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Evidence of Interaction Between EPOR and MKNK1

The interaction score between EPOR and MKNK1 is 5.87.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

N/A
Orthology N/A N/A
Domains Domains present in EPOR and MKNK1:
Domains in EPORDomains in MKNK1
IPR003961 Fibronectin, type III
IPR003528 Long hematopoietin receptor, single chain
IPR009167 Erythropoietin receptor
IPR002996 Cytkn_recept_B/G.
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR008271 Serine/threonine protein kinase, active site

The Chi square scores for co-occurrence of domains that are present in EPOR and MKNK1 are listed below.

Domain 1Domain 2Chi Square
IPR003961 Fibronectin, type III IPR008271 Serine/threonine protein kinase, active site 30.5883
IPR003961 Fibronectin, type III IPR002290 Serine/threonine protein kinase 13.198
IPR002996 Cytkn_recept_B/G. IPR002290 Serine/threonine protein kinase 2.93674
IPR003528 Long hematopoietin receptor, single chain IPR000719 Protein kinase 1.94307
IPR002996 Cytkn_recept_B/G. IPR000719 Protein kinase 1.43014
IPR009167 Erythropoietin receptor IPR000719 Protein kinase 0.93762
IPR003961 Fibronectin, type III IPR000719 Protein kinase 0.712801

The background colour of the table refers to:

  • Blue Domain is only present in EPOR
  • Yellow Domain is only present in MKNK1
  • Green Domain is present in both EPOR and MKNK1

0.049
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: MKNK1

PTMResidueReference
Phosphorylation 39 PubMed, HPRD
Phosphorylation 191 PubMed, HPRD
Phosphorylation 250 PubMed, HPRD
Phosphorylation 255 PubMed, HPRD
Phosphorylation 385 PubMed, HPRD
Phosphorylation 437 PubMed, HPRD
Phosphothreonine 250 PubMed, HPRD
Phosphothreonine 255 PubMed, HPRD
Phosphothreonine 385 PubMed, HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: MKNK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between EPOR and MKNK1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andMKNK1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and MKNK1 has 1681 interactors of which there are 522 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for MKNK1-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.028
SLC4A1 SLC4A1, AE1, DI, EPB3: Band 3 anion transport protein 0.923 0.036
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.541 0.028
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.340 0.148
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.253 0.025
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.251 0.028
HSP90AA1 Hsp89-alpha-delta-N 0.202 0.075
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.049
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.166 0.025
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.075
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.166 0.025
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.165 0.098
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.049
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.049
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.049
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.098
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
CAT CAT: Catalase 0.157 0.025
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.153 0.025
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.153 0.025
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.152 0.049
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 0.025
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.126 0.025
TAL1 TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1 0.126 0.025
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 0.148
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.126 0.025
CD2AP CD2AP: CD2-associated protein 0.126 0.025
CRKL CRKL: Crk-like protein 0.126 0.148
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.126 0.062
RDX RDX: Radixin 0.126 0.148
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.025
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.165
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.125 0.025
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.125 0.025
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.124 0.047
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.124 0.025
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.036
IL9R IL9R: Interleukin-9 receptor precursor 0.123 0.049
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.123 0.098
GHR GHR: Growth hormone receptor precursor 0.123 0.049
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.049
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.098
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.148
ELMO1 N/A 0.109 0.148
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.034
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 0.148
ARHGEF7 N/A 0.109 0.148
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.025
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.148
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.165
NF2 NF2, SCH: Merlin 0.109 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.148
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.028
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 0.075
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.025
STAT3 0.109 0.148
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 0.148
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.148
MAPK15 N/A 0.109 0.083
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 0.148
PSCD2 N/A 0.109 0.165
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.148
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.025
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 0.025
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.047
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.025
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.025
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.025
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.052
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 0.148
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.049
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.049
ITGB4 N/A 0.109 0.049
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.049
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.148
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.109 0.049
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.109 0.109
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.109 0.098
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.049
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.028
PRLR PRLR: Prolactin receptor precursor 0.109 0.049
F3 F3: Tissue factor precursor 0.109 0.049
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.049
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.044
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.165
CP CP: Ceruloplasmin precursor 0.100 0.034
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.083
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 0.148
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 0.148
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 0.148
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.075
RPS6KB1 N/A 0.100 0.025
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 0.148
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.100 0.025
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 0.025
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.148
TLN1 TLN1: Uncharacterized protein TLN1 0.100 0.025
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.148
DOK1 DOK1: Docking protein 1 0.100 0.148
PLD2 PLD2: Phospholipase D2 0.100 0.148
PTPRZ1 N/A 0.098 0.098
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.049
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.098 0.098
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.091 0.075
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.091 0.025
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.091 0.083
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.091 0.025
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.087 0.044
SLC2A1 SLC2A1, GLUT1: Solute carrier family 2, facilitated glucose transporter member 1 0.087 0.036
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.025
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.083 0.044
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.083 0.049
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.083 0.049
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.148
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 0.148
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 0.148
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.165
TLN2 TLN2: Uncharacterized protein TLN2 0.081 0.025
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.165
F5 F5: Coagulation factor V precursor 0.081 0.034
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.034
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.148
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.081 0.025
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.081 0.165
HCK N/A 0.081 0.148
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.148
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.148
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.081 0.083
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.148
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.148
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.075
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.081 0.030
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.148
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.081 0.025
SYK SYK: Tyrosine-protein kinase SYK 0.081 0.148
SORBS3 SORBS3, SCAM1: Vinexin 0.081 0.025
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.165
STK16 N/A 0.081 0.028
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.077 0.025
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.075 0.025
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.075 0.025
CDK2 CDK2: Cell division protein kinase 2 0.075 0.025
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.025
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.025
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.075 0.025
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.025
WEE1 WEE1: Wee1-like protein kinase 0.075 0.025
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.074 0.028
SPTAN1 N/A 0.0727 0.028
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 0.148
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.025
MSN MSN: Moesin 0.072 0.148
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 0.025
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 0.148
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.025
FNBP1 N/A 0.072 0.025
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 0.148
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 0.148
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.025
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 0.165
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.072 0.025
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.148
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 0.165
JAK1 0.072 0.148
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 0.165
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 0.075
PLD1 PLD1: Phospholipase D1 0.072 0.148
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 0.148
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.083
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 0.165
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.028
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.165
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.165
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.165
CSK CSK: Tyrosine-protein kinase CSK 0.072 0.148
PSD TYL: TYL protein 0.072 0.148
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.148
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.148
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.083
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.165
CXorf9 N/A 0.072 0.025
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.028
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.165
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.028
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.072 0.148
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.165
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.148
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.148
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 0.148
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.165
TTN N/A 0.072 0.025
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.072 0.075
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.165
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.148
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.148
BMX N/A 0.072 0.165
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.072 0.062
LYN LYN: Tyrosine-protein kinase Lyn 0.072 0.148
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.165
VIL2 N/A 0.072 0.148
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.028
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.165
GAB2 N/A 0.072 0.165
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.075
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.0688 0.148
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.148
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.148
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.075
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.148
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 0.148
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.148
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.148
F8 F8, F8C: Coagulation factor VIII precursor 0.065 0.034
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.148
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.165
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.028
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.065 0.148
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 0.075
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.148
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.165
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.065 0.028
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.148
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.148
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.148
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.148
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.062 0.049
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.075
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.062 0.049
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.036
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.062 0.044
CD44 N/A 0.062 0.049
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.025
CDK4 CDK4: Cell division protein kinase 4 0.057 0.025
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.057 0.025
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.148
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.057 0.028
CDK6 CDK6: Cell division protein kinase 6 0.057 0.025
DYRK3 N/A 0.057 0.025
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.056 0.025
EGF EGF: Pro-epidermal growth factor precursor 0.055 0.049
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.055 0.049
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.055 0.049
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.055 0.044
PTPRA N/A 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
RAPH1 N/A 0.051 0.051
C9orf88 N/A 0.051 0.051
EPB41 EPB41, E41P: Protein 4.1 0.051 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.051 0.046
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.051 0.046
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
GRB10 N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.051 0.046
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.051 0.148
TP73 TP73, P73: Tumor protein p73 0.051 0.028
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.148
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.0513 0.075
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.049 0.049
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.083
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.025
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.028
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.025
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.083
MAPKAPK5 N/A 0.049 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.028
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.049 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.049 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.148
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.028
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.025
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.052
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.075
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.049 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.049 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.025
PPEF1 N/A 0.049 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.083
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.025
MAP2K5 N/A 0.049 0.165
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.025
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.049 0.025
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.028
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.075
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.028
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.025
SNX3 N/A 0.049 0.075
CNN2 CNN2: Calponin-2 0.049 0.083
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.025
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.075
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.075
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.028
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.046
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.046 0.165
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.0453 0.148
FUBP1 N/A 0.0453 0.028
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 0.075
DAB1 DAB1: Disabled homolog 1 0.0453 0.148
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.075
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.028
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.0453 0.075
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0453 0.025
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.083
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0453 0.028
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.0453 0.025
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.0453 0.025
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.165
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 0.165
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.165
PLEK PLEK, P47: Pleckstrin 0.045 0.165
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.148
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.045 0.148
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.0446 0.025
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.0446 0.025
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.0446 0.025
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.0446 0.025
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.044 0.050
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.042 0.025
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.042 0.025
PCAF PCAF: Histone acetyltransferase PCAF 0.042 0.025
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.148
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.148
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.148
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.0688
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.04 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.04 0.075
CDC20 CDC20: Cell division cycle protein 20 homolog 0.039 0.075
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.039 0.049
CDKN3 CDKN3, CDI1, CIP2, KAP: Cyclin-dependent kinase inhibitor 3 0.039 0.027
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.039 0.025
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.039 0.025
XRCC1 XRCC1: DNA-repair protein XRCC1 0.039 0.028
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.038 0.046
TBCE TBCE: Tubulin-specific chaperone E 0.037 0.025
COPA COPA: Coatomer subunit alpha 0.037 0.025
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.037 0.025
CDK7 CDK7, MO15: Cell division protein kinase 7 0.037 0.025
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.037 0.028
FLII FLII, FLIL: Protein flightless-1 homolog 0.037 0.025
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.037 0.028
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.037 0.148
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.037 0.028
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.037 0.025
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.037 0.025
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.037 0.025
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.037 35.90
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.028
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.075
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.037 0.148
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.037 0.025
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.037 0.025
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.037 0.075
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.025
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.025
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.037 0.028
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.025
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.165
STK10 STK10: Uncharacterized protein STK10 0.037 0.025
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.037 0.025
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.037 0.028
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.028
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.075
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.037 0.028
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.025
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.037 0.025
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.025
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.036 0.025
CSDA CSDA, DBPA: DNA-binding protein A 0.036 0.025
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.036 0.052
TK1 TK1: Thymidine kinase, cytosolic 0.036 0.025
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.034 0.049
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.047
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.075
CETN1 CETN1, CEN1, CETN: Centrin-1 0.034 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.034 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.034 0.025
NDP NDP: Norrin precursor 0.033 0.0688
S100B S100B: Protein S100-B 0.032 0.028
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.032 0.025
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.032 0.025
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.083
LCP1 LCP1, PLS2: Plastin-2 0.032 0.025
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.075
VWF VWF, F8VWF: von Willebrand factor precursor 0.032 0.062
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.075
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.032 0.025
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.052
MYL3 MYL3: Myosin light polypeptide 3 0.032 0.025
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.032 0.025
GRLF1 N/A 0.032 0.083
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.032 0.025
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.148
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.032 0.025
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.025
CHP CHP: Calcium-binding protein p22 0.032 0.025
S100A7 S100A7, PSOR1: Protein S100-A7 0.032 0.028
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.032 0.025
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.028
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.032 0.028
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.075
DAB2 DAB2, DOC2: Disabled homolog 2 0.032 0.148
PAEP PAEP: Glycodelin precursor 0.032 0.028
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.025
PRKAA1 N/A 0.032 0.028
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.075
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 0.025
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.032 0.148
PMP2 PMP2: Myelin P2 protein 0.032 0.025
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.028
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.025
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.025
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.032 0.025
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.032 0.025
ATM ATM: Serine-protein kinase ATM 0.032 0.075
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.025
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.028
GMIP GMIP: GEM-interacting protein 0.032 0.075
CDKL5 N/A 0.032 0.028
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.028
MYO3A MYO3A: Myosin IIIA 0.032 0.025
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.032 0.025
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.148
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.075
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.032 0.025
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.025
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.075
ACTN1 ACTN1: Alpha-actinin-1 0.032 0.025
S100A3 S100A3, S100E: Protein S100-A3 0.032 0.028
DAPK2 DAPK2: Death-associated protein kinase 2 0.032 0.028
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.032 0.025
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.032 0.028
FRMD4A RP11-397C18.4, RP11-397C18.4-003: Novel protein 0.032 0.027
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.031 0.025
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.031 0.025
TP53 TP53, P53: Cellular tumor antigen p53 0.031 0.025
DYNC1I2 N/A 0.030 0.025
MDN1 MDN1, KIAA0301: Midasin 0.030 0.025
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.030 0.025
PLEK2 PLEK2: Pleckstrin-2 0.030 0.027
CDK5 CDK5: Cell division protein kinase 5 0.029 0.025
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.025
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.025
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.075
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.029 0.025
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.029 0.075
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.029 0.028
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.029 0.075
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.029 0.034
CNN3 CNN3: Calponin-3 0.029 0.083
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.075
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.075
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.148
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.029 0.030
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.025
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.025
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.075
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.025
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.025
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.029 0.050
AQP4 AQP4: Aquaporin-4 0.028 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.028 0.044
TBXA2R TBXA2R: Thromboxane A2 receptor 0.028 0.04
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.028 0.04
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.028 0.049
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.028 0.049
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.049
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.028 0.044
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.049
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.098
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.049
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.028 0.049
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.049
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.044
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.027 0.025
RACGAP1 RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1 0.027 0.025
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.027 0.025
THOC1 THOC1, HPR1: THO complex subunit 1 0.027 0.075
CA3 CA3: Carbonic anhydrase 3 0.027 0.025
AQP1 AQP1, CHIP28: Aquaporin-1 0.027 0.075
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.027 0.025
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.0263 0.025
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0263 0.083
SLC2A2 SLC2A2, GLUT2: Solute carrier family 2, facilitated glucose transporter member 2 0.026 0.036
RHO RHO, OPN2: Rhodopsin 0.026 0.049
FADD FADD, MORT1: Protein FADD 0.026 0.049
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.025 0.075
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.075
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.028
NUP214 N/A 0.025 0.028
ETS2 ETS2: Protein C-ets-2 0.025 0.083
GNB2L1 Lung cancer oncogene 7 0.025 0.028
0.299
Total Score 5.87