
CDK2 CDK2: Cell division protein kinase 2 0.075 0.251
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.307
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.416
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.074 0.0425
SPTAN1 N/A 0.0727 0.098
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.123
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.307
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.072 0.109
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.859
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.416
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.191
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.072 0.859
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.072 0.041
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.072 0.045
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.251
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.975
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 0.859
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.072 0.105
TTN N/A 0.072 0.109
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.072 0.041
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.251
VIL2 N/A 0.072 0.416
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.152
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.109
GAB2 N/A 0.072 0.152
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.975
BMX N/A 0.072 0.859
LYN LYN: Tyrosine-protein kinase Lyn 0.072 3.28
MSN MSN: Moesin 0.072 0.191
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 0.859
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.098
FNBP1 N/A 0.072 0.416
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 1.20
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 0.307
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 0.416
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 0.859
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.098
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 2.42
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.072 0.041
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 0.307
PLD1 PLD1: Phospholipase D1 0.072 0.251
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 0.251
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.110
ALK ALK: ALK tyrosine kinase receptor precursor 0.072 0.403
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.123
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 0.975
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.072 0.098
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.098
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 0.191
JAK1 0.072 1.50
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.109
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.109
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.109
CSK CSK: Tyrosine-protein kinase CSK 0.072 4.07
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 1.20
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.123
PSD TYL: TYL protein 0.072 0.098
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.123
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.307
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.251
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.109
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.045
CXorf9 N/A 0.072 0.307
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.251
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.072 0.041
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.109
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.109
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.0688 0.109
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.067 0.402
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.307
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.065 0.975
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.152
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.098
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.098
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.191
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.251
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 0.191
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.123
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.110
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.098
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.123
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.123
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.065 0.098
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 0.123
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.859
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.152
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.100
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.062 0.100
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.062 0.032
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.062 0.081
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.062 0.075
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.062 0.072
CD44 N/A 0.062 0.046
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.062 0.126
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.062 0.202
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.081
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.098
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.027
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.057 0.152
CDK6 CDK6: Cell division protein kinase 6 0.057 0.123
DYRK3 N/A 0.057 0.109
CDK4 CDK4: Cell division protein kinase 4 0.057 0.307
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.057 0.307
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.251
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.056 0.109
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.055 0.202
CD7 CD7: T-cell antigen CD7 precursor 0.055 0.072
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.055 0.202
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.055 0.081
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.055 0.100
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.055 0.100
LILRB1 N/A 0.055 0.202
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.055 0.091
ITGB7 ITGB7: Integrin beta-7 precursor 0.055 0.027
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.055 0.166
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.055 0.340
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.055 0.072
GPA33 GPA33: Cell surface A33 antigen precursor 0.055 0.072
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.055 0.340
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.055 0.166
EGF EGF: Pro-epidermal growth factor precursor 0.055 0.072
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.055 0.072
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.055 0.065
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.055 0.274
ITGAE ITGAE: Integrin alpha-E precursor 0.055 0.0446
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.055 0.072
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.055 0.081
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.055 0.274
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.055 0.065
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.055 0.202
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.055 0.561
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.055 0.100
GNA12 GNA12: Guanine nucleotide-binding protein alpha-12 subunit 0.052 0.027
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.051 0.617
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
GRB10 N/A 0.051 0.051
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
NCAM1 N/A 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.051 0.051
PTPRA N/A 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
EPB41 EPB41, E41P: Protein 4.1 0.051 0.051
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.051
RAPH1 N/A 0.051 0.051
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.051 0.051
C9orf88 N/A 0.051 0.051
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.051 0.051
FLT4 VEGFR3 long form 0.051 0.617
DLG1 DLG1: Disks large homolog 1 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
CRK CRK: Proto-oncogene C-crk 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.100
ST8SIA4 ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe 0.051 0.027
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.051 0.100
TP73 TP73, P73: Tumor protein p73 0.051 0.081
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.0513 0.075
PVR PVR, PVS: Poliovirus receptor precursor 0.049 0.0727
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.049 0.0727
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.049 0.0727
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.049 0.072
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.049 0.100
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.049 0.100
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.049 0.029
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.049 0.065
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.049 0.0688
MAP2K5 N/A 0.049 0.165
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.165
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.049 0.052
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.165
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.165
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.165
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.165
SNX3 N/A 0.049 0.028
CNN2 CNN2: Calponin-2 0.049 0.165
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.165
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.165
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.165
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.083
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.165
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.165
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.165
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.052
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.165
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.049 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.165
MAPKAPK5 N/A 0.049 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.052
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.165
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.052
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.049 0.052
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.049 0.052
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.083
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.049 0.0688
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.049 0.028
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.165
PPEF1 N/A 0.049 0.052
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.165
TSHR N/A 0.048 0.032
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.038
TNN TNN: Tenascin-N precursor 0.047 0.0338
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.046 0.072
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0453 0.191
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.0453 0.070
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.0453 0.152
FUBP1 N/A 0.0453 0.210
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 0.191
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.0453 0.191
DAB1 DAB1: Disabled homolog 1 0.0453 0.098
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.307
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.123
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0453 0.191
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.123
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.0453 0.096
ST6GAL1 ST6GAL1, SIAT1: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltrans 0.045 0.027
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.126
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.166
PLEK PLEK, P47: Pleckstrin 0.045 0.340
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.045 0.166
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.072
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 0.081
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.0446 0.026
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.0446 0.0425
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.0446 0.0425
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.044 0.056
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.065
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.045
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.072
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.100
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.04 0.028
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.04 0.028
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.039 0.027
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.039 0.027
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.038 0.0338
TBCE TBCE: Tubulin-specific chaperone E 0.037 0.032
COPA COPA: Coatomer subunit alpha 0.037 0.070
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.037 0.070
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.037 0.045
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.080
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.110
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.191
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.037 0.515
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.037 0.515
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.152
STK10 STK10: Uncharacterized protein STK10 0.037 0.191
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.045
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.109
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.037 0.191
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.109
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.039
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.152
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.037 0.152
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.037 0.251
FLII FLII, FLIL: Protein flightless-1 homolog 0.037 0.0425
CDK7 CDK7, MO15: Cell division protein kinase 7 0.037 0.251
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.037 0.048
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.037 0.123
CSPG2 N/A 0.037 0.051
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.037 0.032
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.037 0.060
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.037 0.152
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.037 0.123
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.037 0.109
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.109
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.123
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.037 0.416
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.037 0.055
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.037 0.070
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.037 0.152
TK1 TK1: Thymidine kinase, cytosolic 0.036 0.032
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.036 0.052
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.036 0.032
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0338 0.030
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.0338 0.047
CETN1 CETN1, CEN1, CETN: Centrin-1 0.034 0.04
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.034 0.109
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.109
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.109
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.034 0.04
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.033 0.064
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.032 0.109
ATM ATM: Serine-protein kinase ATM 0.032 0.152
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.109
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.034
GMIP GMIP: GEM-interacting protein 0.032 0.096
CDKL5 N/A 0.032 0.110
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.032 0.041
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.515
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.109
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.251
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.032 0.049
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.152
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.307
MYO3A MYO3A: Myosin IIIA 0.032 0.109
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.032 0.096
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.191
ACTN1 ACTN1: Alpha-actinin-1 0.032 0.031
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.032 0.041
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.032 0.041
S100A3 S100A3, S100E: Protein S100-A3 0.032 0.034
DAPK2 DAPK2: Death-associated protein kinase 2 0.032 0.152
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.032 0.034
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.127
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.032 0.098
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.416
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.307
LCP1 LCP1, PLS2: Plastin-2 0.032 0.132
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.416
S100B S100B: Protein S100-B 0.032 0.034
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.032 0.039
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.032 0.031
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.032 0.031
GRLF1 N/A 0.032 0.062
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.032 0.045
VWF VWF, F8VWF: von Willebrand factor precursor 0.032 0.041
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.109
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.032 0.035
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.852
MYL3 MYL3: Myosin light polypeptide 3 0.032 0.034
CHP CHP: Calcium-binding protein p22 0.032 0.039
S100A7 S100A7, PSOR1: Protein S100-A7 0.032 0.039
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.032 0.098
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.109
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.032 0.034
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.123
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.032 0.034
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.109
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.123
PRKAA1 N/A 0.032 0.123
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.123
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 0.152
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.032 0.109
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.416
DAB2 DAB2, DOC2: Disabled homolog 2 0.032 0.123
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.032 0.307
PMP2 PMP2: Myelin P2 protein 0.032 0.055
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.032 0.0971
MELK MELK, KIAA0175: Maternal embryonic leucine zipper kinase 0.032 0.050
TP53 TP53, P53: Cellular tumor antigen p53 0.031 0.0446
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.031 0.027
MDN1 MDN1, KIAA0301: Midasin 0.030 0.0425
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.029 0.041
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.110
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.029 0.041
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.039
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.191
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.098
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.098
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.191
CDK5 CDK5: Cell division protein kinase 5 0.029 0.152
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.123
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.029 0.034
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.029 0.098
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.251
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.029 0.041
CNN3 CNN3: Calponin-3 0.029 0.109
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.029 0.045
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.029 0.031
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.029 0.098
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.110
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.029 0.041
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.191
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.098
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.029 0.051
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.028 0.049
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.109
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.028 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.109
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.049
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.049
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.109
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.049
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.049
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.028 0.04
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
FGFR2 N/A 0.027 0.217
TJP1 TJP1, ZO1: Tight junction protein ZO-1 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.265
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.027 0.217
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.027 0.052
RACGAP1 RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1 0.027 0.032
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.027 0.032
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.027 0.052
THOC1 THOC1, HPR1: THO complex subunit 1 0.027 0.032
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.0263 0.026
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0263 0.087
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.026 0.027
GNB2L1 Lung cancer oncogene 7 0.025 0.036
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.025 0.202
ETS2 ETS2: Protein C-ets-2 0.025 0.100
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.274
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.126
0.228
Total Score 6.52