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Evidence of Interaction Between EPOR and WAS

The interaction score between EPOR and WAS is 3.86.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EPOR and WAS = -0.00

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology N/A N/A
Domains Domains present in EPOR and WAS:
Domains in EPORDomains in WAS
IPR003961 Fibronectin, type III
IPR003528 Long hematopoietin receptor, single chain
IPR009167 Erythropoietin receptor
IPR002996 Cytkn_recept_B/G.
IPR003124 Actin-binding WH2
IPR000095 PAK-box/P21-Rho-binding
IPR011026 Wiscott-Aldrich syndrome, C-terminal
IPR000697 EVH1
IPR011993 PH_type.

The Chi square scores for co-occurrence of domains that are present in EPOR and WAS are listed below.

Domain 1Domain 2Chi Square
IPR003961 Fibronectin, type III IPR011993 PH_type. 3.27464
IPR003528 Long hematopoietin receptor, single chain IPR011993 PH_type. 0.89194
IPR002996 Cytkn_recept_B/G. IPR011993 PH_type. 0.141797

The background colour of the table refers to:

  • Blue Domain is only present in EPOR
  • Yellow Domain is only present in WAS
  • Green Domain is present in both EPOR and WAS

 0.049
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: WAS

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 291 PubMed, HPRD
Phosphorylation 291 PubMed, HPRD
Phosphorylation 483 PubMed, HPRD
Phosphorylation 484 PubMed, HPRD
Phosphoserine 482 PubMed, HPRD
Phosphoserine 483 PubMed, HPRD
Phosphotyrosine 290 HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: WAS

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD
Transitive Score

The common interactors between EPOR and WAS that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andWAS. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and WAS has 1502 interactors of which there are 622 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for WAS-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.109
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.541 0.251
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.340 0.038
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.253 0.049
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.251 0.100
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.210 0.0446
HSP90AA1 Hsp89-alpha-delta-N 0.202 0.029
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.026
CRLF3 N/A 0.191 0.541
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.166 0.111
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.111
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.166 0.372
CNTN1 CNTN1: Contactin-1 precursor 0.165 0.044
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.109
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.165 0.036
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.049
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.049
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.036
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.049
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.049
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.098
CNTN4 CNTN4: Contactin-4 precursor 0.165 0.044
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.049
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.04
FN1 N/A 0.165 0.049
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.049
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.044
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.049
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.109
BSG N/A 0.165 0.044
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.165 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.044
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.098
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.049
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.165 0.044
CAT CAT: Catalase 0.157 0.029
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.153 0.171
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.153 0.171
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.152 0.064
KIT KIT: Mast/stem cell growth factor receptor precursor 0.152 0.073
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.152 0.032
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 0.275
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 0.763
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.126 0.275
CD2AP CD2AP: CD2-associated protein 0.126 72.80
CRKL CRKL: Crk-like protein 0.126 14.60
RDX RDX: Radixin 0.126 0.044
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.171
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.062
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.125 0.038
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.124 0.038
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.124 0.111
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.123 0.033
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.123 0.026
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.123 0.064
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.065
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.123 0.058
INSR INSR: Insulin receptor precursor 0.123 0.064
IL9R IL9R: Interleukin-9 receptor precursor 0.123 0.037
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.123 0.064
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.123 0.026
GHR GHR: Growth hormone receptor precursor 0.123 0.037
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.123 0.072
DCC DCC: Netrin receptor DCC precursor 0.123 0.029
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.032
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.124
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.032
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.064
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.0818
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.075
ELMO1 N/A 0.109 0.075
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.034
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 0.025
ARHGEF7 N/A 0.109 0.075
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.148
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.075
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.165
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.062
NF2 NF2, SCH: Merlin 0.109 0.083
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.075
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 0.148
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.083
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.148
STAT3 0.109 0.148
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 7.88
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.083
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.148
MAPK15 N/A 0.109 0.165
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 7.88
PSCD2 N/A 0.109 0.083
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.148
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.148
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 39.20
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.148
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.148
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 0.025
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.0727
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.0727
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 0.113
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.057
TNC TNC, HXB: Tenascin precursor 0.109 0.029
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.091
ITGB4 N/A 0.109 0.065
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.109 0.0727
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.157
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.109 0.065
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.078
SORL1 SORL1: Sortilin-related receptor precursor 0.109 0.227
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.109 0.057
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.109 0.032
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.109 0.032
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.057
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.109 0.058
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.109 0.058
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.109 0.029
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.152
PRLR PRLR: Prolactin receptor precursor 0.109 0.029
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.109 0.026
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 0.245
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.057
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.074
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.058
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.109 0.033
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.109 0.065
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.058
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.307
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 0.372
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 5.88
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 0.461
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.136
RPS6KB1 N/A 0.100 0.372
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 1.62
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.100 0.225
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 1.62
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.114
TLN1 TLN1: Uncharacterized protein TLN1 0.100 0.188
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.385
DOK1 DOK1: Docking protein 1 0.100 0.233
PLD2 PLD2: Phospholipase D2 0.100 0.056
NEO1 NEO1, NGN: Neogenin precursor 0.098 0.052
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.058
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.098 0.065
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.098 0.065
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.098 0.058
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.098 0.026
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.098 0.058
PTPRZ1 N/A 0.098 0.029
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.057
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.098 0.026
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.057
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.098 0.064
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.052
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.098 0.029
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.096 0.074
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.096 0.148
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.091 0.111
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.091 0.275
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.091 0.026
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.091 0.136
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.148
KIR3DL1 N/A 0.083 0.049
CDH6 CDH6: Cadherin-6 precursor 0.083 0.049
DLK1 DLK1, DLK: Delta-like protein precursor 0.083 0.049
ATRN N/A 0.083 0.098
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.109
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.083 0.044
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.04
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 0.098
JAG2 JAG2: Jagged-2 precursor 0.083 0.044
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.083 0.109
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.139
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 14.60
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 4.88
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.155
TLN2 TLN2: Uncharacterized protein TLN2 0.081 0.040
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.152
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.031
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.111
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.081 0.372
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.081 1.81
HCK N/A 0.081 40.60
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.461
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.225
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.081 0.032
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.275
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.099
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.171
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.822
DLG2 DLG2: Disks large homolog 2 0.081 0.037
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.081 0.372
SYK SYK: Tyrosine-protein kinase SYK 0.081 0.763
SORBS3 SORBS3, SCAM1: Vinexin 0.081 4.67
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.852
STK16 N/A 0.081 0.191
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.077 0.372
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.077 0.0446
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.077 0.166
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.075 0.111
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.075 0.038
CDK2 CDK2: Cell division protein kinase 2 0.075 0.171
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.136
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.461
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.075 0.171
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.461
WEE1 WEE1: Wee1-like protein kinase 0.075 0.111
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.074 0.032
SPTAN1 N/A 0.0727 0.110
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 0.225
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.088
MSN MSN: Moesin 0.072 0.822
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 1.62
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 4.67
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.099
FNBP1 N/A 0.072 40.60
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 86.60
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 260.00
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.372
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 0.307
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.072 0.088
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.044
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 1.81
JAK1 0.072 0.763
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 0.191
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 4.88
PLD1 PLD1: Phospholipase D1 0.072 0.056
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 24.50
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.070
ALK ALK: ALK tyrosine kinase receptor precursor 0.072 0.046
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 0.123
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.152
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.098
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.049
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.251
CSK CSK: Tyrosine-protein kinase CSK 0.072 1.62
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.072 0.037
PSD TYL: TYL protein 0.072 0.044
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.233
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.461
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.515
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.049
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.025
CXorf9 N/A 0.072 1.62
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.416
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.062
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.852
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.072 0.0308
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.109
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.822
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.763
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 0.275
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.307
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.072 0.114
TTN N/A 0.072 0.049
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.072 0.078
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.072 0.037
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.072 0.037
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.515
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.111
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.111
BMX N/A 0.072 0.109
LYN LYN: Tyrosine-protein kinase Lyn 0.072 1.62
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.260
VIL2 N/A 0.072 0.139
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 1.81
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.152
GAB2 N/A 0.072 0.155
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.098
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.098
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.044
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.097
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.171
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 14.60
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.225
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.078
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.050
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.098
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.251
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.065 0.050
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 0.097
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.136
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.096
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.065 0.152
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.099
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.188
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.099
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.245
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.062 0.066
MEP1A MEP1A: Meprin A subunit alpha precursor 0.062 0.029
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.062 1.19
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.062 0.037
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.062 0.157
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.062 0.124
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.136
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.062 0.075
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.090
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.062 0.153
SELE SELE, ELAM1: E-selectin precursor 0.062 0.033
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.062 0.137
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.062 0.0727
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.062 0.113
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.062 0.058
CD44 N/A 0.062 0.253
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.137
CDK4 CDK4: Cell division protein kinase 4 0.057 0.171
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.057 0.461
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.763
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.057 0.109
CDK6 CDK6: Cell division protein kinase 6 0.057 0.136
DYRK3 N/A 0.057 0.088
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.056 0.111
F10 F10: Coagulation factor X precursor 0.055 0.026
EGF EGF: Pro-epidermal growth factor precursor 0.055 0.072
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.055 0.027
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.055 0.032
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.055 0.153
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.055 0.340
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.055 0.040
ITGAE ITGAE: Integrin alpha-E precursor 0.055 0.153
MEP1B MEP1B: Meprin A subunit beta precursor 0.055 0.029
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.055 0.124
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.055 0.0446
CDH5 CDH5: Cadherin-5 precursor 0.055 0.032
AREG AREG, SDGF: Amphiregulin precursor 0.055 0.037
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.055 0.081
CD69 CD69: Early activation antigen CD69 0.055 0.036
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.055 0.541
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.055 0.472
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.055 0.029
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.055 0.113
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.055 0.029
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.055 1.07
LILRB1 N/A 0.055 0.074
UMOD UMOD: Uromodulin precursor 0.055 0.032
CD7 CD7: T-cell antigen CD7 precursor 0.055 0.036
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.055 0.472
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.055 0.036
CDH2 CDH2, CDHN, NCAD: Cadherin-2 precursor 0.055 0.029
LDLR LDLR: Low-density lipoprotein receptor precursor 0.055 0.029
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.055 0.0446
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.055 0.058
NOTCH4 N/A 0.055 0.029
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.055 0.137
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.055 0.033
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.055 0.075
ITGB7 ITGB7: Integrin beta-7 precursor 0.055 0.304
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.055 0.157
GNA12 GNA12: Guanine nucleotide-binding protein alpha-12 subunit 0.052 0.041
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.051 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.051 0.046
FLT4 VEGFR3 long form 0.051 0.046
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 2.45
DLG1 DLG1: Disks large homolog 1 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.051
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.051 0.046
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.051
GRB10 N/A 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.051 0.066
ST3GAL1 ST3GAL1, SIAT4, SIAT4A: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sia 0.051 0.027
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.073
ST8SIA4 ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe 0.051 0.0446
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.0513 0.066
ITGAV ITGAV, MSK8, VNRA: Integrin alpha-V precursor 0.049 0.029
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.049 0.032
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.049 0.029
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.049 0.065
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.049 0.026
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.049 0.026
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.165
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.148
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.083
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.148
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.165
MAPKAPK5 N/A 0.049 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.083
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.049 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.049 0.075
PLAT PLAT: Tissue-type plasminogen activator precursor 0.049 0.030
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.148
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.165
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.075
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.075
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.049 0.030
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.049 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.049 0.075
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.148
PPEF1 N/A 0.049 0.083
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.165
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.148
F7 F7: Coagulation factor VII precursor 0.049 0.030
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.148
BMP1 N/A 0.049 0.030
MAP2K5 N/A 0.049 0.165
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.049 0.075
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.165
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.148
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.148
SNX3 N/A 0.049 0.047
CNN2 CNN2: Calponin-2 0.049 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.075
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.148
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.165
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.0453 0.114
FUBP1 N/A 0.0453 0.070
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 0.461
DAB1 DAB1: Disabled homolog 1 0.0453 0.044
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.461
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.191
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.0453 0.046
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0453 0.372
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.123
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0453 0.307
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.0453 0.063
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.0453 0.171
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.065
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 0.561
ST6GAL1 ST6GAL1, SIAT1: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltrans 0.045 0.032
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.166
PLEK PLEK, P47: Pleckstrin 0.045 0.541
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.181
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.045 0.245
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.0446 0.029
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.0446 0.038
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.0446 0.046
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.044 0.030
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.148
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.073
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.0513
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.04 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.04 0.075
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 0.039 0.032
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.039 0.036
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.039 0.036
XRCC1 XRCC1: DNA-repair protein XRCC1 0.039 0.027
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.038 0.036
TBCE TBCE: Tubulin-specific chaperone E 0.037 0.038
COPA COPA: Coatomer subunit alpha 0.037 0.046
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.037 0.046
CDK7 CDK7, MO15: Cell division protein kinase 7 0.037 0.171
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.037 0.307
FLII FLII, FLIL: Protein flightless-1 homolog 0.037 0.078
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.037 0.127
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.037 29.20
CSPG2 N/A 0.037 0.085
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.037 0.032
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.037 0.111
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.037 0.385
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.037 1.62
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.037 0.136
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.123
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.171
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.037 0.069
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.037 0.763
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.037 0.049
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.037 0.241
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.099
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.461
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.037 0.035
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.114
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.852
STK10 STK10: Uncharacterized protein STK10 0.037 1.62
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.037 0.461
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.037 0.416
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.260
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.372
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.037 0.191
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.045
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.136
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.037 0.225
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.088
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.0338 0.053
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.098
PTGS1 PTGS1, COX1: Prostaglandin G/H synthase 1 precursor 0.034 0.034
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.034 0.044
CETN1 CETN1, CEN1, CETN: Centrin-1 0.034 0.044
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.033 0.852
S100B S100B: Protein S100-B 0.032 0.049
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.032 0.069
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.032 0.044
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 1.81
LCP1 LCP1, PLS2: Plastin-2 0.032 43.70
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.078
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.097
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.032 0.040
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.416
MYL3 MYL3: Myosin light polypeptide 3 0.032 0.049
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.032 0.044
GRLF1 N/A 0.032 0.109
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.032 0.041
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.032 0.049
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.056
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.032 0.044
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.088
CHP CHP: Calcium-binding protein p22 0.032 0.114
S100A7 S100A7, PSOR1: Protein S100-A7 0.032 0.055
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.032 0.099
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.152
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.032 0.123
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.763
DAB2 DAB2, DOC2: Disabled homolog 2 0.032 0.049
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.275
PRKAA1 N/A 0.032 0.191
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.097
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 0.225
PMP2 PMP2: Myelin P2 protein 0.032 0.044
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.416
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.097
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.225
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.032 0.044
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.032 0.097
ATM ATM: Serine-protein kinase ATM 0.032 0.275
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.171
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.155
GMIP GMIP: GEM-interacting protein 0.032 0.822
CDKL5 N/A 0.032 0.109
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.152
MYO3A MYO3A: Myosin IIIA 0.032 0.088
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.032 0.056
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.111
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.822
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.032 0.088
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.275
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.171
ACTN1 ACTN1: Alpha-actinin-1 0.032 0.069
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.032 0.046
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.032 0.046
S100A3 S100A3, S100E: Protein S100-A3 0.032 0.049
DAPK2 DAPK2: Death-associated protein kinase 2 0.032 0.123
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.032 0.086
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.032 0.026
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.031 0.040
MDN1 MDN1, KIAA0301: Midasin 0.030 0.086
CDK5 CDK5: Cell division protein kinase 5 0.029 0.111
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.275
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.171
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.136
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.029 0.050
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.029 0.088
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.029 0.041
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.029 0.056
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.111
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.099
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.050
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.029 0.041
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.099
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.029 0.046
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.188
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.461
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.099
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.111
PCDHA2 PCDHA2: Protocadherin alpha 2 precursor 0.028 0.049
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.028 0.044
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.04
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.028 0.098
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
DRD2 DRD2: D(2) dopamine receptor 0.028 0.049
TMPRSS9 N/A 0.028 0.044
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.049
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.049
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.044
MUCDHL MUPCDH, MUCDHL, UNQ2781/PRO7168: Mucin and cadherin-like protein precursor 0.028 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.049
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.098
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
RIOK3 RIOK3, SUDD: Serine/threonine-protein kinase RIO3 0.027 0.028
PIM1 N/A 0.027 0.028
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.027 0.078
THOC1 THOC1, HPR1: THO complex subunit 1 0.027 0.038
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.027 0.038
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0263 0.070
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.026 0.066
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.026 0.074
RHO RHO, OPN2: Rhodopsin 0.026 0.032
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.026 0.181
FADD FADD, MORT1: Protein FADD 0.026 0.027
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.026 0.066
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.025 0.090
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.245
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.166
NUP214 N/A 0.025 0.036
ETS2 ETS2: Protein C-ets-2 0.025 0.046
GNB2L1 Lung cancer oncogene 7 0.025 0.0446
0.299
Total Score 3.86