PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between LIG1 and CDK6

The interaction score between LIG1 and CDK6 is 5.28.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between LIG1 and CDK6 = 0.30

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

3.80E-3

Orthology

Organism	LIG1 Orthologue		CDK6 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
fly	Q960P4	1	Q94877	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

No domains were used in calculating likelihood of interaction

0.028

Post-translational Modifications

Protein: LIG1

PTM	Residue	Reference
Phosphorylation	66	PubMed, HPRD
Phosphorylation	76	PubMed, HPRD
Phosphorylation	141	PubMed, HPRD
Phosphorylation	195	PubMed, HPRD
Phosphorylation	911	PubMed, HPRD
Phosphoserine	66	HPRD
Phosphoserine	76	HPRD
Phosphoserine	141	HPRD
Phosphoserine	911	HPRD
Phosphothreonine	195	HPRD

Protein: CDK6

PTM	Residue	Reference
Phosphotyrosine	13	HPRD
Phosphotyrosine	24	HPRD

Localisation

Protein: LIG1

Localisation	Reference
Nucleus	HPRD
Nucleoplasm	HPRD

Protein: CDK6

Localisation	Reference
Nucleus	HPRD
Cytoplasm	HPRD

Transitive Score

The common interactors between LIG1 and CDK6 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between LIG1 andCDK6. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , LIG1 has 892 interactors and CDK6 has 1084 interactors of which there are 651 common interactors.

Common Interactor	Name of Common Interactor	Score for LIG1-Interactor (?)	Score for CDK6-Interactor (?)
PCNA	PCNA: Proliferating cell nuclear antigen	73.00	0.029
UBE2R2	UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2	3.39	0.025
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	1.26	0.029
ESPL1	N/A	0.307	0.026
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.307	0.032
DNMT1	DNMT1, AIM, DNMT: DNA	0.307	0.032
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.307	0.191
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.307	0.127
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.307	0.0425
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.307	0.096
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.276	0.029
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.276	0.029
KIF11	N/A	0.276	0.029
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.276	0.029
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.276	0.038
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.276	0.071
MCM3	MCM3: DNA replication licensing factor MCM3	0.276	0.071
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.276	0.038
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.276	0.038
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.038
CBX3	CBX3: Chromobox protein homolog 3	0.276	0.038
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.276	0.038
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.191	0.123
TCOF1	N/A	0.144	0.032
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.144	0.032
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.0425
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.144	0.032
MKI67	MKI67: Antigen KI-67	0.144	0.048
SET	SET: Protein SET	0.144	0.026
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.144	0.032
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.144	0.026
UBAP2	N/A	0.144	0.052
RBM14	RBM14, SIP: RNA-binding protein 14	0.144	0.0425
CENPA	CENPA: Histone H3-like centromeric protein A	0.144	0.026
PTMA	N/A	0.144	0.080
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.144	0.251
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.141	0.086
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.139	0.171
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.139	0.111
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.129	0.0425
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.129	0.038
SSB	SSB: Lupus La protein	0.129	0.038
CDK4	CDK4: Cell division protein kinase 4	0.129	0.038
TIAL1	TIAL1: Nucleolysin TIAR	0.129	0.029
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.129	0.032
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.129	0.029
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	0.029
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.129	0.038
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.129	0.029
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.129	0.069
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.129	0.158
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.129	0.038
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.129	0.029
CDK2	CDK2: Cell division protein kinase 2	0.129	0.029
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.038
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.129	0.038
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.129	0.029
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.129	0.038
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.129	0.038
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.129	0.038
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.086
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.038
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.129	0.038
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.129	0.086
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.129	0.029
WEE1	WEE1: Wee1-like protein kinase	0.129	0.038
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.129	0.046
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.038
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.038
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.129	0.038
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.129	0.038
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.129	0.038
CCNB1	Cyclin B1	0.129	0.136
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.129	0.043
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.129	0.038
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.129	0.029
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.129	0.029
CDC20	CDC20: Cell division cycle protein 20 homolog	0.129	0.069
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.129	0.029
POLA2	POLA2: DNA polymerase subunit alpha B	0.129	0.029
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.129	0.029
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.129	0.038
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.029
UNG	N/A	0.129	0.052
NUP153	N/A	0.129	0.038
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.038
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.038
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.129	0.029
ROCK1	ROCK1: Rho-associated protein kinase 1	0.127	0.152
PLEK	PLEK, P47: Pleckstrin	0.127	0.152
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.114	0.171
SOS1	SOS1: Son of sevenless homolog 1	0.114	0.136
CD2AP	CD2AP: CD2-associated protein	0.112	0.077
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.111	0.171
DAB1	DAB1: Disabled homolog 1	0.111	0.111
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.097	0.111
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.091	0.096
CSK	CSK: Tyrosine-protein kinase CSK	0.090	0.136
CRKL	CRKL: Crk-like protein	0.090	0.171
DAB2	DAB2, DOC2: Disabled homolog 2	0.088	0.111
APBA2	APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2	0.088	0.088
MATR3	MATR3, KIAA0723: Matrin-3	0.087	0.026
NBN	NBN, NBS, NBS1, P95: Nibrin	0.087	0.048
ABCF1	N/A	0.087	0.032
KIF23	N/A	0.087	0.032
RB1	RB1: Retinoblastoma-associated protein	0.087	0.077
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.087	0.032
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.087	0.052
DDX21	DDX21: Nucleolar RNA helicase 2	0.087	0.0425
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.087	0.032
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.087	0.026
GNB2L1	Lung cancer oncogene 7	0.087	0.032
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.032
TOP2B	N/A	0.087	0.0425
FNBP1	N/A	0.087	0.056
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.086	0.136
DOK1	DOK1: Docking protein 1	0.086	0.171
NF2	NF2, SCH: Merlin	0.083	0.165
MAPK8IP1	MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1	0.078	0.088
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.078	0.032
MTA1	MTA1: Metastasis-associated protein MTA1	0.078	0.029
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.078	0.029
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.078	0.029
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.078	0.029
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.078	0.029
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.078	0.114
WBSCR20A	N/A	0.078	0.029
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.078	0.0425
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.078	0.038
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.038
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.038
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.078	0.029
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.078	0.029
PHF10	N/A	0.078	0.046
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.038
PPP1R8	N/A	0.078	0.054
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.029
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.078	0.029
HDAC2	HDAC2: Histone deacetylase 2	0.078	0.038
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.038
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.078	0.038
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.029
YY1	YY1: Transcriptional repressor protein YY1	0.078	0.038
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.078	0.029
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	0.029
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.078	0.038
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.078	0.038
MDN1	MDN1, KIAA0301: Midasin	0.078	0.029
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.078	0.038
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.069
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.078	0.086
PLEKHA5	PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member	0.077	0.109
PLCG1	PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	0.075	0.109
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.075	0.148
ELMO1	N/A	0.075	0.148
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.075	0.148
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.074	0.109
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.074	0.048
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.026
FUBP1	N/A	0.074	0.032
CXorf9	N/A	0.071	0.056
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.070	0.032
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.070	0.0425
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.032
KIAA0853	N/A	0.070	0.0425
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.070	0.026
CHUK	N/A	0.070	0.0425
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.070	0.039
ELF1	ELF1: ETS-related transcription factor Elf-1	0.070	0.096
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.070	0.0425
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.032
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.0425
ARFGAP1	N/A	0.070	0.096
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.070	0.077
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.070	0.026
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.0425
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.070	0.032
MYB	MYB: Myb proto-oncogene protein	0.070	0.155
TBC1D1	TBC1D1, KIAA1108: TBC1 domain family member 1	0.070	0.042
ELMO2	ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2	0.069	0.111
RAPGEF6	RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6	0.067	0.069
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.067	0.111
VIL2	N/A	0.067	0.111
OSBP	OSBP, OSBP1: Oxysterol-binding protein 1	0.067	0.171
VAV1	VAV1, VAV: Proto-oncogene vav	0.067	0.136
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.067	0.086
NCK1	NCK1, NCK: Cytoplasmic protein NCK1	0.067	0.136
XPO1	XPO1, CRM1: Exportin-1	0.066	0.038
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.066	0.032
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.043
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.066	0.029
HSPD1		0.066	0.029
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.066	0.038
TK1	TK1: Thymidine kinase, cytosolic	0.066	0.026
LDHB	LDHB: L-lactate dehydrogenase B chain	0.066	0.029
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.139
CTPS	CTPS: CTP synthase 1	0.066	0.086
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.066	0.136
CDC23	CDC23: Cell division cycle protein 23 homolog	0.066	0.038
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.063	0.029
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.063	0.048
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.063	0.225
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.191
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.063	0.038
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.029
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.063	0.038
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.063	0.038
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.063	0.029
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.029
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.063	0.029
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.063	0.038
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.063	0.029
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.029
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.029
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.063	0.029
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.029
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.063	0.038
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.063	0.029
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.063	0.038
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.063	0.038
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.063	0.038
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.086
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.062	0.109
GAB1	GAB1: GRB2-associated-binding protein 1	0.062	0.152
SPTA1	SPTA1, SPTA: Spectrin alpha chain, erythrocyte	0.061	0.062
ARHGEF12	ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12	0.055	0.098
GAB2	N/A	0.055	0.152
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.054	0.069
GRAP2	GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2	0.054	0.109
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.052	0.0425
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.052	0.0425
HIVEP1	N/A	0.052	0.032
AFF1	N/A	0.052	0.032
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.052	0.032
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.052	0.077
SMARCC2	N/A	0.052	0.026
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.052	0.062
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.052	0.032
XRCC1	XRCC1: DNA-repair protein XRCC1	0.052	0.032
EMD	EMD, EDMD, STA: Emerin	0.052	0.032
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.032
SHC1	SHC1, SHC, SHCA: SHC-transforming protein 1	0.051	0.051
ARHGEF6	ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6	0.051	0.225
APS	SH2B2, APS: SH2B adapter protein 2	0.051	0.097
PLD1	PLD1: Phospholipase D1	0.051	0.097
WAS	WAS, IMD2: Wiskott-Aldrich syndrome protein	0.051	0.136
MSN	MSN: Moesin	0.051	0.136
IRS1	IRS1: Insulin receptor substrate 1	0.049	0.098
IRS2	IRS2: Insulin receptor substrate 2	0.049	0.152
ITSN1	ITSN1, ITSN, SH3D1A: Intersectin-1	0.049	0.165
DNM3	DNM3: Uncharacterized protein DNM3	0.049	0.165
LNK	SH2B3, LNK: SH2B adapter protein 3	0.049	0.165
PSCD1	PSCD1, D17S811E: Cytohesin-1	0.049	0.165
PSCD2	N/A	0.049	0.165
SIPA1L1	SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein	0.049	0.049
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.046	0.114
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.046	0.029
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.046	0.136
SYMPK	SYMPK, SPK: Symplekin	0.046	0.046
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.046	0.029
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.046	0.029
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.046	0.046
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.046	0.034
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.046	0.029
SRF	SRF: Serum response factor	0.046	0.029
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.046	0.077
EP300	N/A	0.046	0.038
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.046	0.029
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.046	0.027
WDR79	N/A	0.046	0.029
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.046	0.026
CSDA	CSDA, DBPA: DNA-binding protein A	0.046	0.038
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.046	0.029
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.046	0.029
KIAA1012	KIAA1012: Protein TRS85 homolog	0.046	0.029
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.046	0.029
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.046	0.039
RPS6KB1	N/A	0.046	0.029
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.046	0.029
RUNX1	N/A	0.046	0.063
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.029
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.046	0.029
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.029
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.046	0.029
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.046	0.069
KLHDC4	N/A	0.046	0.029
FKBP4	FKBP4: FK506-binding protein 4	0.046	0.038
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.046	0.069
TAL1	TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1	0.046	0.029
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.046	0.123
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.046	0.0416
SLC9A3R1	SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50	0.0453	0.026
VASP	VASP: Vasodilator-stimulated phosphoprotein	0.0453	0.123
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.0446	0.032
PHB2	PHB2, BAP, REA: Prohibitin-2	0.0446	0.032
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.0446	0.096
ROCK2	ROCK2, KIAA0619: Rho-associated protein kinase 2	0.044	0.097
TIAM1	TIAM1: T-lymphoma invasion and metastasis-inducing protein 1	0.044	0.097
EPB41L1	EPB41L1, KIAA0338: Band 4.1-like protein 1	0.044	0.148
GOPC	GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein	0.044	0.028
PARD6A	PARD6A, PAR6A: Partitioning defective 6 homolog alpha	0.044	0.148
MYO18A		0.044	0.025
RASA1	RASA1, RASA: Ras GTPase-activating protein 1	0.044	0.148
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.044	0.148
LRRC7	LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7	0.044	0.025
ITSN2	ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2	0.044	0.148
SPTBN1	SPTBN1, SPTB2: Spectrin beta chain, brain 1	0.044	0.148
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.044	0.148
GTF2F2	N/A	0.0425	0.026
COIL	COIL, CLN80: Coilin	0.0425	0.0425
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.0425	0.026
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.0425	0.032
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.0425	0.032
H1FX	H1FX: Histone H1x	0.0425	0.096
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.0425	0.026
ERG	ERG: Transcriptional regulator ERG	0.0425	0.030
WDR1	N/A	0.0425	0.026
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.0425	0.032
NFATC1	N/A	0.0425	0.077
DNMBP	DNMBP, KIAA1010: Dynamin-binding protein	0.041	0.055
STAM	STAM, STAM1: Signal transducing adapter molecule 1	0.041	0.069
PLCB3	PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3	0.041	0.171
IQSEC1	IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein	0.041	0.097
PSCD4	PSCD4, CYT4: Cytohesin-4	0.041	0.136
ARHGAP12	ARHGAP12: Rho GTPase-activating protein 12	0.041	0.097
PLD2	PLD2: Phospholipase D2	0.041	0.111
RDX	RDX: Radixin	0.041	0.097
RASA3	RASA3: Ras GTPase-activating protein 3	0.041	0.097
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.04	0.056
ABI1	ABI1, SSH3BP1: Abl interactor 1	0.04	0.083
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.04	0.165
AMPH	AMPH, AMPH1: Amphiphysin	0.04	0.083
SLA2	SLA2, C20orf156, SLAP2: Src-like-adapter 2	0.04	0.165
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.225
CASP3	CASP3, CPP32: Caspase-3 precursor	0.040	0.029
RPL8	RPL8: 60S ribosomal protein L8	0.040	0.029
QARS	QARS: Glutaminyl-tRNA synthetase	0.040	0.046
HNRPK	N/A	0.040	0.029
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.040	0.032
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.040	0.029
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.040	0.038
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.040	0.029
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.040	0.171
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	0.040	0.029
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.040	0.029
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.040	0.136
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.040	0.029
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.040	0.029
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.040	0.038
HSP90AA1	Hsp89-alpha-delta-N	0.040	0.086
THOC1	THOC1, HPR1: THO complex subunit 1	0.040	0.139
EEF1B2	EEF1B2, EEF1B, EF1B: Elongation factor 1-beta	0.040	0.029
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.040	0.136
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.040	0.026
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.040	0.038
BRPF1	BRPF1, BR140: Peregrin	0.038	0.029
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.038	0.086
SOX4	SOX4: Transcription factor SOX-4	0.038	0.038
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.038	0.029
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.038	0.029
ZNF335	ZNF335: Zinc finger protein 335	0.038	0.026
RELA	RELA, NFKB3: Transcription factor p65	0.038	0.056
RANBP9	RANBP9, RANBPM: Ran-binding protein 9	0.038	0.029
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.038	0.029
METTL1	METTL1, C12orf1: tRNA	0.038	0.029
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.038	0.029
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.038	0.029
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.038	0.069
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.038	0.111
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.063
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.038	0.029
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.038	0.029
ATM	ATM: Serine-protein kinase ATM	0.038	0.056
NCF1	Neutrophil cytosolic factor 1 variant (Fragment)	0.037	0.062
PSTPIP1	PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1	0.037	0.077
SLA	SLA, SLAP, SLAP1: SRC-like-adapter	0.037	0.152
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.037	0.191
SH3BP2	SH3BP2: Uncharacterized protein SH3BP2	0.037	0.152
IRS4	IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4	0.037	0.109
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.036	0.077
YWHAQ	YWHAQ: 14-3-3 protein theta	0.036	0.026
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.036	0.026
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.052
IPO7	IPO7: Uncharacterized protein IPO7	0.036	0.032
BIN1	BIN1, AMPHL: Myc box-dependent-interacting protein 1	0.036	0.075
BAIAP2	BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2	0.036	0.075
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.036	0.165
NEDD9	NEDD9, CASL: Enhancer of filamentation 1	0.036	0.075
GRB2	GRB2, ASH: Growth factor receptor-bound protein 2	0.036	0.148
SH3KBP1	SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1	0.036	0.083
LYN	LYN: Tyrosine-protein kinase Lyn	0.033	0.152
STAM2	STAM2: Signal transducing adapter molecule 2	0.033	0.086
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.033	0.111
NCK2	NCK2: Cytoplasmic protein NCK2	0.033	0.097
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	0.033	0.111
NOS1	NOS1: Nitric-oxide synthase, brain	0.033	0.055
MCF2	MCF2, DBL: Proto-oncogene DBL	0.032	0.033
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.032	0.0425
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.032	0.096
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.032	0.152
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.096
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.032	0.026
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.032	0.026
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.032	0.026
PRKAA1	N/A	0.032	0.026
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.032	0.026
ZFX	ZFX: Zinc finger X-chromosomal protein	0.032	0.032
GTF3C1	N/A	0.032	0.026
RGS14	N/A	0.032	0.026
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.032	0.077
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.032	0.096
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.032	0.032
STAT2	STAT2: Signal transducer and activator of transcription 2	0.032	0.191
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.032	0.029
RPS10	RPS10: 40S ribosomal protein S10	0.032	0.086
THOP1	THOP1: Thimet oligopeptidase	0.032	0.032
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.032	0.029
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.032	0.029
PPARBP	N/A	0.032	0.038
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.032	0.029
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.032	0.038
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.032	0.086
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.032	0.038
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.032	0.225
EEF2	EEF2, EF2: Elongation factor 2	0.032	0.029
MAP3K11	MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11	0.0308	0.069
PLCB1	PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-	0.029	0.088
PRKD1	PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1	0.029	0.097
BMX	N/A	0.029	0.098
EPB41L2	EPB41L2: Band 4.1-like protein 2	0.029	0.097
WASL	WASL: Neural Wiskott-Aldrich syndrome protein	0.029	0.111
EIF4G3	EIF4G3: Eukaryotic translation initiation factor 4 gamma 3	0.029	0.069
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.029	0.086
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.029	0.026
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.029	0.086
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.029	0.056
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.029	0.171
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.029	0.046
GATA2	N/A	0.029	0.046
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.029	0.026
POLB	POLB: DNA polymerase beta	0.029	0.026
MTF1	MTF1: Metal regulatory transcription factor 1	0.029	0.032
GSK3B	N/A	0.029	0.029
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.029	0.086
CCNH	CCNH: Cyclin-H	0.029	0.136
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.029	0.029
ETS1	ETS1, EWSR2: Protein C-ets-1	0.029	0.069
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.029	0.029
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.029	0.062
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.029	0.069
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
CABLES1	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.165
C20orf18	N/A	0.028	0.028
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.028	0.083
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
C13orf8	N/A	0.028	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.028
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.028
MAPKAPK5	N/A	0.028	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.052
ZNF265	N/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
HDAC8	N/A	0.028	0.028
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
SNRPB	N/A	0.028	0.028
DSP	DSP: Desmoplakin	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.028	0.083
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
WDR54	N/A	0.028	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.028	0.083
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
DUSP15	N/A	0.028	0.028
RAB4A	N/A	0.028	0.052
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
MAPK15	N/A	0.028	0.083
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.028
PHLDB2	N/A	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.028
HES6	HES6: Transcription cofactor HES-6	0.028	0.028
KIF1B	N/A	0.028	0.028
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.028	0.174
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.028	0.055
SORBS3	SORBS3, SCAM1: Vinexin	0.027	0.055
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.027	0.152
PIK3R2	PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta	0.027	0.097
SRA1	APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3	0.027	0.027
APBB1	APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1	0.027	0.027
HD	HD, IT15: Huntingtin	0.027	0.032
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.0263	0.109
CNKSR2	CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2	0.026	0.097
PSD	TYL: TYL protein	0.026	0.088
SNTA1	SNTA1, SNT1: Alpha-1-syntrophin	0.026	0.088
ERF	ERF: ETS domain-containing transcription factor ERF	0.026	0.096
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.026	0.032
GRLF1	N/A	0.026	0.077
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.026
PER2	PER2, KIAA0347: Period circadian protein homolog 2	0.026	0.0425
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.026	0.0425
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.026	0.031
MDM4	MDM4, MDMX: Mdm4 protein	0.026	0.062
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.026	0.026
MAPK4	MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4	0.026	0.026
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.025
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.025	0.148
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.025	0.075
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
BCOR	N/A	0.025	0.028
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.025
MAX	MAX: Protein max	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.025
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.025	0.075
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.025
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
TCEA1	N/A	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.025	0.137
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
CCNT2	CCNT2: Cyclin-T2	0.025	0.148
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.025	0.025
NUP98	N/A	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.075
ADK	ADK: Adenosine kinase	0.025	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
KCTD1		0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.025
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.025	0.148
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.075
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.025
CAMKK1	N/A	0.025	0.028
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.025	0.148
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.025	0.165
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
FLJ23436	N/A	0.025	0.028
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.025	0.025
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.025
CAMK2A	N/A	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.025
CDC2	CDC2: Cell division control protein 2 homolog	0.025	0.028
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025
GRK6	N/A	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	0.148
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
C20orf77	N/A	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.148
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.025
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.025	0.028
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.075
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
HDAC7A	N/A	0.025	0.028
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.047
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.025
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.028
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.025	0.028
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.025
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
GIT2	N/A	0.025	0.075
EEF2K	EEF2K: Elongation factor 2 kinase	0.025	0.165
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.025	0.165
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
ATXN2L	N/A	0.025	0.025
HTATIP	N/A	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.165
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.028
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.025
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.025	0.028
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.028
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.025
BRD4	N/A	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.025	0.137
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.028
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
RNF20		0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.028
NES	N/A	0.025	0.028
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.025	0.148
SON		0.025	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.075
PRKCB1	N/A	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.025

0.347

Total Score

5.28