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Evidence of Interaction Between CBL and GRB2

The interaction score between CBL and GRB2 is 1.91E3.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismCBL OrthologueGRB2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00292856 0.232 IPI00013864 0.559
worm Q19019 0.232 P29355 1
  • Other

Get References From PubMed
fly Q9VSK2 0.118 Q08012 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.191
Domains Domains present in CBL and GRB2:
Domains in CBLDomains in GRB2
IPR001841 Zn-finger, RING
IPR000449 Ubiquitin-associated domain
IPR000980 SH2 motif
IPR000217 Tubulin
IPR003153 Adaptor protein Cbl, N-terminal
IPR011992 EF-Hand_type.
IPR013090 Phospholip_A2_AS.
IPR001452 SH3
IPR000108 Neutrophil cytosol factor 2
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in CBL and GRB2 are listed below.

Domain 1Domain 2Chi Square
IPR000980 SH2 motif IPR001452 SH3 59.5667
IPR000980 SH2 motif IPR000980 SH2 motif 36.445
IPR003153 Adaptor protein Cbl, N-terminal IPR000980 SH2 motif 26.7596
IPR000980 SH2 motif IPR000108 Neutrophil cytosol factor 2 21.5484
IPR003153 Adaptor protein Cbl, N-terminal IPR001452 SH3 20.2778
IPR001841 Zn-finger, RING IPR001452 SH3 18.8486
IPR003153 Adaptor protein Cbl, N-terminal IPR000108 Neutrophil cytosol factor 2 17.4696
IPR011992 EF-Hand_type. IPR001452 SH3 11.7553
IPR001841 Zn-finger, RING IPR000980 SH2 motif 9.93803
IPR011992 EF-Hand_type. IPR000980 SH2 motif 5.54712
IPR001841 Zn-finger, RING IPR000108 Neutrophil cytosol factor 2 2.26888
IPR011992 EF-Hand_type. IPR000108 Neutrophil cytosol factor 2 2.01056
IPR000449 Ubiquitin-associated domain IPR000980 SH2 motif 0.609113
IPR000449 Ubiquitin-associated domain IPR001452 SH3 0.223539
IPR000217 Tubulin IPR001452 SH3 0.17131
IPR000217 Tubulin IPR000980 SH2 motif 0.0425012

The background colour of the table refers to:

  • Blue Domain is only present in CBL
  • Yellow Domain is only present in GRB2
  • Green Domain is present in both CBL and GRB2

 0.109
Post-translational Modifications

Protein: CBL

PTMResidueReference
Phosphorylation 371 PubMed, HPRD
Phosphorylation 619 PubMed, HPRD
Phosphorylation 623 PubMed, HPRD
Phosphorylation 639 PubMed, HPRD
Phosphorylation 642 PubMed, HPRD
Phosphorylation 667 PubMed, HPRD
Phosphorylation 669 PubMed, HPRD
Phosphorylation 674 PubMed, HPRD
Phosphorylation 675 PubMed, HPRD
Phosphorylation 700 PubMed, HPRD
Phosphorylation 731 PubMed, HPRD
Phosphorylation 774 PubMed, HPRD
Phosphoserine 669 HPRD
Phosphotyrosine 371 PubMed, HPRD
Phosphotyrosine 674 HPRD
Phosphotyrosine 700 HPRD
Phosphotyrosine 774 HPRD

Protein: GRB2

PTMResidueReference
Phosphorylation 160 PubMed, HPRD
Localisation

Protein: CBL

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD

Protein: GRB2

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between CBL and GRB2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CBL andGRB2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CBL has 1376 interactors and GRB2 has 1488 interactors of which there are 964 common interactors.

Common InteractorName of Common InteractorScore for CBL-Interactor (?)Score for GRB2-Interactor (?)
ZAP70 ZAP70: Uncharacterized protein ZAP70 277.00 1.17
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 214.00 0.878
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 173.00 0.878
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 137.00 422.00
SORBS3 SORBS3, SCAM1: Vinexin 43.20 0.148
NCK2 NCK2: Cytoplasmic protein NCK2 30.80 0.148
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 5.94 11.50
YWHAB YWHAB: 14-3-3 protein beta/alpha 4.41 0.025
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 2.47 0.025
GRAP GRAP: GRB2-related adapter protein 2.13 2.04
SHC2 N/A 1.29 1.29
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 1.20 1.30
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 1.13 1.30
LOC392481 N/A 1.07 1.07
SHC4 SHC-transforming protein 4 1.07 1.07
NEDD4L N/A 1.07 0.119
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 1.01 1.17
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.902 1.30
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.878 1.17
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.878 1.17
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.878 1.17
SYK SYK: Tyrosine-protein kinase SYK 0.808 1.17
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.731 1.30
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.731 1.30
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.655 1.17
LYN LYN: Tyrosine-protein kinase Lyn 0.655 1.17
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.655 1.17
CSK CSK: Tyrosine-protein kinase CSK 0.655 1.17
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.655 1.17
HCK N/A 0.655 1.17
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.655 1.17
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.644 1.30
BMX N/A 0.644 1.30
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.617 0.617
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.617 0.617
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.617 0.617
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.617 0.617
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.577 1.17
JAK1 0.577 1.17
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.577 1.17
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.577 1.17
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.577 1.17
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.577 1.17
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.553 0.553
FLT4 VEGFR3 long form 0.553 0.553
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.540 0.980
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.540 0.980
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.540 0.980
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.483 0.483
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.483 0.878
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.483 0.878
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.483 0.878
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.483 0.878
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.445 0.878
ALK ALK: ALK tyrosine kinase receptor precursor 0.445 0.483
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.445 0.878
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.445 0.878
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.445 0.878
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.403 0.980
MET MET: Hepatocyte growth factor receptor precursor 0.403 0.980
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.361 0.878
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.361 0.878
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.361 0.878
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.361 0.878
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.320 0.980
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.318 0.878
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.318 0.878
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.318 0.878
INSR INSR: Insulin receptor precursor 0.318 0.878
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.318 0.878
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.318 0.878
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.318 0.878
KIT KIT: Mast/stem cell growth factor receptor precursor 0.318 0.878
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.286 0.878
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.286 0.878
PRKAA1 N/A 0.251 0.165
TNK1 TNK1: Non-receptor tyrosine-protein kinase TNK1 0.237 0.237
DYRK3 N/A 0.225 0.148
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.217 0.265
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.191 0.165
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.191 0.165
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.191 0.165
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.171 0.148
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.171 0.148
MAPK15 N/A 0.165 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.165 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.165 0.165
MAPKAPK5 N/A 0.165 0.165
PPEF1 N/A 0.165 0.052
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.165 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.165 0.148
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.165 0.165
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.152 0.165
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.152 0.109
PLEK PLEK, P47: Pleckstrin 0.152 0.109
STAT2 STAT2: Signal transducer and activator of transcription 2 0.152 0.109
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.152 0.165
ROCK1 ROCK1: Rho-associated protein kinase 1 0.152 0.165
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.152 0.109
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.152 0.165
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.152 0.165
STK16 N/A 0.152 0.165
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.152 0.165
IRS1 IRS1: Insulin receptor substrate 1 0.152 0.165
SCML2 SCML2: Sex comb on midleg-like protein 2 0.152 0.109
STAM2 STAM2: Signal transducing adapter molecule 2 0.148 0.148
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.148 0.098
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.148
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.148 0.098
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.148 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.148
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.148 0.098
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.148 0.148
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.148 0.098
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.098
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.148 0.148
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.148 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.148 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.148
ELMO1 N/A 0.148 0.148
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.148 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.148 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.148 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.148 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.148 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.148 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.148 0.148
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.148 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.148 0.098
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.148 0.098
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.148
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.145 0.237
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.143 0.265
FYN N/A 0.143 0.265
FGFR2 N/A 0.141 0.217
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.140 0.030
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.140 0.075
CDK7 CDK7, MO15: Cell division protein kinase 7 0.136 0.148
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.136 0.044
SOS1 SOS1: Son of sevenless homolog 1 0.136 18.00
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.136 0.098
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.136 0.148
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.136 0.148
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.136 0.148
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.136 0.148
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.136 0.148
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.136 0.148
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.136 0.148
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.136 0.148
TTN N/A 0.136 0.148
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.136 0.148
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.136 0.148
WEE1 WEE1: Wee1-like protein kinase 0.136 0.148
RYK RYK, JTK5A: Tyrosine-protein kinase RYK precursor 0.129 0.217
GRLF1 N/A 0.127 0.083
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.126 0.195
RPL11 RPL11: 60S ribosomal protein L11 0.126 0.119
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.123 0.165
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.123 0.165
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.123 0.165
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.123 0.109
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.123 0.028
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.123 0.165
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.123 0.165
DAPK2 DAPK2: Death-associated protein kinase 2 0.123 0.165
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.123 0.165
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.123 0.165
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.123 0.165
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.123 0.109
LTK LTK, TYK1: Leukocyte tyrosine kinase receptor precursor 0.116 0.195
INSRR INSRR, IRR: Insulin receptor-related protein precursor 0.116 0.195
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.111 0.148
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.111 0.148
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.111 0.148
CDK2 CDK2: Cell division protein kinase 2 0.111 0.148
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.111 0.148
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.111 0.148
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.111 0.148
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.111 0.148
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.111 0.148
CDK4 CDK4: Cell division protein kinase 4 0.111 0.148
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.111 0.148
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.111 0.148
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.111 0.148
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.111 0.075
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.111 0.148
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.111 0.148
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.111 0.148
CXorf9 N/A 0.111 0.148
CDK6 CDK6: Cell division protein kinase 6 0.111 0.148
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.111 0.148
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.111 0.098
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.111 0.148
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.111 0.098
ATM ATM: Serine-protein kinase ATM 0.111 0.148
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.111 0.148
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.111 0.148
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.111 0.148
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.111 0.148
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.111 0.148
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.111 0.148
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.111 0.148
FNBP1 N/A 0.111 4.22
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.111 0.148
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.111 0.148
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.111 0.148
DOK1 DOK1: Docking protein 1 0.111 0.148
STK10 STK10: Uncharacterized protein STK10 0.111 0.148
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.111 0.148
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.111 0.148
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.111 0.098
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.111 0.148
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.111 0.148
STAT4 STAT4: Signal transducer and activator of transcription 4 0.111 0.098
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.111 0.148
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.111 0.148
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.111 0.148
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.111 0.148
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.111 0.098
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.111 0.148
CASP8 CASP8, MCH5: Caspase-8 precursor 0.109 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.109 0.028
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
CASP9 CASP9, MCH6: Caspase-9 precursor 0.109 0.028
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
MAP2K5 N/A 0.109 0.165
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.109 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.165
PSCD2 N/A 0.109 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.109 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.109 0.165
CNN2 CNN2: Calponin-2 0.109 0.148
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.109 0.109
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.109 0.165
GAB1 GAB1: GRB2-associated-binding protein 1 0.109 0.165
IRS2 IRS2: Insulin receptor substrate 2 0.109 0.165
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.109 0.165
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.109 0.083
GAB2 N/A 0.109 0.165
TP73 TP73, P73: Tumor protein p73 0.109 0.109
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.109 0.165
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.165
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.109 0.109
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.109 0.165
CDKL5 N/A 0.109 0.165
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.109 0.165
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.109 0.109
ETS2 ETS2: Protein C-ets-2 0.109 0.109
AMHR2 AMHR2, AMHR: Anti-Muellerian hormone type-2 receptor precursor 0.105 0.217
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.100 0.165
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.100 0.165
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.098 0.109
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.098 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.098 0.025
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.098 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.148
ARHGEF7 N/A 0.098 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.098 0.148
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.047
STAT3 0.098 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.098 0.075
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.098 0.148
MYO18A 0.098 0.025
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.097 27.40
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.097 0.098
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.097 0.025
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.097 0.098
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.097 0.098
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.097 0.148
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.097 0.098
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.097 0.148
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.097 0.148
DAB1 DAB1: Disabled homolog 1 0.097 0.148
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.097 0.098
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.097 0.098
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.097 0.148
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.097 0.148
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.097 0.148
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.148
RPS6KB1 N/A 0.097 0.148
CDK5 CDK5: Cell division protein kinase 5 0.097 0.148
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.097 0.148
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.097 0.148
MYO3A MYO3A: Myosin IIIA 0.097 0.148
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.097 0.148
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.097 18.00
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.097 0.148
RIN1 RIN1: Ras and Rab interactor 1 0.097 0.148
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.148
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.097 0.148
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.097 0.148
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.097 0.148
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.097 0.148
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.097 0.148
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.097 0.148
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.097 0.148
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.097 0.148
ROR2 ROR2, NTRKR2: Tyrosine-protein kinase transmembrane receptor ROR2 precursor 0.094 0.195
MUSK MUSK: Muscle, skeletal receptor tyrosine protein kinase precursor 0.094 0.195
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.0924 0.217
STYK1 STYK1, NOK: Tyrosine protein-kinase STYK1 0.0924 0.217
RET urf-ret: Urf-ret protein 0.0924 0.217
TYRO3 TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor 0.0924 0.217
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.090 0.025
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.090 0.025
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.090 0.148
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.090 0.025
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.090 0.148
CD2AP CD2AP: CD2-associated protein 0.090 0.148
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.090 0.148
PSCD4 PSCD4, CYT4: Cytohesin-4 0.090 0.148
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.090 0.148
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.090 0.148
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.090 0.148
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.090 0.148
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.088 0.148
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.088 0.098
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.088 0.148
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.088 0.148
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.088 0.148
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.088 0.148
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.088 0.098
HES6 HES6: Transcription cofactor HES-6 0.083 0.049
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.083
MCF2 MCF2, DBL: Proto-oncogene DBL 0.081 0.165
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.081 0.028
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.165
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.165
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.081 0.165
LIMK2 LIMK2: LIM domain kinase 2 0.081 0.165
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.081 0.165
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.081 0.165
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.081 0.028
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.081 0.083
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.081 0.028
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.081 0.165
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.077 0.028
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.075 0.025
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.075 0.195
THOC1 THOC1, HPR1: THO complex subunit 1 0.073 0.025
RASA3 RASA3: Ras GTPase-activating protein 3 0.073 0.148
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.073 0.025
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.073 7.88
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.073 0.075
LCP1 LCP1, PLS2: Plastin-2 0.073 0.047
WASPIP N/A 0.073 7.88
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.073 0.025
STAT6 STAT6: Signal transducer and activator of transcription 6 0.073 0.148
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.073 7.88
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.073 0.148
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.073 0.148
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.073 0.148
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.073 0.075
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.073 0.148
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.073 0.148
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.073 0.148
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.073 0.148
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.073 0.025
VAV1 VAV1, VAV: Proto-oncogene vav 0.073 0.148
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.073 0.025
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.073 0.148
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.073 0.148
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.073 0.148
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.073 7.88
APS SH2B2, APS: SH2B adapter protein 2 0.073 0.148
PLD1 PLD1: Phospholipase D1 0.073 0.148
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.073 0.075
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.165
SPTAN1 N/A 0.072 0.165
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.072 0.165
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.072 0.165
FLNA FLNA, FLN, FLN1: Filamin-A 0.072 0.028
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.072 0.165
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.072 0.028
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.165
VASP VASP: Vasodilator-stimulated phosphoprotein 0.072 0.165
GAS2 GAS2: Growth arrest-specific protein 2 0.072 0.028
RYR1 0.071 0.030
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.071 0.062
LIG4 LIG4: DNA ligase 4 0.069 0.036
BRPF1 BRPF1, BR140: Peregrin 0.069 0.075
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.0688 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.0688 0.098
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.0688 0.098
KIR3DL1 N/A 0.0688 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.0688 0.109
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.0688 0.0688
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.0688 0.0688
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.0688 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.0688 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.0688 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.0688 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.0688 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.0688 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.0688 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.0688 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.0688 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.0688 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.0688 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.0688 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.0688 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.0688 0.109
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.0688 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.0688 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.0688 0.109
FN1 N/A 0.0688 0.109
CTTN CTTN, EMS1: Src substrate cortactin 0.065 4.22
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.065 0.028
COBL N/A 0.065 0.165
CNN3 CNN3: Calponin-3 0.065 0.148
PLD2 PLD2: Phospholipase D2 0.064 0.148
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.064 0.148
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.064 0.148
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.064 0.148
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.064 0.148
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.047
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.064 0.148
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.064 0.148
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.064 0.148
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.064 0.148
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.064 0.148
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.064 0.025
PARVA PARVA, MXRA2: Alpha-parvin 0.064 0.025
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.064 0.148
CRKL CRKL: Crk-like protein 0.064 0.148
VIL2 N/A 0.064 0.148
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.064 0.025
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.064 0.148
RDX RDX: Radixin 0.064 0.148
TLN1 TLN1: Uncharacterized protein TLN1 0.064 0.148
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.064 0.148
TLN2 TLN2: Uncharacterized protein TLN2 0.064 0.148
MSN MSN: Moesin 0.064 0.148
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.064 0.148
RPS10 RPS10: 40S ribosomal protein S10 0.064 0.025
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.064 0.148
CCR5 CCR5: CCR5 receptor (Fragment) 0.063 0.109
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.063 0.109
LILRB1 N/A 0.063 0.109
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.063 0.109
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.063 0.109
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.063 0.109
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.063 0.109
PRLR PRLR: Prolactin receptor precursor 0.063 0.109
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.063 0.109
ANXA9 ANXA9, ANX31: Annexin A9 0.063 0.04
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.063 0.109
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.063 0.109
IRF3 IRF3: Interferon regulatory factor 3 0.062 0.049
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.062 0.028
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.062 0.098
CNTN1 CNTN1: Contactin-1 precursor 0.062 0.098
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.062 0.098
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.062 0.062
KCNQ2 KCNQ2: Potassium voltage-gated channel subfamily KQT member 2 0.062 0.030
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.062 0.098
BSG N/A 0.062 0.098
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.062 0.098
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.062 0.044
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.062 0.098
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.062 0.098
CNTN4 CNTN4: Contactin-4 precursor 0.062 0.098
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.062 0.098
KCNH2 KCNH2, ERG, ERG1, HERG, HERG1: Potassium voltage-gated channel subfamily H membe 0.062 0.030
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.058 0.148
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.058 0.148
PSD TYL: TYL protein 0.058 0.148
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.058 0.148
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.058 0.148
NEO1 NEO1, NGN: Neogenin precursor 0.057 0.098
DCC DCC: Netrin receptor DCC precursor 0.057 0.098
MEP1B MEP1B: Meprin A subunit beta precursor 0.057 0.044
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.057 0.098
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.057 0.028
GRK7 GRK7, GPRK7: G protein-coupled receptor kinase 7 precursor 0.056 0.056
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.056 0.056
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.056 0.075
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.056 0.044
AIP AIP, XAP2: AH receptor-interacting protein 0.056 0.025
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.056 0.044
FKBP4 FKBP4: FK506-binding protein 4 0.056 0.025
HES1 HES1, HL, HRY: Transcription factor HES-1 0.056 0.044
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.056 0.098
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.056 0.025
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.056 0.025
SALL1 SALL1, SAL1: Sal-like protein 1 0.056 0.025
RELA RELA, NFKB3: Transcription factor p65 0.056 1.01
PHF10 N/A 0.056 0.044
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.055 0.028
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.055 0.028
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.053 0.046
SYTL4 Endocrine transmitter regulatory protein 0.052 0.049
FBXO4 FBXO4, FBX4: F-box only protein 4 0.052 0.028
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
PTPRA N/A 0.051 0.051
MAPK7 MAPK7, ERK4, ERK5, PRKM7: Mitogen-activated protein kinase 7 0.051 0.046
IGHD N/A 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NCAM1 N/A 0.051 0.051
GSK3B GSK3B: Glycogen synthase kinase-3 beta 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
PRKCD PRKCD: Protein kinase C delta type 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
C9orf88 N/A 0.051 0.051
MAP4K4 N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
HLA-A N/A 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
UBAP2L N/A 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
GRB10 N/A 0.051 0.051
CHUK CHUK, IKKA, TCF16: Inhibitor of nuclear factor kappa-B kinase subunit alpha 0.051 0.051
MAPK11 MAPK11, PRKM11, SAPK2: Mitogen-activated protein kinase 11 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
RAPH1 N/A 0.051 0.051
CDC42EP1 CDC42EP1, BORG5, CEP1, MSE55: Cdc42 effector protein 1 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
IGHG3 N/A 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
IGHM N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
IGHA1 N/A 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
MARK2 N/A 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
GPA33 GPA33: Cell surface A33 antigen precursor 0.051 0.109
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.051 0.109
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.051 0.0688
IL9R IL9R: Interleukin-9 receptor precursor 0.051 0.109
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.051 0.109
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.051 0.109
GHR GHR: Growth hormone receptor precursor 0.051 0.109
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.051 0.109
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.051 0.109
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.051 0.109
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.051 0.109
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.051 0.109
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.051 0.109
PVR PVR, PVS: Poliovirus receptor precursor 0.051 0.109
ITGB4 N/A 0.051 0.109
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.051 0.109
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.051 0.109
SORL1 SORL1: Sortilin-related receptor precursor 0.051 0.098
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.051 0.109
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.051 0.109
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.051 0.109
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.051 0.109
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.051 0.109
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.051 0.109
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.051 0.109
CSPG2 N/A 0.051 0.0688
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.051 0.109
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.051 0.0688
EPOR EPOR: Erythropoietin receptor precursor 0.051 0.109
EGF EGF: Pro-epidermal growth factor precursor 0.051 0.109
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.051 0.109
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.051 0.109
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.051 0.109
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.051 0.109
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.051 0.0688
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.051 0.109
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.051 0.109
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.051 0.109
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.051 0.109
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.051 0.109
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.051 0.109
ANXA3 ANXA3, ANX3: Annexin A3 0.051 0.04
F3 F3: Tissue factor precursor 0.051 0.109
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.051 0.109
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.051 0.025
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.051 0.075
RAB11FIP5 RAB11FIP5, GAF1, KIAA0857, RIP11: Rab11 family-interacting protein 5 0.051 0.025
FLII FLII, FLIL: Protein flightless-1 homolog 0.051 0.047
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.051 0.025
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.050
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.052
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.049 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.049 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.049 0.028
AXIN1 0.049 0.028
CASP14 CASP14: Caspase-14 precursor 0.049 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.049 0.083
YWHAG YWHAG: 14-3-3 protein gamma 0.049 0.028
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.049 0.083
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.052
WWC1 WWC1, KIAA0869: WW domain-containing protein 1 0.049 0.025
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.049 0.044
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.049 0.025
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.047 0.051
GIT2 N/A 0.047 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.047 0.036
SRPK1 SRPK1: Serine/threonine-protein kinase SRPK1 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
LMO7 N/A 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
TLK2 TLK2: Serine/threonine-protein kinase tousled-like 2 0.046 0.046
IKBKE IKBKE, IKKE, IKKI, KIAA0151: Inhibitor of nuclear factor kappa-B kinase subunit 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
SLC9A7 SLC9A7, NHE7: Sodium/hydrogen exchanger 7 0.046 0.044
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.046 0.062
DLG2 DLG2: Disks large homolog 2 0.046 0.062
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.046 0.098
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.046 0.098
SLC9A3 SLC9A3, NHE3: Sodium/hydrogen exchanger 3 0.046 0.044
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.046 0.062
KCNB1 KCNB1: Potassium voltage-gated channel subfamily B member 1 0.046 0.030
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.046 0.098
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.046 0.098
AKAP1 AKAP1, AKAP149, PRKA1: A kinase anchor protein 1, mitochondrial precursor 0.046 0.030
PRPH PRPH, NEF4, PRPH1: Peripherin 0.0453 0.028
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.0453 0.028
FHL1 FHL1, SLIM1: Four and a half LIM domains protein 1 0.0453 0.028
CRLF3 N/A 0.045 0.109
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.045 0.109
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.045 0.0688
SLC9A1 SLC9A1, APNH1, NHE1: Sodium/hydrogen exchanger 1 0.045 0.049
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.045 0.109
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.045 0.04
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.045 0.109
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.045 0.0688
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.045 0.109
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.045 0.0688
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.045 0.109
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.045 0.109
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.045 0.109
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.045 0.0688
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.045 0.109
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.045 0.0688
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.045 0.109
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.045 0.109
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.045 0.109
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.045 0.0688
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.045 0.109
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.045 0.04
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.045 0.109
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.045 0.0688
CD7 CD7: T-cell antigen CD7 precursor 0.045 0.109
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.045 0.109
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.045 0.109
RYR2 RYR2: Ryanodine receptor 2 0.045 0.034
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.045 0.109
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.045 0.109
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.044 0.025
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.044 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.044 0.148
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.044 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.044 0.025
LMO6 LMO6: LIM domain only protein 6 0.044 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.044 0.025
DCTN1 DCTN1: Dynactin subunit 1 0.044 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.025
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.043 0.025
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.042 0.046
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.041 0.109
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.0688
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.041 0.0688
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.041 0.109
LPXN LPXN, LDLP: Leupaxin 0.041 0.025
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.041 0.075
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.041 8.68
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.041 0.025
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.041 0.025
CDKN3 CDKN3, CDI1, CIP2, KAP: Cyclin-dependent kinase inhibitor 3 0.041 0.027
VRK3 N/A 0.041 0.027
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.041 0.098
ADCY3 ADCY3, KIAA0511: Adenylate cyclase type 3 0.041 0.044
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.041 0.098
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.041 0.098
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.041 0.062
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.041 0.062
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.062
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.041 0.098
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.041 0.062
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.041 0.098
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.041 0.098
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.041 0.098
MCOLN1 MCOLN1, ML4, MSTP080: Mucolipin-1 0.041 0.062
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.041 0.098
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.041 0.062
KCNA2 KCNA2: Potassium voltage-gated channel subfamily A member 2 0.041 0.030
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.041 0.062
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.028
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.039 0.049
CDC42EP3 CDC42EP3, BORG2, CEP3: Cdc42 effector protein 3 0.038 0.051
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.038 0.051
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.038 0.051
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.037 0.050
RAB32 RAB32: Ras-related protein Rab-32 0.037 0.050
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.037 0.028
FUBP1 N/A 0.037 0.083
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.037 0.028
CIITA CIITA, MHC2TA: MHC class II transactivator 0.037 0.028
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.037 0.028
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.037 0.028
S100A3 S100A3, S100E: Protein S100-A3 0.037 0.052
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.052
PTPRZ1 N/A 0.037 0.098
MEP1A MEP1A: Meprin A subunit alpha precursor 0.037 0.044
TNC TNC, HXB: Tenascin precursor 0.037 0.098
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.037 0.062
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.037 0.098
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.036 0.047
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.036 0.047
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.036 0.047
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.035 0.047
TSHR N/A 0.035 0.044
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.034 0.046
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.034 0.046
TNN TNN: Tenascin-N precursor 0.034 0.046
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.0338 0.051
CNN1 CNN1: Calponin-1 0.0338 0.046
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0338 0.051
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.034 0.049
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.034 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.034 0.049
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.034 0.049
MAL2 MAL2: Protein MAL2 0.034 0.034
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.034 0.049
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.034 0.109
DNASE1 DNASE1, DNL1, DRNI: Deoxyribonuclease-1 precursor 0.034 0.0688
WWC2 WW and C2 domain containing 2 0.033 0.025
TBCE TBCE: Tubulin-specific chaperone E 0.033 0.025
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.075
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.033 0.075
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.033 0.025
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.033 0.075
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.033 0.075
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.033 0.075
NOS1 NOS1: Nitric-oxide synthase, brain 0.033 0.025
EEF2 EEF2, EF2: Elongation factor 2 0.033 0.025
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.033 0.075
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.033 0.075
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.033 0.075
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.033 0.025
VCP VCP: Transitional endoplasmic reticulum ATPase 0.033 0.025
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.033 0.025
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.033 0.025
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.033 0.025
GMIP GMIP: GEM-interacting protein 0.033 0.075
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.033 0.025
RGS4 RGS4: Regulator of G-protein signaling 4 0.032 0.028
YWHAQ YWHAQ: 14-3-3 protein theta 0.032 0.028
LPP LPP: Lipoma-preferred partner 0.032 0.028
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.028
LIMS1 N/A 0.032 0.028
ZYX ZYX: Zyxin 0.032 0.028
S100A7 S100A7, PSOR1: Protein S100-A7 0.032 0.052
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.052
RGS16 RGS16, RGSR: Regulator of G-protein signaling 16 0.032 0.028
DES DES: Desmin 0.032 0.028
IPO4 N/A 0.032 0.027
OCLN OCLN: Occludin 0.031 0.034
NUAK1 NUAK1, ARK5, KIAA0537: NUAK family SNF1-like kinase 1 0.030 0.046
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.030 0.036
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.044
ATRN N/A 0.030 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.030 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.030 0.044
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.030 0.044
PHB2 PHB2, BAP, REA: Prohibitin-2 0.030 0.083
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.030 0.052
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.030 0.083
MVP MVP, LRP: Major vault protein 0.030 0.028
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.029 0.028
S100B S100B: Protein S100-B 0.029 0.052
GFAP GFAP: Glial fibrillary acidic protein 0.029 0.028
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.029 0.028
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.029 0.028
CRIP2 CRIP2, CRP2: Cysteine-rich protein 2 0.029 0.028
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.029 0.056
ACTG1 ACTB: Actin, cytoplasmic 1 0.029 0.075
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.029 0.148
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.025
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.029 0.075
YWHAE YWHAE: 14-3-3 protein epsilon 0.029 0.025
EEF1A2 EEF1A2, EEF1AL, STN: Elongation factor 1-alpha 2 0.029 0.025
PARD3 N/A 0.029 0.025
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.029 0.025
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.029 0.025
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.029 0.075
LIMA1 LIMA1, EPLIN, PP624, SREBP3: LIM domain and actin-binding protein 1 0.029 0.025
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.029 0.025
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.029 0.025
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.047
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.029 0.714
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.029 0.075
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.029 0.025
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.029 6.39
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.029 0.025
GSK3B N/A 0.029 0.025
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
ROS1 ROS1: Proto-oncogene tyrosine-protein kinase ROS precursor 0.0288 0.0288
NULL N/A 0.0288 0.0288
MUSK MUSK: MUSK protein 0.0288 0.0288
NULL Tyrosine kinase 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
TTN TTN: Uncharacterized protein TTN (Fragment) 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
TESK2 TESK2: Dual specificity testis-specific protein kinase 2 0.0288 0.0288
NTRK3 NTRK3, TRKC: NT-3 growth factor receptor precursor 0.0288 0.0288
NTRK3 N/A 0.0288 0.0288
NULL N/A 0.0288 0.0288
DDR2 DDR2, NTRKR3, TKT, TYRO10: Discoidin domain-containing receptor 2 precursor 0.0288 0.0288
AATK apoptosis-associated tyrosine kinase 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
PHLDB2 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
HPN HPN, TMPRSS1: Serine protease hepsin 0.028 0.044
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.028 0.098
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.027 0.025
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.027 0.025
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.027 0.025
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.027 0.025
EXOC2 N/A 0.027 0.025
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.027 0.047
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.027 0.047
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.027 0.025
ASB3 ASB3: ASB3 protein 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
NEK4 NEK4, STK2: Serine/threonine-protein kinase Nek4 0.027 0.027
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
FAM43A N/A 0.027 0.027
CDC2L2 N/A 0.027 0.027
SHANK1 SHANK1: SH3 and multiple ankyrin repeat domains protein 1 0.027 0.027
TRIM9 TRIM9, KIAA0282, RNF91: Tripartite motif-containing protein 9 0.027 0.027
OSBPL9 N/A 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
MID2 N/A 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
ALS2CR7 ALS2CR7: Serine/threonine-protein kinase ALS2CR7 0.027 0.027
FANK1 FANK1, HSD13, UNQ6504/PRO21382: Fibronectin type 3 and ankyrin repeat domains pr 0.027 0.027
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
CASKIN1 N/A 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
RIPK5 RIPK5, KIAA0472, HDCMD38P, RIP5, SGK496: Receptor-interacting serine/threonine-p 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
CAMKK1 CAMKK1, CAMKKA: Calcium/calmodulin-dependent protein kinase kinase 1 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
STK35 STK35, CLIK1, PDIK1: Serine/threonine-protein kinase 35 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
NEK11 NEK11: Serine/threonine-protein kinase Nek11 0.027 0.027
PPP1R9A PPP1R9A, KIAA1222: Neurabin-1 0.027 0.027
UBL7 UBL7, BMSCUBP, SB132: Ubiquitin-like protein 7 0.027 0.027
PDIK1L PDIK1L, CLIK1L: Serine/threonine-protein kinase PDIK1L 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.0263 0.052
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.0263 0.052
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.0263 0.052
MT3 MT3: Metallothionein-3 0.026 0.056
PPP2CB PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.026 0.025
PMP2 PMP2: Myelin P2 protein 0.026 0.075
MAGED2 N/A 0.026 0.025
FES N/A 0.0258 0.0258
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.026 0.028
ESPL1 N/A 0.026 0.028
KIF23 N/A 0.026 0.049
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.028
UBAP2 N/A 0.026 0.028
TRRAP N/A 0.026 0.028
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.025 0.109
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.025 0.049
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.025 0.049
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.025 0.04
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.025 0.109
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.025 0.049
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.047
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.075
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.075
PRKCB1 N/A 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.098
BCOR N/A 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
CAMK2A N/A 0.025 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.366
NIPBL N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
GRK6 N/A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
0.572
Total Score 1.91E3