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Evidence of Interaction Between EPOR and WASL

The interaction score between EPOR and WASL is 3.34.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EPOR and WASL = 0.00

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

1.85E-3
Orthology N/A N/A
Domains Domains present in EPOR and WASL:
Domains in EPORDomains in WASL
IPR003961 Fibronectin, type III
IPR003528 Long hematopoietin receptor, single chain
IPR009167 Erythropoietin receptor
IPR002996 Cytkn_recept_B/G.
IPR003124 Actin-binding WH2
IPR000095 PAK-box/P21-Rho-binding
IPR011026 Wiscott-Aldrich syndrome, C-terminal
IPR000697 EVH1
IPR011993 PH_type.

The Chi square scores for co-occurrence of domains that are present in EPOR and WASL are listed below.

Domain 1Domain 2Chi Square
IPR003961 Fibronectin, type III IPR011993 PH_type. 3.27464
IPR003528 Long hematopoietin receptor, single chain IPR011993 PH_type. 0.89194
IPR002996 Cytkn_recept_B/G. IPR011993 PH_type. 0.141797

The background colour of the table refers to:

  • Blue Domain is only present in EPOR
  • Yellow Domain is only present in WASL
  • Green Domain is present in both EPOR and WASL

0.049
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: WASL

PTMResidueReference
Phosphorylation 175 PubMed, HPRD
Phosphorylation 256 PubMed, HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: WASL

LocalisationReference
Nucleolus HPRD
Secreted HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between EPOR and WASL that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andWASL. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and WASL has 970 interactors of which there are 578 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for WASL-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.109
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.541 0.109
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.253 0.049
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.251 0.072
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.0453
CRLF3 N/A 0.191 0.032
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.166 0.097
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.097
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.166 0.111
CNTN1 CNTN1: Contactin-1 precursor 0.165 0.044
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.109
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.165 0.036
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.049
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.049
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.036
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.049
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.049
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.098
CNTN4 CNTN4: Contactin-4 precursor 0.165 0.044
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.049
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.04
FN1 N/A 0.165 0.049
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.049
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.044
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.049
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.109
BSG N/A 0.165 0.044
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.165 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.044
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.098
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.049
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.165 0.044
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.153 0.111
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.153 0.097
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.152 0.073
KIT KIT: Mast/stem cell growth factor receptor precursor 0.152 0.064
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.152 0.037
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 0.097
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 0.111
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.126 0.097
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.126 0.025
CD2AP CD2AP: CD2-associated protein 0.126 29.20
CRKL CRKL: Crk-like protein 0.126 5.88
RDX RDX: Radixin 0.126 0.049
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.111
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.077
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.124 0.097
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.123 0.037
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.123 0.032
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.123 0.090
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.090
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.123 0.064
INSR INSR: Insulin receptor precursor 0.123 0.073
IL9R IL9R: Interleukin-9 receptor precursor 0.123 0.037
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.123 0.073
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.123 0.033
GHR GHR: Growth hormone receptor precursor 0.123 0.0453
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.123 0.100
DCC DCC: Netrin receptor DCC precursor 0.123 0.029
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.032
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.037
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.0453
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.064
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.051
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.075
ELMO1 N/A 0.109 0.075
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.034
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 0.025
ARHGEF7 N/A 0.109 0.075
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.148
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.075
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.165
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.062
NF2 NF2, SCH: Merlin 0.109 0.083
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.075
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 0.148
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.083
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.148
STAT3 0.109 0.148
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 7.88
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.083
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.148
MAPK15 N/A 0.109 0.165
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 199.00
PSCD2 N/A 0.109 0.083
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.148
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.148
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 39.20
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.148
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.148
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 0.025
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.081
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.100
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 0.064
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.032
TNC TNC, HXB: Tenascin precursor 0.109 0.029
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.0453
ITGB4 N/A 0.109 0.081
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.109 0.100
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.109 0.064
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.136
SORL1 SORL1: Sortilin-related receptor precursor 0.109 0.033
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.109 0.0453
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.109 0.037
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.109 0.029
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.109 0.037
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.037
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.109 0.090
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.109 0.073
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.109 0.041
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.123
PRLR PRLR: Prolactin receptor precursor 0.109 0.057
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.109 0.029
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 0.073
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.032
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.073
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.109 0.029
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.109 0.090
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.081
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.123
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 0.097
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 5.88
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 0.111
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.111
RPS6KB1 N/A 0.100 0.111
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 0.111
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.100 0.088
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 0.097
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.056
TLN1 TLN1: Uncharacterized protein TLN1 0.100 0.049
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.049
DOK1 DOK1: Docking protein 1 0.100 0.056
PLD2 PLD2: Phospholipase D2 0.100 0.056
NEO1 NEO1, NGN: Neogenin precursor 0.098 0.064
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.073
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.098 0.073
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.098 0.064
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.098 0.064
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.098 0.0453
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.098 0.073
PTPRZ1 N/A 0.098 0.029
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.032
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.098 0.041
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.032
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.098 0.064
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.073
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.098 0.032
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.096 0.090
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.091 0.111
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.091 0.111
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.091 0.026
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.091 0.097
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.148
KIR3DL1 N/A 0.083 0.049
CDH6 CDH6: Cadherin-6 precursor 0.083 0.049
DLK1 DLK1, DLK: Delta-like protein precursor 0.083 0.049
ATRN N/A 0.083 0.098
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.109
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.083 0.044
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.04
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 0.098
JAG2 JAG2: Jagged-2 precursor 0.083 0.044
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.083 0.109
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.069
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 5.88
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 0.111
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.077
TLN2 TLN2: Uncharacterized protein TLN2 0.081 0.056
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.109
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.025
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.111
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.081 0.111
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.081 0.109
HCK N/A 0.081 5.18
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.111
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.097
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.097
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.097
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.136
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.056
DLG2 DLG2: Disks large homolog 2 0.081 0.041
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.081 0.111
SYK SYK: Tyrosine-protein kinase SYK 0.081 0.111
SORBS3 SORBS3, SCAM1: Vinexin 0.081 5.18
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.109
STK16 N/A 0.081 0.109
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.077 0.111
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.077 0.081
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.075 0.097
CDK2 CDK2: Cell division protein kinase 2 0.075 0.111
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.097
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.111
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.075 0.097
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.111
WEE1 WEE1: Wee1-like protein kinase 0.075 0.111
SPTAN1 N/A 0.0727 0.109
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 0.136
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.136
MSN MSN: Moesin 0.072 0.056
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 0.111
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 5.18
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.097
FNBP1 N/A 0.072 7.26
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 5.88
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 5.88
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.097
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 0.123
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.072 0.111
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.069
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 0.123
JAK1 0.072 0.111
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 0.152
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 0.111
PLD1 PLD1: Phospholipase D1 0.072 0.056
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 5.88
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.099
ALK ALK: ALK tyrosine kinase receptor precursor 0.072 0.041
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 0.123
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.123
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.123
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.055
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.123
CSK CSK: Tyrosine-protein kinase CSK 0.072 0.111
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.072 0.046
PSD TYL: TYL protein 0.072 0.049
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.056
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.111
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.109
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.062
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.025
CXorf9 N/A 0.072 0.111
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.152
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.062
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.152
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.072 0.035
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.109
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.056
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.097
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 0.111
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.123
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.072 0.041
TTN N/A 0.072 0.056
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.072 0.025
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.072 0.088
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.072 0.037
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.072 0.041
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.123
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.097
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 127.00
BMX N/A 0.072 0.123
LYN LYN: Tyrosine-protein kinase Lyn 0.072 0.111
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.055
VIL2 N/A 0.072 0.069
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.109
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.109
GAB2 N/A 0.072 0.055
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.098
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.098
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.044
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.111
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.111
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 131.00
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.111
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.111
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.056
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.123
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.109
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.065 0.049
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 0.136
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.136
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.062
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.065 0.123
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.097
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.056
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.111
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.073
MEP1A MEP1A: Meprin A subunit alpha precursor 0.062 0.033
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.062 0.072
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.062 0.0453
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.062 0.037
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.097
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.062 0.037
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.073
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.062 0.037
SELE SELE, ELAM1: E-selectin precursor 0.062 0.037
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.062 0.033
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.062 0.072
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.062 0.064
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.062 0.064
CD44 N/A 0.062 0.032
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.029
CDK4 CDK4: Cell division protein kinase 4 0.057 0.097
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.057 0.111
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.097
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.057 0.123
CDK6 CDK6: Cell division protein kinase 6 0.057 0.111
DYRK3 N/A 0.057 0.097
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.056 0.097
F10 F10: Coagulation factor X precursor 0.055 0.033
EGF EGF: Pro-epidermal growth factor precursor 0.055 0.100
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.055 0.037
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.055 0.032
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.055 0.081
ITGAE ITGAE: Integrin alpha-E precursor 0.055 0.032
MEP1B MEP1B: Meprin A subunit beta precursor 0.055 0.029
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.055 0.032
CDH5 CDH5: Cadherin-5 precursor 0.055 0.0453
AREG AREG, SDGF: Amphiregulin precursor 0.055 0.032
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.055 0.072
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.055 0.032
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.055 0.032
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.055 0.073
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.055 0.029
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.055 0.073
UMOD UMOD: Uromodulin precursor 0.055 0.037
CDH2 CDH2, CDHN, NCAD: Cadherin-2 precursor 0.055 0.029
LDLR LDLR: Low-density lipoprotein receptor precursor 0.055 0.029
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.055 0.073
NOTCH4 N/A 0.055 0.041
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.055 0.033
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.055 0.033
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.055 0.037
ITGB7 ITGB7: Integrin beta-7 precursor 0.055 0.090
GNA12 GNA12: Guanine nucleotide-binding protein alpha-12 subunit 0.052 0.033
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.051 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.051 0.046
FLT4 VEGFR3 long form 0.051 0.046
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 2.45
DLG1 DLG1: Disks large homolog 1 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.051
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.051 0.046
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.051
GRB10 N/A 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.073
ITGAV ITGAV, MSK8, VNRA: Integrin alpha-V precursor 0.049 0.026
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.049 0.041
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.049 0.029
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.049 0.037
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.049 0.073
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.049 0.032
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.049 0.032
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.165
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.148
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.083
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.148
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.165
MAPKAPK5 N/A 0.049 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.083
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.049 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.049 0.075
PLAT PLAT: Tissue-type plasminogen activator precursor 0.049 0.030
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.148
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.165
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.075
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.075
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.049 0.030
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.049 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.049 0.075
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.148
PPEF1 N/A 0.049 0.083
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.165
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.148
F7 F7: Coagulation factor VII precursor 0.049 0.030
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.148
BMP1 N/A 0.049 0.030
MAP2K5 N/A 0.049 0.165
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.049 0.075
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.165
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.148
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.148
SNX3 N/A 0.049 0.047
CNN2 CNN2: Calponin-2 0.049 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.075
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.148
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.165
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.0453 0.056
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 0.111
DAB1 DAB1: Disabled homolog 1 0.0453 0.049
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.097
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.109
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0453 0.136
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.109
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0453 0.123
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.0453 0.111
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.072
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 0.081
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.081
PLEK PLEK, P47: Pleckstrin 0.045 0.037
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.073
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.045 0.090
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.073
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.058
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.04 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.04 0.075
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 0.039 0.037
CDK7 CDK7, MO15: Cell division protein kinase 7 0.037 0.097
C8B C8B: Complement component C8 beta chain precursor 0.037 0.028
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.037 0.123
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.037 0.055
CSPG2 N/A 0.037 0.025
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.037 0.088
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.037 0.031
MUC2 MUC2, SMUC: Mucin-2 precursor 0.037 0.025
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.037 0.056
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.037 0.111
CFB CFB, BF, BFD: Complement factor B precursor 0.037 0.025
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.037 0.111
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.152
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.111
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.037 0.056
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.037 0.136
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.037 0.056
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.037 0.035
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.136
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.111
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.037 0.034
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.056
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.109
AMBP AMBP, HCP, ITIL: AMBP protein precursor [Contains: Alpha-1-microglobulin 0.037 0.025
STK10 STK10: Uncharacterized protein STK10 0.037 0.111
C2 C2: Complement C2 precursor 0.037 0.031
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.037 0.136
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.037 0.152
F9 F9: Coagulation factor IX precursor 0.037 0.028
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.055
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.111
C8A C8A: Complement component C8 alpha chain precursor 0.037 0.025
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.037 0.123
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.0794
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.136
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.037 0.111
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.111
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.0338 0.042
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.098
PTGS1 PTGS1, COX1: Prostaglandin G/H synthase 1 precursor 0.034 0.034
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.034 0.044
CETN1 CETN1, CEN1, CETN: Centrin-1 0.034 0.044
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.033 0.0416
S100B S100B: Protein S100-B 0.032 0.055
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.032 0.049
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.032 0.049
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.123
LCP1 LCP1, PLS2: Plastin-2 0.032 2.96
F12 F12: Coagulation factor XII precursor 0.032 0.025
C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 0.032 0.028
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.136
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.032 0.056
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.123
MYL3 MYL3: Myosin light polypeptide 3 0.032 0.049
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.032 0.056
GRLF1 N/A 0.032 0.109
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.032 0.063
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.032 0.056
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.086
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.032 0.049
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.088
CHP CHP: Calcium-binding protein p22 0.032 0.049
S100A7 S100A7, PSOR1: Protein S100-A7 0.032 0.055
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.032 0.136
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.152
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.032 0.109
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.136
DAB2 DAB2, DOC2: Disabled homolog 2 0.032 0.069
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.111
PRKAA1 N/A 0.032 0.123
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.097
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 0.171
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.032 29.20
PMP2 PMP2: Myelin P2 protein 0.032 0.056
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.123
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.111
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.136
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.032 0.056
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.032 0.171
ATM ATM: Serine-protein kinase ATM 0.032 0.111
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.111
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.055
GMIP GMIP: GEM-interacting protein 0.032 0.056
CDKL5 N/A 0.032 0.152
C1R C1R: Complement C1r subcomponent precursor 0.032 0.025
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.109
MYO3A MYO3A: Myosin IIIA 0.032 0.111
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.032 0.049
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.097
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.056
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.032 0.136
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.097
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.171
ACTN1 ACTN1: Alpha-actinin-1 0.032 0.044
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.032 0.045
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.032 0.063
S100A3 S100A3, S100E: Protein S100-A3 0.032 0.062
DAPK2 DAPK2: Death-associated protein kinase 2 0.032 0.123
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.032 0.056
MDN1 MDN1, KIAA0301: Midasin 0.030 0.049
CDK5 CDK5: Cell division protein kinase 5 0.029 0.097
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.111
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.097
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.111
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.029 0.069
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.029 0.136
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.029 0.046
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.029 0.055
CNN3 CNN3: Calponin-3 0.029 0.029
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.111
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.136
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.056
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.029 0.046
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.111
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.029 0.051
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.056
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.136
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.097
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.111
PCDHA2 PCDHA2: Protocadherin alpha 2 precursor 0.028 0.049
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.028 0.044
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.04
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.028 0.098
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
DRD2 DRD2: D(2) dopamine receptor 0.028 0.049
TMPRSS9 N/A 0.028 0.044
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.049
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.049
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.044
MUCDHL MUPCDH, MUCDHL, UNQ2781/PRO7168: Mucin and cadherin-like protein precursor 0.028 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.049
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.098
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
ITIH4 ITIH4, IHRP, PRO1851, ITIHL1, PK120: Inter-alpha-trypsin inhibitor heavy chain H 0.0263 0.025
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.026 0.0263
RHO RHO, OPN2: Rhodopsin 0.026 0.0453
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.026 0.064
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.025 0.027
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.073
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.081
ETS2 ETS2: Protein C-ets-2 0.025 0.037
0.228
Total Score 3.34