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Evidence of Interaction Between LSM2 and LSM5

The interaction score between LSM2 and LSM5 is 2.94E5.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between LSM2 and LSM5 = 0.71

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 0.013
Orthology
OrganismLSM2 OrthologueLSM5 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YBL026W 1 YER146W 1
  • Y2H
  • Other

Get References From PubMed
worm P92022 1 O18694 1
fly Q9VTW6 1 Q9VRT7 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.593
Domains Domains present in LSM2 and LSM5:
Domains in LSM2Domains in LSM5
IPR001163 Small nuclear ribonucleoprotein (Sm protein)
IPR006649 snRNP domain
IPR001163 Small nuclear ribonucleoprotein (Sm protein)
IPR006649 snRNP domain

The Chi square scores for co-occurrence of domains that are present in LSM2 and LSM5 are listed below.

Domain 1Domain 2Chi Square
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR006649 snRNP domain 1325.87
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR001163 Small nuclear ribonucleoprotein (Sm protein) 1297.61
IPR006649 snRNP domain IPR006649 snRNP domain 1206.57

The background colour of the table refers to:

  • Blue Domain is only present in LSM2
  • Yellow Domain is only present in LSM5
  • Green Domain is present in both LSM2 and LSM5

 1.05
Post-translational Modifications

Protein: LSM2

PTMResidueReference
Phosphotyrosine 35 HPRD

Protein: LSM5

PTMResidueReference
N-acetylalanine 1 HPRD
Localisation

Protein: LSM2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: LSM5

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between LSM2 and LSM5 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between LSM2 andLSM5. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , LSM2 has 894 interactors and LSM5 has 349 interactors of which there are 285 common interactors.

Common InteractorName of Common InteractorScore for LSM2-Interactor (?)Score for LSM5-Interactor (?)
LSM7 LSM7: U6 snRNA-associated Sm-like protein LSm7 3.51E3 3.51E3
SNRPD2 SNRPD2, SNRPD1: Small nuclear ribonucleoprotein Sm D2 1.64E3 3.51E3
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 1.59E3 38.60
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 1.59E3 3.41E3
LSM3 LSM3, MDS017: U6 snRNA-associated Sm-like protein LSm3 778.00 2.74E3
LSM4 LSM4: U6 snRNA-associated Sm-like protein LSm4 691.00 323.00
LSM1 LSM1, CASM: U6 snRNA-associated Sm-like protein LSm1 592.00 195.00
LSM8 LSM8: U6 snRNA-associated Sm-like protein LSm8 383.00 4.86
LSM6 LSM6: U6 snRNA-associated Sm-like protein LSm6 323.00 1.64E3
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 122.00 68.20
PRPF4 PRPF4, PRP4: U4/U6 small nuclear ribonucleoprotein Prp4 32.60 32.60
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 20.60 0.078
PRP19 PRPF19, NMP200, PRP19, SNEV: Pre-mRNA-processing factor 19 15.50 0.0968
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 9.09 0.093
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 4.09 4.09
PRPF8 PRPF8, PRPC8: Pre-mRNA-processing-splicing factor 8 3.05 1.49
SNRPB SNRPB, COD, SNRPB1: Small nuclear ribonucleoprotein-associated proteins B and B' 2.91 2.91
LOC119358 similar to small nuclear ribonucleoprotein D2 1.79 0.071
SNRPE SNRPE: Small nuclear ribonucleoprotein E 1.36 8.73
SNRPF SNRPF, PBSCF: Small nuclear ribonucleoprotein F 1.22 205.00
SNRPG SNRPG, PBSCG: Small nuclear ribonucleoprotein G 1.22 691.00
DCP1A DCP1A, SMIF: mRNA-decapping enzyme 1A 1.20 0.918
FLJ36874 N/A 1.15 0.218
PRPF6 PRPF6, C20orf14: Pre-mRNA-processing factor 6 1.10 0.890
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.852 0.287
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.763 0.257
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.704 1.50
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.683 0.160
AGL AGL: Uncharacterized protein AGL (Fragment) 0.593 0.593
GNB2L1 Lung cancer oncogene 7 0.515 0.287
DDX21 DDX21: Nucleolar RNA helicase 2 0.515 0.613
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.461 0.126
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.461 0.257
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.461 0.156
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.461 0.156
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.461 0.257
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.461 0.156
CDC20 CDC20: Cell division cycle protein 20 homolog 0.461 0.156
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.461 0.257
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.461 0.156
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.416 0.287
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.372 0.156
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.372 0.156
XRN1 XRN1, SEP1: 5'-3' exoribonuclease 1 0.354 0.354
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.307 0.025
WDR1 N/A 0.307 0.103
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.287 0.287
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.276 0.129
MCM3 MCM3: DNA replication licensing factor MCM3 0.276 0.048
COPA COPA: Coatomer subunit alpha 0.275 0.093
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.275 0.093
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.275 0.093
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.275 0.156
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.275 0.126
BOP1 BOP1, KIAA0124: Ribosome biogenesis protein BOP1 0.263 0.123
POLD1 POLD1, POLD: DNA polymerase delta catalytic subunit 0.263 0.123
WDR77 WDR77, HKMT1069, hCG_39991: Androgen receptor cofactor p44 0.263 0.123
RBBP4 RBBP4, RBAP48: Histone-binding protein RBBP4 0.257 0.257
Nle NLE1, HUSSY-07: Notchless protein homolog 1 0.257 0.126
LSM10 LSM10: U7 snRNA-associated Sm-like protein LSm10 0.237 0.237
LSM11 LSM11: U7 snRNA-associated Sm-like protein LSm11 0.237 0.237
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.225 0.156
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.225 0.093
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.225 0.076
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.225 0.156
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.225 0.156
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.225 0.126
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.225 0.093
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.225 0.058
CORO1C CORO1C, CRNN4: Coronin-1C 0.225 0.126
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.171 0.126
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.171 0.046
WDR54 N/A 0.165 0.056
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.165 0.056
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.156 0.257
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.152
NUP214 N/A 0.152 0.051
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.148 0.050
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.148 0.050
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.148 0.050
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.148 0.050
CETN1 CETN1, CEN1, CETN: Centrin-1 0.148 0.050
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.148 0.050
GEMIN5 GEMIN5: Gem-associated protein 5 0.148 0.050
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.148 0.050
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.148 0.050
MKI67 MKI67: Antigen KI-67 0.144 0.025
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.144 0.025
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.144 0.054
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.144 0.054
SET SET: Protein SET 0.144 0.054
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.144 0.054
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.025
DNMT1 DNMT1, AIM, DNMT: DNA 0.144 0.025
SNRPN HCERN3, SNRPN, SMN: Small nuclear ribonucleoprotein-associated protein N 0.141 0.158
GTF3C2 GTF3C2, KIAA0011: General transcription factor 3C polypeptide 2 0.137 0.137
DHX15 DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase 0.137 0.293
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.137
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.137
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.136 0.058
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.136 0.058
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.048
NPM1 NPM1, NPM: Nucleophosmin 0.129 0.048
TP53 TP53, P53: Cellular tumor antigen p53 0.129 0.129
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.129 0.048
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.129 0.048
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.129 0.048
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.129 0.048
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.129 0.048
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.129 0.048
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.129 0.129
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.129 0.048
PCNA PCNA: Proliferating cell nuclear antigen 0.129 0.276
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.129 0.048
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.129 0.048
WDR57 WDR57, PRP8BP, SFP38: WD repeat-containing protein 57 0.123 0.074
DDX39 DDX39: ATP-dependent RNA helicase DDX39 0.123 0.074
NUP37 NUP37: Nucleoporin Nup37 0.123 0.263
FLJ10439 WDR74, NSA1: WD repeat-containing protein 74 0.123 0.123
HELLS HELLS, PASG, Nbla10143, SMARCA6: Lymphoid-specific helicase 0.123 0.074
NULL Putative uncharacterized protein (Fragment) 0.119 0.119
LOC197135 N/A 0.119 0.119
SMARCA1 SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1 0.099 0.033
NUTF2 NUTF2, NTF2: Nuclear transport factor 2 0.0968 0.059
COPB2 COPB2: Coatomer subunit beta' 0.093 0.126
SEC31L1 N/A 0.093 0.126
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.093 0.093
PTMA N/A 0.087 0.054
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.087 0.054
NBN NBN, NBS, NBS1, P95: Nibrin 0.087 0.025
RB1 RB1: Retinoblastoma-associated protein 0.087 0.025
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.087 0.025
SEC13L1 SEC13, D3S1231E, SEC13L1, SEC13R: Protein SEC13 homolog 0.083 0.083
WDR41 N/A 0.083 0.137
DDB2 DDB2: DNA damage-binding protein 2 0.083 0.083
ATP9A ATP9A, ATPIIA, KIAA0611: Probable phospholipid-transporting ATPase IIA 0.080 0.080
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.078 0.063
H2AFX H2AFX, H2AX: Histone H2A.x 0.078 0.078
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.078 0.048
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.078 0.129
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.078 0.048
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.078 0.048
CBX3 CBX3: Chromobox protein homolog 3 0.078 0.048
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.078 0.048
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.078 0.048
SSB SSB: Lupus La protein 0.078 0.048
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.078 0.048
NUP153 N/A 0.078 0.048
DDX47 E4-DBP: DEAD box protein 0.074 0.123
CNOT7 CNOT7, CAF1: CCR4-NOT transcription complex subunit 7 0.074 0.123
STRAP STRAP, MAWD, UNRIP: Serine-threonine kinase receptor-associated protein 0.074 0.123
PPP2R2A PPP2R2A: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alp 0.074 0.074
DDX28 DDX28, MDDX28: Probable ATP-dependent RNA helicase DDX28 0.074 0.060
PWP2H PWP2, PWP2H: Periodic tryptophan protein 2 homolog 0.074 0.074
RBBP7 RBBP7, RBAP46: Histone-binding protein RBBP7 0.074 0.123
ASCC3 ASCC3, HELIC1: Activating signal cointegrator 1 complex subunit 3 0.074 0.074
POLE POLE, POLE1: DNA polymerase epsilon catalytic subunit A 0.074 0.074
NUP43 N/A 0.074 0.263
DDX19A DDX19A, DDX19L: ATP-dependent RNA helicase DDX19A 0.074 0.074
EIF4A1 EIF4A1, DDX2A, EIF4A: Eukaryotic initiation factor 4A-I 0.074 0.263
RAD54L RAD54L, RAD54A: DNA repair and recombination protein RAD54-like 0.074 0.123
WDR12 WDR12: WD repeat-containing protein 12 0.074 0.123
DDX18 DDX18: ATP-dependent RNA helicase DDX18 0.074 0.123
RNU3IP2 RRP9, RNU3IP2, U355K: U3 small nucleolar RNA-interacting protein 2 0.074 0.060
WDR39 CIAO1, WDR39: Protein CIAO1 0.074 0.060
WDR18 N/A 0.074 0.123
DDX10 DDX10: Probable ATP-dependent RNA helicase DDX10 0.074 0.123
DDX54 DDX54: ATP-dependent RNA helicase DDX54 0.074 0.074
TSSC1 TSSC1: Protein TSSC1 0.074 0.074
DDX49 DDX49: Probable ATP-dependent RNA helicase DDX49 0.074 0.074
WDR68 WDR68, HAN11: WD repeat-containing protein 68 0.074 0.074
BAT1 N/A 0.074 0.123
DDX48 EIF4A3, DDX48, KIAA0111: Eukaryotic initiation factor 4A-III 0.074 0.074
ATP9B ATP9B, ATPIIB, HUSSY-20, NEO1L: Probable phospholipid-transporting ATPase IIB 0.074 0.060
RAD54B RAD54B: DNA repair and recombination protein RAD54B 0.067 0.067
FBXW2 FBXW2, FBW2, FWD2: F-box/WD repeat-containing protein 2 0.067 0.083
DDX50 DDX50: ATP-dependent RNA helicase DDX50 0.067 0.137
WDR8 WDR8: WD repeat-containing protein 8 0.067 0.067
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.066 0.033
CCT8 CCT8: Uncharacterized protein CCT8 0.066 0.033
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.066 0.033
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.066 0.033
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.066 0.033
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.066 0.033
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.063 0.048
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.063 0.048
HDAC2 HDAC2: Histone deacetylase 2 0.063 0.048
LRBA LRBA, BGL, CDC4L, LBA: Lipopolysaccharide-responsive and beige-like anchor prote 0.060 0.074
IFIH1 IFIH1, MDA5, RH116: Interferon-induced helicase C domain-containing protein 1 0.060 0.060
TAF5 TAF5, TAF2D: Transcription initiation factor TFIID subunit 5 0.060 0.123
KIAA0052 SKIV2L2, KIAA0052: Superkiller viralicidic activity 2-like 2 0.060 0.074
THRAP5 MED16, DRIP92, THRAP5: Mediator of RNA polymerase II transcription subunit 16 0.060 0.036
DDX23 DDX23: Probable ATP-dependent RNA helicase DDX23 0.060 0.074
XPMC2H REXO4, PMC2, XPMC2H: RNA exonuclease 4 0.060 0.074
WDR3 WDR3: WD repeat-containing protein 3 0.060 0.123
CDC40 CDC40, EHB3, PRP17, PRPF17: Pre-mRNA-processing factor 17 0.060 0.074
EML3 EML3: Echinoderm microtubule-associated protein-like 3 0.060 0.044
PARN PARN, DAN: Poly(A)-specific ribonuclease PARN 0.060 0.036
GRWD1 GRWD1, GRWD, WDR28: Glutamate-rich WD repeat-containing protein 1 0.060 0.060
AAMP AAMP: Angio-associated migratory cell protein 0.060 0.060
TTF2 TTF2: Transcription termination factor 2 0.060 0.074
DDX1 DDX1: ATP-dependent RNA helicase DDX1 0.060 0.263
DDX27 DDX27, RHLP, HSPC259, PP3241: Probable ATP-dependent RNA helicase DDX27 0.060 0.074
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.056 0.056
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.054 0.044
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.052 0.070
GNB4 GNB4: Guanine nucleotide-binding protein subunit beta-4 0.050 0.050
ISG20 ISG20, HEM45: Interferon-stimulated gene 20 kDa protein 0.050 0.041
SMARCAL1 SMARCAL1, HARP: SWI/SNF-related matrix-associated actin-dependent regulator of c 0.050 0.083
GNB1L GNB1L, GY2, FKSG1, KIAA1645, WDR14: Guanine nucleotide-binding protein subunit b 0.050 0.041
SNRPA SNRPA: U1 small nuclear ribonucleoprotein A 0.048 0.048
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.046 0.063
WIPI2 WIPI2, CGI-50: WD repeat domain phosphoinositide-interacting protein 2 0.044 0.060
DHX38 DHX38, DDX38, KIAA0224, PRP16: Pre-mRNA-splicing factor ATP-dependent RNA helica 0.044 0.060
DHX35 C20orf15, DHX35, DDX35: Probable ATP-dependent RNA helicase DHX35 0.044 0.060
DDX17 DDX17: Probable ATP-dependent RNA helicase DDX17 0.044 0.060
PIK3R4 PIK3R4: Phosphoinositide 3-kinase regulatory subunit 4 0.044 0.060
RECQL RECQL, RECQL1: ATP-dependent DNA helicase Q1 0.044 0.074
NBEAL2 N/A 0.044 0.044
ARPC1A ARPC1A, SOP2L: Actin-related protein 2/3 complex subunit 1A 0.044 0.044
CORO1A CORO1A, CORO1: Coronin-1A 0.044 0.044
POLA POLA1, POLA: DNA polymerase alpha catalytic subunit 0.044 0.060
AAAS AAAS, ADRACALA, GL003: Aladin 0.044 0.044
DDX56 DDX56, DDX21, NOH61: Probable ATP-dependent RNA helicase DDX56 0.044 0.036
CORO7 CORO7: Coronin-7 0.044 0.044
WDR13 WDR13: WD repeat-containing protein 13 0.041 0.0308
REV3L REV3L, POLZ, REV3: DNA polymerase zeta catalytic subunit 0.041 0.041
CDC23 CDC23: Cell division cycle protein 23 homolog 0.040 0.033
XPO1 XPO1, CRM1: Exportin-1 0.040 0.033
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.040 0.141
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.040 0.033
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.038 0.038
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.038 0.063
DYNC1I2 N/A 0.037 0.046
SH3BP3 0.037 0.051
LGP2 DHX58, D11LGP2E, LGP2: Probable ATP-dependent RNA helicase DHX58 0.036 0.036
WDR42A N/A 0.036 0.028
RAE1 RAE1, MRNP41: mRNA export factor 0.036 0.044
PEX7 PEX7, PTS2R: Peroxisomal targeting signal 2 receptor 0.036 0.028
WDR67 WDR67: WD repeat-containing protein 67 0.036 0.044
WDR45L N/A 0.036 0.036
SETDB1 SETDB1, KIAA0067: Histone-lysine N-methyltransferase SETDB1 0.036 0.036
CNOT8 CNOT8, CALIF, POP2: CCR4-NOT transcription complex subunit 8 0.036 0.060
JMJD2C JMJD2C, GASC1, JHDM3C, KIAA0780: JmjC domain-containing histone demethylation pr 0.036 0.060
RECQL4 RECQL4, RECQ4: ATP-dependent DNA helicase Q4 0.036 0.060
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.036 0.036
POLG POLG, MDP1, POLG1, POLGA: DNA polymerase subunit gamma-1 0.0331 0.0331
RNASEH1 RNASEH1, RNH1: Ribonuclease H1 0.0331 0.0331
TCP1 CCT1, CCTA, TCP1: T-complex protein 1 subunit alpha 0.033 0.033
PHF20 PHF20, C20orf104, GLEA2, HCA58, NZF, TZP: PHD finger protein 20 0.032 0.039
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.029 0.038
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.029 0.046
CREBBP CREBBP, CBP: CREB-binding protein 0.029 0.029
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.029 0.038
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
SNRPB N/A 0.028 0.028
DDX52 DDX52, ROK1, HUSSY-19: Probable ATP-dependent RNA helicase DDX52 0.028 0.044
WDR48 WDR48, KIAA1449: WD repeat-containing protein 48 0.028 0.028
WDR26 WDR26, CDW2, PRO0852, MIP2: WD repeat-containing protein 26 0.028 0.036
WDR37 N/A 0.028 0.028
LBR LBR: Lamin-B receptor 0.027 0.0331
WDR53 N/A 0.027 0.027
REXO1L1 REXO1L1, GOR: Exonuclease GOR 0.027 0.027
RFWD2 RFWD2, COP1, RNF200: E3 ubiquitin-protein ligase RFWD2 0.027 0.027
TDRD4 TDRD4: Tudor domain-containing protein 4 0.027 0.027
TLE6 TLE6: Transducin-like enhancer protein 6 0.027 0.027
BRWD1 N/A 0.027 0.027
FBXW8 FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6: F-box/WD repeat-containing protein 8 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
DDX53 DDX53, CAGE: Probable ATP-dependent RNA helicase DDX53 0.027 0.027
TAF5L TAF5L, PAF65B: TAF5-like RNA polymerase II p300/CBP-associated factor-associated 0.027 0.027
FLJ12671 ISG20L2, HSD38, HSD-38: Interferon-stimulated 20 kDa exonuclease-like 2 0.027 0.027
TREX1 TREX1: Three prime repair exonuclease 1 0.027 0.027
PHF1 N/A 0.027 0.027
WDR34 N/A 0.027 0.027
WDR17 N/A 0.027 0.027
WDR72 N/A 0.027 0.027
ERCC8 ERCC8, CKN1, CSA: DNA excision repair protein ERCC-8 0.027 0.027
KIF21A N/A 0.027 0.027
NEDD1 N/A 0.027 0.027
SNRPB N/A 0.0258 0.0258
SAT SAT1, SAT: Diamine acetyltransferase 1 0.026 0.032
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.025 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
0.572
Total Score 2.94E5