PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between TP53 and CCNB1

The interaction score between TP53 and CCNB1 is 35.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between TP53 and CCNB1 = 0.71

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.013

Orthology

Organism	TP53 Orthologue		CCNB1 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
fly	Q8IH92	0.16	P20439	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

Domains present in TP53 and CCNB1:

Domains in TP53

Domains in CCNB1

IPR008967	p53-like transcription factor, DNA-binding
IPR002117	p53 tumor antigen
IPR010991	p53, tetramerisation
IPR011615	P53_DNA_bd.
IPR012346	P53_RUNT_DNA_bd.

IPR011028	Cyclin-like
IPR006670	Cyclin
IPR006671	Cyclin, N-terminal
IPR004367	Cyclin, C-terminal
IPR013763	Cyclin-related

The Chi square scores for co-occurrence of domains that are present in TP53 and CCNB1 are listed below.

Domain 1		Domain 2		Chi Square
IPR008967	p53-like transcription factor, DNA-binding	IPR006671	Cyclin, N-terminal	5.01029
IPR008967	p53-like transcription factor, DNA-binding	IPR006670	Cyclin	4.6783
IPR010991	p53, tetramerisation	IPR006671	Cyclin, N-terminal	4.58466
IPR012346	P53_RUNT_DNA_bd.	IPR006671	Cyclin, N-terminal	4.58466
IPR011615	P53_DNA_bd.	IPR006671	Cyclin, N-terminal	4.58466
IPR002117	p53 tumor antigen	IPR006671	Cyclin, N-terminal	4.58466
IPR002117	p53 tumor antigen	IPR006670	Cyclin	2.92461
IPR012346	P53_RUNT_DNA_bd.	IPR006670	Cyclin	2.92461
IPR011615	P53_DNA_bd.	IPR006670	Cyclin	2.92461
IPR010991	p53, tetramerisation	IPR006670	Cyclin	2.92461
IPR008967	p53-like transcription factor, DNA-binding	IPR011028	Cyclin-like	0.663281
IPR008967	p53-like transcription factor, DNA-binding	IPR013763	Cyclin-related	0.604607
IPR012346	P53_RUNT_DNA_bd.	IPR011028	Cyclin-like	0.459235
IPR011615	P53_DNA_bd.	IPR011028	Cyclin-like	0.459235
IPR010991	p53, tetramerisation	IPR011028	Cyclin-like	0.459235
IPR002117	p53 tumor antigen	IPR011028	Cyclin-like	0.459235
IPR002117	p53 tumor antigen	IPR013763	Cyclin-related	0.418093
IPR010991	p53, tetramerisation	IPR013763	Cyclin-related	0.418093
IPR011615	P53_DNA_bd.	IPR013763	Cyclin-related	0.418093
IPR012346	P53_RUNT_DNA_bd.	IPR013763	Cyclin-related	0.418093

The background colour of the table refers to:

Blue Domain is only present in TP53
Yellow Domain is only present in CCNB1
Green Domain is present in both TP53 and CCNB1

0.083

Post-translational Modifications

Protein: TP53

PTM	Residue	Reference
Acetylation	305	PubMed, HPRD
Acetylation	320	PubMed, HPRD
Acetylation	370	PubMed, HPRD
Acetylation	372	PubMed, HPRD
Acetylation	373	PubMed, HPRD
Acetylation	381	PubMed, HPRD
Acetylation	382	PubMed, HPRD
Deacylation	382	PubMed, HPRD
Dephosphorylation	315	PubMed, HPRD
N6-acetyllysine	305	HPRD
N6-acetyllysine	373	HPRD
N6-acetyllysine	382	HPRD
Phosphorylation	6	PubMed, HPRD
Phosphorylation	9	PubMed, HPRD
Phosphorylation	15	PubMed, HPRD
Phosphorylation	18	PubMed, HPRD
Phosphorylation	20	PubMed, HPRD
Phosphorylation	33	PubMed, HPRD
Phosphorylation	37	PubMed, HPRD
Phosphorylation	46	PubMed, HPRD
Phosphorylation	55	PubMed, HPRD
Phosphorylation	81	PubMed, HPRD
Phosphorylation	155	PubMed, HPRD
Phosphorylation	315	PubMed, HPRD
Phosphorylation	366	PubMed, HPRD
Phosphorylation	371	PubMed, HPRD
Phosphorylation	378	PubMed, HPRD
Phosphorylation	392	PubMed, HPRD
Phosphoserine	15	PubMed, HPRD
Phosphoserine	46	PubMed, HPRD
Phosphoserine	315	PubMed, HPRD
Phosphothreonine	18	PubMed, HPRD
Phosphothreonine	55	PubMed, HPRD
Proteolytic Cleavage	18	PubMed, HPRD
Proteolytic Cleavage	20	PubMed, HPRD
Proteolytic Cleavage	23	PubMed, HPRD
Sumoylation	386	PubMed, HPRD
Ubiquitination	351	PubMed, HPRD
Ubiquitination	357	PubMed, HPRD
Ubiquitination	370	PubMed, HPRD
Ubiquitination	372	PubMed, HPRD
Ubiquitination	373	PubMed, HPRD
Ubiquitination	381	PubMed, HPRD
Ubiquitination	382	PubMed, HPRD
Ubiquitination	386	PubMed, HPRD

Protein: CCNB1

PTM	Residue	Reference
Phosphorylation	126	PubMed, HPRD
Phosphorylation	128	PubMed, HPRD
Phosphorylation	133	PubMed, HPRD
Phosphorylation	147	PubMed, HPRD

Localisation

Protein: TP53

Localisation	Reference
ER	HPRD
Nucleus	HPRD
Mitochondrion	HPRD
Nucleolus	HPRD
Cytoplasm	HPRD

Protein: CCNB1

Localisation	Reference
Nucleus	HPRD
Plasma membrane	HPRD
Nucleolus	HPRD
Centrosome	HPRD
Cytoplasm	HPRD
Cytoskeleton	HPRD

Transitive Score

The common interactors between TP53 and CCNB1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andCCNB1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and CCNB1 has 1142 interactors of which there are 812 common interactors.

Common Interactor	Name of Common Interactor	Score for TP53-Interactor (?)	Score for CCNB1-Interactor (?)
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	4.77	0.260
H2AFX	H2AFX, H2AX: Histone H2A.x	4.27	0.276
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	2.54	0.029
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	2.08	0.136
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	1.58	0.086
HIST1H1B	HIST1H1B, H1F5: Histone H1.5	1.26	0.111
PGR	PGR, NR3C3: Progesterone receptor	1.00	0.055
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.964	0.471
NR4A2	NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2	0.902	0.044
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.822	0.385
PCNA	PCNA: Proliferating cell nuclear antigen	0.704	0.822
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.704	0.063
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.704	0.139
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.651	0.127
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.541	0.0446
SP100	N/A	0.525	0.096
MCM3	MCM3: DNA replication licensing factor MCM3	0.515	40.60
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.503	0.040
SREBF2	N/A	0.475	0.052
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.471	0.078
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.430	0.210
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.430	0.155
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.430	0.144
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.430	0.307
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.430	0.070
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.430	0.233
DDX21	DDX21: Nucleolar RNA helicase 2	0.430	0.070
NBN	NBN, NBS, NBS1, P95: Nibrin	0.430	0.155
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.430	0.260
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.425	0.046
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.385	0.063
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.385	0.188
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.385	0.822
SP3	SP3: Transcription factor Sp3	0.347	0.114
SRF	SRF: Serum response factor	0.344	0.046
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.318	0.171
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.304	7.30
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.290	0.038
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.284	0.225
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.276
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.276	0.078
POLA2	POLA2: DNA polymerase subunit alpha B	0.276	0.078
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.276	0.129
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.276	0.078
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.276	0.078
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.276	0.078
CENPA	CENPA: Histone H3-like centromeric protein A	0.269	0.307
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.260	0.052
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.260	0.763
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.260	0.155
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.260	0.260
GGCX	GGCX, GC: Vitamin K-dependent gamma-carboxylase	0.254	0.038
EP300	N/A	0.254	0.029
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.253	0.0446
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.245	0.066
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.241	0.385
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.241	1.62
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.241	1.62
POLR2H	POLR2H: DNA-directed RNA polymerases I, II, and III subunit RPABC3	0.241	0.045
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.233	0.188
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.233	0.063
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.233	0.038
YY1	YY1: Transcriptional repressor protein YY1	0.233	0.139
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.233	0.038
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.233	0.188
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.227	0.066
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.216	0.056
ELF1	ELF1: ETS-related transcription factor Elf-1	0.210	0.191
MATR3	MATR3, KIAA0723: Matrin-3	0.210	0.155
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.210	0.070
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.210	0.086
RB1	RB1: Retinoblastoma-associated protein	0.210	0.416
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.208	0.086
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.188	0.225
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.188	0.038
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.188	0.372
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.188	0.038
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.188	0.086
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.188	0.038
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.188	1.08
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.188	0.038
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.188	0.139
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.188	0.046
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.187	0.025
MYB	MYB: Myb proto-oncogene protein	0.176	0.127
CEBPE	CEBPE: CCAAT/enhancer-binding protein epsilon	0.172	0.069
CEBPB	CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta	0.172	0.044
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.162	0.061
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.156	0.055
TP73	TP73, P73: Tumor protein p73	0.156	0.062
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.155	0.062
ZNF267	ZNF267: Zinc finger protein 267	0.155	0.096
ERF	ERF: ETS domain-containing transcription factor ERF	0.155	0.191
XRCC1	XRCC1: DNA-repair protein XRCC1	0.155	0.127
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.155	0.096
MITF	MITF: Microphthalmia-associated transcription factor	0.152	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.152	0.028
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.152	0.083
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.152	0.028
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.146	0.385
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.146	0.038
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.146	0.233
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.146	86.60
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.146	0.372
PPP2CA	PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	0.145	0.051
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.144	0.251
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.144	0.087
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.144	0.087
ESPL1	N/A	0.144	0.307
PTMA	N/A	0.144	0.070
ABCF1	N/A	0.144	0.070
MKI67	MKI67: Antigen KI-67	0.144	0.307
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.087
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.141	0.040
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.141	0.040
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.141	0.032
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.141	0.141
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.141	0.066
LEF1	LEF1: Lymphoid enhancer-binding factor 1	0.140	0.069
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.139	0.063
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.139	0.038
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.139	0.029
COPE	COPE: Coatomer subunit epsilon	0.139	0.038
RELA	RELA, NFKB3: Transcription factor p65	0.139	0.086
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.139	0.078
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.139	0.136
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.139	0.233
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.139	0.029
CDC23	CDC23: Cell division cycle protein 23 homolog	0.137	2.12
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.137	7.88
LMNA	LMNA, LMN1: Lamin-A/C	0.137	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.137	0.025
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.137	0.025
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.137	0.075
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.132	0.210
IRF3	IRF3: Interferon regulatory factor 3	0.132	0.152
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.132	0.852
CBX3	CBX3: Chromobox protein homolog 3	0.129	0.233
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.129	0.129
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.078
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.129
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.078
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.078
NUP153	N/A	0.129	0.078
SSB	SSB: Lupus La protein	0.129	0.078
KIF11	N/A	0.129	0.276
CDC20	CDC20: Cell division cycle protein 20 homolog	0.129	0.827
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.129	0.129
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.129	0.129
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	1.62
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.129	0.063
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.129	0.461
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.063
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.078
CDK4	CDK4: Cell division protein kinase 4	0.129	0.763
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.129	0.046
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.129	0.129
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.129	0.372
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.129	0.078
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.129	0.078
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.129
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.129	6.86
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.078
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.188
ZFX	ZFX: Zinc finger X-chromosomal protein	0.127	0.077
HIVEP1	N/A	0.127	0.096
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.127	0.077
ZNF335	ZNF335: Zinc finger protein 335	0.127	0.069
SALL1	SALL1, SAL1: Sal-like protein 1	0.125	0.050
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.124	12.00
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.118	0.171
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.118	0.763
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.118	0.139
CCNH	CCNH: Cyclin-H	0.114	0.171
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.114	0.069
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.114	0.035
MTF1	MTF1: Metal regulatory transcription factor 1	0.114	0.086
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.114	0.111
TRIM25	TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25	0.114	0.054
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.114	0.069
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.114	0.225
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.114	0.029
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.114	0.086
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.114	0.038
FKBP4	FKBP4: FK506-binding protein 4	0.114	0.046
ETS1	ETS1, EWSR2: Protein C-ets-1	0.114	0.111
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.114	0.038
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.114	0.029
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.114	0.275
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.114	0.056
CSK	CSK: Tyrosine-protein kinase CSK	0.112	0.051
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.112	0.067
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.112	0.111
ZBTB16	ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16	0.111	0.050
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.111	0.040
HSP90AA1	Hsp89-alpha-delta-N	0.111	0.040
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.111	0.051
STAT6	STAT6: Signal transducer and activator of transcription 6	0.111	0.041
HDAC4	HDAC4, KIAA0288: Histone deacetylase 4	0.102	0.0308
GTF2F2	N/A	0.0971	0.307
PSMD3	PSMD3: 26S proteasome non-ATPase regulatory subunit 3	0.0968	0.099
EEA1	EEA1, ZFYVE2: Early endosome antigen 1	0.096	0.056
NFATC1	N/A	0.096	0.062
STAT2	STAT2: Signal transducer and activator of transcription 2	0.096	0.026
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.096	0.087
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.093	0.032
SATB2	SATB2, KIAA1034: DNA-binding protein SATB2	0.090	0.028
DNMT1	DNMT1, AIM, DNMT: DNA	0.087	0.087
TGIF2	TGIF2: Homeobox protein TGIF2	0.087	0.080
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.087	0.096
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.087	0.087
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.087	0.070
UNG	N/A	0.087	0.078
SET	SET: Protein SET	0.087	0.087
RBM14	RBM14, SIP: RNA-binding protein 14	0.087	0.070
TCOF1	N/A	0.087	0.070
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.087	0.416
GNB2L1	Lung cancer oncogene 7	0.087	0.052
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.087	0.0425
NCOA3	N/A	0.087	0.026
KIF23	N/A	0.087	0.144
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.070
IFI16	N/A	0.087	0.032
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.087	0.139
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.087	0.046
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.087	0.225
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.086	0.136
MLL	MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX	0.086	0.069
BRPF1	BRPF1, BR140: Peregrin	0.086	0.069
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.086	0.069
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.086	0.995
CCND1	CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1	0.086	0.136
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.086	0.069
ATM	ATM: Serine-protein kinase ATM	0.086	0.049
SOX4	SOX4: Transcription factor SOX-4	0.086	0.069
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.086	0.097
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.084	0.0446
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.083	0.083
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.083	0.165
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.083	0.083
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.083	0.083
UHRF1		0.083	0.083
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.083	0.083
EEF2K	EEF2K: Elongation factor 2 kinase	0.083	0.075
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.083	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.083	0.083
ZNF579	ZNF579: Zinc finger protein 579	0.083	0.083
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.083	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.083	0.083
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.083	0.083
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.165
PPEF1	N/A	0.083	0.083
MAPK15	N/A	0.083	0.165
C20orf18	N/A	0.083	0.052
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.083	0.083
TRAP1	TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor	0.0818	0.032
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.0818	0.051
HIPK2	HIPK2: Homeodomain-interacting protein kinase 2	0.081	0.097
H1FX	H1FX: Histone H1x	0.080	0.152
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.078	0.063
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.078	0.078
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.078	0.078
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.078	0.276
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.046
LIG1	LIG1: DNA ligase 1	0.078	0.129
NOL1	N/A	0.078	0.063
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.372
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.078	2.47
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.078	0.046
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.046
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.078	0.063
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	86.60
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.188
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.275
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.046
CDK7	CDK7, MO15: Cell division protein kinase 7	0.078	0.372
MYBL2	MYBL2, BMYB: Myb-related protein B	0.078	0.385
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.078	0.114
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.078	0.146
TIAL1	TIAL1: Nucleolysin TIAR	0.078	0.063
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.046
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.063
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.046
FNBP1	N/A	0.078	0.029
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.078	0.063
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.078	0.046
CDK2	CDK2: Cell division protein kinase 2	0.078	21.70
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.078	0.063
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.078	0.046
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.038
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.078	0.078
ERG	ERG: Transcriptional regulator ERG	0.077	0.152
MDM4	MDM4, MDMX: Mdm4 protein	0.077	0.039
SNAI1	SNAI1, SNAH: Zinc finger protein SNAI1	0.077	0.056
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.077	0.077
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.077	0.026
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.077	0.096
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.077	0.029
ETS2	ETS2: Protein C-ets-2	0.077	0.123
CCNT2	CCNT2: Cyclin-T2	0.075	0.148
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.075	0.148
GIT2	N/A	0.075	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.075	0.075
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.075	0.075
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.075	0.025
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.075	0.075
RBL1	RBL1: Retinoblastoma-like protein 1	0.075	0.148
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.075	0.075
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.075	0.047
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.075	0.148
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.075	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.075	0.075
RNF20		0.075	0.047
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.075	0.047
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.075	0.148
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.075	0.148
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.075	0.047
BRD4	N/A	0.075	0.025
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.075	0.075
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.075	0.075
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.075	0.075
SOX8	SOX8: Transcription factor SOX-8	0.075	0.075
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.075	0.025
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.074	0.046
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.253
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.074	0.032
PHB2	PHB2, BAP, REA: Prohibitin-2	0.074	0.274
PTTG1	PTTG1, EAP1, PTTG, TUTR1: Securin	0.0727	0.053
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.071	0.136
API5	N/A	0.070	0.070
UBAP2	N/A	0.070	0.087
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.052
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.0425
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.0425
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.070	0.070
WDR1	N/A	0.070	0.032
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.070	0.191
STK16	N/A	0.070	0.307
PLEK	PLEK, P47: Pleckstrin	0.070	0.026
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.070	0.144
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.070	0.087
KIAA0853	N/A	0.070	0.052
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.052
TCF8	ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1	0.069	0.044
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.069	0.188
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	0.069	0.088
FOS	FOS, G0S7: Proto-oncogene protein c-fos	0.069	0.049
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.069	0.086
ZNF551	N/A	0.069	0.069
LIG4	LIG4: DNA ligase 4	0.069	0.056
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.069	0.056
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.067	0.051
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.067	0.051
PPP1CB	PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit	0.067	0.041
SYK	SYK: Tyrosine-protein kinase SYK	0.067	0.033
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.040
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.066	0.040
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.066	0.032
CTPS	CTPS: CTP synthase 1	0.066	0.066
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.040
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.066
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.066	1.26
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.066	0.040
HNRPK	N/A	0.066	0.032
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.066	0.066
MTHFD1	MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic	0.066	0.040
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.066	0.032
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.066	0.040
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.066	0.032
HSPD1		0.066	0.066
CSE1L	CSE1L, CAS, XPO2: Exportin-2	0.066	0.033
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.141
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.066	0.111
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.063	0.029
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.063	0.046
MYH9	MYH9: Myosin-9	0.063	0.029
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.078
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.046
COPB2	COPB2: Coatomer subunit beta'	0.063	0.063
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.063	0.029
HDAC2	HDAC2: Histone deacetylase 2	0.063	0.233
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.063	0.763
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.038
COPA	COPA: Coatomer subunit alpha	0.063	0.038
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.086
WEE1	WEE1: Wee1-like protein kinase	0.063	0.385
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.063	0.225
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.063	0.129
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.063	0.046
PPP1R8	N/A	0.063	0.046
MTA1	MTA1: Metastasis-associated protein MTA1	0.063	0.139
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.063
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.038
CORO1C	CORO1C, CRNN4: Coronin-1C	0.063	0.038
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.063	0.038
SEC31L1	N/A	0.063	0.038
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.029
RBM7		0.063	0.046
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.038
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.139
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.063
RPS6KB1	N/A	0.063	0.225
PHF10	N/A	0.063	0.139
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.063	0.385
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.063	0.136
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.029
WBSCR20A	N/A	0.063	0.029
SH3BP3		0.062	0.055
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.062	0.077
ZBTB33	KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso	0.062	0.062
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.062	0.096
LYN	LYN: Tyrosine-protein kinase Lyn	0.061	0.027
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.061	0.030
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.061	0.057
FOXO1A	FOXO1A, FKHR: Forkhead box protein O1A	0.060	2.77
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.060	0.191
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.057	0.073
MYCBP2	MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2	0.056	0.046
FOSL2	FOSL2, FRA2: Fos-related antigen 2	0.056	0.044
SP1	SP1, TSFP1: Transcription factor Sp1	0.056	0.069
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.056	0.056
CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL	0.056	0.035
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.056	0.056
PCAF	PCAF: Histone acetyltransferase PCAF	0.056	0.038
ETV1	ETV1, ER81: ETS translocation variant 1	0.056	0.098
STAT4	STAT4: Signal transducer and activator of transcription 4	0.055	0.044
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.055	0.048
TAF1	TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1	0.055	0.026
SOS1	SOS1: Son of sevenless homolog 1	0.054	0.056
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.054	0.086
RPA1	RPA1, REPA1, RPA70: Replication protein A 70 kDa DNA-binding subunit	0.053	0.038
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.052	0.165
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.052	0.165
ROCK1	ROCK1: Rho-associated protein kinase 1	0.052	0.191
EMD	EMD, EDMD, STA: Emerin	0.052	0.0425
TRRAP	N/A	0.052	0.0425
ARFGAP1	N/A	0.052	0.0425
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.026
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.052	0.096
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.052	0.0425
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.052	0.0425
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.052	0.0425
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.052	0.032
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.052	0.052
CHUK	N/A	0.052	0.0425
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.052	0.052
AFF1	N/A	0.052	0.0425
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.052	0.127
TOP2B	N/A	0.052	0.0425
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.052	0.032
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.051	0.033
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.051	0.090
JAK1		0.051	0.029
RNF11	RNF11, CGI-123: RING finger protein 11	0.050	0.0308
SMARCA1	SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1	0.050	0.044
ZHX3	ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3	0.049	0.056
SF3A3	SF3A3, SAP61: Splicing factor 3A subunit 3	0.049	0.036
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.049	0.109
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.049	0.109
TRIM39	TRIM39, RNF23, TFP: Tripartite motif-containing protein 39	0.049	0.04
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	0.049	0.088
SOX11	SOX11: Transcription factor SOX-11	0.049	0.049
KLF5	KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5	0.049	0.056
ELK1	ELK1: ETS domain-containing protein Elk-1	0.049	0.111
BNC1	BNC1, BNC: Zinc finger protein basonuclin-1	0.049	0.056
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.048	0.077
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.048	0.077
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.048	0.191
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.047	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.047	0.025
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.047	0.148
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.047	0.075
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.047	0.148
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.047	0.025
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.046	0.029
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.046	0.029
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.029
DIAPH1	Diaphanous 1	0.046	1.53
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.046	0.136
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.046	0.171
DOK1	DOK1: Docking protein 1	0.046	0.029
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.029
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.046	0.171
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.086
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.046	0.078
KLHDC4	N/A	0.046	0.029
WDR79	N/A	0.046	0.046
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.046	0.038
CRSP2	MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol	0.046	0.038
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.046	0.171
CUL4B	N/A	0.046	0.029
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.046	0.171
ARMET	ARMET, ARP: Protein ARMET precursor	0.046	0.038
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.046	0.136
GSK3B	N/A	0.046	0.029
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.046	0.171
SYMPK	SYMPK, SPK: Symplekin	0.046	0.038
CUL5	CUL5, VACM1: Cullin-5	0.046	0.029
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.046	0.038
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.046	0.136
SAPS3	N/A	0.046	0.038
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.046	0.233
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.046	0.461
MDN1	MDN1, KIAA0301: Midasin	0.046	0.114
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.046	0.171
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.046	0.171
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.046	0.038
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.046	0.129
FZR1	N/A	0.046	2.47
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.046	0.233
PPP2CB	PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	0.0462	0.026
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.046	0.100
LMAN1	LMAN1, ERGIC53, F5F8D: Protein ERGIC-53 precursor	0.046	0.028
BIRC4	BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4	0.0453	0.046
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.0446	0.472
TK1	TK1: Thymidine kinase, cytosolic	0.0446	0.141
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.0446
EGR1	EGR1, ZNF225: Early growth response protein 1	0.044	0.044
VDR	VDR, NR1I1: Vitamin D3 receptor	0.043	0.056
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.043	11.90
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.0425	0.026
SMARCC2	N/A	0.0425	0.032
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.0425	0.123
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.0425	0.055
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.0425	0.191
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.0425	0.063
COIL	COIL, CLN80: Coilin	0.0425	0.032
RBM6	RBM6, DEF3: RNA-binding protein 6	0.0425	0.032
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.0425	0.026
XRCC4	N/A	0.0425	0.032
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.0425	0.048
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.0425	0.096
CDKN1A	CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi	0.0425	0.191
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.0425	0.096
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.0425	0.127
DHX15	DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase	0.042	0.0255
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.041	0.029
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	0.041	0.032
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.04	0.049
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.04	0.04
THOP1	THOP1: Thimet oligopeptidase	0.040	0.032
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.040	0.032
ENO1	ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase	0.040	0.032
TRIP13	TRIP13: Thyroid receptor-interacting protein 13	0.040	0.484
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.040	0.032
XPO1	XPO1, CRM1: Exportin-1	0.040	0.040
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.040	0.141
LDHB	LDHB: L-lactate dehydrogenase B chain	0.040	0.032
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.040	0.137
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.040
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.040	0.185
PPARG	CREB3L2-PPARgamma	0.039	0.049
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	0.039	0.055
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.038	0.086
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.038	0.225
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.038	0.029
STK10	STK10: Uncharacterized protein STK10	0.038	0.111
MAFG	MAFG: Transcription factor MafG	0.038	0.139
TCEB3	TCEB3, MSTP059: Transcription elongation factor B polypeptide 3	0.038	0.171
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.038	1.53
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.029
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.038	0.043
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.038	0.111
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.038	0.111
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.038	0.111
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.038	0.038
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.038	0.029
ARID3A	ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein	0.038	0.171
CCNG1	CCNG1, CCNG, CYCG1: Cyclin-G1	0.038	0.074
CCNA2	CCNA2, CCN1, CCNA: Cyclin-A2	0.038	0.789
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.037	0.037
YES1	YES1, YES: Proto-oncogene tyrosine-protein kinase Yes	0.037	0.041
E2F5	E2F5: Transcription factor E2F5	0.036	0.028
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.027
SRPR	SRPR: Uncharacterized protein SRPR	0.036	0.057
HD	HD, IT15: Huntingtin	0.036	0.061
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.036	0.044
PTK2B	PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta	0.036	0.036
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.036	0.044
MYST4	MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4	0.035	0.097
H1F0	H1F0, H1FV: Histone H1.0	0.035	0.093
FOXL2	FOXL2: Forkhead box protein L2	0.034	0.097
AXL	AXL, UFO: Tyrosine-protein kinase receptor UFO precursor	0.034	0.0688
HCK	N/A	0.033	0.029
ZAP70	ZAP70: Uncharacterized protein ZAP70	0.033	0.029
FER	FER, TYK3: Proto-oncogene tyrosine-protein kinase FER	0.033	0.051
INSL3	JAK3: Tyrosine-protein kinase JAK3	0.032	0.081
ID2	ID2: DNA-binding protein inhibitor ID-2	0.032	0.055
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.032	0.032
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.032	0.123
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.032	0.123
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.032	0.032
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.032	0.062
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.032	0.062
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.032	0.077
AHR	AHR: Aryl hydrocarbon receptor precursor	0.032	0.056
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.032	0.155
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.123
BACH1	BACH1: Transcription regulator protein BACH1	0.032	0.062
CASP3	CASP3, CPP32: Caspase-3 precursor	0.032	0.111
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.032	1.03
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.032	0.040
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.032	0.032
CRKL	CRKL: Crk-like protein	0.032	0.032
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.032	0.032
PRDX1	PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1	0.032	0.032
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.032	0.032
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.032	0.040
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.032	0.181
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.032	0.067
CUL2	CUL2: Cullin-2	0.032	0.076
NR1D1	NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1	0.031	0.044
ESR1	ESR1, ESR, NR3A1: Estrogen receptor	0.031	0.055
RFX1	RFX1: MHC class II regulatory factor RFX1	0.0308	0.097
HIST1H1A	HIST1H1A, H1F1: Histone H1.1	0.0308	0.111
PTPRF	PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor	0.030	0.030
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.029	0.097
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.029	0.056
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.029	0.111
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.029	0.046
TOP3A	TOP3A, TOP3: DNA topoisomerase 3-alpha	0.029	0.038
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.029	0.063
JUNB	JUNB: Transcription factor jun-B	0.029	0.049
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.029	0.171
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.029	0.097
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.029	0.275
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.029	0.029
METTL1	METTL1, C12orf1: tRNA	0.029	0.038
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.029	0.069
JUND	JUND: Transcription factor jun-D	0.029	0.049
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.029
SMCX	JARID1C, DXS1272E, SMCX, XE169: Histone demethylase JARID1C	0.029	0.171
CSDA	CSDA, DBPA: DNA-binding protein A	0.029	0.046
ATF6	ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha	0.029	0.056
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.052
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
C13orf8	N/A	0.028	0.028
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.028	0.075
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
IRF7	N/A	0.028	0.028
WDR54	N/A	0.028	0.028
DUSP15	N/A	0.028	0.028
RAB4A	N/A	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.083
PHLDB2	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
KIF1B	N/A	0.028	0.028
HDAC8	N/A	0.028	0.083
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.083
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
TFAP4	TFAP4: Transcription factor AP-4	0.028	0.075
CDC2	CDC2: Cell division control protein 2 homolog	0.028	0.148
CORO6	N/A	0.028	0.028
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.028	0.148
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.083
NES	N/A	0.028	0.025
SNRPB	N/A	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.028	0.148
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.028
MAPKAPK5	N/A	0.028	0.083
CABLES1	N/A	0.028	0.028
HDAC7A	N/A	0.028	0.047
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
FLJ23436	N/A	0.028	0.025
DSP	DSP: Desmoplakin	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.083
BID	BID: BH3-interacting domain death agonist	0.028	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.083
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.165
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
NF2	NF2, SCH: Merlin	0.028	0.028
HES6	HES6: Transcription cofactor HES-6	0.028	0.052
ZNF265	N/A	0.028	0.028
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.028	0.148
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.052
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
PRKACB	PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit	0.028	0.056
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.165
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.165
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.028	0.075
EPHA2	EPHA2, ECK: Ephrin type-A receptor 2 precursor	0.028	0.028
RFX5	RFX5: DNA-binding protein RFX5	0.0278	0.050
NR4A1	CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor	0.028	0.044
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	0.027	0.033
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.027	0.026
FRK	FRK, PTK5, RAK: Tyrosine-protein kinase FRK	0.027	0.033
FXR2	FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2	0.027	0.033
C20orf116	C20orf116: Uncharacterized protein C20orf116 precursor	0.027	0.027
YWHAQ	YWHAQ: 14-3-3 protein theta	0.027	0.027
BMX	N/A	0.0263	0.032
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.032
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.0425
TRIM16	TRIM16, EBBP: Tripartite motif-containing protein 16	0.026	0.048
PCTK1	PCTK1: Serine/threonine-protein kinase PCTAIRE-1	0.026	0.171
KRT18	KRT18: Uncharacterized protein KRT18	0.026	0.026
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.026	0.251
PRKAA1	N/A	0.026	0.152
GRLF1	N/A	0.026	0.026
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.026	0.026
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.026	0.123
CIC	CIC, KIAA0306: Protein capicua homolog	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.148
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.047
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.148
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.047
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.148
PRKCB1	N/A	0.025	0.714
CREB1	CREB1: cAMP response element-binding protein	0.025	0.075
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.148
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.075
ATXN2L	N/A	0.025	0.025
ELMO1	N/A	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.047
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
GRK6	N/A	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
NUP98	N/A	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
SEC13L1	N/A	0.025	0.025
NIPBL	N/A	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.075
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.148
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
C20orf77	N/A	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.148
ADK	ADK: Adenosine kinase	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.075
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.148
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
HTATIP	N/A	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.075
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
DIDO1	N/A	0.025	0.075
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
CAMK2A	N/A	0.025	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.025	7.88
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.075
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.148
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.148
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.148
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	1.33
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
TCEA1	N/A	0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.075
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	4.22
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.148
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.148
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
SON		0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.075
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.148
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.025	0.148
BCOR	N/A	0.025	0.025
CAMKK1	N/A	0.025	1.33
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.148
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.075
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
KCTD1		0.025	0.025
MAPK8IP3	N/A	0.025	0.025
MAX	MAX: Protein max	0.025	0.047
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.025	0.148
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.148
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.075
PTGES3	PTGES3, P23, TEBP: Prostaglandin E synthase 3	0.025	0.025
KNTC2	KNTC2, HEC, HEC1: Kinetochore protein Hec1	0.025	0.0479

0.228

Total Score

35.00