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Evidence of Interaction Between EPOR and SLA

The interaction score between EPOR and SLA is 7.40.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EPOR and SLA = 0.00

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.85E-3
Orthology N/A N/A
Domains Domains present in EPOR and SLA:
Domains in EPORDomains in SLA
IPR003961 Fibronectin, type III
IPR003528 Long hematopoietin receptor, single chain
IPR009167 Erythropoietin receptor
IPR002996 Cytkn_recept_B/G.
IPR001452 SH3
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in EPOR and SLA are listed below.

Domain 1Domain 2Chi Square
IPR002996 Cytkn_recept_B/G. IPR000980 SH2 motif 227.343
IPR003961 Fibronectin, type III IPR000980 SH2 motif 184.508
IPR003528 Long hematopoietin receptor, single chain IPR000980 SH2 motif 151.135
IPR009167 Erythropoietin receptor IPR000980 SH2 motif 38.4825
IPR003961 Fibronectin, type III IPR001452 SH3 15.104
IPR009167 Erythropoietin receptor IPR001452 SH3 4.09597
IPR003528 Long hematopoietin receptor, single chain IPR001452 SH3 3.64257
IPR002996 Cytkn_recept_B/G. IPR001452 SH3 0.0443172

The background colour of the table refers to:

  • Blue Domain is only present in EPOR
  • Yellow Domain is only present in SLA
  • Green Domain is present in both EPOR and SLA

 0.109
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: SLA

PTMResidueReference
Myristoylation 2 PubMed, HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: SLA

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between EPOR and SLA that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andSLA. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and SLA has 1253 interactors of which there are 568 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for SLA-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.037
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.541 0.064
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.340 0.077
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.253 0.034
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.251 0.0407
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.210 0.082
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.0727
CRLF3 N/A 0.191 0.228
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.166 0.098
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.152
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.166 0.251
CNTN1 CNTN1: Contactin-1 precursor 0.165 0.044
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.044
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.044
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.980
CNTN4 CNTN4: Contactin-4 precursor 0.165 0.044
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.044
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
FN1 N/A 0.165 0.044
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.044
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
BSG N/A 0.165 0.044
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.980
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.165 0.980
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.109
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.980
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.044
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.165 0.109
CAT CAT: Catalase 0.157 0.032
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.153 0.191
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.153 0.123
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.152 0.644
KIT KIT: Mast/stem cell growth factor receptor precursor 0.152 0.731
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.152 0.072
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 0.251
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 3.28
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.126 0.152
CD2AP CD2AP: CD2-associated protein 0.126 0.152
CRKL CRKL: Crk-like protein 0.126 0.191
RDX RDX: Radixin 0.126 0.110
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.064
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.123
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.125 0.032
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.124 0.098
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.123 0.026
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.123 0.065
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.123 0.902
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.654
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.123 0.581
INSR INSR: Insulin receptor precursor 0.123 0.581
IL9R IL9R: Interleukin-9 receptor precursor 0.123 0.072
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.123 0.644
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.123 0.026
GHR GHR: Growth hormone receptor precursor 0.123 0.065
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.123 0.072
DCC DCC: Netrin receptor DCC precursor 0.123 0.029
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.029
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.274
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.029
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.644
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.126
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.165
ELMO1 N/A 0.109 0.165
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 0.165
ARHGEF7 N/A 0.109 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 1.30
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.165
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.056
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.165
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.165
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.165
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.540
NF2 NF2, SCH: Merlin 0.109 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 1.30
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 1.30
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.056
STAT3 0.109 0.165
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.165
MAPK15 N/A 0.109 0.165
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 1.30
PSCD2 N/A 0.109 0.165
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 1.05
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.056
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 0.165
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.165
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.165
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.165
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.165
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 0.165
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.654
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.654
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 0.731
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.274
TNC TNC, HXB: Tenascin precursor 0.109 0.026
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.166
ITGB4 N/A 0.109 0.026
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.109 0.654
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.340
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.109 0.654
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.110
SORL1 SORL1: Sortilin-related receptor precursor 0.109 0.228
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.109 0.100
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.109 0.029
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.109 0.026
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.109 0.072
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.126
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.109 0.644
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.109 0.581
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.109 0.029
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.109
PRLR PRLR: Prolactin receptor precursor 0.109 0.065
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.109 0.026
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 2.46
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.072
F3 F3: Tissue factor precursor 0.109 0.065
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.340
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.072
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.109 0.072
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.109 0.654
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.0727
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.307
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 0.307
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 0.975
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 1.98
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.123
RPS6KB1 N/A 0.100 0.251
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 4.07
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.100 0.251
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 0.852
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.191
TLN1 TLN1: Uncharacterized protein TLN1 0.100 0.307
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.416
DOK1 DOK1: Docking protein 1 0.100 0.416
PLD2 PLD2: Phospholipase D2 0.100 0.123
NEO1 NEO1, NGN: Neogenin precursor 0.098 0.029
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.644
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.098 0.654
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.098 0.654
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.098 0.731
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.098 0.0727
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.098 0.644
PTPRZ1 N/A 0.098 0.029
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.202
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.098 0.065
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.072
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.098 0.644
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.362
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.098 0.029
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.096 0.036
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.096 0.051
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.091 0.037
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.091 0.251
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.091 0.109
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.091 0.123
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.087 0.057
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.165
KIR3DL1 N/A 0.083 0.109
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.083 0.044
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.083 0.044
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.083 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.083 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.083 0.044
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.083 0.109
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.191
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 0.416
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 0.852
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.251
TLN2 TLN2: Uncharacterized protein TLN2 0.081 0.088
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.0416
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.0416
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.081 0.307
HCK N/A 0.081 6.73
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.307
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.152
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.251
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.110
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.123
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.852
DLG2 DLG2: Disks large homolog 2 0.081 0.041
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.081 0.085
SYK SYK: Tyrosine-protein kinase SYK 0.081 3.28
SORBS3 SORBS3, SCAM1: Vinexin 0.081 0.098
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.174
STK16 N/A 0.081 0.191
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.077 0.251
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.077 0.082
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.077 0.166
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.075 0.109
CDK2 CDK2: Cell division protein kinase 2 0.075 0.123
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.109
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.251
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.075 0.0416
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.307
WEE1 WEE1: Wee1-like protein kinase 0.075 0.109
SPTAN1 N/A 0.0727 0.098
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 1.98
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.098
MSN MSN: Moesin 0.072 0.852
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 0.515
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 0.775
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.037
FNBP1 N/A 0.072 0.307
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 4.07
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 0.852
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.416
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 3.28
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.072 0.098
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.098
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 0.852
JAK1 0.072 3.28
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 0.975
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 0.852
PLD1 PLD1: Phospholipase D1 0.072 0.098
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 0.416
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.088
ALK ALK: ALK tyrosine kinase receptor precursor 0.072 0.403
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 0.859
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.123
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.033
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.110
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.251
CSK CSK: Tyrosine-protein kinase CSK 0.072 3.28
PSD TYL: TYL protein 0.072 0.109
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.416
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.416
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.416
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.109
CXorf9 N/A 0.072 0.515
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.191
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.109
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.416
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.072 0.109
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.859
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.515
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.515
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 2.42
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.123
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.072 0.105
TTN N/A 0.072 0.109
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.072 0.693
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.251
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.859
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.975
BMX N/A 0.072 0.859
LYN LYN: Tyrosine-protein kinase Lyn 0.072 4.07
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.416
VIL2 N/A 0.072 0.191
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.852
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.191
GAB2 N/A 0.072 0.307
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.109
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.0688 0.109
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.109
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.067 0.174
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.109
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.098
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.123
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 0.307
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.191
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.110
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.110
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.775
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.191
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.065 0.110
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 0.109
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.152
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.152
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.065 0.975
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.110
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.307
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.098
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.340
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.062 1.19
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.062 0.561
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.251
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.100
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.062 0.202
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.062 0.202
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.062 0.126
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.062 0.072
CD44 N/A 0.062 0.101
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.027
CDK4 CDK4: Cell division protein kinase 4 0.057 0.123
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.057 0.307
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.852
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.057 0.098
CDK6 CDK6: Cell division protein kinase 6 0.057 0.152
DYRK3 N/A 0.057 0.098
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.056 0.109
EGF EGF: Pro-epidermal growth factor precursor 0.055 0.029
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.055 0.111
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.055 0.029
GPA33 GPA33: Cell surface A33 antigen precursor 0.055 0.0407
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.055 0.082
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.055 0.111
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.055 0.036
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.055 0.081
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.055 0.051
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.055 0.202
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.055 0.067
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.055 0.072
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.055 0.100
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.055 0.026
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.055 0.029
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.055 0.561
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.055 1.19
LILRB1 N/A 0.055 0.274
CD7 CD7: T-cell antigen CD7 precursor 0.055 0.082
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.055 0.228
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.055 0.111
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.055 0.026
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.055 0.082
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.055 0.065
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.055 0.0446
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.055 0.0407
ITGB7 ITGB7: Integrin beta-7 precursor 0.055 0.027
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.055 0.228
PTPRA N/A 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.051 0.051
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.051 0.051
EPB41 EPB41, E41P: Protein 4.1 0.051 0.051
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.051
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.051 0.051
FLT4 VEGFR3 long form 0.051 1.53
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 1.53
CRK CRK: Proto-oncogene C-crk 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 0.051
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 1.53
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.051 0.617
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
GRB10 N/A 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.051 0.274
TP73 TP73, P73: Tumor protein p73 0.051 0.065
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.072
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.0513 0.0286
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.049 0.126
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.049 0.033
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.049 0.026
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.049 0.065
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.049 0.029
PVR PVR, PVS: Poliovirus receptor precursor 0.049 0.026
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.049 0.0727
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.049 0.029
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.165
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.165
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.165
MAPKAPK5 N/A 0.049 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.052
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.049 0.052
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.056
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.052
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.165
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.049 0.028
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.049 0.052
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.165
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.165
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.056
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.165
MAP2K5 N/A 0.049 0.056
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.165
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.165
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.165
CNN2 CNN2: Calponin-2 0.049 0.056
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.165
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.165
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.165
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.165
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.165
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.038
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.046 0.065
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.0453 0.152
FUBP1 N/A 0.0453 0.127
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 0.307
DAB1 DAB1: Disabled homolog 1 0.0453 0.098
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.251
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.085
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.0453 0.251
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0453 0.307
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.109
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0453 0.251
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.0453 0.032
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.0453 0.0416
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.072
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 0.561
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.126
PLEK PLEK, P47: Pleckstrin 0.045 0.274
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.166
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.045 0.202
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.0446 0.026
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.0446 0.0425
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.044 0.056
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.166
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.067
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.033
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.105
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.04 0.028
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.04 0.028
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.039 0.0446
COPA COPA: Coatomer subunit alpha 0.037 0.0425
CDK7 CDK7, MO15: Cell division protein kinase 7 0.037 0.109
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.037 0.251
FLII FLII, FLIL: Protein flightless-1 homolog 0.037 0.132
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.037 0.109
CSPG2 N/A 0.037 0.027
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.037 0.123
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.037 0.0354
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.037 0.852
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.037 0.152
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.109
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.191
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.037 0.123
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.037 0.416
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.037 0.055
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.037 0.030
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.110
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.416
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.060
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.852
STK10 STK10: Uncharacterized protein STK10 0.037 0.852
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.037 0.103
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.037 0.064
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.163
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.103
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.037 0.191
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.045
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.152
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.037 0.191
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.110
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.0338 0.059
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.109
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.109
CETN1 CETN1, CEN1, CETN: Centrin-1 0.034 0.04
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.034 0.109
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.033 0.174
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.032 0.048
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.032 0.031
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.174
LCP1 LCP1, PLS2: Plastin-2 0.032 0.163
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.140
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.037
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.191
GRLF1 N/A 0.032 0.049
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.032 0.041
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.032 0.034
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.123
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.098
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.032 0.110
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.152
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.032 0.109
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.307
DAB2 DAB2, DOC2: Disabled homolog 2 0.032 0.109
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.251
PRKAA1 N/A 0.032 0.152
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.037
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 0.251
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.032 1.81
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.191
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.109
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.191
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.032 0.049
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.032 0.033
ATM ATM: Serine-protein kinase ATM 0.032 0.307
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.152
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.0971
GMIP GMIP: GEM-interacting protein 0.032 0.917
CDKL5 N/A 0.032 0.123
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.109
MYO3A MYO3A: Myosin IIIA 0.032 0.110
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.032 0.055
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.109
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.260
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.032 0.098
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.191
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.191
ACTN1 ACTN1: Alpha-actinin-1 0.032 0.048
DAPK2 DAPK2: Death-associated protein kinase 2 0.032 0.123
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.032 0.055
MTMR3 MTMR3, KIAA0371, ZFYVE10: Myotubularin-related protein 3 0.032 0.067
MDN1 MDN1, KIAA0301: Midasin 0.030 0.026
CDK5 CDK5: Cell division protein kinase 5 0.029 0.109
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.251
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.123
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.123
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.029 0.035
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.029 0.098
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.029 0.098
CNN3 CNN3: Calponin-3 0.029 0.110
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.098
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.098
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.098
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.029 0.046
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.098
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.026
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.307
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.098
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.152
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.029 0.051
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.049
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.109
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.109
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.028 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.109
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.109
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.028 0.049
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.049
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.027 0.217
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
FGFR2 N/A 0.027 0.217
TJP1 TJP1, ZO1: Tight junction protein ZO-1 0.027 0.027
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.265
PIM1 N/A 0.027 0.0308
THOC1 THOC1, HPR1: THO complex subunit 1 0.027 0.026
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.027 0.026
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0263 0.032
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.026 0.036
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.026 0.027
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.025 0.067
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.166
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.126
NUP214 N/A 0.025 0.036
ETS2 ETS2: Protein C-ets-2 0.025 0.126
GNB2L1 Lung cancer oncogene 7 0.025 0.027
0.228
Total Score 7.40