PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between LIG1 and HDAC2

The interaction score between LIG1 and HDAC2 is 10.80.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between LIG1 and HDAC2 = 0.63

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

7.78E-3

Orthology

Organism	LIG1 Orthologue		HDAC2 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
bakers yeast	YDL164C	1	YNL330C	1
worm	Q27474	1	O17695	0.648
fly	Q960P4	1	Q94517	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

No domains were used in calculating likelihood of interaction

0.028

Post-translational Modifications

Protein: LIG1

PTM	Residue	Reference
Phosphorylation	66	PubMed, HPRD
Phosphorylation	76	PubMed, HPRD
Phosphorylation	141	PubMed, HPRD
Phosphorylation	195	PubMed, HPRD
Phosphorylation	911	PubMed, HPRD
Phosphoserine	66	HPRD
Phosphoserine	76	HPRD
Phosphoserine	141	HPRD
Phosphoserine	911	HPRD
Phosphothreonine	195	HPRD

Protein: HDAC2

PTM	Residue	Reference
Phosphorylation	394	PubMed, HPRD
Phosphorylation	422	PubMed, HPRD
Phosphorylation	424	PubMed, HPRD

Localisation

Protein: LIG1

Localisation	Reference
Nucleus	HPRD
Nucleoplasm	HPRD

Protein: HDAC2

Localisation	Reference
Nucleus	HPRD
Nucleolus	HPRD

Transitive Score

The common interactors between LIG1 and HDAC2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between LIG1 andHDAC2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , LIG1 has 892 interactors and HDAC2 has 1105 interactors of which there are 735 common interactors.

Common Interactor	Name of Common Interactor	Score for LIG1-Interactor (?)	Score for HDAC2-Interactor (?)
PCNA	PCNA: Proliferating cell nuclear antigen	73.00	0.078
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.704	0.471
ESPL1	N/A	0.307	0.070
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.307	0.260
DNMT1	DNMT1, AIM, DNMT: DNA	0.307	0.515
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.307	0.144
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.307	0.144
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.307	0.087
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.307	0.087
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.276	0.129
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.276	0.129
KIF11	N/A	0.276	0.063
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.276	0.078
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.276	0.063
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.276	0.078
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.276	0.078
MCM3	MCM3: DNA replication licensing factor MCM3	0.276	0.146
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.276	0.129
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.276	0.129
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.129
CBX3	CBX3: Chromobox protein homolog 3	0.276	1.62
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.276	0.461
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.251	0.070
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.191	0.0425
TCOF1	N/A	0.144	0.070
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.144	0.070
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.087
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.144	0.052
MKI67	MKI67: Antigen KI-67	0.144	0.070
SET	SET: Protein SET	0.144	0.087
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.144	0.416
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.144	0.210
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.144	0.210
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.144	0.070
UBAP2	N/A	0.144	0.087
RBM14	RBM14, SIP: RNA-binding protein 14	0.144	0.087
CENPA	CENPA: Histone H3-like centromeric protein A	0.144	0.070
PTMA	N/A	0.144	0.087
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.144	0.087
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.141	0.066
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.141	0.040
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.139	0.038
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.139	0.029
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.129	0.188
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.129	0.078
SSB	SSB: Lupus La protein	0.129	0.276
MYBL2	MYBL2, BMYB: Myb-related protein B	0.129	0.275
CDK4	CDK4: Cell division protein kinase 4	0.129	0.078
TIAL1	TIAL1: Nucleolysin TIAR	0.129	0.129
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.129	0.139
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.129	0.078
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	0.078
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.129	0.129
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.129	0.385
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.129	0.188
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.129	0.078
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.129	0.129
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.129	0.118
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.129	0.188
CDK2	CDK2: Cell division protein kinase 2	0.129	0.078
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.129
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.129	0.233
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.129	0.078
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.129	0.063
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.129	0.129
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.129	0.129
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.129	0.129
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.129	0.078
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.129
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.129
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.129	0.129
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.129	0.063
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.129	0.078
WEE1	WEE1: Wee1-like protein kinase	0.129	0.063
NOL1	N/A	0.129	0.078
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.129	0.385
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.129
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.129
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.129	0.078
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.129	0.078
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.129	0.129
CCNB1	Cyclin B1	0.129	0.233
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.129	0.078
H2AFX	H2AFX, H2AX: Histone H2A.x	0.129	0.063
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.129	0.233
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.129	0.063
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.129	0.078
CDC20	CDC20: Cell division cycle protein 20 homolog	0.129	0.233
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.129	0.372
POLA2	POLA2: DNA polymerase subunit alpha B	0.129	0.063
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.129	0.129
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.129	0.276
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.129
UNG	N/A	0.129	0.078
NUP153	N/A	0.129	0.129
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.078
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.233
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.063
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.129	0.129
ROCK1	ROCK1: Rho-associated protein kinase 1	0.127	0.052
PLEK	PLEK, P47: Pleckstrin	0.127	0.052
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.114	0.038
SOS1	SOS1: Son of sevenless homolog 1	0.114	0.029
CD2AP	CD2AP: CD2-associated protein	0.112	0.040
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.097	0.049
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.091	0.027
CRKL	CRKL: Crk-like protein	0.090	0.032
MATR3	MATR3, KIAA0723: Matrin-3	0.087	0.515
NBN	NBN, NBS, NBS1, P95: Nibrin	0.087	0.260
ABCF1	N/A	0.087	0.070
KIF23	N/A	0.087	0.070
RB1	RB1: Retinoblastoma-associated protein	0.087	0.260
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.087	0.260
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.087	0.087
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.087	0.144
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.087	0.052
DDX21	DDX21: Nucleolar RNA helicase 2	0.087	0.430
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.087	0.144
TRRAP	N/A	0.087	0.052
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.087	0.052
GNB2L1	Lung cancer oncogene 7	0.087	0.210
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.070
TOP2B	N/A	0.087	0.087
FNBP1	N/A	0.087	0.046
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.086	0.114
DOK1	DOK1: Docking protein 1	0.086	0.038
NF2	NF2, SCH: Merlin	0.083	0.028
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.078	0.275
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.078	0.078
MTA1	MTA1: Metastasis-associated protein MTA1	0.078	0.461
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.078	0.233
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.078	0.461
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.078	0.078
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.078	0.078
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.078	0.233
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.078	0.188
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.078	0.078
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.063
WBSCR20A	N/A	0.078	0.046
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.078	0.233
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.078
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.078	0.078
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.078
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.129
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.078	0.188
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.078	0.461
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.078	0.063
TP53	TP53, P53: Cellular tumor antigen p53	0.078	0.063
PHF10	N/A	0.078	0.188
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.129
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.078	0.063
PPP1R8	N/A	0.078	0.078
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.233
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.078	0.063
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.078	0.078
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.078
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.078	0.046
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.078
YY1	YY1: Transcriptional repressor protein YY1	0.078	0.461
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.078	0.188
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	0.063
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.078	102.00
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.078	0.078
MDN1	MDN1, KIAA0301: Midasin	0.078	0.118
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.078	0.233
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.078
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.063
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.078	0.078
PLEKHA5	PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member	0.077	0.026
SCRIB	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4	0.075	0.027
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.075	0.025
ELMO1	N/A	0.075	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.075	0.025
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.074	0.036
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.0446
FUBP1	N/A	0.074	0.0446
CXorf9	N/A	0.071	0.086
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.070	0.087
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.070	0.070
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.0425
KIAA0853	N/A	0.070	0.070
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.070	0.032
CHUK	N/A	0.070	0.070
SREBF2	N/A	0.070	0.070
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.070	0.307
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.070	0.052
ELF1	ELF1: ETS-related transcription factor Elf-1	0.070	0.052
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.070	0.087
RBM6	RBM6, DEF3: RNA-binding protein 6	0.070	0.0425
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.070
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.070
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.070	0.070
ARFGAP1	N/A	0.070	0.052
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.070	0.052
API5	N/A	0.070	0.087
IRF3	IRF3: Interferon regulatory factor 3	0.070	0.0425
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.070	0.251
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.087
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.070	0.210
MYB	MYB: Myb proto-oncogene protein	0.070	0.307
TGIF2	TGIF2: Homeobox protein TGIF2	0.070	0.052
XPO1	XPO1, CRM1: Exportin-1	0.066	0.066
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.066	0.090
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.066	0.032
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.066
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.066	0.066
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.066	0.040
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.066
HSPD1		0.066	0.040
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.066	0.040
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.066	0.066
TK1	TK1: Thymidine kinase, cytosolic	0.066	0.032
LDHB	LDHB: L-lactate dehydrogenase B chain	0.066	0.040
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.040
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.066	0.032
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.066	0.141
CTPS	CTPS: CTP synthase 1	0.066	0.040
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.066	0.040
CDC23	CDC23: Cell division cycle protein 23 homolog	0.066	0.066
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.141
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.063	0.046
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.063
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.063	0.063
CUL5	CUL5, VACM1: Cullin-5	0.063	0.063
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.063	0.038
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.063	0.114
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.063	0.038
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.078
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.078
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.063	0.063
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.063	0.063
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.233
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.063	0.139
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.063	0.078
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.063	0.038
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.046
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.063	0.188
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.063	0.275
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.063	0.063
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.063	0.139
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.078
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.372
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.275
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.063	0.275
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.063	0.233
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.063	0.046
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.063	0.063
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.046
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.063	0.063
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.063	0.078
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.063	0.139
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.063	0.078
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.063	0.046
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.063	0.078
SAPS3	N/A	0.063	0.046
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.046
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.063
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.062	0.032
GAB1	GAB1: GRB2-associated-binding protein 1	0.062	0.026
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.052	0.052
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.052	0.251
HIVEP1	N/A	0.052	0.307
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.052	0.087
AFF1	N/A	0.052	0.0425
NCOA3	N/A	0.052	0.052
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.052	0.087
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.052	0.070
IFI16	N/A	0.052	0.052
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.052	0.032
SMARCC2	N/A	0.052	0.0425
SP100	N/A	0.052	0.052
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.052	0.052
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.052	0.0425
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.052	0.155
XRCC1	XRCC1: DNA-repair protein XRCC1	0.052	0.210
EMD	EMD, EDMD, STA: Emerin	0.052	0.0425
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.307
EZH2	EZH2: Enhancer of zeste homolog 2	0.0479	0.143
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.047	0.025
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.046
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.046	0.078
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.046	0.046
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.046	0.063
SYMPK	SYMPK, SPK: Symplekin	0.046	0.046
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.046	0.114
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.046	0.038
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.046	0.038
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.046	0.046
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.046	0.139
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.046	0.046
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.046	0.046
SRF	SRF: Serum response factor	0.046	0.372
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.046	0.038
EP300	N/A	0.046	0.063
COPB2	COPB2: Coatomer subunit beta'	0.046	0.233
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.046	0.233
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.046	0.038
CDK7	CDK7, MO15: Cell division protein kinase 7	0.046	0.078
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.046	0.114
WDR79	N/A	0.046	0.038
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.046	0.029
SP3	SP3: Transcription factor Sp3	0.046	0.372
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.046	0.078
CSDA	CSDA, DBPA: DNA-binding protein A	0.046	0.046
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.046	0.225
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.046	0.046
KIAA1012	KIAA1012: Protein TRS85 homolog	0.046	0.063
DIAPH1	Diaphanous 1	0.046	0.038
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.046	0.046
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.046	0.063
RPS6KB1	N/A	0.046	0.063
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.046	0.038
RUNX1	N/A	0.046	0.038
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.046	0.046
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.046
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.046	0.275
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.046	0.087
TOP3A	TOP3A, TOP3: DNA topoisomerase 3-alpha	0.046	0.038
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.063
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.046	72.80
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.046	0.078
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.046	0.078
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.046	0.029
KLHDC4	N/A	0.046	0.046
RBM7		0.046	0.063
ARMET	ARMET, ARP: Protein ARMET precursor	0.046	0.046
CUL4B	N/A	0.046	0.046
FKBP4	FKBP4: FK506-binding protein 4	0.046	0.046
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.046	0.046
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.046	0.225
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.046	0.063
TAL1	TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1	0.046	0.038
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.046	0.171
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.036
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.0446	0.036
PHB2	PHB2, BAP, REA: Prohibitin-2	0.0446	0.036
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.0446	0.0446
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.0425	0.032
GTF2F2	N/A	0.0425	0.070
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.0425	0.032
COIL	COIL, CLN80: Coilin	0.0425	0.052
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.0425	0.155
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.0425	0.026
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.0425	0.032
H1FX	H1FX: Histone H1x	0.0425	0.0425
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.0425	0.191
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.0425	0.0425
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.0425	0.307
ERG	ERG: Transcriptional regulator ERG	0.0425	0.032
ZNF267	ZNF267: Zinc finger protein 267	0.0425	0.307
STK16	N/A	0.0425	0.0425
WDR1	N/A	0.0425	0.155
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.0425	0.307
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.0425	0.0425
NFATC1	N/A	0.0425	0.077
FRG1	FRG1: Protein FRG1	0.040	0.040
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.066
CASP3	CASP3, CPP32: Caspase-3 precursor	0.040	0.032
TRIP13	TRIP13: Thyroid receptor-interacting protein 13	0.040	0.090
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.040	0.066
RPL8	RPL8: 60S ribosomal protein L8	0.040	0.040
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.040	0.032
QARS	QARS: Glutaminyl-tRNA synthetase	0.040	0.040
HNRPK	N/A	0.040	0.040
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.040	3.51
ME2	ME2: NAD-dependent malic enzyme, mitochondrial precursor	0.040	0.040
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.040	0.040
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.040	0.040
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.040	0.066
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.040	0.040
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	0.040	0.032
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.040	0.040
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.040	0.066
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.040	0.040
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.040	0.040
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.040	0.066
HSP90AA1	Hsp89-alpha-delta-N	0.040	0.066
MTHFD1	MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic	0.040	0.032
THOC1	THOC1, HPR1: THO complex subunit 1	0.040	0.040
EEF1B2	EEF1B2, EEF1B, EF1B: Elongation factor 1-beta	0.040	0.040
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.040	0.066
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.040	0.066
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.040	0.032
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.040	0.040
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.040	0.032
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.040	0.040
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.038	0.038
BRPF1	BRPF1, BR140: Peregrin	0.038	0.171
MLL	MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX	0.038	0.136
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.038	0.038
SOX4	SOX4: Transcription factor SOX-4	0.038	0.038
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.038	0.114
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.038	0.046
MYH9	MYH9: Myosin-9	0.038	0.029
ZNF551	N/A	0.038	0.136
GCN5L2	GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2	0.038	0.071
ZNF335	ZNF335: Zinc finger protein 335	0.038	0.136
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.038	0.029
GGCX	GGCX, GC: Vitamin K-dependent gamma-carboxylase	0.038	0.038
MAFG	MAFG: Transcription factor MafG	0.038	0.046
PCAF	PCAF: Histone acetyltransferase PCAF	0.038	0.054
RELA	RELA, NFKB3: Transcription factor p65	0.038	0.086
RANBP9	RANBP9, RANBPM: Ran-binding protein 9	0.038	0.046
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.038	0.275
HDAC6	HDAC6, JM21: Histone deacetylase 6	0.038	0.069
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.038	0.038
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.038	0.038
CRSP2	MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol	0.038	0.038
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.038	0.225
COPA	COPA: Coatomer subunit alpha	0.038	0.139
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.038	0.046
COPE	COPE: Coatomer subunit epsilon	0.038	0.046
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.038	0.225
CDK6	CDK6: Cell division protein kinase 6	0.038	0.038
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.038	0.038
DUSP22	DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22	0.038	0.046
FZR1	N/A	0.038	0.046
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.038	0.038
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.038	0.038
TSC1	TSC1, KIAA0243, TSC: Hamartin	0.038	0.029
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.038	0.038
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.038	0.029
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.038	0.139
SEC31L1	N/A	0.038	0.233
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.038	0.046
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.046
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.038	0.139
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.038	0.046
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.038	0.171
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.036	0.027
YWHAQ	YWHAQ: 14-3-3 protein theta	0.036	0.206
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.036	0.036
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.027
IPO7	IPO7: Uncharacterized protein IPO7	0.036	0.0446
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.032	0.191
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.032	0.032
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.032	0.077
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.026
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.032	0.032
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.032	0.032
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.032	0.026
PRKAA1	N/A	0.032	0.032
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.032	0.032
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.032	0.096
ZFX	ZFX: Zinc finger X-chromosomal protein	0.032	0.191
GTF3C1	N/A	0.032	0.032
RGS14	N/A	0.032	0.026
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.032	0.032
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.032	0.032
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.032	0.026
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.032	0.0425
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.032	0.0425
MECP2	MECP2: Methyl-CpG-binding protein 2	0.032	0.152
STAT2	STAT2: Signal transducer and activator of transcription 2	0.032	0.077
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.032	0.052
XRCC4	N/A	0.032	0.0425
CARS	CARS: Cysteinyl-tRNA synthetase, cytoplasmic	0.032	0.040
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.032	0.040
RPS10	RPS10: 40S ribosomal protein S10	0.032	0.032
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.032	0.032
PPARBP	N/A	0.032	0.032
TBCE	TBCE: Tubulin-specific chaperone E	0.032	0.040
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.032	0.066
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.032	0.032
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.032	0.185
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.032	0.040
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.032	0.185
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.032	0.040
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.032	0.040
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.032	0.148
PPID	PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase	0.032	8.55
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.032	0.0818
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.032	0.112
EEF2	EEF2, EF2: Elongation factor 2	0.032	0.032
EIF4G3	EIF4G3: Eukaryotic translation initiation factor 4 gamma 3	0.029	0.038
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.029	0.114
DYNC1LI1	DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1	0.029	0.046
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.029	0.114
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.029	0.069
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.029	0.086
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.029	0.063
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.029	0.046
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.029
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.029	0.038
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.029	0.069
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.029	0.038
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.029	0.114
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.029	0.071
GATA2	N/A	0.029	0.029
STK10	STK10: Uncharacterized protein STK10	0.029	0.029
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.029	0.114
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.029	0.029
CLASP1	CLASP1, KIAA0622, MAST1: CLIP-associating protein 1	0.029	0.029
POLB	POLB: DNA polymerase beta	0.029	0.038
MTF1	MTF1: Metal regulatory transcription factor 1	0.029	0.275
CORO1C	CORO1C, CRNN4: Coronin-1C	0.029	0.188
GSK3B	N/A	0.029	0.046
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.029	0.038
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.029	0.114
CCNH	CCNH: Cyclin-H	0.029	0.139
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.029	0.171
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.029	0.069
WDR44	WDR44: WD repeat-containing protein 44	0.029	0.038
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	0.029	0.086
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.029	0.225
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.029	0.029
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.029	1.22
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.029	0.139
CREBBP	CREBBP, CBP: CREB-binding protein	0.029	0.054
EML4	EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4	0.029	0.069
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.029	0.038
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.083
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
CABLES1	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
C20orf18	N/A	0.028	0.083
UHRF1		0.028	0.083
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.165
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.165
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
C13orf8	N/A	0.028	0.028
PPEF1	N/A	0.028	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.165
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.165
MAPKAPK5	N/A	0.028	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
ZNF265	N/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
HDAC8	N/A	0.028	0.083
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.165
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
SNRPB	N/A	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.165
DSP	DSP: Desmoplakin	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.028	0.083
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
WDR54	N/A	0.028	0.083
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.028	0.083
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.028	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.028
CORO6	N/A	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
IRF7	N/A	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.083
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.028	0.028
DUSP15	N/A	0.028	0.028
RAB4A	N/A	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
BID	BID: BH3-interacting domain death agonist	0.028	0.028
MAPK15	N/A	0.028	0.028
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.028	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.165
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.028
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.028	0.028
PHLDB2	N/A	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.028	0.083
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.028
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.165
HES6	HES6: Transcription cofactor HES-6	0.028	0.028
KIF1B	N/A	0.028	0.028
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.028	0.083
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.028	0.050
HD	HD, IT15: Huntingtin	0.027	0.075
ERF	ERF: ETS domain-containing transcription factor ERF	0.026	0.032
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.026	0.032
GRLF1	N/A	0.026	0.026
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.026
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.026
PER2	PER2, KIAA0347: Period circadian protein homolog 2	0.026	0.026
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.026	0.152
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.026	0.032
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.026	0.032
MAPK4	MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4	0.026	0.026
MARK2	N/A	0.026	0.026
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.025	0.025
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.075
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.025	0.075
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.025	0.075
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.075
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
BCOR	N/A	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.025
LMNA	LMNA, LMN1: Lamin-A/C	0.025	0.025
MAX	MAX: Protein max	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.075
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.075
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.025
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.025	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.148
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
TCEA1	N/A	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.148
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.148
CCNT2	CCNT2: Cyclin-T2	0.025	0.075
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.025	0.025
NUP98	N/A	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.075
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
KCTD1		0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.148
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.025
CAMKK1	N/A	0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.148
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
FLJ23436	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.075
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.148
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.025	0.148
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.025
CAMK2A	N/A	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.025
NIPBL	N/A	0.025	0.025
CDC2	CDC2: Cell division control protein 2 homolog	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.148
GRK6	N/A	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	0.025
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.075
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
C20orf77	N/A	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.075
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.025	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.075
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.025
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
HDAC7A	N/A	0.025	0.075
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.025
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.148
DIDO1	N/A	0.025	0.075
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.025
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.075
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.025
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
GIT2	N/A	0.025	0.075
EEF2K	EEF2K: Elongation factor 2 kinase	0.025	0.025
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.025	0.075
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.075
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.025
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
SOX8	SOX8: Transcription factor SOX-8	0.025	0.025
ATXN2L	N/A	0.025	0.025
HTATIP	N/A	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.148
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.025
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.025	0.025
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
SEC13L1	N/A	0.025	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.148
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.075
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.025
BRD4	N/A	0.025	0.047
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.148
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.025	0.075
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.148
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
RNF20		0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
NES	N/A	0.025	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.025	0.075
SON		0.025	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.025
PRKCB1	N/A	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.025
NOLC1	NOLC1, KIAA0035: Nucleolar phosphoprotein p130	0.025	0.025
PTGES3	PTGES3, P23, TEBP: Prostaglandin E synthase 3	0.025	0.053

0.347

Total Score

10.80