PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between LIG1 and CCNB1

The interaction score between LIG1 and CCNB1 is 17.90.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between LIG1 and CCNB1 = 0.74

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.013

Orthology

Organism	LIG1 Orthologue		CCNB1 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
bakers yeast	YDL164C	1	YPR119W	0.321
worm	Q27474	1	Q10653	1
worm	Q27474	1	O45926	0.463
worm	Q27474	1	Q9BLB5	0.463
fly	Q960P4	1	P20439	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

No domains were used in calculating likelihood of interaction

0.028

Post-translational Modifications

Protein: LIG1

PTM	Residue	Reference
Phosphorylation	66	PubMed, HPRD
Phosphorylation	76	PubMed, HPRD
Phosphorylation	141	PubMed, HPRD
Phosphorylation	195	PubMed, HPRD
Phosphorylation	911	PubMed, HPRD
Phosphoserine	66	HPRD
Phosphoserine	76	HPRD
Phosphoserine	141	HPRD
Phosphoserine	911	HPRD
Phosphothreonine	195	HPRD

Protein: CCNB1

PTM	Residue	Reference
Phosphorylation	126	PubMed, HPRD
Phosphorylation	128	PubMed, HPRD
Phosphorylation	133	PubMed, HPRD
Phosphorylation	147	PubMed, HPRD

Localisation

Protein: LIG1

Localisation	Reference
Nucleus	HPRD
Nucleoplasm	HPRD

Protein: CCNB1

Localisation	Reference
Nucleus	HPRD
Plasma membrane	HPRD
Nucleolus	HPRD
Centrosome	HPRD
Cytoplasm	HPRD
Cytoskeleton	HPRD

Transitive Score

The common interactors between LIG1 and CCNB1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between LIG1 andCCNB1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , LIG1 has 892 interactors and CCNB1 has 1142 interactors of which there are 718 common interactors.

Common Interactor	Name of Common Interactor	Score for LIG1-Interactor (?)	Score for CCNB1-Interactor (?)
PCNA	PCNA: Proliferating cell nuclear antigen	73.00	0.822
FEN1	FEN1, RAD2: Flap endonuclease 1	12.60	0.0479
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	1.26	0.032
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.704	0.471
ESPL1	N/A	0.307	0.307
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.307	0.260
DNMT1	DNMT1, AIM, DNMT: DNA	0.307	0.087
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.307	0.087
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.307	0.307
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.307	0.087
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.307	0.144
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.276	6.86
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.276	0.385
KIF11	N/A	0.276	0.276
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.276	0.822
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.276	0.129
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.276	1.62
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.276	0.129
MCM3	MCM3: DNA replication licensing factor MCM3	0.276	40.60
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.276	0.129
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.276	0.078
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.276
CBX3	CBX3: Chromobox protein homolog 3	0.276	0.233
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.276	0.188
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.251	0.0425
TCOF1	N/A	0.144	0.070
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.144	0.852
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.087
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.144	0.144
MKI67	MKI67: Antigen KI-67	0.144	0.307
SET	SET: Protein SET	0.144	0.087
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.144	0.210
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.144	0.260
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.144	0.070
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.144	0.087
UBAP2	N/A	0.144	0.087
RBM14	RBM14, SIP: RNA-binding protein 14	0.144	0.070
CENPA	CENPA: Histone H3-like centromeric protein A	0.144	0.307
PTMA	N/A	0.144	0.070
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.144	0.087
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.141	0.066
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.141	0.040
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.139	0.171
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.139	0.136
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.129	0.763
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.129	0.063
SSB	SSB: Lupus La protein	0.129	0.078
MYBL2	MYBL2, BMYB: Myb-related protein B	0.129	0.385
CDK4	CDK4: Cell division protein kinase 4	0.129	0.763
TIAL1	TIAL1: Nucleolysin TIAR	0.129	0.063
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.129	0.233
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.129	0.078
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	1.62
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.129	0.078
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.129	0.063
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.129	0.078
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.129	2.47
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.129	0.063
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.129	86.60
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.129	0.129
CDK2	CDK2: Cell division protein kinase 2	0.129	21.70
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.078
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.129	0.063
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.129	0.146
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.129	0.046
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.129	0.385
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.129	0.129
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.129	0.078
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.129	0.233
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.129
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.078
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.129	0.063
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.129	0.139
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.129	0.129
WEE1	WEE1: Wee1-like protein kinase	0.129	0.385
NOL1	N/A	0.129	0.063
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.129	0.188
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.129
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.063
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.129	1.62
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.129	0.078
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.129	0.063
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.129	0.276
H2AFX	H2AFX, H2AX: Histone H2A.x	0.129	0.276
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.129	0.063
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.129	0.046
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.129	0.078
CDC20	CDC20: Cell division cycle protein 20 homolog	0.129	0.827
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.129	0.763
POLA2	POLA2: DNA polymerase subunit alpha B	0.129	0.078
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.129	0.078
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.129	0.385
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.078
UNG	N/A	0.129	0.078
NUP153	N/A	0.129	0.078
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.078
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.188
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.078
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.129	0.385
ROCK1	ROCK1: Rho-associated protein kinase 1	0.127	0.191
PLEK	PLEK, P47: Pleckstrin	0.127	0.026
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.114	0.171
SOS1	SOS1: Son of sevenless homolog 1	0.114	0.056
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.111	0.067
CSK	CSK: Tyrosine-protein kinase CSK	0.090	0.051
CRKL	CRKL: Crk-like protein	0.090	0.032
MATR3	MATR3, KIAA0723: Matrin-3	0.087	0.155
NBN	NBN, NBS, NBS1, P95: Nibrin	0.087	0.155
ABCF1	N/A	0.087	0.070
KIF23	N/A	0.087	0.144
RB1	RB1: Retinoblastoma-associated protein	0.087	0.416
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.087	0.052
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.087	0.260
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.087	0.070
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.087	0.155
DDX21	DDX21: Nucleolar RNA helicase 2	0.087	0.070
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.087	0.070
TRRAP	N/A	0.087	0.0425
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.087	0.032
GNB2L1	Lung cancer oncogene 7	0.087	0.052
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.070
TOP2B	N/A	0.087	0.0425
FNBP1	N/A	0.087	0.029
DOK1	DOK1: Docking protein 1	0.086	0.029
NF2	NF2, SCH: Merlin	0.083	0.028
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.078	0.086
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.078	0.078
MTA1	MTA1: Metastasis-associated protein MTA1	0.078	0.139
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.078	0.038
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.078	0.225
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.078	0.046
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.078	0.372
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.078	0.078
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.078	0.139
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.078	0.171
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.038
WBSCR20A	N/A	0.078	0.029
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.078	0.087
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.046
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.078	0.046
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.046
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.372
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.078	0.038
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.078	0.188
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.078	0.129
TP53	TP53, P53: Cellular tumor antigen p53	0.078	0.385
PHF10	N/A	0.078	0.139
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.063
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.078	0.763
PPP1R8	N/A	0.078	0.046
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.046
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.078	0.046
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.078	0.233
HDAC2	HDAC2: Histone deacetylase 2	0.078	0.233
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.046
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.078	0.233
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.046
YY1	YY1: Transcriptional repressor protein YY1	0.078	0.139
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.078	0.046
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	86.60
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.078	0.461
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.078	0.225
MDN1	MDN1, KIAA0301: Midasin	0.078	0.114
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.078	0.078
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.188
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.275
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.078	0.038
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.075	7.88
ELMO1	N/A	0.075	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.075	0.148
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.074	0.030
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.074	0.472
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.253
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.070	0.0425
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.070	0.052
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.0425
KIAA0853	N/A	0.070	0.052
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.070	0.191
CHUK	N/A	0.070	0.0425
SREBF2	N/A	0.070	0.052
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.070	0.155
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.070	0.251
ELF1	ELF1: ETS-related transcription factor Elf-1	0.070	0.191
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.070	0.032
RBM6	RBM6, DEF3: RNA-binding protein 6	0.070	0.032
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.052
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.052
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.070	0.0425
ARFGAP1	N/A	0.070	0.0425
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.070	0.210
API5	N/A	0.070	0.070
IRF3	IRF3: Interferon regulatory factor 3	0.070	0.152
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.070	0.127
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.0425
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.070	0.096
MYB	MYB: Myb proto-oncogene protein	0.070	0.127
TGIF2	TGIF2: Homeobox protein TGIF2	0.070	0.080
XPO1	XPO1, CRM1: Exportin-1	0.066	0.040
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.066	12.00
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.066	0.032
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.141
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.066	0.066
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.066	0.032
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.040
HSPD1		0.066	0.066
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.066	0.141
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.066	0.066
TK1	TK1: Thymidine kinase, cytosolic	0.066	0.141
LDHB	LDHB: L-lactate dehydrogenase B chain	0.066	0.032
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.040
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.066	0.141
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.066	0.185
CTPS	CTPS: CTP synthase 1	0.066	0.066
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.066	0.066
CDC23	CDC23: Cell division cycle protein 23 homolog	0.066	2.12
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.066
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.063	0.038
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.038
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.063	0.078
CUL5	CUL5, VACM1: Cullin-5	0.063	0.029
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.063	0.139
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.063	0.069
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.078
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.139
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.063	0.046
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.063	0.038
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.063
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.063	0.038
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.063	0.063
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.038
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.063	0.046
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.063	0.038
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.063	0.461
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.063	0.038
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.063
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.046
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.086
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.063	0.275
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.063	0.372
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.063	0.029
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.063	0.038
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.038
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.063	0.063
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.063	0.139
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.063	0.233
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.063	0.046
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.063	0.029
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.063	0.372
SAPS3	N/A	0.063	0.038
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.029
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.029
GAB1	GAB1: GRB2-associated-binding protein 1	0.062	0.026
SPTA1	SPTA1, SPTA: Spectrin alpha chain, erythrocyte	0.061	0.027
TPX2	TPX2, C20orf1, C20orf2, DIL2, HCA519: Targeting protein for Xklp2	0.053	0.053
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.052	0.026
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.052	0.096
HIVEP1	N/A	0.052	0.096
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.052	0.416
AFF1	N/A	0.052	0.0425
NCOA3	N/A	0.052	0.026
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.052	0.0425
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.052	0.070
IFI16	N/A	0.052	0.032
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.052	0.052
SMARCC2	N/A	0.052	0.032
SP100	N/A	0.052	0.096
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.052	0.191
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.052	0.096
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.052	0.077
XRCC1	XRCC1: DNA-repair protein XRCC1	0.052	0.127
EMD	EMD, EDMD, STA: Emerin	0.052	0.0425
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.026
EZH2	EZH2: Enhancer of zeste homolog 2	0.0479	0.101
KNTC2	KNTC2, HEC, HEC1: Kinetochore protein Hec1	0.0479	0.0479
PA2G4	PA2G4, EBP1: Proliferation-associated protein 2G4	0.0479	0.0479
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.047	0.148
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.029
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.046	0.114
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.046	0.029
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.046	0.038
SYMPK	SYMPK, SPK: Symplekin	0.046	0.038
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.046	0.029
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.046	0.038
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.046	0.171
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.046	0.995
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.046	0.046
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.046	0.029
SRF	SRF: Serum response factor	0.046	0.046
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.046	0.171
EP300	N/A	0.046	0.029
COPB2	COPB2: Coatomer subunit beta'	0.046	0.063
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.046	1.08
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.046	0.136
CDK7	CDK7, MO15: Cell division protein kinase 7	0.046	0.372
WDR79	N/A	0.046	0.046
SP3	SP3: Transcription factor Sp3	0.046	0.114
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.046	0.063
CSDA	CSDA, DBPA: DNA-binding protein A	0.046	0.046
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.046	0.188
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.046	0.275
DIAPH1	Diaphanous 1	0.046	1.53
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.046	0.063
RPS6KB1	N/A	0.046	0.225
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.046	0.029
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.046	0.225
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.029
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.046	0.069
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.046	0.029
TOP3A	TOP3A, TOP3: DNA topoisomerase 3-alpha	0.046	0.038
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.086
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.046	0.038
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.046	0.225
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.046	0.038
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.046	0.086
KLHDC4	N/A	0.046	0.029
RBM7		0.046	0.046
ARMET	ARMET, ARP: Protein ARMET precursor	0.046	0.038
CUL4B	N/A	0.046	0.029
FKBP4	FKBP4: FK506-binding protein 4	0.046	0.046
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.046	0.029
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.046	0.038
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.046	0.038
TAL1	TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1	0.046	0.188
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.046	0.056
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.046	0.057
LIMK2	LIMK2: LIM domain kinase 2	0.0453	0.0453
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.0446
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.0446	0.0446
PHB2	PHB2, BAP, REA: Prohibitin-2	0.0446	0.274
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.0446	0.0446
ROCK2	ROCK2, KIAA0619: Rho-associated protein kinase 2	0.044	0.088
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.044	0.044
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.0425	0.251
GTF2F2	N/A	0.0425	0.307
COIL	COIL, CLN80: Coilin	0.0425	0.032
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.0425	0.127
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.0425	0.026
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.0425	0.032
H1FX	H1FX: Histone H1x	0.0425	0.152
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.0425	0.096
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.0425	0.062
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.0425	0.062
ERG	ERG: Transcriptional regulator ERG	0.0425	0.152
ZNF267	ZNF267: Zinc finger protein 267	0.0425	0.096
STK16	N/A	0.0425	0.307
WDR1	N/A	0.0425	0.032
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.0425	0.096
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.0425	0.155
NFATC1	N/A	0.0425	0.062
ARHGAP12	ARHGAP12: Rho GTPase-activating protein 12	0.041	0.449
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.04	0.049
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.04	0.04
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.040
CASP3	CASP3, CPP32: Caspase-3 precursor	0.040	0.111
TRIP13	TRIP13: Thyroid receptor-interacting protein 13	0.040	0.484
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.040	0.040
HNRPK	N/A	0.040	0.032
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.040	0.032
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.040	0.032
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.040	0.040
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.040	0.040
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.040	0.111
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.040	0.040
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.040	0.040
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.040	0.181
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.040	0.032
HSP90AA1	Hsp89-alpha-delta-N	0.040	0.040
MTHFD1	MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic	0.040	0.040
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.040	0.040
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.040	0.040
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.040	0.032
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.040	0.032
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.040	0.032
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.038	0.029
BRPF1	BRPF1, BR140: Peregrin	0.038	0.069
MLL	MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX	0.038	0.069
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.038	0.136
SOX4	SOX4: Transcription factor SOX-4	0.038	0.069
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.038	0.136
MYH9	MYH9: Myosin-9	0.038	0.029
ZNF551	N/A	0.038	0.069
ZNF335	ZNF335: Zinc finger protein 335	0.038	0.069
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.038	0.029
GGCX	GGCX, GC: Vitamin K-dependent gamma-carboxylase	0.038	0.038
MAFG	MAFG: Transcription factor MafG	0.038	0.139
PCAF	PCAF: Histone acetyltransferase PCAF	0.038	0.038
RELA	RELA, NFKB3: Transcription factor p65	0.038	0.086
RANBP9	RANBP9, RANBPM: Ran-binding protein 9	0.038	0.029
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.038	0.136
HDAC6	HDAC6, JM21: Histone deacetylase 6	0.038	0.054
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.038	0.171
CRSP2	MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol	0.038	0.038
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.038	0.086
METTL1	METTL1, C12orf1: tRNA	0.038	0.038
COPA	COPA: Coatomer subunit alpha	0.038	0.038
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.038	0.171
COPE	COPE: Coatomer subunit epsilon	0.038	0.038
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.038	0.086
CDK6	CDK6: Cell division protein kinase 6	0.038	0.136
FZR1	N/A	0.038	2.47
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.038	0.038
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.038	0.029
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.038	0.225
SATB1	SATB1: DNA-binding protein SATB1	0.038	0.049
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.038	0.035
SEC31L1	N/A	0.038	0.038
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.029
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.038	0.136
ATM	ATM: Serine-protein kinase ATM	0.038	0.049
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.038	0.069
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.037	0.046
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.036	0.061
YWHAQ	YWHAQ: 14-3-3 protein theta	0.036	0.027
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.036	0.0446
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.027
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.036	0.044
LYN	LYN: Tyrosine-protein kinase Lyn	0.033	0.027
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.033	0.026
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	0.033	0.033
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.032	0.077
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.032	0.096
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.123
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.032	0.096
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.032	0.191
PRKAA1	N/A	0.032	0.152
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.032	0.055
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.032	0.026
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.032	0.077
ZFX	ZFX: Zinc finger X-chromosomal protein	0.032	0.077
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.032	0.026
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.032	0.127
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.032	0.048
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.032	0.191
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.032	0.123
STAT2	STAT2: Signal transducer and activator of transcription 2	0.032	0.026
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.032	0.032
XRCC4	N/A	0.032	0.032
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.032	0.032
TRAP1	TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor	0.032	0.032
THOP1	THOP1: Thimet oligopeptidase	0.032	0.032
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.032	1.26
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.032	0.032
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.032	1.03
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.032	0.137
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.032	7.30
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.032	0.032
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.032	0.040
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.032	0.051
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.032	0.051
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.032	0.111
MAP3K11	MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11	0.0308	0.049
MAP3K10	MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10	0.0308	0.056
PRKD1	PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1	0.029	0.058
BMX	N/A	0.029	0.032
LIMK1	LIMK1, LIMK: LIM domain kinase 1	0.029	0.029
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.029	0.069
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.029	0.029
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.029	0.029
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.029	0.171
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.029	0.056
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.029
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.029	0.136
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.029	0.097
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.029	0.043
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.029	0.111
STK10	STK10: Uncharacterized protein STK10	0.029	0.111
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.029	11.90
MTF1	MTF1: Metal regulatory transcription factor 1	0.029	0.086
CORO1C	CORO1C, CRNN4: Coronin-1C	0.029	0.038
GSK3B	N/A	0.029	0.029
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.029	0.171
LEF1	LEF1: Lymphoid enhancer-binding factor 1	0.029	0.069
CCNH	CCNH: Cyclin-H	0.029	0.171
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.029	0.086
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.029	0.086
ETS1	ETS1, EWSR2: Protein C-ets-1	0.029	0.111
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	0.029	0.086
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.029	0.056
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.029	0.111
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.029	0.225
PSKH1	PSKH1: Serine/threonine-protein kinase H1	0.029	0.171
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.029	0.136
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.083
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
CABLES1	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
C20orf18	N/A	0.028	0.052
UHRF1		0.028	0.083
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.083
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.028	0.165
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
C13orf8	N/A	0.028	0.028
PPEF1	N/A	0.028	0.083
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.083
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.083
MAPKAPK5	N/A	0.028	0.083
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.165
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
ZNF265	N/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
HDAC8	N/A	0.028	0.083
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.083
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.083
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
SNRPB	N/A	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.083
DSP	DSP: Desmoplakin	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.028	0.083
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
WDR54	N/A	0.028	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.028	0.083
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.028	0.083
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.165
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.052
CORO6	N/A	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
IRF7	N/A	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.028	0.165
DUSP15	N/A	0.028	0.028
RAB4A	N/A	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
BID	BID: BH3-interacting domain death agonist	0.028	0.028
MAPK15	N/A	0.028	0.165
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.028	0.165
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.083
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.083
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.083
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.052
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.028	0.165
PHLDB2	N/A	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.165
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.083
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.083
HES6	HES6: Transcription cofactor HES-6	0.028	0.052
KIF1B	N/A	0.028	0.028
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.028	0.028
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
TMPO	N/A	0.027	0.027
C18orf56	N/A	0.027	0.027
SMC4L1	N/A	0.027	0.027
KIAA0101	PAF, KIAA0101, L5, NS5ATP9: PCNA-associated factor	0.027	0.027
ZWINT	N/A	0.027	0.027
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.027	0.029
HD	HD, IT15: Huntingtin	0.027	0.061
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.0263	0.037
ERF	ERF: ETS domain-containing transcription factor ERF	0.026	0.191
GRLF1	N/A	0.026	0.026
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.0425
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.032
PER2	PER2, KIAA0347: Period circadian protein homolog 2	0.026	0.062
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.026	0.077
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.026	0.062
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.026	0.077
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.026	0.123
MDM4	MDM4, MDMX: Mdm4 protein	0.026	0.039
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.026	0.123
GTF3C4	GTF3C4: General transcription factor 3C polypeptide 4	0.026	0.026
MAPK4	MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4	0.026	0.123
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.148
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.025	0.148
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.025
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.025	0.148
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.075
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.025	0.148
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
BCOR	N/A	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.148
LMNA	LMNA, LMN1: Lamin-A/C	0.025	0.025
MAX	MAX: Protein max	0.025	0.047
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.047
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.025	0.148
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.075
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
TCEA1	N/A	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.047
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.148
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
CCNT2	CCNT2: Cyclin-T2	0.025	0.148
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.025	0.075
NUP98	N/A	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.148
ADK	ADK: Adenosine kinase	0.025	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.047
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.075
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
KCTD1		0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.148
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.075
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.075
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.148
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.148
CAMKK1	N/A	0.025	1.33
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.148
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.025	0.148
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.025	0.148
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	1.33
FLJ23436	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.075
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.148
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.025	0.075
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.047
CAMK2A	N/A	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.075
NIPBL	N/A	0.025	0.025
CDC2	CDC2: Cell division control protein 2 homolog	0.025	0.148
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.075
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.075
GRK6	N/A	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	7.88
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
C20orf77	N/A	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	4.22
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.075
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.025	0.075
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.148
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
HDAC7A	N/A	0.025	0.047
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.148
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.075
DIDO1	N/A	0.025	0.075
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.075
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.025	0.148
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.148
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.148
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
GIT2	N/A	0.025	0.025
EEF2K	EEF2K: Elongation factor 2 kinase	0.025	0.075
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.025	0.025
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.075
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.025
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.025	0.148
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
SOX8	SOX8: Transcription factor SOX-8	0.025	0.075
ATXN2L	N/A	0.025	0.025
HTATIP	N/A	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.075
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.075
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.047
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.025	0.148
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.148
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
SEC13L1	N/A	0.025	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.075
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.075
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.075
BRD4	N/A	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.075
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.025	0.025
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.075
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
RNF20		0.025	0.047
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
NES	N/A	0.025	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.025	0.148
SON		0.025	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.148
PRKCB1	N/A	0.025	0.714
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.047
PTTG1	PTTG1, EAP1, PTTG, TUTR1: Securin	0.025	0.053
PTGES3	PTGES3, P23, TEBP: Prostaglandin E synthase 3	0.025	0.025
TACC3	TACC3, ERIC1: Transforming acidic coiled-coil-containing protein 3	0.025	0.025
GMNN	GMNN: Geminin	0.025	0.053
GTSE1	GTSE1: G2 and S phase-expressed protein 1	0.025	0.025
DBF4	DBF4, ASK: Protein DBF4 homolog	0.025	0.025

0.347

Total Score

17.90