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Evidence of Interaction Between LSM3 and LSM2

The interaction score between LSM3 and LSM2 is 1.78E5.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between LSM3 and LSM2 = 0.65

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 7.78E-3
Orthology
OrganismLSM3 OrthologueLSM2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YLR438C-A 1 YBL026W 1
  • Y2H
  • Other

Get References From PubMed
worm Q9U1W8 1 P92022 1
fly Q8IMX8 1 Q9VTW6 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.593
Domains Domains present in LSM3 and LSM2:
Domains in LSM3Domains in LSM2
IPR001163 Small nuclear ribonucleoprotein (Sm protein)
IPR010920 Small nuclear-like ribonucleoprotein
IPR006649 snRNP domain
IPR001163 Small nuclear ribonucleoprotein (Sm protein)
IPR006649 snRNP domain

The Chi square scores for co-occurrence of domains that are present in LSM3 and LSM2 are listed below.

Domain 1Domain 2Chi Square
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR006649 snRNP domain 1325.87
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR001163 Small nuclear ribonucleoprotein (Sm protein) 1297.61
IPR006649 snRNP domain IPR006649 snRNP domain 1206.57
IPR010920 Small nuclear-like ribonucleoprotein IPR006649 snRNP domain 1168.89
IPR010920 Small nuclear-like ribonucleoprotein IPR001163 Small nuclear ribonucleoprotein (Sm protein) 1143.95

The background colour of the table refers to:

  • Blue Domain is only present in LSM3
  • Yellow Domain is only present in LSM2
  • Green Domain is present in both LSM3 and LSM2

 1.05
Post-translational Modifications

Protein: LSM3

PTMResidueReference
N-acetylalanine 1 HPRD

Protein: LSM2

PTMResidueReference
Phosphotyrosine 35 HPRD
Localisation

Protein: LSM3

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: LSM2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between LSM3 and LSM2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between LSM3 andLSM2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , LSM3 has 321 interactors and LSM2 has 894 interactors of which there are 276 common interactors.

Common InteractorName of Common InteractorScore for LSM3-Interactor (?)Score for LSM2-Interactor (?)
LSM5 LSM5: U6 snRNA-associated Sm-like protein LSm5 2.74E3 1.28E3
LSM7 LSM7: U6 snRNA-associated Sm-like protein LSm7 691.00 3.51E3
LSM4 LSM4: U6 snRNA-associated Sm-like protein LSm4 323.00 691.00
LSM6 LSM6: U6 snRNA-associated Sm-like protein LSm6 323.00 323.00
LSM1 LSM1, CASM: U6 snRNA-associated Sm-like protein LSm1 323.00 592.00
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 68.20 122.00
PRPF4 PRPF4, PRP4: U4/U6 small nuclear ribonucleoprotein Prp4 32.60 32.60
PRP19 PRPF19, NMP200, PRP19, SNEV: Pre-mRNA-processing factor 19 25.60 15.50
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 12.80 1.59E3
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 12.80 1.59E3
LSM8 LSM8: U6 snRNA-associated Sm-like protein LSm8 10.30 383.00
SNRPE SNRPE: Small nuclear ribonucleoprotein E 2.91 1.36
SNRPF SNRPF, PBSCF: Small nuclear ribonucleoprotein F 2.60 1.22
SNRPG SNRPG, PBSCG: Small nuclear ribonucleoprotein G 2.60 1.22
SNRPD2 SNRPD2, SNRPD1: Small nuclear ribonucleoprotein Sm D2 2.60 1.64E3
PRPF8 PRPF8, PRPC8: Pre-mRNA-processing-splicing factor 8 1.84 3.05
PRPF3 PRPF3, HPRP3, PRP3: U4/U6 small nuclear ribonucleoprotein Prp3 1.84 1.10
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 1.50 0.704
SNRPB SNRPB, COD, SNRPB1: Small nuclear ribonucleoprotein-associated proteins B and B' 1.36 2.91
DCP1A DCP1A, SMIF: mRNA-decapping enzyme 1A 1.20 1.20
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 1.16 0.025
PRPF31 PRPF31, PRP31: U4/U6 small nuclear ribonucleoprotein Prp31 1.10 1.10
PRPF6 PRPF6, C20orf14: Pre-mRNA-processing factor 6 0.890 1.10
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.427 0.908
SNRPEL1 RP11-390F4.1-001: Small nuclear ribonucleoprotein polypeptide E-like protein 1. 0.354 0.354
XRN1 XRN1, SEP1: 5'-3' exoribonuclease 1 0.354 0.354
DHX15 DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase 0.293 0.137
DDX50 DDX50: ATP-dependent RNA helicase DDX50 0.293 0.067
DDX21 DDX21: Nucleolar RNA helicase 2 0.287 0.515
GNB2L1 Lung cancer oncogene 7 0.287 0.515
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.287 0.416
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.287 0.287
CNOT7 CNOT7, CAF1: CCR4-NOT transcription complex subunit 7 0.263 0.074
DDX1 DDX1: ATP-dependent RNA helicase DDX1 0.263 0.060
NUP37 NUP37: Nucleoporin Nup37 0.263 0.123
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.257 0.461
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.257 0.763
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.257 0.461
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.257 0.461
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.257 0.461
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.257 0.156
RBBP4 RBBP4, RBAP48: Histone-binding protein RBBP4 0.257 0.257
DCP2 DCP2, NUDT20: mRNA-decapping enzyme 2 0.249 0.201
LSM11 LSM11: U7 snRNA-associated Sm-like protein LSm11 0.237 0.237
LSM10 LSM10: U7 snRNA-associated Sm-like protein LSm10 0.237 0.237
FLJ36874 N/A 0.218 1.15
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.174 0.852
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.160 0.683
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.156 0.275
CDC20 CDC20: Cell division cycle protein 20 homolog 0.156 0.461
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.156 0.461
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.156 0.275
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.156 0.372
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.156 0.461
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.156 0.461
SEC31L1 N/A 0.156 0.093
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.156 0.372
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.152
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.141 0.040
SNRPN HCERN3, SNRPN, SMN: Small nuclear ribonucleoprotein-associated protein N 0.141 0.141
WDR1 N/A 0.140 0.307
GTF3C2 GTF3C2, KIAA0011: General transcription factor 3C polypeptide 2 0.137 0.137
SMARCAL1 SMARCAL1, HARP: SWI/SNF-related matrix-associated actin-dependent regulator of c 0.137 0.050
WDR41 N/A 0.137 0.083
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.137
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.137
PCNA PCNA: Proliferating cell nuclear antigen 0.129 0.129
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.129 0.276
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.129 0.078
COPB2 COPB2: Coatomer subunit beta' 0.126 0.093
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.126 0.225
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.126 0.225
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.126 0.225
COPA COPA: Coatomer subunit alpha 0.126 0.275
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.126 0.225
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.126 0.171
DDX23 DDX23: Probable ATP-dependent RNA helicase DDX23 0.123 0.060
DDX18 DDX18: ATP-dependent RNA helicase DDX18 0.123 0.074
WDR3 WDR3: WD repeat-containing protein 3 0.123 0.060
DDX49 DDX49: Probable ATP-dependent RNA helicase DDX49 0.123 0.074
NUP43 N/A 0.123 0.074
DDX39 DDX39: ATP-dependent RNA helicase DDX39 0.123 0.123
EIF4A1 EIF4A1, DDX2A, EIF4A: Eukaryotic initiation factor 4A-I 0.123 0.074
PPP2R2A PPP2R2A: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alp 0.123 0.074
TAF5 TAF5, TAF2D: Transcription initiation factor TFIID subunit 5 0.123 0.060
DDX47 E4-DBP: DEAD box protein 0.123 0.074
WDR68 WDR68, HAN11: WD repeat-containing protein 68 0.123 0.074
RBBP7 RBBP7, RBAP46: Histone-binding protein RBBP7 0.123 0.074
BAT1 N/A 0.123 0.074
LOC645472 hCG_23490: Uncharacterized protein ENSP00000329276 0.119 0.119
LOC197135 N/A 0.119 0.119
NULL N/A 0.119 0.119
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.093 0.275
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.093 0.093
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.093 0.225
Nle NLE1, HUSSY-07: Notchless protein homolog 1 0.093 0.257
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.093 0.461
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.093 9.09
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.093 0.225
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.093 0.225
CORO1C CORO1C, CRNN4: Coronin-1C 0.093 0.225
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.093 0.275
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.093 0.225
SEC13L1 SEC13, D3S1231E, SEC13L1, SEC13R: Protein SEC13 homolog 0.083 0.083
FBXW2 FBXW2, FBW2, FWD2: F-box/WD repeat-containing protein 2 0.083 0.067
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.078 0.038
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 20.60
TP53 TP53, P53: Cellular tumor antigen p53 0.078 0.129
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.078 0.129
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.078 0.046
RECQL RECQL, RECQL1: ATP-dependent DNA helicase Q1 0.074 0.044
RAD54L RAD54L, RAD54A: DNA repair and recombination protein RAD54-like 0.074 0.074
STRAP STRAP, MAWD, UNRIP: Serine-threonine kinase receptor-associated protein 0.074 0.074
BOP1 BOP1, KIAA0124: Ribosome biogenesis protein BOP1 0.074 0.263
TSSC1 TSSC1: Protein TSSC1 0.074 0.074
ASCC3 ASCC3, HELIC1: Activating signal cointegrator 1 complex subunit 3 0.074 0.074
WDR18 N/A 0.074 0.074
WDR12 WDR12: WD repeat-containing protein 12 0.074 0.074
LRBA LRBA, BGL, CDC4L, LBA: Lipopolysaccharide-responsive and beige-like anchor prote 0.074 0.060
DDX27 DDX27, RHLP, HSPC259, PP3241: Probable ATP-dependent RNA helicase DDX27 0.074 0.060
DDX48 EIF4A3, DDX48, KIAA0111: Eukaryotic initiation factor 4A-III 0.074 0.074
FLJ10439 WDR74, NSA1: WD repeat-containing protein 74 0.074 0.123
DDX54 DDX54: ATP-dependent RNA helicase DDX54 0.074 0.074
CDC40 CDC40, EHB3, PRP17, PRPF17: Pre-mRNA-processing factor 17 0.074 0.060
POLD1 POLD1, POLD: DNA polymerase delta catalytic subunit 0.074 0.263
KIAA0052 SKIV2L2, KIAA0052: Superkiller viralicidic activity 2-like 2 0.074 0.060
JMJD2C JMJD2C, GASC1, JHDM3C, KIAA0780: JmjC domain-containing histone demethylation pr 0.074 0.036
POLE POLE, POLE1: DNA polymerase epsilon catalytic subunit A 0.074 0.074
WDR57 WDR57, PRP8BP, SFP38: WD repeat-containing protein 57 0.074 0.123
WDR77 WDR77, HKMT1069, hCG_39991: Androgen receptor cofactor p44 0.074 0.263
DHX35 C20orf15, DHX35, DDX35: Probable ATP-dependent RNA helicase DHX35 0.074 0.044
DDX19A DDX19A, DDX19L: ATP-dependent RNA helicase DDX19A 0.074 0.074
DDX10 DDX10: Probable ATP-dependent RNA helicase DDX10 0.074 0.074
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.070 0.052
WDR8 WDR8: WD repeat-containing protein 8 0.067 0.067
RAD54B RAD54B: DNA repair and recombination protein RAD54B 0.067 0.067
PHF20 PHF20, C20orf104, GLEA2, HCA58, NZF, TZP: PHD finger protein 20 0.065 0.032
NUP214 N/A 0.064 0.152
H2AFX H2AFX, H2AX: Histone H2A.x 0.063 0.078
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.078
WDR67 WDR67: WD repeat-containing protein 67 0.060 0.036
WDR26 WDR26, CDW2, PRO0852, MIP2: WD repeat-containing protein 26 0.060 0.028
CORO7 CORO7: Coronin-7 0.060 0.044
WIPI2 WIPI2, CGI-50: WD repeat domain phosphoinositide-interacting protein 2 0.060 0.044
RAE1 RAE1, MRNP41: mRNA export factor 0.060 0.036
XPMC2H REXO4, PMC2, XPMC2H: RNA exonuclease 4 0.060 0.060
AAAS AAAS, ADRACALA, GL003: Aladin 0.060 0.044
HELLS HELLS, PASG, Nbla10143, SMARCA6: Lymphoid-specific helicase 0.060 0.123
POLA POLA1, POLA: DNA polymerase alpha catalytic subunit 0.060 0.044
PWP2H PWP2, PWP2H: Periodic tryptophan protein 2 homolog 0.060 0.074
DDX17 DDX17: Probable ATP-dependent RNA helicase DDX17 0.060 0.044
PIK3R4 PIK3R4: Phosphoinositide 3-kinase regulatory subunit 4 0.060 0.044
WDR39 CIAO1, WDR39: Protein CIAO1 0.060 0.074
RECQL4 RECQL4, RECQ4: ATP-dependent DNA helicase Q4 0.060 0.036
DHX38 DHX38, DDX38, KIAA0224, PRP16: Pre-mRNA-splicing factor ATP-dependent RNA helica 0.060 0.044
GRWD1 GRWD1, GRWD, WDR28: Glutamate-rich WD repeat-containing protein 1 0.060 0.060
IFIH1 IFIH1, MDA5, RH116: Interferon-induced helicase C domain-containing protein 1 0.060 0.060
DDX28 DDX28, MDDX28: Probable ATP-dependent RNA helicase DDX28 0.060 0.074
CNOT8 CNOT8, CALIF, POP2: CCR4-NOT transcription complex subunit 8 0.060 0.036
RNU3IP2 RRP9, RNU3IP2, U355K: U3 small nucleolar RNA-interacting protein 2 0.060 0.074
DYNC1I2 N/A 0.058 0.037
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.058 0.136
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.058 0.171
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.058 0.136
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.056 0.165
WDR54 N/A 0.056 0.165
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.056 0.056
PTMA N/A 0.054 0.087
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.054 0.144
SET SET: Protein SET 0.054 0.144
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.054 0.144
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.054 0.144
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.054 0.054
SH3BP3 0.051 0.037
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.050 0.148
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.050 0.075
GEMIN5 GEMIN5: Gem-associated protein 5 0.050 0.148
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.050 0.148
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.050 0.148
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.050 0.148
GNB4 GNB4: Guanine nucleotide-binding protein subunit beta-4 0.050 0.050
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.050 0.148
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.050 0.148
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.050 0.148
CETN1 CETN1, CEN1, CETN: Centrin-1 0.050 0.148
DDB2 DDB2: DNA damage-binding protein 2 0.050 0.083
ISG20 ISG20, HEM45: Interferon-stimulated gene 20 kDa protein 0.050 0.050
GNB1L GNB1L, GY2, FKSG1, KIAA1645, WDR14: Guanine nucleotide-binding protein subunit b 0.050 0.050
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.048 0.129
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.048 0.078
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.048 0.129
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.048 0.078
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.048 0.078
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.048 0.063
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.048 0.129
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.048 0.129
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.048 0.063
PPP1R8 N/A 0.048 0.063
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.048 0.078
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.048 0.129
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.048 0.129
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.048 0.078
CBX3 CBX3: Chromobox protein homolog 3 0.048 0.078
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.048 0.078
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.048 0.078
NUTF2 NUTF2, NTF2: Nuclear transport factor 2 0.047 0.0968
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.046 0.029
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.046 0.029
WDR48 WDR48, KIAA1449: WD repeat-containing protein 48 0.044 0.028
TTF2 TTF2: Transcription termination factor 2 0.044 0.060
EML3 EML3: Echinoderm microtubule-associated protein-like 3 0.044 0.060
DDX56 DDX56, DDX21, NOH61: Probable ATP-dependent RNA helicase DDX56 0.044 0.044
DDX52 DDX52, ROK1, HUSSY-19: Probable ATP-dependent RNA helicase DDX52 0.044 0.028
THRAP5 MED16, DRIP92, THRAP5: Mediator of RNA polymerase II transcription subunit 16 0.044 0.060
AAMP AAMP: Angio-associated migratory cell protein 0.044 0.060
LGP2 DHX58, D11LGP2E, LGP2: Probable ATP-dependent RNA helicase DHX58 0.044 0.036
CORO1A CORO1A, CORO1: Coronin-1A 0.044 0.044
REV3L REV3L, POLZ, REV3: DNA polymerase zeta catalytic subunit 0.041 0.041
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.038 0.038
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.038 0.029
ARPC1A ARPC1A, SOP2L: Actin-related protein 2/3 complex subunit 1A 0.036 0.044
SETDB1 SETDB1, KIAA0067: Histone-lysine N-methyltransferase SETDB1 0.036 0.036
NBEAL2 N/A 0.036 0.044
WDR42A N/A 0.036 0.036
WDR37 N/A 0.036 0.028
WDR45L N/A 0.036 0.036
PARN PARN, DAN: Poly(A)-specific ribonuclease PARN 0.036 0.060
POLG POLG, MDP1, POLG1, POLGA: DNA polymerase subunit gamma-1 0.0331 0.0331
RNASEH1 RNASEH1, RNH1: Ribonuclease H1 0.0331 0.0331
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.033 0.032
CCT8 CCT8: Uncharacterized protein CCT8 0.033 0.066
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.033 0.040
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.033 0.066
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.033 0.066
SAT SAT1, SAT: Diamine acetyltransferase 1 0.032 0.026
WDR13 WDR13: WD repeat-containing protein 13 0.0308 0.041
SMARCA1 SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1 0.0296 0.099
CREBBP CREBBP, CBP: CREB-binding protein 0.029 0.029
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
SNRPB N/A 0.028 0.028
KATNB1 KATNB1: Katanin p80 WD40-containing subunit B1 0.028 0.028
PEX7 PEX7, PTS2R: Peroxisomal targeting signal 2 receptor 0.028 0.036
LBR LBR: Lamin-B receptor 0.027 0.027
WDR53 N/A 0.027 0.027
ERCC8 ERCC8, CKN1, CSA: DNA excision repair protein ERCC-8 0.027 0.027
DDX53 DDX53, CAGE: Probable ATP-dependent RNA helicase DDX53 0.027 0.027
WDR34 N/A 0.027 0.027
TLE6 TLE6: Transducin-like enhancer protein 6 0.027 0.027
TAF5L TAF5L, PAF65B: TAF5-like RNA polymerase II p300/CBP-associated factor-associated 0.027 0.027
FBXW8 FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6: F-box/WD repeat-containing protein 8 0.027 0.027
WDR72 N/A 0.027 0.027
REXO1L1 REXO1L1, GOR: Exonuclease GOR 0.027 0.027
FLJ12671 ISG20L2, HSD38, HSD-38: Interferon-stimulated 20 kDa exonuclease-like 2 0.027 0.027
BRWD1 N/A 0.027 0.027
PHF1 N/A 0.027 0.027
TREX1 TREX1: Three prime repair exonuclease 1 0.027 0.027
NEDD1 N/A 0.027 0.027
WDR17 N/A 0.027 0.027
RFWD2 RFWD2, COP1, RNF200: E3 ubiquitin-protein ligase RFWD2 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
TDRD4 TDRD4: Tudor domain-containing protein 4 0.027 0.027
KIF21A N/A 0.027 0.027
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.027 0.036
SNRPB N/A 0.0258 0.0258
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.025 0.307
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.025 0.070
ABCF1 N/A 0.025 0.144
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.025 0.144
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.025 0.070
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.025 0.070
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.025 0.087
MATR3 MATR3, KIAA0723: Matrin-3 0.025 0.070
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.025 0.087
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
0.572
Total Score 1.78E5