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Evidence of Interaction Between LIG1 and H3F3A

The interaction score between LIG1 and H3F3A is 4.23.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between LIG1 and H3F3A = 0.43

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

4.62E-3
Orthology
OrganismLIG1 OrthologueH3F3A OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YDL164C 1 YBR010W 1
bakers yeast YDL164C 1 YNL031C 1
worm Q27474 1 Q10453 0.5
fly Q960P4 1 P84249 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3
Domains No domains were used in calculating likelihood of interaction 0.028
Post-translational Modifications

Protein: LIG1

PTMResidueReference
Phosphorylation 66 PubMed, HPRD
Phosphorylation 76 PubMed, HPRD
Phosphorylation 141 PubMed, HPRD
Phosphorylation 195 PubMed, HPRD
Phosphorylation 911 PubMed, HPRD
Phosphoserine 66 HPRD
Phosphoserine 76 HPRD
Phosphoserine 141 HPRD
Phosphoserine 911 HPRD
Phosphothreonine 195 HPRD

Protein: H3F3A

PTMResidueReference
Acetylation 15 PubMed, HPRD
Methylation 27 PubMed, HPRD
N6-acetyllysine 14 PubMed, HPRD
N6-acetyllysine 23 PubMed, HPRD
N6-methyllysine 9 PubMed, HPRD
N6-methyllysine 27 HPRD
N6-methyllysine 36 PubMed, HPRD
Phosphorylation 11 PubMed, HPRD
Phosphorylation 29 PubMed, HPRD
Localisation

Protein: LIG1

LocalisationReference
Nucleus HPRD
Nucleoplasm HPRD

Protein: H3F3A

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between LIG1 and H3F3A that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between LIG1 andH3F3A. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , LIG1 has 892 interactors and H3F3A has 1286 interactors of which there are 743 common interactors.

Common InteractorName of Common InteractorScore for LIG1-Interactor (?)Score for H3F3A-Interactor (?)
PCNA PCNA: Proliferating cell nuclear antigen 73.00 0.254
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 1.26 0.0818
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.704 0.284
ESPL1 N/A 0.307 0.032
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.307 0.307
DNMT1 DNMT1, AIM, DNMT: DNA 0.307 0.052
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.307 0.070
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.307 0.0425
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.307 0.087
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.307 0.032
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.276 0.038
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.276 16.60
KIF11 N/A 0.276 0.038
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.276 4.15
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.276 0.038
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.276 0.046
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.276 0.029
MCM3 MCM3: DNA replication licensing factor MCM3 0.276 0.046
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.276 0.063
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.276 0.129
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.276 0.046
CBX3 CBX3: Chromobox protein homolog 3 0.276 0.233
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.276 0.129
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.251 0.0425
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.032
TCOF1 N/A 0.144 0.251
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.144 0.032
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.070
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.144 0.0425
MKI67 MKI67: Antigen KI-67 0.144 0.032
SET SET: Protein SET 0.144 0.070
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.144 0.416
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.144 0.307
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.144 0.127
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.144 0.0425
UBAP2 N/A 0.144 0.0425
RBM14 RBM14, SIP: RNA-binding protein 14 0.144 0.087
CENPA CENPA: Histone H3-like centromeric protein A 0.144 0.191
PTMA N/A 0.144 0.852
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.144 0.144
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.141 0.032
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.139 0.063
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.139 0.063
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.129 0.086
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.129 0.078
SSB SSB: Lupus La protein 0.129 0.063
MYBL2 MYBL2, BMYB: Myb-related protein B 0.129 0.038
CDK4 CDK4: Cell division protein kinase 4 0.129 0.038
TIAL1 TIAL1: Nucleolysin TIAR 0.129 0.078
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.129 0.114
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.129 0.063
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.129 0.029
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.129 0.078
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.129 0.372
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.129 0.029
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.129 98.70
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.129 0.425
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.129 0.029
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.129 0.171
CDK2 CDK2: Cell division protein kinase 2 0.129 0.038
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.129 0.078
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.129 0.129
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.129 0.063
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.129 0.461
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.129 0.063
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.129 0.046
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.129 0.129
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.129 0.038
NPM1 NPM1, NPM: Nucleophosmin 0.129 0.029
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.129 0.078
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.129 0.129
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.129 0.046
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.129 0.063
WEE1 WEE1: Wee1-like protein kinase 0.129 0.029
NOL1 N/A 0.129 0.046
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.129 0.233
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.129 0.063
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.078
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.129 0.038
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.129 0.063
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.129 0.129
CCNB1 Cyclin B1 0.129 0.029
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.129 0.038
H2AFX H2AFX, H2AX: Histone H2A.x 0.129 62.90
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.129 0.372
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.129 0.078
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.129 0.078
CDC20 CDC20: Cell division cycle protein 20 homolog 0.129 0.171
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.129 0.038
POLA2 POLA2: DNA polymerase subunit alpha B 0.129 0.046
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.129 0.046
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.129 0.063
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.129 0.129
UNG N/A 0.129 0.038
NUP153 N/A 0.129 0.078
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.129 0.046
HDAC3 HDAC3: Histone deacetylase 3 0.129 0.078
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.129 0.038
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.129 0.063
ROCK1 ROCK1: Rho-associated protein kinase 1 0.127 0.052
PLEK PLEK, P47: Pleckstrin 0.127 0.087
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.114 0.046
SOS1 SOS1: Son of sevenless homolog 1 0.114 0.225
CD2AP CD2AP: CD2-associated protein 0.112 0.245
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.111 0.304
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.091 0.100
CSK CSK: Tyrosine-protein kinase CSK 0.090 0.503
CRKL CRKL: Crk-like protein 0.090 0.245
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.052
NBN NBN, NBS, NBS1, P95: Nibrin 0.087 0.260
ABCF1 N/A 0.087 0.052
KIF23 N/A 0.087 0.032
RB1 RB1: Retinoblastoma-associated protein 0.087 0.070
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.087 0.144
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.087 0.0425
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.087 0.144
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.087 0.052
DDX21 DDX21: Nucleolar RNA helicase 2 0.087 0.087
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.087 0.052
TRRAP N/A 0.087 0.032
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.087 0.070
GNB2L1 Lung cancer oncogene 7 0.087 0.852
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.087 0.070
TOP2B N/A 0.087 0.070
FNBP1 N/A 0.087 0.461
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.086 0.129
DOK1 DOK1: Docking protein 1 0.086 0.078
NF2 NF2, SCH: Merlin 0.083 0.028
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.078 0.070
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.078 0.372
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.078 0.078
MTA1 MTA1: Metastasis-associated protein MTA1 0.078 0.029
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.078 0.078
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.078 0.078
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.276
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.078 0.129
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.078 0.275
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.078 0.129
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.078 0.078
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 0.129
WBSCR20A N/A 0.078 0.063
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.078 0.038
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.078 0.038
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.078 0.063
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.078 0.078
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.078 0.129
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.078 0.078
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.078 3.35
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.078 0.046
TP53 TP53, P53: Cellular tumor antigen p53 0.078 2.54
PHF10 N/A 0.078 0.763
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.078 0.276
PPP1R8 N/A 0.078 0.129
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.461
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.078 45.20
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.078 0.038
HDAC2 HDAC2: Histone deacetylase 2 0.078 0.046
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.078 0.129
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.276
YY1 YY1: Transcriptional repressor protein YY1 0.078 0.276
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.078 0.063
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.078 7.66
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.078 16.60
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.078 0.078
MDN1 MDN1, KIAA0301: Midasin 0.078 0.029
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.078 0.038
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.078 0.078
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.078 0.063
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.078 0.063
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.075 0.081
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.075 0.025
ELMO1 N/A 0.075 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.075 0.025
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.074 0.166
FUBP1 N/A 0.074 0.0446
CXorf9 N/A 0.071 0.461
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.070
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.070 0.070
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.144
KIAA0853 N/A 0.070 0.087
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.070 0.032
CHUK N/A 0.070 0.052
SREBF2 N/A 0.070 0.032
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.070 0.052
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.070 0.052
ELF1 ELF1: ETS-related transcription factor Elf-1 0.070 0.917
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.087
RBM6 RBM6, DEF3: RNA-binding protein 6 0.070 0.052
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.070 0.0425
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.070 0.087
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.070 0.052
ARFGAP1 N/A 0.070 0.070
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.070 0.032
API5 N/A 0.070 0.052
IRF3 IRF3: Interferon regulatory factor 3 0.070 0.052
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.070 0.0425
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.087
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.515
MYB MYB: Myb proto-oncogene protein 0.070 0.0425
TGIF2 TGIF2: Homeobox protein TGIF2 0.070 0.070
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.069 0.046
VAV1 VAV1, VAV: Proto-oncogene vav 0.067 0.503
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.067 0.503
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.067 0.245
XPO1 XPO1, CRM1: Exportin-1 0.066 0.040
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.066 0.067
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.066 0.032
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.066 0.040
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.066 0.040
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.066 0.032
CDC23 CDC23: Cell division cycle protein 23 homolog 0.066 0.032
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.063 0.063
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.063
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.063 0.038
CUL5 CUL5, VACM1: Cullin-5 0.063 0.063
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.063 0.029
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.063
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.063 0.038
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.063 0.029
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.063 0.129
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.063 0.046
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.063 0.129
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.063 0.275
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.078
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.063 0.046
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.063 0.063
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.461
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.063 98.70
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.063 0.038
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.063 0.029
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.063 0.046
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.063 0.029
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.063 0.063
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.063
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.063 0.046
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.063 0.129
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.063 0.078
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.063 0.063
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.063 0.063
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.063 0.078
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.063 0.046
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.063 0.136
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.063 0.276
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.063 0.063
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.063 0.078
SAPS3 N/A 0.063 0.063
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 34.20
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.063 0.276
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.062 0.070
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.061 0.111
GAB2 N/A 0.055 0.052
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.054 1.07
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.054 0.148
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.052 0.070
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.052 0.032
HIVEP1 N/A 0.052 0.032
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.052 0.032
AFF1 N/A 0.052 0.052
NCOA3 N/A 0.052 0.087
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.052 0.144
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.052 0.0425
IFI16 N/A 0.052 0.144
SMARCC2 N/A 0.052 0.0425
SP100 N/A 0.052 0.144
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.052 0.070
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.052 0.052
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.052 0.127
XRCC1 XRCC1: DNA-repair protein XRCC1 0.052 0.210
EMD EMD, EDMD, STA: Emerin 0.052 0.032
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.052 0.070
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.051 0.304
PLD1 PLD1: Phospholipase D1 0.051 0.029
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.051 0.141
MSN MSN: Moesin 0.051 0.066
IRS2 IRS2: Insulin receptor substrate 2 0.049 0.052
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.049 0.109
SNRPA SNRPA: U1 small nuclear ribonucleoprotein A 0.048 0.063
EZH2 EZH2: Enhancer of zeste homolog 2 0.0479 0.070
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.047 0.148
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.046 0.046
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.046 0.129
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.046 0.129
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.046 0.129
SYMPK SYMPK, SPK: Symplekin 0.046 0.029
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.046 0.046
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.046 0.129
POLR2A POLR2A: Uncharacterized protein POLR2A 0.046 0.038
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.046 0.046
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.046 0.063
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.046 0.208
SRF SRF: Serum response factor 0.046 0.046
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.046 0.172
EP300 N/A 0.046 0.704
AIP AIP, XAP2: AH receptor-interacting protein 0.046 0.038
COPB2 COPB2: Coatomer subunit beta' 0.046 0.275
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.046 0.129
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.046 0.188
CDK7 CDK7, MO15: Cell division protein kinase 7 0.046 0.029
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.046 0.029
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.046 390.00
SP3 SP3: Transcription factor Sp3 0.046 0.129
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.038
CSDA CSDA, DBPA: DNA-binding protein A 0.046 0.038
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.046 0.038
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.046 0.063
KIAA1012 KIAA1012: Protein TRS85 homolog 0.046 0.276
DIAPH1 Diaphanous 1 0.046 0.129
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.046 0.078
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.046 0.029
RPS6KB1 N/A 0.046 0.078
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.046 0.038
RUNX1 N/A 0.046 0.046
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.046 0.063
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.078
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.046 0.078
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.046 20.40
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.046 0.063
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.063
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.046 0.078
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.046 0.129
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.046 0.029
KLHDC4 N/A 0.046 0.078
RBM7 0.046 0.038
ARMET ARMET, ARP: Protein ARMET precursor 0.046 0.038
CUL4B N/A 0.046 0.063
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.046 0.038
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.046 0.063
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.046 0.078
TAL1 TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1 0.046 0.038
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.046 0.038
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.046 0.100
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.046 0.274
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.0453 0.027
VASP VASP: Vasodilator-stimulated phosphoprotein 0.0453 0.036
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.0446 0.027
PHB2 PHB2, BAP, REA: Prohibitin-2 0.0446 0.027
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.044 0.098
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.044 0.098
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.044 0.098
GTF2F2 N/A 0.0425 0.0425
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.070
COIL COIL, CLN80: Coilin 0.0425 0.0425
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.0425 0.475
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.0425 0.032
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.0425 0.0425
H1FX H1FX: Histone H1x 0.0425 0.307
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.0425 0.127
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.0425 0.087
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.0425 0.0425
ERG ERG: Transcriptional regulator ERG 0.0425 0.096
ZNF267 ZNF267: Zinc finger protein 267 0.0425 0.0425
STK16 N/A 0.0425 0.032
WDR1 N/A 0.0425 0.515
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.0425 0.144
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.0425 0.070
NFATC1 N/A 0.0425 0.210
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.041 0.064
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.041 0.113
PSCD4 PSCD4, CYT4: Cytohesin-4 0.041 0.066
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.041 0.073
PLD2 PLD2: Phospholipase D2 0.041 0.041
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.04 0.109
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.04 0.109
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.04 0.109
AMPH AMPH, AMPH1: Amphiphysin 0.04 0.109
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.04 0.109
FRG1 FRG1: Protein FRG1 0.040 0.066
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.040 0.040
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.040 0.032
RPL8 RPL8: 60S ribosomal protein L8 0.040 0.066
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.040 0.066
QARS QARS: Glutaminyl-tRNA synthetase 0.040 0.066
HNRPK N/A 0.040 0.141
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.040 0.154
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.040 0.032
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.040 0.066
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.040 0.066
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.040 0.040
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.040 0.066
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.040 0.032
THOC1 THOC1, HPR1: THO complex subunit 1 0.040 0.032
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.040 0.066
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.040 0.032
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.040 0.032
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.040 0.066
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.040 0.066
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.038 0.038
BRPF1 BRPF1, BR140: Peregrin 0.038 0.372
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.038 0.111
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.038 0.063
SOX4 SOX4: Transcription factor SOX-4 0.038 0.038
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.038 0.063
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.038 0.078
MYH9 MYH9: Myosin-9 0.038 0.063
ZNF551 N/A 0.038 0.029
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 0.038 66.10
ZNF335 ZNF335: Zinc finger protein 335 0.038 0.029
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.038 0.029
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 0.038 0.038
MAFG MAFG: Transcription factor MafG 0.038 0.063
PCAF PCAF: Histone acetyltransferase PCAF 0.038 30.10
RELA RELA, NFKB3: Transcription factor p65 0.038 0.139
RANBP9 RANBP9, RANBPM: Ran-binding protein 9 0.038 0.136
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.038 1.62
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.038 0.129
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.038 0.063
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.038 0.063
COPA COPA: Coatomer subunit alpha 0.038 0.372
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.038 0.129
COPE COPE: Coatomer subunit epsilon 0.038 0.063
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.038 0.078
CDK6 CDK6: Cell division protein kinase 6 0.038 0.029
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.038 3.35
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.038 0.046
FZR1 N/A 0.038 0.038
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.038 0.038
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.038 0.063
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.038 0.114
SATB1 SATB1: DNA-binding protein SATB1 0.038 0.038
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.038 0.046
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.038 0.129
SEC31L1 N/A 0.038 0.372
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.038 0.129
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.038 0.063
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.038 0.276
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.038 0.129
ATM ATM: Serine-protein kinase ATM 0.038 0.038
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.038 0.029
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.037 0.274
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.037 0.561
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.037 0.340
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.037 0.126
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.037 0.074
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.036 0.051
YWHAQ YWHAQ: 14-3-3 protein theta 0.036 0.027
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.036 0.098
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.036 0.098
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.036 0.098
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.036 0.098
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.036 0.098
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.036 0.098
LYN LYN: Tyrosine-protein kinase Lyn 0.033 1.07
STAM2 STAM2: Signal transducing adapter molecule 2 0.033 0.113
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.033 0.113
NCK2 NCK2: Cytoplasmic protein NCK2 0.033 0.181
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.033 0.064
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.032 0.0425
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.032 0.062
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.032 0.087
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.052
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.032 0.070
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.032 0.0425
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.032 0.052
PRKAA1 N/A 0.032 0.032
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.032 0.260
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.032 0.087
ZFX ZFX: Zinc finger X-chromosomal protein 0.032 0.0425
GTF3C1 N/A 0.032 0.052
RGS14 N/A 0.032 0.052
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.032 0.052
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.032 0.026
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.032 0.026
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.032 0.032
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.032 0.052
MECP2 MECP2: Methyl-CpG-binding protein 2 0.032 0.032
STAT2 STAT2: Signal transducer and activator of transcription 2 0.032 0.032
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.032 0.0425
XRCC4 N/A 0.032 0.032
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.032 0.141
RPS10 RPS10: 40S ribosomal protein S10 0.032 0.066
THOP1 THOP1: Thimet oligopeptidase 0.032 0.051
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.032 0.040
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.032 0.066
PPARBP N/A 0.032 0.040
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.032 0.066
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.032 0.040
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.032 0.040
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.032 0.032
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.032 0.040
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.032 0.503
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.032 0.032
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.032 0.032
VCP VCP: Transitional endoplasmic reticulum ATPase 0.032 8.55
EEF2 EEF2, EF2: Elongation factor 2 0.032 0.075
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.0308 0.372
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.0308 0.078
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.029 0.233
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.029 0.063
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.029 0.461
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.029 0.038
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.029 0.046
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.029
RCP9 CRCP: DNA-directed RNA polymerase III subunit RPC9 0.029 0.029
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.029 0.425
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.029 0.046
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.029 0.063
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.029 0.078
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.029 49.80
STK10 STK10: Uncharacterized protein STK10 0.029 0.129
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.029 0.763
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.029 0.038
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.029 0.029
POLB POLB: DNA polymerase beta 0.029 0.038
MTF1 MTF1: Metal regulatory transcription factor 1 0.029 0.078
CORO1C CORO1C, CRNN4: Coronin-1C 0.029 98.70
GSK3B N/A 0.029 0.078
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.046
CCNH CCNH: Cyclin-H 0.029 0.029
ETS1 ETS1, EWSR2: Protein C-ets-1 0.029 0.114
WDR44 WDR44: WD repeat-containing protein 44 0.029 0.063
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.029 0.046
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.029 0.129
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.029 0.461
CREBBP CREBBP, CBP: CREB-binding protein 0.029 0.188
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.029 0.029
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.029 0.171
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.029 0.063
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.165
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
CABLES1 N/A 0.028 0.028
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.028
C20orf18 N/A 0.028 0.083
UHRF1 0.028 0.165
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.028 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.165
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.152
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
C13orf8 N/A 0.028 0.028
PPEF1 N/A 0.028 0.028
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.028
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
ZNF265 N/A 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
HDAC8 N/A 0.028 0.028
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
SNRPB N/A 0.028 0.028
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.028 0.083
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
WDR54 N/A 0.028 0.165
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.028 0.083
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.028
CORO6 N/A 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
IRF7 N/A 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.165
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.028 0.028
DUSP15 N/A 0.028 0.028
RAB4A N/A 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
BID BID: BH3-interacting domain death agonist 0.028 0.028
MAPK15 N/A 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.165
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.028
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.028 0.083
PHLDB2 N/A 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.028
HES6 HES6: Transcription cofactor HES-6 0.028 0.028
KIF1B N/A 0.028 0.028
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.028 0.152
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.028 0.088
SORBS3 SORBS3, SCAM1: Vinexin 0.027 0.064
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.027 0.503
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.027 0.065
HD HD, IT15: Huntingtin 0.027 0.027
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.0263 0.072
ERF ERF: ETS domain-containing transcription factor ERF 0.026 0.096
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.026 0.087
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.026
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.032
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.026 0.026
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.026 0.052
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.026 0.052
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.026 0.052
MARK2 N/A 0.026 0.070
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.025 0.025
MAP2K3 N/A 0.025 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.025 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.148
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
RBL1 RBL1: Retinoblastoma-like protein 1 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
BCOR N/A 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.025 0.025
MAX MAX: Protein max 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.148
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.025
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.025 0.025
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.025
TCEA1 N/A 0.025 0.025
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.025 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.075
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.025 0.137
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
CCNT2 CCNT2: Cyclin-T2 0.025 0.025
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.025 0.137
NUP98 N/A 0.025 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.148
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
KCTD1 0.025 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.025
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.025 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.025
CAMKK1 N/A 0.025 0.025
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 6.64
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
FLJ23436 N/A 0.025 0.025
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.025 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.025
CAMK2A N/A 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
NIPBL N/A 0.025 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.075
GRK6 N/A 0.025 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.137
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
C20orf77 N/A 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.148
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.025
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.025
HDAC7A N/A 0.025 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.025 6.64
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.025 0.025
DIDO1 N/A 0.025 0.148
TFAP4 TFAP4: Transcription factor AP-4 0.025 0.025
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
GIT2 N/A 0.025 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.025 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 7.88
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 1.33
SOX8 SOX8: Transcription factor SOX-8 0.025 0.025
ATXN2L N/A 0.025 0.025
HTATIP N/A 0.025 6.64
CREB1 CREB1: cAMP response element-binding protein 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.025 0.148
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.025
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.025 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
SEC13L1 N/A 0.025 0.025
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.148
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.148
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.025
BRD4 N/A 0.025 3.97
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.025 0.137
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
RNF20 0.025 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.148
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
NES N/A 0.025 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.025 0.025
SON 0.025 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.025
PRKCB1 N/A 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.025
NOLC1 NOLC1, KIAA0035: Nucleolar phosphoprotein p130 0.025 0.0955
PTTG1 PTTG1, EAP1, PTTG, TUTR1: Securin 0.025 0.044
0.228
Total Score 4.23