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Evidence of Interaction Between EPOR and DUSP1

The interaction score between EPOR and DUSP1 is 7.12.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EPOR and DUSP1 = 0.05

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.85E-3
Orthology N/A N/A
Domains Domains present in EPOR and DUSP1:
Domains in EPORDomains in DUSP1
IPR003961 Fibronectin, type III
IPR003528 Long hematopoietin receptor, single chain
IPR009167 Erythropoietin receptor
IPR002996 Cytkn_recept_B/G.
IPR000387 Tyrosine specific protein phosphatase and dual specificity protein phosphatase
IPR001763 Rhodanese-like
IPR000340 Dual specificity protein phosphatase
IPR008343 MAP kinase phosphatase

The Chi square scores for co-occurrence of domains that are present in EPOR and DUSP1 are listed below.

Domain 1Domain 2Chi Square
IPR003961 Fibronectin, type III IPR000387 Tyrosine specific protein phosphatase and dual specificity protein phosphatase 7.51945
IPR002996 Cytkn_recept_B/G. IPR000387 Tyrosine specific protein phosphatase and dual specificity protein phosphatase 4.82057

The background colour of the table refers to:

  • Blue Domain is only present in EPOR
  • Yellow Domain is only present in DUSP1
  • Green Domain is present in both EPOR and DUSP1

 0.069
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: DUSP1

PTMResidueReference
Phosphorylation 359 PubMed, HPRD
Phosphorylation 364 PubMed, HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: DUSP1

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between EPOR and DUSP1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andDUSP1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and DUSP1 has 1224 interactors of which there are 527 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for DUSP1-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.037
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.541 0.251
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.251 0.152
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.210 0.128
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.046
CRLF3 N/A 0.191 0.173
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.166 0.098
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.033
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.166 0.225
CNTN1 CNTN1: Contactin-1 precursor 0.165 0.062
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.0688
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.165 0.030
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.0688
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.0688
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.0688
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.030
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.0688
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.0688
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.062
CNTN4 CNTN4: Contactin-4 precursor 0.165 0.062
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.0688
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.034
FN1 N/A 0.165 0.0688
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.0688
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.0688
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.062
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.0688
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.0688
BSG N/A 0.165 0.062
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.0688
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.165 0.062
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.062
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.062
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.0688
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.165 0.062
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.153 0.191
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.153 0.123
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.152 0.046
KIT KIT: Mast/stem cell growth factor receptor precursor 0.152 0.046
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.152 0.041
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 0.113
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 0.503
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.126 0.136
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.126 0.051
CD2AP CD2AP: CD2-associated protein 0.126 0.041
CRKL CRKL: Crk-like protein 0.126 0.090
RDX RDX: Radixin 0.126 0.065
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.171
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.039
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.125 0.029
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.125 0.029
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.124 0.046
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.124 0.088
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.123 0.045
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.123 0.041
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.123 0.046
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.037
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.123 0.041
INSR INSR: Insulin receptor precursor 0.123 0.046
IL9R IL9R: Interleukin-9 receptor precursor 0.123 0.041
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.123 0.057
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.123 0.041
GHR GHR: Growth hormone receptor precursor 0.123 0.045
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.123 0.045
DCC DCC: Netrin receptor DCC precursor 0.123 0.041
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.051
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.105
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.051
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.041
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.031
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.098
ELMO1 N/A 0.109 0.047
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 0.047
ARHGEF7 N/A 0.109 0.036
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.049
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.109
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.165
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.109
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.049
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.098
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.109
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.062
NF2 NF2, SCH: Merlin 0.109 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.109
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.044
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.049
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 0.109
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 0.109
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.04
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.165
STAT3 0.109 0.109
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 0.098
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.04
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.165
MAPK15 N/A 0.109 1.30
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 0.098
PSCD2 N/A 0.109 0.04
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.148
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.109
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.165
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 0.044
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.109
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.044
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.148
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.049
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.044
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.049
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 0.047
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.046
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.045
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 0.063
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.051
TNC TNC, HXB: Tenascin precursor 0.109 0.041
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.063
ITGB4 N/A 0.109 0.045
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.109 0.041
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.174
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.109 0.037
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.058
SORL1 SORL1: Sortilin-related receptor precursor 0.109 0.114
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.109 0.063
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.109 0.041
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.109 0.037
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.109 0.041
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.063
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.109 0.041
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.109 0.041
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.109 0.041
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.032
PRLR PRLR: Prolactin receptor precursor 0.109 0.041
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.109 0.041
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 0.318
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.045
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.174
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.046
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.109 0.041
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.109 0.041
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.035
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.251
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 0.148
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 0.090
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 0.274
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.041
RPS6KB1 N/A 0.100 0.225
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 0.340
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.100 0.166
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 0.372
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.033
TLN1 TLN1: Uncharacterized protein TLN1 0.100 0.181
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.139
DOK1 DOK1: Docking protein 1 0.100 0.461
PLD2 PLD2: Phospholipase D2 0.100 0.027
NEO1 NEO1, NGN: Neogenin precursor 0.098 0.036
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.037
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.098 0.037
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.098 0.046
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.098 0.037
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.098 0.041
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.098 0.037
PTPRZ1 N/A 0.098 0.041
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.051
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.098 0.063
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.045
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.098 0.046
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.046
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.098 0.046
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.096 0.046
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.091 0.098
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.091 0.225
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.091 0.097
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.098
KIR3DL1 N/A 0.083 0.0688
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.083 0.034
ATRN N/A 0.083 0.030
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 0.062
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.083 0.0688
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.083 0.0688
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.083 0.0688
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.041
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 0.090
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 0.503
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.852
TLN2 TLN2: Uncharacterized protein TLN2 0.081 0.058
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.100
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.051
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.111
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.081 0.225
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.081 0.274
HCK N/A 0.081 1.07
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.275
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.113
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.225
FGL2 FGL2: Fibroleukin precursor 0.081 0.038
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.065
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.191
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.146
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.081 0.225
SYK SYK: Tyrosine-protein kinase SYK 0.081 0.340
SORBS3 SORBS3, SCAM1: Vinexin 0.081 0.029
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.091
STK16 N/A 0.081 0.123
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.077 0.126
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.077 0.105
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.077 0.105
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.075 0.098
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.075 0.041
CDK2 CDK2: Cell division protein kinase 2 0.075 0.097
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.088
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.225
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.075 0.064
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.416
WEE1 WEE1: Wee1-like protein kinase 0.075 0.098
SPTAN1 N/A 0.0727 0.033
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 0.100
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.111
MSN MSN: Moesin 0.072 0.245
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 0.253
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 0.058
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.078
FNBP1 N/A 0.072 0.114
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 1.07
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 0.304
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.515
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 0.100
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.072 0.065
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.065
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 0.561
JAK1 0.072 0.202
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 0.126
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.072 0.037
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 0.227
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 0.148
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.029
ALK ALK: ALK tyrosine kinase receptor precursor 0.072 0.051
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 0.081
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.152
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.035
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.081
CSK CSK: Tyrosine-protein kinase CSK 0.072 0.181
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.072 0.045
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.114
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.191
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.124
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.123
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.051
CXorf9 N/A 0.072 0.372
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.191
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.072
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.515
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.072 0.058
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.072
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.125
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.124
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 0.090
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.100
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.072 0.094
TTN N/A 0.072 0.109
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.072 0.041
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.072 0.065
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.251
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.064
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.064
BMX N/A 0.072 0.065
LYN LYN: Tyrosine-protein kinase Lyn 0.072 0.561
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.132
VIL2 N/A 0.072 0.113
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.253
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.081
GAB2 N/A 0.072 0.0971
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.0688 0.047
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.148
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.072
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.026
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.073
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 0.113
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.027
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.040
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.058
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.0727
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.152
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 0.097
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.029
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.048
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.065 0.152
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.099
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.080
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.065
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.225
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.062 0.042
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.062 0.214
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.062 0.354
ASGR1 ASGR1: Asialoglycoprotein receptor 1 0.062 0.046
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.064
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.041
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.062 0.039
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.062 0.757
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.062 0.063
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.062 0.037
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.063
CDK4 CDK4: Cell division protein kinase 4 0.057 0.097
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.057 0.307
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.245
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.057 0.098
CDK6 CDK6: Cell division protein kinase 6 0.057 0.152
DYRK3 N/A 0.057 0.098
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.056 0.065
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.055 0.063
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.055 0.045
GPA33 GPA33: Cell surface A33 antigen precursor 0.055 0.051
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.055 0.214
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.055 0.128
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.055 0.051
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.055 0.045
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.055 0.214
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.055 0.173
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.055 0.045
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.055 0.045
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.055 0.041
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.055 0.051
CD69 CD69: Early activation antigen CD69 0.055 0.039
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.055 0.174
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.055 0.354
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.055 0.332
LILRB1 N/A 0.055 0.757
CD7 CD7: T-cell antigen CD7 precursor 0.055 0.063
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.055 0.354
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.055 0.128
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.055 0.046
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.055 0.128
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.055 0.041
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.055 0.214
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.051 0.046
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.051 0.553
EPB41 EPB41, E41P: Protein 4.1 0.051 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.046
FLT4 VEGFR3 long form 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 0.046
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.051 0.046
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.051
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.051
GRB10 N/A 0.051 0.051
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.051 0.046
DOK2 DOK2: Docking protein 2 0.051 0.051
NCAM1 N/A 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
TP73 TP73, P73: Tumor protein p73 0.051 0.098
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.111
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.0513 0.078
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.049 0.045
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.049 0.045
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.049 0.041
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.049 0.045
PVR PVR, PVS: Poliovirus receptor precursor 0.049 0.041
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.049 0.046
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.980
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 1.30
MAPKAPK5 N/A 0.049 0.165
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.165
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.044
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.049 0.030
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.049 0.062
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.165
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.148
PPEF1 N/A 0.049 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.980
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.148
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.049 0.0688
MAP2K5 N/A 0.049 0.109
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.165
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.165
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.148
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.148
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.165
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.165
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.165
TNN TNN: Tenascin-N precursor 0.047 0.042
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.038
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.046 0.048
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 115.00
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.372
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.100
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0453 0.275
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.109
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0453 0.307
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.0453 0.029
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.0453 0.111
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.109
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 0.416
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.191
PLEK PLEK, P47: Pleckstrin 0.045 0.132
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.171
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.045 0.191
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.0446 0.033
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.042 0.029
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.123
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.054
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.039
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.04 0.025
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.039 0.042
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.039 0.026
XRCC1 XRCC1: DNA-repair protein XRCC1 0.039 0.032
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.038 0.045
COPA COPA: Coatomer subunit alpha 0.037 0.046
CDK7 CDK7, MO15: Cell division protein kinase 7 0.037 0.111
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.037 0.251
FLII FLII, FLIL: Protein flightless-1 homolog 0.037 0.0446
CSPG2 N/A 0.037 0.757
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.037 0.123
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.037 0.372
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.037 38.50
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.109
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.225
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.037 0.416
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.037 0.066
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.098
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.515
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.037 0.041
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.027
STK10 STK10: Uncharacterized protein STK10 0.037 0.416
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.037 0.251
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.037 0.191
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.074
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.461
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.037 0.123
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.025
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.136
CFP CFP, PFC: Properdin precursor 0.037 0.042
PRG2 PRG2, MBP: Bone marrow proteoglycan precursor 0.037 0.025
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.037 0.136
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.111
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0338 0.0338
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.0338 0.053
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.148
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.148
CETN1 CETN1, CEN1, CETN: Centrin-1 0.034 0.028
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.034 0.028
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.034 0.148
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.307
LCP1 LCP1, PLS2: Plastin-2 0.032 0.111
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.097
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.152
SFTPA2 SFTPA2, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A2 precursor 0.032 0.039
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.171
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.098
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.032 0.088
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.123
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.032 0.109
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.275
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.763
PRKAA1 N/A 0.032 0.123
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.097
SFTPD SFTPD, PSPD, SFTP4: Pulmonary surfactant-associated protein D precursor 0.032 0.035
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 0.171
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.032 0.066
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.032 0.051
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.251
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.088
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.251
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.032 0.088
ATM ATM: Serine-protein kinase ATM 0.032 0.191
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.251
GMIP GMIP: GEM-interacting protein 0.032 0.066
CDKL5 N/A 0.032 0.123
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.109
MYO3A MYO3A: Myosin IIIA 0.032 0.088
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.064
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.066
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.032 0.088
CLEC3B CLEC3B, TNA: Tetranectin precursor 0.032 0.031
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.225
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.202
ACTN1 ACTN1: Alpha-actinin-1 0.032 0.0453
DAPK2 DAPK2: Death-associated protein kinase 2 0.032 0.123
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.031 0.078
TP53 TP53, P53: Cellular tumor antigen p53 0.031 0.069
CDK5 CDK5: Cell division protein kinase 5 0.029 0.123
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.171
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.111
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.655
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.029 0.109
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.781
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.099
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.029 0.046
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.110
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.0446
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.225
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.110
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.171
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.028 0.034
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.034
RIOK3 RIOK3, SUDD: Serine/threonine-protein kinase RIO3 0.027 0.0308
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.027 0.046
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.026 0.038
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.025 0.114
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.191
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.191
NUP214 N/A 0.025 0.087
ETS2 ETS2: Protein C-ets-2 0.025 0.155
GNB2L1 Lung cancer oncogene 7 0.025 0.052
0.347
Total Score 7.12