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Evidence of Interaction Between EPOR and WASPIP

The interaction score between EPOR and WASPIP is 1.12.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EPOR and WASPIP = -0.06

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology N/A N/A
Domains No domains were used in calculating likelihood of interaction 0.014
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: WASPIP

PTMResidueReference
Phosphorylation 488 PubMed, HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: WASPIP

LocalisationReference
Cytoplasm HPRD
Transitive Score

The common interactors between EPOR and WASPIP that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andWASPIP. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and WASPIP has 1007 interactors of which there are 438 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for WASPIP-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.109
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.541 0.026
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.340 0.038
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.251 0.037
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.210 0.036
HSP90AA1 Hsp89-alpha-delta-N 0.202 0.029
CRLF3 N/A 0.191 0.157
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.166 0.062
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.111
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.166 0.188
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.049
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.044
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.049
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.049
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.049
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.165 0.044
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.044
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.153 0.086
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.153 0.038
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.152 0.029
KIT KIT: Mast/stem cell growth factor receptor precursor 0.152 0.029
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 0.139
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 0.372
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.126 0.139
CD2AP CD2AP: CD2-associated protein 0.126 0.275
CRKL CRKL: Crk-like protein 0.126 14.60
RDX RDX: Radixin 0.126 0.044
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.086
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.062
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.125 0.038
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.124 0.038
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.124 0.056
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.123 0.029
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.029
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.123 0.026
INSR INSR: Insulin receptor precursor 0.123 0.026
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.123 0.029
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.027
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.026
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.027
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.075
ELMO1 N/A 0.109 0.075
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 0.025
ARHGEF7 N/A 0.109 0.075
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.075
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.075
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.165
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.030
NF2 NF2, SCH: Merlin 0.109 0.083
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.075
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 0.165
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 0.075
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.083
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.165
STAT3 0.109 0.148
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 7.88
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.083
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.075
MAPK15 N/A 0.109 0.083
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 7.88
PSCD2 N/A 0.109 0.083
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.075
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.075
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.165
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.075
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.165
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.148
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 0.025
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.033
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.033
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 0.041
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.027
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.036
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.109 0.033
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.074
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.109 0.029
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.040
SORL1 SORL1: Sortilin-related receptor precursor 0.109 0.141
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.109 0.029
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.109 0.026
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.191
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 0.067
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.0446
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.026
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.109 0.029
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.058
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.210
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 0.275
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 5.18
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 0.416
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.136
RPS6KB1 N/A 0.100 0.233
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 0.852
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.100 0.114
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 0.822
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.139
TLN1 TLN1: Uncharacterized protein TLN1 0.100 0.046
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.129
DOK1 DOK1: Docking protein 1 0.100 0.188
PLD2 PLD2: Phospholipase D2 0.100 0.056
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.026
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.098 0.026
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.098 0.026
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.098 0.029
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.098 0.026
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.027
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.098 0.029
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.026
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.096 0.074
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.091 0.139
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.091 0.026
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.091 0.086
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.075
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.139
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 19.80
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 1.62
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.077
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.152
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.136
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.081 0.233
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.081 0.515
HCK N/A 0.081 19.80
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.233
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.114
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.081 0.0425
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.139
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.099
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.069
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.385
DLG2 DLG2: Disks large homolog 2 0.081 0.041
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.081 0.139
SYK SYK: Tyrosine-protein kinase SYK 0.081 0.416
SORBS3 SORBS3, SCAM1: Vinexin 0.081 0.088
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.515
STK16 N/A 0.081 0.127
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.077 0.087
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.077 0.0446
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.075 0.038
CDK2 CDK2: Cell division protein kinase 2 0.075 0.086
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.086
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.233
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.075 0.029
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.063
WEE1 WEE1: Wee1-like protein kinase 0.075 0.077
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.074 0.0425
SPTAN1 N/A 0.0727 0.098
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 0.515
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.088
MSN MSN: Moesin 0.072 0.822
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 0.763
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 4.67
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.088
FNBP1 N/A 0.072 0.763
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 24.50
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 86.60
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.251
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 0.515
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.072 0.049
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.049
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 0.515
JAK1 0.072 1.81
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 0.152
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 1.62
PLD1 PLD1: Phospholipase D1 0.072 0.069
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 86.60
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.078
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 0.123
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.062
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.109
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.055
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.416
CSK CSK: Tyrosine-protein kinase CSK 0.072 1.62
PSD TYL: TYL protein 0.072 0.049
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.078
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.385
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.416
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.049
CXorf9 N/A 0.072 1.62
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.210
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.062
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.430
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.109
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.385
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.461
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 0.461
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.251
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.072 0.094
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.072 0.050
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.260
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.111
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.136
BMX N/A 0.072 0.109
LYN LYN: Tyrosine-protein kinase Lyn 0.072 0.461
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.210
VIL2 N/A 0.072 0.139
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.852
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.307
GAB2 N/A 0.072 0.096
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.044
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.098
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.044
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.111
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.225
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 19.80
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.372
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.078
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.050
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.109
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.127
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.065 0.050
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 0.056
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.225
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.127
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.065 0.077
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.050
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.233
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.044
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.304
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.062 0.027
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.062 0.157
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.062 0.157
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.062 0.027
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.046
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.051
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.062 0.032
CD44 N/A 0.062 0.036
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.040
CDK4 CDK4: Cell division protein kinase 4 0.057 0.086
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.057 0.233
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.385
CDK6 CDK6: Cell division protein kinase 6 0.057 0.062
DYRK3 N/A 0.057 0.044
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.055 0.0446
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.055 0.027
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.055 0.074
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.055 0.066
ITGAE ITGAE: Integrin alpha-E precursor 0.055 0.036
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.055 0.027
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.055 0.027
CD69 CD69: Early activation antigen CD69 0.055 0.0446
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.055 0.074
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.055 0.157
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.055 0.066
LILRB1 N/A 0.055 0.027
CD7 CD7: T-cell antigen CD7 precursor 0.055 0.0446
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.055 0.157
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.055 0.027
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.055 0.036
ITGB7 ITGB7: Integrin beta-7 precursor 0.055 0.141
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.055 0.157
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.051 0.046
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 2.45
DLG1 DLG1: Disks large homolog 1 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.051 0.046
GRB10 N/A 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
ST3GAL1 ST3GAL1, SIAT4, SIAT4A: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sia 0.051 0.036
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.073
ST8SIA4 ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe 0.051 0.0446
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.0513 0.040
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.028
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.075
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.025
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.028
MAPKAPK5 N/A 0.049 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.028
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.049 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.049 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.075
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.028
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.025
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.028
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.049 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.049 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.025
PPEF1 N/A 0.049 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.028
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.025
MAP2K5 N/A 0.049 0.083
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.025
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.049 0.025
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.028
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.025
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.083
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.025
SNX3 N/A 0.049 0.025
CNN2 CNN2: Calponin-2 0.049 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.075
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.025
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.028
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.0453 0.086
FUBP1 N/A 0.0453 0.087
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 0.233
DAB1 DAB1: Disabled homolog 1 0.0453 0.044
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.046
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.032
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.0453 0.078
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0453 0.046
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.077
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0453 0.052
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.0453 0.063
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.065
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 1.19
ST6GAL1 ST6GAL1, SIAT1: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltrans 0.045 0.040
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.166
PLEK PLEK, P47: Pleckstrin 0.045 0.253
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.245
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.045 0.503
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.0446 0.038
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.0446 0.046
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.245
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.081
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.039
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.04 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.04 0.025
XRCC1 XRCC1: DNA-repair protein XRCC1 0.039 0.027
TBCE TBCE: Tubulin-specific chaperone E 0.037 0.038
COPA COPA: Coatomer subunit alpha 0.037 0.046
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.037 0.046
CDK7 CDK7, MO15: Cell division protein kinase 7 0.037 0.114
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.037 0.052
FLII FLII, FLIL: Protein flightless-1 homolog 0.037 0.063
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.037 0.032
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.037 148.00
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.037 0.032
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.037 0.069
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.037 0.276
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.037 0.822
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.037 0.056
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.062
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.069
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.037 0.086
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.037 0.129
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.037 0.063
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.056
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.139
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.046
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.515
STK10 STK10: Uncharacterized protein STK10 0.037 2.46
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.037 0.087
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.037 0.087
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.0425
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.038
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.037 0.052
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.069
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.037 0.046
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.088
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.036 0.029
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.036 0.026
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.044
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.033 0.287
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.032 0.029
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.917
LCP1 LCP1, PLS2: Plastin-2 0.032 0.276
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.063
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.049
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.087
GRLF1 N/A 0.032 0.055
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.049
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.049
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.026
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.032 0.062
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.233
DAB2 DAB2, DOC2: Disabled homolog 2 0.032 0.049
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.086
PRKAA1 N/A 0.032 0.096
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.056
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 0.139
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.032 431.00
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.052
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.049
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.029
ATM ATM: Serine-protein kinase ATM 0.032 0.385
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.056
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.0425
GMIP GMIP: GEM-interacting protein 0.032 0.385
CDKL5 N/A 0.032 0.055
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.096
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.056
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.129
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.032 0.044
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.139
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.056
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.032 0.032
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.031 0.032
MDN1 MDN1, KIAA0301: Midasin 0.030 0.063
CDK5 CDK5: Cell division protein kinase 5 0.029 0.056
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.139
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.086
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.086
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.069
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.050
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.050
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.099
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.063
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.385
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.099
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.027 0.078
THOC1 THOC1, HPR1: THO complex subunit 1 0.027 0.038
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.027 0.038
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0263 0.052
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.026 0.032
FADD FADD, MORT1: Protein FADD 0.026 0.027
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.026 0.040
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.040
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.075
GNB2L1 Lung cancer oncogene 7 0.025 0.0446
0.299
Total Score 1.12