PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between LIG1 and CDC6

The interaction score between LIG1 and CDC6 is 17.90.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between LIG1 and CDC6 = 0.77

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.013

Orthology

Organism	LIG1 Orthologue		CDC6 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
bakers yeast	YDL164C	1	YJL194W	1
worm	Q27474	1	P91155	1
fly	Q960P4	1	Q9VSM9	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

No domains were used in calculating likelihood of interaction

0.028

Post-translational Modifications

Protein: LIG1

PTM	Residue	Reference
Phosphorylation	66	PubMed, HPRD
Phosphorylation	76	PubMed, HPRD
Phosphorylation	141	PubMed, HPRD
Phosphorylation	195	PubMed, HPRD
Phosphorylation	911	PubMed, HPRD
Phosphoserine	66	HPRD
Phosphoserine	76	HPRD
Phosphoserine	141	HPRD
Phosphoserine	911	HPRD
Phosphothreonine	195	HPRD

Protein: CDC6

PTM	Residue	Reference
Phosphorylation	54	PubMed, HPRD
Phosphorylation	74	PubMed, HPRD
Phosphorylation	106	PubMed, HPRD

Localisation

Protein: LIG1

Localisation	Reference
Nucleus	HPRD
Nucleoplasm	HPRD

Protein: CDC6

Localisation	Reference
Nucleus	HPRD
Cytoplasm	HPRD

Transitive Score

The common interactors between LIG1 and CDC6 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between LIG1 andCDC6. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , LIG1 has 892 interactors and CDC6 has 931 interactors of which there are 691 common interactors.

Common Interactor	Name of Common Interactor	Score for LIG1-Interactor (?)	Score for CDC6-Interactor (?)
PCNA	PCNA: Proliferating cell nuclear antigen	73.00	1.62
FEN1	FEN1, RAD2: Flap endonuclease 1	12.60	0.0479
UBE2R2	UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2	3.39	3.39
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	1.26	1.03
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.704	0.471
ESPL1	N/A	0.307	0.307
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.307	0.515
DNMT1	DNMT1, AIM, DNMT: DNA	0.307	0.087
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.307	0.087
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.307	0.307
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.307	0.087
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.307	0.430
UBE2G1	UBE2G1, UBE2G: Ubiquitin-conjugating enzyme E2 G1	0.297	0.184
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.276	0.129
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.276	0.385
KIF11	N/A	0.276	0.276
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.276	0.385
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.276	0.129
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.276	431.00
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.276	0.276
MCM3	MCM3: DNA replication licensing factor MCM3	0.276	1.62
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.276	0.078
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.276	0.078
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.129
CBX3	CBX3: Chromobox protein homolog 3	0.276	0.078
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.276	0.233
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.251	0.032
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.191	0.026
TCOF1	N/A	0.144	0.070
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.144	0.917
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.070
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.144	0.087
MKI67	MKI67: Antigen KI-67	0.144	0.917
SET	SET: Protein SET	0.144	0.070
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.144	0.132
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.144	0.515
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.144	0.515
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.144	0.144
UBAP2	N/A	0.144	0.070
RBM14	RBM14, SIP: RNA-binding protein 14	0.144	0.052
CENPA	CENPA: Histone H3-like centromeric protein A	0.144	0.307
PTMA	N/A	0.144	0.070
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.144	0.070
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.141	0.066
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.141	0.066
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.139	0.029
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.129	0.385
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.129	0.063
SSB	SSB: Lupus La protein	0.129	0.078
MYBL2	MYBL2, BMYB: Myb-related protein B	0.129	0.385
CDK4	CDK4: Cell division protein kinase 4	0.129	0.129
TIAL1	TIAL1: Nucleolysin TIAR	0.129	0.063
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.129	0.385
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.129	0.233
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	0.276
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.129	0.078
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.129	0.078
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.129	0.129
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.129	0.063
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.129	0.063
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.129	0.129
CDK2	CDK2: Cell division protein kinase 2	0.129	6.86
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.078
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.129	0.063
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.129	0.146
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.129	0.046
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.129	0.129
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.129	0.078
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.129	0.063
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.129	0.129
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.129
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.078
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.129	0.063
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.129	0.372
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.129	0.129
WEE1	WEE1: Wee1-like protein kinase	0.129	0.078
NOL1	N/A	0.129	0.078
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.129	0.233
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.078
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.233
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.129	1.62
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.129	0.078
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.129	0.063
CCNB1	Cyclin B1	0.129	86.60
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.129	0.129
H2AFX	H2AFX, H2AX: Histone H2A.x	0.129	0.129
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.129	0.078
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.129	0.046
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.129	0.063
CDC20	CDC20: Cell division cycle protein 20 homolog	0.129	0.276
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.129	0.763
POLA2	POLA2: DNA polymerase subunit alpha B	0.129	0.129
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.129	0.063
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.129	0.461
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.063
UNG	N/A	0.129	0.078
NUP153	N/A	0.129	0.078
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.078
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.118
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.078
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.129	0.461
ROCK1	ROCK1: Rho-associated protein kinase 1	0.127	0.032
PLEK	PLEK, P47: Pleckstrin	0.127	0.026
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.114	0.029
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.097	0.028
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.091	0.027
CRKL	CRKL: Crk-like protein	0.090	0.032
MATR3	MATR3, KIAA0723: Matrin-3	0.087	0.155
NBN	NBN, NBS, NBS1, P95: Nibrin	0.087	0.155
ABCF1	N/A	0.087	0.070
KIF23	N/A	0.087	0.144
RB1	RB1: Retinoblastoma-associated protein	0.087	0.416
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.087	0.052
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.087	0.416
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.087	0.070
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.087	0.127
DDX21	DDX21: Nucleolar RNA helicase 2	0.087	0.070
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.087	0.070
TRRAP	N/A	0.087	0.052
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.087	0.0425
GNB2L1	Lung cancer oncogene 7	0.087	0.0425
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.052
TOP2B	N/A	0.087	0.052
FNBP1	N/A	0.087	0.029
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.086	0.035
DOK1	DOK1: Docking protein 1	0.086	0.029
NF2	NF2, SCH: Merlin	0.083	0.028
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.078	0.225
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.078	0.063
MTA1	MTA1: Metastasis-associated protein MTA1	0.078	0.188
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.078	0.114
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.078	0.114
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.078	0.046
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.078	0.063
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.078	0.063
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.078	0.087
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.078	0.114
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.038
WBSCR20A	N/A	0.078	0.038
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.078	0.118
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.046
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.078	0.063
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.046
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.063
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.078	0.038
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.078	0.118
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.078	0.063
TP53	TP53, P53: Cellular tumor antigen p53	0.078	0.146
PHF10	N/A	0.078	0.046
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.063
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.078	0.129
PPP1R8	N/A	0.078	0.139
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.046
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.078	0.063
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.078	0.461
HDAC2	HDAC2: Histone deacetylase 2	0.078	0.118
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.046
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.078	0.078
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.038
YY1	YY1: Transcriptional repressor protein YY1	0.078	0.114
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.078	0.038
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	0.276
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.078	0.078
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.078	0.038
MDN1	MDN1, KIAA0301: Midasin	0.078	0.275
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.078	0.129
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.046
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.046
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.078	0.114
PLEKHA5	PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member	0.077	0.026
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.075	0.025
ELMO1	N/A	0.075	0.047
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.075	0.025
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.074	0.157
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.0446
FUBP1	N/A	0.074	0.027
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.070	0.052
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.070	0.052
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.0425
KIAA0853	N/A	0.070	0.052
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.070	0.032
CHUK	N/A	0.070	0.052
SREBF2	N/A	0.070	0.052
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.070	0.155
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.070	0.0425
ELF1	ELF1: ETS-related transcription factor Elf-1	0.070	0.077
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.070	0.0425
RBM6	RBM6, DEF3: RNA-binding protein 6	0.070	0.032
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.052
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.052
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.070	0.0425
ARFGAP1	N/A	0.070	0.0425
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.070	0.515
API5	N/A	0.070	0.052
IRF3	IRF3: Interferon regulatory factor 3	0.070	0.077
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.070	0.127
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.0425
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.070	0.032
MYB	MYB: Myb proto-oncogene protein	0.070	0.210
TGIF2	TGIF2: Homeobox protein TGIF2	0.070	0.155
ELMO2	ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2	0.069	0.028
RAPGEF6	RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6	0.067	0.041
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.067	0.033
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.067	0.041
XPO1	XPO1, CRM1: Exportin-1	0.066	0.137
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.066	0.503
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.066	0.032
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.066
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.066	0.040
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.040
HSPD1		0.066	0.066
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.066	0.066
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.066	0.040
TK1	TK1: Thymidine kinase, cytosolic	0.066	0.066
LDHB	LDHB: L-lactate dehydrogenase B chain	0.066	0.032
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.066
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.066	0.066
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.066	0.066
CTPS	CTPS: CTP synthase 1	0.066	0.066
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.066	0.040
CDC23	CDC23: Cell division cycle protein 23 homolog	0.066	0.040
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.066
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.063	0.038
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.038
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.063	0.063
CUL5	CUL5, VACM1: Cullin-5	0.063	0.029
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.063	0.275
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.063	0.086
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.118
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.225
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.063	0.046
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.063	0.038
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.046
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.063	0.038
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.063	0.063
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.063	0.029
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.029
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.063	0.038
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.063	0.046
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.063	0.063
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.063	0.038
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.063
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.046
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.114
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.063	0.114
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.063	0.225
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.063	0.029
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.063	0.038
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.038
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.063	0.046
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.063	0.046
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.063	0.233
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.063	0.087
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.063	0.038
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.063	0.139
SAPS3	N/A	0.063	0.038
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.069
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.038
GAB1	GAB1: GRB2-associated-binding protein 1	0.062	0.026
TPX2	TPX2, C20orf1, C20orf2, DIL2, HCA519: Targeting protein for Xklp2	0.053	0.053
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.052	0.032
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.052	0.127
HIVEP1	N/A	0.052	0.096
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.052	0.052
AFF1	N/A	0.052	0.032
NCOA3	N/A	0.052	0.026
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.052	0.0425
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.052	0.052
IFI16	N/A	0.052	0.032
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.052	0.155
SMARCC2	N/A	0.052	0.032
SP100	N/A	0.052	0.077
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.052	0.032
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.052	0.191
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.052	0.096
XRCC1	XRCC1: DNA-repair protein XRCC1	0.052	0.127
EMD	EMD, EDMD, STA: Emerin	0.052	0.032
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.032
EZH2	EZH2: Enhancer of zeste homolog 2	0.0479	0.0479
KNTC2	KNTC2, HEC, HEC1: Kinetochore protein Hec1	0.0479	0.0479
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.047	0.025
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.038
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.046	0.038
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.046	0.029
SYMPK	SYMPK, SPK: Symplekin	0.046	0.114
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.046	0.038
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.046	0.038
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.046	0.029
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.046	0.038
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.046	0.029
SRF	SRF: Serum response factor	0.046	0.114
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.046	0.086
EP300	N/A	0.046	0.029
COPB2	COPB2: Coatomer subunit beta'	0.046	0.046
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.046	0.029
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.046	0.114
CDK7	CDK7, MO15: Cell division protein kinase 7	0.046	0.046
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.046	0.029
WDR79	N/A	0.046	0.063
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.046	0.029
SP3	SP3: Transcription factor Sp3	0.046	0.086
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.046	0.046
CSDA	CSDA, DBPA: DNA-binding protein A	0.046	0.114
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.046	0.139
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.046	0.029
DIAPH1	Diaphanous 1	0.046	0.029
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.046	0.063
RPS6KB1	N/A	0.046	0.038
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.046	0.054
RUNX1	N/A	0.046	0.046
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.046	0.086
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.029
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.046	0.086
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.046	0.136
TOP3A	TOP3A, TOP3: DNA topoisomerase 3-alpha	0.046	0.038
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.054
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.046	0.029
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.046	0.038
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.046	0.029
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.046	0.038
KLHDC4	N/A	0.046	0.029
RBM7		0.046	0.038
ARMET	ARMET, ARP: Protein ARMET precursor	0.046	0.029
CUL4B	N/A	0.046	0.029
FKBP4	FKBP4: FK506-binding protein 4	0.046	0.046
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.046	0.029
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.046	0.029
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.046	0.086
TAL1	TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1	0.046	0.139
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.046	0.069
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.0446
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.0446	0.036
PHB2	PHB2, BAP, REA: Prohibitin-2	0.0446	0.036
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.0446	0.0446
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.0425	0.0425
GTF2F2	N/A	0.0425	0.155
COIL	COIL, CLN80: Coilin	0.0425	0.032
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.0425	0.060
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.0425	0.026
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.0425	0.0425
H1FX	H1FX: Histone H1x	0.0425	0.077
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.0425	0.077
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.0425	0.039
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.0425	0.077
ERG	ERG: Transcriptional regulator ERG	0.0425	0.127
ZNF267	ZNF267: Zinc finger protein 267	0.0425	0.096
STK16	N/A	0.0425	0.0425
WDR1	N/A	0.0425	0.026
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.0425	0.077
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.0425	0.0425
NFATC1	N/A	0.0425	0.152
STAM	STAM, STAM1: Signal transducing adapter molecule 1	0.041	0.041
ABI1	ABI1, SSH3BP1: Abl interactor 1	0.04	0.049
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.032
TRIP13	TRIP13: Thyroid receptor-interacting protein 13	0.040	0.503
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.040	0.032
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.040	0.032
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.040	0.040
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.040	0.032
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.040	0.245
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.040	0.040
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.040	0.040
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.040	0.032
HSP90AA1	Hsp89-alpha-delta-N	0.040	0.032
MTHFD1	MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic	0.040	0.040
THOC1	THOC1, HPR1: THO complex subunit 1	0.040	0.032
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.040	0.040
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.040	0.032
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.040	0.067
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.040	0.032
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.038	0.029
BRPF1	BRPF1, BR140: Peregrin	0.038	0.136
MLL	MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX	0.038	0.136
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.038	0.069
SOX4	SOX4: Transcription factor SOX-4	0.038	0.114
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.038	0.069
ZNF551	N/A	0.038	0.114
GCN5L2	GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2	0.038	0.171
ZNF335	ZNF335: Zinc finger protein 335	0.038	0.069
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.038	0.029
GGCX	GGCX, GC: Vitamin K-dependent gamma-carboxylase	0.038	0.046
MAFG	MAFG: Transcription factor MafG	0.038	0.225
PCAF	PCAF: Histone acetyltransferase PCAF	0.038	0.171
RELA	RELA, NFKB3: Transcription factor p65	0.038	0.069
RANBP9	RANBP9, RANBPM: Ran-binding protein 9	0.038	0.029
HDAC6	HDAC6, JM21: Histone deacetylase 6	0.038	0.071
CRSP2	MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol	0.038	0.046
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.038	0.069
METTL1	METTL1, C12orf1: tRNA	0.038	0.038
COPA	COPA: Coatomer subunit alpha	0.038	0.029
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.038	0.069
CDK6	CDK6: Cell division protein kinase 6	0.038	0.038
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.038	0.136
FZR1	N/A	0.038	0.038
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.038	0.029
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.038	0.029
TSC1	TSC1, KIAA0243, TSC: Hamartin	0.038	0.029
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.038	0.086
SATB1	SATB1: DNA-binding protein SATB1	0.038	0.056
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.038	0.043
SEC31L1	N/A	0.038	0.029
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.038	0.029
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.038
ATM	ATM: Serine-protein kinase ATM	0.038	0.056
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.038	0.069
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.036	0.091
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.036	0.036
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.074
IPO7	IPO7: Uncharacterized protein IPO7	0.036	0.124
STAM2	STAM2: Signal transducing adapter molecule 2	0.033	0.033
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.032	0.096
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.032	0.096
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.026
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.032	0.032
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.032	0.077
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.032	0.039
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.032	0.062
ZFX	ZFX: Zinc finger X-chromosomal protein	0.032	0.096
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.032	0.077
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.032	0.0425
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.032	0.077
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.032	0.032
STAT2	STAT2: Signal transducer and activator of transcription 2	0.032	0.077
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.032	0.026
XRCC4	N/A	0.032	0.032
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.032	0.032
TRAP1	TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor	0.032	0.032
THOP1	THOP1: Thimet oligopeptidase	0.032	0.032
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.032	0.245
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.032	65.00
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.032	0.111
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.032	0.051
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.032	0.0818
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.032	0.181
EIF4G3	EIF4G3: Eukaryotic translation initiation factor 4 gamma 3	0.029	0.056
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.029	0.056
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.029	0.038
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.029	0.029
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.038
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.029	0.069
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.029	0.097
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.029	0.136
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.029	0.136
GATA2	N/A	0.029	0.029
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.029	0.086
CLASP1	CLASP1, KIAA0622, MAST1: CLIP-associating protein 1	0.029	0.056
MTF1	MTF1: Metal regulatory transcription factor 1	0.029	0.086
CORO1C	CORO1C, CRNN4: Coronin-1C	0.029	0.029
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.029	0.043
LEF1	LEF1: Lymphoid enhancer-binding factor 1	0.029	0.086
CCNH	CCNH: Cyclin-H	0.029	0.136
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.029	0.086
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.029	0.086
ETS1	ETS1, EWSR2: Protein C-ets-1	0.029	0.056
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	0.029	0.086
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.029	0.069
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.029	0.114
CREBBP	CREBBP, CBP: CREB-binding protein	0.029	0.097
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.029	0.043
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
CABLES1	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
C20orf18	N/A	0.028	0.052
UHRF1		0.028	0.028
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.083
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.028	0.083
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
C13orf8	N/A	0.028	0.028
PPEF1	N/A	0.028	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.083
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.083
MAPKAPK5	N/A	0.028	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
ZNF265	N/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
HDAC8	N/A	0.028	0.052
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.083
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
SNRPB	N/A	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.083
DSP	DSP: Desmoplakin	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.028	0.165
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
WDR54	N/A	0.028	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.028	0.165
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.028	0.052
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.083
CORO6	N/A	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
IRF7	N/A	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.028	0.083
DUSP15	N/A	0.028	0.028
RAB4A	N/A	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
BID	BID: BH3-interacting domain death agonist	0.028	0.028
MAPK15	N/A	0.028	0.052
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.028	0.083
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.083
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.028	0.083
PHLDB2	N/A	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.028	0.052
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.028
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.083
HES6	HES6: Transcription cofactor HES-6	0.028	0.052
KIF1B	N/A	0.028	0.028
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.028	0.028
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.028	0.028
C18orf56	N/A	0.027	0.027
MCM10	N/A	0.027	0.027
RAD51AP1	N/A	0.027	0.027
SMC4L1	N/A	0.027	0.027
KIAA0101	PAF, KIAA0101, L5, NS5ATP9: PCNA-associated factor	0.027	0.027
ZWINT	N/A	0.027	0.027
HD	HD, IT15: Huntingtin	0.027	0.075
ERF	ERF: ETS domain-containing transcription factor ERF	0.026	0.096
GRLF1	N/A	0.026	0.026
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.096
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.026
PER2	PER2, KIAA0347: Period circadian protein homolog 2	0.026	0.026
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.026	0.077
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.026	0.152
MDM4	MDM4, MDMX: Mdm4 protein	0.026	0.039
GTF3C4	GTF3C4: General transcription factor 3C polypeptide 4	0.026	0.026
MAPK4	MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4	0.026	0.026
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.025	0.075
MAP2K3	N/A	0.025	0.025
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.025	0.075
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.075
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.025	0.148
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.025	0.148
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
BCOR	N/A	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.025
LMNA	LMNA, LMN1: Lamin-A/C	0.025	0.025
MAX	MAX: Protein max	0.025	0.047
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.075
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.075
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.025	0.075
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.075
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
TCEA1	N/A	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.047
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
CCNT2	CCNT2: Cyclin-T2	0.025	0.148
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.025	0.047
NUP98	N/A	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
KCTD1		0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.075
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.075
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.025
CAMKK1	N/A	0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.075
FLJ23436	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.148
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.047
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.025	0.075
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.025
CAMK2A	N/A	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.148
NIPBL	N/A	0.025	0.075
CDC2	CDC2: Cell division control protein 2 homolog	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025
GRK6	N/A	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	0.025
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
C20orf77	N/A	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.047
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.025	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.025
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
HDAC7A	N/A	0.025	0.047
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.075
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.075
DIDO1	N/A	0.025	0.025
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.075
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.025
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
GIT2	N/A	0.025	0.047
EEF2K	EEF2K: Elongation factor 2 kinase	0.025	0.025
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.025	0.075
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.047
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.025
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
SOX8	SOX8: Transcription factor SOX-8	0.025	0.075
ATXN2L	N/A	0.025	0.025
HTATIP	N/A	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.148
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.075
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.025
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.025	0.025
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
SEC13L1	N/A	0.025	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.075
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.075
BRD4	N/A	0.025	0.148
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.025	0.047
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.075
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.148
RNF20		0.025	0.075
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
NES	N/A	0.025	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.025	0.148
SON		0.025	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.025
PRKCB1	N/A	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.075
PTTG1	PTTG1, EAP1, PTTG, TUTR1: Securin	0.025	0.025
TACC3	TACC3, ERIC1: Transforming acidic coiled-coil-containing protein 3	0.025	0.068
GMNN	GMNN: Geminin	0.025	0.053
GTSE1	GTSE1: G2 and S phase-expressed protein 1	0.025	0.025
DBF4	DBF4, ASK: Protein DBF4 homolog	0.025	0.025

0.347

Total Score

17.90