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Evidence of Interaction Between EPOR and RPS6KA3

The interaction score between EPOR and RPS6KA3 is 6.52.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EPOR and RPS6KA3 = -0.08

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology N/A N/A
Domains Domains present in EPOR and RPS6KA3:
Domains in EPORDomains in RPS6KA3
IPR003961 Fibronectin, type III
IPR003528 Long hematopoietin receptor, single chain
IPR009167 Erythropoietin receptor
IPR002996 Cytkn_recept_B/G.
IPR000215 Proteinase inhibititor I4, serpin
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR000961 Protein kinase C-terminal domain

The Chi square scores for co-occurrence of domains that are present in EPOR and RPS6KA3 are listed below.

Domain 1Domain 2Chi Square
IPR003961 Fibronectin, type III IPR008271 Serine/threonine protein kinase, active site 30.5883
IPR002996 Cytkn_recept_B/G. IPR001245 Tyrosine protein kinase 15.1473
IPR003961 Fibronectin, type III IPR002290 Serine/threonine protein kinase 13.198
IPR003961 Fibronectin, type III IPR001245 Tyrosine protein kinase 6.5864
IPR003528 Long hematopoietin receptor, single chain IPR001245 Tyrosine protein kinase 5.65936
IPR003528 Long hematopoietin receptor, single chain IPR011009 Protein kinase-like 3.32619
IPR002996 Cytkn_recept_B/G. IPR002290 Serine/threonine protein kinase 2.93674
IPR003528 Long hematopoietin receptor, single chain IPR000719 Protein kinase 1.94307
IPR002996 Cytkn_recept_B/G. IPR011009 Protein kinase-like 1.93327
IPR002996 Cytkn_recept_B/G. IPR000719 Protein kinase 1.43014
IPR009167 Erythropoietin receptor IPR000719 Protein kinase 0.93762
IPR009167 Erythropoietin receptor IPR001245 Tyrosine protein kinase 0.822994
IPR003961 Fibronectin, type III IPR000719 Protein kinase 0.712801
IPR003961 Fibronectin, type III IPR011009 Protein kinase-like 0.616354
IPR009167 Erythropoietin receptor IPR011009 Protein kinase-like 0.331462

The background colour of the table refers to:

  • Blue Domain is only present in EPOR
  • Yellow Domain is only present in RPS6KA3
  • Green Domain is present in both EPOR and RPS6KA3

 0.109
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: RPS6KA3

PTMResidueReference
Phosphorylation 227 PubMed, HPRD
Phosphorylation 386 PubMed, HPRD
Phosphorylation 707 PubMed, HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: RPS6KA3

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between EPOR and RPS6KA3 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andRPS6KA3. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and RPS6KA3 has 1243 interactors of which there are 614 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for RPS6KA3-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.041
OSM OSM: Oncostatin-M precursor 1.48 0.039
IFNG IFNG: Interferon gamma precursor 0.980 0.052
KITLG KITLG, MGF, SCF: Kit ligand precursor 0.980 0.028
CSF3 CSF3, GCSF: Granulocyte colony-stimulating factor precursor 0.980 0.028
THPO THPO, MGDF: Thrombopoietin precursor 0.980 0.028
IL4 IL4: Interleukin-4 precursor 0.980 0.028
CSF2 CSF2, GMCSF: Granulocyte-macrophage colony-stimulating factor precursor 0.902 0.060
IL5 IL5: Interleukin-5 precursor 0.731 0.034
IL3 IL3: Interleukin-3 precursor 0.731 0.034
PRL PRL: Prolactin precursor 0.644 0.055
LIF LIF, HILDA: Leukemia inhibitory factor precursor 0.644 0.039
CSH2 GH1: Somatotropin precursor 0.644 0.055
IL2 IL2: Interleukin 2 0.644 0.034
IL6 IL6, IFNB2: Interleukin-6 precursor 0.644 0.039
EPO EPO: Erythropoietin precursor 0.581 0.031
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.340 0.094
KEL KEL: Kell blood group glycoprotein 0.307 0.029
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.210 0.075
HSP90AA1 Hsp89-alpha-delta-N 0.202 0.035
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.065
CRLF3 N/A 0.191 0.416
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.057
CNTN1 CNTN1: Contactin-1 precursor 0.165 0.148
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.109
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.165 0.098
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.049
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.083
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.049
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.036
CNTN4 CNTN4: Contactin-4 precursor 0.165 0.148
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.165
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
FN1 N/A 0.165 0.165
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.083
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.049
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.165
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.049
BSG N/A 0.165 0.044
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.165 0.036
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.098
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.165 0.098
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.152 0.041
KIT KIT: Mast/stem cell growth factor receptor precursor 0.152 0.041
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.152 0.081
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 7.12
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 0.114
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.126 0.110
CD2AP CD2AP: CD2-associated protein 0.126 0.155
CRKL CRKL: Crk-like protein 0.126 0.114
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.126 0.111
RDX RDX: Radixin 0.126 0.046
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.063
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.125 0.038
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.124 0.035
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.123 0.032
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.123 0.032
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.123 0.064
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.044
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.123 0.064
INSR INSR: Insulin receptor precursor 0.123 0.064
IL9R IL9R: Interleukin-9 receptor precursor 0.123 0.081
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.123 0.033
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.123 0.073
GHR GHR: Growth hormone receptor precursor 0.123 0.100
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.123 0.032
DCC DCC: Netrin receptor DCC precursor 0.123 0.073
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.109
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.166
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.032
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.064
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.062
ELMO1 N/A 0.109 0.062
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.165
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 0.062
ARHGEF7 N/A 0.109 0.062
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.0688
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.0688
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.109 0.148
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.0688
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.062
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.062
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.0688
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.148
NF2 NF2, SCH: Merlin 0.109 0.0688
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.0688
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.109 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.062
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.0688
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 0.062
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 0.030
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.0688
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.062
STAT3 0.109 0.062
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 0.062
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.109 0.148
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.0688
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.062
MAPK15 N/A 0.109 0.034
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 0.062
PSCD2 N/A 0.109 0.0688
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.062
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.0688
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 0.062
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.062
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.062
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.062
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.062
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.0688
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 0.062
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.065
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 0.051
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.166
TNC TNC, HXB: Tenascin precursor 0.109 0.111
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.166
ITGB4 N/A 0.109 0.072
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.109 0.058
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.274
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.109 0.029
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.065
SORL1 SORL1: Sortilin-related receptor precursor 0.109 0.274
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.109 0.100
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.109 0.081
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.109 0.058
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.109 0.032
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.100
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.109 0.033
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.109 0.064
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.109 0.058
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.126
PRLR PRLR: Prolactin receptor precursor 0.109 0.0727
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.109 0.088
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 0.033
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.0453
F3 F3: Tissue factor precursor 0.109 0.081
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.202
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.058
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.109 0.171
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.109 0.026
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.041
ANGPTL3 ANGPTL3, ANGPT5, UNQ153/PRO179: Angiopoietin-related protein 3 precursor 0.100 0.111
IFNW1 IFNW1: Interferon omega-1 precursor 0.100 0.034
CP CP: Ceruloplasmin precursor 0.100 0.098
FGA N/A 0.100 0.136
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.085
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 0.094
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 0.041
FGB FGB: Fibrinogen beta chain precursor [Contains: Fibrinopeptide B] 0.100 0.111
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 0.094
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.046
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 0.155
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.057
TLN1 TLN1: Uncharacterized protein TLN1 0.100 0.046
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.114
DOK1 DOK1: Docking protein 1 0.100 0.114
PLD2 PLD2: Phospholipase D2 0.100 0.057
NEO1 NEO1, NGN: Neogenin precursor 0.098 0.058
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.058
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.098 0.058
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.098 0.090
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.098 0.026
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.098 0.058
PTPRZ1 N/A 0.098 0.058
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.166
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.098 0.099
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.0453
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.098 0.090
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.029
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.098 0.065
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.096 0.036
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.096 0.033
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.091 0.057
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.091 0.051
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.087 0.033
ABCG2 ABCG2, ABCP, BCRP, BCRP1, MXR: ATP-binding cassette sub-family G member 2 0.087 0.029
KIR3DL1 N/A 0.083 0.049
DLK1 DLK1, DLK: Delta-like protein precursor 0.083 0.109
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.083 0.049
ATRN N/A 0.083 0.098
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.083 0.098
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.083 0.028
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.109
JAG2 JAG2: Jagged-2 precursor 0.083 0.098
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.083 0.049
OPTC OPTC, OPT: Opticin precursor 0.083 0.028
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.083 0.028
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.083 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.083 0.049
EDA N/A 0.083 0.049
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.083 0.083
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.083 0.109
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.114
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 0.094
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 0.155
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.063
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.063
F5 F5: Coagulation factor V precursor 0.081 0.123
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.123
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.046
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.081 0.105
HCK N/A 0.081 0.071
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.155
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.057
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.081 0.0513
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.094
FGL2 FGL2: Fibroleukin precursor 0.081 0.171
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.033
IFNA14 IFNA14: Interferon alpha-14 precursor 0.081 0.034
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.028
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.081 0.188
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.155
DLG2 DLG2: Disks large homolog 2 0.081 0.099
SYK SYK: Tyrosine-protein kinase SYK 0.081 0.114
SORBS3 SORBS3, SCAM1: Vinexin 0.081 0.041
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.0794
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.077 0.124
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.077 0.075
IL15RA IL15RA: Interleukin-15 receptor alpha chain precursor 0.075 0.191
SPTAN1 N/A 0.0727 0.041
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 0.114
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.037
MSN MSN: Moesin 0.072 0.155
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 0.155
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 0.071
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.037
FNBP1 N/A 0.072 0.155
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 0.094
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 0.155
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.057
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 0.128
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.041
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 0.128
JAK1 0.072 0.155
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 0.063
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.072 0.088
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 0.155
PLD1 PLD1: Phospholipase D1 0.072 0.071
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 0.192
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.046
ALK ALK: ALK tyrosine kinase receptor precursor 0.072 0.086
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 0.0794
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.041
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.051
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.105
CSK CSK: Tyrosine-protein kinase CSK 0.072 0.155
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.072 0.097
PSD TYL: TYL protein 0.072 0.041
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.094
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.155
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.0794
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.063
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.055
CXorf9 N/A 0.072 0.155
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.051
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.072 0.046
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.051
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.155
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.155
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 55.00
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.105
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.072 0.109
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.072 0.111
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.072 0.111
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.128
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.041
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.046
IFNB1 IFNB1, IFB, IFNB: Interferon beta precursor 0.072 0.034
BMX N/A 0.072 0.045
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.072 0.088
MFAP4 MFAP4: Microfibril-associated glycoprotein 4 precursor 0.072 0.097
LYN LYN: Tyrosine-protein kinase Lyn 0.072 0.094
LAMA2 LAMA2: Uncharacterized protein LAMA2 0.072 0.097
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.105
VIL2 N/A 0.072 0.094
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.128
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.173
GAB2 N/A 0.072 0.063
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.030
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.0688 0.062
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.062
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.037
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.046
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.057
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 0.114
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.094
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.033
F8 F8, F8C: Coagulation factor VIII precursor 0.065 0.109
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.037
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.041
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.065 0.099
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.094
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.128
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.041
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.114
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.037
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.155
MEP1A MEP1A: Meprin A subunit alpha precursor 0.062 0.064
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.062 0.091
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.062 0.072
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.062 0.210
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.062 0.166
ASGR1 ASGR1: Asialoglycoprotein receptor 1 0.062 0.033
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.067
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.062 0.100
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.033
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.062 0.037
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.062 0.057
SELE SELE, ELAM1: E-selectin precursor 0.062 0.065
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.062 0.181
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.062 0.033
CD44 N/A 0.062 0.124
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.087
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.155
F10 F10: Coagulation factor X precursor 0.055 0.770
EGF EGF: Pro-epidermal growth factor precursor 0.055 0.072
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.055 0.124
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.055 0.055
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.055 0.859
GPA33 GPA33: Cell surface A33 antigen precursor 0.055 0.0453
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.055 0.127
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.055 0.091
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.055 0.100
ITGAE ITGAE: Integrin alpha-E precursor 0.055 0.027
MEP1B MEP1B: Meprin A subunit beta precursor 0.055 0.073
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.055 0.049
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.055 0.057
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.055 0.127
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.055 0.0453
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.055 0.075
AREG AREG, SDGF: Amphiregulin precursor 0.055 0.081
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.055 0.033
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.055 0.0453
CD69 CD69: Early activation antigen CD69 0.055 0.124
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.055 0.202
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.055 0.260
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.055 0.072
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.055 0.073
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.055 0.097
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.055 0.181
LILRB1 N/A 0.055 0.075
UMOD UMOD: Uromodulin precursor 0.055 0.109
CD7 CD7: T-cell antigen CD7 precursor 0.055 0.091
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.055 0.210
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.055 0.077
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.055 0.032
LDLR LDLR: Low-density lipoprotein receptor precursor 0.055 0.073
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.055 0.127
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.055 0.058
NOTCH4 N/A 0.055 0.088
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.055 0.148
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.055 0.064
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.055 0.126
ITGB7 ITGB7: Integrin beta-7 precursor 0.055 0.304
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.055 0.260
GNA12 GNA12: Guanine nucleotide-binding protein alpha-12 subunit 0.052 0.041
PTPRA N/A 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
RAPH1 N/A 0.051 0.051
ITIH3 ITIH3: Inter-alpha-trypsin inhibitor heavy chain H3 precursor 0.051 0.051
C9orf88 N/A 0.051 0.051
EPB41 EPB41, E41P: Protein 4.1 0.051 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.051 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.051 0.046
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 0.046
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.051 0.046
DLG1 DLG1: Disks large homolog 1 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.051 0.046
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.051
GRB10 N/A 0.051 0.051
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.051 0.046
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.051 0.046
NCAM1 N/A 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.051 0.094
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.046
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.0513 0.155
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.049 0.099
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.049 0.075
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.049 0.0453
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.049 0.0453
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.049 0.029
PVR PVR, PVS: Poliovirus receptor precursor 0.049 0.029
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.049 0.058
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.049 0.056
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.034
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.0688
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.034
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.034
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.049 0.030
PLAT PLAT: Tissue-type plasminogen activator precursor 0.049 1.17
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.062
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.030
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.049 0.075
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.034
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.030
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.049 0.148
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.049 0.030
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.049 0.030
DCN DCN: Decorin precursor 0.049 0.028
PPEF1 N/A 0.049 0.034
CD46 N/A 0.049 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.034
F7 F7: Coagulation factor VII precursor 0.049 1.17
C4A C4A: Complement C4-A precursor 0.049 0.028
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.049 0.083
BMP1 N/A 0.049 0.148
MAP2K5 N/A 0.049 0.0688
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.049 0.030
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.062
SNX3 N/A 0.049 0.062
CNN2 CNN2: Calponin-2 0.049 0.0688
CFHR1 CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2: Complement factor H-relate 0.049 0.165
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 1.64
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.030
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.062
TSHR N/A 0.048 0.033
TNN TNN: Tenascin-N precursor 0.047 0.042
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.030
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.046 0.041
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.0453 0.094
FUBP1 N/A 0.0453 0.105
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 0.056
F13B F13B: Coagulation factor XIII B chain precursor 0.0453 0.109
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.0453 0.049
DAB1 DAB1: Disabled homolog 1 0.0453 0.037
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.056
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.031
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.0453 0.192
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.025
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.051
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 0.173
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.0794
PLEK PLEK, P47: Pleckstrin 0.045 0.173
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.155
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.045 0.192
EFNA1 EFNA1, EPLG1, LERK1, TNFAIP4: Ephrin-A1 precursor 0.044 0.050
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.044 0.050
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.114
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.094
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.041
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.051
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.04 0.030
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.039 0.057
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.039 0.026
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.038 0.042
TACSTD1 TACSTD1, GA733-2, M1S2, M4S1, MIC18, TROP1: Tumor-associated calcium signal tran 0.037 0.026
C1QA C1QA: Complement C1q subcomponent subunit A precursor 0.037 0.049
C8B C8B: Complement component C8 beta chain precursor 0.037 0.097
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.037 0.859
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.037 0.039
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.037 0.041
CSPG2 N/A 0.037 0.152
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.037 0.0513
APOH APOH, B2G1: Beta-2-glycoprotein 1 precursor 0.037 0.123
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.037 0.123
MUC2 MUC2, SMUC: Mucin-2 precursor 0.037 0.123
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.037 0.076
CFB CFB, BF, BFD: Complement factor B precursor 0.037 0.859
C4BPB C4BPB: C4b-binding protein beta chain precursor 0.037 0.123
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.037 10.80
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.028
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.037 0.114
PROC PROC: Vitamin K-dependent protein C precursor 0.037 0.770
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.037 0.114
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.037 0.056
CFHR2 CFHR2, CFHL2, FHR2, HFL3: Complement factor H-related protein 2 precursor 0.037 0.123
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.046
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.105
C2 C2: Complement C2 precursor 0.037 0.859
HP HP: Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta c 0.037 0.859
F9 F9: Coagulation factor IX precursor 0.037 0.874
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.031
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.094
C8A C8A: Complement component C8 alpha chain precursor 0.037 0.109
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.034
CFP CFP, PFC: Properdin precursor 0.037 0.032
PRG2 PRG2, MBP: Bone marrow proteoglycan precursor 0.037 0.049
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.034 0.032
PTGS1 PTGS1, COX1: Prostaglandin G/H synthase 1 precursor 0.034 0.0688
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.030
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.034 0.030
CETN1 CETN1, CEN1, CETN: Centrin-1 0.034 0.030
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.033 0.037
NDP NDP: Norrin precursor 0.033 0.088
COL4A1 N/A 0.032 0.111
C6 C6: Complement component C6 precursor 0.032 0.097
THBS1 THBS1, TSP, TSP1: Thrombospondin-1 precursor 0.032 0.111
COL15A1 COL15A1: Collagen alpha-1(XV) chain precursor [Contains: Endostatin 0.032 0.049
C7 C7: Complement component C7 precursor 0.032 0.097
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.105
LCP1 LCP1, PLS2: Plastin-2 0.032 0.076
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.114
PCOLCE PCOLCE, PCPE1: Procollagen C-endopeptidase enhancer 1 precursor 0.032 0.109
F12 F12: Coagulation factor XII precursor 0.032 0.859
COL5A2 N/A 0.032 0.062
C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 0.032 0.097
C4BPA C4BPA, C4BP: C4b-binding protein alpha chain precursor 0.032 0.109
VWF VWF, F8VWF: von Willebrand factor precursor 0.032 0.088
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.085
REG3A REG3A, HIP, PAP, PAP1: Regenerating islet-derived protein 3 alpha precursor 0.032 0.062
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.032 0.034
SFTPA2 SFTPA2, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A2 precursor 0.032 0.055
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.041
CFH CFH, HF, HF1, HF2: Complement factor H precursor 0.032 0.109
CHP CHP: Calcium-binding protein p22 0.032 0.035
LGALS1 LGALS1: Galectin-1 0.032 0.026
C1S C1S: Complement C1s subcomponent precursor 0.032 0.859
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.056
DAB2 DAB2, DOC2: Disabled homolog 2 0.032 0.041
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.071
SFTPD SFTPD, PSPD, SFTP4: Pulmonary surfactant-associated protein D precursor 0.032 0.049
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 0.046
COL17A1 COL17A1, BP180, BPAG2: Collagen alpha-1(XVII) chain 0.032 0.062
ADIPOQ ADIPOQ, ACDC, ACRP30, APM1, GBP28: Adiponectin precursor 0.032 0.062
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.032 0.114
COL5A1 N/A 0.032 0.062
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.032 0.062
SPARC SPARC, ON: SPARC precursor 0.032 0.049
ATM ATM: Serine-protein kinase ATM 0.032 0.094
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.031
GMIP GMIP: GEM-interacting protein 0.032 0.056
C1R C1R: Complement C1r subcomponent precursor 0.032 0.859
REG1B REG1A, PSPS, REG: Lithostathine 1 alpha precursor 0.032 0.062
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.094
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.155
COL1A1 COL1A1: Collagen alpha-1(I) chain precursor 0.032 0.062
CLEC3B CLEC3B, TNA: Tetranectin precursor 0.032 0.049
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.028
ACTN1 ACTN1: Alpha-actinin-1 0.032 0.035
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.032 0.034
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.032 0.031
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.032 0.062
GPR23 LPA4, GPR23, P2RY9: Lysophosphatidic acid receptor 4 0.032 0.032
COL16A1 COL16A1: Collagen alpha-1(XVI) chain precursor 0.029 0.062
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.046
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.035
IL2RA IL2RA: Interleukin-2 receptor alpha chain precursor 0.029 0.098
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.029 0.097
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.029 0.046
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.029 0.055
CNN3 CNN3: Calponin-3 0.029 0.041
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.037
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.029 0.088
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.029 0.031
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.155
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.076
SLIT2 SLIT2, SLIL3: Slit homolog 2 protein precursor 0.029 0.088
AQP4 AQP4: Aquaporin-4 0.028 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.044
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.028 1.17
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.028 0.098
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.109
TBXA2R TBXA2R: Thromboxane A2 receptor 0.028 0.049
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.028 0.044
DRD2 DRD2: D(2) dopamine receptor 0.028 0.049
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.028 0.04
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.028 0.049
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.028 0.028
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.028 0.049
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.028 0.049
TMPRSS9 N/A 0.028 0.878
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.028 0.049
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.109
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.028 0.044
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.028 0.049
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.109
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.098
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.049
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.028 0.049
GPRC5A GPRC5A, GPCR5A, RAI3, RAIG1: Retinoic acid-induced protein 3 0.028 0.049
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.109
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.044
ROBO1 N/A 0.027 0.027
CRLF1 CRLF1, ZCYTOR5, UNQ288/PRO327: Cytokine receptor-like factor 1 precursor 0.027 0.027
IL5RA N/A 0.027 0.027
NTN4 NTN4: Netrin-4 precursor 0.027 0.027
IL22RA2 IL22RA2, UNQ5793/PRO19598/PRO19822: Interleukin-22 receptor alpha-2 chain precur 0.027 0.027
TRIM42 TRIM42: Tripartite motif-containing protein 42 0.027 0.027
PTPRT PTPRT, KIAA0283: Receptor-type tyrosine-protein phosphatase T precursor 0.027 0.027
THOC1 THOC1, HPR1: THO complex subunit 1 0.027 0.114
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0263 0.0513
F2RL3 F2RL3, PAR4: Proteinase-activated receptor 4 precursor 0.026 0.032
SLC2A2 SLC2A2, GLUT2: Solute carrier family 2, facilitated glucose transporter member 2 0.026 0.033
SSTR3 SSTR3: Somatostatin receptor type 3 0.026 0.029
RHO RHO, OPN2: Rhodopsin 0.026 0.0727
FADD FADD, MORT1: Protein FADD 0.026 0.127
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.026 0.032
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.025 0.046
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.076
ETS2 ETS2: Protein C-ets-2 0.025 0.031
0.228
Total Score 6.52